| mitochondrion organization | GO:0007005 | 4 | 0.210 | Yeast |
| larval development | GO:0002164 | 2 | 0.162 | Worm |
| negative regulation of cellular process | GO:0048523 | 283 | 0.145 | |
| negative regulation of biological process | GO:0048519 | 304 | 0.140 | |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.124 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 3 | 0.105 | |
| cellular protein catabolic process | GO:0044257 | 4 | 0.088 | |
| signal transduction | GO:0007165 | 455 | 0.082 | |
| mitochondrial transport | GO:0006839 | 2 | 0.080 | Yeast |
| regulation of protein ubiquitination | GO:0031396 | 3 | 0.077 | |
| regulation of response to stimulus | GO:0048583 | 269 | 0.076 | |
| regulation of metabolic process | GO:0019222 | 359 | 0.075 | |
| gene expression | GO:0010467 | 252 | 0.071 | |
| single organism organelle organization | GO:1902589 | 199 | 0.070 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 4 | 0.069 | |
| establishment of localization | GO:0051234 | 244 | 0.069 | Yeast |
| cell death | GO:0008219 | 121 | 0.066 | |
| death | GO:0016265 | 121 | 0.064 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 191 | 0.063 | |
| ion transport | GO:0006811 | 114 | 0.062 | |
| aging | GO:0007568 | 2 | 0.058 | |
| rna metabolic process | GO:0016070 | 219 | 0.058 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 271 | 0.056 | Worm |
| cellular nitrogen compound metabolic process | GO:0034641 | 290 | 0.056 | |
| programmed cell death | GO:0012501 | 119 | 0.054 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 3 | 0.052 | |
| carboxylic acid metabolic process | GO:0019752 | 22 | 0.051 | |
| positive regulation of biological process | GO:0048518 | 253 | 0.051 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 4 | 0.051 | |
| regulation of protein complex assembly | GO:0043254 | 3 | 0.051 | |
| transport | GO:0006810 | 220 | 0.045 | Yeast |
| modification dependent macromolecule catabolic process | GO:0043632 | 3 | 0.044 | |
| cellular respiration | GO:0045333 | 3 | 0.044 | |
| nitrogen compound metabolic process | GO:0006807 | 319 | 0.043 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 3 | 0.042 | |
| hemopoiesis | GO:0030097 | 183 | 0.042 | |
| regulation of signal transduction | GO:0009966 | 225 | 0.042 | |
| cellular nitrogen compound biosynthetic process | GO:0044271 | 218 | 0.041 | |
| regulation of multicellular organism growth | GO:0040014 | 4 | 0.041 | |
| heterocycle metabolic process | GO:0046483 | 290 | 0.039 | |
| nucleobase containing compound metabolic process | GO:0006139 | 274 | 0.038 | |
| cellular component biogenesis | GO:0044085 | 178 | 0.038 | |
| regulation of developmental process | GO:0050793 | 247 | 0.038 | |
| protein metabolic process | GO:0019538 | 183 | 0.037 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 3 | 0.035 | |
| regulation of cell activation | GO:0050865 | 1 | 0.035 | |
| regulation of cell communication | GO:0010646 | 232 | 0.035 | |
| locomotion | GO:0040011 | 313 | 0.034 | |
| rna biosynthetic process | GO:0032774 | 181 | 0.033 | |
| immune system process | GO:0002376 | 241 | 0.033 | |
| cellular component movement | GO:0006928 | 335 | 0.032 | |
| response to drug | GO:0042493 | 3 | 0.032 | |
| protein polyubiquitination | GO:0000209 | 4 | 0.031 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 3 | 0.031 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.031 | |
| immune system development | GO:0002520 | 191 | 0.030 | |
| regulation of binding | GO:0051098 | 3 | 0.030 | |
| nucleic acid metabolic process | GO:0090304 | 244 | 0.030 | |
| morphogenesis of an epithelium | GO:0002009 | 333 | 0.030 | |
| regulation of cellular metabolic process | GO:0031323 | 320 | 0.029 | |
| multicellular organism growth | GO:0035264 | 4 | 0.029 | |
| establishment of protein localization to organelle | GO:0072594 | 4 | 0.029 | Yeast |
| regulation of primary metabolic process | GO:0080090 | 311 | 0.029 | |
| b cell differentiation | GO:0030183 | 1 | 0.029 | |
| cellular response to nutrient levels | GO:0031669 | 2 | 0.029 | |
| cellular macromolecule biosynthetic process | GO:0034645 | 224 | 0.029 | |
| protein k48 linked ubiquitination | GO:0070936 | 1 | 0.028 | |
