Danio rerio

30 known processes

ier2

immediate early response 2

(Aliases: wu:fb01b03,fb01b03)

ier2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heart developmentGO:00075073130.504
digestive system developmentGO:00551232890.462
digestive tract morphogenesisGO:00485462310.435
tube morphogenesisGO:00352393490.382
determination of left right symmetryGO:00073681790.301
morphogenesis of an epitheliumGO:00020093330.296
regulation of developmental processGO:00507932470.295
notochord developmentGO:0030903540.259
gastrulationGO:00073692080.254
determination of bilateral symmetryGO:00098552040.254
enzyme linked receptor protein signaling pathwayGO:00071671060.217
embryonic organ developmentGO:00485683810.215
cell migration involved in gastrulationGO:0042074790.185
specification of symmetryGO:00097992040.172
larval developmentGO:000216420.170
regulation of multicellular organism growthGO:004001440.163
regionalizationGO:00030022740.161
urogenital system developmentGO:0001655970.156
dorsal ventral pattern formationGO:00099531250.154
signal transductionGO:00071654550.152
digestive tract developmentGO:00485652650.151
hepaticobiliary system developmentGO:0061008980.150
muscle tissue developmentGO:00605371100.149
endoderm developmentGO:0007492490.149
regulation of gene expressionGO:00104682650.144
stem cell divisionGO:001714510.132
nucleocytoplasmic transportGO:000691340.127
mesoderm developmentGO:0007498880.126
neuroblast proliferationGO:000740520.113
cilium morphogenesisGO:0060271850.111
angiogenesisGO:00015251580.106
embryonic heart tube developmentGO:00350501330.106
multicellular organism growthGO:003526440.103
cellular component movementGO:00069283350.102
ameboidal type cell migrationGO:00016671430.101
regulation of signal transductionGO:00099662250.101
formation of primary germ layerGO:0001704620.097
nuclear transportGO:005116940.090
kupffer s vesicle developmentGO:0070121500.089
tube closureGO:006060610.085
localization of cellGO:00516742440.085
regulation of multicellular organismal processGO:00512392770.077
regulation of protein targetingGO:190353320.075
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.074
regulation of protein import into nucleusGO:004230620.074
liver developmentGO:0001889960.073
regulation of signalingGO:00230512350.073
regulation of multicellular organismal developmentGO:20000262230.072
protein localization to nucleusGO:003450430.072
neuron differentiationGO:00301823530.071
regulation of nucleocytoplasmic transportGO:004682220.069
epithelial tube morphogenesisGO:00605621480.067
vasculature developmentGO:00019442780.063
response to chemicalGO:00422213200.062
organelle organizationGO:00069962270.062
sensory perception of chemical stimulusGO:000760630.061
locomotionGO:00400113130.061
nucleic acid metabolic processGO:00903042440.061
negative regulation of signal transductionGO:0009968940.060
protein import into nucleusGO:000660630.060
positive regulation of nitrogen compound metabolic processGO:0051173690.060
cell recognitionGO:0008037190.060
defense response to other organismGO:0098542330.059
regulation of response to stimulusGO:00485832690.059
neuron recognitionGO:0008038180.058
cartilage developmentGO:0051216960.057
cell fate commitment involved in formation of primary germ layerGO:0060795260.057
regulation of nucleobase containing compound metabolic processGO:00192192500.057
negative regulation of cell communicationGO:0010648960.057
heart joggingGO:0003146400.056
somite developmentGO:0061053960.056
mesodermal cell differentiationGO:0048333210.056
nitrogen compound metabolic processGO:00068073190.056
mesoderm morphogenesisGO:0048332510.055
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.055
blood vessel morphogenesisGO:00485142160.055
protein importGO:001703830.054
extrinsic apoptotic signaling pathwayGO:009719130.054
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.053
regulation of macromolecule metabolic processGO:00602553170.053
regulation of metabolic processGO:00192223590.052
gland developmentGO:00487321430.052
regulation of cytoplasmic transportGO:190364940.052
organic cyclic compound metabolic processGO:19013603010.052
regulation of primary metabolic processGO:00800903110.052
regulation of macromolecule biosynthetic processGO:00105562250.051
heart morphogenesisGO:00030071560.051
cell cell signaling involved in cell fate commitmentGO:0045168120.050
regulation of cell deathGO:00109411030.050
heart loopingGO:0001947940.050
macromolecular complex subunit organizationGO:0043933740.048
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.048
otic vesicle morphogenesisGO:0071600340.048
