Danio rerio

0 known processes

ptges3a

prostaglandin E synthase 3a (cytosolic)

(Aliases: cPGES-1,zgc:77131,ptges3,Tebp,zgc:65804,wu:fb98d06)

ptges3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of metabolic processGO:00192223590.504
Rat
regulation of biological qualityGO:00650082630.196
macromolecule biosynthetic processGO:00090592270.192
Human Mouse
regulation of gene expressionGO:00104682650.185
Rat
mitochondrion organizationGO:000700540.176
anterior posterior pattern specificationGO:00099521520.158
regulation of cellular metabolic processGO:00313233200.150
purine nucleoside monophosphate catabolic processGO:000912840.143
signal transductionGO:00071654550.143
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.132
agingGO:000756820.132
regulation of rna biosynthetic processGO:20011412130.128
nucleic acid templated transcriptionGO:00976591810.120
locomotionGO:00400113130.116
regulation of protein modification by small protein conjugation or removalGO:190332030.105
organic cyclic compound metabolic processGO:19013603010.103
Human
regulation of nitrogen compound metabolic processGO:00511712510.097
purine ribonucleoside monophosphate catabolic processGO:000916940.097
regulation of macromolecule metabolic processGO:00602553170.096
Rat
regulation of cellular macromolecule biosynthetic processGO:20001122220.093
positive regulation of biological processGO:00485182530.091
Rat
positive regulation of cellular processGO:00485222010.088
segmentationGO:0035282970.088
cellular protein metabolic processGO:00442671290.079
Human
negative regulation of cellular processGO:00485232830.077
Rat
digestive tract morphogenesisGO:00485462310.077
larval developmentGO:000216420.075
regulation of response to stimulusGO:00485832690.075
regulation of protein ubiquitinationGO:003139630.074
ribonucleoside monophosphate catabolic processGO:000915840.074
vasculature developmentGO:00019442780.072
organic cyclic compound biosynthetic processGO:19013622230.071
Human
nucleoside monophosphate catabolic processGO:000912540.071
gene expressionGO:00104672520.070
Rat
regulation of signal transductionGO:00099662250.069
regulation of transcription from rna polymerase ii promoterGO:00063571140.068
aromatic compound biosynthetic processGO:00194382170.067
Human
regulation of rna metabolic processGO:00512522240.065
modification dependent macromolecule catabolic processGO:004363230.065
organic substance biosynthetic processGO:19015762890.063
Human Mouse Rat
cellular macromolecule metabolic processGO:00442603910.063
Human Mouse
regulation of biosynthetic processGO:00098892500.062
single organism localizationGO:19025782250.062
negative regulation of biological processGO:00485193040.062
Rat
single organism metabolic processGO:00447102170.062
Human Mouse Rat
single organism biosynthetic processGO:0044711710.061
Human Mouse Rat
transcription dna templatedGO:00063511810.061
cellular amide metabolic processGO:004360340.060
nucleobase containing compound biosynthetic processGO:00346542050.059
Human
organic acid metabolic processGO:0006082310.059
Human Mouse Rat
central nervous system developmentGO:00074173870.058
embryo development ending in birth or egg hatchingGO:00097922710.058
Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.057
regulation of cellular amine metabolic processGO:003323800.056
heterocycle biosynthetic processGO:00181302150.056
Human
cellular nitrogen compound metabolic processGO:00346412900.054
Human
nucleic acid metabolic processGO:00903042440.052
Human
nitrogen compound metabolic processGO:00068073190.052
Human
small molecule metabolic processGO:0044281770.051
Human Mouse Rat
immune system processGO:00023762410.051
regulation of cellular biosynthetic processGO:00313262450.050
atp catabolic processGO:000620040.049
oocyte maturationGO:000155640.049
cell surface receptor signaling pathwayGO:00071663250.049
nucleobase containing compound metabolic processGO:00061392740.048
Human
regulation of signalingGO:00230512350.048
regulation of protein complex assemblyGO:004325430.047
hemopoiesisGO:00300971830.047
dicarboxylic acid metabolic processGO:004364810.046
regulation of cell communicationGO:00106462320.045
generation of neuronsGO:00486993850.045
regionalizationGO:00030022740.044
cellular nitrogen compound biosynthetic processGO:00442712180.044
Human
regulation of calcium ion transportGO:005192420.044
