Danio rerio

0 known processes

pola2

polymerase (DNA directed), alpha 2

(Aliases: zgc:77841,wu:fb48f05,zgc:56124)

pola2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:000630230.852
double strand break repair via homologous recombinationGO:000072410.814
mitotic recombinationGO:000631220.594
recombinational repairGO:000072510.462
cellular nitrogen compound metabolic processGO:00346412900.400
atp catabolic processGO:000620040.384
embryo development ending in birth or egg hatchingGO:00097922710.383
organic cyclic compound metabolic processGO:19013603010.365
nucleic acid metabolic processGO:00903042440.352
purine nucleoside monophosphate catabolic processGO:000912840.350
nucleoside monophosphate catabolic processGO:000912540.337
regulation of dna recombinationGO:000001820.333
response to stressGO:00069502630.309
cellular biosynthetic processGO:00442492860.308
ribonucleoside monophosphate catabolic processGO:000915840.288
biosynthetic processGO:00090582940.285
meiosis iGO:000712710.280
dna repairGO:000628160.245
cellular aromatic compound metabolic processGO:00067252950.242
meiotic nuclear divisionGO:000712640.228
nucleobase containing compound metabolic processGO:00061392740.217
organic cyclic compound biosynthetic processGO:19013622230.202
cellular macromolecule biosynthetic processGO:00346452240.197
cellular response to dna damage stimulusGO:0006974240.187
nitrogen compound metabolic processGO:00068073190.185
organic substance biosynthetic processGO:19015762890.171
heterocycle metabolic processGO:00464832900.158
dna metabolic processGO:0006259270.157
regulation of nitrogen compound metabolic processGO:00511712510.153
cellular nitrogen compound biosynthetic processGO:00442712180.146
dna biosynthetic processGO:007189730.146
purine ribonucleoside monophosphate catabolic processGO:000916940.141
meiotic cell cycle processGO:190304630.138
multicellular organism growthGO:003526440.126
aromatic compound biosynthetic processGO:00194382170.119
locomotionGO:00400113130.117
organonitrogen compound metabolic processGO:1901564740.116
reciprocal meiotic recombinationGO:000713110.116
response to alkaloidGO:004327920.112
regulation of primary metabolic processGO:00800903110.112
response to chemicalGO:00422213200.111
cellular macromolecule metabolic processGO:00442603910.109
meiotic chromosome segregationGO:004513230.106
positive regulation of dna metabolic processGO:005105410.106
heterocycle biosynthetic processGO:00181302150.103
organelle organizationGO:00069962270.101
telomere maintenanceGO:000072310.100
regulation of multicellular organism growthGO:004001440.099
chromosome organizationGO:0051276310.099
single organism organelle organizationGO:19025891990.093
negative regulation of cellular processGO:00485232830.090
larval developmentGO:000216420.089
telomere organizationGO:003220010.088
cellular response to radiationGO:007147840.087
regulation of transcription dna templatedGO:00063552130.086
hatchingGO:003518840.085
homeostatic processGO:00425921420.082
macromolecule biosynthetic processGO:00090592270.081
rna metabolic processGO:00160702190.080
dna catabolic processGO:000630810.079
regulation of nucleobase containing compound metabolic processGO:00192192500.075
agingGO:000756820.074
regulation of macromolecule metabolic processGO:00602553170.073
positive regulation of nitrogen compound metabolic processGO:0051173690.071
small molecule metabolic processGO:0044281770.071
regulation of cellular amine metabolic processGO:003323800.069
protein acetylationGO:000647320.069
positive regulation of histone modificationGO:003105810.068
amine metabolic processGO:000930820.067
histone h3 k4 methylationGO:005156820.066
cellular response to stressGO:0033554620.066
oxoacid metabolic processGO:0043436310.066
mitotic dna damage checkpointGO:004477340.066
dna recombinationGO:000631050.066
chromosome organization involved in meiosisGO:007019210.065
rna biosynthetic processGO:00327741810.064
pyrimidine containing compound metabolic processGO:007252730.064
cellular amine metabolic processGO:004410620.064
regulation of cellular ketone metabolic processGO:001056570.063
regulation of cellular amino acid metabolic processGO:000652100.062
carboxylic acid metabolic processGO:0019752220.061
regulation of biological qualityGO:00650082630.060
cellular amino acid metabolic processGO:000652070.059
mitotic dna integrity checkpointGO:004477440.058
response to uvGO:000941130.057
organic acid metabolic processGO:0006082310.057