| negative regulation of programmed cell death | GO:0043069 | 58 | 0.027 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 4 | 0.027 | |
| atp catabolic process | GO:0006200 | 4 | 0.026 | |
| nucleic acid templated transcription | GO:0097659 | 181 | 0.026 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 7 | 0.026 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 4 | 0.026 | |
| cellular aromatic compound metabolic process | GO:0006725 | 295 | 0.026 | |
| transcription dna templated | GO:0006351 | 181 | 0.026 | |
| positive regulation of transport | GO:0051050 | 2 | 0.025 | |
| regulation of biological quality | GO:0065008 | 263 | 0.025 | |
| organic cyclic compound metabolic process | GO:1901360 | 301 | 0.024 | |
| tissue remodeling | GO:0048771 | 4 | 0.024 | |
| positive regulation of cell cycle | GO:0045787 | 3 | 0.024 | |
| regulation of metal ion transport | GO:0010959 | 4 | 0.024 | |
| organic acid metabolic process | GO:0006082 | 31 | 0.024 | |
| amine metabolic process | GO:0009308 | 2 | 0.024 | |
| regulation of cell death | GO:0010941 | 103 | 0.024 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.024 | |
| regulation of macromolecule metabolic process | GO:0060255 | 317 | 0.023 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 1 | 0.023 | |
| aromatic compound biosynthetic process | GO:0019438 | 217 | 0.023 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 4 | 0.023 | |
| regulation of cellular amine metabolic process | GO:0033238 | 0 | 0.023 | |
| apoptotic process | GO:0006915 | 116 | 0.023 | |
| cellular biosynthetic process | GO:0044249 | 286 | 0.023 | |
| cellular response to external stimulus | GO:0071496 | 2 | 0.022 | |
| maintenance of location | GO:0051235 | 4 | 0.022 | |
| oocyte maturation | GO:0001556 | 4 | 0.022 | |
| regulation of rna biosynthetic process | GO:2001141 | 213 | 0.022 | |
| regulation of meiotic cell cycle | GO:0051445 | 1 | 0.022 | |
| macromolecule biosynthetic process | GO:0009059 | 227 | 0.022 | |
| heterocycle biosynthetic process | GO:0018130 | 215 | 0.021 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 47 | 0.021 | |
| regulation of gene expression | GO:0010468 | 265 | 0.021 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 93 | 0.021 | |
| microtubule organizing center organization | GO:0031023 | 1 | 0.021 | |
| organelle organization | GO:0006996 | 227 | 0.021 | Yeast |
| regulation of mitochondrion organization | GO:0010821 | 1 | 0.021 | |
| regulation of proteolysis | GO:0030162 | 24 | 0.020 | |
| response to topologically incorrect protein | GO:0035966 | 2 | 0.020 | |
| regulation of apoptotic process | GO:0042981 | 98 | 0.020 | |
| regulation of cytoplasmic transport | GO:1903649 | 4 | 0.020 | |
| regulation of signaling | GO:0023051 | 235 | 0.020 | |
| centrosome organization | GO:0051297 | 1 | 0.020 | |
| negative regulation of protein phosphorylation | GO:0001933 | 4 | 0.020 | |
| negative regulation of cell death | GO:0060548 | 60 | 0.020 | |
| single organism metabolic process | GO:0044710 | 217 | 0.020 | |
| response to corticosteroid | GO:0031960 | 1 | 0.020 | |
| organic cyclic compound biosynthetic process | GO:1901362 | 223 | 0.019 | |
| female sex differentiation | GO:0046660 | 4 | 0.019 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 3 | 0.019 | |
| anion transport | GO:0006820 | 38 | 0.019 | |
| modification dependent protein catabolic process | GO:0019941 | 3 | 0.018 | |
| organic substance biosynthetic process | GO:1901576 | 289 | 0.018 | |
| negative regulation of catabolic process | GO:0009895 | 3 | 0.018 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.018 | |
| positive regulation of cellular catabolic process | GO:0031331 | 3 | 0.018 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 1 | 0.018 | |
| negative regulation of response to stimulus | GO:0048585 | 104 | 0.018 | |
| regulation of multicellular organismal process | GO:0051239 | 277 | 0.018 | |
| regulation of tube size | GO:0035150 | 2 | 0.017 | |
| regulation of calcium ion transport | GO:0051924 | 2 | 0.017 | |
| developmental growth | GO:0048589 | 166 | 0.017 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 4 | 0.017 | |
| system process | GO:0003008 | 185 | 0.017 | |
