Danio rerio

0 known processes

ints8

integrator complex subunit 8

(Aliases: MGC111823,zgc:111823)

ints8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.428
embryo development ending in birth or egg hatchingGO:00097922710.194
meiotic nuclear divisionGO:000712640.147
locomotionGO:00400113130.088
cellular macromolecule metabolic processGO:00442603910.088
Human
positive regulation of chromatin modificationGO:190331010.082
meiotic cell cycle processGO:190304630.074
regulation of macromolecule metabolic processGO:00602553170.072
ribonucleoside monophosphate catabolic processGO:000915840.071
purine nucleoside monophosphate catabolic processGO:000912840.068
regulation of nitrogen compound metabolic processGO:00511712510.068
nucleoside monophosphate catabolic processGO:000912540.067
atp catabolic processGO:000620040.066
nitrogen compound metabolic processGO:00068073190.061
Human
rna metabolic processGO:00160702190.060
Human
positive regulation of cell cycleGO:004578730.056
cellular nitrogen compound metabolic processGO:00346412900.054
Human
regulation of metabolic processGO:00192223590.051
cellular component morphogenesisGO:00329893360.051
purine ribonucleoside monophosphate catabolic processGO:000916940.050
regulation of multicellular organism growthGO:004001440.049
regulation of nucleobase containing compound metabolic processGO:00192192500.047
negative regulation of nuclear divisionGO:005178430.045
regulation of gene expressionGO:00104682650.044
gene expressionGO:00104672520.044
Human
nucleobase containing compound biosynthetic processGO:00346542050.043
cell cycleGO:0007049930.043
organelle fissionGO:0048285230.042
organelle organizationGO:00069962270.042
cell morphogenesisGO:00009022890.041
cytoskeleton dependent cytokinesisGO:006164030.041
regulation of protein catabolic processGO:004217610.040
cell migrationGO:00164772370.040
regulation of cellular metabolic processGO:00313233200.040
meiotic chromosome segregationGO:004513230.038
double strand break repair via homologous recombinationGO:000072410.038
multicellular organism growthGO:003526440.038
lipid storageGO:001991510.036
single organism organelle organizationGO:19025891990.036
blood vessel developmentGO:00015682460.036
nucleic acid metabolic processGO:00903042440.035
Human
macromolecule biosynthetic processGO:00090592270.035
protein metabolic processGO:00195381830.034
agingGO:000756820.034
maintenance of locationGO:005123540.034
blood vessel morphogenesisGO:00485142160.033
organic substance biosynthetic processGO:19015762890.033
cellular response to extracellular stimulusGO:003166820.033
negative regulation of protein transportGO:005122430.033
sister chromatid cohesionGO:000706220.032
protein acetylationGO:000647320.032
vasculature developmentGO:00019442780.032
heart developmentGO:00075073130.032
stem cell maintenanceGO:001982740.032
regulation of primary metabolic processGO:00800903110.031
cellular component movementGO:00069283350.031
microtubule organizing center organizationGO:003102310.031
cellular carbohydrate metabolic processGO:004426240.031
fertilizationGO:000956630.031
negative regulation of cellular processGO:00485232830.030
cell cycle g1 s phase transitionGO:004484310.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
single fertilizationGO:000733830.030
macromolecule modificationGO:00434121110.030
neuron differentiationGO:00301823530.030
transportGO:00068102200.029
regulation of meiotic cell cycleGO:005144510.029
tube morphogenesisGO:00352393490.029
nucleic acid templated transcriptionGO:00976591810.029
neuron developmentGO:00486662620.028
cellular response to external stimulusGO:007149620.028
multi organism processGO:00517041340.028
cell morphogenesis involved in differentiationGO:00009041950.028
organic cyclic compound biosynthetic processGO:19013622230.027
cell cycle processGO:0022402530.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
single organism metabolic processGO:00447102170.027
nucleobase containing compound metabolic processGO:00061392740.026
Human
protein modification processGO:00362111000.026
response to chemicalGO:00422213200.026
generation of neuronsGO:00486993850.026
double strand break repairGO:000630230.026
organic cyclic compound metabolic processGO:19013603010.025
