Danio rerio

15 known processes

igfbp2b

insulin-like growth factor binding protein 2b

(Aliases: si:ch211-2k18.3,igfbp2a)

igfbp2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.161
Zebrafish
regulation of signalingGO:00230512350.102
Zebrafish
signal transductionGO:00071654550.096
Zebrafish Rat
negative regulation of biological processGO:00485193040.094
regulation of signal transductionGO:00099662250.093
Zebrafish
regulation of cellular ketone metabolic processGO:001056570.090
regulation of response to stimulusGO:00485832690.088
Zebrafish
intracellular signal transductionGO:0035556850.087
cellular ketone metabolic processGO:0042180110.084
positive regulation of cellular amine metabolic processGO:003324000.076
cellular amine metabolic processGO:004410620.076
carboxylic acid metabolic processGO:0019752220.071
oxoacid metabolic processGO:0043436310.070
regulation of protein kinase b signalingGO:005189680.069
negative regulation of response to stimulusGO:00485851040.067
Zebrafish
response to monosaccharideGO:003428430.065
regulation of cellular amine metabolic processGO:003323800.063
mitochondrion organizationGO:000700540.063
response to external stimulusGO:00096052640.058
Rat
regulation of gene expressionGO:00104682650.057
Zebrafish
pancreas developmentGO:0031016840.056
skeletal system developmentGO:00015011810.056
Zebrafish
embryonic organ developmentGO:00485683810.056
Zebrafish
protein metabolic processGO:00195381830.056
organic acid metabolic processGO:0006082310.056
leukocyte proliferationGO:007066110.055
Human
regulation of cell communicationGO:00106462320.053
Zebrafish
response to chemicalGO:00422213200.053
Rat
protein kinase b signalingGO:004349190.052
mononuclear cell proliferationGO:003294310.052
Human
regulation of protein catabolic processGO:004217610.051
positive regulation of cell activationGO:005086710.051
Human
response to hexoseGO:000974630.051
central nervous system developmentGO:00074173870.050
transcription from rna polymerase ii promoterGO:0006366800.050
lipid storageGO:001991510.049
amine metabolic processGO:000930820.049
response to nutrientGO:000758430.049
Rat
positive regulation of cellular amino acid metabolic processGO:004576400.047
cellular nitrogen compound metabolic processGO:00346412900.046
Zebrafish
cellular protein metabolic processGO:00442671290.045
maintenance of locationGO:005123540.044
nitrogen compound metabolic processGO:00068073190.044
Zebrafish
response to glucoseGO:000974930.043
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.043
cellular response to external stimulusGO:007149620.043
segmentationGO:0035282970.042
regulation of biological qualityGO:00650082630.040
cellular amino acid metabolic processGO:000652070.040
regulation of inflammatory responseGO:005072720.040
larval developmentGO:000216420.039
response to carbohydrateGO:000974330.039
embryonic organ morphogenesisGO:00485622740.039
Zebrafish
agingGO:000756820.039
Rat
exocrine pancreas developmentGO:0031017280.038
phosphate containing compound metabolic processGO:00067961080.038
regulation of metal ion transportGO:001095940.038
cell part morphogenesisGO:00329902460.038
head developmentGO:00603223030.037
regulation of reproductive processGO:200024140.037
response to stressGO:00069502630.037
Zebrafish
renal system developmentGO:0072001940.037
carbohydrate derivative metabolic processGO:1901135610.037
kidney developmentGO:0001822920.036
response to lipidGO:0033993600.036
Rat
regulation of dendrite developmentGO:005077330.036
regulation of cellular amino acid metabolic processGO:000652100.036
small molecule metabolic processGO:0044281770.036
digestive system developmentGO:00551232890.035
lymphocyte proliferationGO:004665110.035
Human
hepaticobiliary system developmentGO:0061008980.035
alpha amino acid metabolic processGO:190160530.035
brain developmentGO:00074202930.035
heart developmentGO:00075073130.035
Zebrafish
response to corticosteroidGO:003196010.034
Rat
establishment of localizationGO:00512342440.034
