IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

traf4a

tnf receptor-associated factor 4a

(Aliases: MGC77418,traf4l,zgc:77418)

Entrez: 404045
ZFIN: ZDB-GENE-040308-1
Ensembl: ENSDARG00000003963
UniProtKB: Q7T1K2

Process Predictions
Disease Predictions

traf4a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
vasculature development	GO:0001944	278	0.960
blood vessel development	GO:0001568	246	0.954
neuron differentiation	GO:0030182	353	0.930
blood vessel morphogenesis	GO:0048514	216	0.928
sensory organ development	GO:0007423	393	0.927	Fly
eye development	GO:0001654	277	0.926	Fly
hematopoietic or lymphoid organ development	GO:0048534	191	0.911
morphogenesis of an epithelium	GO:0002009	333	0.908
cell morphogenesis involved in differentiation	GO:0000904	195	0.879	Fly
central nervous system development	GO:0007417	387	0.878
head development	GO:0060322	303	0.873
cellular component morphogenesis	GO:0032989	336	0.855	Fly
regulation of metabolic process	GO:0019222	359	0.845	Zebrafish Fly
positive regulation of biological process	GO:0048518	253	0.837	Zebrafish Fly
embryonic organ development	GO:0048568	381	0.826
aromatic compound biosynthetic process	GO:0019438	217	0.821	Zebrafish
brain development	GO:0007420	293	0.820
cell part morphogenesis	GO:0032990	246	0.809
regulation of multicellular organismal process	GO:0051239	277	0.806
localization of cell	GO:0051674	244	0.798
negative regulation of cellular process	GO:0048523	283	0.794
cell migration	GO:0016477	237	0.778
epithelial tube morphogenesis	GO:0060562	148	0.774
neuron development	GO:0048666	262	0.763
forebrain development	GO:0030900	96	0.752
heart morphogenesis	GO:0003007	156	0.730
gastrulation	GO:0007369	208	0.693	Fly
cellular component movement	GO:0006928	335	0.685	Fly
regulation of nervous system development	GO:0051960	90	0.680
eye morphogenesis	GO:0048592	144	0.675
cell motility	GO:0048870	244	0.667
organic substance biosynthetic process	GO:1901576	289	0.662	Zebrafish
heart development	GO:0007507	313	0.656
biosynthetic process	GO:0009058	294	0.646	Zebrafish
diencephalon development	GO:0021536	58	0.642
rna biosynthetic process	GO:0032774	181	0.630	Zebrafish
angiogenesis	GO:0001525	158	0.627
morphogenesis of a branching epithelium	GO:0061138	16	0.626
response to external stimulus	GO:0009605	264	0.625	Zebrafish Fly
locomotion	GO:0040011	313	0.616
immune system development	GO:0002520	191	0.584
cellular macromolecule metabolic process	GO:0044260	391	0.581	Zebrafish
intracellular signal transduction	GO:0035556	85	0.580	Fly
cell fate commitment	GO:0045165	99	0.560	Fly
cell projection morphogenesis	GO:0048858	244	0.556
cellular aromatic compound metabolic process	GO:0006725	295	0.555	Zebrafish
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.547	Zebrafish
mesenchymal cell development	GO:0014031	78	0.537
cell morphogenesis	GO:0000902	289	0.537	Fly
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.527
forebrain cell migration	GO:0021885	1	0.524
retina development in camera type eye	GO:0060041	146	0.523
generation of neurons	GO:0048699	385	0.518
segmentation	GO:0035282	97	0.516
patterning of blood vessels	GO:0001569	15	0.512
tube morphogenesis	GO:0035239	349	0.506	Fly
protein localization to nucleus	GO:0034504	3	0.486
endocrine system development	GO:0035270	65	0.479
organic cyclic compound metabolic process	GO:1901360	301	0.477	Zebrafish
regulation of cellular metabolic process	GO:0031323	320	0.476	Zebrafish Fly
cellular macromolecule biosynthetic process	GO:0034645	224	0.474	Zebrafish
neuron projection development	GO:0031175	180	0.474
negative regulation of biological process	GO:0048519	304	0.469
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.469	Zebrafish
gene expression	GO:0010467	252	0.469	Zebrafish
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.465
neuroblast proliferation	GO:0007405	2	0.464
nucleobase containing compound biosynthetic process	GO:0034654	205	0.441	Zebrafish