cellular response to external stimulusGO:007149620.043
blood vessel developmentGO:00015682460.043
positive regulation of cellular component biogenesisGO:004408930.042
positive regulation of catabolic processGO:000989640.042
response to external stimulusGO:00096052640.042
microtubule cytoskeleton organizationGO:0000226330.042
localization of cellGO:00516742440.042
antimicrobial humoral responseGO:001973020.040
cellular component biogenesisGO:00440851780.039
cellular component assemblyGO:00226071700.039
single organism organelle organizationGO:19025891990.039
cytoskeleton organizationGO:0007010960.038
regulation of primary metabolic processGO:00800903110.038
positive regulation of nitrogen compound metabolic processGO:0051173690.037
regulation of nucleotide catabolic processGO:003081120.037
regulation of transcription dna templatedGO:00063552130.037
chordate embryonic developmentGO:00430092710.037
cellular protein modification processGO:00064641000.037
digestive system developmentGO:00551232890.036
cation transportGO:0006812810.036
mitochondrial transportGO:000683920.036
modification dependent protein catabolic processGO:001994130.035
phosphorus metabolic processGO:00067931090.035
centrosome organizationGO:005129710.035
regulation of macromolecule biosynthetic processGO:00105562250.034
regulation of metal ion transportGO:001095940.034
microtubule organizing center organizationGO:003102310.034
protein metabolic processGO:00195381830.034
Human
positive regulation of transportGO:005105020.034
rhombomere 6 developmentGO:002157240.034
peptide metabolic processGO:000651810.034
single organism transportGO:00447652060.034
circadian sleep wake cycleGO:004274520.033
negative regulation of signalingGO:0023057960.033
hematopoietic or lymphoid organ developmentGO:00485341910.032
regulation of erk1 and erk2 cascadeGO:007037240.031
macromolecular complex subunit organizationGO:0043933740.031
negative regulation of protein phosphorylationGO:000193340.031
amine metabolic processGO:000930820.030
establishment of localizationGO:00512342440.030
glucose homeostasisGO:004259310.030
odontogenesis of dentin containing toothGO:004247510.030
intracellular signal transductionGO:0035556850.030
cellular component movementGO:00069283350.029
cellular amine metabolic processGO:004410620.029
response to topologically incorrect proteinGO:003596620.029
organonitrogen compound metabolic processGO:1901564740.029
positive regulation of protein complex assemblyGO:003133420.029
regulation of multicellular organismal processGO:00512392770.029
cilium morphogenesisGO:0060271850.028
morphogenesis of an epitheliumGO:00020093330.028
positive regulation of cellular catabolic processGO:003133130.028
microtubule based processGO:0007017600.028
rna metabolic processGO:00160702190.028
erk1 and erk2 cascadeGO:007037140.027
cellular response to chemical stimulusGO:00708871570.027
transportGO:00068102200.027
regulation of production of molecular mediator of immune responseGO:000270010.027
head developmentGO:00603223030.027
cytoskeleton dependent cytokinesisGO:006164030.027
mononuclear cell proliferationGO:003294310.027
biosynthetic processGO:00090582940.026
Human Mouse Rat
transcription from rna polymerase ii promoterGO:0006366800.026
rostrocaudal neural tube patterningGO:0021903290.026
centrosome cycleGO:000709810.026
ubiquitin dependent protein catabolic processGO:000651130.026
regulation of response to biotic stimulusGO:000283120.026
negative regulation of cellular metabolic processGO:0031324770.025
neurotransmitter transportGO:000683620.025
regulation of reproductive processGO:200024140.025
regulation of cellular carbohydrate metabolic processGO:001067540.025
mitotic dna damage checkpointGO:004477340.025
negative regulation of protein kinase activityGO:000646940.025
regulation of reactive oxygen species metabolic processGO:200037720.025
protein stabilizationGO:005082120.025
heterocycle metabolic processGO:00464832900.025
Human
embryonic pattern specificationGO:0009880440.025
circadian sleep wake cycle sleepGO:005080210.025
negative regulation of response to stimulusGO:00485851040.024
pancreas developmentGO:0031016840.024
regulation of cell activationGO:005086510.024
regulation of sodium ion transportGO:000202820.024
cellular ketone metabolic processGO:0042180110.024
somitogenesisGO:0001756870.023
