Danio rerio

0 known processes

sort1a

sortilin 1a

(Aliases: sort1,zgc:85953)

sort1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.174
sensory organ developmentGO:00074233930.153
localization of cellGO:00516742440.112
cellular component movementGO:00069283350.092
striated muscle tissue developmentGO:00147061100.089
digestive tract developmentGO:00485652650.080
generation of neuronsGO:00486993850.078
regulation of multicellular organismal processGO:00512392770.076
digestive system developmentGO:00551232890.074
tube morphogenesisGO:00352393490.072
digestive tract morphogenesisGO:00485462310.071
system processGO:00030081850.067
central nervous system developmentGO:00074173870.066
regulation of reproductive processGO:200024140.064
negative regulation of cellular processGO:00485232830.062
regulation of synapse organizationGO:005080730.062
response to external stimulusGO:00096052640.061
chemotaxisGO:00069351040.058
regulation of signal transductionGO:00099662250.057
cell projection organizationGO:00300302840.053
positive regulation of biological processGO:00485182530.053
maintenance of locationGO:005123540.052
camera type eye developmentGO:00430102220.051
agingGO:000756820.051
taxisGO:00423301090.050
regulation of biological qualityGO:00650082630.048
regulation of synapse assemblyGO:005196330.048
hemopoiesisGO:00300971830.046
stem cell maintenanceGO:001982740.045
chemosensory behaviorGO:000763510.044
regulation of multicellular organism growthGO:004001440.044
lipid storageGO:001991510.044
cell migrationGO:00164772370.042
locomotionGO:00400113130.041
renal system developmentGO:0072001940.041
regulation of response to stimulusGO:00485832690.041
response to chemicalGO:00422213200.040
Mouse
regulation of developmental processGO:00507932470.040
single organism localizationGO:19025782250.039
Mouse
olfactory lobe developmentGO:002198840.039
single organism cell adhesionGO:0098602290.038
single organismal cell cell adhesionGO:0016337290.037
regulation of cell communicationGO:00106462320.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.036
endosomal transportGO:001619720.036
gastrulationGO:00073692080.036
cell substrate adhesionGO:003158940.036
negative regulation of synapse assemblyGO:005196420.035
signal transductionGO:00071654550.035
notochord developmentGO:0030903540.035
blood vessel developmentGO:00015682460.034
gland developmentGO:00487321430.034
single organism metabolic processGO:00447102170.034
positive regulation of blood circulationGO:190352420.034
positive regulation of transportGO:005105020.034
morphogenesis of an epitheliumGO:00020093330.033
spermatid developmentGO:000728620.033
axon guidanceGO:0007411860.033
neuron developmentGO:00486662620.032
mitochondrion organizationGO:000700540.031
angiogenesisGO:00015251580.031
neurological system processGO:0050877620.031
cognitionGO:005089010.031
cell motilityGO:00488702440.031
response to stressGO:00069502630.031
cortical cytoskeleton organizationGO:003086510.030
biological adhesionGO:0022610400.030
protein homooligomerizationGO:005126030.030
positive regulation of cell cycleGO:004578730.030
stem cell divisionGO:001714510.029
olfactory bulb developmentGO:002177240.029
spermatid differentiationGO:004851520.029
small molecule metabolic processGO:0044281770.029
regulation of multicellular organismal developmentGO:20000262230.029
purine ribonucleoside monophosphate catabolic processGO:000916940.028
positive regulation of cellular component biogenesisGO:004408930.028
meiotic nuclear divisionGO:000712640.028
regionalizationGO:00030022740.028
regulation of signalingGO:00230512350.027
synaptic growth at neuromuscular junctionGO:005112420.027
eye developmentGO:00016542770.027
heart developmentGO:00075073130.027
muscle structure developmentGO:00610611960.027
Mouse
neuron differentiationGO:00301823530.027
kidney developmentGO:0001822920.027
neuroblast proliferationGO:000740520.026
cellular component biogenesisGO:00440851780.026
cortical actin cytoskeleton organizationGO:003086610.025
regulation of metabolic processGO:00192223590.025
organonitrogen compound metabolic processGO:1901564740.024
vasculature developmentGO:00019442780.024
atp catabolic processGO:000620040.024
muscle organ developmentGO:00075171010.024
organic acid metabolic processGO:0006082310.024
adult behaviorGO:003053420.024
muscle cell developmentGO:00550011150.024
lateral inhibitionGO:004633110.023
multicellular organism growthGO:003526440.023
negative regulation of protein phosphorylationGO:000193340.023
dorsal ventral pattern formationGO:00099531250.023
