Danio rerio

0 known processes

mpz

myelin protein zero

(Aliases: p0,zgc:103775,wu:fc04b11,sc:d0186,MGC103775,MGC91987,wu:fi30g06)

mpz biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
head developmentGO:00603223030.904
generation of neuronsGO:00486993850.863
cognitionGO:005089010.785
brain developmentGO:00074202930.750
astrocyte differentiationGO:004870810.744
positive regulation of biological processGO:00485182530.699
central nervous system developmentGO:00074173870.595
dicarboxylic acid transportGO:000683510.561
organic substance biosynthetic processGO:19015762890.554
cellular component assemblyGO:00226071700.550
metencephalon developmentGO:0022037270.497
response to abiotic stimulusGO:00096281220.497
neuron projection regenerationGO:0031102160.465
regulation of gene expressionGO:00104682650.458
biosynthetic processGO:00090582940.440
amino acid transportGO:000686520.430
gene expressionGO:00104672520.425
neural nucleus developmentGO:0048857150.423
system processGO:00030081850.419
cellular biosynthetic processGO:00442492860.408
regulation of biological qualityGO:00650082630.392
signal transductionGO:00071654550.375
heterocycle biosynthetic processGO:00181302150.363
organic cyclic compound metabolic processGO:19013603010.362
heterocycle metabolic processGO:00464832900.362
organic cyclic compound biosynthetic processGO:19013622230.362
neuron developmentGO:00486662620.357
eye developmentGO:00016542770.356
aromatic compound biosynthetic processGO:00194382170.350
regulation of biosynthetic processGO:00098892500.332
regulation of nervous system developmentGO:0051960900.331
regulation of multicellular organismal developmentGO:20000262230.328
response to external stimulusGO:00096052640.319
regulation of developmental processGO:00507932470.315
regulation of macromolecule biosynthetic processGO:00105562250.287
cellular macromolecule biosynthetic processGO:00346452240.285
positive regulation of cellular processGO:00485222010.276
positive regulation of metabolic processGO:00098931080.269
cellular nitrogen compound metabolic processGO:00346412900.265
regulation of cell developmentGO:00602841000.262
neuron projection developmentGO:00311751800.262
cell projection organizationGO:00300302840.257
neuron projection morphogenesisGO:00488121610.247
developmental growthGO:00485891660.244
long chain fatty acid biosynthetic processGO:004275910.242
axon guidanceGO:0007411860.232
camera type eye developmentGO:00430102220.225
response to chemicalGO:00422213200.224
cell morphogenesisGO:00009022890.218
calcium ion homeostasisGO:0055074190.216
cellular nitrogen compound biosynthetic processGO:00442712180.214
organic acid metabolic processGO:0006082310.210
vesicle localizationGO:0051648270.210
synaptic vesicle transportGO:004848910.208
enzyme linked receptor protein signaling pathwayGO:00071671060.208
regulation of nucleobase containing compound metabolic processGO:00192192500.206
locomotionGO:00400113130.195
regulation of metabolic processGO:00192223590.194
small molecule metabolic processGO:0044281770.192
response to light stimulusGO:0009416460.190
glutamate receptor signaling pathwayGO:000721510.189
nucleic acid metabolic processGO:00903042440.189
cellular component maintenanceGO:004395430.185
Mouse
nerve developmentGO:0021675450.180
regulation of membrane potentialGO:0042391230.178
growthGO:00400071740.173
regulation of cellular component organizationGO:0051128860.168
synaptic vesicle localizationGO:009747910.164
cellular component movementGO:00069283350.161
nuclear migrationGO:000709730.160
peptidyl serine phosphorylationGO:001810510.154
lateral line developmentGO:0048882660.153
regenerationGO:0031099910.152
larval developmentGO:000216420.148
homeostatic processGO:00425921420.147
establishment of localizationGO:00512342440.143
pole plasm assemblyGO:000731540.142
axonal fasciculationGO:0007413110.140
oocyte anterior posterior axis specificationGO:000731440.138
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.135
synaptic vesicle recyclingGO:003646510.134
regulation of rna biosynthetic processGO:20011412130.132
cellular amino acid metabolic processGO:000652070.131
