Danio rerio

0 known processes

psap

prosaposin

(Aliases: cb759,wu:fa14a06,wu:fb36e02,wu:fb58g07)

psap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.292
proteolysis involved in cellular protein catabolic processGO:005160330.258
agingGO:000756820.241
multicellular organismal metabolic processGO:004423620.232
cellular protein catabolic processGO:004425740.211
cellular response to extracellular stimulusGO:003166820.152
cellular response to external stimulusGO:007149620.151
establishment of localizationGO:00512342440.127
response to glucoseGO:000974930.116
cellular macromolecule metabolic processGO:00442603910.110
collagen metabolic processGO:003296320.110
response to hexoseGO:000974630.109
embryo development ending in birth or egg hatchingGO:00097922710.105
negative regulation of biological processGO:00485193040.105
Mouse
cellular response to chemical stimulusGO:00708871570.100
Mouse
positive regulation of transportGO:005105020.100
regulation of epithelial cell proliferationGO:005067830.096
organelle organizationGO:00069962270.093
response to ketoneGO:190165410.085
transportGO:00068102200.084
multicellular organismal macromolecule metabolic processGO:004425920.083
maintenance of locationGO:005123540.082
cellular response to starvationGO:000926710.081
response to carbohydrateGO:000974330.079
sensory organ developmentGO:00074233930.076
response to abiotic stimulusGO:00096281220.076
organic substance biosynthetic processGO:19015762890.070
response to alkaloidGO:004327920.068
response to monosaccharideGO:003428430.067
mitochondrion organizationGO:000700540.067
skeletal system developmentGO:00015011810.064
regulation of cell communicationGO:00106462320.061
Mouse
cellular response to nutrient levelsGO:003166920.060
regulation of hormone secretionGO:004688320.058
cellular response to hormone stimulusGO:0032870390.056
cellular component morphogenesisGO:00329893360.053
female gonad developmentGO:000858540.051
cellular response to organic substanceGO:00713101050.051
Mouse
blood vessel developmentGO:00015682460.050
response to corticosteroidGO:003196010.050
negative regulation of cellular processGO:00485232830.050
Mouse
cell deathGO:00082191210.049
Mouse
deathGO:00162651210.049
Mouse
response to chemicalGO:00422213200.049
Mouse
organic cyclic compound metabolic processGO:19013603010.048
regulation of biological qualityGO:00650082630.048
synaptic growth at neuromuscular junctionGO:005112420.047
positive regulation of cellular processGO:00485222010.046
Mouse
cellular response to oxygen levelsGO:007145310.046
single organism localizationGO:19025782250.044
negative regulation of epithelial cell proliferationGO:005068010.044
programmed cell deathGO:00125011190.044
cell projection morphogenesisGO:00488582440.044
extrinsic apoptotic signaling pathwayGO:009719130.043
regulation of cell deathGO:00109411030.043
Mouse
regulation of reproductive processGO:200024140.043
establishment of protein localization to organelleGO:007259440.043
gene expressionGO:00104672520.043
biosynthetic processGO:00090582940.042
autophagyGO:000691440.042
response to glucocorticoidGO:005138410.042
female sex differentiationGO:004666040.042
cellular component assemblyGO:00226071700.041
single organism metabolic processGO:00447102170.041
Mouse
generation of neuronsGO:00486993850.039
lipid storageGO:001991510.039
multicellular organism growthGO:003526440.039
cellular ketone metabolic processGO:0042180110.039
cellular response to endogenous stimulusGO:0071495680.038
modification dependent protein catabolic processGO:001994130.038
regulation of cell activationGO:005086510.038
growthGO:00400071740.037
Mouse
positive regulation of protein complex assemblyGO:003133420.037
adult behaviorGO:003053420.037
response to other organismGO:0051707970.036
eye developmentGO:00016542770.036
developmental growthGO:00485891660.036
Mouse
negative regulation of protein phosphorylationGO:000193340.036
response to drugGO:004249330.036
response to mechanical stimulusGO:0009612240.035
stem cell divisionGO:001714510.035
establishment of localization in cellGO:0051649770.035
morphogenesis of an epitheliumGO:00020093330.035
protein metabolic processGO:00195381830.035
neurological system processGO:0050877620.035
skeletal system morphogenesisGO:00487051020.035
single organism organelle organizationGO:19025891990.035
response to organic cyclic compoundGO:0014070510.034
regulation of macromolecule metabolic processGO:00602553170.033
cellular response to decreased oxygen levelsGO:003629410.033
response to external stimulusGO:00096052640.033
protein localization to nucleusGO:003450430.033
synaptic vesicle endocytosisGO:004848810.033
response to organic substanceGO:00100331530.033
