Danio rerio

0 known processes

ints6

integrator complex subunit 6

ints6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle fusionGO:004828430.336
single organism membrane fusionGO:004480120.260
gastrulationGO:00073692080.257
regulation of biological qualityGO:00650082630.183
protein polymerizationGO:005125840.170
apoptotic process involved in developmentGO:190274220.169
mrna metabolic processGO:0016071200.167
membrane fusionGO:006102520.165
digestive tract morphogenesisGO:00485462310.156
regulation of synapse organizationGO:005080730.154
tube morphogenesisGO:00352393490.153
larval developmentGO:000216420.147
mrna processingGO:0006397140.145
stem cell proliferationGO:007208940.121
nucleocytoplasmic transportGO:000691340.120
establishment of localization in cellGO:0051649770.120
agingGO:000756820.117
regulation of cell shapeGO:000836010.114
multi organism processGO:00517041340.110
cell migrationGO:00164772370.104
regulation of establishment of planar polarityGO:009017540.096
nuclear transportGO:005116940.096
digestive tract developmentGO:00485652650.094
single organism organelle organizationGO:19025891990.093
negative regulation of protein transportGO:005122430.090
regulation of meiotic cell cycleGO:005144510.089
mitotic dna damage checkpointGO:004477340.089
regulation of response to stimulusGO:00485832690.086
regulation of ion transmembrane transporter activityGO:003241220.085
protein import into nucleusGO:000660630.084
inorganic ion transmembrane transportGO:0098660570.083
phagocytosisGO:000690930.082
regulation of gene expressionGO:00104682650.082
positive regulation of transportGO:005105020.081
embryo development ending in birth or egg hatchingGO:00097922710.080
single organism transportGO:00447652060.077
morphogenesis of an epitheliumGO:00020093330.077
chemosensory behaviorGO:000763510.076
embryonic organ developmentGO:00485683810.073
gene silencing by rnaGO:003104740.073
cortical actin cytoskeleton organizationGO:003086610.068
multicellular organism growthGO:003526440.068
homeostatic processGO:00425921420.068
regulation of cellular extravasationGO:000269110.067
cell surface receptor signaling pathwayGO:00071663250.067
rna 3 end processingGO:003112320.067
regulation of synapse assemblyGO:005196330.066
primary neural tube formationGO:001402010.066
regulation of protein polymerizationGO:003227120.063
gtp catabolic processGO:000618420.062
regulation of wound healingGO:006104120.062
regulation of protein complex assemblyGO:004325430.061
tissue migrationGO:0090130370.060
exocytosisGO:000688710.059
regulation of cellular metabolic processGO:00313233200.059
cell cycle g1 s phase transitionGO:004484310.057
g2 dna damage checkpointGO:003157230.057
tube closureGO:006060610.057
nitrogen compound metabolic processGO:00068073190.056
regulation of protein localization to nucleusGO:190018020.056
nuclear importGO:005117030.056
receptor recyclingGO:000188140.055
regulation of cell projection assemblyGO:006049140.055
programmed cell deathGO:00125011190.054
negative regulation of cell communicationGO:0010648960.054
cellular localizationGO:0051641970.054
negative regulation of cytoplasmic transportGO:190365020.053
regulation of metal ion transportGO:001095940.053
meiotic nuclear divisionGO:000712640.053
regulation of neutrophil extravasationGO:200038910.052
mitotic dna integrity checkpointGO:004477440.052
heart developmentGO:00075073130.051
cellular macromolecule metabolic processGO:00442603910.051
regulation of phGO:000688530.049
system processGO:00030081850.049
synaptic growth at neuromuscular junctionGO:005112420.049
stem cell maintenanceGO:001982740.049
ion transportGO:00068111140.049
rna metabolic processGO:00160702190.049
melanin metabolic processGO:000658220.048
rna splicingGO:0008380160.048
cell motilityGO:00488702440.047
regulation of primary metabolic processGO:00800903110.047
regulation of transmembrane transporter activityGO:002289820.047
regulation of nucleocytoplasmic transportGO:004682220.046