axon development	GO:0061564	166	0.439
positive regulation of biosynthetic process	GO:0009891	68	0.439	Zebrafish
mesenchyme development	GO:0060485	127	0.437
morphogenesis of a branching structure	GO:0001763	21	0.426
apoptotic process	GO:0006915	116	0.410	Fly
nucleobase containing compound metabolic process	GO:0006139	274	0.408	Zebrafish
regulation of rna metabolic process	GO:0051252	224	0.404	Zebrafish
axon guidance	GO:0007411	86	0.403
cell projection organization	GO:0030030	284	0.401
somite development	GO:0061053	96	0.400
cellular nitrogen compound metabolic process	GO:0034641	290	0.398	Zebrafish
regulation of multicellular organismal development	GO:2000026	223	0.392
mechanoreceptor differentiation	GO:0042490	37	0.387
negative regulation of multicellular organismal process	GO:0051241	69	0.376
regulation of signal transduction	GO:0009966	225	0.376	Fly
hair cell differentiation	GO:0035315	32	0.372
regulation of transcription dna templated	GO:0006355	213	0.371	Zebrafish
immune system process	GO:0002376	241	0.369	Zebrafish
regionalization	GO:0003002	274	0.369
regulation of macromolecule biosynthetic process	GO:0010556	225	0.369	Zebrafish
regulation of anatomical structure morphogenesis	GO:0022603	130	0.367
ventral spinal cord interneuron fate commitment	GO:0060579	3	0.365
regulation of rna biosynthetic process	GO:2001141	213	0.356	Zebrafish
mesenchymal cell differentiation	GO:0048762	87	0.352
regulation of axon extension	GO:0030516	24	0.351
positive regulation of developmental process	GO:0051094	50	0.350
lymphatic endothelial cell differentiation	GO:0060836	1	0.348
ear development	GO:0043583	127	0.344
regulation of cell development	GO:0060284	100	0.339
nucleocytoplasmic transport	GO:0006913	4	0.339
positive regulation of metabolic process	GO:0009893	108	0.331	Zebrafish Fly
rhombomere development	GO:0021546	19	0.330
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.316
stem cell proliferation	GO:0072089	4	0.314
skin development	GO:0043588	54	0.309
macromolecule biosynthetic process	GO:0009059	227	0.308	Zebrafish
stem cell differentiation	GO:0048863	117	0.308
cellular biosynthetic process	GO:0044249	286	0.308	Zebrafish
developmental growth	GO:0048589	166	0.305
somitogenesis	GO:0001756	87	0.300
heterocycle metabolic process	GO:0046483	290	0.300	Zebrafish
positive regulation of cellular process	GO:0048522	201	0.298	Zebrafish Fly
regulation of gene expression	GO:0010468	265	0.296	Zebrafish
negative regulation of collateral sprouting	GO:0048671	2	0.294
negative regulation of cellular biosynthetic process	GO:0031327	55	0.292
response to chemical	GO:0042221	320	0.284
regulation of neurogenesis	GO:0050767	87	0.284
developmental growth involved in morphogenesis	GO:0060560	86	0.273
regulation of macromolecule metabolic process	GO:0060255	317	0.271	Zebrafish
negative regulation of developmental process	GO:0051093	65	0.270
neuron projection guidance	GO:0097485	86	0.270
neuron migration	GO:0001764	22	0.269
liver development	GO:0001889	96	0.262
renal system development	GO:0072001	94	0.261
peripheral nervous system neuron differentiation	GO:0048934	28	0.260
endocrine pancreas development	GO:0031018	27	0.260
regulation of biosynthetic process	GO:0009889	250	0.258	Zebrafish
regulation of stem cell differentiation	GO:2000736	4	0.256
gliogenesis	GO:0042063	45	0.253
collateral sprouting in absence of injury	GO:0048669	4	0.253
outflow tract morphogenesis	GO:0003151	1	0.251
positive regulation of rna metabolic process	GO:0051254	59	0.250	Zebrafish
camera type eye morphogenesis	GO:0048593	108	0.245
negative regulation of cellular metabolic process	GO:0031324	77	0.244
regulation of epithelial cell proliferation	GO:0050678	3	0.242
embryonic organ morphogenesis	GO:0048562	274	0.234
lymphangiogenesis	GO:0001946	25	0.234
digestive system development	GO:0055123	289	0.234	Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.233	Zebrafish
inner ear development	GO:0048839	126	0.233
