Danio rerio

8 known processes

hadha

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit

(Aliases: im:7136067,cb1055,hadhaa,wu:fa14c08)

hadha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dicarboxylic acid metabolic processGO:004364810.488
carboxylic acid catabolic processGO:004639530.403
Mouse
agingGO:000756820.271
small molecule metabolic processGO:0044281770.264
Mouse
transmembrane transportGO:00550851200.211
organic acid catabolic processGO:001605430.196
Mouse
response to chemicalGO:00422213200.189
Mouse
fatty acid beta oxidationGO:000663510.182
Mouse
cellular lipid catabolic processGO:004424230.160
Mouse
organic acid metabolic processGO:0006082310.158
Mouse
heart developmentGO:00075073130.158
response to stressGO:00069502630.154
signal transductionGO:00071654550.154
carboxylic acid metabolic processGO:0019752220.134
Mouse
lipid oxidationGO:003444010.122
Mouse
neuron differentiationGO:00301823530.121
cellular catabolic processGO:0044248270.115
Mouse
organonitrogen compound metabolic processGO:1901564740.113
response to drugGO:004249330.113
response to copper ionGO:0046688130.104
apoptotic processGO:00069151160.097
organophosphate metabolic processGO:0019637370.094
single organism transportGO:00447652060.091
brain developmentGO:00074202930.089
purine ribonucleoside monophosphate catabolic processGO:000916940.089
alpha amino acid metabolic processGO:190160530.088
purine nucleoside monophosphate catabolic processGO:000912840.088
response to nutrientGO:000758430.088
response to transition metal nanoparticleGO:1990267280.088
heterocycle biosynthetic processGO:00181302150.088
ribonucleoside monophosphate catabolic processGO:000915840.084
determination of left right symmetryGO:00073681790.083
single organism localizationGO:19025782250.083
intracellular transportGO:0046907320.082
response to temperature stimulusGO:0009266150.080
lipid catabolic processGO:001604240.080
Mouse
adult behaviorGO:003053420.078
cellular nitrogen compound metabolic processGO:00346412900.078
neuron developmentGO:00486662620.077
larval developmentGO:000216420.077
Worm
response to organic substanceGO:00100331530.075
Mouse
hydrogen peroxide metabolic processGO:004274320.074
cellular amino acid biosynthetic processGO:000865220.074
embryo development ending in birth or egg hatchingGO:00097922710.072
Worm
small molecule catabolic processGO:004428230.069
Mouse
nitrogen compound metabolic processGO:00068073190.069
single organism metabolic processGO:00447102170.069
Mouse
oxoacid metabolic processGO:0043436310.068
Mouse
regulation of biosynthetic processGO:00098892500.067
cellular nitrogen compound biosynthetic processGO:00442712180.067
generation of neuronsGO:00486993850.067
positive regulation of biological processGO:00485182530.065
cellular amino acid metabolic processGO:000652070.064
regulation of cellular biosynthetic processGO:00313262450.064
rna metabolic processGO:00160702190.064
regulation of primary metabolic processGO:00800903110.063
monocarboxylic acid catabolic processGO:007232930.063
Mouse
protein localization to plasma membraneGO:007265910.062
specification of symmetryGO:00097992040.062
negative regulation of biological processGO:00485193040.061
organonitrogen compound biosynthetic processGO:1901566470.059
oxidation reduction processGO:0055114410.059
Mouse
cell part morphogenesisGO:00329902460.058
maintenance of locationGO:005123540.058
Worm
phosphatidylinositol 3 kinase signalingGO:001406520.056
biosynthetic processGO:00090582940.055
determination of bilateral symmetryGO:00098552040.055
cellular monovalent inorganic cation homeostasisGO:003000420.055
transportGO:00068102200.055
Worm
ion transportGO:00068111140.054
nucleoside monophosphate catabolic processGO:000912540.053
ion transmembrane transportGO:0034220910.053
organic substance biosynthetic processGO:19015762890.052
regulation of cellular carbohydrate metabolic processGO:001067540.051
cellular biosynthetic processGO:00442492860.051
cellular ketone metabolic processGO:0042180110.050