immune system processGO:00023762410.046
negative regulation of biological processGO:00485193040.046
establishment of protein localization to organelleGO:007259440.046
cation transmembrane transportGO:0098655650.045
cortical cytoskeleton organizationGO:003086510.045
single organism nuclear importGO:190259330.045
leukocyte homeostasisGO:000177620.045
neurological system processGO:0050877620.045
protein targeting to nucleusGO:004474430.044
meiotic cell cycle processGO:190304630.044
neuron projection developmentGO:00311751800.043
establishment of localizationGO:00512342440.043
regulation of exocytosisGO:001715710.043
response to biotic stimulusGO:0009607970.043
transportGO:00068102200.043
mrna cleavage involved in gene silencing by mirnaGO:003527910.043
regulation of response to extracellular stimulusGO:003210410.043
regulation of alternative mrna splicing via spliceosomeGO:000038110.042
stem cell divisionGO:001714510.042
morphogenesis of an epithelial foldGO:006057110.042
response to hormoneGO:0009725480.041
regulation of anatomical structure sizeGO:0090066330.041
protein complex localizationGO:003150310.041
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.041
negative regulation of response to stimulusGO:00485851040.041
regulation of multicellular organism growthGO:004001440.041
regulation of synaptic growth at neuromuscular junctionGO:000858210.040
negative regulation of intracellular protein transportGO:009031730.040
spermatid differentiationGO:004851520.040
regulation of establishment of protein localizationGO:007020140.040
microtubule organizing center organizationGO:003102310.040
response to chemicalGO:00422213200.040
regulation of mrna processingGO:005068430.040
heart loopingGO:0001947940.039
regulation of chromosome segregationGO:005198310.038
peptidyl serine modificationGO:001820920.038
regulation of anatomical structure morphogenesisGO:00226031300.038
cilium movementGO:0003341260.037
locomotor rhythmGO:004547530.037
response to uvGO:000941130.037
immune system developmentGO:00025201910.037
organelle organizationGO:00069962270.037
regulation of protein import into nucleusGO:004230620.037
regulation of reproductive processGO:200024140.037
guanosine containing compound catabolic processGO:190106920.036
taxisGO:00423301090.036
cell migration involved in gastrulationGO:0042074790.036
cellular potassium ion transportGO:0071804100.036
regulation of circadian rhythmGO:004275240.036
regulation of neutrophil migrationGO:190262260.036
embryonic organ morphogenesisGO:00485622740.035
oocyte maturationGO:000155640.035
neuromuscular synaptic transmissionGO:000727420.035
g1 s transition of mitotic cell cycleGO:000008210.035
cell morphogenesis involved in neuron differentiationGO:00486671630.035
gene silencing by mirnaGO:003519530.035
negative regulation of signal transductionGO:0009968940.035
monovalent inorganic cation transportGO:0015672420.035
protein heterooligomerizationGO:005129110.035
peptidyl serine phosphorylationGO:001810510.035
response to stressGO:00069502630.034
regulation of cytoplasmic transportGO:190364940.034
negative regulation of reproductive processGO:200024230.034
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.034
regulation of filopodium assemblyGO:005148920.034
actin filament polymerizationGO:003004120.034
granulocyte migrationGO:0097530110.033
peptidyl threonine phosphorylationGO:001810710.033
single organism localizationGO:19025782250.033
embryonic viscerocranium morphogenesisGO:0048703520.033
negative regulation of catabolic processGO:000989530.033
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.033
ion transmembrane transportGO:0034220910.033
mrna cleavageGO:000637910.032
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.032
negative regulation of intracellular transportGO:003238730.032
neuron migrationGO:0001764220.032
cell deathGO:00082191210.032
mitotic g2 m transition checkpointGO:004481830.032
negative regulation of secretionGO:005104820.032
rna processingGO:0006396250.032
