Danio rerio

0 known processes

cx44.2

connexin 44.2

(Aliases: etID18867.6,wu:fk18g12,fk18g12)

cx44.2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
specification of symmetryGO:00097992040.176
determination of bilateral symmetryGO:00098552040.159
determination of left right symmetryGO:00073681790.141
determination of heart left right asymmetryGO:00613711170.127
cellular macromolecule metabolic processGO:00442603910.124
nitrogen compound metabolic processGO:00068073190.110
regulation of signal transductionGO:00099662250.097
larval developmentGO:000216420.096
nucleic acid metabolic processGO:00903042440.094
negative regulation of cellular processGO:00485232830.093
cell migrationGO:00164772370.088
regulation of response to stimulusGO:00485832690.085
heterocycle metabolic processGO:00464832900.078
organic cyclic compound metabolic processGO:19013603010.076
cell surface receptor signaling pathwayGO:00071663250.075
embryonic heart tube developmentGO:00350501330.073
heart developmentGO:00075073130.072
negative regulation of biological processGO:00485193040.071
signal transductionGO:00071654550.070
heart morphogenesisGO:00030071560.070
nucleobase containing compound metabolic processGO:00061392740.069
embryonic organ developmentGO:00485683810.067
embryonic heart tube morphogenesisGO:00031431080.067
regionalizationGO:00030022740.065
cellular nitrogen compound metabolic processGO:00346412900.065
cellular nitrogen compound biosynthetic processGO:00442712180.065
organic substance biosynthetic processGO:19015762890.064
hemopoiesisGO:00300971830.064
heart loopingGO:0001947940.063
localization of cellGO:00516742440.061
cellular biosynthetic processGO:00442492860.061
chordate embryonic developmentGO:00430092710.060
immune system developmentGO:00025201910.059
immune system processGO:00023762410.059
regulation of transcription from rna polymerase ii promoterGO:00063571140.058
regulation of signalingGO:00230512350.057
response to external stimulusGO:00096052640.057
gene expressionGO:00104672520.056
maintenance of locationGO:005123540.056
rna metabolic processGO:00160702190.056
organic cyclic compound biosynthetic processGO:19013622230.055
aromatic compound biosynthetic processGO:00194382170.055
regulation of nucleobase containing compound metabolic processGO:00192192500.054
macromolecule biosynthetic processGO:00090592270.052
cellular component assemblyGO:00226071700.052
regulation of primary metabolic processGO:00800903110.052
response to stressGO:00069502630.051
epithelial tube morphogenesisGO:00605621480.051
tube morphogenesisGO:00352393490.051
cellular aromatic compound metabolic processGO:00067252950.051
locomotionGO:00400113130.051
cellular component movementGO:00069283350.050
single organism organelle organizationGO:19025891990.049
cell motilityGO:00488702440.048
transportGO:00068102200.047
agingGO:000756820.047
transcription from rna polymerase ii promoterGO:0006366800.047
nucleic acid templated transcriptionGO:00976591810.047
regulation of nitrogen compound metabolic processGO:00511712510.046
positive regulation of transportGO:005105020.046
cellular macromolecule biosynthetic processGO:00346452240.046
biosynthetic processGO:00090582940.046
mitochondrion organizationGO:000700540.045
regulation of cellular macromolecule biosynthetic processGO:20001122220.044
morphogenesis of an epitheliumGO:00020093330.044
nucleobase containing compound biosynthetic processGO:00346542050.044
rna biosynthetic processGO:00327741810.044
guanosine containing compound metabolic processGO:190106840.044
cellular protein modification processGO:00064641000.044
proteolysis involved in cellular protein catabolic processGO:005160330.044
regulation of cell communicationGO:00106462320.043
positive regulation of biological processGO:00485182530.043
stem cell maintenanceGO:001982740.042
single organism transportGO:00447652060.041
guanosine containing compound catabolic processGO:190106920.041
embryonic organ morphogenesisGO:00485622740.041
regulation of nucleic acid templated transcriptionGO:19035062130.040
digestive tract morphogenesisGO:00485462310.040
heterocycle biosynthetic processGO:00181302150.039
macromolecule localizationGO:0033036540.039
ameboidal type cell migrationGO:00016671430.039
cellular response to external stimulusGO:007149620.039
embryo development ending in birth or egg hatchingGO:00097922710.038
response to nutrientGO:000758430.038
positive regulation of catabolic processGO:000989640.038
regulation of rna metabolic processGO:00512522240.037
neuroblast proliferationGO:000740520.037
cell migration involved in gastrulationGO:0042074790.037
regulation of cellular metabolic processGO:00313233200.037
transcription dna templatedGO:00063511810.037
regulation of metabolic processGO:00192223590.037