embryonic organ morphogenesisGO:00485622740.050
single organism biosynthetic processGO:0044711710.050
atp catabolic processGO:000620040.050
energy reserve metabolic processGO:000611220.049
sequestering of metal ionGO:005123830.049
cellular response to external stimulusGO:007149620.049
gtp catabolic processGO:000618420.049
cellular respirationGO:004533330.048
phosphorus metabolic processGO:00067931090.048
regulation of cell deathGO:00109411030.048
embryonic heart tube morphogenesisGO:00031431080.048
cell agingGO:000756920.047
cellular response to chemical stimulusGO:00708871570.047
cellular component biogenesisGO:00440851780.047
regulation of biological qualityGO:00650082630.047
Worm
response to starvationGO:004259450.047
head developmentGO:00603223030.045
central nervous system developmentGO:00074173870.044
nucleobase containing compound metabolic processGO:00061392740.044
regulation of nitrogen compound metabolic processGO:00511712510.044
organic cyclic compound metabolic processGO:19013603010.043
regulation of cytokine productionGO:000181730.043
cellular component morphogenesisGO:00329893360.043
gland developmentGO:00487321430.043
cell projection organizationGO:00300302840.041
cellular component assemblyGO:00226071700.041
phagocytosisGO:000690930.041
carbohydrate derivative metabolic processGO:1901135610.040
positive regulation of transportGO:005105020.039
organic cyclic compound biosynthetic processGO:19013622230.039
embryonic heart tube developmentGO:00350501330.039
response to abiotic stimulusGO:00096281220.038
single organism intracellular transportGO:1902582250.037
fatty acid transportGO:001590810.037
morphogenesis of an epitheliumGO:00020093330.037
regulation of nucleoside metabolic processGO:000911820.037
embryonic organ developmentGO:00485683810.037
cell morphogenesisGO:00009022890.036
regulation of metabolic processGO:00192223590.036
regulation of tube sizeGO:003515020.036
guanosine containing compound metabolic processGO:190106840.036
mitochondrion organizationGO:000700540.036
hormone biosynthetic processGO:004244630.035
cellular aromatic compound metabolic processGO:00067252950.035
nucleic acid templated transcriptionGO:00976591810.035
regulation of apoptotic processGO:0042981980.035
stem cell differentiationGO:00488631170.034
negative regulation of cellular processGO:00485232830.034
guanosine containing compound catabolic processGO:190106920.034
determination of heart left right asymmetryGO:00613711170.034
cellular macromolecule biosynthetic processGO:00346452240.033
lipid homeostasisGO:005508830.033
regulation of programmed cell deathGO:00430671010.032
phosphate containing compound metabolic processGO:00067961080.032
zymogen activationGO:003163830.032
nucleotide metabolic processGO:0009117280.032
ion homeostasisGO:0050801410.032
response to external stimulusGO:00096052640.031
regulation of cellular macromolecule biosynthetic processGO:20001122220.031
cellular response to topologically incorrect proteinGO:003596720.031
protein homooligomerizationGO:005126030.031
system processGO:00030081850.031
organelle organizationGO:00069962270.031
alcohol biosynthetic processGO:004616520.030
regulation of nucleotide catabolic processGO:003081120.030
response to coldGO:000940940.029
response to hydrogen peroxideGO:004254230.029
intestinal cholesterol absorptionGO:003029920.029
cellular component movementGO:00069283350.029
negative regulation of apoptotic processGO:0043066550.029
gtp metabolic processGO:004603940.029
nucleic acid metabolic processGO:00903042440.029
regulation of transmembrane transporter activityGO:002289820.029
response to inorganic substanceGO:0010035380.029
heart loopingGO:0001947940.029
cellular amide metabolic processGO:004360340.029
programmed cell deathGO:00125011190.028
regulation of cellular metabolic processGO:00313233200.028
lipid storageGO:001991510.028
Worm
circulatory system processGO:0003013870.028
inorganic ion transmembrane transportGO:0098660570.028
nucleobase containing small molecule metabolic processGO:0055086320.027