regulation of cardiac muscle cell contractionGO:008600410.129
response to amino acidGO:004320020.128
sensory system developmentGO:0048880760.124
cellular macromolecule metabolic processGO:00442603910.123
glial cell differentiationGO:0010001420.123
camera type eye morphogenesisGO:00485931080.120
cell cycleGO:0007049930.118
synaptic growth at neuromuscular junctionGO:005112420.118
carboxylic acid metabolic processGO:0019752220.117
neuron neuron synaptic transmissionGO:000727010.116
negative regulation of catabolic processGO:000989530.116
adult behaviorGO:003053420.115
single organism transportGO:00447652060.113
central nervous system myelinationGO:002201020.113
lateral line system developmentGO:0048925760.113
regulation of receptor activityGO:001046920.112
regulation of multicellular organismal processGO:00512392770.111
taxisGO:00423301090.111
peptidyl serine modificationGO:001820920.110
establishment of synaptic vesicle localizationGO:009748010.108
rna biosynthetic processGO:00327741810.107
hindbrain developmentGO:0030902910.106
neurological system processGO:0050877620.105
regulation of synaptic plasticityGO:004816710.105
regulation of transcription dna templatedGO:00063552130.104
nitrogen compound metabolic processGO:00068073190.102
regulation of cellular biosynthetic processGO:00313262450.102
purine ribonucleoside monophosphate catabolic processGO:000916940.100
locomotory behaviorGO:0007626340.099
developmental maturationGO:0021700340.099
wound healingGO:0042060900.097
midbrain developmentGO:0030901280.094
regulation of macromolecule metabolic processGO:00602553170.094
oligodendrocyte differentiationGO:0048709230.092
cellular response to stressGO:0033554620.092
positive regulation of cell adhesionGO:004578510.091
regionalizationGO:00030022740.091
nucleobase containing compound metabolic processGO:00061392740.091
macromolecule biosynthetic processGO:00090592270.090
cell surface receptor signaling pathwayGO:00071663250.090
neuron projection guidanceGO:0097485860.089
oxoacid metabolic processGO:0043436310.089
regulation of neuron differentiationGO:0045664560.088
regulation of nitrogen compound metabolic processGO:00511712510.088
circulatory system processGO:0003013870.088
agingGO:000756820.087
cellular response to chemical stimulusGO:00708871570.086
sensory perception of mechanical stimulusGO:0050954160.085
cellular ketone metabolic processGO:0042180110.084
neuron migrationGO:0001764220.083
positive regulation of transportGO:005105020.081
cell part morphogenesisGO:00329902460.078
regulation of cellular amino acid metabolic processGO:000652100.078
neurotransmitter transportGO:000683620.077
cellular response to decreased oxygen levelsGO:003629410.077
localization of cellGO:00516742440.077
neuron differentiationGO:00301823530.077
dorsal motor nucleus of vagus nerve developmentGO:002174440.077
neuromuscular process controlling balanceGO:005088530.076
regulation of muscle contractionGO:000693730.075
nucleic acid templated transcriptionGO:00976591810.074
purine nucleoside monophosphate catabolic processGO:000912840.074
reactive oxygen species biosynthetic processGO:190340910.074
cell morphogenesis involved in differentiationGO:00009041950.073
positive regulation of neurogenesisGO:0050769240.073
glial cell developmentGO:0021782200.070
nucleoside monophosphate catabolic processGO:000912540.070
transmission of nerve impulseGO:0019226190.069
single organism behaviorGO:0044708240.068
metal ion homeostasisGO:0055065260.068
somitogenesisGO:0001756870.067
protein localization to membraneGO:007265790.067
hormone secretionGO:004687920.065
transcription dna templatedGO:00063511810.065
organonitrogen compound metabolic processGO:1901564740.065
cellular aromatic compound metabolic processGO:00067252950.065
positive regulation of multicellular organismal processGO:0051240520.065
response to woundingGO:00096111160.065
dopaminergic neuron differentiationGO:0071542140.065
cellular component morphogenesisGO:00329893360.064
regulation of cell cycleGO:0051726520.063
cell migrationGO:00164772370.063
axonogenesisGO:00074091520.063
lens fiber cell developmentGO:007030730.062
opioid receptor signaling pathwayGO:003800330.061
