Danio rerio

7 known processes

ppm1e

protein phosphatase 1E (PP2C domain containing)

ppm1e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:005089010.078
positive regulation of transportGO:005105020.066
larval developmentGO:000216420.064
embryonic organ developmentGO:00485683810.056
generation of neuronsGO:00486993850.048
adult behaviorGO:003053420.046
establishment of protein localization to organelleGO:007259440.045
regulation of multicellular organismal processGO:00512392770.045
nucleobase containing compound metabolic processGO:00061392740.044
sleepGO:003043110.040
stem cell maintenanceGO:001982740.040
protein localization to nucleusGO:003450430.040
cell surface receptor signaling pathwayGO:00071663250.040
regulation of protein complex assemblyGO:004325430.039
regulation of cellular metabolic processGO:00313233200.039
positive regulation of cellular component biogenesisGO:004408930.039
cell projection morphogenesisGO:00488582440.039
response to drugGO:004249330.039
heart developmentGO:00075073130.038
regulation of synapse assemblyGO:005196330.037
amine metabolic processGO:000930820.037
signal transductionGO:00071654550.036
cellular aromatic compound metabolic processGO:00067252950.036
neuron differentiationGO:00301823530.036
sensory organ developmentGO:00074233930.036
regulation of synapse organizationGO:005080730.036
regulation of establishment of protein localizationGO:007020140.036
cell projection organizationGO:00300302840.035
synaptic growth at neuromuscular junctionGO:005112420.034
system processGO:00030081850.034
positive regulation of cellular catabolic processGO:003133130.034
single organism transportGO:00447652060.034
morphogenesis of an epitheliumGO:00020093330.033
cell morphogenesis involved in differentiationGO:00009041950.033
cell morphogenesisGO:00009022890.033
regulation of reproductive processGO:200024140.032
single organism localizationGO:19025782250.032
cellular component morphogenesisGO:00329893360.032
central nervous system developmentGO:00074173870.032
neuron neuron synaptic transmissionGO:000727010.031
maintenance of locationGO:005123540.031
positive regulation of catabolic processGO:000989640.031
rna metabolic processGO:00160702190.031
cellular macromolecule metabolic processGO:00442603910.031
Zebrafish
transportGO:00068102200.031
locomotionGO:00400113130.031
single organism nuclear importGO:190259330.031
sensory organ morphogenesisGO:00905962000.031
nucleic acid metabolic processGO:00903042440.030
embryonic organ morphogenesisGO:00485622740.030
cellular amine metabolic processGO:004410620.030
regulation of circadian rhythmGO:004275240.030
regulation of biological qualityGO:00650082630.030
peptidyl serine modificationGO:001820920.030
response to chemicalGO:00422213200.030
regulation of cellular amine metabolic processGO:003323800.029
cell part morphogenesisGO:00329902460.029
cellular nitrogen compound metabolic processGO:00346412900.029
peptidyl serine phosphorylationGO:001810510.029
regulation of signal transductionGO:00099662250.029
regulation of macromolecule metabolic processGO:00602553170.029
nuclear transportGO:005116940.029
cell motilityGO:00488702440.029
heterocycle metabolic processGO:00464832900.029
muscle structure developmentGO:00610611960.029
negative regulation of protein phosphorylationGO:000193340.029
locomotor rhythmGO:004547530.029
growthGO:00400071740.029
adherens junction organizationGO:003433240.028
g protein coupled receptor signaling pathwayGO:0007186740.028
regulation of developmental processGO:00507932470.028
camera type eye developmentGO:00430102220.028
protein importGO:001703830.028
agingGO:000756820.028
protein targeting to nucleusGO:004474430.028
leukocyte proliferationGO:007066110.028
chemosensory behaviorGO:000763510.027
multicellular organism growthGO:003526440.027
regulation of localizationGO:00328791040.027
regulation of primary metabolic processGO:00800903110.027
organelle organizationGO:00069962270.027
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
regulation of mrna processingGO:005068430.027
regulation of protein transportGO:005122330.027
neuron developmentGO:00486662620.027
gene expressionGO:00104672520.027
regulation of multicellular organism growthGO:004001440.026
regulation of cell projection assemblyGO:006049140.026
establishment of localizationGO:00512342440.026
cellular component movementGO:00069283350.026
ubiquitin dependent protein catabolic processGO:000651130.026
regulation of metabolic processGO:00192223590.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
proteasomal protein catabolic processGO:001049820.025
regulation of cytokine productionGO:000181730.025
cell substrate adhesionGO:003158940.025
regulation of cytoplasmic transportGO:190364940.025
chordate embryonic developmentGO:00430092710.025
regulation of metal ion transportGO:001095940.025
regulation of gene expressionGO:00104682650.025