regulation of transcription from rna polymerase ii promoterGO:00063571140.047
cilium organizationGO:0044782710.045
optic placode formationGO:000174340.045
sequestering of metal ionGO:005123830.045
cell migrationGO:00164772370.045
regulation of cellular amine metabolic processGO:003323800.045
cell projection organizationGO:00300302840.045
regulation of axonogenesisGO:0050770320.044
apoptotic processGO:00069151160.044
regulation of bmp signaling pathwayGO:0030510390.044
bmp signaling pathwayGO:0030509520.044
gene expressionGO:00104672520.043
response to stressGO:00069502630.043
negative regulation of cellular processGO:00485232830.043
regulation of protein transportGO:005122330.041
cellular response to endogenous stimulusGO:0071495680.041
cilium assemblyGO:0042384580.041
regulation of cellular component movementGO:0051270550.041
optic placode formation involved in camera type eye formationGO:004661930.040
negative regulation of protein phosphorylationGO:000193340.040
single organism nuclear importGO:190259330.040
determination of heart left right asymmetryGO:00613711170.040
chordate embryonic developmentGO:00430092710.040
organelle localizationGO:0051640490.040
epibolyGO:0090504410.039
embryonic heart tube morphogenesisGO:00031431080.039
regulation of anatomical structure morphogenesisGO:00226031300.039
connective tissue developmentGO:0061448990.039
maintenance of locationGO:005123540.039
system processGO:00030081850.039
histone phosphorylationGO:001657220.039
protein targeting to nucleusGO:004474430.038
mesoderm formationGO:0001707430.038
phosphorus metabolic processGO:00067931090.038
regenerationGO:0031099910.038
stem cell proliferationGO:007208940.038
growthGO:00400071740.037
regulation of intracellular protein transportGO:003315730.037
nucleic acid templated transcriptionGO:00976591810.037
camera type eye developmentGO:00430102220.036
single organism organelle organizationGO:19025891990.036
convergent extension involved in gastrulationGO:0060027710.035
cellular nitrogen compound metabolic processGO:00346412900.035
endoderm formationGO:0001706290.034
cell motilityGO:00488702440.034
determination of dorsal ventral asymmetryGO:0048262340.034
intracellular signal transductionGO:0035556850.034
primary neural tube formationGO:001402010.034
deathGO:00162651210.033
regulation of axon extensionGO:0030516240.033
renal system developmentGO:0072001940.033
negative regulation of biological processGO:00485193040.033
lateral line system developmentGO:0048925760.032
positive regulation of map kinase activityGO:004340630.032
response to growth factorGO:0070848390.032
regulation of cell communicationGO:00106462320.032
wnt signaling pathwayGO:0016055800.032
cellular macromolecular complex assemblyGO:0034622240.031
cell morphogenesisGO:00009022890.031
kidney developmentGO:0001822920.031
regulation of phosphate metabolic processGO:0019220430.031
anterior head developmentGO:009706520.031
regulation of reproductive processGO:200024140.030
rna metabolic processGO:00160702190.030
mediolateral intercalationGO:006003130.030
positive regulation of protein complex assemblyGO:003133420.030
regulation of cellular metabolic processGO:00313233200.030
endodermal cell fate specificationGO:0001714170.030
chemosensory behaviorGO:000763510.030
tube formationGO:0035148250.029
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
regulation of establishment of protein localizationGO:007020140.029
chemotaxisGO:00069351040.029
negative regulation of stem cell differentiationGO:200073720.029
nuclear importGO:005117030.029
regulation of protein catabolic processGO:004217610.029
actin cytoskeleton organizationGO:0030036630.029
neuron developmentGO:00486662620.028
regulation of biosynthetic processGO:00098892500.028
cell part morphogenesisGO:00329902460.028
fin developmentGO:0033333770.028
embryo development ending in birth or egg hatchingGO:00097922710.028
regulation of protein localization to nucleusGO:190018020.027
phosphate containing compound metabolic processGO:00067961080.027
spemann organizer formationGO:0060061100.027
negative regulation of signalingGO:0023057960.027
cellular component morphogenesisGO:00329893360.027
single organismal cell cell adhesionGO:0016337290.027
phagocytosisGO:000690930.027
protein complex subunit organizationGO:0071822460.026
taxisGO:00423301090.026
protein metabolic processGO:00195381830.026
establishment of protein localization to organelleGO:007259440.026
response to external stimulusGO:00096052640.026
blood vessel developmentGO:00015682460.026
skeletal system developmentGO:00015011810.025
lateral inhibitionGO:004633110.025
regulation of intracellular signal transductionGO:1902531570.025
