Danio rerio

63 known processes

lmx1b.2

LIM homeobox transcription factor 1, beta 2

lmx1b.2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pronephric glomerulus developmentGO:0039021130.987
midbrain hindbrain boundary developmentGO:0030917230.981
neural tube patterningGO:0021532330.943
chordate embryonic developmentGO:00430092710.877
embryo development ending in birth or egg hatchingGO:00097922710.874
central nervous system myelinationGO:002201020.828
central nervous system developmentGO:00074173870.828
generation of neuronsGO:00486993850.819
brain developmentGO:00074202930.799
regionalizationGO:00030022740.773
rostrocaudal neural tube patterningGO:0021903290.750
pancreatic d cell developmentGO:000332410.711
closure of optic fissureGO:006138660.658
tube morphogenesisGO:00352393490.620
optomotor responseGO:007163210.574
sensory system developmentGO:0048880760.573
lateral line system developmentGO:0048925760.557
pronephric nephron developmentGO:0039019140.549
nucleic acid templated transcriptionGO:00976591810.532
central nervous system myelin formationGO:003228910.528
heart developmentGO:00075073130.495
embryonic organ morphogenesisGO:00485622740.486
optic cup morphogenesis involved in camera type eye developmentGO:000207270.483
skin developmentGO:0043588540.418
cellular amino acid biosynthetic processGO:000865220.414
head developmentGO:00603223030.411
sensory organ developmentGO:00074233930.396
gene expressionGO:00104672520.388
midbrain developmentGO:0030901280.386
neural precursor cell proliferationGO:0061351200.377
cell fate commitmentGO:0045165990.374
lateral line developmentGO:0048882660.370
cellular nitrogen compound metabolic processGO:00346412900.356
type b pancreatic cell developmentGO:000332340.350
epidermal cell differentiationGO:0009913360.336
posterior lateral line developmentGO:0048916380.333
pancreatic a cell developmentGO:000332220.332
camera type eye morphogenesisGO:00485931080.332
cell motilityGO:00488702440.331
appendage developmentGO:0048736800.320
peripheral nervous system developmentGO:0007422550.318
anterior posterior pattern specificationGO:00099521520.306
rhombomere developmentGO:0021546190.302
peripheral nervous system neuron axonogenesisGO:0048936130.301
embryonic limb morphogenesisGO:003032620.296
positive regulation of cellular processGO:00485222010.296
fourth ventricle developmentGO:002159280.290
axial mesoderm developmentGO:0048318100.289
embryonic organ developmentGO:00485683810.285
otic placode formationGO:0043049230.283
single organism reproductive processGO:0044702400.270
neural tube developmentGO:0021915620.269
regulation of nucleic acid templated transcriptionGO:19035062130.262
hemopoiesisGO:00300971830.254
cell fate specificationGO:0001708680.249
neuron developmentGO:00486662620.248
negative regulation of biological processGO:00485193040.246
embryonic camera type eye formationGO:0060900100.244
cellular nitrogen compound biosynthetic processGO:00442712180.243
ear morphogenesisGO:0042471640.242
retinal ganglion cell axon guidanceGO:0031290350.237
camera type eye developmentGO:00430102220.221
lateral line ganglion developmentGO:004889020.220
cellular macromolecule biosynthetic processGO:00346452240.220
localization of cellGO:00516742440.218
signal transductionGO:00071654550.211
gamete generationGO:0007276330.209
regulation of collateral sprouting in absence of injuryGO:004869640.204
nitrogen compound metabolic processGO:00068073190.195
neuroblast differentiationGO:001401610.194
cardiac muscle tissue developmentGO:0048738480.193
pancreatic d cell differentiationGO:000331120.192
organic acid metabolic processGO:0006082310.191
pectoral fin developmentGO:0033339500.189
neuroblast proliferationGO:000740520.189
embryonic eye morphogenesisGO:0048048300.186
developmental process involved in reproductionGO:0003006270.185
negative regulation of cellular biosynthetic processGO:0031327550.184
columnar cuboidal epithelial cell differentiationGO:0002065380.183
neuron differentiationGO:00301823530.181
stem cell proliferationGO:007208940.179
sensory organ morphogenesisGO:00905962000.178