regulation of cellular metabolic processGO:00313233200.056
signal transduction by p53 class mediatorGO:0072331130.056
lipid storageGO:001991510.054
mitotic g2 dna damage checkpointGO:000709530.054
positive regulation of macromolecule metabolic processGO:0010604930.053
cellular ketone metabolic processGO:0042180110.052
positive regulation of chromatin modificationGO:190331010.051
regulation of nucleic acid templated transcriptionGO:19035062130.051
response to organic substanceGO:00100331530.048
regulation of biosynthetic processGO:00098892500.048
maintenance of locationGO:005123540.047
positive regulation of cellular amino acid metabolic processGO:004576400.047
protein acylationGO:004354330.045
cellular component disassemblyGO:002241110.045
positive regulation of biological processGO:00485182530.045
response to drugGO:004249330.045
single organism metabolic processGO:00447102170.044
positive regulation of nucleobase containing compound metabolic processGO:0045935690.044
cell cycle g2 m phase transitionGO:004483940.043
regulation of cellular macromolecule biosynthetic processGO:20001122220.043
regulation of macromolecule biosynthetic processGO:00105562250.043
phosphate containing compound metabolic processGO:00067961080.042
response to radiationGO:0009314510.041
peptidyl lysine acetylationGO:001839420.041
cytokinesisGO:000091030.041
regulation of dna templated transcription in response to stressGO:004362000.040
cellular protein modification processGO:00064641000.040
growthGO:00400071740.039
internal protein amino acid acetylationGO:000647520.039
production of molecular mediator of immune responseGO:000244020.039
regulation of rna metabolic processGO:00512522240.039
negative regulation of biological processGO:00485193040.039
immune system processGO:00023762410.038
organism emergence from protective structureGO:007168440.038
carbohydrate derivative metabolic processGO:1901135610.037
nucleobase containing compound biosynthetic processGO:00346542050.037
transcription from rna polymerase ii promoterGO:0006366800.036
regulation of rna biosynthetic processGO:20011412130.036
positive regulation of cellular amine metabolic processGO:003324000.035
regulation of cellular biosynthetic processGO:00313262450.035
negative regulation of dna metabolic processGO:005105340.035
nucleic acid templated transcriptionGO:00976591810.034
developmental growthGO:00485891660.034
mitotic g2 m transition checkpointGO:004481830.034
apoptotic processGO:00069151160.033
reproductive processGO:0022414400.033
microtubule based processGO:0007017600.032
cellular response to external stimulusGO:007149620.031
reproductionGO:0000003400.031
deathGO:00162651210.031
gene silencingGO:001645840.031
positive regulation of rna biosynthetic processGO:1902680570.030
internal peptidyl lysine acetylationGO:001839320.030
regulation of protein complex assemblyGO:004325430.030
somatic cell dna recombinationGO:001644410.030
regulation of dna metabolic processGO:0051052110.030
cellular response to organic substanceGO:00713101050.029
sensory organ developmentGO:00074233930.029
establishment of protein localization to organelleGO:007259440.029
single organism biosynthetic processGO:0044711710.028
developmental programmed cell deathGO:001062340.028
response to abiotic stimulusGO:00096281220.028
programmed cell deathGO:00125011190.027
cell motilityGO:00488702440.027
reciprocal dna recombinationGO:003582510.027
transcription dna templatedGO:00063511810.027
dna templated transcription initiationGO:000635210.027
establishment of localizationGO:00512342440.027
male meiosisGO:000714020.027
transportGO:00068102200.026
g2 dna damage checkpointGO:003157230.026
cell proliferationGO:0008283800.026
immunoglobulin mediated immune responseGO:001606430.026
positive regulation of metabolic processGO:00098931080.026
positive regulation of rna metabolic processGO:0051254590.025
g2 m transition of mitotic cell cycleGO:000008640.025
positive regulation of gene expressionGO:0010628710.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.025
specification of axis polarityGO:006500140.024
macromolecule modificationGO:00434121110.024
immune system developmentGO:00025201910.024
cellular protein complex assemblyGO:0043623190.024
regulation of metabolic processGO:00192223590.024
gene expressionGO:00104672520.024
phosphorus metabolic processGO:00067931090.024
protein complex biogenesisGO:0070271300.024
negative regulation of nuclear divisionGO:005178430.023
cellular component movementGO:00069283350.023
