Danio rerio

0 known processes

fh

fumarate hydratase

(Aliases: zf-e152,zgc:77498,zgc:66253,ns:zf-e152,Fh1,MGC66253)

fh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.078
larval developmentGO:000216420.074
regulation of multicellular organism growthGO:004001440.065
locomotionGO:00400113130.063
agingGO:000756820.063
nuclear transportGO:005116940.062
digestive system developmentGO:00551232890.061
cellular carbohydrate metabolic processGO:004426240.054
vasculature developmentGO:00019442780.050
nucleocytoplasmic transportGO:000691340.049
regulation of multicellular organismal processGO:00512392770.046
cellular aromatic compound metabolic processGO:00067252950.044
localization of cellGO:00516742440.043
digestive tract developmentGO:00485652650.043
multicellular organism growthGO:003526440.042
system processGO:00030081850.042
alpha amino acid metabolic processGO:190160530.042
regulation of macromolecule metabolic processGO:00602553170.042
signal transductionGO:00071654550.041
immune system developmentGO:00025201910.041
response to drugGO:004249330.040
negative regulation of neural precursor cell proliferationGO:200017810.040
biosynthetic processGO:00090582940.039
regulation of cellular metabolic processGO:00313233200.039
cell substrate adhesionGO:003158940.039
cognitionGO:005089010.039
maintenance of locationGO:005123540.038
gastrulationGO:00073692080.038
protein localization to nucleusGO:003450430.037
phagocytosisGO:000690930.037
stem cell proliferationGO:007208940.036
regulation of biological qualityGO:00650082630.035
negative regulation of biological processGO:00485193040.035
nitrogen compound metabolic processGO:00068073190.035
regulation of establishment of protein localizationGO:007020140.034
negative regulation of cellular processGO:00485232830.034
cellular nitrogen compound metabolic processGO:00346412900.033
tube morphogenesisGO:00352393490.032
brain developmentGO:00074202930.032
cellular macromolecule metabolic processGO:00442603910.032
cell surface receptor signaling pathwayGO:00071663250.032
heterocycle metabolic processGO:00464832900.031
regulation of developmental processGO:00507932470.031
regulation of nitrogen compound metabolic processGO:00511712510.031
cellular nitrogen compound biosynthetic processGO:00442712180.030
stem cell maintenanceGO:001982740.030
establishment of protein localization to organelleGO:007259440.030
organic cyclic compound metabolic processGO:19013603010.030
lymphocyte proliferationGO:004665110.030
positive regulation of transportGO:005105020.029
cell morphogenesisGO:00009022890.029
blood vessel developmentGO:00015682460.029
amine metabolic processGO:000930820.029
regulation of neural precursor cell proliferationGO:200017730.029
cellular component movementGO:00069283350.028
cellular macromolecule biosynthetic processGO:00346452240.028
regulation of protein transportGO:005122330.028
protein import into nucleusGO:000660630.028
regulation of cytokine productionGO:000181730.028
digestive tract morphogenesisGO:00485462310.028
response to carbohydrateGO:000974330.028
cell motilityGO:00488702440.027
negative regulation of response to stimulusGO:00485851040.027
embryo development ending in birth or egg hatchingGO:00097922710.027
morphogenesis of an epitheliumGO:00020093330.027
single organism localizationGO:19025782250.027
establishment of localizationGO:00512342440.027
response to chemicalGO:00422213200.027
response to abiotic stimulusGO:00096281220.027
rna metabolic processGO:00160702190.026
negative regulation of protein phosphorylationGO:000193340.026
oxoacid metabolic processGO:0043436310.026
immune system processGO:00023762410.026
carbohydrate biosynthetic processGO:001605110.026
single organism nuclear importGO:190259330.026
response to monosaccharideGO:003428430.026
protein targeting to nucleusGO:004474430.026
aromatic compound biosynthetic processGO:00194382170.026
organic substance biosynthetic processGO:19015762890.025
regulation of cytoplasmic transportGO:190364940.025
nucleic acid metabolic processGO:00903042440.025
regulation of protein localization to nucleusGO:190018020.025
cell migrationGO:00164772370.025
protein importGO:001703830.025
positive regulation of catabolic processGO:000989640.025
inositol lipid mediated signalingGO:004801720.025
