Danio rerio

33 known processes

smoc1

SPARC related modular calcium binding 1

smoc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular processGO:00485232830.556
embryonic organ developmentGO:00485683810.528
regulation of cellular macromolecule biosynthetic processGO:20001122220.484
regulation of signalingGO:00230512350.448
cellular macromolecule metabolic processGO:00442603910.436
regulation of nucleobase containing compound metabolic processGO:00192192500.399
regulation of macromolecule metabolic processGO:00602553170.398
negative regulation of biological processGO:00485193040.390
nitrogen compound metabolic processGO:00068073190.369
regulation of metabolic processGO:00192223590.362
organic substance biosynthetic processGO:19015762890.341
regulation of signal transductionGO:00099662250.313
regulation of response to stimulusGO:00485832690.310
morphogenesis of an epitheliumGO:00020093330.301
cognitionGO:005089010.262
biosynthetic processGO:00090582940.250
oxoacid metabolic processGO:0043436310.222
lipid storageGO:001991510.210
regulation of cellular metabolic processGO:00313233200.209
axonogenesisGO:00074091520.204
rna biosynthetic processGO:00327741810.199
regulation of cell communicationGO:00106462320.198
embryonic organ morphogenesisGO:00485622740.197
multicellular organismal signalingGO:0035637220.197
central nervous system developmentGO:00074173870.194
regulation of primary metabolic processGO:00800903110.187
cellular biosynthetic processGO:00442492860.182
regulation of transcription dna templatedGO:00063552130.181
heterocycle biosynthetic processGO:00181302150.174
aromatic compound biosynthetic processGO:00194382170.172
signal transductionGO:00071654550.162
enzyme linked receptor protein signaling pathwayGO:00071671060.161
transcription dna templatedGO:00063511810.157
programmed cell deathGO:00125011190.155
embryonic skeletal system developmentGO:0048706970.155
maintenance of locationGO:005123540.154
chordate embryonic developmentGO:00430092710.153
negative regulation of axon extension involved in axon guidanceGO:004884310.147
regulation of nucleic acid templated transcriptionGO:19035062130.141
regulation of rna metabolic processGO:00512522240.139
cellular nitrogen compound metabolic processGO:00346412900.132
regulation of nitrogen compound metabolic processGO:00511712510.132
positive regulation of biological processGO:00485182530.130
generation of neuronsGO:00486993850.125
cell surface receptor signaling pathwayGO:00071663250.123
organic cyclic compound biosynthetic processGO:19013622230.121
macromolecule biosynthetic processGO:00090592270.119
developmental growth involved in morphogenesisGO:0060560860.119
cellular ketone metabolic processGO:0042180110.118
regulation of rna biosynthetic processGO:20011412130.115
regionalizationGO:00030022740.115
eye developmentGO:00016542770.110
regulation of biological qualityGO:00650082630.108
negative regulation of axon guidanceGO:190266810.107
positive regulation of cellular processGO:00485222010.107
cranial ganglion developmentGO:006155030.107
protein metabolic processGO:00195381830.106
organic acid metabolic processGO:0006082310.104
regulation of multicellular organism growthGO:004001440.104
negative regulation of macromolecule metabolic processGO:0010605760.104
embryonic viscerocranium morphogenesisGO:0048703520.101
carboxylic acid metabolic processGO:0019752220.100
cellular amide metabolic processGO:004360340.100
neuron differentiationGO:00301823530.099
response to chemicalGO:00422213200.099
peptide metabolic processGO:000651810.099
glial cell migrationGO:000834730.096
gene expressionGO:00104672520.095
negative regulation of axon extensionGO:003051770.091
nucleobase containing compound biosynthetic processGO:00346542050.090
regulation of multicellular organismal developmentGO:20000262230.090
multicellular organism growthGO:003526440.089
deathGO:00162651210.089
single organism metabolic processGO:00447102170.087
regulation of macromolecule biosynthetic processGO:00105562250.086
regulation of cell differentiationGO:00455951420.082
cellular aromatic compound metabolic processGO:00067252950.082
response to oxygen containing compoundGO:1901700550.082