Mouse
nuclear importGO:005117030.032
nucleobase containing compound metabolic processGO:00061392740.032
organic cyclic compound biosynthetic processGO:19013622230.032
negative regulation of signalingGO:0023057960.032
cellular localizationGO:0051641970.031
leukocyte mediated cytotoxicityGO:000190910.031
reproductionGO:0000003400.031
lymphocyte proliferationGO:004665110.031
fertilizationGO:000956630.030
cell morphogenesisGO:00009022890.030
nitrogen compound metabolic processGO:00068073190.030
regulation of protein complex assemblyGO:004325430.030
multi organism processGO:00517041340.030
nuclear transportGO:005116940.029
nucleocytoplasmic transportGO:000691340.029
protein import into nucleusGO:000660630.029
cell part morphogenesisGO:00329902460.029
system processGO:00030081850.029
camera type eye developmentGO:00430102220.029
regulation of multicellular organism growthGO:004001440.028
regulation of protein import into nucleusGO:004230620.028
cartilage developmentGO:0051216960.028
cellular protein metabolic processGO:00442671290.028
cell projection organizationGO:00300302840.028
regulation of metal ion transportGO:001095940.028
regulation of membrane potentialGO:0042391230.028
rna transportGO:005065820.028
angiogenesisGO:00015251580.028
negative regulation of cell communicationGO:0010648960.028
regulation of stem cell differentiationGO:200073640.028
negative regulation of signal transductionGO:0009968940.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
protein targeting to nucleusGO:004474430.027
gland developmentGO:00487321430.027
Mouse
positive regulation of epithelial cell proliferationGO:005067910.027
response to hormoneGO:0009725480.027
synaptic vesicle recyclingGO:003646510.027
mitochondrial transportGO:000683920.027
rna localizationGO:000640340.026
cellular response to hypoxiaGO:007145610.026
gtp metabolic processGO:004603940.026
development of primary female sexual characteristicsGO:004654540.026
axon developmentGO:00615641660.026
appendage morphogenesisGO:0035107560.026
b cell activationGO:004211320.026
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.026
response to nutrientGO:000758430.026
positive regulation of i kappab kinase nf kappab signalingGO:004312330.025
ubiquitin dependent protein catabolic processGO:000651130.025
small molecule metabolic processGO:0044281770.025
positive regulation of cell cycleGO:004578730.025
regulation of protein targetingGO:190353320.025
organic substance transportGO:0071702580.025
apoptotic process involved in developmentGO:190274220.025
hormone secretionGO:004687920.025
vasculature developmentGO:00019442780.025
organonitrogen compound metabolic processGO:1901564740.025
response to stressGO:00069502630.025
Mouse
regulation of protein catabolic processGO:004217610.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
membrane invaginationGO:001032410.024
regulation of cellular component organizationGO:0051128860.024
organic acid metabolic processGO:0006082310.024
response to woundingGO:00096111160.024
epithelial cell differentiationGO:00308551160.024
Mouse
guanosine containing compound metabolic processGO:190106840.024
regulation of cellular amino acid metabolic processGO:000652100.024
response to endogenous stimulusGO:0009719830.024
iron ion homeostasisGO:005507240.024
cytokinesisGO:000091030.024
regulation of synapse organizationGO:005080730.024
regenerationGO:0031099910.024
amine metabolic processGO:000930820.024
single organism membrane organizationGO:0044802200.024
dopamine metabolic processGO:004241720.023
proteasomal protein catabolic processGO:001049820.023
cellular biosynthetic processGO:00442492860.023
glial cell migrationGO:000834730.023
i kappab kinase nf kappab signalingGO:000724940.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
axon ensheathment in central nervous systemGO:003229120.022
embryonic skeletal system morphogenesisGO:0048704930.022
positive regulation of biological processGO:00485182530.022
Mouse
membrane organizationGO:0061024210.022
negative regulation of myeloid cell differentiationGO:004563810.022
blood circulationGO:0008015870.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
cellular amine metabolic processGO:004410620.022
brain developmentGO:00074202930.022
immune system processGO:00023762410.022
secondary metabolic processGO:001974830.022
regulation of nucleocytoplasmic transportGO:004682220.022
apoptotic processGO:00069151160.022
regulation of blood pressureGO:000821710.022
sensory system developmentGO:0048880760.021
embryonic organ morphogenesisGO:00485622740.021
regulation of establishment of protein localizationGO:007020140.021
stem cell maintenanceGO:001982740.021
