Danio rerio

0 known processes

sirt5

sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)

(Aliases: zgc:92288)

sirt5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.058
agingGO:000756820.057
lipid catabolic processGO:001604240.057
meiotic nuclear divisionGO:000712640.049
brain developmentGO:00074202930.047
positive regulation of transportGO:005105020.043
central nervous system developmentGO:00074173870.041
positive regulation of cellular component biogenesisGO:004408930.040
proteolysis involved in cellular protein catabolic processGO:005160330.040
positive regulation of secretion by cellGO:190353210.040
cellular macromolecule metabolic processGO:00442603910.039
regulation of biological qualityGO:00650082630.038
amine metabolic processGO:000930820.036
mitochondrion organizationGO:000700540.034
phagocytosisGO:000690930.034
hormone transportGO:000991420.034
positive regulation of cellular catabolic processGO:003133130.033
positive regulation of catabolic processGO:000989640.033
carboxylic acid metabolic processGO:0019752220.033
negative regulation of protein phosphorylationGO:000193340.033
cellular amide metabolic processGO:004360340.032
negative regulation of protein kinase activityGO:000646940.032
response to stressGO:00069502630.031
cellular amine metabolic processGO:004410620.031
regulation of cellular amine metabolic processGO:003323800.031
single organism localizationGO:19025782250.031
regulation of protein complex assemblyGO:004325430.031
hormone secretionGO:004687920.030
organic cyclic compound metabolic processGO:19013603010.030
single organism metabolic processGO:00447102170.030
ubiquitin dependent protein catabolic processGO:000651130.029
maintenance of locationGO:005123540.029
regulation of cellular amino acid metabolic processGO:000652100.029
heterocycle metabolic processGO:00464832900.028
positive regulation of cellular processGO:00485222010.028
regulation of metabolic processGO:00192223590.028
cellular ketone metabolic processGO:0042180110.028
oxoacid metabolic processGO:0043436310.027
regulation of reproductive processGO:200024140.026
negative regulation of cellular processGO:00485232830.026
cellular protein catabolic processGO:004425740.026
multicellular organism growthGO:003526440.026
nucleocytoplasmic transportGO:000691340.025
regulation of nitrogen compound metabolic processGO:00511712510.025
gtp metabolic processGO:004603940.025
cellular amino acid metabolic processGO:000652070.025
regulation of metal ion transportGO:001095940.025
regulation of protein transportGO:005122330.025
organic acid metabolic processGO:0006082310.025
cellular nitrogen compound metabolic processGO:00346412900.025
positive regulation of secretionGO:005104710.025
autophagyGO:000691440.025
cellular response to external stimulusGO:007149620.025
modification dependent protein catabolic processGO:001994130.024
regulation of primary metabolic processGO:00800903110.024
regulation of hormone secretionGO:004688320.024
immune system processGO:00023762410.024
small molecule metabolic processGO:0044281770.024
positive regulation of biological processGO:00485182530.024
regulation of reactive oxygen species metabolic processGO:200037720.024
nuclear transportGO:005116940.024
regulation of purine nucleotide catabolic processGO:003312120.024
regulation of establishment of protein localizationGO:007020140.024
regulation of nucleotide catabolic processGO:003081120.024
rna metabolic processGO:00160702190.023
establishment of protein localization to organelleGO:007259440.023
negative regulation of kinase activityGO:003367340.023
modification dependent macromolecule catabolic processGO:004363230.023
protein polymerizationGO:005125840.023
stem cell proliferationGO:007208940.023
lipid storageGO:001991510.023
cellular aromatic compound metabolic processGO:00067252950.023
cellular response to nutrient levelsGO:003166920.023
regulation of transporter activityGO:003240920.023
proteasomal protein catabolic processGO:001049820.023
establishment of localizationGO:00512342440.022
cellular response to extracellular stimulusGO:003166820.022
gene expressionGO:00104672520.022
signal transductionGO:00071654550.022
cellular component movementGO:00069283350.022
regulation of cellular ketone metabolic processGO:001056570.022
regulation of meiotic cell cycleGO:005144510.021
meiotic cell cycle processGO:190304630.021
single organism transportGO:00447652060.021
positive regulation of cell cycleGO:004578730.021
protein metabolic processGO:00195381830.021
macromolecule biosynthetic processGO:00090592270.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
regulation of synapse organizationGO:005080730.021