organonitrogen compound metabolic processGO:1901564740.034
positive regulation of cell cycleGO:004578730.034
gland developmentGO:00487321430.034
neuron differentiationGO:00301823530.033
regulation of establishment of protein localizationGO:007020140.033
response to woundingGO:00096111160.033
pigment granule transportGO:0051904190.032
embryo development ending in birth or egg hatchingGO:00097922710.031
Zebrafish
cellular component biogenesisGO:00440851780.031
energy reserve metabolic processGO:000611220.031
gastrulationGO:00073692080.031
cellular protein modification processGO:00064641000.031
cellular response to nutrient levelsGO:003166920.031
regulation of peptidyl tyrosine phosphorylationGO:005073010.031
positive regulation of protein kinase b signalingGO:005189710.031
regulation of extrinsic apoptotic signaling pathwayGO:200123630.031
biosynthetic processGO:00090582940.030
Zebrafish
positive regulation of cellular processGO:00485222010.030
Human
gene expressionGO:00104672520.030
muscle structure developmentGO:00610611960.030
aromatic compound biosynthetic processGO:00194382170.030
phagocytosisGO:000690930.030
positive regulation of transportGO:005105020.029
positive regulation of cellular carbohydrate metabolic processGO:001067610.029
somitogenesisGO:0001756870.029
cognitionGO:005089010.028
peptide transportGO:001583310.028
carbohydrate derivative biosynthetic processGO:1901137430.028
multicellular organism growthGO:003526440.028
Zebrafish
response to alkaloidGO:004327920.027
negative regulation of signal transductionGO:0009968940.027
Zebrafish
pronephros developmentGO:0048793690.027
cellular pigmentationGO:0033059300.027
negative regulation of cell communicationGO:0010648960.027
Zebrafish
protein stabilizationGO:005082120.027
negative regulation of cellular processGO:00485232830.027
Zebrafish
growthGO:00400071740.026
glucose homeostasisGO:004259310.026
single organism biosynthetic processGO:0044711710.026
cellular response to starvationGO:000926710.026
organelle organizationGO:00069962270.026
cellular macromolecule metabolic processGO:00442603910.025
Zebrafish
vasculature developmentGO:00019442780.025
Zebrafish
heterocycle biosynthetic processGO:00181302150.025
cellular protein catabolic processGO:004425740.025
cellular response to lipopolysaccharideGO:007122230.025
cellular response to light stimulusGO:007148240.025
neuron neuron synaptic transmissionGO:000727010.025
generation of neuronsGO:00486993850.025
regulation of intracellular signal transductionGO:1902531570.024
regulation of cell activationGO:005086510.024
Human
regulation of macromolecule metabolic processGO:00602553170.024
Zebrafish
nuclear importGO:005117030.024
cell morphogenesis involved in neuron differentiationGO:00486671630.024
single organism organelle organizationGO:19025891990.024
multi organism reproductive processGO:0044703360.024
Rat
positive regulation of macromolecule metabolic processGO:0010604930.024
single organism metabolic processGO:00447102170.024
regulation of multicellular organism growthGO:004001440.024
Zebrafish
single organism localizationGO:19025782250.024
neuron developmentGO:00486662620.023
intracellular receptor signaling pathwayGO:0030522300.023
extrinsic apoptotic signaling pathwayGO:009719130.023
cellular component morphogenesisGO:00329893360.023
cellular nitrogen compound biosynthetic processGO:00442712180.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
urogenital system developmentGO:0001655970.023
cell substrate adhesionGO:003158940.023
cellular response to extracellular stimulusGO:003166820.023
regenerationGO:0031099910.022
ubiquitin dependent protein catabolic processGO:000651130.022
regulation of skeletal muscle tissue developmentGO:004864140.022
regulation of hormone secretionGO:004688320.022
nucleic acid metabolic processGO:00903042440.022
Zebrafish
cell migrationGO:00164772370.022
positive regulation of cytokine productionGO:000181920.022
regulation of carbohydrate metabolic processGO:000610940.022
macromolecule biosynthetic processGO:00090592270.022