cell surface receptor signaling pathwayGO:00071663250.025
regulation of embryonic developmentGO:0045995470.025
determination of dorsal identityGO:0048263130.025
regulation of myotube differentiationGO:001083020.025
single organism localizationGO:19025782250.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.024
gastrulation with mouth forming secondGO:0001702440.024
cytoskeleton organizationGO:0007010960.024
immune system developmentGO:00025201910.024
inner ear developmentGO:00488391260.024
transcription dna templatedGO:00063511810.024
transportGO:00068102200.024
positive regulation of cell cycleGO:004578730.023
regulation of phosphorus metabolic processGO:0051174430.023
single organism metabolic processGO:00447102170.023
eye field cell fate commitment involved in camera type eye formationGO:006089830.023
cell morphogenesis involved in differentiationGO:00009041950.023
regulation of mesoderm developmentGO:2000380110.022
cellular response to growth factor stimulusGO:0071363390.022
adherens junction organizationGO:003433240.022
cellular monovalent inorganic cation homeostasisGO:003000420.022
negative regulation of mapk cascadeGO:004340940.022
regulation of striated muscle tissue developmentGO:001620260.022
homeostatic processGO:00425921420.022
phosphorylationGO:0016310690.022
regulation of wound healingGO:006104120.022
generation of neuronsGO:00486993850.022
regulation of endodermal cell fate specificationGO:0042663150.022
compound eye developmentGO:004874920.022
positive regulation of transportGO:005105020.022
cellular protein metabolic processGO:00442671290.022
positive regulation of catabolic processGO:000989640.022
rna biosynthetic processGO:00327741810.021
mucopolysaccharide metabolic processGO:190351020.021
olfactory lobe developmentGO:002198840.021
canonical wnt signaling pathwayGO:0060070480.021
cytosolic calcium ion transportGO:006040130.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.021
cellular aromatic compound metabolic processGO:00067252950.021
regulation of cell differentiationGO:00455951420.021
regulation of response to external stimulusGO:0032101310.020
embryonic organ morphogenesisGO:00485622740.020
positive regulation of cellular amine metabolic processGO:003324000.020
cellular macromolecule metabolic processGO:00442603910.020
negative regulation of response to stimulusGO:00485851040.020
segmentationGO:0035282970.020
cellular protein catabolic processGO:004425740.020
regulation of locomotionGO:0040012550.020
post anal tail morphogenesisGO:0036342190.020
tissue regenerationGO:0042246740.020
centrosome cycleGO:000709810.020
cellular component biogenesisGO:00440851780.020
regulation of oocyte developmentGO:006028130.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.020
embryonic eye morphogenesisGO:0048048300.019
catenin import into nucleusGO:003541120.019
regulation of myelinationGO:003164110.019
muscle organ developmentGO:00075171010.019
positive regulation of transcription dna templatedGO:0045893570.019
developmental growthGO:00485891660.019
microtubule based processGO:0007017600.019
sensory organ morphogenesisGO:00905962000.019
macromolecule modificationGO:00434121110.019
cellular response to fibroblast growth factor stimulusGO:0044344220.019
embryonic camera type eye formationGO:0060900100.019
regulation of cell migrationGO:0030334400.019
regulation of anterior head developmentGO:200074220.018
cell fate specificationGO:0001708680.018
neuron projection extensionGO:1990138450.018
regulation of cellular amino acid metabolic processGO:000652100.018
regulation of cell developmentGO:00602841000.018
cell fate commitmentGO:0045165990.018
thrombocyte differentiationGO:000257440.018
biological adhesionGO:0022610400.018
regulation of reactive oxygen species metabolic processGO:200037720.018
positive regulation of striated muscle tissue developmentGO:004584410.018
negative regulation of multicellular organismal processGO:0051241690.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
cellular macromolecule biosynthetic processGO:00346452240.018
regulation of establishment of planar polarityGO:009017540.017
positive regulation of metabolic processGO:00098931080.017
cellular amine metabolic processGO:004410620.017
response to monosaccharideGO:003428430.017
organonitrogen compound metabolic processGO:1901564740.017
mesodermal cell fate specificationGO:0007501120.017
neuron projection morphogenesisGO:00488121610.017
regulation of cell shapeGO:000836010.017
amine metabolic processGO:000930820.017
regulation of catenin import into nucleusGO:003541220.017
mitotic cell cycleGO:0000278640.017
defense response to bacteriumGO:0042742220.017
head developmentGO:00603223030.017