organonitrogen compound metabolic processGO:1901564740.021
peptide transportGO:001583310.021
positive regulation of cytokine productionGO:000181920.020
response to chemicalGO:00422213200.020
regulation of cell shapeGO:000836010.020
regulation of cytokine productionGO:000181730.020
regulation of macromolecule biosynthetic processGO:00105562250.020
heterocycle biosynthetic processGO:00181302150.020
organelle organizationGO:00069962270.020
erk1 and erk2 cascadeGO:007037140.020
peptidyl threonine phosphorylationGO:001810710.020
primary neural tube formationGO:001402010.020
regulation of response to stimulusGO:00485832690.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
regulation of nucleoside metabolic processGO:000911820.020
leukocyte proliferationGO:007066110.020
ribonucleoside monophosphate catabolic processGO:000915840.020
guanosine containing compound metabolic processGO:190106840.020
guanosine containing compound catabolic processGO:190106920.020
regulation of cell activationGO:005086510.020
centrosome organizationGO:005129710.020
rna localizationGO:000640340.020
response to uvGO:000941130.020
regulation of epithelial cell proliferationGO:005067830.020
regulation of bindingGO:005109830.019
peptidyl serine phosphorylationGO:001810510.019
response to external stimulusGO:00096052640.019
regulation of oocyte developmentGO:006028130.019
positive regulation of cellular amine metabolic processGO:003324000.019
meiotic chromosome segregationGO:004513230.019
secondary metabolic processGO:001974830.019
protein importGO:001703830.019
positive regulation of map kinase activityGO:004340630.019
centrosome duplicationGO:005129810.019
single organism organelle organizationGO:19025891990.019
cell surface receptor signaling pathwayGO:00071663250.019
adult behaviorGO:003053420.019
regulation of erk1 and erk2 cascadeGO:007037240.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
cellular lipid catabolic processGO:004424230.018
rna modificationGO:000945120.018
neurotransmitter transportGO:000683620.018
gtp catabolic processGO:000618420.018
cellular component morphogenesisGO:00329893360.018
neurotransmitter secretionGO:000726920.018
xenobiotic metabolic processGO:000680540.018
biosynthetic processGO:00090582940.018
cell projection morphogenesisGO:00488582440.018
cognitionGO:005089010.018
regulation of cytoplasmic transportGO:190364940.018
peptide metabolic processGO:000651810.018
hemopoiesisGO:00300971830.018
tissue remodelingGO:004877140.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
regulation of blood pressureGO:000821710.018
nucleic acid metabolic processGO:00903042440.018
phosphorus metabolic processGO:00067931090.017
cytosolic calcium ion transportGO:006040130.017
response to nutrientGO:000758430.017
actin polymerization or depolymerizationGO:000815420.017
regulation of protein catabolic processGO:004217610.017
regulation of rna metabolic processGO:00512522240.017
mononuclear cell proliferationGO:003294310.017
release of sequestered calcium ion into cytosolGO:005120930.017
locomotionGO:00400113130.017
regulation of synapse assemblyGO:005196330.017
regulation of mrna processingGO:005068430.017
cell projection organizationGO:00300302840.017
cellular component biogenesisGO:00440851780.017
centrosome cycleGO:000709810.017
protein import into nucleusGO:000660630.017
regulation of multicellular organism growthGO:004001440.017
regulation of intracellular protein transportGO:003315730.017
protein acetylationGO:000647320.017
nitrogen compound metabolic processGO:00068073190.017
female sex differentiationGO:004666040.017
golgi vesicle transportGO:004819330.017
extrinsic apoptotic signaling pathwayGO:009719130.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
cellular biosynthetic processGO:00442492860.016
negative regulation of protein complex assemblyGO:003133310.016
transcription dna templatedGO:00063511810.016
cell substrate adhesionGO:003158940.016
lipid oxidationGO:003444010.016
immune system developmentGO:00025201910.016
localization of cellGO:00516742440.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
cell motilityGO:00488702440.016
cell morphogenesisGO:00009022890.016
regulation of biosynthetic processGO:00098892500.016
positive regulation of cell activationGO:005086710.016
adherens junction organizationGO:003433240.016
cell part morphogenesisGO:00329902460.016
aromatic compound biosynthetic processGO:00194382170.016
regulation of stem cell proliferationGO:007209120.016
protein localization to nucleusGO:003450430.016
neuron differentiationGO:00301823530.016
negative regulation of mapk cascadeGO:004340940.016
synaptic vesicle transportGO:004848910.016
head developmentGO:00603223030.016