Zebrafish
modification dependent protein catabolic processGO:001994130.022
liver developmentGO:0001889960.022
somatic muscle developmentGO:000752540.022
modification dependent macromolecule catabolic processGO:004363230.021
oocyte maturationGO:000155640.021
lipid metabolic processGO:0006629520.021
epithelial tube morphogenesisGO:00605621480.021
negative regulation of intracellular signal transductionGO:1902532220.021
digestive tract developmentGO:00485652650.021
cellular aromatic compound metabolic processGO:00067252950.021
Zebrafish
macromolecule modificationGO:00434121110.020
cell motilityGO:00488702440.020
cellular carbohydrate metabolic processGO:004426240.020
long chain fatty acid metabolic processGO:000167610.020
somite developmentGO:0061053960.020
response to vitaminGO:003327330.020
guanosine containing compound catabolic processGO:190106920.020
system processGO:00030081850.020
regulation of cytokine productionGO:000181730.020
regulation of nitrogen compound metabolic processGO:00511712510.020
Zebrafish
single organism nuclear importGO:190259330.020
skeletal system morphogenesisGO:00487051020.020
camera type eye developmentGO:00430102220.020
positive regulation of immune effector processGO:000269930.020
negative regulation of protein transportGO:005122430.020
proteasomal protein catabolic processGO:001049820.020
gtp metabolic processGO:004603940.020
regulation of jak stat cascadeGO:004642530.019
pigment granule localizationGO:0051875250.019
establishment of protein localization to organelleGO:007259440.019
response to drugGO:004249330.019
Rat
embryonic skeletal system developmentGO:0048706970.019
regulation of circadian rhythmGO:004275240.019
synaptic transmission cholinergicGO:000727140.019
cilium morphogenesisGO:0060271850.019
neural crest cell migrationGO:0001755420.019
programmed cell deathGO:00125011190.019
transportGO:00068102200.018
melanosome transportGO:0032402190.018
protein modification processGO:00362111000.018
regulation of calcium ion transportGO:005192420.018
cellular response to molecule of bacterial originGO:007121930.018
hormone transportGO:000991420.018
cell surface receptor signaling pathwayGO:00071663250.018
Zebrafish
water homeostasisGO:003010440.018
cellular response to organic substanceGO:00713101050.018
Rat
heterocycle metabolic processGO:00464832900.018
Zebrafish
gastrulation with mouth forming secondGO:0001702440.018
response to other organismGO:0051707970.018
response to ketoneGO:190165410.018
fertilizationGO:000956630.018
retina development in camera type eyeGO:00600411460.017
positive regulation of cellular catabolic processGO:003133130.017
hindbrain developmentGO:0030902910.017
response to glucocorticoidGO:005138410.017
Rat
cellular response to radiationGO:007147840.017
negative regulation of protein phosphorylationGO:000193340.017
positive regulation of carbohydrate metabolic processGO:004591310.017
regulation of cell cycleGO:0051726520.017
anterior posterior pattern specificationGO:00099521520.017
reactive nitrogen species metabolic processGO:200105700.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
organic substance biosynthetic processGO:19015762890.017
Zebrafish
deathGO:00162651210.017
regulation of cytoplasmic transportGO:190364940.017
hormone secretionGO:004687920.017
nucleocytoplasmic transportGO:000691340.017
b cell activationGO:004211320.017
response to external biotic stimulusGO:0043207970.017
cellular response to chemical stimulusGO:00708871570.017
Rat
rna metabolic processGO:00160702190.017
carbohydrate biosynthetic processGO:001605110.017
negative regulation of defense responseGO:003134820.017
superoxide metabolic processGO:000680120.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
establishment of pigment granule localizationGO:0051905220.016
phosphorus metabolic processGO:00067931090.016
eye morphogenesisGO:00485921440.016
neural crest cell developmentGO:0014032620.016
regulation of primary metabolic processGO:00800903110.016
Zebrafish