positive regulation of mesodermal cell fate specification	GO:0048337	1	0.232
branching morphogenesis of an epithelial tube	GO:0048754	15	0.232
signal transduction	GO:0007165	455	0.229	Fly
rna metabolic process	GO:0016070	219	0.223	Zebrafish
artery development	GO:0060840	22	0.222
cell surface receptor signaling pathway	GO:0007166	325	0.219
positive regulation of cell communication	GO:0010647	56	0.219	Fly
epithelial tube formation	GO:0072175	19	0.212
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.212	Zebrafish
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.212	Zebrafish
small molecule metabolic process	GO:0044281	77	0.211
retina morphogenesis in camera type eye	GO:0060042	79	0.207
nucleic acid metabolic process	GO:0090304	244	0.207	Zebrafish
morphogenesis of an epithelial sheet	GO:0002011	49	0.205
central nervous system myelination	GO:0022010	2	0.204
developmental cell growth	GO:0048588	52	0.204
facial nerve morphogenesis	GO:0021610	1	0.204
central nervous system neuron differentiation	GO:0021953	74	0.203
axonogenesis	GO:0007409	152	0.197
kidney development	GO:0001822	92	0.197
tissue remodeling	GO:0048771	4	0.197
axon ensheathment in central nervous system	GO:0032291	2	0.196
lateral line system development	GO:0048925	76	0.195
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.195
regulation of cellular component organization	GO:0051128	86	0.189
lymph vessel morphogenesis	GO:0036303	25	0.188
positive regulation of transport	GO:0051050	2	0.188
protein import into nucleus	GO:0006606	3	0.187
regulation of nucleic acid templated transcription	GO:1903506	213	0.184	Zebrafish
angioblast cell migration involved in selective angioblast sprouting	GO:0035475	4	0.182
specification of symmetry	GO:0009799	204	0.182
gland development	GO:0048732	143	0.179	Fly
sensory organ morphogenesis	GO:0090596	200	0.178
anterior posterior pattern specification	GO:0009952	152	0.177
hemopoiesis	GO:0030097	183	0.177
cellular protein modification process	GO:0006464	100	0.175
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.175	Zebrafish
regulation of primary metabolic process	GO:0080090	311	0.175	Zebrafish
ameboidal type cell migration	GO:0001667	143	0.174
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.173
regulation of cellular biosynthetic process	GO:0031326	245	0.171	Zebrafish
death	GO:0016265	121	0.167	Fly
hepaticobiliary system development	GO:0061008	98	0.165
regulation of biological quality	GO:0065008	263	0.163
response to stress	GO:0006950	263	0.162	Zebrafish Fly
nitrogen compound metabolic process	GO:0006807	319	0.159	Zebrafish
regulation of cell communication	GO:0010646	232	0.158	Fly
determination of left right symmetry	GO:0007368	179	0.157
regulation of stem cell proliferation	GO:0072091	2	0.156
pancreas development	GO:0031016	84	0.156
positive regulation of gene expression	GO:0010628	71	0.156	Zebrafish
regulation of cell motility	GO:2000145	46	0.155
larval development	GO:0002164	2	0.155
lymph vessel development	GO:0001945	27	0.153
renal tubule morphogenesis	GO:0061333	1	0.153
blood vessel endothelial cell proliferation involved in sprouting angiogenesis	GO:0002043	4	0.151
organic cyclic compound biosynthetic process	GO:1901362	223	0.151	Zebrafish
positive regulation of macromolecule metabolic process	GO:0010604	93	0.149	Zebrafish
growth	GO:0040007	174	0.145
protein targeting to nucleus	GO:0044744	3	0.145
otolith development	GO:0048840	32	0.144
negative regulation of biosynthetic process	GO:0009890	55	0.143
inner ear receptor cell differentiation	GO:0060113	29	0.143
embryonic appendage morphogenesis	GO:0035113	30	0.141
cell growth	GO:0016049	57	0.138
regulation of cellular ketone metabolic process	GO:0010565	7	0.137
positive regulation of cellular biosynthetic process	GO:0031328	68	0.137	Zebrafish
transcription from rna polymerase ii promoter	GO:0006366	80	0.137
negative regulation of rna metabolic process	GO:0051253	48	0.134
cell proliferation	GO:0008283	80	0.134