regulation of skeletal muscle tissue developmentGO:004864140.037
establishment of localizationGO:00512342440.037
negative regulation of protein phosphorylationGO:000193340.037
cellular protein catabolic processGO:004425740.036
gland developmentGO:00487321430.036
blood vessel developmentGO:00015682460.036
positive regulation of cellular catabolic processGO:003133130.036
gtp metabolic processGO:004603940.035
organelle organizationGO:00069962270.035
head developmentGO:00603223030.035
regulation of macromolecule biosynthetic processGO:00105562250.035
autophagyGO:000691440.035
regulation of cell activationGO:005086510.035
amine metabolic processGO:000930820.035
regulation of gene expressionGO:00104682650.034
organonitrogen compound metabolic processGO:1901564740.034
organic acid metabolic processGO:0006082310.033
skeletal system developmentGO:00015011810.033
negative regulation of response to stimulusGO:00485851040.033
regulation of transcription dna templatedGO:00063552130.033
digestive system developmentGO:00551232890.033
digestive tract developmentGO:00485652650.033
regulation of developmental processGO:00507932470.033
eye developmentGO:00016542770.032
regulation of rna biosynthetic processGO:20011412130.032
stem cell divisionGO:001714510.032
gtp catabolic processGO:000618420.032
positive regulation of cell cycleGO:004578730.032
gastrulationGO:00073692080.032
regulation of bindingGO:005109830.031
modification dependent macromolecule catabolic processGO:004363230.031
phagocytosisGO:000690930.031
cellular response to extracellular stimulusGO:003166820.030
sensory organ developmentGO:00074233930.030
central nervous system developmentGO:00074173870.030
germ line stem cell maintenanceGO:003071820.030
cellular amine metabolic processGO:004410620.030
lipid storageGO:001991510.029
hepaticobiliary system developmentGO:0061008980.029
regulation of biosynthetic processGO:00098892500.029
enzyme linked receptor protein signaling pathwayGO:00071671060.029
positive regulation of muscle organ developmentGO:004863610.029
cellular ketone metabolic processGO:0042180110.029
system processGO:00030081850.029
regulation of cellular amine metabolic processGO:003323800.029
response to chemicalGO:00422213200.029
dorsal ventral pattern formationGO:00099531250.029
cellular localizationGO:0051641970.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
cytokinesisGO:000091030.028
regulation of cellular biosynthetic processGO:00313262450.028
ubiquitin dependent protein catabolic processGO:000651130.028
regulation of macromolecule metabolic processGO:00602553170.028
regulation of cell deathGO:00109411030.027
oxoacid metabolic processGO:0043436310.027
single organism metabolic processGO:00447102170.027
response to abiotic stimulusGO:00096281220.027
positive regulation of cell activationGO:005086710.027
regulation of cell differentiationGO:00455951420.027
single organism localizationGO:19025782250.026
negative regulation of nuclear divisionGO:005178430.026
carboxylic acid metabolic processGO:0019752220.026
regulation of nucleoside metabolic processGO:000911820.025
exocytosisGO:000688710.025
somite developmentGO:0061053960.025
cell proliferationGO:0008283800.025
cell morphogenesisGO:00009022890.025
negative regulation of signalingGO:0023057960.025
extrinsic apoptotic signaling pathwayGO:009719130.025
urogenital system developmentGO:0001655970.025
cell cycle g1 s phase transitionGO:004484310.025
regulation of reproductive processGO:200024140.024
response to carbohydrateGO:000974330.024
cilium morphogenesisGO:0060271850.024
developmental programmed cell deathGO:001062340.024
heart joggingGO:0003146400.024
camera type eye developmentGO:00430102220.024
somitogenesisGO:0001756870.024
regulation of establishment of protein localizationGO:007020140.024
cellular component biogenesisGO:00440851780.024
anterior posterior pattern specificationGO:00099521520.023
response to monosaccharideGO:003428430.023
homeostatic processGO:00425921420.023
regulation of cytokine productionGO:000181730.023
apoptotic processGO:00069151160.023
stem cell developmentGO:0048864820.023
organelle assemblyGO:00709251100.022
mitotic cell cycleGO:0000278640.022
modification dependent protein catabolic processGO:001994130.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
regulation of purine nucleotide catabolic processGO:003312120.022
chemosensory behaviorGO:000763510.022
cellular response to chemical stimulusGO:00708871570.022
mononuclear cell proliferationGO:003294310.022
blood vessel morphogenesisGO:00485142160.021
cellular protein metabolic processGO:00442671290.021
germ line stem cell divisionGO:004207810.021
brain developmentGO:00074202930.021
convergent extensionGO:00600261180.021
cellular amino acid metabolic processGO:000652070.021
cellular response to nutrient levelsGO:003166920.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
