Danio rerio

14 known processes

f2

coagulation factor II (thrombin)

(Aliases: wu:fd42e09,wu:fd59d01,wu:fb57c10,zgc:66319)

f2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to stressGO:00069502630.090
positive regulation of transportGO:005105020.076
Human
regulation of establishment of protein localizationGO:007020140.067
larval developmentGO:000216420.066
localization of cellGO:00516742440.064
regulation of protein transportGO:005122330.059
regulation of biological qualityGO:00650082630.053
gene expressionGO:00104672520.051
Human Mouse
cell migrationGO:00164772370.051
cellular component movementGO:00069283350.050
nuclear transportGO:005116940.048
cellular response to lipopolysaccharideGO:007122230.047
signal transductionGO:00071654550.045
Human Mouse
regulation of cellular metabolic processGO:00313233200.044
Human
morphogenesis of an epitheliumGO:00020093330.043
protein importGO:001703830.043
establishment of protein localization to organelleGO:007259440.042
positive regulation of secretion by cellGO:190353210.042
nucleocytoplasmic transportGO:000691340.041
cell motilityGO:00488702440.041
guanosine containing compound catabolic processGO:190106920.040
system processGO:00030081850.040
agingGO:000756820.038
positive regulation of biological processGO:00485182530.037
Human Mouse
digestive tract developmentGO:00485652650.037
regulation of cytokine productionGO:000181730.037
hepaticobiliary system developmentGO:0061008980.037
regulation of extrinsic apoptotic signaling pathwayGO:200123630.036
tissue remodelingGO:004877140.036
immune system processGO:00023762410.035
gtp catabolic processGO:000618420.035
maintenance of locationGO:005123540.035
cellular nitrogen compound metabolic processGO:00346412900.035
extrinsic apoptotic signaling pathwayGO:009719130.035
cellular response to molecule of bacterial originGO:007121930.035
positive regulation of cytokine productionGO:000181920.034
response to chemicalGO:00422213200.034
mitochondrion organizationGO:000700540.034
regulation of cell substrate adhesionGO:001081010.034
regulation of nitrogen compound metabolic processGO:00511712510.033
proteasomal protein catabolic processGO:001049820.033
blood circulationGO:0008015870.033
tube morphogenesisGO:00352393490.033
cellular response to estrogen stimulusGO:0071391240.033
protein secretionGO:000930610.033
negative regulation of cellular processGO:00485232830.033
Human
positive regulation of catabolic processGO:000989640.032
protein import into nucleusGO:000660630.032
positive regulation of cell cycleGO:004578730.032
regulation of macromolecule metabolic processGO:00602553170.031
Human Mouse
cellular protein catabolic processGO:004425740.031
regulation of primary metabolic processGO:00800903110.031
Human
positive regulation of cellular processGO:00485222010.031
Human Mouse
response to woundingGO:00096111160.031
regulation of gene expressionGO:00104682650.030
Human Mouse
locomotionGO:00400113130.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
negative regulation of biological processGO:00485193040.030
Human
organic cyclic compound metabolic processGO:19013603010.029
regulation of multicellular organismal processGO:00512392770.029
Human
single organism nuclear importGO:190259330.029
heart contractionGO:0060047710.029
positive regulation of cellular component biogenesisGO:004408930.028
regulation of cytoplasmic transportGO:190364940.028
Human
meiotic nuclear divisionGO:000712640.028
lipid storageGO:001991510.028
gtp metabolic processGO:004603940.028
protein localization to nucleusGO:003450430.028
embryonic organ developmentGO:00485683810.028
cellular amino acid metabolic processGO:000652070.027
digestive system developmentGO:00551232890.027
nuclear importGO:005117030.027
homeostatic processGO:00425921420.027
Human
rna biosynthetic processGO:00327741810.027
liver developmentGO:0001889960.027
cell substrate adhesionGO:003158940.026
regulation of nucleocytoplasmic transportGO:004682220.026
negative regulation of protein phosphorylationGO:000193340.025
synaptic transmission cholinergicGO:000727140.025
neurotransmitter transportGO:000683620.025
guanosine containing compound metabolic processGO:190106840.025
positive regulation of cellular catabolic processGO:003133130.025
organic cyclic compound biosynthetic processGO:19013622230.025
exocytosisGO:000688710.025
regulation of hormone secretionGO:004688320.025
heterocycle metabolic processGO:00464832900.025
regulation of intracellular protein transportGO:003315730.025
cellular response to extracellular stimulusGO:003166820.025