regulation of cell deathGO:00109411030.081
regulation of gene expressionGO:00104682650.079
skeletal system morphogenesisGO:00487051020.079
growthGO:00400071740.079
oocyte maturationGO:000155640.079
regulation of anatomical structure morphogenesisGO:00226031300.078
negative regulation of chemotaxisGO:005092240.075
brain developmentGO:00074202930.074
response to corticosteroidGO:003196010.074
macromolecule modificationGO:00434121110.073
negative regulation of multicellular organismal processGO:0051241690.073
negative regulation of protein phosphorylationGO:000193340.072
response to drugGO:004249330.072
olfactory bulb developmentGO:002177240.071
stem cell maintenanceGO:001982740.071
regulation of cell morphogenesis involved in differentiationGO:0010769380.070
response to hormoneGO:0009725480.069
negative regulation of response to stimulusGO:00485851040.069
negative regulation of developmental processGO:0051093650.066
regulation of reproductive processGO:200024140.066
central nervous system neuron developmentGO:0021954290.065
bmp signaling pathwayGO:0030509520.064
response to lipidGO:0033993600.064
regulation of cellular amine metabolic processGO:003323800.064
response to stressGO:00069502630.064
inner ear developmentGO:00488391260.063
cellular component assemblyGO:00226071700.063
muscle cell developmentGO:00550011150.063
embryonic skeletal joint morphogenesisGO:006027230.062
somite developmentGO:0061053960.062
cell deathGO:00082191210.061
regulation of developmental processGO:00507932470.061
nucleobase containing compound metabolic processGO:00061392740.061
negative regulation of neuron projection developmentGO:001097790.061
cellular response to organic substanceGO:00713101050.060
organic cyclic compound metabolic processGO:19013603010.060
olfactory lobe developmentGO:002198840.060
small molecule metabolic processGO:0044281770.059
sensory organ developmentGO:00074233930.059
cellular component morphogenesisGO:00329893360.057
heart processGO:0003015710.057
cell part morphogenesisGO:00329902460.057
urogenital system developmentGO:0001655970.057
cellular nitrogen compound biosynthetic processGO:00442712180.057
nucleic acid templated transcriptionGO:00976591810.056
cell morphogenesis involved in neuron differentiationGO:00486671630.055
negative regulation of metabolic processGO:0009892860.055
positive regulation of transportGO:005105020.055
regulation of cellular ketone metabolic processGO:001056570.054
cranial nerve developmentGO:0021545420.054
heterocycle metabolic processGO:00464832900.053
negative regulation of signalingGO:0023057960.053
cellular protein metabolic processGO:00442671290.053
negative regulation of cellular metabolic processGO:0031324770.052
multi organism processGO:00517041340.052
muscle structure developmentGO:00610611960.051
regulation of biosynthetic processGO:00098892500.051
amine metabolic processGO:000930820.051
meiotic nuclear divisionGO:000712640.050
regulation of epithelial cell proliferationGO:005067830.050
larval developmentGO:000216420.049
branchiomotor neuron axon guidanceGO:002178510.049
specification of symmetryGO:00097992040.049
axon developmentGO:00615641660.049
cell growthGO:0016049570.048
cellular response to chemical stimulusGO:00708871570.048
regulation of apoptotic processGO:0042981980.048
cellular amine metabolic processGO:004410620.047
response to external stimulusGO:00096052640.047
regulation of protein metabolic processGO:0051246560.046
agingGO:000756820.046
neuron projection extensionGO:1990138450.046
negative regulation of cell projection organizationGO:003134590.045
organonitrogen compound metabolic processGO:1901564740.045
head developmentGO:00603223030.045
cell projection organizationGO:00300302840.045
otic vesicle morphogenesisGO:0071600340.044
hormone secretionGO:004687920.044
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.044
negative regulation of protein kinase activityGO:000646940.044
muscle cell differentiationGO:00426921390.044
embryonic heart tube morphogenesisGO:00031431080.043
cellular amino acid metabolic processGO:000652070.043
cellular macromolecule biosynthetic processGO:00346452240.043