heart morphogenesisGO:00030071560.027
cell substrate adhesionGO:003158940.027
regulation of signalingGO:00230512350.027
cellular macromolecule metabolic processGO:00442603910.027
regulation of blood vessel sizeGO:005088020.027
response to metal ionGO:0010038340.027
regulation of muscle contractionGO:000693730.027
regulation of multicellular organism growthGO:004001440.026
establishment of protein localization to organelleGO:007259440.026
epithelial tube morphogenesisGO:00605621480.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
locomotionGO:00400113130.026
regulation of nucleobase containing compound metabolic processGO:00192192500.026
multicellular organism growthGO:003526440.026
regulation of signal transductionGO:00099662250.025
carbohydrate biosynthetic processGO:001605110.025
regulation of bindingGO:005109830.025
regulation of blood pressureGO:000821710.025
regulation of anatomical structure sizeGO:0090066330.025
response to glucocorticoidGO:005138410.025
establishment of localizationGO:00512342440.025
Worm
single organism nuclear importGO:190259330.025
cell deathGO:00082191210.025
purine nucleotide metabolic processGO:0006163270.025
cellular modified amino acid metabolic processGO:000657530.025
cell morphogenesis involved in neuron differentiationGO:00486671630.024
negative regulation of heart contractionGO:004582220.024
cellular localizationGO:0051641970.024
smooth muscle contractionGO:000693920.024
pole plasm assemblyGO:000731540.024
regulation of developmental processGO:00507932470.024
aromatic compound biosynthetic processGO:00194382170.024
blood circulationGO:0008015870.024
macromolecule biosynthetic processGO:00090592270.024
cellular response to nutrient levelsGO:003166920.023
protein targeting to nucleusGO:004474430.023
chemical homeostasisGO:0048878490.023
establishment of localization in cellGO:0051649770.023
cellular response to starvationGO:000926710.023
response to endogenous stimulusGO:0009719830.023
Mouse
response to vitamin b3GO:003355220.023
deathGO:00162651210.023
cellular response to organic substanceGO:00713101050.023
regulation of cellular ketone metabolic processGO:001056570.023
protein importGO:001703830.022
cell death in response to oxidative stressGO:003647320.022
fatty acid oxidationGO:001939510.022
Mouse
aromatic compound catabolic processGO:0019439150.022
hepaticobiliary system developmentGO:0061008980.022
mitochondrial transportGO:000683920.022
macromolecular complex subunit organizationGO:0043933740.022
rna localizationGO:000640340.022
regulation of cell communicationGO:00106462320.022
regulation of purine nucleotide catabolic processGO:003312120.022
positive regulation of cell adhesionGO:004578510.022
regulation of rho protein signal transductionGO:003502320.021
heterocycle metabolic processGO:00464832900.021
cation transportGO:0006812810.021
rna biosynthetic processGO:00327741810.021
catecholamine metabolic processGO:000658420.021
cell motilityGO:00488702440.021
positive regulation of map kinase activityGO:004340630.021
protein targeting to membraneGO:000661210.021
nucleoside phosphate metabolic processGO:0006753280.021
cation homeostasisGO:0055080330.021
ubiquitin dependent protein catabolic processGO:000651130.020
response to hormoneGO:0009725480.020
Mouse
regulation of gene expressionGO:00104682650.020
protein complex assemblyGO:0006461300.020
heart valve formationGO:000318840.020
response to oxidative stressGO:0006979110.020
cation transmembrane transportGO:0098655650.020
establishment of protein localization to plasma membraneGO:009000210.020
positive regulation of lipid metabolic processGO:004583410.020
nuclear importGO:005117030.020
purine ribonucleotide metabolic processGO:0009150270.020
catabolic processGO:0009056320.020
Mouse
inositol lipid mediated signalingGO:004801720.019
organic hydroxy compound transportGO:0015850140.019
regulation of ion transmembrane transporter activityGO:003241220.019
homeostatic processGO:00425921420.019