behaviorGO:0007610740.061
regulation of cell matrix adhesionGO:000195210.060
regulation of localizationGO:00328791040.060
hormone transportGO:000991420.059
segmentationGO:0035282970.059
inner ear receptor stereocilium organizationGO:006012280.058
positive regulation of cell differentiationGO:0045597300.058
nucleobase containing compound biosynthetic processGO:00346542050.058
cell matrix adhesionGO:000716040.057
microtubule based processGO:0007017600.057
regulation of cell differentiationGO:00455951420.057
peripheral nervous system developmentGO:0007422550.056
cellular response to oxygen levelsGO:007145310.056
chemotaxisGO:00069351040.056
membrane organizationGO:0061024210.055
chemical homeostasisGO:0048878490.054
pons developmentGO:0021548110.054
negative regulation of cellular processGO:00485232830.054
response to stressGO:00069502630.054
single organism metabolic processGO:00447102170.054
establishment of vesicle localizationGO:0051650240.054
ion transmembrane transportGO:0034220910.054
epithelial tube morphogenesisGO:00605621480.054
somite developmentGO:0061053960.053
polarized epithelial cell differentiationGO:003085940.053
response to drugGO:004249330.053
positive regulation of cellular amino acid metabolic processGO:004576400.053
cellular component biogenesisGO:00440851780.052
regulation of nucleic acid templated transcriptionGO:19035062130.052
negative regulation of metabolic processGO:0009892860.051
positive regulation of wound healingGO:009030310.051
negative regulation of epithelial cell migrationGO:001063310.051
alpha amino acid metabolic processGO:190160530.051
positive regulation of catalytic activityGO:0043085250.051
peptide transportGO:001583310.050
neural tube developmentGO:0021915620.050
macromolecular complex assemblyGO:0065003350.050
response to radiationGO:0009314510.050
cell substrate adhesionGO:003158940.050
positive regulation of nitrogen compound metabolic processGO:0051173690.049
regulation of oligodendrocyte differentiationGO:004871310.049
regulation of cellular macromolecule biosynthetic processGO:20001122220.049
regulation of hormone secretionGO:004688320.048
regulation of cell projection assemblyGO:006049140.048
positive regulation of cellular biosynthetic processGO:0031328680.048
regulation of transcription from rna polymerase ii promoterGO:00063571140.047
positive regulation of nervous system developmentGO:0051962250.047
cellular response to nutrient levelsGO:003166920.046
axon regenerationGO:0031103140.046
blood circulationGO:0008015870.046
positive regulation of biosynthetic processGO:0009891680.045
regulation of postsynaptic membrane potentialGO:006007810.045
cellular response to organic substanceGO:00713101050.045
maternal determination of anterior posterior axis embryoGO:000835840.045
meiotic nuclear divisionGO:000712640.044
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.044
cellular amine metabolic processGO:004410620.043
regulation of cellular amine metabolic processGO:003323800.043
cytoplasm organizationGO:000702840.043
regulation of phospholipase activityGO:001051720.042
positive regulation of gliogenesisGO:001401520.042
phosphorus metabolic processGO:00067931090.042
neuron recognitionGO:0008038180.041
peripheral nervous system neuron developmentGO:0048935220.041
purine containing compound metabolic processGO:0072521290.041
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.041
mesenchymal cell differentiationGO:0048762870.040
actin filament based movementGO:003004810.040
nitrogen compound transportGO:0071705230.039
organonitrogen compound biosynthetic processGO:1901566470.039
heart contractionGO:0060047710.039
erk1 and erk2 cascadeGO:007037140.038
medulla oblongata developmentGO:002155040.038
regulation of nucleoside metabolic processGO:000911820.038
positive regulation of developmental processGO:0051094500.038
amine metabolic processGO:000930820.038
action potentialGO:0001508190.037
regulation of protein complex assemblyGO:004325430.037
heart developmentGO:00075073130.037
metal ion transportGO:0030001580.037
cell junction maintenanceGO:003433120.037
Mouse
ribonucleoside monophosphate catabolic processGO:000915840.037