regulation of apoptotic process	GO:0042981	98	0.134	Fly
nephron tubule morphogenesis	GO:0072078	1	0.133
regulation of myelination	GO:0031641	1	0.133
negative regulation of nitrogen compound metabolic process	GO:0051172	59	0.129
regulation of glial cell differentiation	GO:0045685	4	0.129
epithelial cell differentiation	GO:0030855	116	0.128	Fly
peripheral nervous system development	GO:0007422	55	0.128
regulation of cellular component movement	GO:0051270	55	0.126
system process	GO:0003008	185	0.124
stem cell division	GO:0017145	1	0.123
chemotaxis	GO:0006935	104	0.120
kupffer s vesicle development	GO:0070121	50	0.119
positive regulation of cell fate commitment	GO:0010455	1	0.119
cell death	GO:0008219	121	0.118	Fly
positive regulation of nervous system development	GO:0051962	25	0.118
digestive tract morphogenesis	GO:0048546	231	0.117	Fly
chordate embryonic development	GO:0043009	271	0.116
positive regulation of multicellular organismal process	GO:0051240	52	0.116
regulation of developmental process	GO:0050793	247	0.116
regulation of mechanoreceptor differentiation	GO:0045631	1	0.114
cell fate specification	GO:0001708	68	0.114
gabaergic neuron differentiation	GO:0097154	2	0.113
protein import	GO:0017038	3	0.113
camera type eye development	GO:0043010	222	0.112
dorsal ventral pattern formation	GO:0009953	125	0.111
regulation of cell matrix adhesion	GO:0001952	1	0.111
rhombomere boundary formation	GO:0021654	10	0.110
aging	GO:0007568	2	0.106
neuron fate determination	GO:0048664	2	0.106
single organism metabolic process	GO:0044710	217	0.106	Fly
cellular response to stress	GO:0033554	62	0.105	Fly
regulation of intracellular protein transport	GO:0033157	3	0.105
neuron projection morphogenesis	GO:0048812	161	0.105
wound healing	GO:0042060	90	0.103
carboxylic acid metabolic process	GO:0019752	22	0.103
nuclear import	GO:0051170	3	0.102
urogenital system development	GO:0001655	97	0.101
sensory neuron axon guidance	GO:0097374	3	0.100
negative regulation of response to stimulus	GO:0048585	104	0.100
regulation of cell migration	GO:0030334	40	0.099
response to abiotic stimulus	GO:0009628	122	0.099
phosphorylation	GO:0016310	69	0.097	Fly
facial nerve development	GO:0021561	3	0.096
epidermis development	GO:0008544	48	0.095
regeneration	GO:0031099	91	0.094
peripheral nervous system neuron development	GO:0048935	22	0.093
hypochord development	GO:0055016	3	0.093
posterior lateral line system development	GO:0048915	46	0.091
establishment of protein localization to organelle	GO:0072594	4	0.090
nucleic acid templated transcription	GO:0097659	181	0.090	Zebrafish
photoreceptor cell differentiation	GO:0046530	55	0.090
endodermal cell fate commitment	GO:0001711	18	0.089
axon extension	GO:0048675	45	0.089
protein metabolic process	GO:0019538	183	0.088
transcription dna templated	GO:0006351	181	0.088	Zebrafish
somatic muscle development	GO:0007525	4	0.088
regulation of synapse assembly	GO:0051963	3	0.086
spinal cord motor neuron differentiation	GO:0021522	26	0.086
neurological system process	GO:0050877	62	0.086
regulation of localization	GO:0032879	104	0.086
macromolecule localization	GO:0033036	54	0.085	Fly
regulation of peptidyl tyrosine phosphorylation	GO:0050730	1	0.085
multicellular organismal signaling	GO:0035637	22	0.085
neural crest cell development	GO:0014032	62	0.085
cellular protein localization	GO:0034613	20	0.085
response to organic substance	GO:0010033	153	0.084
stem cell development	GO:0048864	82	0.084
tissue regeneration	GO:0042246	74	0.083
negative regulation of signaling	GO:0023057	96	0.083
pectoral fin development	GO:0033339	50	0.081
positive regulation of signal transduction	GO:0009967	56	0.081	Fly
renal tubule development	GO:0061326	5	0.081
epidermal cell differentiation	GO:0009913	36	0.080
regulation of establishment of protein localization	GO:0070201	4	0.080
regulation of inner ear receptor cell differentiation	GO:2000980	1	0.080
regulation of intracellular signal transduction	GO:1902531	57	0.079	Fly