Human
neuron projection developmentGO:00311751800.025
oxoacid metabolic processGO:0043436310.025
negative regulation of biological processGO:00485193040.025
centrosome organizationGO:005129710.025
negative regulation of synapse assemblyGO:005196420.025
heterocycle metabolic processGO:00464832900.024
Human
phagocytosisGO:000690930.024
digestive system developmentGO:00551232890.024
cell projection organizationGO:00300302840.024
regulation of rna metabolic processGO:00512522240.024
cell part morphogenesisGO:00329902460.024
stem cell proliferationGO:007208940.024
mitotic cell cycleGO:0000278640.024
rna biosynthetic processGO:00327741810.024
positive regulation of cellular amino acid metabolic processGO:004576400.024
meiosis iGO:000712710.024
digestive tract morphogenesisGO:00485462310.024
apoptotic processGO:00069151160.023
cytokinesisGO:000091030.023
digestive tract developmentGO:00485652650.023
positive regulation of cellular amine metabolic processGO:003324000.023
protein dephosphorylationGO:000647030.023
regulation of chromosome segregationGO:005198310.023
cellular amine metabolic processGO:004410620.023
autophagyGO:000691440.023
protein acylationGO:004354330.023
ameboidal type cell migrationGO:00016671430.023
positive regulation of dna metabolic processGO:005105410.023
heterocycle biosynthetic processGO:00181302150.022
positive regulation of cytoskeleton organizationGO:005149530.022
cellular component assemblyGO:00226071700.022
regulation of protein complex assemblyGO:004325430.022
regulation of cellular ketone metabolic processGO:001056570.022
regulation of stem cell proliferationGO:007209120.022
morphogenesis of an epitheliumGO:00020093330.022
cell deathGO:00082191210.021
regulation of cellular amino acid metabolic processGO:000652100.021
recombinational repairGO:000072510.021
regulation of synapse organizationGO:005080730.021
internal protein amino acid acetylationGO:000647520.021
extrinsic apoptotic signaling pathwayGO:009719130.021
regulation of cellular amine metabolic processGO:003323800.020
cellular component biogenesisGO:00440851780.020
immune system developmentGO:00025201910.020
embryonic digestive tract developmentGO:004856640.020
b cell activationGO:004211320.020
positive regulation of chromosome organizationGO:200125210.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
localization of cellGO:00516742440.020
regulation of establishment of protein localizationGO:007020140.020
regulation of circadian rhythmGO:004275240.020
g1 s transition of mitotic cell cycleGO:000008210.020
cellular biosynthetic processGO:00442492860.020
angiogenesisGO:00015251580.020
synaptic growth at neuromuscular junctionGO:005112420.020
regulation of nucleic acid templated transcriptionGO:19035062130.019
small molecule metabolic processGO:0044281770.019
regulation of dna recombinationGO:000001820.019
transcription dna templatedGO:00063511810.019
regulation of protein transportGO:005122330.019
carboxylic acid metabolic processGO:0019752220.019
positive regulation of catabolic processGO:000989640.019
positive regulation of cell activationGO:005086710.019
regulation of macromolecule biosynthetic processGO:00105562250.019
biosynthetic processGO:00090582940.019
production of molecular mediator of immune responseGO:000244020.019
mitotic dna integrity checkpointGO:004477440.018
regulation of rna biosynthetic processGO:20011412130.018
regulation of multicellular organismal processGO:00512392770.018
programmed cell deathGO:00125011190.018
brain developmentGO:00074202930.018
mononuclear cell proliferationGO:003294310.018
nuclear divisionGO:0000280230.018
embryonic organ developmentGO:00485683810.018
regulation of cellular biosynthetic processGO:00313262450.018
regulation of cell shapeGO:000836010.018
lymphocyte proliferationGO:004665110.018
regulation of cellular component organizationGO:0051128860.018
mitotic nuclear divisionGO:0007067180.018
nuclear migrationGO:000709730.018
amine metabolic processGO:000930820.018
regulation of cell activationGO:005086510.017
cell cycle arrestGO:000705010.017
protein polymerizationGO:005125840.017
internal peptidyl lysine acetylationGO:001839320.017
positive regulation of cellular component biogenesisGO:004408930.017
centrosome duplicationGO:005129810.017