immune system developmentGO:00025201910.023
behaviorGO:0007610740.023
negative regulation of cell communicationGO:0010648960.023
rna biosynthetic processGO:00327741810.023
regulation of carbohydrate metabolic processGO:000610940.023
regulation of cell shapeGO:000836010.023
regulation of cellular amino acid metabolic processGO:000652100.023
cellular amino acid metabolic processGO:000652070.023
carboxylic acid metabolic processGO:0019752220.023
Human Mouse Rat
purine ribonucleotide metabolic processGO:0009150270.023
regulation of cellular protein catabolic processGO:190336210.023
regulation of cellular ketone metabolic processGO:001056570.023
regulation of localizationGO:00328791040.022
response to organic substanceGO:00100331530.022
regulation of nucleoside metabolic processGO:000911820.022
establishment of protein localization to organelleGO:007259440.022
cell deathGO:00082191210.022
Rat
adult behaviorGO:003053420.022
protein modification processGO:00362111000.022
neural tube patterningGO:0021532330.022
intracellular estrogen receptor signaling pathwayGO:003052030.022
b cell activationGO:004211320.022
regulation of purine nucleotide catabolic processGO:003312120.021
regulation of anatomical structure morphogenesisGO:00226031300.021
cellular response to topologically incorrect proteinGO:003596720.021
carbohydrate homeostasisGO:003350010.021
cell motilityGO:00488702440.021
positive regulation of transcription dna templatedGO:0045893570.021
ion transportGO:00068111140.021
brain developmentGO:00074202930.021
positive regulation of nucleotide catabolic processGO:003081310.021
positive regulation of purine nucleotide catabolic processGO:003312310.021
otolith developmentGO:0048840320.020
tube morphogenesisGO:00352393490.020
negative regulation of signal transductionGO:0009968940.020
amide biosynthetic processGO:004360410.020
regulation of neurotransmitter secretionGO:004692810.020
regulation of microtubule cytoskeleton organizationGO:007050730.020
cellular response to extracellular stimulusGO:003166820.020
protein secretionGO:000930610.020
positive regulation of biosynthetic processGO:0009891680.020
response to light stimulusGO:0009416460.020
regulation of intracellular protein transportGO:003315730.020
epiboly involved in gastrulation with mouth forming secondGO:0055113350.020
autophagyGO:000691440.019
organonitrogen compound biosynthetic processGO:1901566470.019
leukocyte proliferationGO:007066110.019
response to growth factorGO:0070848390.019
peptide transportGO:001583310.019
proteasomal protein catabolic processGO:001049820.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
alpha amino acid metabolic processGO:190160530.019
macromolecule modificationGO:00434121110.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
cellular response to endogenous stimulusGO:0071495680.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
protein polymerizationGO:005125840.018
cell migrationGO:00164772370.018
response to stressGO:00069502630.018
cellular protein catabolic processGO:004425740.018
embryonic organ developmentGO:00485683810.018
regulation of cytoplasmic transportGO:190364940.018
kupffer s vesicle developmentGO:0070121500.018
cellular macromolecule biosynthetic processGO:00346452240.018
Human Mouse
cellular transition metal ion homeostasisGO:004691630.018
negative regulation of protein transportGO:005122430.018
phosphorylationGO:0016310690.018
response to monosaccharideGO:003428430.018
female sex differentiationGO:004666040.018
positive regulation of secretionGO:005104710.017
regulation of nucleocytoplasmic transportGO:004682220.017
positive regulation of metabolic processGO:00098931080.017
Rat
positive regulation of cytoskeleton organizationGO:005149530.017
developmental programmed cell deathGO:001062340.017
positive regulation of response to stimulusGO:0048584800.017
negative regulation of leukocyte differentiationGO:190210610.017
stem cell proliferationGO:007208940.017
calcium mediated signalingGO:001972220.017
respiratory electron transport chainGO:002290420.017
myeloid cell differentiationGO:0030099860.017
erythrocyte differentiationGO:0030218540.017
connective tissue developmentGO:0061448990.017
hormone transportGO:000991420.017
cell part morphogenesisGO:00329902460.017
organelle organizationGO:00069962270.017
negative regulation of kinase activityGO:003367340.017