establishment of localization	GO:0051234	244	0.078	Fly
vestibular receptor cell differentiation	GO:0060114	3	0.077
cerebellar granular layer formation	GO:0021684	3	0.077
cell cell recognition	GO:0009988	1	0.076
negative regulation of cell death	GO:0060548	60	0.076
positive regulation of transcription dna templated	GO:0045893	57	0.075	Zebrafish
oligodendrocyte differentiation	GO:0048709	23	0.075
cell migration involved in sprouting angiogenesis	GO:0002042	8	0.074
negative regulation of catalytic activity	GO:0043086	21	0.074
neuron projection extension	GO:1990138	45	0.073
cell cycle	GO:0007049	93	0.073
skeletal muscle organ development	GO:0060538	78	0.073
spinal cord development	GO:0021510	46	0.073
negative regulation of rna biosynthetic process	GO:1902679	45	0.073
cellular ketone metabolic process	GO:0042180	11	0.072
regulation of nitrogen compound metabolic process	GO:0051171	251	0.072	Zebrafish
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	48	0.071
digestive tract development	GO:0048565	265	0.070	Fly
positive regulation of mesoderm development	GO:2000382	1	0.070
protein localization	GO:0008104	40	0.069	Fly
defense response	GO:0006952	47	0.069	Zebrafish Fly
developmental maturation	GO:0021700	34	0.068
fin development	GO:0033333	77	0.067
cellular protein metabolic process	GO:0044267	129	0.067
venous endothelial cell migration involved in lymph vessel development	GO:0060855	4	0.067
sympathetic ganglion development	GO:0061549	2	0.067
programmed cell death	GO:0012501	119	0.066	Fly
neuronal stem cell maintenance	GO:0097150	2	0.066
lipid storage	GO:0019915	1	0.066
posterior lateral line neuromast hair cell differentiation	GO:0048923	8	0.066
positive regulation of macromolecule biosynthetic process	GO:0010557	59	0.066	Zebrafish
regulation of molecular function	GO:0065009	70	0.065
mesoderm development	GO:0007498	88	0.065
negative regulation of metabolic process	GO:0009892	86	0.065
limb bud formation	GO:0060174	2	0.064
neural crest cell differentiation	GO:0014033	72	0.064
regulation of neural precursor cell proliferation	GO:2000177	3	0.063
negative regulation of neuron differentiation	GO:0045665	10	0.063
radial glial cell differentiation	GO:0060019	2	0.063
cartilage development	GO:0051216	96	0.063
endothelial cell differentiation	GO:0045446	20	0.063
negative chemotaxis	GO:0050919	1	0.063
inner ear morphogenesis	GO:0042472	63	0.062
nuclear transport	GO:0051169	4	0.062
regulation of protein transport	GO:0051223	3	0.062
embryonic pectoral fin morphogenesis	GO:0035118	24	0.062
cardiac cell fate commitment	GO:0060911	1	0.061
negative regulation of nervous system development	GO:0051961	22	0.061
single organism nuclear import	GO:1902593	3	0.061
artery morphogenesis	GO:0048844	14	0.061
positive regulation of cellular metabolic process	GO:0031325	94	0.061	Zebrafish Fly
regulation of neuron projection development	GO:0010975	40	0.061
biological adhesion	GO:0022610	40	0.060
ventral spinal cord development	GO:0021517	35	0.060
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	22	0.059
neuron fate commitment	GO:0048663	26	0.059
amine metabolic process	GO:0009308	2	0.059
regulation of programmed cell death	GO:0043067	101	0.059	Fly
regulation of collateral sprouting	GO:0048670	7	0.058
negative regulation of axon extension involved in axon guidance	GO:0048843	1	0.058
positive regulation of cell proliferation	GO:0008284	15	0.057
regulation of cellular amine metabolic process	GO:0033238	0	0.057
cardiac chamber development	GO:0003205	19	0.057
neural retina development	GO:0003407	49	0.057
neuroblast differentiation	GO:0014016	1	0.057
regulation of developmental growth	GO:0048638	38	0.057
muscle cell fate determination	GO:0007521	1	0.056
negative regulation of chemotaxis	GO:0050922	4	0.056
forebrain neuron development	GO:0021884	7	0.056
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	42	0.056
embryonic eye morphogenesis	GO:0048048	30	0.055
proepicardium development	GO:0003342	4	0.055