phagocytosisGO:000690930.024
nucleobase containing compound metabolic processGO:00061392740.024
embryonic organ morphogenesisGO:00485622740.024
response to external stimulusGO:00096052640.024
Human Rat
regulation of cellular amino acid metabolic processGO:000652100.024
negative regulation of response to stimulusGO:00485851040.024
Human
positive regulation of cytosolic calcium ion concentrationGO:000720440.024
Human
cellular response to nutrient levelsGO:003166920.024
response to organic substanceGO:00100331530.024
angiogenesisGO:00015251580.024
cognitionGO:005089010.024
regulation of signal transductionGO:00099662250.024
Human Mouse
regulation of response to stimulusGO:00485832690.023
Human Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.023
cell surface receptor signaling pathwayGO:00071663250.023
Human
cellular aromatic compound metabolic processGO:00067252950.023
regulation of protein localization to nucleusGO:190018020.023
regulation of metabolic processGO:00192223590.023
Human Mouse
peptide transportGO:001583310.023
regulation of protein import into nucleusGO:004230620.023
regulation of protein catabolic processGO:004217610.023
regulation of meiotic cell cycleGO:005144510.023
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.022
blood vessel developmentGO:00015682460.022
regulation of multicellular organismal developmentGO:20000262230.022
Human
cellular response to biotic stimulusGO:007121630.022
regulation of inflammatory responseGO:005072720.022
heterocycle biosynthetic processGO:00181302150.022
regulation of cellular amine metabolic processGO:003323800.021
regulation of protein targetingGO:190353320.021
positive regulation of secretionGO:005104710.021
regulation of developmental processGO:00507932470.021
Human Mouse
ubiquitin dependent protein catabolic processGO:000651130.021
circulatory system processGO:0003013870.021
rna localizationGO:000640340.021
sequestering of metal ionGO:005123830.021
rna metabolic processGO:00160702190.020
regulation of epithelial cell proliferationGO:005067830.020
negative regulation of protein transportGO:005122430.020
biosynthetic processGO:00090582940.020
Human
triglyceride homeostasisGO:007032820.020
amine metabolic processGO:000930820.020
cellular response to organic substanceGO:00713101050.020
regulation of protein complex assemblyGO:004325430.020
single organism transportGO:00447652060.020
Human
phosphate containing compound metabolic processGO:00067961080.020
Human
secondary metabolic processGO:001974830.020
regulation of nucleoside metabolic processGO:000911820.020
gastrulationGO:00073692080.020
nucleobase containing compound biosynthetic processGO:00346542050.020
macromolecule biosynthetic processGO:00090592270.020
Human
negative regulation of protein kinase activityGO:000646940.020
cellular response to external stimulusGO:007149620.019
Rat
positive regulation of metabolic processGO:00098931080.019
Human
organonitrogen compound metabolic processGO:1901564740.019
nucleic acid templated transcriptionGO:00976591810.019
modification dependent macromolecule catabolic processGO:004363230.019
heart morphogenesisGO:00030071560.019
regulation of multicellular organism growthGO:004001440.019
neurotransmitter secretionGO:000726920.019
regulation of neural precursor cell proliferationGO:200017730.019
determination of bilateral symmetryGO:00098552040.019
transportGO:00068102200.019
Human
modification dependent protein catabolic processGO:001994130.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
multicellular organism growthGO:003526440.018
female sex differentiationGO:004666040.018
negative regulation of catabolic processGO:000989530.018
synaptic growth at neuromuscular junctionGO:005112420.018
organic substance biosynthetic processGO:19015762890.018
Human
adult behaviorGO:003053420.018
regulation of tube sizeGO:003515020.018
cellular amine metabolic processGO:004410620.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of cell differentiationGO:00455951420.018
Human
sensory organ developmentGO:00074233930.018
retina development in camera type eyeGO:00600411460.017
negative regulation of signal transductionGO:0009968940.017
regulation of blood vessel sizeGO:005088020.017
establishment of localizationGO:00512342440.017
Human
female gonad developmentGO:000858540.017
cell matrix adhesionGO:000716040.017
heart loopingGO:0001947940.017
heart developmentGO:00075073130.017
central nervous system developmentGO:00074173870.017
Human
positive regulation of blood circulationGO:190352420.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