gastrulationGO:00073692080.017
somite developmentGO:0061053960.017
cellular macromolecular complex assemblyGO:0034622240.017
regulation of stem cell proliferationGO:007209120.017
nuclear importGO:005117030.017
skeletal muscle tissue developmentGO:0007519670.017
cellular response to starvationGO:000926710.017
positive regulation of immune effector processGO:000269930.017
meiosis iGO:000712710.016
single organism nuclear importGO:190259330.016
semicircular canal developmentGO:0060872240.016
cellular response to oxygen levelsGO:007145310.016
transition metal ion transportGO:000004160.016
reactive oxygen species metabolic processGO:007259360.016
cellular response to nutrient levelsGO:003166920.016
erythrocyte homeostasisGO:0034101550.016
leukocyte differentiationGO:0002521250.016
neurological system processGO:0050877620.016
Rat
skeletal muscle organ developmentGO:0060538780.016
cellular biosynthetic processGO:00442492860.016
Human Mouse Rat
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
inner ear developmentGO:00488391260.016
production of molecular mediator of immune responseGO:000244020.016
cellular component morphogenesisGO:00329893360.016
regulation of protein transportGO:005122330.016
fatty acid biosynthetic processGO:000663340.016
Human Mouse Rat
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
convergent extension involved in organogenesisGO:0060029100.016
positive regulation of multi organism processGO:004390230.015
response to endogenous stimulusGO:0009719830.015
b cell differentiationGO:003018310.015
negative regulation of mapk cascadeGO:004340940.015
negative regulation of myeloid cell differentiationGO:004563810.015
regulation of hormone secretionGO:004688320.015
regulation of multicellular organism growthGO:004001440.015
chemosensory behaviorGO:000763510.015
positive regulation of cellular amine metabolic processGO:003324000.015
positive regulation of map kinase activityGO:004340630.015
mitotic dna integrity checkpointGO:004477440.015
ear developmentGO:00435831270.015
astrocyte differentiationGO:004870810.015
blood vessel morphogenesisGO:00485142160.015
hepaticobiliary system developmentGO:0061008980.015
cellular response to growth factor stimulusGO:0071363390.015
g protein coupled receptor signaling pathwayGO:0007186740.015
response to unfolded proteinGO:000698620.015
regulation of hormone levelsGO:0010817210.015
exocrine pancreas developmentGO:0031017280.015
cellular response to light stimulusGO:007148240.014
positive regulation of nucleoside metabolic processGO:004597910.014
cytokinesisGO:000091030.014
regulation of establishment of protein localizationGO:007020140.014
developmental growthGO:00485891660.014
regulation of cellular response to growth factor stimulusGO:0090287350.014
intracellular steroid hormone receptor signaling pathwayGO:003051850.014
Mouse
convergent extensionGO:00600261180.014
mitotic cell cycle processGO:1903047480.014
nucleocytoplasmic transportGO:000691340.014
response to chemicalGO:00422213200.014
androgen metabolic processGO:000820920.014
nuclear transportGO:005116940.014
defense response to fungusGO:005083220.014
regulation of protein metabolic processGO:0051246560.014
lymphocyte proliferationGO:004665110.014
peptidyl serine modificationGO:001820920.014
synaptic growth at neuromuscular junctionGO:005112420.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
olfactory lobe developmentGO:002198840.014
hormone secretionGO:004687920.014
regulation of cytokine productionGO:000181730.014
positive regulation of rna biosynthetic processGO:1902680570.014
protein targeting to nucleusGO:004474430.014
cellular response to radiationGO:007147840.013
cellular response to hypoxiaGO:007145610.013
regulation of developmental processGO:00507932470.013
cell projection morphogenesisGO:00488582440.013
toll like receptor signaling pathwayGO:000222440.013
transmembrane transportGO:00550851200.013
developmental maturationGO:0021700340.013
regulation of circadian sleep wake cycleGO:004274910.013
multi organism processGO:00517041340.013
positive regulation of translationGO:004572710.013
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.013
positive regulation of secretion by cellGO:190353210.013
regulation of tube sizeGO:003515020.013
regulation of molecular functionGO:0065009700.013
positive regulation of cellular metabolic processGO:0031325940.013