b cell differentiation	GO:0030183	1	0.055
regulation of extrinsic apoptotic signaling pathway	GO:2001236	3	0.055
regulation of synapse organization	GO:0050807	3	0.055
determination of bilateral symmetry	GO:0009855	204	0.054
regulation of cell proliferation	GO:0042127	37	0.054
vasculogenesis	GO:0001570	41	0.054
heterocycle biosynthetic process	GO:0018130	215	0.053	Zebrafish
negative regulation of nucleic acid templated transcription	GO:1903507	45	0.053
pancreatic d cell differentiation	GO:0003311	2	0.053
negative regulation of apoptotic process	GO:0043066	55	0.053
inner ear receptor cell development	GO:0060119	20	0.052
negative regulation of neurogenesis	GO:0050768	20	0.052
ensheathment of neurons	GO:0007272	18	0.051
negative regulation of collateral sprouting of intact axon in response to injury	GO:0048685	2	0.051
endothelial cell fate commitment	GO:0060839	3	0.051
nephron tubule development	GO:0072080	4	0.050
transport	GO:0006810	220	0.049	Fly
nephron morphogenesis	GO:0072028	2	0.049
regulation of collateral sprouting in absence of injury	GO:0048696	4	0.049
macromolecule modification	GO:0043412	111	0.049
microtubule polymerization	GO:0046785	2	0.049
embryonic pattern specification	GO:0009880	44	0.049
regulation of signaling	GO:0023051	235	0.049	Fly
establishment of localization in cell	GO:0051649	77	0.048
regulation of response to stimulus	GO:0048583	269	0.048	Fly
positive regulation of rna biosynthetic process	GO:1902680	57	0.048	Zebrafish
negative regulation of stem cell differentiation	GO:2000737	2	0.047
negative regulation of macromolecule biosynthetic process	GO:0010558	48	0.047
synaptic growth at neuromuscular junction	GO:0051124	2	0.047
organic acid metabolic process	GO:0006082	31	0.046
cell fate commitment involved in pattern specification	GO:0060581	6	0.046
connective tissue development	GO:0061448	99	0.045
septum transversum development	GO:0003343	4	0.045
stem cell fate commitment	GO:0048865	1	0.045
muscle organ development	GO:0007517	101	0.044
striated muscle tissue development	GO:0014706	110	0.044
cellular amine metabolic process	GO:0044106	2	0.044
regulation of neuron differentiation	GO:0045664	56	0.044
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	1	0.044
axon ensheathment	GO:0008366	18	0.044
cranial nerve development	GO:0021545	42	0.044
axis specification	GO:0009798	43	0.043
neural crest cell migration	GO:0001755	42	0.043
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.043
phosphorus metabolic process	GO:0006793	109	0.043	Fly
lateral line development	GO:0048882	66	0.043
pancreatic d cell development	GO:0003324	1	0.042
central nervous system neuron development	GO:0021954	29	0.042
branchiomotor neuron axon guidance	GO:0021785	1	0.042
negative regulation of macromolecule metabolic process	GO:0010605	76	0.042
regulation of jak stat cascade	GO:0046425	3	0.041
neuroblast fate commitment	GO:0014017	1	0.041
innervation	GO:0060384	3	0.041
posterior lateral line development	GO:0048916	38	0.041
regulation of nucleocytoplasmic transport	GO:0046822	2	0.041
regulation of protein localization to nucleus	GO:1900180	2	0.040
startle response	GO:0001964	4	0.040
regulation of cell death	GO:0010941	103	0.040	Fly
regulation of mesodermal cell fate specification	GO:0042661	9	0.040
positive regulation of protein metabolic process	GO:0051247	23	0.040
negative regulation of axon guidance	GO:1902668	1	0.039
regulation of cellular amino acid metabolic process	GO:0006521	0	0.039
embryonic heart tube morphogenesis	GO:0003143	108	0.039
cellular response to chemical stimulus	GO:0070887	157	0.039
receptor internalization	GO:0031623	2	0.038
negative regulation of gene expression	GO:0010629	65	0.038
negative regulation of molecular function	GO:0044092	23	0.038
peptidyl tyrosine modification	GO:0018212	5	0.038
positive regulation of cell fate specification	GO:0042660	1	0.038
regulation of angiogenesis	GO:0045765	26	0.038
cognition	GO:0050890	1	0.038