liver developmentGO:0001889960.019
membrane fusionGO:006102520.019
regulation of gtp catabolic processGO:003312420.019
regulation of protein bindingGO:004339330.019
regulation of gtpase activityGO:004308720.019
fatty acid catabolic processGO:000906210.019
Mouse
regulation of cellular amino acid metabolic processGO:000652100.019
negative regulation of signal transductionGO:0009968940.019
actin polymerization or depolymerizationGO:000815420.018
cellular amine metabolic processGO:004410620.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
electron transport chainGO:002290020.018
response to uvGO:000941130.018
cellular response to hypoxiaGO:007145610.018
tissue remodelingGO:004877140.018
negative regulation of cell communicationGO:0010648960.018
modification dependent protein catabolic processGO:001994130.018
regulation of cellular component organizationGO:0051128860.018
organic acid biosynthetic processGO:0016053120.018
regulation of cell projection assemblyGO:006049140.018
positive regulation of cellular catabolic processGO:003133130.018
cellular response to extracellular stimulusGO:003166820.018
cellular response to oxygen radicalGO:007145020.018
axonogenesisGO:00074091520.018
muscle cell differentiationGO:00426921390.018
cellular response to stressGO:0033554620.018
positive regulation of catabolic processGO:000989640.018
response to oxygen containing compoundGO:1901700550.018
Mouse
protein import into nucleusGO:000660630.018
cellular response to oxygen levelsGO:007145310.018
response to corticosteroidGO:003196010.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of fatty acid metabolic processGO:001921710.017
modification dependent macromolecule catabolic processGO:004363230.017
cellular transition metal ion homeostasisGO:004691630.017
cell migrationGO:00164772370.017
protein polymerizationGO:005125840.017
carboxylic acid biosynthetic processGO:0046394120.017
nucleobase containing compound biosynthetic processGO:00346542050.017
regenerationGO:0031099910.017
cell surface receptor signaling pathwayGO:00071663250.017
ribose phosphate metabolic processGO:0019693270.017
protein complex biogenesisGO:0070271300.017
phosphatidylinositol mediated signalingGO:004801520.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
proteasomal protein catabolic processGO:001049820.016
regulation of rac protein signal transductionGO:003502010.016
organic substance catabolic processGO:1901575280.016
Mouse
positive regulation of cytokine productionGO:000181920.016
axon developmentGO:00615641660.016
regulation of response to stimulusGO:00485832690.016
monocarboxylic acid biosynthetic processGO:0072330120.016
negative regulation of cytokine productionGO:000181810.016
negative regulation of sequestering of calcium ionGO:005128340.016
muscle structure developmentGO:00610611960.016
regulation of cellular amine metabolic processGO:003323800.016
cellular carbohydrate metabolic processGO:004426240.016
organic substance transportGO:0071702580.016
removal of superoxide radicalsGO:001943020.015
striated muscle cell differentiationGO:00511461290.015
positive regulation of nucleoside metabolic processGO:004597910.015
organic anion transportGO:0015711150.015
cellular response to reactive oxygen speciesGO:003461420.015
amine metabolic processGO:000930820.015
reproductionGO:0000003400.015
neuron projection morphogenesisGO:00488121610.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
peptide metabolic processGO:000651810.015
regulation of rna metabolic processGO:00512522240.015
cell projection morphogenesisGO:00488582440.015
regulation of transporter activityGO:003240920.015
development of primary female sexual characteristicsGO:004654540.015
regulation of growthGO:0040008420.015
vasculature developmentGO:00019442780.015
protein oligomerizationGO:005125970.015
synaptic growth at neuromuscular junctionGO:005112420.015
multi organism processGO:00517041340.015
regulation of localizationGO:00328791040.014
regulation of lyase activityGO:0051339120.014