negative regulation of protein metabolic processGO:0051248160.043
negative regulation of axonogenesisGO:005077170.043
multicellular organismal response to stressGO:003355520.043
regulation of cell shapeGO:000836010.042
negative regulation of nitrogen compound metabolic processGO:0051172590.042
system processGO:00030081850.041
embryo development ending in birth or egg hatchingGO:00097922710.041
circulatory system processGO:0003013870.041
chemotaxisGO:00069351040.041
transcription from rna polymerase ii promoterGO:0006366800.040
positive regulation of signalingGO:0023056560.040
cellular response to external stimulusGO:007149620.040
negative regulation of nucleobase containing compound metabolic processGO:0045934590.039
cellular protein modification processGO:00064641000.039
negative regulation of protein serine threonine kinase activityGO:007190120.039
camera type eye developmentGO:00430102220.039
single organism organelle organizationGO:19025891990.039
regulation of programmed cell deathGO:00430671010.039
negative regulation of cell communicationGO:0010648960.039
negative regulation of gliogenesisGO:001401410.038
regulation of cell growthGO:0001558290.038
determination of bilateral symmetryGO:00098552040.038
regulation of dendrite developmentGO:005077330.038
skeletal system developmentGO:00015011810.038
nucleic acid metabolic processGO:00903042440.038
dorsal ventral pattern formationGO:00099531250.038
hindbrain developmentGO:0030902910.037
blood vessel developmentGO:00015682460.037
response to organic substanceGO:00100331530.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.037
regulation of cellular component organizationGO:0051128860.037
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.037
response to hexoseGO:000974630.036
hemopoiesisGO:00300971830.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.036
positive regulation of cellular catabolic processGO:003133130.035
response to glucocorticoidGO:005138410.035
apoptotic processGO:00069151160.034
skeletal muscle tissue developmentGO:0007519670.034
positive regulation of erk1 and erk2 cascadeGO:007037420.034
regulation of phosphorus metabolic processGO:0051174430.034
negative regulation of macromolecule biosynthetic processGO:0010558480.034
embryonic skeletal joint developmentGO:007249830.034
cell morphogenesisGO:00009022890.033
gland developmentGO:00487321430.033
axon extension involved in axon guidanceGO:0048846100.033
regulation of cytokine productionGO:000181730.032
actin cytoskeleton organizationGO:0030036630.032
transmission of nerve impulseGO:0019226190.032
tube morphogenesisGO:00352393490.032
regulation of metal ion transportGO:001095940.032
embryonic skeletal system morphogenesisGO:0048704930.032
negative regulation of neuron differentiationGO:0045665100.032
nose developmentGO:004358430.032
axon extensionGO:0048675450.032
phosphate containing compound metabolic processGO:00067961080.031
organelle organizationGO:00069962270.031
regulation of cell projection organizationGO:0031344440.031
regulation of cell activationGO:005086510.031
regulation of cellular amino acid metabolic processGO:000652100.031
synaptic target recognitionGO:000803910.031
regulation of multicellular organismal processGO:00512392770.031
axon guidanceGO:0007411860.031
regulation of inflammatory responseGO:005072720.031
regulation of cell morphogenesisGO:0022604420.030
positive regulation of reproductive processGO:200024320.030
otic vesicle developmentGO:0071599420.030
negative regulation of cell morphogenesis involved in differentiationGO:001077180.030
regulation of peptidyl tyrosine phosphorylationGO:005073010.030
positive regulation of catabolic processGO:000989640.030
regulation of cellular biosynthetic processGO:00313262450.030
positive regulation of cellular metabolic processGO:0031325940.030
forebrain cell migrationGO:002188510.030
larval heart developmentGO:000750820.030
cilium morphogenesisGO:0060271850.030
regulation of organelle organizationGO:0033043290.030
negative regulation of bmp signaling pathwayGO:0030514130.029
chemosensory behaviorGO:000763510.029
negative regulation of cell differentiationGO:0045596460.029