phagocytosisGO:000690930.021
regulation of reactive oxygen species metabolic processGO:200037720.021
cellular amino acid metabolic processGO:000652070.021
nucleic acid transportGO:005065720.021
tissue remodelingGO:004877140.021
golgi vesicle transportGO:004819330.021
cellular nitrogen compound metabolic processGO:00346412900.021
endosomal transportGO:001619720.021
protein importGO:001703830.021
neuron developmentGO:00486662620.021
localization of cellGO:00516742440.021
regulation of i kappab kinase nf kappab signalingGO:004312240.020
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.020
neuron differentiationGO:00301823530.020
regulation of blood vessel sizeGO:005088020.020
establishment of synaptic vesicle localizationGO:009748010.020
single organism transportGO:00447652060.020
establishment of rna localizationGO:005123630.020
hormone transportGO:000991420.020
mesenchymal cell differentiationGO:0048762870.020
gtp catabolic processGO:000618420.020
wound healingGO:0042060900.020
single organism nuclear importGO:190259330.020
positive regulation of gliogenesisGO:001401520.019
regulation of programmed cell deathGO:00430671010.019
proteolysisGO:0006508380.019
somatic stem cell maintenanceGO:003501910.019
positive regulation of cellular component biogenesisGO:004408930.019
head developmentGO:00603223030.019
regulation of cytoplasmic transportGO:190364940.019
transcription dna templatedGO:00063511810.019
nerve developmentGO:0021675450.019
cell surface receptor signaling pathwayGO:00071663250.019
Mouse
positive regulation of cellular catabolic processGO:003133130.018
signal transduction in absence of ligandGO:003803410.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
positive regulation of catabolic processGO:000989640.018
positive regulation of immune effector processGO:000269930.018
organonitrogen compound biosynthetic processGO:1901566470.018
lipid catabolic processGO:001604240.018
erythrocyte homeostasisGO:0034101550.018
cellular transition metal ion homeostasisGO:004691630.018
regulation of apoptotic processGO:0042981980.018
response to antibioticGO:004667710.018
aromatic compound biosynthetic processGO:00194382170.018
regulation of protein transportGO:005122330.018
tube morphogenesisGO:00352393490.018
hepaticobiliary system developmentGO:0061008980.018
regulation of growthGO:0040008420.018
cellular response to stressGO:0033554620.018
Mouse
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
response to decreased oxygen levelsGO:0036293250.017
embryonic skeletal system developmentGO:0048706970.017
oxoacid metabolic processGO:0043436310.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
regulation of circadian rhythmGO:004275240.017
negative regulation of response to stimulusGO:00485851040.017
Mouse
signal transductionGO:00071654550.017
Mouse
negative regulation of protein kinase activityGO:000646940.017
modification dependent macromolecule catabolic processGO:004363230.017
negative regulation of cell deathGO:0060548600.017
Mouse
negative regulation of kinase activityGO:003367340.017
peptidyl serine modificationGO:001820920.017
response to vitaminGO:003327330.017
cellular response to radiationGO:007147840.017
neurotransmitter transportGO:000683620.017
erk1 and erk2 cascadeGO:007037140.017
appendage developmentGO:0048736800.017
synaptic vesicle localizationGO:009747910.017
carboxylic acid metabolic processGO:0019752220.017
regulation of cellular protein catabolic processGO:190336210.017
regulation of wound healingGO:006104120.017
fin developmentGO:0033333770.016
meiotic nuclear divisionGO:000712640.016
regulation of signalingGO:00230512350.016
Mouse
reactive oxygen species biosynthetic processGO:190340910.016
chordate embryonic developmentGO:00430092710.016
actin polymerization or depolymerizationGO:000815420.016
primary neural tube formationGO:001402010.016
cellular macromolecule localizationGO:0070727210.016
regulation of synapse assemblyGO:005196330.016
regulation of nitrogen compound metabolic processGO:00511712510.016
amino acid transportGO:000686520.016
meiotic cell cycle processGO:190304630.016
positive regulation of secretion by cellGO:190353210.016
membrane fusionGO:006102520.016
mononuclear cell proliferationGO:003294310.016
transcription from rna polymerase ii promoterGO:0006366800.015
neuronal action potentialGO:0019228180.015
camera type eye morphogenesisGO:00485931080.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
vacuolar transportGO:000703420.015
regulation of tube sizeGO:003515020.015
macromolecule catabolic processGO:0009057150.015
long chain fatty acid metabolic processGO:000167610.015
negative regulation of stem cell differentiationGO:200073720.015
