Danio rerio

13 known processes

pklr

pyruvate kinase, liver and RBC

(Aliases: wu:fd15e01,wu:fi37e08)

pklr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
morphogenesis of an epitheliumGO:00020093330.282
agingGO:000756820.181
cellular macromolecule metabolic processGO:00442603910.141
regulation of wound healingGO:006104120.115
cellular protein catabolic processGO:004425740.103
response to biotic stimulusGO:0009607970.079
gene expressionGO:00104672520.073
negative regulation of biological processGO:00485193040.073
localization of cellGO:00516742440.071
organic acid metabolic processGO:0006082310.071
response to external stimulusGO:00096052640.067
cell motilityGO:00488702440.067
negative regulation of protein processingGO:0010955100.066
organic heteropentacyclic compound metabolic processGO:190137610.066
muscle structure developmentGO:00610611960.065
regulation of biological qualityGO:00650082630.064
regulation of transcription dna templatedGO:00063552130.063
negative regulation of cellular processGO:00485232830.059
cellular response to chemical stimulusGO:00708871570.057
larval developmentGO:000216420.056
regulation of blood coagulationGO:003019310.056
renal tubule morphogenesisGO:006133310.056
developmental growthGO:00485891660.055
regulation of gene expressionGO:00104682650.053
negative regulation of endopeptidase activityGO:0010951100.050
killing of cells in other organism involved in symbiotic interactionGO:005188310.050
positive regulation of response to stimulusGO:0048584800.050
maintenance of locationGO:005123540.049
cellular ketone metabolic processGO:0042180110.048
growthGO:00400071740.047
mycotoxin metabolic processGO:004338510.047
regulation of signal transductionGO:00099662250.046
regulation of cellular metabolic processGO:00313233200.044
neuron differentiationGO:00301823530.044
modification dependent macromolecule catabolic processGO:004363230.043
response to organic substanceGO:00100331530.041
positive regulation of wound healingGO:009030310.040
response to organic cyclic compoundGO:0014070510.039
regulation of response to stimulusGO:00485832690.038
single organism metabolic processGO:00447102170.038
tube morphogenesisGO:00352393490.038
system processGO:00030081850.037
digestive tract developmentGO:00485652650.037
response to lipidGO:0033993600.037
head developmentGO:00603223030.036
regulation of primary metabolic processGO:00800903110.036
heart loopingGO:0001947940.036
regulation of cell substrate adhesionGO:001081010.035
lipid storageGO:001991510.034
regulation of protein catabolic processGO:004217610.034
cellular response to external stimulusGO:007149620.033
response to endogenous stimulusGO:0009719830.033
cellular component morphogenesisGO:00329893360.033
regulation of hemostasisGO:190004610.033
digestive system developmentGO:00551232890.033
cellular amino acid metabolic processGO:000652070.032
protein metabolic processGO:00195381830.032
cellular response to hormone stimulusGO:0032870390.032
central nervous system developmentGO:00074173870.031
cellular response to estrogen stimulusGO:0071391240.031
regulation of protein maturationGO:1903317100.031
cellular component movementGO:00069283350.031
ether metabolic processGO:001890410.030
organic acid catabolic processGO:001605430.030
ameboidal type cell migrationGO:00016671430.030
regulation of metal ion transportGO:001095940.030
proteolysisGO:0006508380.030
regulation of tube sizeGO:003515020.030
regulation of extrinsic apoptotic signaling pathwayGO:200123630.029
regulation of blood vessel sizeGO:005088020.029
circulatory system processGO:0003013870.029
transcription dna templatedGO:00063511810.028
response to chemicalGO:00422213200.028
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.028
positive regulation of transportGO:005105020.028
lipid oxidationGO:003444010.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
heterocycle metabolic processGO:00464832900.027
negative regulation of cellular metabolic processGO:0031324770.027
cellular response to starvationGO:000926710.027
cellular response to steroid hormone stimulusGO:0071383310.027
meiotic nuclear divisionGO:000712640.026
lipid catabolic processGO:001604240.026
response to woundingGO:00096111160.026
positive regulation of signalingGO:0023056560.026
regulation of multicellular organismal processGO:00512392770.026
proteolysis involved in cellular protein catabolic processGO:005160330.025
proteasomal protein catabolic processGO:001049820.025
cell substrate adhesionGO:003158940.025