regulation of metal ion transportGO:001095940.021
cellular component morphogenesisGO:00329893360.021
kidney developmentGO:0001822920.021
lateral inhibitionGO:004633110.021
protein metabolic processGO:00195381830.021
cellular response to molecule of bacterial originGO:007121930.020
ion transmembrane transportGO:0034220910.020
negative regulation of cell communicationGO:0010648960.020
fin developmentGO:0033333770.020
protein localization to nucleusGO:003450430.020
programmed cell deathGO:00125011190.020
regulation of cellular amino acid metabolic processGO:000652100.020
response to hexoseGO:000974630.020
stem cell proliferationGO:007208940.020
leukocyte proliferationGO:007066110.020
response to organic substanceGO:00100331530.020
transmembrane transportGO:00550851200.020
response to drugGO:004249330.020
regulation of nucleotide catabolic processGO:003081120.020
bmp signaling pathwayGO:0030509520.020
negative regulation of signal transductionGO:0009968940.020
vasculature developmentGO:00019442780.020
organelle fusionGO:004828430.020
nuclear transportGO:005116940.019
macromolecule modificationGO:00434121110.019
ion transportGO:00068111140.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
small molecule metabolic processGO:0044281770.019
synaptic growth at neuromuscular junctionGO:005112420.019
response to radiationGO:0009314510.019
g1 s transition of mitotic cell cycleGO:000008210.019
negative regulation of mitosisGO:004583930.019
muscle structure developmentGO:00610611960.019
regulation of protein import into nucleusGO:004230620.019
regulation of biological qualityGO:00650082630.019
nucleocytoplasmic transportGO:000691340.019
protein homooligomerizationGO:005126030.019
regulation of protein transportGO:005122330.019
protein modification processGO:00362111000.019
negative regulation of developmental processGO:0051093650.019
positive regulation of cellular processGO:00485222010.019
neurotransmitter secretionGO:000726920.018
single organism membrane fusionGO:004480120.018
cell deathGO:00082191210.018
liver developmentGO:0001889960.018
inner ear developmentGO:00488391260.018
regulation of myotube differentiationGO:001083020.018
axis specificationGO:0009798430.018
positive regulation of cell adhesionGO:004578510.018
regulation of apoptotic processGO:0042981980.018
skeletal muscle tissue developmentGO:0007519670.018
ear developmentGO:00435831270.018
membrane fusionGO:006102520.018
regulation of cell developmentGO:00602841000.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
single fertilizationGO:000733830.017
regulation of synapse assemblyGO:005196330.017
regulation of multicellular organism growthGO:004001440.017
deathGO:00162651210.017
positive regulation of nucleoside metabolic processGO:004597910.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
regulation of multicellular organismal processGO:00512392770.017
growthGO:00400071740.017
apoptotic process involved in developmentGO:190274220.017
regulation of mrna processingGO:005068430.017
regulation of transmembrane transporter activityGO:002289820.017
negative regulation of metabolic processGO:0009892860.017
positive regulation of secretion by cellGO:190353210.017
regulation of cellular ketone metabolic processGO:001056570.017
endoderm developmentGO:0007492490.017
cell substrate adhesionGO:003158940.017
eye morphogenesisGO:00485921440.017
establishment of protein localization to organelleGO:007259440.017
regulation of circadian rhythmGO:004275240.017
regulation of stem cell proliferationGO:007209120.017
regulation of cellular carbohydrate metabolic processGO:001067540.016
regulation of tube sizeGO:003515020.016
epithelial cell differentiationGO:00308551160.016
muscle organ developmentGO:00075171010.016
mesenchyme developmentGO:00604851270.016
regulation of cell cycleGO:0051726520.016
atp catabolic processGO:000620040.016
centrosome cycleGO:000709810.016
regulation of protein catabolic processGO:004217610.016
lymphocyte proliferationGO:004665110.016
cellular response to oxygen levelsGO:007145310.016
cell projection morphogenesisGO:00488582440.016
regulation of programmed cell deathGO:00430671010.016
response to vitaminGO:003327330.016
nucleoside monophosphate catabolic processGO:000912540.016
cognitionGO:005089010.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
regulation of gtp catabolic processGO:003312420.016
regulation of epidermis developmentGO:004568220.016
regulation of ion transmembrane transporter activityGO:003241220.016
regulation of protein bindingGO:004339330.016
response to glucoseGO:000974930.016
multicellular organism growthGO:003526440.016
developmental growthGO:00485891660.016
embryonic skeletal system morphogenesisGO:0048704930.015
sensory organ morphogenesisGO:00905962000.015
