Danio rerio

0 known processes

clic2

chloride intracellular channel 2

(Aliases: zgc:92762)

clic2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell activationGO:005086510.201
response to external stimulusGO:00096052640.168
Fly
ion transportGO:00068111140.114
Fly
small molecule metabolic processGO:0044281770.107
regulation of cytokine productionGO:000181730.103
response to stressGO:00069502630.102
Fly
response to chemicalGO:00422213200.096
Fly
proteolysis involved in cellular protein catabolic processGO:005160330.095
response to inorganic substanceGO:0010035380.091
positive regulation of cell activationGO:005086710.087
heart developmentGO:00075073130.082
larval developmentGO:000216420.080
single organism localizationGO:19025782250.078
Fly
embryonic organ developmentGO:00485683810.077
single fertilizationGO:000733830.077
positive regulation of transportGO:005105020.077
positive regulation of cytokine productionGO:000181920.075
muscle tissue developmentGO:00605371100.075
regulation of primary metabolic processGO:00800903110.073
organonitrogen compound metabolic processGO:1901564740.070
regulation of cellular extravasationGO:000269110.066
collagen metabolic processGO:003296320.066
response to alkaloidGO:004327920.065
regulation of intracellular protein transportGO:003315730.062
nucleotide metabolic processGO:0009117280.062
regulation of cell shapeGO:000836010.062
astrocyte differentiationGO:004870810.061
single organism metabolic processGO:00447102170.061
regulation of transporter activityGO:003240920.060
positive regulation of cellular component biogenesisGO:004408930.059
nuclear transportGO:005116940.058
nuclear importGO:005117030.057
cellular component morphogenesisGO:00329893360.057
regulation of biological qualityGO:00650082630.056
regulation of cellular macromolecule biosynthetic processGO:20001122220.052
protein import into nucleusGO:000660630.051
negative regulation of cytokine productionGO:000181810.050
positive regulation of cellular catabolic processGO:003133130.050
nucleocytoplasmic transportGO:000691340.049
cellular localizationGO:0051641970.049
regulation of establishment of protein localizationGO:007020140.048
establishment of localizationGO:00512342440.048
Fly
positive regulation of cellular processGO:00485222010.048
superoxide metabolic processGO:000680120.048
positive regulation of biological processGO:00485182530.047
cellular response to chemical stimulusGO:00708871570.046
cell deathGO:00082191210.046
phagocytosisGO:000690930.046
muscle structure developmentGO:00610611960.046
cellular response to external stimulusGO:007149620.046
biological adhesionGO:0022610400.045
sensory system developmentGO:0048880760.044
startle responseGO:000196440.043
cellular component movementGO:00069283350.043
multicellular organismal macromolecule metabolic processGO:004425920.042
regulation of circadian rhythmGO:004275240.041
sensory organ developmentGO:00074233930.041
maintenance of locationGO:005123540.041
negative regulation of cellular processGO:00485232830.040
regulation of transmembrane transporter activityGO:002289820.040
transportGO:00068102200.040
Fly
regulation of immune system processGO:0002682340.040
purine containing compound metabolic processGO:0072521290.039
defense responseGO:0006952470.039
lipid storageGO:001991510.037
reactive oxygen species biosynthetic processGO:190340910.036
nucleic acid metabolic processGO:00903042440.036
regulation of protein transportGO:005122330.036
positive regulation of nucleoside metabolic processGO:004597910.036
antimicrobial humoral responseGO:001973020.036
response to organic substanceGO:00100331530.036
Fly
morphogenesis of an epitheliumGO:00020093330.036
agingGO:000756820.035
Fly
response to drugGO:004249330.035
regulation of multicellular organism growthGO:004001440.035
cellular extravasationGO:004512310.035
regulation of ion transmembrane transporter activityGO:003241220.035
cellular nitrogen compound metabolic processGO:00346412900.035
carboxylic acid metabolic processGO:0019752220.034