positive regulation of biological processGO:00485182530.025
ameboidal type cell migrationGO:00016671430.025
growthGO:00400071740.025
cell matrix adhesionGO:000716040.025
regulation of rna metabolic processGO:00512522240.024
leukocyte proliferationGO:007066110.024
cellular amine metabolic processGO:004410620.023
regulation of cell substrate adhesionGO:001081010.023
transportGO:00068102200.023
organic cyclic compound biosynthetic processGO:19013622230.023
response to hexoseGO:000974630.023
generation of neuronsGO:00486993850.023
neuroblast proliferationGO:000740520.023
organic acid metabolic processGO:0006082310.023
regulation of cellular amino acid metabolic processGO:000652100.022
single organism metabolic processGO:00447102170.022
gastrulation with mouth forming secondGO:0001702440.022
small molecule catabolic processGO:004428230.022
programmed cell deathGO:00125011190.022
rna biosynthetic processGO:00327741810.022
deathGO:00162651210.022
carboxylic acid catabolic processGO:004639530.021
regulation of metabolic processGO:00192223590.021
heart developmentGO:00075073130.021
negative regulation of cytokine productionGO:000181810.021
lipid storageGO:001991510.021
regulation of protein catabolic processGO:004217610.021
regulation of nucleocytoplasmic transportGO:004682220.021
mononuclear cell proliferationGO:003294310.021
regulation of gene expressionGO:00104682650.021
protein acylationGO:004354330.021
regulation of cell differentiationGO:00455951420.021
meiotic nuclear divisionGO:000712640.021
synaptic growth at neuromuscular junctionGO:005112420.021
cellular response to nutrient levelsGO:003166920.021
regulation of rna biosynthetic processGO:20011412130.020
cellular component morphogenesisGO:00329893360.020
protein acetylationGO:000647320.020
positive regulation of cellular catabolic processGO:003133130.020
cellular amino acid metabolic processGO:000652070.020
intracellular signal transductionGO:0035556850.020
cell projection morphogenesisGO:00488582440.020
amino acid transportGO:000686520.020
negative regulation of catabolic processGO:000989530.019
chordate embryonic developmentGO:00430092710.019
mitochondrion organizationGO:000700540.019
regulation of mrna processingGO:005068430.019
transcription from rna polymerase ii promoterGO:0006366800.019
nuclear importGO:005117030.019
regulation of multicellular organismal developmentGO:20000262230.019
nucleobase containing compound biosynthetic processGO:00346542050.019
cell morphogenesis involved in differentiationGO:00009041950.019
regulation of cellular amine metabolic processGO:003323800.019
negative regulation of signalingGO:0023057960.019
regulation of cellular biosynthetic processGO:00313262450.019
cellular response to extracellular stimulusGO:003166820.019
neuron differentiationGO:00301823530.019
adherens junction organizationGO:003433240.019
regionalizationGO:00030022740.018
response to glucoseGO:000974930.018
cellular response to starvationGO:000926710.018
ion transmembrane transportGO:0034220910.018
organic acid catabolic processGO:001605430.018
regulation of anatomical structure morphogenesisGO:00226031300.018
regulation of primary metabolic processGO:00800903110.018
single organism transportGO:00447652060.018
regulation of cell activationGO:005086510.018
nucleobase containing compound metabolic processGO:00061392740.018
phosphatidylinositol 3 kinase signalingGO:001406520.018
regulation of cell shapeGO:000836010.018
gene expressionGO:00104672520.018
regulation of cell communicationGO:00106462320.018
regulation of response to stimulusGO:00485832690.018
determination of bilateral symmetryGO:00098552040.017
regulation of cellular ketone metabolic processGO:001056570.017
pericardium developmentGO:006003910.017
female sex differentiationGO:004666040.017
head developmentGO:00603223030.017
positive regulation of cell cycleGO:004578730.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
regulation of nucleoside metabolic processGO:000911820.017
multicellular organismal metabolic processGO:004423620.017
sensory organ developmentGO:00074233930.017
regulation of intracellular protein transportGO:003315730.017
zymogen activationGO:003163830.017
negative regulation of cell communicationGO:0010648960.017
carboxylic acid metabolic processGO:0019752220.017
positive regulation of cellular processGO:00485222010.017