regulation of dna templated transcription in response to stressGO:004362000.014
localization of cellGO:00516742440.014
regulation of cardiac muscle contractionGO:005511720.014
mononuclear cell proliferationGO:003294310.014
cytokinesisGO:000091030.014
protein localization to nucleusGO:003450430.014
heart processGO:0003015710.014
catechol containing compound metabolic processGO:000971220.014
regulation of ras gtpase activityGO:003231820.014
lipid metabolic processGO:0006629520.014
Mouse
regulation of sequestering of calcium ionGO:005128240.014
response to glucoseGO:000974930.014
nucleocytoplasmic transportGO:000691340.014
cytokinetic processGO:003250620.014
neuron projection developmentGO:00311751800.014
positive regulation of signal transductionGO:0009967560.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
single organism cellular localizationGO:1902580460.014
negative regulation of blood circulationGO:190352320.014
mesenchymal cell differentiationGO:0048762870.014
response to lipidGO:0033993600.014
regulation of cytoplasmic transportGO:190364940.014
ovulation cycleGO:004269820.014
multicellular organismal response to stressGO:003355520.014
extrinsic apoptotic signaling pathwayGO:009719130.014
positive regulation of cellular processGO:00485222010.014
regulation of circadian rhythmGO:004275240.014
regulation of myotube differentiationGO:001083020.014
long chain fatty acid transportGO:001590910.014
cytoplasm organizationGO:000702840.014
transcription dna templatedGO:00063511810.014
calcium ion transport into cytosolGO:006040230.014
regulation of protein complex assemblyGO:004325430.013
negative regulation of multicellular organismal processGO:0051241690.013
positive regulation of metabolic processGO:00098931080.013
multicellular organismal homeostasisGO:0048871290.013
anion transportGO:0006820380.013
positive regulation of striated muscle cell differentiationGO:005115510.013
gene expressionGO:00104672520.013
entrainment of circadian clockGO:000964920.013
response to topologically incorrect proteinGO:003596620.013
regulation of cell shapeGO:000836010.013
regulation of multicellular organismal processGO:00512392770.013
negative regulation of catabolic processGO:000989530.013
positive regulation of cell communicationGO:0010647560.013
sequestering of calcium ionGO:005120830.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.013
regulation of circadian sleep wake cycleGO:004274910.013
regulation of neurotransmitter transportGO:005158810.013
spermatid differentiationGO:004851520.013
regulation of production of molecular mediator of immune responseGO:000270010.013
membrane hyperpolarizationGO:006008110.013
long chain fatty acid metabolic processGO:000167610.013
muscle tissue developmentGO:00605371100.013
respiratory electron transport chainGO:002290420.013
release of sequestered calcium ion into cytosolGO:005120930.013
carbohydrate derivative biosynthetic processGO:1901137430.013
leukocyte proliferationGO:007066110.013
regulation of rna biosynthetic processGO:20011412130.012
membrane invaginationGO:001032410.012
cellular protein catabolic processGO:004425740.012
transmission of nerve impulseGO:0019226190.012
homeostasis of number of cellsGO:0048872620.012
positive regulation of gliogenesisGO:001401520.012
negative regulation of response to stimulusGO:00485851040.012
production of molecular mediator of immune responseGO:000244020.012
regulation of striated muscle contractionGO:000694220.012
intracellular mrna localizationGO:000829810.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.012
regulation of protein transportGO:005122330.012
circadian sleep wake cycle sleepGO:005080210.012
branching morphogenesis of a nerveGO:004875540.012
ameboidal type cell migrationGO:00016671430.012
collagen metabolic processGO:003296320.012
regulation of reproductive processGO:200024140.012
regulation of heart contractionGO:0008016320.012
regulation of membrane potentialGO:0042391230.012
astrocyte differentiationGO:004870810.012