positive regulation of muscle organ developmentGO:004863610.017
positive regulation of dna metabolic processGO:005105410.016
cellular protein modification processGO:00064641000.016
regulation of collateral sprouting in absence of injuryGO:004869640.016
nucleobase containing compound metabolic processGO:00061392740.016
regulation of tube sizeGO:003515020.016
eye developmentGO:00016542770.016
cellular component assemblyGO:00226071700.016
neural tube developmentGO:0021915620.016
skeletal muscle tissue developmentGO:0007519670.016
cell deathGO:00082191210.016
negative regulation of programmed cell deathGO:0043069580.016
regulation of syncytium formation by plasma membrane fusionGO:006014220.015
establishment of organelle localizationGO:0051656450.015
macromolecule biosynthetic processGO:00090592270.015
convergent extensionGO:00600261180.015
negative regulation of bmp signaling pathwayGO:0030514130.015
otic placode formationGO:0043049230.015
hepatic duct developmentGO:006101120.015
meiotic cell cycle processGO:190304630.015
otic vesicle formationGO:0030916270.015
pronephros developmentGO:0048793690.015
stem cell maintenanceGO:001982740.015
protein complex assemblyGO:0006461300.015
striated muscle tissue developmentGO:00147061100.015
neuron projection developmentGO:00311751800.015
protein polymerizationGO:005125840.015
nephron developmentGO:0072006310.015
heterocycle metabolic processGO:00464832900.014
calcium ion transport into cytosolGO:006040230.014
endodermal cell fate commitmentGO:0001711180.014
heterocycle biosynthetic processGO:00181302150.014
neural tube patterningGO:0021532330.014
epithelial tube formationGO:0072175190.014
striated muscle cell differentiationGO:00511461290.014
cell adhesionGO:0007155400.014
neurological system processGO:0050877620.014
cellular response to external stimulusGO:007149620.014
response to glucoseGO:000974930.014
negative regulation of protein kinase activityGO:000646940.014
regulation of cellular response to growth factor stimulusGO:0090287350.014
endodermal cell differentiationGO:0035987190.014
endodermal cell fate determinationGO:000749320.014
transcription from rna polymerase ii promoterGO:0006366800.014
positive regulation of jun kinase activityGO:004350720.014
lipid storageGO:001991510.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
cellular response to chemical stimulusGO:00708871570.014
midbrain developmentGO:0030901280.014
fibroblast growth factor receptor signaling pathwayGO:0008543220.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
protein modification processGO:00362111000.014
determination of left right asymmetry in diencephalonGO:003546240.014
anterior posterior pattern specificationGO:00099521520.014
nitric oxide biosynthetic processGO:000680920.014
hepatocyte proliferationGO:007257420.014
positive regulation of biosynthetic processGO:0009891680.014
mesenchyme developmentGO:00604851270.014
biosynthetic processGO:00090582940.014
small molecule metabolic processGO:0044281770.014
regulation of stem cell differentiationGO:200073640.014
regulation of cell motilityGO:2000145460.014
negative regulation of sequestering of calcium ionGO:005128340.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
renal filtrationGO:0097205100.013
inner ear receptor cell differentiationGO:0060113290.013
regulation of neurological system processGO:003164420.013
regulation of programmed cell deathGO:00430671010.013
reflexGO:006000420.013
regulation of rna biosynthetic processGO:20011412130.013
positive regulation of phospholipase c activityGO:001086310.013
regulation of developmental growthGO:0048638380.013
metal ion homeostasisGO:0055065260.013
negative regulation of axon extension involved in axon guidanceGO:004884310.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
response to hexoseGO:000974630.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
response to carbohydrateGO:000974330.013
regulation of endodermal cell differentiationGO:1903224150.013
angioblast cell migration involved in selective angioblast sproutingGO:003547540.013
regulation of purine nucleotide catabolic processGO:003312120.013
positive regulation of cellular catabolic processGO:003133130.013
cerebellar granular layer formationGO:002168430.013
regulation of cytokine productionGO:000181730.013
tissue migrationGO:0090130370.013
sprouting angiogenesisGO:0002040530.013
positive regulation of biological processGO:00485182530.012
regulation of cell sizeGO:0008361290.012
muscle structure developmentGO:00610611960.012
response to fibroblast growth factorGO:0071774220.012
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.012
regulation of erk1 and erk2 cascadeGO:007037240.012