carbohydrate derivative metabolic processGO:1901135610.034
regulation of cytoplasmic transportGO:190364940.034
establishment of protein localization to organelleGO:007259440.033
positive regulation of cellular extravasationGO:000269310.033
positive regulation of purine nucleotide catabolic processGO:003312310.033
lateral line system developmentGO:0048925760.032
response to carbohydrateGO:000974330.032
regulation of blood vessel sizeGO:005088020.032
regulation of nucleotide catabolic processGO:003081120.031
homeostatic processGO:00425921420.031
response to nitrogen compoundGO:1901698190.031
central nervous system developmentGO:00074173870.031
phosphate containing compound metabolic processGO:00067961080.031
regulation of protein catabolic processGO:004217610.031
wound healingGO:0042060900.030
muscle organ developmentGO:00075171010.030
regulation of localizationGO:00328791040.030
organophosphate metabolic processGO:0019637370.030
response to lipopolysaccharideGO:0032496130.030
regulation of nucleocytoplasmic transportGO:004682220.029
nitrogen compound metabolic processGO:00068073190.029
cell morphogenesisGO:00009022890.029
multicellular organismal metabolic processGO:004423620.029
macromolecule biosynthetic processGO:00090592270.028
positive regulation of catabolic processGO:000989640.028
cytoskeleton organizationGO:0007010960.028
positive regulation of leukocyte differentiationGO:190210710.028
cytokinesisGO:000091030.028
regulation of gene expressionGO:00104682650.027
apoptotic processGO:00069151160.027
protein metabolic processGO:00195381830.027
cell motilityGO:00488702440.027
response to amino acidGO:004320020.027
regulation of metal ion transportGO:001095940.027
cellular macromolecule metabolic processGO:00442603910.027
regulation of macromolecule metabolic processGO:00602553170.026
nucleobase containing compound metabolic processGO:00061392740.026
regulation of multicellular organismal processGO:00512392770.026
locomotionGO:00400113130.026
Fly
response to metal ionGO:0010038340.026
rna localizationGO:000640340.026
response to amineGO:001407510.026
immune system developmentGO:00025201910.026
regulation of response to stimulusGO:00485832690.026
system processGO:00030081850.026
ribonucleotide metabolic processGO:0009259270.025
regulation of tube sizeGO:003515020.025
nuclear exportGO:005116810.025
transmembrane transportGO:00550851200.025
Fly
regulation of membrane potentialGO:0042391230.025
immune responseGO:0006955280.025
cellular component disassemblyGO:002241110.025
regulation of protein targetingGO:190353320.025
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.024
spermatid differentiationGO:004851520.024
protein importGO:001703830.024
cell activationGO:0001775160.024
cellular carbohydrate metabolic processGO:004426240.024
regulation of calcium ion transportGO:005192420.024
embryo development ending in birth or egg hatchingGO:00097922710.024
regulation of circadian sleep wake cycleGO:004274910.024
regulation of cellular component organizationGO:0051128860.024
single organism organelle organizationGO:19025891990.024
purine nucleotide metabolic processGO:0006163270.023
protein localization to plasma membraneGO:007265910.023
regulation of catalytic activityGO:0050790550.023
organic acid metabolic processGO:0006082310.023
protein targeting to nucleusGO:004474430.023
cellular protein catabolic processGO:004425740.023
response to endogenous stimulusGO:0009719830.023
organic substance transportGO:0071702580.023
g1 s transition of mitotic cell cycleGO:000008210.023
lipid metabolic processGO:0006629520.023
regulation of inflammatory responseGO:005072720.022
response to oxygen containing compoundGO:1901700550.022
Fly
positive regulation of metabolic processGO:00098931080.022
regulation of alcohol biosynthetic processGO:190293010.022
single organism nuclear importGO:190259330.022
positive regulation of immune effector processGO:000269930.022
positive regulation of gtp catabolic processGO:003312610.022
regulation of protein complex assemblyGO:004325430.021