regulation of protein ubiquitinationGO:003139630.015
negative regulation of protein kinase activityGO:000646940.015
phosphate containing compound metabolic processGO:00067961080.015
b cell activationGO:004211320.015
meiotic cell cycle processGO:190304630.015
regulation of autophagyGO:001050630.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
positive regulation of secretionGO:005104710.015
inositol lipid mediated signalingGO:004801720.015
negative regulation of kinase activityGO:003367340.015
regulation of response to nutrient levelsGO:003210710.015
cell cycleGO:0007049930.015
meiotic nuclear divisionGO:000712640.015
regulation of multicellular organismal developmentGO:20000262230.015
positive regulation of nucleotide catabolic processGO:003081310.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
mesoderm developmentGO:0007498880.015
regulation of cytoplasmic transportGO:190364940.015
positive regulation of immune effector processGO:000269930.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.014
phosphorus metabolic processGO:00067931090.014
golgi vesicle transportGO:004819330.014
endosomal transportGO:001619720.014
myeloid cell differentiationGO:0030099860.014
positive regulation of cellular amine metabolic processGO:003324000.014
establishment of protein localization to plasma membraneGO:009000210.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
mitotic cell cycle processGO:1903047480.014
positive regulation of gtpase activityGO:004354710.014
negative regulation of intracellular transportGO:003238730.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.014
protein localization to plasma membraneGO:007265910.014
protein targeting to nucleusGO:004474430.014
cellular response to hypoxiaGO:007145610.014
regulation of neural precursor cell proliferationGO:200017730.014
appendage developmentGO:0048736800.014
cilium assemblyGO:0042384580.014
nuclear importGO:005117030.014
protein polyubiquitinationGO:000020940.014
microtubule organizing center organizationGO:003102310.014
macromolecular complex assemblyGO:0065003350.014
epithelial cell developmentGO:0002064420.014
striated muscle tissue developmentGO:00147061100.014
response to glucocorticoidGO:005138410.014
regulation of skeletal muscle fiber developmentGO:004874220.014
cell fate specificationGO:0001708680.014
organic substance transportGO:0071702580.013
striated muscle cell differentiationGO:00511461290.013
proteasomal protein catabolic processGO:001049820.013
formation of primary germ layerGO:0001704620.013
protein importGO:001703830.013
regulation of synapse organizationGO:005080730.013
embryonic skeletal system developmentGO:0048706970.013
tissue regenerationGO:0042246740.013
regulation of epithelial cell proliferationGO:005067830.013
positive regulation of cellular metabolic processGO:0031325940.013
regulation of anatomical structure morphogenesisGO:00226031300.013
negative regulation of cell differentiationGO:0045596460.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
cell projection organizationGO:00300302840.013
regulation of cell shapeGO:000836010.013
rna localizationGO:000640340.013
regulation of bmp signaling pathwayGO:0030510390.013
secondary metabolic processGO:001974830.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.013
positive regulation of cytokine productionGO:000181920.013
regulation of intracellular protein transportGO:003315730.013
protein import into nucleusGO:000660630.013
mitotic cell cycle embryonicGO:004544820.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
odontogenesis of dentin containing toothGO:004247510.013
response to biotic stimulusGO:0009607970.013
i kappab kinase nf kappab signalingGO:000724940.013
synaptic vesicle localizationGO:009747910.013
peptidyl serine phosphorylationGO:001810510.013
embryonic cranial skeleton morphogenesisGO:0048701900.012
peptide metabolic processGO:000651810.012
cellular response to organic substanceGO:00713101050.012
positive regulation of cell communicationGO:0010647560.012
regulation of calcium ion transportGO:005192420.012
striated muscle cell developmentGO:00550021080.012
generation of neuronsGO:00486993850.012
regenerationGO:0031099910.012
determination of ventral identityGO:0048264210.012
retina development in camera type eyeGO:00600411460.012
regulation of gtpase activityGO:004308720.012
appendage morphogenesisGO:0035107560.012
peptide transportGO:001583310.012
compound eye developmentGO:004874920.012
glucose homeostasisGO:004259310.012
regulation of mitotic cell cycleGO:0007346250.012
skeletal muscle fiber developmentGO:0048741350.012
negative regulation of muscle cell differentiationGO:005114810.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of blood circulationGO:190352420.012
fertilizationGO:000956630.012