transmembrane transportGO:00550851200.032
protein importGO:001703830.032
regulation of striated muscle contractionGO:000694220.032
cellular component biogenesisGO:00440851780.032
inorganic cation transmembrane transportGO:0098662500.031
cellular aromatic compound metabolic processGO:00067252950.031
guanosine containing compound metabolic processGO:190106840.031
positive regulation of exocytosisGO:004592110.031
spermatid developmentGO:000728620.031
cellular extravasationGO:004512310.031
synaptic vesicle recyclingGO:003646510.031
epithelial tube morphogenesisGO:00605621480.031
regulation of multicellular organismal developmentGO:20000262230.030
mitotic g2 dna damage checkpointGO:000709530.030
gtp metabolic processGO:004603940.030
negative regulation of nuclear divisionGO:005178430.030
cardiac atrium developmentGO:000323040.030
myeloid leukocyte migrationGO:0097529120.030
growthGO:00400071740.030
ubiquitin dependent protein catabolic processGO:000651130.030
regulation of blood vessel sizeGO:005088020.030
hormone secretionGO:004687920.030
centrosome organizationGO:005129710.029
positive regulation of cell adhesionGO:004578510.029
response to abiotic stimulusGO:00096281220.029
regulation of protein transportGO:005122330.029
regulation of synaptic plasticityGO:004816710.029
developmental programmed cell deathGO:001062340.029
regulation of cytokine productionGO:000181730.029
neutrophil mediated immunityGO:000244610.029
hormone transportGO:000991420.029
regulation of response to nutrient levelsGO:003210710.029
localization of cellGO:00516742440.029
cellular protein metabolic processGO:00442671290.028
organic cyclic compound metabolic processGO:19013603010.028
meiosis iGO:000712710.028
regulation of localizationGO:00328791040.028
synaptic vesicle localizationGO:009747910.028
negative regulation of defense responseGO:003134820.028
nucleic acid metabolic processGO:00903042440.028
mitochondrial transportGO:000683920.027
regulation of cell sizeGO:0008361290.027
negative regulation of smoothened signaling pathwayGO:004587960.027
cellular ketone metabolic processGO:0042180110.027
maintenance of locationGO:005123540.027
regulation of developmental processGO:00507932470.027
digestive tract mesoderm developmentGO:000750210.027
spindle assembly involved in meiosisGO:009030610.027
positive regulation of secretion by cellGO:190353210.027
negative regulation of cellular catabolic processGO:003133030.027
regulation of rna metabolic processGO:00512522240.027
cellular lipid metabolic processGO:0044255360.026
regulation of tube sizeGO:003515020.026
negative regulation of protein import into nucleusGO:004230820.026
regulation of bindingGO:005109830.026
regulation of multicellular organismal processGO:00512392770.026
regulation of cellular biosynthetic processGO:00313262450.026
response to drugGO:004249330.026
nucleobase containing compound biosynthetic processGO:00346542050.026
actin polymerization or depolymerizationGO:000815420.026
neurotransmitter transportGO:000683620.026
lamellipodium assemblyGO:003003210.026
negative regulation of protein serine threonine kinase activityGO:007190120.026
positive regulation of secretionGO:005104710.026
wound healingGO:0042060900.026
erythrocyte homeostasisGO:0034101550.025
regulation of apoptotic processGO:0042981980.025
nucleobase containing compound metabolic processGO:00061392740.025
heterocycle metabolic processGO:00464832900.025
regulation of system processGO:0044057400.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
negative regulation of protein phosphorylationGO:000193340.025
regulation of stem cell differentiationGO:200073640.025
regulation of inflammatory responseGO:005072720.025
synaptic vesicle transportGO:004848910.025
cellular response to organic cyclic compoundGO:0071407380.025
negative regulation of secretion by cellGO:190353120.025
regulation of nucleic acid templated transcriptionGO:19035062130.024
sensory perception of smellGO:000760820.024
chordate embryonic developmentGO:00430092710.024