regulation of nitrogen compound metabolic processGO:00511712510.025
protein import into nucleusGO:000660630.025
neurological system processGO:0050877620.024
regulation of signalingGO:00230512350.024
nucleocytoplasmic transportGO:000691340.024
meiotic nuclear divisionGO:000712640.024
regulation of protein catabolic processGO:004217610.024
single organism organelle organizationGO:19025891990.024
actin polymerization or depolymerizationGO:000815420.024
blood vessel developmentGO:00015682460.024
modification dependent macromolecule catabolic processGO:004363230.024
cellular ketone metabolic processGO:0042180110.024
cellular protein catabolic processGO:004425740.024
regulation of cellular amino acid metabolic processGO:000652100.023
cell matrix adhesionGO:000716040.023
immune system processGO:00023762410.023
response to alkaloidGO:004327920.023
regulation of sodium ion transportGO:000202820.023
nuclear importGO:005117030.023
regulation of response to stimulusGO:00485832690.023
negative regulation of protein kinase activityGO:000646940.022
regulation of transmembrane transporter activityGO:002289820.022
cellular component assemblyGO:00226071700.022
regulation of multicellular organismal developmentGO:20000262230.022
negative regulation of kinase activityGO:003367340.022
lipid storageGO:001991510.022
compound eye developmentGO:004874920.022
meiotic cell cycle processGO:190304630.022
positive regulation of cell cycleGO:004578730.022
organic cyclic compound metabolic processGO:19013603010.022
regulation of nucleocytoplasmic transportGO:004682220.022
phagocytosisGO:000690930.022
positive regulation of biological processGO:00485182530.021
cell migrationGO:00164772370.021
gtp catabolic processGO:000618420.021
modification dependent protein catabolic processGO:001994130.021
regulation of macromolecule biosynthetic processGO:00105562250.021
small molecule metabolic processGO:0044281770.021
tube morphogenesisGO:00352393490.021
regulation of protein polymerizationGO:003227120.021
regulation of synaptic plasticityGO:004816710.021
guanosine containing compound metabolic processGO:190106840.021
guanosine containing compound catabolic processGO:190106920.021
muscle cell differentiationGO:00426921390.021
positive regulation of cytoskeleton organizationGO:005149530.021
regulation of cell activationGO:005086510.021
positive regulation of cellular processGO:00485222010.021
regulation of protein import into nucleusGO:004230620.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
transmembrane transportGO:00550851200.021
regulation of biosynthetic processGO:00098892500.021
regulation of cell substrate adhesionGO:001081010.021
gtp metabolic processGO:004603940.021
regulation of cell shapeGO:000836010.020
response to carbohydrateGO:000974330.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
response to organic substanceGO:00100331530.020
nitrogen compound metabolic processGO:00068073190.020
eye developmentGO:00016542770.020
vasculature developmentGO:00019442780.020
regulation of meiotic cell cycleGO:005144510.019
brain developmentGO:00074202930.019
female sex differentiationGO:004666040.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
positive regulation of protein complex assemblyGO:003133420.019
regulation of transcription dna templatedGO:00063552130.019
response to external stimulusGO:00096052640.019
response to stressGO:00069502630.019
striated muscle tissue developmentGO:00147061100.019
cellular response to radiationGO:007147840.019
regulation of cell communicationGO:00106462320.019
regulation of bindingGO:005109830.019
single organism metabolic processGO:00447102170.019
cellular response to chemical stimulusGO:00708871570.019
cellular component assembly involved in morphogenesisGO:00109271070.019
regulation of protein targetingGO:190353320.019
regulation of protein localization to nucleusGO:190018020.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
determination of bilateral symmetryGO:00098552040.018
cellular response to oxygen levelsGO:007145310.018
axonogenesisGO:00074091520.018
stem cell proliferationGO:007208940.018
retina development in camera type eyeGO:00600411460.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
mononuclear cell proliferationGO:003294310.018
regulation of locomotionGO:0040012550.018
regulation of transporter activityGO:003240920.018
regulation of ion transmembrane transporter activityGO:003241220.018
synaptic vesicle localizationGO:009747910.018
regulation of cellular ketone metabolic processGO:001056570.018
cellular carbohydrate metabolic processGO:004426240.018
blood vessel morphogenesisGO:00485142160.018
positive regulation of cell activationGO:005086710.018
hormone secretionGO:004687920.018
response to uvGO:000941130.017
regulation of intracellular protein transportGO:003315730.017
developmental growthGO:00485891660.017
negative regulation of cellular processGO:00485232830.017
post embryonic organ developmentGO:004856940.017