single organism metabolic processGO:00447102170.017
Human
single organism localizationGO:19025782250.017
Human
camera type eye developmentGO:00430102220.017
proteolysisGO:0006508380.017
Human Mouse Rat
mitochondrial transportGO:000683920.017
regulation of cell activationGO:005086510.017
regulation of macromolecule biosynthetic processGO:00105562250.017
Human
embryonic skeletal system developmentGO:0048706970.016
growthGO:00400071740.016
Mouse
hormone secretionGO:004687920.016
leukocyte proliferationGO:007066110.016
negative regulation of cellular catabolic processGO:003133030.016
transcription dna templatedGO:00063511810.016
embryonic heart tube morphogenesisGO:00031431080.016
cellular response to starvationGO:000926710.016
regulation of synapse organizationGO:005080730.016
ear developmentGO:00435831270.016
epithelial cell differentiationGO:00308551160.016
regulation of purine nucleotide catabolic processGO:003312120.016
b cell activationGO:004211320.016
myeloid cell differentiationGO:0030099860.016
cellular ketone metabolic processGO:0042180110.016
regulation of rna biosynthetic processGO:20011412130.016
neuron differentiationGO:00301823530.016
protein metabolic processGO:00195381830.016
Human Mouse Rat
response to nutrientGO:000758430.016
response to uvGO:000941130.016
negative regulation of cytoplasmic transportGO:190365020.015
cytokinesisGO:000091030.015
regulation of biosynthetic processGO:00098892500.015
Human
response to topologically incorrect proteinGO:003596620.015
aromatic compound biosynthetic processGO:00194382170.015
eye developmentGO:00016542770.015
regulation of nervous system developmentGO:0051960900.015
Human
negative regulation of gene expressionGO:0010629650.015
Human
germ cell migrationGO:000835480.015
digestive tract morphogenesisGO:00485462310.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
cell cycle arrestGO:000705010.015
negative regulation of kinase activityGO:003367340.015
regulation of cell deathGO:00109411030.015
immune system developmentGO:00025201910.015
cellular response to chemical stimulusGO:00708871570.015
hormone transportGO:000991420.015
gland developmentGO:00487321430.015
g1 s transition of mitotic cell cycleGO:000008210.015
vasculature developmentGO:00019442780.014
vasculogenesisGO:0001570410.014
nucleic acid metabolic processGO:00903042440.014
cellular response to lipidGO:0071396390.014
cellular component assemblyGO:00226071700.014
regulation of gtpase activityGO:004308720.014
protein targeting to nucleusGO:004474430.014
programmed cell deathGO:00125011190.014
nitrogen compound metabolic processGO:00068073190.014
skeletal system developmentGO:00015011810.014
phosphorus metabolic processGO:00067931090.014
Human
positive regulation of dna metabolic processGO:005105410.014
convergent extensionGO:00600261180.014
antimicrobial humoral responseGO:001973020.014
development of primary female sexual characteristicsGO:004654540.014
stem cell divisionGO:001714510.014
endocrine processGO:005088620.014
head developmentGO:00603223030.014
positive regulation of purine nucleotide catabolic processGO:003312310.013
positive regulation of macromolecule metabolic processGO:0010604930.013
Human
protein polymerizationGO:005125840.013
ameboidal type cell migrationGO:00016671430.013
regulation of transcription dna templatedGO:00063552130.013
regulation of programmed cell deathGO:00430671010.013
epithelial tube morphogenesisGO:00605621480.013
lymphocyte proliferationGO:004665110.013
response to amino acidGO:004320020.013
glucose homeostasisGO:004259310.013
negative regulation of defense responseGO:003134820.013
blood vessel morphogenesisGO:00485142160.013
positive regulation of cellular amine metabolic processGO:003324000.013
sensory organ morphogenesisGO:00905962000.013
intracellular mrna localizationGO:000829810.013
organelle organizationGO:00069962270.013
positive regulation of cell adhesionGO:004578510.013
regulation of synapse assemblyGO:005196330.013
negative regulation of metabolic processGO:0009892860.013
Human
regulation of protein polymerizationGO:003227120.012
regulation of reactive oxygen species metabolic processGO:200037720.012
Human
regulation of cellular ketone metabolic processGO:001056570.012
positive regulation of cytoskeleton organizationGO:005149530.012
er nucleus signaling pathwayGO:000698420.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
regulation of protein metabolic processGO:0051246560.012
Human
positive regulation of cell activationGO:005086710.012