blood circulationGO:0008015870.029
cell projection morphogenesisGO:00488582440.029
striated muscle tissue developmentGO:00147061100.029
positive regulation of cellular amine metabolic processGO:003324000.029
response to organic cyclic compoundGO:0014070510.029
cell motilityGO:00488702440.029
facial nerve developmentGO:002156130.029
rna metabolic processGO:00160702190.029
negative regulation of epithelial cell migrationGO:001063310.029
negative regulation of neurogenesisGO:0050768200.029
female sex differentiationGO:004666040.028
vasculature developmentGO:00019442780.028
response to endogenous stimulusGO:0009719830.028
regulation of cell developmentGO:00602841000.028
regulation of neuron migrationGO:200122220.028
positive regulation of macromolecule metabolic processGO:0010604930.027
response to woundingGO:00096111160.027
cellular component biogenesisGO:00440851780.027
sensory organ morphogenesisGO:00905962000.027
regulation of axonogenesisGO:0050770320.027
neurological system processGO:0050877620.027
negative regulation of kinase activityGO:003367340.027
developmental cell growthGO:0048588520.026
regulation of neuron projection developmentGO:0010975400.026
alpha amino acid metabolic processGO:190160530.026
negative chemotaxisGO:005091910.026
nerve developmentGO:0021675450.026
phagocytosisGO:000690930.026
response to vitaminGO:003327330.025
neuron developmentGO:00486662620.025
striated muscle cell differentiationGO:00511461290.025
homeostatic processGO:00425921420.025
positive regulation of cytoskeleton organizationGO:005149530.025
macromolecular complex subunit organizationGO:0043933740.025
reactive oxygen species biosynthetic processGO:190340910.025
small gtpase mediated signal transductionGO:000726480.025
embryonic heart tube developmentGO:00350501330.025
response to steroid hormoneGO:0048545350.025
development of primary female sexual characteristicsGO:004654540.025
cell morphogenesis involved in differentiationGO:00009041950.024
cellular aldehyde metabolic processGO:000608140.024
response to estrogenGO:0043627270.024
retinal metabolic processGO:004257430.024
secondary metabolic processGO:001974830.024
regulation of transmembrane transporter activityGO:002289820.024
regulation of heart contractionGO:0008016320.024
otic vesicle formationGO:0030916270.024
negative regulation of gene expressionGO:0010629650.024
digestive tract morphogenesisGO:00485462310.024
ovulation cycleGO:004269820.024
kidney developmentGO:0001822920.024
response to nutrientGO:000758430.024
positive regulation of multicellular organismal processGO:0051240520.023
cellular response to nutrient levelsGO:003166920.023
epithelial tube morphogenesisGO:00605621480.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
regulation of synapse assemblyGO:005196330.023
regulation of intracellular signal transductionGO:1902531570.023
regulation of response to cytokine stimulusGO:006075930.023
cellular response to radiationGO:007147840.023
protein modification processGO:00362111000.023
bone morphogenesisGO:0060349110.022
regulation of skeletal muscle tissue developmentGO:004864140.022
negative regulation of rna biosynthetic processGO:1902679450.022
otic placode formationGO:0043049230.022
developmental growthGO:00485891660.022
phosphorylationGO:0016310690.022
negative regulation of cell developmentGO:0010721260.022
renal tubule morphogenesisGO:006133310.022
response to carbohydrateGO:000974330.022
response to monosaccharideGO:003428430.022
regulation of cellular component movementGO:0051270550.021
inner ear morphogenesisGO:0042472630.021
regulation of endothelial cell proliferationGO:000193610.021
action potentialGO:0001508190.021
negative regulation of rna metabolic processGO:0051253480.021
branching morphogenesis of a nerveGO:004875540.021
segmentationGO:0035282970.021
regulation of dendrite morphogenesisGO:004881430.021
negative regulation of signal transductionGO:0009968940.021
taxisGO:00423301090.021
ectodermal placode formationGO:0060788260.021
negative regulation of neuron projection regenerationGO:007057140.021
specification of organ axis polarityGO:001008420.021
intracellular signal transductionGO:0035556850.021