axon ensheathment in central nervous systemGO:003229120.037
retina development in camera type eyeGO:00600411460.036
rna metabolic processGO:00160702190.036
long chain fatty acid metabolic processGO:000167610.036
stem cell differentiationGO:00488631170.036
cell projection morphogenesisGO:00488582440.036
single organism membrane organizationGO:0044802200.035
positive regulation of catabolic processGO:000989640.035
cellular component assembly involved in morphogenesisGO:00109271070.035
vasculature developmentGO:00019442780.034
defense responseGO:0006952470.034
regulation of neurogenesisGO:0050767870.034
positive regulation of cellular component biogenesisGO:004408930.033
negative regulation of gene expressionGO:0010629650.033
regulation of inner ear receptor cell differentiationGO:200098010.033
macromolecule modificationGO:00434121110.032
positive regulation of nucleic acid templated transcriptionGO:1903508570.032
regulation of rna metabolic processGO:00512522240.032
positive regulation of nucleobase containing compound metabolic processGO:0045935690.032
negative regulation of secretionGO:005104820.032
axon extensionGO:0048675450.031
transportGO:00068102200.031
response to zinc ionGO:001004360.031
epithelial tube formationGO:0072175190.031
inflammatory responseGO:000695480.031
modification dependent macromolecule catabolic processGO:004363230.031
sensory perceptionGO:0007600390.031
positive regulation of gene expressionGO:0010628710.030
regulation of filopodium assemblyGO:005148920.030
modification dependent protein catabolic processGO:001994130.030
tissue regenerationGO:0042246740.030
rna localizationGO:000640340.030
transmembrane transportGO:00550851200.030
cell motilityGO:00488702440.030
single organism localizationGO:19025782250.030
regulation of response to nutrient levelsGO:003210710.030
response to superoxideGO:000030320.030
tube formationGO:0035148250.030
regulation of cellular ketone metabolic processGO:001056570.029
maintenance of locationGO:005123540.029
neuromuscular processGO:005090570.029
positive regulation of macromolecule metabolic processGO:0010604930.029
locomotor rhythmGO:004547530.029
cellular homeostasisGO:0019725260.029
stem cell fate commitmentGO:004886510.029
guanosine containing compound metabolic processGO:190106840.029
vestibular reflexGO:006000520.029
positive regulation of cellular amine metabolic processGO:003324000.029
mesodermal cell migrationGO:0008078120.028
blood vessel morphogenesisGO:00485142160.028
regulation of blood vessel sizeGO:005088020.028
epithelial cell differentiationGO:00308551160.028
inner ear receptor cell fate commitmentGO:006012040.028
phenol containing compound biosynthetic processGO:004618940.028
cell morphogenesis involved in neuron differentiationGO:00486671630.028
determination of intestine left right asymmetryGO:007190820.028
positive regulation of cellular metabolic processGO:0031325940.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.027
cellular response to external stimulusGO:007149620.027
anterior posterior pattern specificationGO:00099521520.027
reflexGO:006000420.027
regulation of primary metabolic processGO:00800903110.027
organophosphate metabolic processGO:0019637370.027
membrane hyperpolarizationGO:006008110.027
muscle cell developmentGO:00550011150.027
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
skeletal system developmentGO:00015011810.026
spermatid developmentGO:000728620.026
cell proliferationGO:0008283800.026
cellular response to hypoxiaGO:007145610.026
synaptic transmissionGO:0007268350.026
embryo development ending in birth or egg hatchingGO:00097922710.026
ion transportGO:00068111140.026
cell maturationGO:0048469230.026
regulation of transmembrane transporter activityGO:002289820.026
regulation of catalytic activityGO:0050790550.025
deathGO:00162651210.025
positive regulation of cellular catabolic processGO:003133130.025
regulation of neuron projection developmentGO:0010975400.025
response to glucocorticoidGO:005138410.025
positive regulation of erk1 and erk2 cascadeGO:007037420.025
carbohydrate derivative metabolic processGO:1901135610.025
chordate embryonic developmentGO:00430092710.025