somatic muscle developmentGO:000752540.024
fertilizationGO:000956630.024
regulation of transporter activityGO:003240920.024
cellular response to organic substanceGO:00713101050.024
sensory perception of chemical stimulusGO:000760630.024
ribonucleoside monophosphate catabolic processGO:000915840.024
wnt signaling pathway planar cell polarity pathwayGO:006007140.024
neutrophil migrationGO:1990266100.024
macromolecular complex disassemblyGO:003298410.024
ear developmentGO:00435831270.024
peptide transportGO:001583310.024
nucleic acid templated transcriptionGO:00976591810.024
negative regulation of cellular processGO:00485232830.024
rna localizationGO:000640340.023
regulation of intracellular phGO:005145310.023
alcohol biosynthetic processGO:004616520.023
regulation of cellular amino acid metabolic processGO:000652100.023
negative regulation of nucleocytoplasmic transportGO:004682320.023
morphogenesis of a branching structureGO:0001763210.023
cellular biosynthetic processGO:00442492860.023
cardiac atrium morphogenesisGO:000320920.023
response to hexoseGO:000974630.023
regulation of nervous system developmentGO:0051960900.023
ameboidal type cell migrationGO:00016671430.023
amine metabolic processGO:000930820.023
organic substance biosynthetic processGO:19015762890.023
nuclear exportGO:005116810.023
neuroblast proliferationGO:000740520.023
modification dependent protein catabolic processGO:001994130.023
somatic stem cell maintenanceGO:003501910.022
oocyte anterior posterior axis specificationGO:000731440.022
cell projection morphogenesisGO:00488582440.022
protein localization to nucleusGO:003450430.022
metal ion transportGO:0030001580.022
gene expressionGO:00104672520.022
regulation of cell motilityGO:2000145460.022
negative regulation of protein localization to nucleusGO:190018120.022
response to radiationGO:0009314510.022
cell cycle arrestGO:000705010.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
proteasomal protein catabolic processGO:001049820.022
regulation of metabolic processGO:00192223590.022
positive regulation of cellular component biogenesisGO:004408930.022
centrosome cycleGO:000709810.022
epithelium migrationGO:0090132250.022
small molecule metabolic processGO:0044281770.021
protein dephosphorylationGO:000647030.021
atp catabolic processGO:000620040.021
cell proliferationGO:0008283800.021
negative regulation of mitotic cell cycleGO:0045930110.021
embryonic digestive tract morphogenesisGO:004855730.021
regulation of cell migrationGO:0030334400.021
regulation of reactive oxygen species metabolic processGO:200037720.021
response to glucocorticoidGO:005138410.021
actin filament based processGO:0030029640.021
keratinocyte differentiationGO:003021600.021
rhombomere 5 developmentGO:002157140.021
protein localization to plasma membraneGO:007265910.021
embryonic digestive tract developmentGO:004856640.021
cation transportGO:0006812810.021
regulation of cell communicationGO:00106462320.020
positive regulation of catabolic processGO:000989640.020
regulation of myotube differentiationGO:001083020.020
negative regulation of translationGO:001714810.020
regulation of cellular amine metabolic processGO:003323800.020
myeloid cell homeostasisGO:0002262560.020
cell proliferation involved in heart morphogenesisGO:006132320.020
convergent extensionGO:00600261180.020
synaptic vesicle endocytosisGO:004848810.020
response to organic substanceGO:00100331530.020
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.020
desmosome organizationGO:000293430.020
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.020
purine nucleoside monophosphate catabolic processGO:000912840.020
rho protein signal transductionGO:000726650.020
gene silencingGO:001645840.020
mrna 3 end processingGO:003112420.020
positive regulation of cell substrate adhesionGO:001081110.020
regulation of mitochondrion organizationGO:001082110.020
positive regulation of muscle cell differentiationGO:005114910.020
regulation of protein catabolic processGO:004217610.020