negative regulation of biological processGO:00485193040.021
spermatid developmentGO:000728620.021
response to abiotic stimulusGO:00096281220.021
Fly
cellular response to extracellular stimulusGO:003166820.021
single organism transportGO:00447652060.021
Fly
membrane hyperpolarizationGO:006008110.020
regulation of cellular carbohydrate metabolic processGO:001067540.020
negative regulation of metabolic processGO:0009892860.020
cellular macromolecule biosynthetic processGO:00346452240.020
cardiac atrium morphogenesisGO:000320920.020
negative regulation of macromolecule metabolic processGO:0010605760.020
nucleoside phosphate metabolic processGO:0006753280.020
striated muscle cell differentiationGO:00511461290.020
negative regulation of cellular metabolic processGO:0031324770.020
regulation of biosynthetic processGO:00098892500.020
brain developmentGO:00074202930.020
tube morphogenesisGO:00352393490.019
gtp metabolic processGO:004603940.019
regulation of cellular ketone metabolic processGO:001056570.019
oxoacid metabolic processGO:0043436310.019
protein localization to nucleusGO:003450430.019
oxidation reduction processGO:0055114410.019
g2 m transition of mitotic cell cycleGO:000008640.019
intracellular transportGO:0046907320.019
eye developmentGO:00016542770.019
heart valve formationGO:000318840.019
cellular protein metabolic processGO:00442671290.019
innate immune responseGO:0045087130.019
detection of chemical stimulusGO:000959340.019
fertilizationGO:000956630.019
cellular amino acid metabolic processGO:000652070.019
response to acid chemicalGO:0001101170.019
circadian sleep wake cycle sleepGO:005080210.019
protein targeting to membraneGO:000661210.019
angiogenesisGO:00015251580.019
regulation of cellular metabolic processGO:00313233200.019
regulation of signalingGO:00230512350.019
cellular component assembly involved in morphogenesisGO:00109271070.019
regulation of cell deathGO:00109411030.018
cellular response to molecule of bacterial originGO:007121930.018
hemopoiesisGO:00300971830.018
regulation of myeloid leukocyte differentiationGO:000276150.018
carbohydrate biosynthetic processGO:001605110.018
phosphorylationGO:0016310690.018
cell adhesionGO:0007155400.018
cell matrix adhesionGO:000716040.018
regulation of system processGO:0044057400.018
signal transductionGO:00071654550.018
protein complex disassemblyGO:004324110.018
positive regulation of macromolecule metabolic processGO:0010604930.018
protein secretionGO:000930610.018
endosomal transportGO:001619720.018
blood circulationGO:0008015870.018
regulation of reproductive processGO:200024140.018
regulation of wound healingGO:006104120.017
positive regulation of defense responseGO:003134990.017
heterocycle metabolic processGO:00464832900.017
multicellular organism growthGO:003526440.017
regulation of molecular functionGO:0065009700.017
regulation of protein import into nucleusGO:004230620.017
muscle cell differentiationGO:00426921390.017
stem cell maintenanceGO:001982740.017
negative regulation of cell deathGO:0060548600.017
regulation of cytokine biosynthetic processGO:004203510.017
gtp catabolic processGO:000618420.017
cell cycle g1 s phase transitionGO:004484310.017
single organism membrane fusionGO:004480120.017
cellular biosynthetic processGO:00442492860.017
positive regulation of cellular metabolic processGO:0031325940.017
multicellular organismal homeostasisGO:0048871290.017
tissue regenerationGO:0042246740.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
activation of mapk activityGO:000018730.016
regulation of cellular amino acid metabolic processGO:000652100.016
response to external biotic stimulusGO:0043207970.016
actin polymerization or depolymerizationGO:000815420.016
guanosine containing compound catabolic processGO:190106920.016
interspecies interaction between organismsGO:004441940.016
regulation of protein localization to nucleusGO:190018020.016
striated muscle tissue developmentGO:00147061100.016
membrane fusionGO:006102520.016
organelle organizationGO:00069962270.016