leukocyte proliferationGO:007066110.017
stem cell divisionGO:001714510.017
response to drugGO:004249330.017
cell projection morphogenesisGO:00488582440.016
epithelial tube morphogenesisGO:00605621480.016
regulation of biosynthetic processGO:00098892500.016
organic acid metabolic processGO:0006082310.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
developmental growthGO:00485891660.016
sexual reproductionGO:0019953360.016
negative regulation of catabolic processGO:000989530.016
peptidyl lysine acetylationGO:001839420.016
protein importGO:001703830.016
regulation of biological qualityGO:00650082630.016
regulation of developmental processGO:00507932470.016
cellular amino acid metabolic processGO:000652070.016
hatchingGO:003518840.016
regulation of multicellular organismal developmentGO:20000262230.016
regulation of cytoplasmic transportGO:190364940.016
nucleocytoplasmic transportGO:000691340.016
positive regulation of biological processGO:00485182530.015
central nervous system developmentGO:00074173870.015
growthGO:00400071740.015
telomere maintenanceGO:000072310.015
histone h3 k4 methylationGO:005156820.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
negative regulation of protein phosphorylationGO:000193340.015
sensory organ morphogenesisGO:00905962000.015
positive regulation of histone modificationGO:003105810.015
chordate embryonic developmentGO:00430092710.015
head developmentGO:00603223030.015
regulation of cytokine productionGO:000181730.015
response to stressGO:00069502630.015
dna templated transcription initiationGO:000635210.015
aromatic compound biosynthetic processGO:00194382170.015
carbohydrate biosynthetic processGO:001605110.015
developmental process involved in reproductionGO:0003006270.015
negative regulation of dna metabolic processGO:005105340.015
regulation of synapse assemblyGO:005196330.015
rna localizationGO:000640340.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
spindle assemblyGO:005122520.015
cellular ketone metabolic processGO:0042180110.015
protein complex localizationGO:003150310.015
negative regulation of intracellular transportGO:003238730.014
reproductionGO:0000003400.014
cellular process involved in reproduction in multicellular organismGO:0022412280.014
negative regulation of macromolecule metabolic processGO:0010605760.014
cell motilityGO:00488702440.014
regionalizationGO:00030022740.014
positive regulation of transportGO:005105020.014
establishment of protein localization to organelleGO:007259440.014
regulation of dna replicationGO:000627530.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of bindingGO:005109830.014
cell substrate adhesionGO:003158940.014
establishment of localizationGO:00512342440.014
reciprocal dna recombinationGO:003582510.014
chromosome organization involved in meiosisGO:007019210.014
regulation of metal ion transportGO:001095940.014
gtp catabolic processGO:000618420.014
rna transportGO:005065820.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
sensory organ developmentGO:00074233930.013
response to monosaccharideGO:003428430.013
convergent extension involved in gastrulationGO:0060027710.013
immune system processGO:00023762410.013
negative regulation of cytoplasmic transportGO:190365020.013
multicellular organism reproductionGO:0032504350.013
negative regulation of small gtpase mediated signal transductionGO:005105810.013
cytoskeleton organizationGO:0007010960.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
regulation of histone methylationGO:003106030.013
gtp metabolic processGO:004603940.013
regulation of production of molecular mediator of immune responseGO:000270010.013
g2 m transition of mitotic cell cycleGO:000008640.013
single organism localizationGO:19025782250.013
mitotic sister chromatid segregationGO:000007060.013
neuron projection morphogenesisGO:00488121610.013
epithelial cell morphogenesisGO:000338220.013
cellular response to nutrient levelsGO:003166920.013
nuclear transportGO:005116940.013
positive regulation of protein complex assemblyGO:003133420.013
mitotic cell cycle processGO:1903047480.013
cellular protein metabolic processGO:00442671290.013
specification of symmetryGO:00097992040.012
primary neural tube formationGO:001402010.012