myelin assemblyGO:003228810.174
pigment cell differentiationGO:0050931380.173
auditory receptor cell developmentGO:006011780.172
nucleobase containing compound biosynthetic processGO:00346542050.170
heterocycle biosynthetic processGO:00181302150.162
axon ensheathment in central nervous systemGO:003229120.160
ectodermal placode developmentGO:0071696370.157
hatching gland developmentGO:004878530.154
establishment of localizationGO:00512342440.151
endoderm developmentGO:0007492490.142
ear developmentGO:00435831270.139
morphogenesis of embryonic epitheliumGO:0016331300.138
locomotionGO:00400113130.138
otic vesicle morphogenesisGO:0071600340.136
eye developmentGO:00016542770.133
thalamus developmentGO:002179460.132
posterior lateral line system developmentGO:0048915460.131
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.131
cell migrationGO:00164772370.130
negative regulation of cellular metabolic processGO:0031324770.129
regulation of nitrogen compound metabolic processGO:00511712510.125
hepatocyte proliferationGO:007257420.122
cell proliferationGO:0008283800.121
mechanosensory lateral line system developmentGO:0048881490.121
embryonic camera type eye developmentGO:0031076290.120
oocyte maturationGO:000155640.120
ectodermal placode morphogenesisGO:0071697320.116
cellular component movementGO:00069283350.114
gliogenesisGO:0042063450.112
regulation of transcription dna templatedGO:00063552130.107
fin morphogenesisGO:0033334530.103
regulation of developmental processGO:00507932470.103
defense responseGO:0006952470.102
axon extensionGO:0048675450.101
blood circulationGO:0008015870.100
type b pancreatic cell differentiationGO:000330980.099
gland developmentGO:00487321430.098
regulation of axonogenesisGO:0050770320.098
cell proliferation in forebrainGO:002184630.097
forebrain regionalizationGO:002187140.097
lateral line nerve developmentGO:004889290.097
hindbrain formationGO:002157630.096
regulation of rna biosynthetic processGO:20011412130.096
intracellular signal transductionGO:0035556850.096
reproductive processGO:0022414400.096
atrial cardiac muscle cell differentiationGO:005501150.093
negative regulation of transcription dna templatedGO:0045892450.093
cartilage developmentGO:0051216960.092
lateral line nerve glial cell developmentGO:004893760.091
epithelial cell differentiationGO:00308551160.091
inner ear developmentGO:00488391260.089
exocrine pancreas developmentGO:0031017280.089
neuron neuron synaptic transmissionGO:000727010.088
medial fin developmentGO:0033338160.088
regulation of stem cell proliferationGO:007209120.088
chemotaxisGO:00069351040.088
regulation of signalingGO:00230512350.087
artery developmentGO:0060840220.087
positive regulation of gastrulationGO:200054320.087
neuromast depositionGO:004888590.087
rna biosynthetic processGO:00327741810.086
protein localization to nucleusGO:003450430.086
cell morphogenesis involved in neuron differentiationGO:00486671630.085
ventral midline developmentGO:0007418130.085
somitogenesisGO:0001756870.084
cerebellum formationGO:002158820.084
negative regulation of cellular processGO:00485232830.083
ventricular system developmentGO:0021591120.082
cell deathGO:00082191210.082
regulation of nucleobase containing compound metabolic processGO:00192192500.082
heterocycle metabolic processGO:00464832900.081
enzyme linked receptor protein signaling pathwayGO:00071671060.080
nephron morphogenesisGO:007202820.080
embryonic retina morphogenesis in camera type eyeGO:0060059220.080
larval developmentGO:000216420.080
nucleic acid metabolic processGO:00903042440.079
rhombomere formationGO:0021594120.079
retina morphogenesis in camera type eyeGO:0060042790.078
regulation of gene expressionGO:00104682650.077
negative regulation of nucleobase containing compound metabolic processGO:0045934590.077
growthGO:00400071740.077
brain morphogenesisGO:0048854180.076
glial cell differentiationGO:0010001420.076
epidermal cell fate specificationGO:000995740.076
blood vessel developmentGO:00015682460.074
rhombomere boundary formationGO:0021654100.073
hindbrain developmentGO:0030902910.073