head developmentGO:00603223030.016
homeostasis of number of cellsGO:0048872620.016
regulation of reactive oxygen species metabolic processGO:200037720.016
cation transportGO:0006812810.016
response to organic cyclic compoundGO:0014070510.016
regulation of nucleoside metabolic processGO:000911820.016
modification dependent protein catabolic processGO:001994130.015
erythrocyte homeostasisGO:0034101550.015
response to glucoseGO:000974930.015
cellular response to nutrient levelsGO:003166920.015
regulation of leukocyte migrationGO:000268580.015
positive regulation of myeloid leukocyte differentiationGO:000276310.015
protein polymerizationGO:005125840.015
response to hexoseGO:000974630.015
chemical homeostasisGO:0048878490.015
programmed cell deathGO:00125011190.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
cell cycle g2 m phase transitionGO:004483940.014
ribonucleoside monophosphate catabolic processGO:000915840.014
reactive oxygen species metabolic processGO:007259360.014
compound eye developmentGO:004874920.014
regulation of cellular amine metabolic processGO:003323800.014
regulation of carbohydrate metabolic processGO:000610940.014
regulation of response to external stimulusGO:0032101310.014
transcription dna templatedGO:00063511810.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
purine ribonucleotide metabolic processGO:0009150270.014
regulation of cell matrix adhesionGO:000195210.014
localization of cellGO:00516742440.014
cellular component biogenesisGO:00440851780.014
regulation of metabolic processGO:00192223590.014
regulation of cellular biosynthetic processGO:00313262450.014
myeloid leukocyte differentiationGO:0002573150.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
hindbrain developmentGO:0030902910.014
hepaticobiliary system developmentGO:0061008980.014
regulation of nucleotide metabolic processGO:0006140170.014
rna transportGO:005065820.014
regulation of nitrogen compound metabolic processGO:00511712510.014
macromolecular complex disassemblyGO:003298410.014
regulation of apoptotic processGO:0042981980.014
regulation of multicellular organismal developmentGO:20000262230.014
regulation of purine nucleotide metabolic processGO:1900542170.014
circulatory system processGO:0003013870.014
blood coagulationGO:0007596120.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
cellular ketone metabolic processGO:0042180110.014
neuron differentiationGO:00301823530.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
positive regulation of map kinase activityGO:004340630.013
stem cell divisionGO:001714510.013
nucleoside monophosphate catabolic processGO:000912540.013
cortical actin cytoskeleton organizationGO:003086610.013
regulation of circadian sleep wake cycle sleepGO:004518710.013
regulation of protein localization to plasma membraneGO:190307610.013
mitotic dna integrity checkpointGO:004477440.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
vasculature developmentGO:00019442780.013
proteasomal protein catabolic processGO:001049820.013
regulation of gtpase activityGO:004308720.013
determination of heart left right asymmetryGO:00613711170.013
vasculogenesisGO:0001570410.013
establishment of localization in cellGO:0051649770.013
regulation of dna replicationGO:000627530.013
regulation of protein metabolic processGO:0051246560.013
cognitionGO:005089010.013
guanosine containing compound metabolic processGO:190106840.013
cellular component maintenanceGO:004395430.013
establishment of protein localization to membraneGO:009015030.013
atp catabolic processGO:000620040.013
amine metabolic processGO:000930820.013
cellular response to reactive oxygen speciesGO:003461420.013
regulation of phosphate metabolic processGO:0019220430.013
camera type eye morphogenesisGO:00485931080.013
response to biotic stimulusGO:0009607970.013
response to hormoneGO:0009725480.013
establishment of protein localization to plasma membraneGO:009000210.012
exocytosisGO:000688710.012
regulation of heart contractionGO:0008016320.012
positive regulation of nucleotide catabolic processGO:003081310.012