| regulation of nucleoside metabolic process | GO:0009118 | 2 | 0.017 | |
| oxidation reduction process | GO:0055114 | 41 | 0.017 | |
| nucleobase containing compound biosynthetic process | GO:0034654 | 205 | 0.017 | |
| compound eye development | GO:0048749 | 2 | 0.017 | |
| regulation of programmed cell death | GO:0043067 | 101 | 0.017 | |
| regulation of rna metabolic process | GO:0051252 | 224 | 0.016 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 4 | 0.016 | |
| negative regulation of metabolic process | GO:0009892 | 86 | 0.016 | |
| protein import | GO:0017038 | 3 | 0.016 | Yeast |
| regulation of intracellular protein transport | GO:0033157 | 3 | 0.016 | |
| protein secretion | GO:0009306 | 1 | 0.016 | |
| reproduction | GO:0000003 | 40 | 0.016 | Worm |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 2 | 0.016 | |
| response to chemical | GO:0042221 | 320 | 0.016 | |
| response to stress | GO:0006950 | 263 | 0.016 | |
| biosynthetic process | GO:0009058 | 294 | 0.016 | |
| cellular protein modification process | GO:0006464 | 100 | 0.016 | |
| regulation of protein catabolic process | GO:0042176 | 1 | 0.015 | |
| positive regulation of catabolic process | GO:0009896 | 4 | 0.015 | |
| single organism localization | GO:1902578 | 225 | 0.015 | Yeast |
| cellular amino acid metabolic process | GO:0006520 | 7 | 0.015 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 1 | 0.015 | |
| leukocyte proliferation | GO:0070661 | 1 | 0.015 | |
| generation of precursor metabolites and energy | GO:0006091 | 5 | 0.015 | |
| phosphorus metabolic process | GO:0006793 | 109 | 0.015 | |
| response to uv | GO:0009411 | 3 | 0.015 | |
| zymogen activation | GO:0031638 | 3 | 0.015 | |
| centrosome cycle | GO:0007098 | 1 | 0.015 | |
| cellular component morphogenesis | GO:0032989 | 336 | 0.015 | |
| cellular response to extracellular stimulus | GO:0031668 | 2 | 0.015 | |
| cell motility | GO:0048870 | 244 | 0.015 | |
| regionalization | GO:0003002 | 274 | 0.015 | |
| apoptotic process involved in morphogenesis | GO:0060561 | 2 | 0.014 | |
| regulation of transcription dna templated | GO:0006355 | 213 | 0.014 | |
| protein modification process | GO:0036211 | 100 | 0.014 | |
| negative regulation of cell communication | GO:0010648 | 96 | 0.014 | |
| organonitrogen compound metabolic process | GO:1901564 | 74 | 0.014 | |
| negative regulation of signaling | GO:0023057 | 96 | 0.014 | |
| regulation of protein localization to nucleus | GO:1900180 | 2 | 0.014 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 107 | 0.014 | |
| development of primary female sexual characteristics | GO:0046545 | 4 | 0.014 | |
| cellular response to unfolded protein | GO:0034620 | 2 | 0.014 | |
| macromolecule modification | GO:0043412 | 111 | 0.014 | |
| regulation of multicellular organismal development | GO:2000026 | 223 | 0.014 | |
| reactive oxygen species metabolic process | GO:0072593 | 6 | 0.014 | |
| single organism transport | GO:0044765 | 206 | 0.014 | Yeast |
| positive regulation of canonical wnt signaling pathway | GO:0090263 | 4 | 0.014 | |
| regulation of cellular macromolecule biosynthetic process | GO:2000112 | 222 | 0.014 | |
| chordate embryonic development | GO:0043009 | 271 | 0.014 | |
| cellular response to starvation | GO:0009267 | 1 | 0.013 | |
| cellular component assembly | GO:0022607 | 170 | 0.013 | |
| adult behavior | GO:0030534 | 2 | 0.013 | |
| fatty acid biosynthetic process | GO:0006633 | 4 | 0.013 | |
| sensory perception of pain | GO:0019233 | 1 | 0.013 | |
| regulation of macromolecule biosynthetic process | GO:0010556 | 225 | 0.013 | |
| regulation of protein import into nucleus | GO:0042306 | 2 | 0.013 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 59 | 0.013 | |
| tube closure | GO:0060606 | 1 | 0.013 | |
| regulation of molecular function | GO:0065009 | 70 | 0.013 | |
| muscle hypertrophy | GO:0014896 | 2 | 0.013 | |
| negative regulation of apoptotic process | GO:0043066 | 55 | 0.013 | |
| positive regulation of dna metabolic process | GO:0051054 | 1 | 0.012 | |
| cation transport | GO:0006812 | 81 | 0.012 | |
| regulation of nucleobase containing compound metabolic process | GO:0019219 | 250 | 0.012 | |