nose developmentGO:004358430.073
neural tube formationGO:0001841160.072
regulation of organ growthGO:004662030.072
aorta developmentGO:003590440.072
leukocyte differentiationGO:0002521250.072
female sex differentiationGO:004666040.071
cell morphogenesis involved in differentiationGO:00009041950.070
pigmentationGO:0043473850.070
carboxylic acid metabolic processGO:0019752220.070
glial cell developmentGO:0021782200.069
regulation of cell developmentGO:00602841000.068
regulation of endodermal cell fate specificationGO:0042663150.068
glomerulus morphogenesisGO:007210270.067
retina development in camera type eyeGO:00600411460.067
digestive system developmentGO:00551232890.067
maintenance of locationGO:005123540.065
organonitrogen compound metabolic processGO:1901564740.065
oxoacid metabolic processGO:0043436310.065
negative regulation of rna biosynthetic processGO:1902679450.065
endocrine system developmentGO:0035270650.064
cellular amine metabolic processGO:004410620.063
blood vessel morphogenesisGO:00485142160.063
inner ear morphogenesisGO:0042472630.062
hair cell differentiationGO:0035315320.062
morphogenesis of an epitheliumGO:00020093330.061
programmed cell deathGO:00125011190.061
rhombomere 5 developmentGO:002157140.060
positive regulation of neural precursor cell proliferationGO:200017910.059
cardiac cell fate commitmentGO:006091110.058
single organism metabolic processGO:00447102170.058
regulation of sequestering of calcium ionGO:005128240.058
appendage morphogenesisGO:0035107560.058
neuron projection morphogenesisGO:00488121610.058
determination of bilateral symmetryGO:00098552040.058
formation of primary germ layerGO:0001704620.057
anterior head developmentGO:009706520.056
otolith developmentGO:0048840320.056
developmental growthGO:00485891660.056
otic vesicle formationGO:0030916270.056
neuromast developmentGO:0048884460.056
biosynthetic processGO:00090582940.056
regulation of macromolecule biosynthetic processGO:00105562250.056
embryonic viscerocranium morphogenesisGO:0048703520.055
notch signaling pathwayGO:0007219350.055
macromolecule modificationGO:00434121110.055
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.054
regulation of primary metabolic processGO:00800903110.054
exocrine system developmentGO:0035272280.053
otic vesicle developmentGO:0071599420.053
positive regulation of stem cell proliferationGO:200064810.053
cerebellar granular layer formationGO:002168430.053
positive regulation of cellular component biogenesisGO:004408930.053
erk1 and erk2 cascadeGO:007037140.051
transcription dna templatedGO:00063511810.051
specification of organ identityGO:001009220.051
positive regulation of map kinase activityGO:004340630.051
epithelial cell proliferation involved in liver morphogenesisGO:007257520.050
regulation of biological qualityGO:00650082630.050
amine metabolic processGO:000930820.049
oligodendrocyte differentiationGO:0048709230.048
olfactory lobe developmentGO:002198840.048
regulation of multicellular organism growthGO:004001440.048
neural plate pattern specificationGO:0060896120.048
tube closureGO:006060610.048
regulation of multicellular organismal processGO:00512392770.048
dopaminergic neuron differentiationGO:0071542140.048
embryonic skeletal system developmentGO:0048706970.048
multicellular organismal reproductive processGO:0048609350.048
lipid storageGO:001991510.047
neuron fate specificationGO:0048665200.047
ectodermal placode formationGO:0060788260.047
cerebellum morphogenesisGO:0021587100.047
organic cyclic compound metabolic processGO:19013603010.047
regulation of anatomical structure morphogenesisGO:00226031300.047
b cell activationGO:004211320.047
rna metabolic processGO:00160702190.047
peripheral nervous system neuron developmentGO:0048935220.046
regulation of cell shapeGO:000836010.046
water homeostasisGO:003010440.046
regulation of biosynthetic processGO:00098892500.046
positive regulation of rna metabolic processGO:0051254590.045
regulation of transcription from rna polymerase ii promoterGO:00063571140.045
neuron projection developmentGO:00311751800.045
apoptotic process involved in morphogenesisGO:006056120.045