stem cell proliferationGO:007208940.015
regulation of dendrite developmentGO:005077330.015
catechol containing compound biosynthetic processGO:000971320.015
macromolecule modificationGO:00434121110.015
compound eye developmentGO:004874920.015
regulation of cell shapeGO:000836010.015
epithelial tube morphogenesisGO:00605621480.015
endosome to lysosome transportGO:000833310.015
internal protein amino acid acetylationGO:000647520.015
hatching gland developmentGO:004878530.015
rna metabolic processGO:00160702190.015
interaction with hostGO:005170140.015
negative regulation of mapk cascadeGO:004340940.015
regulation of cytokine productionGO:000181730.015
nucleobase containing compound biosynthetic processGO:00346542050.015
regulation of epithelial to mesenchymal transitionGO:001071730.015
regulation of cellular amine metabolic processGO:003323800.015
macromolecule localizationGO:0033036540.015
alpha amino acid metabolic processGO:190160530.015
embryonic viscerocranium morphogenesisGO:0048703520.015
protein acylationGO:004354330.015
neuron projection developmentGO:00311751800.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
cellular catabolic processGO:0044248270.014
heterocycle metabolic processGO:00464832900.014
synaptic vesicle transportGO:004848910.014
organic acid catabolic processGO:001605430.014
skeletal muscle organ developmentGO:0060538780.014
protein localization to plasma membraneGO:007265910.014
rna biosynthetic processGO:00327741810.014
cellular aromatic compound metabolic processGO:00067252950.014
leukocyte proliferationGO:007066110.014
regulation of meiotic cell cycleGO:005144510.014
response to steroid hormoneGO:0048545350.014
positive regulation of cell killingGO:003134320.014
nucleic acid metabolic processGO:00903042440.014
regionalizationGO:00030022740.014
regulation of developmental processGO:00507932470.014
regulation of synaptic plasticityGO:004816710.014
reactive nitrogen species metabolic processGO:200105700.014
regulation of glial cell differentiationGO:004568540.014
skeletal muscle tissue developmentGO:0007519670.014
microtubule organizing center organizationGO:003102310.014
regulation of cellular metabolic processGO:00313233200.014
Mouse
establishment of epithelial cell polarityGO:009016220.013
calcium ion importGO:007050940.013
multi organism cellular processGO:004476420.013
negative regulation of protein complex assemblyGO:003133310.013
response to oxygen levelsGO:0070482250.013
regulation of multicellular organismal processGO:00512392770.013
peptide transportGO:001583310.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
regulation of gene expressionGO:00104682650.013
positive regulation of cellular metabolic processGO:0031325940.013
Mouse
transmission of nerve impulseGO:0019226190.013
cellular response to steroid hormone stimulusGO:0071383310.013
single organism cellular localizationGO:1902580460.013
tube closureGO:006060610.013
interspecies interaction between organismsGO:004441940.013
regulation of inflammatory responseGO:005072720.013
neuron projection morphogenesisGO:00488121610.013
mesenchyme developmentGO:00604851270.013
central nervous system myelin formationGO:003228910.013
cell proliferationGO:0008283800.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
regulation of rna metabolic processGO:00512522240.012
regulation of bindingGO:005109830.012
cellular component biogenesisGO:00440851780.012
axonogenesisGO:00074091520.012
lateral line system developmentGO:0048925760.012
intracellular transportGO:0046907320.012
cellular component assembly involved in morphogenesisGO:00109271070.012
carboxylic acid catabolic processGO:004639530.012
retina morphogenesis in camera type eyeGO:0060042790.012
action potentialGO:0001508190.012
cell killingGO:000190620.012
nitrogen compound transportGO:0071705230.012
circulatory system processGO:0003013870.012
regulation of metabolic processGO:00192223590.012
Mouse
lateral inhibitionGO:004633110.012
b cell differentiationGO:003018310.012
dorsal ventral pattern formationGO:00099531250.012
pole plasm assemblyGO:000731540.012
regulation of cellular ketone metabolic processGO:001056570.012
bone remodelingGO:004684920.012
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.012
anterior posterior pattern specificationGO:00099521520.012
regulation of protein localization to nucleusGO:190018020.012
regulation of transcription dna templatedGO:00063552130.012
peptidyl lysine acetylationGO:001839420.012
organelle fusionGO:004828430.012
myelin assemblyGO:003228810.012
regulation of intracellular protein transportGO:003315730.012
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.012