cellular component assembly involved in morphogenesisGO:00109271070.012
gastrulation with mouth forming secondGO:0001702440.012
response to woundingGO:00096111160.012
skeletal system morphogenesisGO:00487051020.012
regulation of protein targetingGO:190353320.012
dorsal convergenceGO:0060030140.012
positive regulation of striated muscle tissue developmentGO:004584410.012
neurotransmitter transportGO:000683620.012
regulation of protein complex assemblyGO:004325430.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
carbohydrate homeostasisGO:003350010.012
carbohydrate derivative metabolic processGO:1901135610.012
response to amino acidGO:004320020.012
interspecies interaction between organismsGO:004441940.012
macroautophagyGO:001623610.012
cellular response to decreased oxygen levelsGO:003629410.012
positive regulation of metabolic processGO:00098931080.012
neuron developmentGO:00486662620.012
regulation of translational initiationGO:000644610.012
cellular response to lipopolysaccharideGO:007122230.012
skeletal muscle organ developmentGO:0060538780.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
angiogenesisGO:00015251580.012
spindle assemblyGO:005122520.012
alcohol biosynthetic processGO:004616520.011
regulation of molecular functionGO:0065009700.011
regulation of meiotic cell cycleGO:005144510.011
multi organism processGO:00517041340.011
tube closureGO:006060610.011
single organism nuclear importGO:190259330.011
negative regulation of secretion by cellGO:190353120.011
regulation of transporter activityGO:003240920.011
cellular response to stressGO:0033554620.011
protein stabilizationGO:005082120.011
intracellular signal transductionGO:0035556850.011
negative regulation of multi organism processGO:004390130.011
positive regulation of map kinase activityGO:004340630.011
response to methylmercuryGO:0051597110.011
regulation of lipase activityGO:006019120.011
negative regulation of cytoplasmic transportGO:190365020.011
determination of dorsal ventral asymmetryGO:0048262340.011
peptidyl serine modificationGO:001820920.011
cell matrix adhesionGO:000716040.011
cardiac atrium developmentGO:000323040.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
convergent extension involved in gastrulationGO:0060027710.011
oocyte maturationGO:000155640.011
cellular carbohydrate metabolic processGO:004426240.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
proepicardium developmentGO:000334240.011
peptidyl lysine acetylationGO:001839420.011
olfactory lobe developmentGO:002198840.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
primary neural tube formationGO:001402010.011
actin filament based movementGO:003004810.011
negative regulation of myeloid cell differentiationGO:004563810.011
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.011
wound healingGO:0042060900.011
cellular response to biotic stimulusGO:007121630.011
astrocyte differentiationGO:004870810.011
taxisGO:00423301090.011
regulation of cellular protein metabolic processGO:0032268520.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
fin morphogenesisGO:0033334530.011
centrosome organizationGO:005129710.011
positive regulation of cellular component biogenesisGO:004408930.011
translational initiationGO:000641330.011
myotube cell developmentGO:0014904350.011
kupffer s vesicle developmentGO:0070121500.010
cellular component disassemblyGO:002241110.010
renal system developmentGO:0072001940.010
monovalent inorganic cation transportGO:0015672420.010
positive regulation of gtp catabolic processGO:003312610.010
hormone transportGO:000991420.010
cellular response to xenobiotic stimulusGO:0071466350.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
phagocytosis engulfmentGO:000691110.010
cartilage developmentGO:0051216960.010
regulation of cellular component organizationGO:0051128860.010
positive regulation of epithelial cell migrationGO:001063420.010
type b pancreatic cell developmentGO:000332340.010
positive regulation of response to stimulusGO:0048584800.010
erk1 and erk2 cascadeGO:007037140.010
cell part morphogenesisGO:00329902460.010
protein acylationGO:004354330.010
regulation of synaptic plasticityGO:004816710.010
negative regulation of gene expressionGO:0010629650.010
multi organism cellular processGO:004476420.010
hormone secretionGO:004687920.010
ribonucleoside monophosphate catabolic processGO:000915840.010

cx44.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.101
nervous system diseaseDOID:86300.033
eye diseaseDOID:561400.033
eye and adnexa diseaseDOID:149200.033
sensory system diseaseDOID:005015500.033
musculoskeletal system diseaseDOID:1700.020
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
cardiovascular system diseaseDOID:128700.015
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.015
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012