eye developmentGO:00016542770.016
nucleobase containing compound metabolic processGO:00061392740.016
nuclear importGO:005117030.016
internal protein amino acid acetylationGO:000647520.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of systemic arterial blood pressureGO:000307310.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of cell communicationGO:00106462320.016
lymphocyte proliferationGO:004665110.016
response to drugGO:004249330.016
negative regulation of biological processGO:00485193040.016
regulation of tube sizeGO:003515020.016
single organism nuclear importGO:190259330.016
peptidyl lysine acetylationGO:001839420.016
transportGO:00068102200.016
regulation of cellular carbohydrate metabolic processGO:001067540.016
peptidyl serine modificationGO:001820920.016
digestive system developmentGO:00551232890.015
positive regulation of cytoskeleton organizationGO:005149530.015
cellular response to starvationGO:000926710.015
rna transportGO:005065820.015
positive regulation of gtp catabolic processGO:003312610.015
b cell activationGO:004211320.015
tube morphogenesisGO:00352393490.015
positive regulation of cell adhesionGO:004578510.015
nucleoside monophosphate catabolic processGO:000912540.015
organic cyclic compound biosynthetic processGO:19013622230.015
organic substance biosynthetic processGO:19015762890.015
regulation of developmental processGO:00507932470.015
stem cell maintenanceGO:001982740.015
cellular macromolecule biosynthetic processGO:00346452240.015
negative regulation of cellular catabolic processGO:003133030.015
neuroblast proliferationGO:000740520.015
nuclear exportGO:005116810.015
exocytosisGO:000688710.015
regulation of cellular protein catabolic processGO:190336210.015
internal peptidyl lysine acetylationGO:001839320.015
cellular hormone metabolic processGO:0034754190.015
regulation of gtpase activityGO:004308720.015
synaptic growth at neuromuscular junctionGO:005112420.015
homeostatic processGO:00425921420.015
cellular component assemblyGO:00226071700.015
cytokinesisGO:000091030.015
response to carbohydrateGO:000974330.015
atp catabolic processGO:000620040.015
generation of neuronsGO:00486993850.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
regulation of alternative mrna splicing via spliceosomeGO:000038110.015
microtubule organizing center organizationGO:003102310.015
positive regulation of gtpase activityGO:004354710.015
regulation of ion transmembrane transporter activityGO:003241220.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
protein targeting to nucleusGO:004474430.015
system processGO:00030081850.015
estrogen metabolic processGO:000821020.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
positive regulation of nucleoside metabolic processGO:004597910.014
nucleobase containing compound transportGO:001593120.014
compound eye developmentGO:004874920.014
regulation of sequestering of calcium ionGO:005128240.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
regulation of protein localization to nucleusGO:190018020.014
ion transportGO:00068111140.014
regulation of transmembrane transporter activityGO:002289820.014
regulation of cellular biosynthetic processGO:00313262450.014
purine nucleoside monophosphate catabolic processGO:000912840.014
regulation of protein targetingGO:190353320.014
cell matrix adhesionGO:000716040.014
nucleic acid transportGO:005065720.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
establishment of rna localizationGO:005123630.014
protein homooligomerizationGO:005126030.014
cellular component disassemblyGO:002241110.014
regulation of macromolecule metabolic processGO:00602553170.014
muscle structure developmentGO:00610611960.014
regulation of nucleocytoplasmic transportGO:004682220.014
response to abiotic stimulusGO:00096281220.014
regulation of cellular metabolic processGO:00313233200.014
negative regulation of catabolic processGO:000989530.014
regulation of multicellular organismal developmentGO:20000262230.014
toll like receptor signaling pathwayGO:000222440.014
regulation of autophagyGO:001050630.014
establishment of synaptic vesicle localizationGO:009748010.014
regulation of gtp catabolic processGO:003312420.014
alpha amino acid metabolic processGO:190160530.014
regulation of gene expressionGO:00104682650.014
membrane fusionGO:006102520.014
regulation of calcium ion transportGO:005192420.014
rna biosynthetic processGO:00327741810.013
activation of mapk activityGO:000018730.013
synaptic vesicle localizationGO:009747910.013
chordate embryonic developmentGO:00430092710.013
regulation of neural precursor cell proliferationGO:200017730.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