digestive tract morphogenesisGO:00485462310.012
ubiquitin dependent protein catabolic processGO:000651130.012
ion transmembrane transportGO:0034220910.012
Fly
positive regulation of cellular amino acid metabolic processGO:004576400.012
myeloid cell homeostasisGO:0002262560.012
protein localizationGO:0008104400.012
single organism membrane organizationGO:0044802200.012
positive regulation of cell deathGO:0010942290.012
organic cyclic compound biosynthetic processGO:19013622230.012
regulation of rho protein signal transductionGO:003502320.012
regulation of developmental processGO:00507932470.012
heart processGO:0003015710.012
actomyosin structure organizationGO:0031032530.012
cellular response to biotic stimulusGO:007121630.012
circadian sleep wake cycleGO:004274520.012
positive regulation of secretion by cellGO:190353210.012
immune system processGO:00023762410.012
negative regulation of gene expressionGO:0010629650.012
positive regulation of catalytic activityGO:0043085250.012
striated muscle cell developmentGO:00550021080.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
regulation of glial cell differentiationGO:004568540.012
cell cycle arrestGO:000705010.012
negative regulation of cellular biosynthetic processGO:0031327550.011
positive regulation of myeloid cell differentiationGO:004563920.011
metal ion homeostasisGO:0055065260.011
small gtpase mediated signal transductionGO:000726480.011
regulation of muscle contractionGO:000693730.011
embryonic heart tube developmentGO:00350501330.011
appendage developmentGO:0048736800.011
neuromuscular processGO:005090570.011
regulation of synaptic plasticityGO:004816710.011
carbohydrate derivative biosynthetic processGO:1901137430.011
nucleic acid templated transcriptionGO:00976591810.011
fin developmentGO:0033333770.011
phosphorus metabolic processGO:00067931090.011
production of molecular mediator of immune responseGO:000244020.011
digestive tract developmentGO:00485652650.011
cellular response to lipopolysaccharideGO:007122230.011
neurological system processGO:0050877620.011
response to lipidGO:0033993600.011
regulation of programmed cell deathGO:00430671010.011
organelle assemblyGO:00709251100.011
heart loopingGO:0001947940.011
regulation of hydrolase activityGO:0051336280.011
generation of neuronsGO:00486993850.011
negative regulation of developmental processGO:0051093650.011
positive regulation of apoptotic processGO:0043065290.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
protein modification by small protein removalGO:007064610.011
leukocyte activationGO:0045321120.011
blood vessel developmentGO:00015682460.011
organic substance biosynthetic processGO:19015762890.011
smooth muscle contractionGO:000693920.011
epithelial cell differentiationGO:00308551160.011
epithelial tube morphogenesisGO:00605621480.011
regulation of organ growthGO:004662030.011
i kappab kinase nf kappab signalingGO:000724940.010
camera type eye developmentGO:00430102220.010
regulation of cellular protein metabolic processGO:0032268520.010
mesenchymal cell developmentGO:0014031780.010
mitotic cell cycleGO:0000278640.010
negative regulation of defense responseGO:003134820.010
circadian sleep wake cycle processGO:002241020.010
heart contractionGO:0060047710.010
actin cytoskeleton organizationGO:0030036630.010
positive regulation of wound healingGO:009030310.010
glial cell differentiationGO:0010001420.010
homeostasis of number of cells within a tissueGO:004887340.010
cellular aromatic compound metabolic processGO:00067252950.010
multi organism processGO:00517041340.010
regulation of defense responseGO:0031347140.010
heterocycle biosynthetic processGO:00181302150.010
macromolecule localizationGO:0033036540.010
nucleobase containing small molecule metabolic processGO:0055086320.010

clic2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
immune system diseaseDOID:291400.046
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
disease of metabolismDOID:001466700.018
organ system cancerDOID:005068600.011