guanosine containing compound metabolic processGO:190106840.023
synaptic vesicle localizationGO:009747910.023
cellular amine metabolic processGO:004410620.023
response to woundingGO:00096111160.023
embryo development ending in birth or egg hatchingGO:00097922710.023
fertilizationGO:000956630.023
regulation of establishment of protein localizationGO:007020140.023
embryonic organ developmentGO:00485683810.023
transportGO:00068102200.022
Mouse
phagocytosisGO:000690930.022
regulation of cell activationGO:005086510.022
organic substance biosynthetic processGO:19015762890.022
meiotic cell cycle processGO:190304630.022
cell surface receptor signaling pathwayGO:00071663250.021
regulation of cytokine productionGO:000181730.021
regulation of localizationGO:00328791040.021
cell part morphogenesisGO:00329902460.021
leukocyte proliferationGO:007066110.021
exocytosisGO:000688710.021
cartilage developmentGO:0051216960.021
gtp catabolic processGO:000618420.021
cellular amino acid metabolic processGO:000652070.021
muscle tissue developmentGO:00605371100.021
amine metabolic processGO:000930820.021
negative regulation of reproductive processGO:200024230.020
anterior posterior pattern specificationGO:00099521520.020
cellular component morphogenesisGO:00329893360.020
regulation of muscle contractionGO:000693730.020
actin filament polymerizationGO:003004120.020
axon developmentGO:00615641660.020
cellular response to chemical stimulusGO:00708871570.020
developmental growthGO:00485891660.020
regulation of erk1 and erk2 cascadeGO:007037240.020
regulation of cell shapeGO:000836010.020
cell adhesionGO:0007155400.020
regulation of blood vessel sizeGO:005088020.020
regulation of stem cell proliferationGO:007209120.020
neuronal action potentialGO:0019228180.020
adherens junction organizationGO:003433240.020
positive regulation of reproductive processGO:200024320.019
negative regulation of biological processGO:00485193040.019
mesoderm developmentGO:0007498880.019
synaptic vesicle transportGO:004848910.019
compound eye developmentGO:004874920.019
establishment of synaptic vesicle localizationGO:009748010.019
cellular component assemblyGO:00226071700.019
myotube differentiationGO:0014902450.019
Mouse
guanosine containing compound catabolic processGO:190106920.019
nucleoside monophosphate catabolic processGO:000912540.019
actin polymerization or depolymerizationGO:000815420.019
nucleocytoplasmic transportGO:000691340.019
positive regulation of cytoskeleton organizationGO:005149530.019
cell matrix adhesionGO:000716040.018
immune system developmentGO:00025201910.018
positive regulation of secretionGO:005104710.018
regulation of cytoplasmic transportGO:190364940.018
determination of left right symmetryGO:00073681790.018
stem cell proliferationGO:007208940.018
negative regulation of macromolecule metabolic processGO:0010605760.018
syncytium formation by plasma membrane fusionGO:0000768120.018
immune system processGO:00023762410.018
germ line stem cell maintenanceGO:003071820.018
purine nucleoside monophosphate catabolic processGO:000912840.018
regulation of protein transportGO:005122330.018
protein acetylationGO:000647320.018
protein localization to plasma membraneGO:007265910.018
neuron projection morphogenesisGO:00488121610.018
negative regulation of small gtpase mediated signal transductionGO:005105810.018
positive regulation of cell adhesionGO:004578510.018
response to alkaloidGO:004327920.018
positive regulation of cell activationGO:005086710.018
regulation of cellular amine metabolic processGO:003323800.017
regulation of protein complex assemblyGO:004325430.017
lymphocyte proliferationGO:004665110.017
single fertilizationGO:000733830.017
neuron projection guidanceGO:0097485860.017
single organism nuclear importGO:190259330.017
mononuclear cell proliferationGO:003294310.017
positive regulation of cellular processGO:00485222010.017
organelle organizationGO:00069962270.017
Mouse
response to carbohydrateGO:000974330.017
actin filament based processGO:0030029640.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
regulation of syncytium formation by plasma membrane fusionGO:006014220.017
rna localizationGO:000640340.017
internal protein amino acid acetylationGO:000647520.017
regulation of bindingGO:005109830.016
single organism organelle organizationGO:19025891990.016
positive regulation of cytokine productionGO:000181920.016
response to organic substanceGO:00100331530.016
Mouse
positive regulation of secretion by cellGO:190353210.016
membrane fusionGO:006102520.016