neurotransmitter secretionGO:000726920.025
positive regulation of purine nucleotide biosynthetic processGO:190037380.024
positive regulation of phosphate metabolic processGO:0045937210.024
reactive nitrogen species metabolic processGO:200105700.024
ion homeostasisGO:0050801410.024
positive regulation of cytokine productionGO:000181920.024
auditory receptor cell differentiationGO:0042491150.024
fatty acid biosynthetic processGO:000663340.024
catabolic processGO:0009056320.024
morphogenesis of an epitheliumGO:00020093330.024
gliogenesisGO:0042063450.023
multicellular organism growthGO:003526440.023
gtp metabolic processGO:004603940.023
regulation of ion transportGO:0043269220.023
positive regulation of protein complex assemblyGO:003133420.023
regulation of cell deathGO:00109411030.023
regulation of protein kinase b signalingGO:005189680.023
regulation of system processGO:0044057400.023
regulation of transmembrane transportGO:0034762180.023
regulation of axonogenesisGO:0050770320.023
intracellular receptor signaling pathwayGO:0030522300.023
cell cell junction maintenanceGO:004521710.023
Mouse
cellular response to toxic substanceGO:009723710.023
regulation of purine nucleotide metabolic processGO:1900542170.023
eye morphogenesisGO:00485921440.022
l amino acid transportGO:001580710.022
cerebellar granular layer developmentGO:002168130.022
regulation of cellular metabolic processGO:00313233200.022
mesenchymal cell developmentGO:0014031780.022
small molecule biosynthetic processGO:0044283160.022
atp catabolic processGO:000620040.022
regulation of response to stimulusGO:00485832690.022
regulation of neurotransmitter transportGO:005158810.022
apoptotic processGO:00069151160.022
single organism organelle organizationGO:19025891990.022
single organism reproductive processGO:0044702400.022
phosphatidylinositol mediated signalingGO:004801520.022
small molecule catabolic processGO:004428230.021
catecholamine biosynthetic processGO:004242320.021
regulation of cytokine productionGO:000181730.021
dicarboxylic acid metabolic processGO:004364810.021
cation homeostasisGO:0055080330.021
positive regulation of glial cell proliferationGO:006025210.021
ribonucleoprotein complex biogenesisGO:0022613130.021
phosphorylationGO:0016310690.021
morphogenesis of embryonic epitheliumGO:0016331300.021
regulation of cell communicationGO:00106462320.021
angiogenesisGO:00015251580.021
oogenesisGO:0048477140.021
small gtpase mediated signal transductionGO:000726480.021
steroid hormone secretionGO:003592910.021
regulation of steroid hormone secretionGO:200083110.020
gtp catabolic processGO:000618420.020
forebrain developmentGO:0030900960.020
positive regulation of signalingGO:0023056560.020
androgen metabolic processGO:000820920.020
auditory receptor cell morphogenesisGO:000209340.020
negative regulation of programmed cell deathGO:0043069580.020
positive regulation of lyase activityGO:005134960.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of multicellular organism growthGO:004001440.020
blood vessel developmentGO:00015682460.020
negative regulation of macromolecule metabolic processGO:0010605760.019
cellular protein modification processGO:00064641000.019
negative regulation of response to stimulusGO:00485851040.019
positive regulation of cell developmentGO:0010720250.019
establishment of epithelial cell polarityGO:009016220.019
oligodendrocyte developmentGO:001400370.019
neuroblast proliferationGO:000740520.019
extracellular matrix assemblyGO:008502910.019
regulation of signalingGO:00230512350.019
muscle organ developmentGO:00075171010.019
developmental cell growthGO:0048588520.019
sensory perception of painGO:001923310.019
positive regulation of cell matrix adhesionGO:000195410.019
sensory perception of touchGO:005097520.019
regulation of erk1 and erk2 cascadeGO:007037240.019
proteasomal protein catabolic processGO:001049820.019
response to oxygen containing compoundGO:1901700550.019
purine ribonucleotide metabolic processGO:0009150270.019
intracellular signal transductionGO:0035556850.018
branching morphogenesis of a nerveGO:004875540.018
response to inorganic substanceGO:0010035380.018