regulation of cellular biosynthetic processGO:00313262450.012
regulation of cellular ketone metabolic processGO:001056570.012
regulation of epithelial cell proliferationGO:005067830.012
developmental growth involved in morphogenesisGO:0060560860.012
aminoglycan metabolic processGO:000602290.012
axon extensionGO:0048675450.012
negative regulation of protein localization to nucleusGO:190018120.012
morphogenesis of embryonic epitheliumGO:0016331300.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
mesodermal cell fate commitmentGO:0001710140.012
response to nutrientGO:000758430.012
actin filament polymerizationGO:003004120.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
response to woundingGO:00096111160.012
regulation of blood vessel sizeGO:005088020.012
defense response to fungusGO:005083220.012
microtubule cytoskeleton organizationGO:0000226330.012
cell proliferation in forebrainGO:002184630.012
actin filament organizationGO:0007015150.012
regulation of protein ubiquitinationGO:003139630.012
determination of ventral identityGO:0048264210.012
regulation of gtp catabolic processGO:003312420.012
positive regulation of cytoskeleton organizationGO:005149530.012
sensory organ developmentGO:00074233930.012
developmental programmed cell deathGO:001062340.012
embryonic limb morphogenesisGO:003032620.011
epithelial cilium movement involved in determination of left right asymmetryGO:006028780.011
ectodermal placode formationGO:0060788260.011
cellular response to extracellular stimulusGO:003166820.011
central nervous system developmentGO:00074173870.011
cerebellar granular layer morphogenesisGO:002168330.011
ear developmentGO:00435831270.011
cerebellar granule cell differentiationGO:002170730.011
negative regulation of kinase activityGO:003367340.011
forebrain regionalizationGO:002187140.011
organic cyclic compound biosynthetic processGO:19013622230.011
spinal cord anterior posterior patterningGO:002151210.011
diencephalon developmentGO:0021536580.011
protein complex biogenesisGO:0070271300.011
chondrocyte developmentGO:000206340.011
forebrain neuron differentiationGO:0021879140.011
circulatory system processGO:0003013870.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
cerebellar granular layer developmentGO:002168130.011
negative regulation of apoptotic processGO:0043066550.011
regulation of stem cell proliferationGO:007209120.011
wound healingGO:0042060900.011
phagocytosis engulfmentGO:000691110.011
developmental inductionGO:0031128100.011
positive regulation of multi organism processGO:004390230.011
oocyte maturationGO:000155640.011
determination of liver left right asymmetryGO:0071910110.011
regulation of axon extension involved in axon guidanceGO:004884160.011
cell projection morphogenesisGO:00488582440.011
cellular protein complex assemblyGO:0043623190.011
regulation of localizationGO:00328791040.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
dorsal convergenceGO:0060030140.011
regulation of gastrulationGO:0010470240.011
single organism intracellular transportGO:1902582250.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
axon developmentGO:00615641660.011
establishment of spindle localizationGO:0051293120.011
cellular component disassemblyGO:002241110.011
agingGO:000756820.011
olfactory bulb developmentGO:002177240.011
gall bladder developmentGO:006101010.011
synaptic target recognitionGO:000803910.011
non canonical wnt signaling pathwayGO:0035567130.010
single organism cell adhesionGO:0098602290.010
regulation of wnt signaling pathwayGO:0030111530.010
negative regulation of catabolic processGO:000989530.010
somitogenesisGO:0001756870.010
response to organic substanceGO:00100331530.010
regulation of biological qualityGO:00650082630.010
fin regenerationGO:0031101510.010
positive regulation of macromolecule metabolic processGO:0010604930.010
kidney epithelium developmentGO:0072073230.010
small gtpase mediated signal transductionGO:000726480.010
positive regulation of cellular biosynthetic processGO:0031328680.010
establishment of localizationGO:00512342440.010
cellular response to organic substanceGO:00713101050.010
regulation of nucleotide catabolic processGO:003081120.010
forebrain cell migrationGO:002188510.010
membrane invaginationGO:001032410.010
epithelial cell differentiationGO:00308551160.010
pronephric glomerulus developmentGO:0039021130.010
negative chemotaxisGO:005091910.010
muscle fiber developmentGO:0048747520.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.010

ier2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.025
sensory system diseaseDOID:005015500.015
auditory system diseaseDOID:274200.011