regulation of cellular carbohydrate metabolic processGO:001067540.016
melanosome localizationGO:0032400210.016
positive regulation of catabolic processGO:000989640.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
negative regulation of secretionGO:005104820.016
regulation of protein transportGO:005122330.016
positive regulation of lipid metabolic processGO:004583410.016
nuclear transportGO:005116940.016
carbohydrate homeostasisGO:003350010.016
pigmentationGO:0043473850.016
negative regulation of protein kinase b signalingGO:005189820.016
positive regulation of response to stimulusGO:0048584800.016
positive regulation of biological processGO:00485182530.016
Human
regulation of dendrite morphogenesisGO:004881430.016
negative regulation of mapk cascadeGO:004340940.016
protein importGO:001703830.016
sensory organ morphogenesisGO:00905962000.016
Zebrafish
ameboidal type cell migrationGO:00016671430.016
response to steroid hormoneGO:0048545350.016
Rat
regulation of purine nucleotide catabolic processGO:003312120.015
pyruvate metabolic processGO:000609010.015
regulation of blood vessel sizeGO:005088020.015
regulation of protein ubiquitinationGO:003139630.015
regulation of muscle contractionGO:000693730.015
fatty acid biosynthetic processGO:000663340.015
multi organism processGO:00517041340.015
Rat
eye developmentGO:00016542770.015
antimicrobial humoral responseGO:001973020.015
autophagyGO:000691440.015
stem cell maintenanceGO:001982740.015
single fertilizationGO:000733830.015
tube morphogenesisGO:00352393490.015
adult behaviorGO:003053420.015
multicellular organismal metabolic processGO:004423620.015
ear developmentGO:00435831270.015
Zebrafish
protein acetylationGO:000647320.015
cellular macromolecule biosynthetic processGO:00346452240.015
Zebrafish
positive regulation of gtp catabolic processGO:003312610.015
notochord developmentGO:0030903540.015
positive regulation of cell divisionGO:005178120.015
regulation of multicellular organismal processGO:00512392770.015
Zebrafish
small molecule catabolic processGO:004428230.015
protein localization to nucleusGO:003450430.015
positive regulation of neural precursor cell proliferationGO:200017910.015
sensory organ developmentGO:00074233930.015
Zebrafish
internal peptidyl lysine acetylationGO:001839320.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
embryonic skeletal system morphogenesisGO:0048704930.015
organic cyclic compound metabolic processGO:19013603010.015
Zebrafish
symbiosis encompassing mutualism through parasitismGO:004440340.014
blood vessel developmentGO:00015682460.014
Zebrafish
regulation of erk1 and erk2 cascadeGO:007037240.014
post embryonic organ developmentGO:004856940.014
meiotic cell cycle processGO:190304630.014
mesenchyme developmentGO:00604851270.014
regulation of neural precursor cell proliferationGO:200017730.014
epiboly involved in gastrulation with mouth forming secondGO:0055113350.014
stem cell proliferationGO:007208940.014
regulation of carbohydrate biosynthetic processGO:004325510.014
protein targeting to nucleusGO:004474430.014
cellular component assemblyGO:00226071700.014
response to bacteriumGO:0009617580.014
axonogenesisGO:00074091520.014
regulation of metabolic processGO:00192223590.014
Zebrafish
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
Zebrafish
fin regenerationGO:0031101510.014
regulation of protein complex assemblyGO:004325430.014
protein dephosphorylationGO:000647030.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
protein import into nucleusGO:000660630.014
cation transmembrane transportGO:0098655650.014
guanosine containing compound metabolic processGO:190106840.014
hemopoiesisGO:00300971830.014
negative regulation of mitosisGO:004583930.014
positive regulation of rna biosynthetic processGO:1902680570.014
sleepGO:003043110.014
gtp catabolic processGO:000618420.014
sensory system developmentGO:0048880760.014
regulation of nucleotide catabolic processGO:003081120.014
negative regulation of cell deathGO:0060548600.014
peptidyl lysine acetylationGO:001839420.014