membrane invaginationGO:001032410.013
macromolecule modificationGO:00434121110.013
regulation of stem cell differentiationGO:200073640.013
regulation of carbohydrate metabolic processGO:000610940.013
protein polyubiquitinationGO:000020940.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
deathGO:00162651210.013
cell migrationGO:00164772370.013
endocrine hormone secretionGO:006098620.013
neuron neuron synaptic transmissionGO:000727010.013
carboxylic acid catabolic processGO:004639530.013
regulation of endothelial cell proliferationGO:000193610.013
cell proliferationGO:0008283800.013
mitotic dna integrity checkpointGO:004477440.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
peptidyl threonine modificationGO:001821010.013
regulation of neurotransmitter transportGO:005158810.013
neuron developmentGO:00486662620.013
cellular protein metabolic processGO:00442671290.013
cation transportGO:0006812810.013
sequestering of calcium ionGO:005120830.013
multicellular organismal metabolic processGO:004423620.013
dna templated transcription elongationGO:000635430.013
response to corticosteroidGO:003196010.013
regulation of cellular component organizationGO:0051128860.013
regulation of protein ubiquitinationGO:003139630.013
apoptotic process involved in developmentGO:190274220.013
cellular response to radiationGO:007147840.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of dna templated transcription elongationGO:003278430.013
regulation of signal transductionGO:00099662250.013
mitochondrial transportGO:000683920.013
negative regulation of stem cell differentiationGO:200073720.013
odontogenesis of dentin containing toothGO:004247510.013
establishment of protein localization to plasma membraneGO:009000210.013
regulation of protein import into nucleusGO:004230620.013
response to vitaminGO:003327330.013
negative regulation of map kinase activityGO:004340720.013
protein heterooligomerizationGO:005129110.013
cellular response to decreased oxygen levelsGO:003629410.013
regulation of transcription dna templatedGO:00063552130.012
regulation of neurotransmitter secretionGO:004692810.012
pyruvate metabolic processGO:000609010.012
cellular response to light stimulusGO:007148240.012
positive regulation of immune effector processGO:000269930.012
response to glucoseGO:000974930.012
germ line stem cell maintenanceGO:003071820.012
positive regulation of protein complex assemblyGO:003133420.012
negative regulation of sequestering of calcium ionGO:005128340.012
regulation of dendrite developmentGO:005077330.012
sensory perception of painGO:001923310.012
response to monosaccharideGO:003428430.012
neuromuscular synaptic transmissionGO:000727420.012
regulation of multicellular organismal processGO:00512392770.012
sequestering of metal ionGO:005123830.012
regulation of signalingGO:00230512350.012
protein secretionGO:000930610.012
regulation of localizationGO:00328791040.012
embryo development ending in birth or egg hatchingGO:00097922710.012
regulation of blood vessel sizeGO:005088020.012
negative regulation of cytokine productionGO:000181810.012
regulation of jak stat cascadeGO:004642530.012
ameboidal type cell migrationGO:00016671430.012
developmental programmed cell deathGO:001062340.012
protein acylationGO:004354330.012
pole plasm assemblyGO:000731540.012
response to alkaloidGO:004327920.012
somatic muscle developmentGO:000752540.012
phagocytosis engulfmentGO:000691110.012
regulation of rho protein signal transductionGO:003502320.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
regulation of cell substrate adhesionGO:001081010.012
cell cycle g1 s phase transitionGO:004484310.012
cellular transition metal ion homeostasisGO:004691630.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
nucleic acid templated transcriptionGO:00976591810.012
digestive tract morphogenesisGO:00485462310.012
positive regulation of macromolecule metabolic processGO:0010604930.012
carbohydrate homeostasisGO:003350010.012
cellular protein modification processGO:00064641000.012
organic substance transportGO:0071702580.012
regulation of hematopoietic progenitor cell differentiationGO:190153210.012
morphogenesis of an epitheliumGO:00020093330.012
cell cycle arrestGO:000705010.012
fatty acid oxidationGO:001939510.012
regulation of chromosome segregationGO:005198310.012
rna 3 end processingGO:003112320.012
g2 m transition of mitotic cell cycleGO:000008640.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
negative regulation of defense responseGO:003134820.011
cellular response to organic substanceGO:00713101050.011
regulation of cell matrix adhesionGO:000195210.011
peptidyl lysine methylationGO:001802230.011