regulation of neurological system processGO:003164420.016
erk1 and erk2 cascadeGO:007037140.016
oxoacid metabolic processGO:0043436310.016
deathGO:00162651210.016
female sex differentiationGO:004666040.016
gtp metabolic processGO:004603940.016
embryonic organ morphogenesisGO:00485622740.016
multi organism processGO:00517041340.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of catabolic processGO:000989640.016
blood vessel morphogenesisGO:00485142160.016
regulation of protein polymerizationGO:003227120.016
signal transduction in absence of ligandGO:003803410.016
response to abiotic stimulusGO:00096281220.016
axonogenesisGO:00074091520.016
protein import into nucleusGO:000660630.015
actin cytoskeleton organizationGO:0030036630.015
striated muscle cell developmentGO:00550021080.015
cell morphogenesisGO:00009022890.015
single organism membrane fusionGO:004480120.015
nuclear transportGO:005116940.015
regulation of cellular metabolic processGO:00313233200.015
extracellular structure organizationGO:0043062270.015
cellular macromolecule metabolic processGO:00442603910.015
heart morphogenesisGO:00030071560.015
smooth muscle contractionGO:000693920.015
regulation of intracellular protein transportGO:003315730.015
establishment of protein localization to organelleGO:007259440.015
protein polymerizationGO:005125840.015
forebrain cell migrationGO:002188510.015
phosphorus metabolic processGO:00067931090.015
establishment of protein localization to plasma membraneGO:009000210.015
regulation of protein catabolic processGO:004217610.015
cellular extravasationGO:004512310.015
cytoskeleton dependent cytokinesisGO:006164030.015
cell projection morphogenesisGO:00488582440.015
regulation of inflammatory responseGO:005072720.014
camera type eye morphogenesisGO:00485931080.014
nuclear importGO:005117030.014
cytoskeleton organizationGO:0007010960.014
blood circulationGO:0008015870.014
intracellular receptor signaling pathwayGO:0030522300.014
protein targeting to nucleusGO:004474430.014
regulation of neural precursor cell proliferationGO:200017730.014
multicellular organismal response to stressGO:003355520.014
striated muscle cell differentiationGO:00511461290.014
Mouse
nitrogen compound metabolic processGO:00068073190.014
protein localization to nucleusGO:003450430.014
cellular biosynthetic processGO:00442492860.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
positive regulation of chromosome organizationGO:200125210.014
pronephros developmentGO:0048793690.014
cytoplasm organizationGO:000702840.014
nucleic acid templated transcriptionGO:00976591810.014
peptidyl lysine acetylationGO:001839420.014
regulation of oocyte developmentGO:006028130.014
negative regulation of ras protein signal transductionGO:004658010.014
negative regulation of signalingGO:0023057960.014
ovulation cycleGO:004269820.014
regulation of synaptic plasticityGO:004816710.014
protein importGO:001703830.014
proteasomal protein catabolic processGO:001049820.013
cell deathGO:00082191210.013
ovulation cycle processGO:002260220.013
phosphate containing compound metabolic processGO:00067961080.013
regulation of cell deathGO:00109411030.013
positive regulation of cell divisionGO:005178120.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
skeletal muscle tissue developmentGO:0007519670.013
biosynthetic processGO:00090582940.013
internal peptidyl lysine acetylationGO:001839320.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
positive regulation of protein complex assemblyGO:003133420.013
nucleobase containing compound metabolic processGO:00061392740.013
protein metabolic processGO:00195381830.013
negative regulation of signal transductionGO:0009968940.013
cellular nitrogen compound metabolic processGO:00346412900.013
programmed cell deathGO:00125011190.013
cellular component disassemblyGO:002241110.013
positive regulation of immune effector processGO:000269930.013
regulation of protein localization to plasma membraneGO:190307610.013
response to uvGO:000941130.013
multicellular organismal signalingGO:0035637220.013
carboxylic acid metabolic processGO:0019752220.013
small gtpase mediated signal transductionGO:000726480.013
forebrain developmentGO:0030900960.013
cellular protein catabolic processGO:004425740.013
skeletal muscle organ developmentGO:0060538780.013
urogenital system developmentGO:0001655970.013
cellular response to external stimulusGO:007149620.013
regulation of apoptotic processGO:0042981980.013
response to hexoseGO:000974630.013
cellular response to lipopolysaccharideGO:007122230.012