regulation of reactive oxygen species metabolic processGO:200037720.014
positive regulation of cell killingGO:003134320.014
developmental growthGO:00485891660.013
regulation of stem cell proliferationGO:007209120.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
cellular response to oxygen levelsGO:007145310.013
neuron projection developmentGO:00311751800.013
inner ear developmentGO:00488391260.013
Zebrafish
establishment of melanosome localizationGO:0032401190.013
organic cyclic compound biosynthetic processGO:19013622230.013
skeletal muscle tissue developmentGO:0007519670.013
connective tissue developmentGO:0061448990.013
localization of cellGO:00516742440.013
inositol lipid mediated signalingGO:004801720.013
stem cell developmentGO:0048864820.013
regulation of gtpase activityGO:004308720.013
positive regulation of gtpase activityGO:004354710.013
toll like receptor signaling pathwayGO:000222440.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
morphogenesis of an epithelial sheetGO:0002011490.013
positive regulation of metabolic processGO:00098931080.013
regulation of anatomical structure morphogenesisGO:00226031300.013
regulation of programmed cell deathGO:00430671010.013
muscle tissue developmentGO:00605371100.013
positive regulation of map kinase activityGO:004340630.013
regulation of nucleoside metabolic processGO:000911820.013
single organism transportGO:00447652060.013
response to lipopolysaccharideGO:0032496130.013
apoptotic processGO:00069151160.013
positive regulation of rna metabolic processGO:0051254590.013
cellular biosynthetic processGO:00442492860.013
Zebrafish
positive regulation of cellular protein metabolic processGO:0032270220.013
muscle organ developmentGO:00075171010.013
regulation of response to biotic stimulusGO:000283120.013
regulation of tube sizeGO:003515020.013
cell morphogenesisGO:00009022890.013
positive regulation of immune system processGO:0002684170.013
Human
reactive oxygen species biosynthetic processGO:190340910.013
neural crest cell differentiationGO:0014033720.013
regulation of bindingGO:005109830.013
negative regulation of secretion by cellGO:190353120.013
cellular response to biotic stimulusGO:007121630.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
interspecies interaction between organismsGO:004441940.013
regulation of protein import into nucleusGO:004230620.013
erk1 and erk2 cascadeGO:007037140.013
striated muscle cell differentiationGO:00511461290.013
positive regulation of cellular component biogenesisGO:004408930.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
phosphatidylinositol mediated signalingGO:004801520.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
mesenchymal cell developmentGO:0014031780.012
organelle fusionGO:004828430.012
angiogenesisGO:00015251580.012
Zebrafish
response to hydrogen peroxideGO:004254230.012
tissue regenerationGO:0042246740.012
regulation of gtp catabolic processGO:003312420.012
stem cell differentiationGO:00488631170.012
lateral line developmentGO:0048882660.012
photoreceptor cell developmentGO:0042461400.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
negative regulation of signalingGO:0023057960.012
Zebrafish
regulation of cell killingGO:003134120.012
insulin like growth factor receptor signaling pathwayGO:004800940.012
Zebrafish
peptidyl serine modificationGO:001820920.012
response to copper ionGO:0046688130.012
response to nicotineGO:003509420.012
production of molecular mediator of immune responseGO:000244020.012
meiotic nuclear divisionGO:000712640.012
reactive oxygen species metabolic processGO:007259360.012
striated muscle tissue developmentGO:00147061100.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
mesenchymal cell differentiationGO:0048762870.012
negative regulation of intracellular transportGO:003238730.012
stem cell divisionGO:001714510.012
positive regulation of nucleoside metabolic processGO:004597910.012
response to inorganic substanceGO:0010035380.012
Rat
gene silencing by rnaGO:003104740.012