organic hydroxy compound metabolic processGO:1901615160.012
activation of mapk activityGO:000018730.012
tube morphogenesisGO:00352393490.012
inorganic cation transmembrane transportGO:0098662500.012
regulation of response to extracellular stimulusGO:003210410.012
response to hypoxiaGO:0001666250.012
heart contractionGO:0060047710.012
regulation of purine nucleotide metabolic processGO:1900542170.012
positive regulation of response to stimulusGO:0048584800.012
cell morphogenesis involved in differentiationGO:00009041950.012
response to foodGO:003209410.012
regulation of circadian sleep wake cycle sleepGO:004518710.012
cardiocyte differentiationGO:0035051440.012
regulation of multicellular organismal developmentGO:20000262230.012
response to unfolded proteinGO:000698620.012
regulation of transcription dna templatedGO:00063552130.012
ras protein signal transductionGO:000726570.012
phagocytosis engulfmentGO:000691110.011
regulation of cell motilityGO:2000145460.011
oocyte anterior posterior axis specificationGO:000731440.011
regulation of sodium ion transmembrane transportGO:190230510.011
metal ion homeostasisGO:0055065260.011
cellular response to drugGO:003569010.011
response to organic cyclic compoundGO:0014070510.011
negative regulation of programmed cell deathGO:0043069580.011
action potentialGO:0001508190.011
regulation of endopeptidase activityGO:0052548230.011
positive regulation of cellular metabolic processGO:0031325940.011
meiotic cell cycle processGO:190304630.011
circadian sleep wake cycle processGO:002241020.011
regulation of response to nutrient levelsGO:003210710.011
negative regulation of cell deathGO:0060548600.011
organophosphate biosynthetic processGO:0090407230.011
regulation of reactive oxygen species metabolic processGO:200037720.011
single organism membrane fusionGO:004480120.011
regulation of skeletal muscle tissue developmentGO:004864140.011
positive regulation of nucleotide catabolic processGO:003081310.011
regulation of hormone secretionGO:004688320.011
outflow tract morphogenesisGO:000315110.011
retinoic acid receptor signaling pathwayGO:0048384160.011
lymphocyte proliferationGO:004665110.011
actin filament based movementGO:003004810.011
camera type eye developmentGO:00430102220.011
antimicrobial humoral responseGO:001973020.011
regulation of cell activationGO:005086510.011
female gonad developmentGO:000858540.011
tissue homeostasisGO:0001894250.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
energy derivation by oxidation of organic compoundsGO:001598050.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
protein complex disassemblyGO:004324110.011
regulation of metal ion transportGO:001095940.011
extracellular matrix organizationGO:0030198270.011
neuron projection guidanceGO:0097485860.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of protein catabolic processGO:004217610.011
polyol metabolic processGO:001975110.010
regulation of molecular functionGO:0065009700.010
hormone secretionGO:004687920.010
response to hexoseGO:000974630.010
small molecule biosynthetic processGO:0044283160.010
positive regulation of gtp catabolic processGO:003312610.010
blood vessel developmentGO:00015682460.010
regulation of intracellular protein transportGO:003315730.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
positive regulation of cellular component biogenesisGO:004408930.010
transcription from rna polymerase ii promoterGO:0006366800.010
response to vitaminGO:003327330.010
regulation of systemic arterial blood pressureGO:000307310.010
female sex differentiationGO:004666040.010
regulation of lipid catabolic processGO:005099420.010

hadha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.128
disease of metabolismDOID:001466700.107
inherited metabolic disorderDOID:65500.107
nervous system diseaseDOID:86300.043
sensory system diseaseDOID:005015500.019
musculoskeletal system diseaseDOID:1700.019
disease of cellular proliferationDOID:1456600.014
eye and adnexa diseaseDOID:149200.014
eye diseaseDOID:561400.014
cancerDOID:16200.012