macromolecule deacylationGO:009873230.012
negative regulation of protein kinase activityGO:000646940.012
cell cell signalingGO:0007267520.012
development of primary female sexual characteristicsGO:004654540.012
positive regulation of macromolecule metabolic processGO:0010604930.012
nucleobase containing compound transportGO:001593120.012
growthGO:00400071740.012
regulation of cell adhesionGO:0030155150.012
apoptotic processGO:00069151160.012
regulation of tube sizeGO:003515020.012
lipid metabolic processGO:0006629520.012
alcohol biosynthetic processGO:004616520.012
circulatory system processGO:0003013870.012
spinal cord motor neuron differentiationGO:0021522260.012
cell migration involved in gastrulationGO:0042074790.012
peptidyl threonine modificationGO:001821010.012
post embryonic organ developmentGO:004856940.012
regulation of epithelial cell proliferationGO:005067830.012
neuromuscular synaptic transmissionGO:000727420.012
regulation of cellular amino acid metabolic processGO:000652100.012
cellular carbohydrate metabolic processGO:004426240.012
positive regulation of cellular catabolic processGO:003133130.012
regulation of neurotransmitter transportGO:005158810.012
ras protein signal transductionGO:000726570.011
pole plasm assemblyGO:000731540.011
response to nutrientGO:000758430.011
regulation of locomotionGO:0040012550.011
regulation of cellular component movementGO:0051270550.011
regulation of cell migrationGO:0030334400.011
protein acylationGO:004354330.011
myoblast fusionGO:0007520100.011
glial cell migrationGO:000834730.011
carbohydrate homeostasisGO:003350010.011
modification dependent macromolecule catabolic processGO:004363230.011
neuron remodelingGO:001632210.011
regulation of myotube differentiationGO:001083020.011
membrane invaginationGO:001032410.011
protein complex subunit organizationGO:0071822460.011
organelle localizationGO:0051640490.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
inositol lipid mediated signalingGO:004801720.011
determination of bilateral symmetryGO:00098552040.011
macromolecule biosynthetic processGO:00090592270.011
regulation of nucleocytoplasmic transportGO:004682220.011
homeostatic processGO:00425921420.011
positive regulation of map kinase activityGO:004340630.011
cell substrate junction assemblyGO:000704420.011
startle responseGO:000196440.011
establishment of endothelial barrierGO:006102830.011
synaptic transmissionGO:0007268350.011
cellular ketone metabolic processGO:0042180110.011
head developmentGO:00603223030.011
sensory perception of chemical stimulusGO:000760630.011
regulation of mrna processingGO:005068430.011
glucose homeostasisGO:004259310.011
intracellular signal transductionGO:0035556850.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
heterocycle metabolic processGO:00464832900.011
response to glucoseGO:000974930.011
brain developmentGO:00074202930.011
positive regulation of dna metabolic processGO:005105410.011
specification of symmetryGO:00097992040.011
regulation of gtpase activityGO:004308720.011
lateral line system developmentGO:0048925760.010
regulation of programmed cell deathGO:00430671010.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
catechol containing compound metabolic processGO:000971220.010
response to monosaccharideGO:003428430.010
regulation of establishment of protein localization to plasma membraneGO:009000310.010
regulation of bone remodelingGO:004685020.010
synaptic vesicle endocytosisGO:004848810.010
response to nicotineGO:003509420.010
embryonic skeletal system morphogenesisGO:0048704930.010
positive regulation of exocytosisGO:004592110.010
catecholamine metabolic processGO:000658420.010
negative regulation of kinase activityGO:003367340.010
cell morphogenesis involved in neuron differentiationGO:00486671630.010
response to inorganic substanceGO:0010035380.010
actin filament based movementGO:003004810.010
muscle cell differentiationGO:00426921390.010
Mouse
cellular aromatic compound metabolic processGO:00067252950.010
nucleic acid transportGO:005065720.010
regulation of tissue remodelingGO:003410320.010
convergent extensionGO:00600261180.010
skeletal system developmentGO:00015011810.010
post golgi vesicle mediated transportGO:000689210.010
regulation of nucleoside metabolic processGO:000911820.010
regulation of macromolecule metabolic processGO:00602553170.010
positive regulation of cellular amino acid metabolic processGO:004576400.010

sort1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.020
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011