negative regulation of nuclear divisionGO:005178430.011
positive regulation of dna metabolic processGO:005105410.011
convergent extensionGO:00600261180.011
lateral inhibitionGO:004633110.011
positive regulation of neuron apoptotic processGO:004352510.011
development of primary female sexual characteristicsGO:004654540.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
regulation of wound healingGO:006104120.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
positive regulation of stem cell proliferationGO:200064810.011
locomotor rhythmGO:004547530.011
ion transmembrane transportGO:0034220910.011
mesenchymal cell proliferationGO:001046310.011
tube closureGO:006060610.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
regulation of lipid transportGO:003236840.011
vasculature developmentGO:00019442780.011
regulation of response to cytokine stimulusGO:006075930.011
cellular response to biotic stimulusGO:007121630.011
regulation of inflammatory responseGO:005072720.011
glycoprotein metabolic processGO:0009100230.011
alcohol biosynthetic processGO:004616520.011
negative regulation of intracellular transportGO:003238730.011
dicarboxylic acid transportGO:000683510.011
regulation of synaptic plasticityGO:004816710.011
response to organic substanceGO:00100331530.011
actin filament based processGO:0030029640.011
response to hexoseGO:000974630.011
oocyte maturationGO:000155640.011
stem cell divisionGO:001714510.011
protein dephosphorylationGO:000647030.011
response to topologically incorrect proteinGO:003596620.011
production of molecular mediator of immune responseGO:000244020.011
positive regulation of cell divisionGO:005178120.011
positive regulation of epithelial cell proliferationGO:005067910.011
protein localization to plasma membraneGO:007265910.011
actin filament polymerizationGO:003004120.011
regulation of cell deathGO:00109411030.011
monocarboxylic acid catabolic processGO:007232930.011
b cell differentiationGO:003018310.011
regulation of protein polymerizationGO:003227120.011
mrna transportGO:005102820.011
regulation of response to biotic stimulusGO:000283120.011
protein modification processGO:00362111000.011
nitrogen compound transportGO:0071705230.011
cellular respirationGO:004533330.011
spermatid developmentGO:000728620.011
cell deathGO:00082191210.011
heart developmentGO:00075073130.010
transmembrane transportGO:00550851200.010
cofactor metabolic processGO:0051186150.010
endosomal transportGO:001619720.010
positive regulation of synapse assemblyGO:005196510.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
intracellular signal transductionGO:0035556850.010
macromolecular complex disassemblyGO:003298410.010
organelle fusionGO:004828430.010
protein stabilizationGO:005082120.010
digestive tract developmentGO:00485652650.010
female meiotic divisionGO:000714320.010
medulla oblongata developmentGO:002155040.010
regulation of mitochondrion organizationGO:001082110.010
somatic stem cell maintenanceGO:003501910.010
cellular modified amino acid metabolic processGO:000657530.010
programmed cell deathGO:00125011190.010
positive regulation of leukocyte mediated immunityGO:000270510.010
oxidation reduction processGO:0055114410.010
liver developmentGO:0001889960.010
g2 dna damage checkpointGO:003157230.010
cytoskeleton dependent cytokinesisGO:006164030.010
mitotic dna damage checkpointGO:004477340.010
organic acid catabolic processGO:001605430.010
negative regulation of intracellular protein transportGO:009031730.010
mitotic cytokinesisGO:000028130.010
signal transduction in absence of ligandGO:003803410.010
negative regulation of metabolic processGO:0009892860.010
cilium morphogenesisGO:0060271850.010
regulation of organ growthGO:004662030.010
multicellular organismal response to stressGO:003355520.010
protein complex disassemblyGO:004324110.010
glucose homeostasisGO:004259310.010
histone deacetylationGO:001657520.010
i kappab kinase nf kappab signalingGO:000724940.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.010
blood vessel developmentGO:00015682460.010
renal tubule morphogenesisGO:006133310.010
viral processGO:001603210.010
inositol lipid mediated signalingGO:004801720.010
positive regulation of stress activated mapk cascadeGO:003287430.010
branching morphogenesis of a nerveGO:004875540.010
negative regulation of dna metabolic processGO:005105340.010

sirt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.032
disease of metabolismDOID:001466700.032
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.017
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
immune system diseaseDOID:291400.012
nervous system diseaseDOID:86300.012
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011