gamete generationGO:0007276330.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
cellular component disassemblyGO:002241110.012
tissue regenerationGO:0042246740.012
forebrain developmentGO:0030900960.012
phenol containing compound biosynthetic processGO:004618940.012
response to lipidGO:0033993600.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
alcohol biosynthetic processGO:004616520.012
regulation of nervous system developmentGO:0051960900.012
developmental programmed cell deathGO:001062340.012
cellular component movementGO:00069283350.012
guanosine containing compound catabolic processGO:190106920.012
multicellular organismal signalingGO:0035637220.012
regulation of carbohydrate metabolic processGO:000610940.012
organic substance catabolic processGO:1901575280.012
small molecule catabolic processGO:004428230.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
protein homooligomerizationGO:005126030.011
b cell mediated immunityGO:001972430.011
catecholamine biosynthetic processGO:004242320.011
negative regulation of map kinase activityGO:004340720.011
adaptive immune responseGO:000225050.011
regulation of multicellular organismal developmentGO:20000262230.011
dna templated transcription elongationGO:000635430.011
regulation of tissue remodelingGO:003410320.011
digestive tract morphogenesisGO:00485462310.011
negative regulation of response to dna damage stimulusGO:200102130.011
regulation of nucleotide catabolic processGO:003081120.011
embryonic organ developmentGO:00485683810.011
odontogenesis of dentin containing toothGO:004247510.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
muscle structure developmentGO:00610611960.011
lysosomal transportGO:000704120.011
cell cycle g1 s phase transitionGO:004484310.011
cell cell recognitionGO:000998810.011
positive regulation of biosynthetic processGO:0009891680.011
cognitionGO:005089010.011
protein polymerizationGO:005125840.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
negative regulation of macromolecule metabolic processGO:0010605760.011
response to xenobiotic stimulusGO:0009410450.011
glucose homeostasisGO:004259310.011
nuclear exportGO:005116810.011
positive regulation of cytoskeleton organizationGO:005149530.011
response to external biotic stimulusGO:0043207970.011
water homeostasisGO:003010440.011
cell growthGO:0016049570.011
positive regulation of protein polymerizationGO:003227320.011
regulation of cellular biosynthetic processGO:00313262450.011
germ line stem cell divisionGO:004207810.011
catechol containing compound metabolic processGO:000971220.011
zymogen activationGO:003163830.011
cellular macromolecule biosynthetic processGO:00346452240.011
positive regulation of rna biosynthetic processGO:1902680570.011
oxidation reduction processGO:0055114410.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
cellular response to biotic stimulusGO:007121630.011
mitotic dna integrity checkpointGO:004477440.010
regulation of sodium ion transportGO:000202820.010
protein complex biogenesisGO:0070271300.010
osteoclast differentiationGO:003031610.010
regulation of erk1 and erk2 cascadeGO:007037240.010
trabecula morphogenesisGO:006138320.010
regulation of anatomical structure morphogenesisGO:00226031300.010
g1 s transition of mitotic cell cycleGO:000008210.010
response to acid chemicalGO:0001101170.010
positive regulation of metabolic processGO:00098931080.010
Mouse
positive regulation of nucleoside metabolic processGO:004597910.010
intracellular signal transductionGO:0035556850.010
Mouse
protein complex localizationGO:003150310.010
regulation of signal transductionGO:00099662250.010
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.010
multi organism reproductive processGO:0044703360.010
positive regulation of cell activationGO:005086710.010
reproductive processGO:0022414400.010
Mouse
regulation of jun kinase activityGO:004350630.010
sensory perception of chemical stimulusGO:000760630.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
neuroblast proliferationGO:000740520.010
cytokinetic processGO:003250620.010
negative regulation of dna metabolic processGO:005105340.010
protein acetylationGO:000647320.010
internal peptidyl lysine acetylationGO:001839320.010
eye morphogenesisGO:00485921440.010
cytoskeleton dependent cytokinesisGO:006164030.010
endocytosisGO:0006897160.010
protein localizationGO:0008104400.010

psap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.136
Human
disease of metabolismDOID:001466700.136
Human
lysosomal storage diseaseDOID:321100.136
Human
disease of anatomical entityDOID:700.056
Human
immune system diseaseDOID:291400.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
nervous system diseaseDOID:86300.010
Human