negative regulation of cytoplasmic transportGO:190365020.012
cell cycle g1 s phase transitionGO:004484310.012
cranial nerve developmentGO:0021545420.012
negative regulation of protein kinase activityGO:000646940.012
locomotionGO:00400113130.012
protein secretionGO:000930610.012
nucleobase containing compound biosynthetic processGO:00346542050.012
muscle cell differentiationGO:00426921390.012
cytokinesisGO:000091030.012
nitric oxide metabolic processGO:004620920.011
synaptic vesicle localizationGO:009747910.011
nuclear migrationGO:000709730.011
cellular amide metabolic processGO:004360340.011
positive regulation of dna metabolic processGO:005105410.011
appendage developmentGO:0048736800.011
response to oxygen containing compoundGO:1901700550.011
Rat
leukocyte mediated cytotoxicityGO:000190910.011
hormone biosynthetic processGO:004244630.011
wnt signaling pathwayGO:0016055800.011
multicellular organismal macromolecule metabolic processGO:004425920.011
regionalizationGO:00030022740.011
microtubule based movementGO:0007018330.011
regulation of oxidative stress induced cell deathGO:190320120.011
circulatory system processGO:0003013870.011
regulation of biosynthetic processGO:00098892500.011
Zebrafish
regulation of autophagyGO:001050630.011
dorsal ventral pattern formationGO:00099531250.011
developmental maturationGO:0021700340.011
negative regulation of tor signalingGO:003200720.011
cell projection organizationGO:00300302840.011
response to endogenous stimulusGO:0009719830.011
Rat
regulation of protein metabolic processGO:0051246560.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
regulation of dna replicationGO:000627530.011
Zebrafish
positive regulation of leukocyte mediated cytotoxicityGO:000191210.011
camera type eye morphogenesisGO:00485931080.011
exocytosisGO:000688710.011
regulation of molecular functionGO:0065009700.011
regulation of protein localization to nucleusGO:190018020.011
response to biotic stimulusGO:0009607970.011
g1 s transition of mitotic cell cycleGO:000008210.011
dna templated transcription elongationGO:000635430.011
regulation of receptor activityGO:001046920.011
actin filament based movementGO:003004810.011
lipid catabolic processGO:001604240.011
negative regulation of multi organism processGO:004390130.010
cellular response to hypoxiaGO:007145610.010
response to transition metal nanoparticleGO:1990267280.010
female sex differentiationGO:004666040.010
positive regulation of epithelial cell differentiationGO:003085820.010
cellular response to stressGO:0033554620.010
epibolyGO:0090504410.010
cell projection morphogenesisGO:00488582440.010
regulation of epithelial cell proliferationGO:005067830.010
axon developmentGO:00615641660.010
positive regulation of secretionGO:005104710.010
cellular component movementGO:00069283350.010
regulation of cell deathGO:00109411030.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
Zebrafish
regulation of behaviorGO:0050795240.010
negative regulation of cysteine type endopeptidase activityGO:200011780.010
regulation of leukocyte mediated immunityGO:000270310.010
regulation of synaptic plasticityGO:004816710.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
regulation of multicellular organismal developmentGO:20000262230.010
protein acylationGO:004354330.010
regulation of cell differentiationGO:00455951420.010
regulation of developmental processGO:00507932470.010
posttranscriptional regulation of gene expressionGO:0010608140.010
embryonic hemopoiesisGO:0035162530.010
neuromast developmentGO:0048884460.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010

igfbp2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.016
sensory system diseaseDOID:005015500.016
eye and adnexa diseaseDOID:149200.015
eye diseaseDOID:561400.015
musculoskeletal system diseaseDOID:1700.013
cardiovascular system diseaseDOID:128700.013
disease of cellular proliferationDOID:1456600.013
hematopoietic system diseaseDOID:7400.012
immune system diseaseDOID:291400.012
retinal diseaseDOID:567900.012
cancerDOID:16200.010