| phagocytosis | GO:0006909 | 3 | 0.012 | |
| regulation of membrane potential | GO:0042391 | 23 | 0.012 | |
| generation of neurons | GO:0048699 | 385 | 0.012 | |
| small molecule metabolic process | GO:0044281 | 77 | 0.012 | |
| positive regulation of proteolysis | GO:0045862 | 10 | 0.012 | |
| regulation of cytokine production | GO:0001817 | 3 | 0.012 | |
| cell surface receptor signaling pathway | GO:0007166 | 325 | 0.012 | |
| regulation of cellular protein metabolic process | GO:0032268 | 52 | 0.012 | |
| positive regulation of cellular process | GO:0048522 | 201 | 0.012 | |
| heart development | GO:0007507 | 313 | 0.012 | |
| regulation of cellular biosynthetic process | GO:0031326 | 245 | 0.012 | |
| cellular ketone metabolic process | GO:0042180 | 11 | 0.012 | |
| ovulation cycle | GO:0042698 | 2 | 0.012 | |
| mitotic cytokinesis | GO:0000281 | 3 | 0.012 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 4 | 0.011 | |
| regulation of protein targeting | GO:1903533 | 2 | 0.011 | |
| cellular response to topologically incorrect protein | GO:0035967 | 2 | 0.011 | |
| regulation of nucleotide catabolic process | GO:0030811 | 2 | 0.011 | |
| developmental programmed cell death | GO:0010623 | 4 | 0.011 | |
| oxoacid metabolic process | GO:0043436 | 31 | 0.011 | |
| transmembrane transport | GO:0055085 | 120 | 0.011 | Yeast |
| long chain fatty acid metabolic process | GO:0001676 | 1 | 0.011 | |
| b cell activation | GO:0042113 | 2 | 0.011 | |
| protein complex subunit organization | GO:0071822 | 46 | 0.011 | |
| embryonic organ development | GO:0048568 | 381 | 0.011 | |
| embryonic pattern specification | GO:0009880 | 44 | 0.011 | |
| stem cell differentiation | GO:0048863 | 117 | 0.011 | |
| positive regulation of metabolic process | GO:0009893 | 108 | 0.011 | |
| meiotic chromosome segregation | GO:0045132 | 3 | 0.011 | |
| female gonad development | GO:0008585 | 4 | 0.011 | |
| carbohydrate biosynthetic process | GO:0016051 | 1 | 0.011 | |
| homeostatic process | GO:0042592 | 142 | 0.011 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 76 | 0.011 | |
| negative regulation of signal transduction | GO:0009968 | 94 | 0.011 | |
| peptide transport | GO:0015833 | 1 | 0.011 | |
| regulation of endopeptidase activity | GO:0052548 | 23 | 0.011 | |
| negative regulation of defense response | GO:0031348 | 2 | 0.011 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 3 | 0.011 | |
| primary neural tube formation | GO:0014020 | 1 | 0.011 | |
| mitochondrion morphogenesis | GO:0070584 | 2 | 0.011 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.011 | |
| lipid storage | GO:0019915 | 1 | 0.011 | |
| regulation of organelle assembly | GO:1902115 | 4 | 0.011 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 2 | 0.011 | |
| proteolysis | GO:0006508 | 38 | 0.011 | |
| regulation of lipid transport | GO:0032368 | 4 | 0.011 | |
| spermatid development | GO:0007286 | 2 | 0.010 | |
| anterior posterior pattern specification | GO:0009952 | 152 | 0.010 | |
| negative regulation of gene expression | GO:0010629 | 65 | 0.010 | |
| intracellular signal transduction | GO:0035556 | 85 | 0.010 | |
| cellular response to radiation | GO:0071478 | 4 | 0.010 | |
| response to unfolded protein | GO:0006986 | 2 | 0.010 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 1 | 0.010 | |
| phagocytosis engulfment | GO:0006911 | 1 | 0.010 | |
| cellular lipid metabolic process | GO:0044255 | 36 | 0.010 | |
| cell proliferation | GO:0008283 | 80 | 0.010 | |
| single organism nuclear import | GO:1902593 | 3 | 0.010 | |
| regulation of protein metabolic process | GO:0051246 | 56 | 0.010 | |
| negative regulation of cellular metabolic process | GO:0031324 | 77 | 0.010 | |
| ion transmembrane transport | GO:0034220 | 91 | 0.010 | |
| organic anion transport | GO:0015711 | 15 | 0.010 | |
| sexual reproduction | GO:0019953 | 36 | 0.010 | |
| dna templated transcription initiation | GO:0006352 | 1 | 0.010 | |
| positive regulation of map kinase activity | GO:0043406 | 3 | 0.010 | |
| neural crest cell development | GO:0014032 | 62 | 0.010 | |
| negative regulation of kinase activity | GO:0033673 | 4 | 0.010 | |
| positive regulation of cell communication | GO:0010647 | 56 | 0.010 | |