regulation of macromolecule metabolic processGO:00602553170.025
cellular response to endogenous stimulusGO:0071495680.025
epithelial tube morphogenesisGO:00605621480.024
multicellular organism growthGO:003526440.024
mesenchymal cell differentiationGO:0048762870.024
locomotionGO:00400113130.024
positive regulation of cellular amine metabolic processGO:003324000.024
cellular response to nutrient levelsGO:003166920.024
pyruvate metabolic processGO:000609010.024
ubiquitin dependent protein catabolic processGO:000651130.023
positive regulation of cell cycleGO:004578730.023
regulation of cytokine productionGO:000181730.023
cellular response to organic substanceGO:00713101050.023
cell adhesionGO:0007155400.023
blood coagulation fibrin clot formationGO:007237830.023
regulation of cellular amino acid metabolic processGO:000652100.023
single organism organelle organizationGO:19025891990.022
hormone secretionGO:004687920.022
regulation of protein transportGO:005122330.022
tissue regenerationGO:0042246740.022
brain developmentGO:00074202930.022
regulation of establishment of protein localizationGO:007020140.022
regulation of organ growthGO:004662030.022
cell migrationGO:00164772370.022
regulation of tyrosine phosphorylation of stat proteinGO:004250910.021
nucleic acid templated transcriptionGO:00976591810.021
aflatoxin b1 metabolic processGO:004339010.021
extrinsic apoptotic signaling pathwayGO:009719130.021
phagocytosisGO:000690930.021
cellular response to extracellular stimulusGO:003166820.021
small molecule catabolic processGO:004428230.020
negative regulation of multicellular organismal processGO:0051241690.020
oxoacid metabolic processGO:0043436310.020
glucose homeostasisGO:004259310.020
regulation of multicellular organism growthGO:004001440.020
immune system processGO:00023762410.020
response to steroid hormoneGO:0048545350.019
regulation of signalingGO:00230512350.019
positive regulation of cell communicationGO:0010647560.019
signal transductionGO:00071654550.019
blood circulationGO:0008015870.019
astrocyte differentiationGO:004870810.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.018
regulation of cellular amine metabolic processGO:003323800.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
rna biosynthetic processGO:00327741810.018
positive regulation of cellular processGO:00485222010.018
gastrulationGO:00073692080.018
epithelial cell differentiationGO:00308551160.018
interspecies interaction between organismsGO:004441940.018
cell morphogenesisGO:00009022890.018
response to estrogenGO:0043627270.018
amine metabolic processGO:000930820.018
mesenchyme developmentGO:00604851270.018
regulation of coagulationGO:005081820.018
glucocorticoid metabolic processGO:000821120.017
cell matrix adhesionGO:000716040.017
blood coagulationGO:0007596120.017
response to stressGO:00069502630.017
translational initiationGO:000641330.017
aflatoxin metabolic processGO:004622210.017
regulation of protein processingGO:0070613100.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
regulation of fatty acid metabolic processGO:001921710.017
protein secretionGO:000930610.017
epibolyGO:0090504410.017
negative regulation of protein maturationGO:1903318100.017
regulation of nitrogen compound metabolic processGO:00511712510.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
regulation of hormone secretionGO:004688320.016
spermatid differentiationGO:004851520.016
homeostatic processGO:00425921420.016
negative regulation of gene expressionGO:0010629650.016
regulation of positive chemotaxisGO:005092640.016
oxidation reduction processGO:0055114410.016
vitamin a metabolic processGO:000677610.016
negative regulation of proteolysisGO:0045861100.016
cellular aromatic compound metabolic processGO:00067252950.016
positive regulation of cytokine productionGO:000181920.016
intracellular signal transductionGO:0035556850.016
generation of neuronsGO:00486993850.016
regulation of hormone levelsGO:0010817210.015
fatty acid biosynthetic processGO:000663340.015
wound healingGO:0042060900.015
regulation of cell shapeGO:000836010.015
positive regulation of secretionGO:005104710.015
regenerationGO:0031099910.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
coagulationGO:0050817130.015
cellular component disassemblyGO:002241110.015
negative regulation of peptidase activityGO:0010466100.015
blood vessel developmentGO:00015682460.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
neural crest cell developmentGO:0014032620.015