regulation of cellular protein metabolic processGO:0032268520.013
circadian sleep wake cycle processGO:002241020.013
positive regulation of defense response to virus by hostGO:000223000.013
macromolecular complex assemblyGO:0065003350.013
cellular component assembly involved in morphogenesisGO:00109271070.013
regulation of tissue remodelingGO:003410320.013
reactive oxygen species biosynthetic processGO:190340910.012
cell projection organizationGO:00300302840.012
regulation of carbohydrate biosynthetic processGO:004325510.012
midbrain hindbrain boundary developmentGO:0030917230.012
meiotic nuclear divisionGO:000712640.012
eye developmentGO:00016542770.012
negative regulation of metabolic processGO:0009892860.012
cellular response to unfolded proteinGO:003462020.012
cell cycleGO:0007049930.012
mitotic cytokinesisGO:000028130.012
cellular response to decreased oxygen levelsGO:003629410.012
response to hexoseGO:000974630.012
cell morphogenesisGO:00009022890.012
regulation of cell substrate adhesionGO:001081010.012
actin polymerization or depolymerizationGO:000815420.012
neuron developmentGO:00486662620.012
mrna stabilizationGO:004825540.012
phosphate containing compound metabolic processGO:00067961080.012
intracellular receptor signaling pathwayGO:0030522300.012
Mouse
response to fungusGO:0009620250.012
specification of axis polarityGO:006500140.012
positive regulation of muscle organ developmentGO:004863610.012
tissue remodelingGO:004877140.012
maintenance of locationGO:005123540.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
negative regulation of protein import into nucleusGO:004230820.012
lateral line developmentGO:0048882660.012
positive regulation of gene expressionGO:0010628710.011
Rat
regulation of behaviorGO:0050795240.011
regulation of protein targetingGO:190353320.011
protein importGO:001703830.011
hormone biosynthetic processGO:004244630.011
homeostatic processGO:00425921420.011
negative regulation of macromolecule metabolic processGO:0010605760.011
mitochondrion morphogenesisGO:007058420.011
apoptotic process involved in morphogenesisGO:006056120.011
camera type eye developmentGO:00430102220.011
regulation of blood vessel sizeGO:005088020.011
divalent inorganic cation transportGO:0072511210.011
camera type eye morphogenesisGO:00485931080.011
ribonucleotide metabolic processGO:0009259270.011
pronuclear migrationGO:003504610.011
er nucleus signaling pathwayGO:000698420.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
regulation of protein catabolic processGO:004217610.011
response to uvGO:000941130.011
ovulation cycleGO:004269820.011
organic substance transportGO:0071702580.011
reproductive processGO:0022414400.011
developmental growth involved in morphogenesisGO:0060560860.011
sphingolipid biosynthetic processGO:003014820.011
organelle assemblyGO:00709251100.011
response to alkaloidGO:004327920.011
regulation of response to extracellular stimulusGO:003210410.011
protein complex biogenesisGO:0070271300.011
regulation of skeletal muscle tissue developmentGO:004864140.010
mesenchymal cell proliferationGO:001046310.010
telomere organizationGO:003220010.010
regulation of bone remodelingGO:004685020.010
detection of external stimulusGO:0009581240.010
regulation of protein import into nucleusGO:004230620.010
negative regulation of i kappab kinase nf kappab signalingGO:004312410.010
cell migration involved in heart formationGO:0060974100.010
nucleotide biosynthetic processGO:0009165210.010
hindbrain developmentGO:0030902910.010
small molecule catabolic processGO:004428230.010
metal ion transportGO:0030001580.010
sensory organ morphogenesisGO:00905962000.010
actin filament polymerizationGO:003004120.010
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.010
angiogenesisGO:00015251580.010
response to abiotic stimulusGO:00096281220.010
lipid metabolic processGO:0006629520.010
Human Mouse Rat
regulation of protein localization to nucleusGO:190018020.010
digestive tract developmentGO:00485652650.010

ptges3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.028
inherited metabolic disorderDOID:65500.023
disease of anatomical entityDOID:700.019
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.013
disease of cellular proliferationDOID:1456600.011
cardiovascular system diseaseDOID:128700.010
heart diseaseDOID:11400.010