regulation of gene expression epigeneticGO:0040029110.023
intrinsic apoptotic signaling pathwayGO:0097193200.023
mitotic cell cycleGO:0000278640.023
camera type eye developmentGO:00430102220.022
peptidyl serine phosphorylationGO:001810510.022
organelle fissionGO:0048285230.022
cell morphogenesisGO:00009022890.022
cellular component morphogenesisGO:00329893360.022
b cell activationGO:004211320.022
immunoglobulin productionGO:000237710.021
multi organism processGO:00517041340.021
anatomical structure homeostasisGO:0060249360.021
intracellular signal transductionGO:0035556850.021
atp metabolic processGO:004603450.021
deoxyribonucleotide metabolic processGO:000926210.020
regulation of protein catabolic processGO:004217610.020
peptidyl serine modificationGO:001820920.020
macromolecular complex subunit organizationGO:0043933740.020
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.020
positive regulation of cellular metabolic processGO:0031325940.020
lymphocyte activationGO:0046649100.020
developmental process involved in reproductionGO:0003006270.020
b cell mediated immunityGO:001972430.019
regulation of microtubule cytoskeleton organizationGO:007050730.019
cellular response to light stimulusGO:007148240.019
mitotic cell cycle processGO:1903047480.019
chromatin organizationGO:0006325220.019
organophosphate metabolic processGO:0019637370.019
female gamete generationGO:0007292140.019
rna localizationGO:000640340.019
nucleoside monophosphate metabolic processGO:000912360.019
response to organic cyclic compoundGO:0014070510.018
aromatic compound catabolic processGO:0019439150.018
negative regulation of nucleobase containing compound metabolic processGO:0045934590.018
nucleobase containing compound catabolic processGO:0034655150.018
rna catabolic processGO:000640170.018
cell cycle processGO:0022402530.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
regulation of response to stimulusGO:00485832690.018
dicarboxylic acid metabolic processGO:004364810.018
negative regulation of intracellular transportGO:003238730.018
fertilizationGO:000956630.018
system processGO:00030081850.018
adult behaviorGO:003053420.018
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
signal transductionGO:00071654550.017
nuclear transportGO:005116940.017
regulation of mitotic cell cycleGO:0007346250.017
multicellular organism reproductionGO:0032504350.017
leukocyte proliferationGO:007066110.017
intra s dna damage checkpointGO:003157310.017
nucleobase containing small molecule metabolic processGO:0055086320.017
cellular response to chemical stimulusGO:00708871570.017
chromatin modificationGO:0016568210.017
regulation of reactive oxygen species metabolic processGO:200037720.017
mitotic cell cycle embryonicGO:004544820.017
cellular component assemblyGO:00226071700.017
protein polyubiquitinationGO:000020940.017
nucleotide metabolic processGO:0009117280.017
female meiotic divisionGO:000714320.017
neurological system processGO:0050877620.016
cell migrationGO:00164772370.016
cell cycleGO:0007049930.016
positive regulation of biosynthetic processGO:0009891680.016
protein metabolic processGO:00195381830.016
protein polymerizationGO:005125840.016
ribonucleoside monophosphate metabolic processGO:000916150.016
protein complex assemblyGO:0006461300.016
regulation of response to stressGO:0080134360.016
positive regulation of macromolecule biosynthetic processGO:0010557590.016
carbohydrate derivative biosynthetic processGO:1901137430.015
response to external stimulusGO:00096052640.015
response to light stimulusGO:0009416460.015
ribonucleotide metabolic processGO:0009259270.015
rna export from nucleusGO:000640510.015
blood vessel morphogenesisGO:00485142160.015
camera type eye morphogenesisGO:00485931080.015
regulation of bindingGO:005109830.015
cellular catabolic processGO:0044248270.015
cellular response to organic cyclic compoundGO:0071407380.015
organic cyclic compound catabolic processGO:1901361150.015
positive regulation of protein complex assemblyGO:003133420.015
positive regulation of leukocyte mediated immunityGO:000270510.015
macromolecular complex assemblyGO:0065003350.015
negative regulation of biosynthetic processGO:0009890550.015
regulation of establishment of protein localizationGO:007020140.015
nucleotide biosynthetic processGO:0009165210.014
positive regulation of catabolic processGO:000989640.014
centrosome organizationGO:005129710.014
regulation of programmed cell deathGO:00430671010.014
regulation of gene expressionGO:00104682650.014