striated muscle cell developmentGO:00550021080.021
adrenergic receptor signaling pathwayGO:007187550.021
central nervous system projection neuron axonogenesisGO:0021952150.020
negative regulation of nucleic acid templated transcriptionGO:1903507450.020
retina development in camera type eyeGO:00600411460.020
rhombomere developmentGO:0021546190.020
regulation of calcium ion transportGO:005192420.020
heart contractionGO:0060047710.020
protein localization to nucleusGO:003450430.020
negative regulation of biosynthetic processGO:0009890550.020
regulation of neurogenesisGO:0050767870.020
immune system processGO:00023762410.020
skin developmentGO:0043588540.020
cellular response to hormone stimulusGO:0032870390.020
blood vessel morphogenesisGO:00485142160.020
positive regulation of metabolic processGO:00098931080.020
primary neural tube formationGO:001402010.019
regulation of protein catabolic processGO:004217610.019
cellular component assembly involved in morphogenesisGO:00109271070.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
anterior posterior pattern specificationGO:00099521520.019
regulation of mrna splicing via spliceosomeGO:004802430.019
post embryonic organ developmentGO:004856940.019
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.019
regulation of erk1 and erk2 cascadeGO:007037240.019
neuron recognitionGO:0008038180.019
response to external biotic stimulusGO:0043207970.019
neural crest cell differentiationGO:0014033720.019
regulation of cell proliferationGO:0042127370.018
protein polymerizationGO:005125840.018
cell adhesion mediated by integrinGO:003362710.018
cell proliferationGO:0008283800.018
regulation of response to stressGO:0080134360.018
positive regulation of cell adhesionGO:004578510.018
regulation of localizationGO:00328791040.018
stem cell proliferationGO:007208940.018
carbohydrate biosynthetic processGO:001605110.018
cellular hormone metabolic processGO:0034754190.018
regulation of synapse organizationGO:005080730.018
proteasomal protein catabolic processGO:001049820.018
morphogenesis of a branching structureGO:0001763210.018
cell recognitionGO:0008037190.018
neuron projection extension involved in neuron projection guidanceGO:1902284100.018
mesenchymal cell proliferationGO:001046310.018
cell migration involved in vasculogenesisGO:003544110.018
regulation of cytokine mediated signaling pathwayGO:000195930.018
ectodermal placode morphogenesisGO:0071697320.018
negative regulation of defense responseGO:003134820.018
appendage developmentGO:0048736800.018
cell cell recognitionGO:000998810.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
lens fiber cell morphogenesisGO:007030930.017
multi organism cellular processGO:004476420.017
positive regulation of cellular component biogenesisGO:004408930.017
alternative mrna splicing via spliceosomeGO:000038010.017
regulation of cytoplasmic transportGO:190364940.017
regulation of myotube differentiationGO:001083020.017
negative regulation of mapk cascadeGO:004340940.017
renal system developmentGO:0072001940.017
tube closureGO:006060610.017
regulation of stem cell differentiationGO:200073640.017
lens development in camera type eyeGO:0002088220.017
neuron projection developmentGO:00311751800.017
water homeostasisGO:003010440.017
antimicrobial humoral responseGO:001973020.017
response to other organismGO:0051707970.017
response to ketoneGO:190165410.017
negative regulation of cytokine mediated signaling pathwayGO:000196020.017
regulation of rho protein signal transductionGO:003502320.017
positive regulation of response to stimulusGO:0048584800.017
response to biotic stimulusGO:0009607970.016
regulation of membrane potentialGO:0042391230.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
neuronal action potentialGO:0019228180.016
regulation of cellular protein metabolic processGO:0032268520.016
lateral inhibitionGO:004633110.016
actin filament based processGO:0030029640.016
connective tissue developmentGO:0061448990.016
specification of organ positionGO:001015930.016
cytoskeleton organizationGO:0007010960.016
cellular protein catabolic processGO:004425740.016
guanosine containing compound metabolic processGO:190106840.016