negative regulation of nucleic acid templated transcriptionGO:1903507450.044
regulation of cellular component organizationGO:0051128860.044
cell part morphogenesisGO:00329902460.044
gall bladder developmentGO:006101010.044
cellular protein metabolic processGO:00442671290.044
regulation of neuron differentiationGO:0045664560.044
negative regulation of nitrogen compound metabolic processGO:0051172590.044
regulation of multicellular organismal developmentGO:20000262230.043
organic substance biosynthetic processGO:19015762890.043
cellular macromolecule metabolic processGO:00442603910.043
pancreas developmentGO:0031016840.043
vestibular receptor cell differentiationGO:006011430.042
regulation of cysteine type endopeptidase activityGO:2000116210.042
developmental cell growthGO:0048588520.042
lateral line nerve glial cell differentiationGO:004889560.042
tube formationGO:0035148250.042
regulation of neurogenesisGO:0050767870.041
circulatory system processGO:0003013870.041
vestibular receptor cell developmentGO:006011830.041
regulation of cellular metabolic processGO:00313233200.041
regulation of extent of cell growthGO:0061387290.041
phosphatidylinositol 3 kinase signalingGO:001406520.041
neural plate morphogenesisGO:000183970.040
auditory receptor cell differentiationGO:0042491150.040
positive regulation of histone modificationGO:003105810.040
negative regulation of endopeptidase activityGO:0010951100.039
mechanoreceptor differentiationGO:0042490370.039
multicellular organism growthGO:003526440.038
optic placode formation involved in camera type eye formationGO:004661930.038
cranial ganglion developmentGO:006155030.038
regulation of catalytic activityGO:0050790550.038
transmembrane transportGO:00550851200.038
pronephric glomerulus morphogenesisGO:003577560.038
pectoral fin morphogenesisGO:0035138290.038
apoptotic processGO:00069151160.038
melanocyte differentiationGO:0030318260.037
nerve developmentGO:0021675450.037
cilium movementGO:0003341260.037
hematopoietic or lymphoid organ developmentGO:00485341910.037
regulation of neural precursor cell proliferationGO:200017730.037
eye morphogenesisGO:00485921440.037
hard palate developmentGO:006002240.037
striated muscle tissue developmentGO:00147061100.036
b cell differentiationGO:003018310.036
glandular epithelial cell differentiationGO:000206790.036
development of primary female sexual characteristicsGO:004654540.036
somatic cell dna recombinationGO:001644410.036
embryonic cranial skeleton morphogenesisGO:0048701900.036
urogenital system developmentGO:0001655970.036
sequestering of metal ionGO:005123830.035
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.035
embryonic camera type eye morphogenesisGO:0048596190.035
muscle structure developmentGO:00610611960.035
determination of left right symmetryGO:00073681790.035
regulation of cellular macromolecule biosynthetic processGO:20001122220.035
cell morphogenesisGO:00009022890.034
protein metabolic processGO:00195381830.034
sympathetic nervous system developmentGO:004848530.034
regulation of macromolecule metabolic processGO:00602553170.034
regulation of retina development in camera type eyeGO:190286620.033
system processGO:00030081850.033
epidermis developmentGO:0008544480.033
microtubule based processGO:0007017600.033
mesoderm developmentGO:0007498880.033
embryonic heart tube morphogenesisGO:00031431080.033
response to growth factorGO:0070848390.033
artery morphogenesisGO:0048844140.033
transportGO:00068102200.033
taxisGO:00423301090.032
cellular protein modification processGO:00064641000.032
monoamine transportGO:001584410.032
metencephalon developmentGO:0022037270.032
midbrain hindbrain boundary morphogenesisGO:002155550.031
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.031
cerebellar granular layer developmentGO:002168130.031
embryonic skeletal system morphogenesisGO:0048704930.031
heart processGO:0003015710.031
cerebellum developmentGO:0021549170.031
adherens junction organizationGO:003433240.031
sulfur compound transportGO:007234830.031
regulation of organelle organizationGO:0033043290.030