fat soluble vitamin metabolic processGO:000677540.015
heart developmentGO:00075073130.015
cellular biosynthetic processGO:00442492860.015
stem cell differentiationGO:00488631170.015
cytoskeleton organizationGO:0007010960.015
negative regulation of sequestering of calcium ionGO:005128340.014
regulation of cellular protein catabolic processGO:190336210.014
multi organism processGO:00517041340.014
cellular nitrogen compound metabolic processGO:00346412900.014
regulation of immune system processGO:0002682340.014
carboxylic acid metabolic processGO:0019752220.014
biological adhesionGO:0022610400.014
regulation of localizationGO:00328791040.014
synaptic growth at neuromuscular junctionGO:005112420.014
regulation of developmental processGO:00507932470.014
regulation of jak stat cascadeGO:004642530.014
response to nutrientGO:000758430.014
protein polymerizationGO:005125840.014
modification dependent protein catabolic processGO:001994130.014
regulation of intracellular signal transductionGO:1902531570.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
cell surface receptor signaling pathwayGO:00071663250.014
regulation of proteolysisGO:0030162240.014
endocrine system developmentGO:0035270650.014
heart morphogenesisGO:00030071560.014
embryonic organ developmentGO:00485683810.014
regulation of metabolic processGO:00192223590.014
positive regulation of biological processGO:00485182530.013
rna metabolic processGO:00160702190.013
cellular catabolic processGO:0044248270.013
transportGO:00068102200.013
muscle cell differentiationGO:00426921390.013
nucleobase containing compound metabolic processGO:00061392740.013
positive regulation of cellular component biogenesisGO:004408930.013
cellular component biogenesisGO:00440851780.013
positive regulation of cell adhesionGO:004578510.013
negative regulation of metabolic processGO:0009892860.013
regulation of cellular ketone metabolic processGO:001056570.013
nephron morphogenesisGO:007202820.013
otic vesicle developmentGO:0071599420.013
mesenchymal cell developmentGO:0014031780.013
regulation of biosynthetic processGO:00098892500.012
female gonad developmentGO:000858540.012
hormone transportGO:000991420.012
muscle organ developmentGO:00075171010.012
regionalizationGO:00030022740.012
small molecule metabolic processGO:0044281770.012
regulation of neurogenesisGO:0050767870.012
vasculature developmentGO:00019442780.012
carboxylic acid catabolic processGO:004639530.012
regulation of nervous system developmentGO:0051960900.012
sensory organ developmentGO:00074233930.012
embryonic heart tube morphogenesisGO:00031431080.012
negative regulation of dna metabolic processGO:005105340.012
response to carbohydrateGO:000974330.012
cellular amine metabolic processGO:004410620.012
negative regulation of response to stimulusGO:00485851040.012
chemosensory behaviorGO:000763510.012
heart contractionGO:0060047710.012
adherens junction organizationGO:003433240.011
regulation of stem cell proliferationGO:007209120.011
carbohydrate biosynthetic processGO:001605110.011
cation transportGO:0006812810.011
response to hormoneGO:0009725480.011
epithelial cell developmentGO:0002064420.011
cellular process involved in reproduction in multicellular organismGO:0022412280.011
organic cyclic compound metabolic processGO:19013603010.011
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.011
secondary metabolic processGO:001974830.011
nucleic acid metabolic processGO:00903042440.011
extracellular matrix organizationGO:0030198270.011
taxisGO:00423301090.011
regulation of cell developmentGO:00602841000.011
negative regulation of multi organism processGO:004390130.011
angiogenesisGO:00015251580.011
regulation of stem cell differentiationGO:200073640.011
neural crest cell migrationGO:0001755420.011
regulation of protein ubiquitinationGO:003139630.010
carbohydrate homeostasisGO:003350010.010
regulation of cell activationGO:005086510.010
protein maturationGO:0051604120.010
embryonic organ morphogenesisGO:00485622740.010
positive regulation of cellular catabolic processGO:003133130.010
triglyceride homeostasisGO:007032820.010
development of primary female sexual characteristicsGO:004654540.010
inner ear developmentGO:00488391260.010
muscle tissue developmentGO:00605371100.010

pklr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.130
immune system diseaseDOID:291400.021
disease of metabolismDOID:001466700.015
hematopoietic system diseaseDOID:7400.011
cardiovascular system diseaseDOID:128700.010