regulation of gtp catabolic processGO:003312420.012
regulation of organ growthGO:004662030.012
nephron epithelium morphogenesisGO:007208810.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
developmental growthGO:00485891660.012
regulation of cell projection assemblyGO:006049140.012
neuron projection developmentGO:00311751800.012
i kappab kinase nf kappab signalingGO:000724940.012
cellular component disassemblyGO:002241110.012
epidermis developmentGO:0008544480.012
cellular component biogenesisGO:00440851780.012
specification of symmetryGO:00097992040.012
mitotic dna integrity checkpointGO:004477440.012
negative regulation of protein maturationGO:1903318100.012
Human
response to monosaccharideGO:003428430.012
embryonic heart tube developmentGO:00350501330.012
positive regulation of cell divisionGO:005178120.012
regenerationGO:0031099910.012
regulation of bindingGO:005109830.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
regulation of calcium ion transportGO:005192420.012
Human
wound healingGO:0042060900.012
cellular response to organic cyclic compoundGO:0071407380.012
positive regulation of protein complex assemblyGO:003133420.011
carbohydrate biosynthetic processGO:001605110.011
mitotic dna damage checkpointGO:004477340.011
sensory perception of chemical stimulusGO:000760630.011
determination of heart left right asymmetryGO:00613711170.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
response to unfolded proteinGO:000698620.011
regulation of bone remodelingGO:004685020.011
positive regulation of immune effector processGO:000269930.011
neuron developmentGO:00486662620.011
deathGO:00162651210.011
apoptotic processGO:00069151160.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of reproductive processGO:200024140.011
cellular response to hypoxiaGO:007145610.011
neuroblast proliferationGO:000740520.011
ovulation cycle processGO:002260220.011
response to hydrogen peroxideGO:004254230.011
transcription from rna polymerase ii promoterGO:0006366800.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
developmental pigmentationGO:0048066480.011
regulation of cellular component organizationGO:0051128860.011
Mouse
stem cell proliferationGO:007208940.011
response to glucoseGO:000974930.011
cellular response to steroid hormone stimulusGO:0071383310.011
ion homeostasisGO:0050801410.011
Human
post embryonic morphogenesisGO:000988640.011
negative regulation of proteolysisGO:0045861100.011
Human
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
spermatid differentiationGO:004851520.011
astrocyte differentiationGO:004870810.011
Human
organelle assemblyGO:00709251100.011
positive regulation of chromatin modificationGO:190331010.011
zymogen activationGO:003163830.011
mononuclear cell proliferationGO:003294310.011
regulation of cell communicationGO:00106462320.011
Human Mouse
response to carbohydrateGO:000974330.011
negative regulation of cell deathGO:0060548600.011
peptidyl serine modificationGO:001820920.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
negative regulation of intracellular transportGO:003238730.010
endoplasmic reticulum unfolded protein responseGO:003096820.010
regulation of dendrite developmentGO:005077330.010
dna catabolic processGO:000630810.010
cellular response to reactive oxygen speciesGO:003461420.010
organic acid metabolic processGO:0006082310.010
regulation of localizationGO:00328791040.010
Human
membrane invaginationGO:001032410.010
cell part morphogenesisGO:00329902460.010
inner ear developmentGO:00488391260.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
regulation of nucleotide catabolic processGO:003081120.010
autophagyGO:000691440.010
regulation of exocytosisGO:001715710.010
positive regulation of nucleoside metabolic processGO:004597910.010
peptidyl serine phosphorylationGO:001810510.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
negative regulation of epithelial cell proliferationGO:005068010.010
cellular response to oxygen levelsGO:007145310.010
multicellular organismal response to stressGO:003355520.010
otic vesicle developmentGO:0071599420.010
negative regulation of chromosome organizationGO:200125110.010
negative regulation of mapk cascadeGO:004340940.010
regulation of cellular biosynthetic processGO:00313262450.010

f2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
Human
immune system diseaseDOID:291400.021
Human
hematopoietic system diseaseDOID:7400.019
Human
disease of metabolismDOID:001466700.016
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
nervous system diseaseDOID:86300.011