cognitionGO:005089010.014
nucleocytoplasmic transportGO:000691340.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
protein stabilizationGO:005082120.014
single organism reproductive processGO:0044702400.014
chemosensory behaviorGO:000763510.014
positive regulation of chromosome organizationGO:200125210.014
behaviorGO:0007610740.014
phosphorylationGO:0016310690.014
vasculature developmentGO:00019442780.014
regulation of cell proliferationGO:0042127370.014
muscle structure developmentGO:00610611960.014
positive regulation of transcription dna templatedGO:0045893570.014
cellular component biogenesisGO:00440851780.013
neuron projection morphogenesisGO:00488121610.013
retina development in camera type eyeGO:00600411460.013
response to ionizing radiationGO:001021260.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
chromosome segregationGO:0007059120.013
rna transportGO:005065820.013
maintenance of dna repeat elementsGO:004357020.013
response to endogenous stimulusGO:0009719830.013
regulation of cell cycleGO:0051726520.013
methylationGO:0032259220.013
peptidyl threonine phosphorylationGO:001810710.012
epithelium migrationGO:0090132250.012
purine ribonucleotide metabolic processGO:0009150270.012
eye developmentGO:00016542770.012
central nervous system developmentGO:00074173870.012
cell deathGO:00082191210.012
lymphocyte proliferationGO:004665110.012
sister chromatid cohesionGO:000706220.012
cell part morphogenesisGO:00329902460.012
regulation of developmental processGO:00507932470.012
cytoskeleton organizationGO:0007010960.012
organic substance catabolic processGO:1901575280.012
positive regulation of cellular biosynthetic processGO:0031328680.012
peptidyl threonine modificationGO:001821010.012
regulation of stem cell proliferationGO:007209120.012
regulation of cell cycle phase transitionGO:190198780.012
positive regulation of nuclease activityGO:003207510.012
protein modification processGO:00362111000.011
oocyte maturationGO:000155640.011
multicellular organismal reproductive processGO:0048609350.011
positive regulation of cytokine productionGO:000181920.011
cellular macromolecular complex assemblyGO:0034622240.011
female gonad developmentGO:000858540.011
cellular localizationGO:0051641970.011
modification dependent macromolecule catabolic processGO:004363230.011
mononuclear cell proliferationGO:003294310.011
regulation of protein import into nucleusGO:004230620.011
regulation of nucleocytoplasmic transportGO:004682220.011
non recombinational repairGO:000072620.011
macromolecular complex disassemblyGO:003298410.011
dna templated transcription elongationGO:000635430.011
heterocycle catabolic processGO:0046700150.011
g1 s transition of mitotic cell cycleGO:000008210.011
tissue remodelingGO:004877140.011
germ cell developmentGO:0007281220.011
lipid homeostasisGO:005508830.011
regulation of cell cycle g2 m phase transitionGO:190274940.011
nuclear importGO:005117030.011
regulation of mitosisGO:000708890.011
negative regulation of macromolecule metabolic processGO:0010605760.011
macromolecule catabolic processGO:0009057150.011
double strand break repair via nonhomologous end joiningGO:000630310.011
histone phosphorylationGO:001657220.010
negative regulation of cell cycle phase transitionGO:190198850.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
regulation of mitotic cell cycle phase transitionGO:190199080.010
pyrimidine containing compound biosynthetic processGO:007252820.010
cellular protein metabolic processGO:00442671290.010
gtp catabolic processGO:000618420.010
cell morphogenesis involved in differentiationGO:00009041950.010
catabolic processGO:0009056320.010
intracellular mrna localizationGO:000829810.010
regulation of dna replicationGO:000627530.010
zymogen activationGO:003163830.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
covalent chromatin modificationGO:0016569200.010
microtubule cytoskeleton organization involved in mitosisGO:190285010.010

pola2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.132
disease of cellular proliferationDOID:1456600.086
cancerDOID:16200.086
organ system cancerDOID:005068600.086
thoracic cancerDOID:509300.045
disease of metabolismDOID:001466700.019
breast cancerDOID:161200.018
inherited metabolic disorderDOID:65500.017
tauopathyDOID:68000.013
neurodegenerative diseaseDOID:128900.013
nervous system diseaseDOID:86300.013
central nervous system diseaseDOID:33100.013
gastrointestinal system cancerDOID:311900.013
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013