astrocyte differentiation	GO:0048708	1	0.038
pectoral fin morphogenesis	GO:0035138	29	0.037
negative regulation of kinase activity	GO:0033673	4	0.037
negative regulation of programmed cell death	GO:0043069	58	0.037
notochord development	GO:0030903	54	0.037
protein phosphorylation	GO:0006468	47	0.037
cardiac atrium morphogenesis	GO:0003209	2	0.036
cardiac atrium development	GO:0003230	4	0.036
regulation of locomotion	GO:0040012	55	0.036
regulation of cell size	GO:0008361	29	0.036
forebrain generation of neurons	GO:0021872	14	0.035
hematopoietic stem cell differentiation	GO:0060218	20	0.035
positive regulation of cellular amine metabolic process	GO:0033240	0	0.035
positive regulation of muscle tissue development	GO:1901863	1	0.034
regulation of protein import into nucleus	GO:0042306	2	0.034
nephron epithelium morphogenesis	GO:0072088	1	0.034
segment specification	GO:0007379	12	0.034
cell differentiation in spinal cord	GO:0021515	40	0.034
b cell activation	GO:0042113	2	0.034
regulation of cell projection organization	GO:0031344	44	0.034
myeloid cell differentiation	GO:0030099	86	0.034
selective angioblast sprouting	GO:0035474	5	0.033
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	1	0.033
kidney morphogenesis	GO:0060993	15	0.033
negative regulation of cell differentiation	GO:0045596	46	0.033
i kappab kinase nf kappab signaling	GO:0007249	4	0.032
positive regulation of muscle organ development	GO:0048636	1	0.032
single organism localization	GO:1902578	225	0.032	Fly
positive regulation of cell death	GO:0010942	29	0.032	Fly
patterning of lymph vessels	GO:0060854	1	0.032
neuromast development	GO:0048884	46	0.032
positive regulation of gliogenesis	GO:0014015	2	0.032
stem cell maintenance	GO:0019827	4	0.032
ear morphogenesis	GO:0042471	64	0.032
positive regulation of catalytic activity	GO:0043085	25	0.031
posterior lateral line neuromast primordium migration	GO:0048920	12	0.031
negative regulation of cell growth	GO:0030308	7	0.031
glial cell development	GO:0021782	20	0.031
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	8	0.031
single organism cell adhesion	GO:0098602	29	0.030
semicircular canal morphogenesis	GO:0048752	18	0.030
positive regulation of neuron differentiation	GO:0045666	12	0.030
positive regulation of catabolic process	GO:0009896	4	0.030
regulation of metal ion transport	GO:0010959	4	0.030
positive regulation of cell cycle	GO:0045787	3	0.030
positive regulation of secretion by cell	GO:1903532	1	0.030
intracellular transport	GO:0046907	32	0.029
protein modification process	GO:0036211	100	0.029
negative regulation of transcription dna templated	GO:0045892	45	0.029
appendage development	GO:0048736	80	0.029
positive regulation of signaling	GO:0023056	56	0.029	Fly
negative regulation of cell development	GO:0010721	26	0.029
appendage morphogenesis	GO:0035107	56	0.029
homeostatic process	GO:0042592	142	0.029
negative regulation of endothelial cell migration	GO:0010596	1	0.029
positive regulation of molecular function	GO:0044093	33	0.029
peripheral nervous system neuron axonogenesis	GO:0048936	13	0.028
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.028
morphogenesis of embryonic epithelium	GO:0016331	30	0.028
embryonic epithelial tube formation	GO:0001838	17	0.028
positive regulation of neurogenesis	GO:0050769	24	0.028
positive regulation of apoptotic signaling pathway	GO:2001235	1	0.028
mapk cascade	GO:0000165	18	0.028	Fly
posterior lateral line neuromast mantle cell differentiation	GO:0048924	1	0.028
convergent extension	GO:0060026	118	0.028
inositol lipid mediated signaling	GO:0048017	2	0.028
neuron remodeling	GO:0016322	1	0.028
positive regulation of secretion	GO:0051047	1	0.028
regulation of mapk cascade	GO:0043408	14	0.027	Fly
positive regulation of stem cell proliferation	GO:2000648	1	0.027
aorta morphogenesis	GO:0035909	3	0.027

traf4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.033

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