hemopoiesisGO:00300971830.017
regulation of stem cell differentiationGO:200073640.016
blood vessel morphogenesisGO:00485142160.016
angiogenesisGO:00015251580.016
developmental growthGO:00485891660.016
protein metabolic processGO:00195381830.016
wound healingGO:0042060900.016
macromolecule biosynthetic processGO:00090592270.016
cell cycle g1 s phase transitionGO:004484310.016
negative regulation of ras protein signal transductionGO:004658010.016
small molecule metabolic processGO:0044281770.016
mitochondrial transportGO:000683920.016
convergent extensionGO:00600261180.016
muscle structure developmentGO:00610611960.016
modification dependent macromolecule catabolic processGO:004363230.016
embryonic organ developmentGO:00485683810.016
cellular ketone metabolic processGO:0042180110.016
cellular biosynthetic processGO:00442492860.016
ubiquitin dependent protein catabolic processGO:000651130.016
regulation of rho protein signal transductionGO:003502320.016
positive regulation of secretionGO:005104710.016
regulation of gtp catabolic processGO:003312420.016
extrinsic apoptotic signaling pathwayGO:009719130.016
internal protein amino acid acetylationGO:000647520.015
cell projection organizationGO:00300302840.015
regulation of macromolecule biosynthetic processGO:00105562250.015
peptide transportGO:001583310.015
organonitrogen compound metabolic processGO:1901564740.015
female gonad developmentGO:000858540.015
nucleic acid templated transcriptionGO:00976591810.015
energy reserve metabolic processGO:000611220.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
morphogenesis of an epithelial sheetGO:0002011490.015
regulation of transcription dna templatedGO:00063552130.015
positive regulation of cytokine productionGO:000181920.015
regulation of signalingGO:00230512350.015
adult behaviorGO:003053420.015
transcription dna templatedGO:00063511810.015
regulation of protein import into nucleusGO:004230620.015
positive regulation of cell adhesionGO:004578510.015
proteasomal protein catabolic processGO:001049820.015
transmembrane transportGO:00550851200.015
regulation of bindingGO:005109830.015
cell cycle arrestGO:000705010.015
regulation of biosynthetic processGO:00098892500.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
peptidyl lysine acetylationGO:001839420.014
cellular component disassemblyGO:002241110.014
cellular respirationGO:004533330.014
negative regulation of cellular metabolic processGO:0031324770.014
regulation of inflammatory responseGO:005072720.014
positive regulation of secretion by cellGO:190353210.014
regulation of tube sizeGO:003515020.014
single organism biosynthetic processGO:0044711710.014
regulation of gtpase activityGO:004308720.014
regulation of nucleotide catabolic processGO:003081120.014
negative regulation of defense responseGO:003134820.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
tissue regenerationGO:0042246740.014
determination of left right symmetryGO:00073681790.014
negative regulation of signal transductionGO:0009968940.014
response to external stimulusGO:00096052640.014
regulation of cell deathGO:00109411030.014
cell adhesionGO:0007155400.014
positive regulation of cytoskeleton organizationGO:005149530.014
eye developmentGO:00016542770.013
regulation of signal transductionGO:00099662250.013
hormone transportGO:000991420.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
cell part morphogenesisGO:00329902460.013
cellular protein catabolic processGO:004425740.013
camera type eye developmentGO:00430102220.013
l amino acid transportGO:001580710.013
neuron developmentGO:00486662620.013
regulation of apoptotic processGO:0042981980.013
internal peptidyl lysine acetylationGO:001839320.013
positive regulation of cellular metabolic processGO:0031325940.013
b cell mediated immunityGO:001972430.013
g1 s transition of mitotic cell cycleGO:000008210.013
ear developmentGO:00435831270.013
axonogenesisGO:00074091520.013
development of primary female sexual characteristicsGO:004654540.013
negative regulation of rna splicingGO:003311910.013
response to woundingGO:00096111160.013
positive regulation of metabolic processGO:00098931080.013
negative regulation of protein kinase activityGO:000646940.013
b cell activationGO:004211320.013
regulation of cell developmentGO:00602841000.013