cardiocyte differentiationGO:0035051440.030
single organism biosynthetic processGO:0044711710.030
positive regulation of neuron differentiationGO:0045666120.030
regulation of cell morphogenesis involved in differentiationGO:0010769380.030
forebrain morphogenesisGO:004885360.030
nucleocytoplasmic transportGO:000691340.030
glomerulus developmentGO:0032835270.030
hepatic duct developmentGO:006101120.030
peripheral nervous system neuron differentiationGO:0048934280.030
regulation of cellular response to growth factor stimulusGO:0090287350.030
formation of anatomical boundaryGO:0048859140.029
cellular aromatic compound metabolic processGO:00067252950.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.029
negative regulation of nuclear divisionGO:005178430.029
nuclear transportGO:005116940.029
dorsal ventral pattern formationGO:00099531250.029
neuron fate commitmentGO:0048663260.029
gastrulationGO:00073692080.029
post anal tail morphogenesisGO:0036342190.029
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.029
regulation of cell communicationGO:00106462320.029
mesoderm morphogenesisGO:0048332510.029
ectoderm developmentGO:000739890.028
single organism transportGO:00447652060.028
multicellular organismal signalingGO:0035637220.028
neuromast primordium migrationGO:0048883120.028
cell projection morphogenesisGO:00488582440.028
response to organic substanceGO:00100331530.028
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.028
muscle cell differentiationGO:00426921390.028
macromolecular complex subunit organizationGO:0043933740.028
aromatic compound biosynthetic processGO:00194382170.028
multicellular organism reproductionGO:0032504350.028
sodium ion transportGO:0006814240.028
axon developmentGO:00615641660.028
epibolyGO:0090504410.028
rhombomere 6 developmentGO:002157240.028
positive regulation of cell cycleGO:004578730.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
axonogenesisGO:00074091520.028
nucleobase containing compound metabolic processGO:00061392740.028
regulation of reproductive processGO:200024140.028
cellular response to stressGO:0033554620.027
muscle tissue developmentGO:00605371100.027
neural plate regionalizationGO:0060897100.027
embryonic appendage morphogenesisGO:0035113300.027
apoptotic process involved in developmentGO:190274220.027
female gonad developmentGO:000858540.027
wnt signaling pathwayGO:0016055800.027
developmental programmed cell deathGO:001062340.027
cell proliferation in hindbrainGO:002153440.026
regulation of stem cell differentiationGO:200073640.026
response to endogenous stimulusGO:0009719830.026
germ cell migrationGO:000835480.026
regulation of anterior head developmentGO:200074220.026
stem cell fate determinationGO:004886710.026
otolith morphogenesisGO:003247480.026
negative regulation of developmental processGO:0051093650.025
nephron tubule morphogenesisGO:007207810.025
indole containing compound metabolic processGO:004243020.025
positive regulation of cell fate commitmentGO:001045510.025
cerebellar granule cell differentiationGO:002170730.025
neuroepithelial cell differentiationGO:0060563260.025
phagocytosisGO:000690930.025
regulation of rna metabolic processGO:00512522240.025
cellular amino acid metabolic processGO:000652070.024
action potentialGO:0001508190.024
phosphate containing compound metabolic processGO:00067961080.024
regulation of vascular permeabilityGO:004311450.024
nephron developmentGO:0072006310.024
endodermal cell fate determinationGO:000749320.024
central nervous system neuron differentiationGO:0021953740.024
regulation of circadian rhythmGO:004275240.024
regulation of cell differentiationGO:00455951420.024
positive regulation of cell adhesionGO:004578510.023
rhombomere morphogenesisGO:0021593170.023
organelle organizationGO:00069962270.023
angioblast cell migration involved in selective angioblast sproutingGO:003547540.023
negative regulation of cytoplasmic transportGO:190365020.023
negative regulation of protein kinase activityGO:000646940.023
single organism localizationGO:19025782250.023
stem cell fate commitmentGO:004886510.023