morphogenesis of an epithelial foldGO:006057110.016
negative regulation of cellular biosynthetic processGO:0031327550.016
cellular response to estrogen stimulusGO:0071391240.016
sensory perception of painGO:001923310.015
fatty acid transportGO:001590810.015
lens morphogenesis in camera type eyeGO:000208970.015
medial fin developmentGO:0033338160.015
facial nerve morphogenesisGO:002161010.015
skeletal muscle organ developmentGO:0060538780.015
negative regulation of cell deathGO:0060548600.015
neuromuscular synaptic transmissionGO:000727420.015
regulation of response to external stimulusGO:0032101310.015
regulation of gtpase activityGO:004308720.015
glial cell developmentGO:0021782200.015
heart loopingGO:0001947940.015
regulation of mesenchymal cell proliferationGO:001046410.015
thymus developmentGO:0048538100.015
cellular response to organic cyclic compoundGO:0071407380.015
heart developmentGO:00075073130.015
regulation of protein targetingGO:190353320.015
positive regulation of cell cycleGO:004578730.015
ear developmentGO:00435831270.015
positive regulation of immune effector processGO:000269930.015
guanosine containing compound catabolic processGO:190106920.015
erk1 and erk2 cascadeGO:007037140.015
extrinsic apoptotic signaling pathwayGO:009719130.015
single organism reproductive processGO:0044702400.015
negative regulation of cell growthGO:003030870.015
camera type eye morphogenesisGO:00485931080.015
positive regulation of chromatin modificationGO:190331010.015
ectodermal placode developmentGO:0071696370.015
regulation of locomotionGO:0040012550.015
response to glucoseGO:000974930.015
forebrain developmentGO:0030900960.014
gliogenesisGO:0042063450.014
regulation of mrna processingGO:005068430.014
cardiac conductionGO:006133730.014
positive regulation of secretion by cellGO:190353210.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
positive regulation of cell activationGO:005086710.014
membrane invaginationGO:001032410.014
positive regulation of neuron deathGO:190121610.014
mitochondrion organizationGO:000700540.014
negative regulation of developmental growthGO:004864090.014
phosphorus metabolic processGO:00067931090.014
positive regulation of cell deathGO:0010942290.014
establishment of localizationGO:00512342440.014
neural crest cell developmentGO:0014032620.014
positive regulation of protein polymerizationGO:003227320.014
cellular response to endogenous stimulusGO:0071495680.014
pronephros developmentGO:0048793690.014
carbohydrate homeostasisGO:003350010.014
regulation of nucleotide catabolic processGO:003081120.014
negative regulation of synapse assemblyGO:005196420.014
regulation of phosphate metabolic processGO:0019220430.014
regulation of stem cell proliferationGO:007209120.014
actin polymerization or depolymerizationGO:000815420.014
somatic stem cell maintenanceGO:003501910.014
positive regulation of secretionGO:005104710.014
hormone transportGO:000991420.014
response to alkaloidGO:004327920.014
protein localization to plasma membraneGO:007265910.013
regulation of protein localization to nucleusGO:190018020.013
negative regulation of molecular functionGO:0044092230.013
somitogenesisGO:0001756870.013
retina morphogenesis in camera type eyeGO:0060042790.013
neural crest cell migrationGO:0001755420.013
cellular response to starvationGO:000926710.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
trigeminal nerve developmentGO:002155930.013
stem cell differentiationGO:00488631170.013
regulation of bmp signaling pathwayGO:0030510390.013
positive regulation of synapse assemblyGO:005196510.013
negative regulation of growthGO:0045926100.013
reflexGO:006000420.013
positive regulation of mesenchymal cell proliferationGO:000205310.013
convergent extensionGO:00600261180.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.013

smoc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
musculoskeletal system diseaseDOID:1700.052
nervous system diseaseDOID:86300.030
connective tissue diseaseDOID:6500.029
bone diseaseDOID:008000100.023
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
myopathyDOID:42300.017
muscle tissue diseaseDOID:6600.017
muscular diseaseDOID:008000000.017