g2 dna damage checkpointGO:003157230.012
positive regulation of immune effector processGO:000269930.012
cellular macromolecule biosynthetic processGO:00346452240.012
cellular component disassemblyGO:002241110.012
response to hexoseGO:000974630.012
endocytosisGO:0006897160.012
macromolecular complex disassemblyGO:003298410.012
reciprocal meiotic recombinationGO:000713110.012
cell divisionGO:0051301200.012
mitochondrion organizationGO:000700540.012
nuclear exportGO:005116810.012
cognitionGO:005089010.012
regulation of anatomical structure morphogenesisGO:00226031300.012
protein heterooligomerizationGO:005129110.012
chromosome organizationGO:0051276310.012
cellular protein modification processGO:00064641000.012
centrosome cycleGO:000709810.012
transcription from rna polymerase ii promoterGO:0006366800.012
mitotic cytokinesisGO:000028130.012
proteasomal protein catabolic processGO:001049820.012
organic acid catabolic processGO:001605430.012
regulation of cell cycleGO:0051726520.012
axon developmentGO:00615641660.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
regulation of protein ubiquitinationGO:003139630.012
taxisGO:00423301090.012
response to uvGO:000941130.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
secondary metabolic processGO:001974830.012
negative regulation of nucleocytoplasmic transportGO:004682320.011
response to carbohydrateGO:000974330.011
ribosome assemblyGO:004225510.011
dna metabolic processGO:0006259270.011
guanosine containing compound metabolic processGO:190106840.011
regulation of nucleoside metabolic processGO:000911820.011
regulation of nucleotide catabolic processGO:003081120.011
regulation of protein localization to nucleusGO:190018020.011
muscle structure developmentGO:00610611960.011
regulation of cell differentiationGO:00455951420.011
lipid catabolic processGO:001604240.011
multi organism reproductive processGO:0044703360.011
cell cycle g2 m phase transitionGO:004483940.011
determination of left right symmetryGO:00073681790.011
regulation of neural precursor cell proliferationGO:200017730.011
axonogenesisGO:00074091520.011
positive regulation of secretionGO:005104710.011
regulation of carbohydrate biosynthetic processGO:004325510.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of blood pressureGO:000821710.011
regulation of apoptotic processGO:0042981980.011
b cell mediated immunityGO:001972430.011
neurological system processGO:0050877620.011
regulation of intracellular protein transportGO:003315730.011
response to glucoseGO:000974930.011
embryonic organ morphogenesisGO:00485622740.011
embryonic digestive tract morphogenesisGO:004855730.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
regulation of autophagyGO:001050630.011
eye developmentGO:00016542770.011
regulation of mitotic cell cycleGO:0007346250.011
cellular response to dna damage stimulusGO:0006974240.011
tube closureGO:006060610.011
mitotic recombinationGO:000631220.011
negative regulation of chromosome organizationGO:200125110.010
chemotaxisGO:00069351040.010
immunoglobulin mediated immune responseGO:001606430.010
gastrulationGO:00073692080.010
organism emergence from protective structureGO:007168440.010
regulation of cell cycle processGO:0010564200.010
carbohydrate homeostasisGO:003350010.010
cellular response to starvationGO:000926710.010
positive regulation of cellular catabolic processGO:003133130.010
protein localization to nucleusGO:003450430.010
regulation of epithelial cell proliferationGO:005067830.010
system processGO:00030081850.010
lipid homeostasisGO:005508830.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.010
hemopoiesisGO:00300971830.010
cellular response to oxygen levelsGO:007145310.010
response to corticosteroidGO:003196010.010
neuroblast proliferationGO:000740520.010
regulation of sodium ion transportGO:000202820.010

ints8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
nervous system diseaseDOID:86300.032
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.014
myopathyDOID:42300.010
muscular diseaseDOID:008000000.010
intrinsic cardiomyopathyDOID:006003600.010
cardiovascular system diseaseDOID:128700.010
heart diseaseDOID:11400.010
muscle tissue diseaseDOID:6600.010
cardiomyopathyDOID:005070000.010
musculoskeletal system diseaseDOID:1700.010