embryonic heart tube developmentGO:00350501330.023
neuron projection guidanceGO:0097485860.023
humoral immune response mediated by circulating immunoglobulinGO:000245530.023
cell differentiation in spinal cordGO:0021515400.023
inner ear receptor cell fate commitmentGO:006012040.023
neuroblast fate determinationGO:000740010.023
membrane fusionGO:006102520.023
cellular biosynthetic processGO:00442492860.023
negative regulation of collateral sprouting of intact axon in response to injuryGO:004868520.023
regulation of cardiac muscle tissue developmentGO:005502410.023
regulation of endodermal cell differentiationGO:1903224150.023
stem cell maintenanceGO:001982740.022
proteolysisGO:0006508380.022
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.022
odontogenesis of dentin containing toothGO:004247510.022
covalent chromatin modificationGO:0016569200.022
locus ceruleus developmentGO:002170330.022
lens development in camera type eyeGO:0002088220.022
stem cell differentiationGO:00488631170.022
endocrine pancreas developmentGO:0031018270.022
cellular carbohydrate metabolic processGO:004426240.022
transmission of nerve impulseGO:0019226190.022
negative regulation of striated muscle tissue developmentGO:004584320.021
cellular protein catabolic processGO:004425740.021
positive regulation of nervous system developmentGO:0051962250.021
regulation of metabolic processGO:00192223590.021
positive regulation of gene expressionGO:0010628710.021
endocardium formationGO:006021410.021
negative regulation of intracellular transportGO:003238730.021
spinal cord anterior posterior patterningGO:002151210.021
collagen fibril organizationGO:003019910.021
agingGO:000756820.021
negative regulation of biosynthetic processGO:0009890550.021
small molecule metabolic processGO:0044281770.020
cellular response to endogenous stimulusGO:0071495680.020
establishment of mitotic spindle orientationGO:0000132100.020
cellular component biogenesisGO:00440851780.020
macromolecule biosynthetic processGO:00090592270.020
histone deacetylationGO:001657520.020
somite developmentGO:0061053960.020
regulation of wnt signaling pathwayGO:0030111530.020
regulation of purine nucleotide catabolic processGO:003312120.020
negative regulation of macromolecule metabolic processGO:0010605760.020
osteoclast differentiationGO:003031610.020
organ formationGO:0048645170.020
sex determinationGO:000753010.020
neural plate anterior posterior regionalizationGO:002199980.020
negative regulation of intracellular protein transportGO:009031730.020
mesenchyme developmentGO:00604851270.019
cell growthGO:0016049570.019
determination of heart left right asymmetryGO:00613711170.019
auditory receptor cell fate commitmentGO:000991240.019
positive regulation of macromolecule metabolic processGO:0010604930.019
cell differentiation in hindbrainGO:002153350.019
regulation of photoreceptor cell differentiationGO:004653220.019
regulation of cellular ketone metabolic processGO:001056570.019
nuclear importGO:005117030.019
anterior commissure morphogenesisGO:002196030.019
neurological system processGO:0050877620.019
epithelial cell developmentGO:0002064420.019
hindbrain morphogenesisGO:0021575220.019
collateral sprouting in absence of injuryGO:004866940.019
regulation of cellular amine metabolic processGO:003323800.019
canonical wnt signaling pathwayGO:0060070480.019
regulation of catenin import into nucleusGO:003541220.019
macromolecule localizationGO:0033036540.018
regulation of protein transportGO:005122330.018
response to woundingGO:00096111160.018
posterior lateral line neuromast developmentGO:0048919200.018
cell proliferation in midbrainGO:003327840.018
regulation of apoptotic processGO:0042981980.018
positive regulation of muscle tissue developmentGO:190186310.018
anatomical structure homeostasisGO:0060249360.018

lmx1b.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
reproductive system diseaseDOID:1500.181
disease of anatomical entityDOID:700.181
endocrine system diseaseDOID:2800.037
disease of cellular proliferationDOID:1456600.035
organ system cancerDOID:005068600.035
cancerDOID:16200.035