regulation of microtubule cytoskeleton organizationGO:007050730.019
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.019
polyol metabolic processGO:001975110.019
oxoacid metabolic processGO:0043436310.019
phagocytosis engulfmentGO:000691110.019
cellular nitrogen compound metabolic processGO:00346412900.019
protein complex disassemblyGO:004324110.019
vasculature developmentGO:00019442780.019
olfactory lobe developmentGO:002198840.019
signal transductionGO:00071654550.019
regulation of intracellular protein transportGO:003315730.019
protein polyubiquitinationGO:000020940.019
positive regulation of synapse assemblyGO:005196510.019
periodic partitioningGO:000736510.019
heterocycle biosynthetic processGO:00181302150.019
regulation of cell proliferation involved in heart morphogenesisGO:200013620.019
axon developmentGO:00615641660.019
regulation of sodium ion transportGO:000202820.019
regulation of cellular component sizeGO:0032535300.019
negative regulation of signalingGO:0023057960.019
odontogenesis of dentin containing toothGO:004247510.018
pigment granule transportGO:0051904190.018
determination of bilateral symmetryGO:00098552040.018
response to hydrogen peroxideGO:004254230.018
cell substrate adhesionGO:003158940.018
cartilage developmentGO:0051216960.018
embryonic heart tube morphogenesisGO:00031431080.018
motor neuron axon guidanceGO:0008045230.018
one carbon compound transportGO:0019755140.018
female gonad developmentGO:000858540.018
transcription from rna polymerase ii promoterGO:0006366800.018
cell part morphogenesisGO:00329902460.018
neuron developmentGO:00486662620.018
apoptotic processGO:00069151160.018
negative regulation of gliogenesisGO:001401410.018
pyrimidine containing compound metabolic processGO:007252730.018
sensory perceptionGO:0007600390.018
regulation of neurogenesisGO:0050767870.018
establishment of protein localization to plasma membraneGO:009000210.018
positive regulation of proteolysisGO:0045862100.018
response to woundingGO:00096111160.018
single organism metabolic processGO:00447102170.018
regulation of dna templated transcription elongationGO:003278430.018
regulation of molecular functionGO:0065009700.018
multi organism reproductive processGO:0044703360.018
glial cell proliferationGO:001400940.018
regulation of neuronal synaptic plasticityGO:004816810.018
non canonical wnt signaling pathwayGO:0035567130.017
neutrophil extravasationGO:007267210.017
regulation of cellular component movementGO:0051270550.017
blood vessel developmentGO:00015682460.017
negative regulation of chemotaxisGO:005092240.017
negative regulation of protein kinase activityGO:000646940.017
chemotaxisGO:00069351040.017
actin cytoskeleton organizationGO:0030036630.017
lamellipodium organizationGO:009758110.017
nucleoside monophosphate catabolic processGO:000912540.017
response to nutrientGO:000758430.017
response to carbohydrateGO:000974330.017
response to external stimulusGO:00096052640.017
cell projection organizationGO:00300302840.017
regulation of cell activationGO:005086510.017
digestive system developmentGO:00551232890.017
posttranscriptional gene silencingGO:001644130.017
positive regulation of cell cycleGO:004578730.017
regulation of cell deathGO:00109411030.017
cell morphogenesis involved in differentiationGO:00009041950.017
formation of primary germ layerGO:0001704620.017
renal system developmentGO:0072001940.017
germ line stem cell divisionGO:004207810.017
cell agingGO:000756920.017
endosomal transportGO:001619720.017
cell cycle g2 m phase transitionGO:004483940.017
mesenchymal cell differentiationGO:0048762870.017
cellular response to hormone stimulusGO:0032870390.017
positive regulation of neutrophil extravasationGO:200039110.017
dna templated transcription elongationGO:000635430.017
sprouting angiogenesisGO:0002040530.017
regulation of hormone secretionGO:004688320.017
regulation of neuron differentiationGO:0045664560.016
secondary metabolic processGO:001974830.016
regulation of cellular phGO:003064110.016