response to stressGO:00069502630.013
regulation of muscle contractionGO:000693730.013
actin polymerization or depolymerizationGO:000815420.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
anterior posterior pattern specificationGO:00099521520.013
cellular component biogenesisGO:00440851780.013
cellular response to oxygen levelsGO:007145310.013
heterocycle biosynthetic processGO:00181302150.012
establishment of localization in cellGO:0051649770.012
tissue remodelingGO:004877140.012
cellular component assemblyGO:00226071700.012
gtp metabolic processGO:004603940.012
regulation of carbohydrate metabolic processGO:000610940.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of blood vessel sizeGO:005088020.012
rna localizationGO:000640340.012
negative regulation of kinase activityGO:003367340.012
dorsal motor nucleus of vagus nerve developmentGO:002174440.012
cellular response to external stimulusGO:007149620.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
astrocyte differentiationGO:004870810.012
regulation of purine nucleotide catabolic processGO:003312120.012
cell fate commitmentGO:0045165990.012
positive regulation of cell activationGO:005086710.012
guanosine containing compound catabolic processGO:190106920.012
positive regulation of cellular component biogenesisGO:004408930.012
negative regulation of macromolecule metabolic processGO:0010605760.012
gtp catabolic processGO:000618420.012
centrosome organizationGO:005129710.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
multi organism cellular processGO:004476420.012
organelle organizationGO:00069962270.012
cellular modified amino acid metabolic processGO:000657530.011
single organism organelle organizationGO:19025891990.011
cell deathGO:00082191210.011
macromolecule modificationGO:00434121110.011
neuronal action potentialGO:0019228180.011
negative regulation of mapk cascadeGO:004340940.011
positive regulation of cellular amine metabolic processGO:003324000.011
axon developmentGO:00615641660.011
action potentialGO:0001508190.011
chemotaxisGO:00069351040.011
neurological system processGO:0050877620.011
protein stabilizationGO:005082120.011
oxidative phosphorylationGO:000611910.011
positive regulation of nucleoside metabolic processGO:004597910.011
epibolyGO:0090504410.011
production of molecular mediator of immune responseGO:000244020.011
homeostatic processGO:00425921420.011
response to alkaloidGO:004327920.011
gliogenesisGO:0042063450.011
embryonic organ morphogenesisGO:00485622740.011
gland developmentGO:00487321430.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
regulation of neurogenesisGO:0050767870.011
cellular component assembly involved in morphogenesisGO:00109271070.011
carbohydrate homeostasisGO:003350010.011
forebrain developmentGO:0030900960.011
negative regulation of cellular catabolic processGO:003133030.011
germ line stem cell maintenanceGO:003071820.010
sensory perception of chemical stimulusGO:000760630.010
skeletal system developmentGO:00015011810.010
cellular localizationGO:0051641970.010
circulatory system processGO:0003013870.010
negative regulation of sequestering of calcium ionGO:005128340.010
rna 3 end processingGO:003112320.010
liver developmentGO:0001889960.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
connective tissue developmentGO:0061448990.010
hormone secretionGO:004687920.010
nucleobase containing compound transportGO:001593120.010
regulation of programmed cell deathGO:00430671010.010
multicellular organismal signalingGO:0035637220.010
meiotic cell cycle processGO:190304630.010
apoptotic processGO:00069151160.010
nucleic acid transportGO:005065720.010
somatic muscle developmentGO:000752540.010
guanosine containing compound metabolic processGO:190106840.010
regulation of transmembrane transporter activityGO:002289820.010
neuron projection developmentGO:00311751800.010
regulation of hormone secretionGO:004688320.010

fh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.082
inherited metabolic disorderDOID:65500.022
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.020
eye and adnexa diseaseDOID:149200.013
sensory system diseaseDOID:005015500.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
muscular diseaseDOID:008000000.012
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.011