positive regulation of phosphorus metabolic processGO:0010562210.018
myelinationGO:0042552180.018
startle responseGO:000196440.018
neuromast developmentGO:0048884460.018
positive regulation of cell cycleGO:004578730.018
regulation of reactive oxygen species metabolic processGO:200037720.018
protein complex biogenesisGO:0070271300.018
gastrulationGO:00073692080.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
establishment of localization in cellGO:0051649770.018
reactive oxygen species metabolic processGO:007259360.018
olfactory lobe developmentGO:002198840.018
equilibrioceptionGO:005095720.018
regulation of gtp catabolic processGO:003312420.018
negative regulation of cellular metabolic processGO:0031324770.018
cell cell signalingGO:0007267520.018
single organism membrane fusionGO:004480120.018
inositol lipid mediated signalingGO:004801720.018
cellular process involved in reproduction in multicellular organismGO:0022412280.017
purine nucleotide metabolic processGO:0006163270.017
motor neuron axon guidanceGO:0008045230.017
cardiocyte differentiationGO:0035051440.017
regulation of dendrite developmentGO:005077330.017
glial cell proliferationGO:001400940.017
cellular protein metabolic processGO:00442671290.017
regulation of cell shapeGO:000836010.017
cell deathGO:00082191210.017
regulation of cellular component movementGO:0051270550.017
stem cell proliferationGO:007208940.017
negative regulation of cell deathGO:0060548600.017
regulation of ion transmembrane transporter activityGO:003241220.017
digestive tract developmentGO:00485652650.017
regulation of wound healingGO:006104120.017
multicellular organismal signalingGO:0035637220.017
negative regulation of signalingGO:0023057960.017
lipid catabolic processGO:001604240.016
auditory receptor cell fate specificationGO:004266720.016
ubiquitin dependent protein catabolic processGO:000651130.016
cellular localizationGO:0051641970.016
negative regulation of protein phosphorylationGO:000193340.016
cellular amino acid biosynthetic processGO:000865220.016
inorganic cation transmembrane transportGO:0098662500.016
cellular response to extracellular stimulusGO:003166820.016
response to organic substanceGO:00100331530.016
protein complex assemblyGO:0006461300.016
negative regulation of hormone secretionGO:004688820.016
cell fate commitmentGO:0045165990.016
negative regulation of multicellular organismal processGO:0051241690.016
carbohydrate derivative biosynthetic processGO:1901137430.016
response to monosaccharideGO:003428430.016
negative regulation of macromolecule biosynthetic processGO:0010558480.016
rna 3 end processingGO:003112320.016
regulation of anatomical structure morphogenesisGO:00226031300.016
cell adhesionGO:0007155400.016
neuroblast differentiationGO:001401610.016
negative regulation of nitrogen compound metabolic processGO:0051172590.016
heart processGO:0003015710.016
cellular lipid metabolic processGO:0044255360.015
negative regulation of heart contractionGO:004582220.015
positive regulation of purine nucleotide metabolic processGO:190054490.015
anterior lateral line nerve developmentGO:004890940.015
cellular response to starvationGO:000926710.015
monocarboxylic acid metabolic processGO:0032787170.015
regulation of cellular protein metabolic processGO:0032268520.015
programmed cell deathGO:00125011190.015
synaptic vesicle endocytosisGO:004848810.015
single organism biosynthetic processGO:0044711710.015
nucleobase containing small molecule metabolic processGO:0055086320.015
response to growth factorGO:0070848390.015
nucleocytoplasmic transportGO:000691340.015
regulation of programmed cell deathGO:00430671010.015
acylglycerol homeostasisGO:005509020.015
retina morphogenesis in camera type eyeGO:0060042790.015

mpz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
leukodystrophyDOID:1057900.744
disease of anatomical entityDOID:700.744
brain diseaseDOID:93600.744
central nervous system diseaseDOID:33100.744
cerebral degenerationDOID:144300.744
nervous system diseaseDOID:86300.744
cardiovascular system diseaseDOID:128700.101
paraplegiaDOID:60700.039
hereditary spastic paraplegiaDOID:247600.039
musculoskeletal system diseaseDOID:1700.025