intracellular signal transductionGO:0035556850.016
blood circulationGO:0008015870.016
regulation of cytoskeleton organizationGO:0051493110.016
carbohydrate homeostasisGO:003350010.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
protein metabolic processGO:00195381830.016
neuron projection morphogenesisGO:00488121610.016
spindle assemblyGO:005122520.016
embryonic limb morphogenesisGO:003032620.016
negative regulation of map kinase activityGO:004340720.016
regulation of macromolecule biosynthetic processGO:00105562250.016
kidney developmentGO:0001822920.016
response to glucoseGO:000974930.016
nose developmentGO:004358430.016
macromolecule biosynthetic processGO:00090592270.016
modification dependent macromolecule catabolic processGO:004363230.016
pronephros developmentGO:0048793690.016
meiotic chromosome segregationGO:004513230.016
positive regulation of neutrophil migrationGO:190262400.016
leukocyte mediated immunityGO:000244360.016
axonal defasciculationGO:000741420.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
cellular component disassemblyGO:002241110.016
negative regulation of chromosome organizationGO:200125110.015
cytoskeleton dependent cytokinesisGO:006164030.015
cell junction maintenanceGO:003433120.015
cellular component movementGO:00069283350.015
cellular response to extracellular stimulusGO:003166820.015
protein homooligomerizationGO:005126030.015
gamete generationGO:0007276330.015
regulation of programmed cell deathGO:00430671010.015
alternative mrna splicing via spliceosomeGO:000038010.015
cellular macromolecule biosynthetic processGO:00346452240.015
startle responseGO:000196440.015
regulation of jak stat cascadeGO:004642530.015
smooth muscle contractionGO:000693920.015
regulation of cell developmentGO:00602841000.015
endocardium morphogenesisGO:000316040.015
single organismal cell cell adhesionGO:0016337290.015
autophagyGO:000691440.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
multicellular organismal reproductive processGO:0048609350.015
cellular amino acid metabolic processGO:000652070.015
limb bud formationGO:006017420.015
developmental growthGO:00485891660.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
response to topologically incorrect proteinGO:003596620.015
regulation of cellular ketone metabolic processGO:001056570.015
angiogenesisGO:00015251580.015
regulation of transportGO:0051049450.015
positive regulation of jnk cascadeGO:004633030.015
endoderm developmentGO:0007492490.015
macromolecular complex assemblyGO:0065003350.015
pigment granule localizationGO:0051875250.015
organic substance transportGO:0071702580.015
ventricular cardiac muscle tissue developmentGO:000322930.015
hemopoiesisGO:00300971830.015
sexual reproductionGO:0019953360.015
anterior posterior pattern specificationGO:00099521520.015
cellular component morphogenesisGO:00329893360.015
posttranscriptional gene silencing by rnaGO:003519430.015
cellular monovalent inorganic cation homeostasisGO:003000420.015
lateral inhibitionGO:004633110.014
regulation of signal transductionGO:00099662250.014
response to estrogenGO:0043627270.014
sensory organ developmentGO:00074233930.014
developmental growth involved in morphogenesisGO:0060560860.014
peptidyl threonine modificationGO:001821010.014
rna polyadenylationGO:004363120.014
spliceosomal snrnp assemblyGO:000038720.014
chromosome organization involved in meiosisGO:007019210.014
regulation of neural precursor cell proliferationGO:200017730.014
neuron remodelingGO:001632210.014

ints6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.109
musculoskeletal system diseaseDOID:1700.049
cardiovascular system diseaseDOID:128700.029
heart diseaseDOID:11400.029
muscular diseaseDOID:008000000.029
intrinsic cardiomyopathyDOID:006003600.029
myopathyDOID:42300.029
cardiomyopathyDOID:005070000.029
muscle tissue diseaseDOID:6600.029
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.019
nervous system diseaseDOID:86300.018
sensory system diseaseDOID:005015500.015