cellular amide metabolic processGO:004360340.017
nucleobase containing compound biosynthetic processGO:00346542050.017
cellular amino acid metabolic processGO:000652070.017
extrinsic apoptotic signaling pathwayGO:009719130.017
aromatic compound biosynthetic processGO:00194382170.017
lymphocyte proliferationGO:004665110.017
rna biosynthetic processGO:00327741810.017
regulation of dendrite morphogenesisGO:004881430.017
cellular response to extracellular stimulusGO:003166820.017
organelle assemblyGO:00709251100.017
regulation of nucleoside metabolic processGO:000911820.017
protein secretionGO:000930610.017
actin filament polymerizationGO:003004120.017
regulation of rna metabolic processGO:00512522240.017
homeostatic processGO:00425921420.017
regulation of dendrite developmentGO:005077330.017
cellular response to light stimulusGO:007148240.017
olfactory lobe developmentGO:002198840.016
behaviorGO:0007610740.016
organonitrogen compound metabolic processGO:1901564740.016
response to hexoseGO:000974630.016
protein polymerizationGO:005125840.016
protein metabolic processGO:00195381830.016
Zebrafish
macromolecule biosynthetic processGO:00090592270.016
positive regulation of cytokine productionGO:000181920.016
ion transmembrane transportGO:0034220910.016
response to monosaccharideGO:003428430.016
oxoacid metabolic processGO:0043436310.016
cytokinesisGO:000091030.016
olfactory bulb developmentGO:002177240.016
organic acid metabolic processGO:0006082310.016
negative regulation of protein transportGO:005122430.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
head developmentGO:00603223030.016
peptidyl threonine phosphorylationGO:001810710.016
b cell activationGO:004211320.016
positive regulation of cellular amine metabolic processGO:003324000.016
cellular response to decreased oxygen levelsGO:003629410.016
regulation of cell differentiationGO:00455951420.016
hormone transportGO:000991420.016
neuron projection developmentGO:00311751800.016
neuron projection morphogenesisGO:00488121610.016
embryonic heart tube morphogenesisGO:00031431080.016
angiogenesisGO:00015251580.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of wound healingGO:006104120.016
muscle cell developmentGO:00550011150.016
cellular protein metabolic processGO:00442671290.015
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.015
regulation of inflammatory responseGO:005072720.015
positive regulation of protein polymerizationGO:003227320.015
cellular component biogenesisGO:00440851780.015
regulation of nucleotide catabolic processGO:003081120.015
biosynthetic processGO:00090582940.015
regulation of blood pressureGO:000821710.015
startle responseGO:000196440.015
regulation of cell matrix adhesionGO:000195210.015
positive regulation of nucleoside metabolic processGO:004597910.015
heterocycle biosynthetic processGO:00181302150.015
regulation of neuronal synaptic plasticityGO:004816810.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
negative regulation of synapse assemblyGO:005196420.015
regulation of stem cell differentiationGO:200073640.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
smooth muscle contractionGO:000693920.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
digestive tract morphogenesisGO:00485462310.015
cellular biosynthetic processGO:00442492860.015
positive regulation of metabolic processGO:00098931080.015
regulation of tube sizeGO:003515020.015
positive regulation of secretionGO:005104710.015
regulation of calcium ion transportGO:005192420.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regionalizationGO:00030022740.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
golgi vesicle transportGO:004819330.014
regulation of carbohydrate metabolic processGO:000610940.014
deathGO:00162651210.014
localization of cellGO:00516742440.014
cellular response to hypoxiaGO:007145610.014
meiotic chromosome segregationGO:004513230.014
regulation of reactive oxygen species metabolic processGO:200037720.014
female gonad developmentGO:000858540.014
specification of symmetryGO:00097992040.014
striated muscle cell developmentGO:00550021080.014
hemopoiesisGO:00300971830.014
peptidyl threonine modificationGO:001821010.014
circulatory system processGO:0003013870.014
intracellular signal transductionGO:0035556850.014
protein dephosphorylationGO:000647030.014
Zebrafish
negative regulation of protein serine threonine kinase activityGO:007190120.014
regulation of filopodium assemblyGO:005148920.014
somatic stem cell maintenanceGO:003501910.014
development of primary female sexual characteristicsGO:004654540.014
striated muscle cell differentiationGO:00511461290.014
nucleic acid templated transcriptionGO:00976591810.014
regulation of growth rateGO:004000910.014
exocytosisGO:000688710.014
regulation of muscle contractionGO:000693730.014
immune system developmentGO:00025201910.014
response to amineGO:001407510.014
skeletal system developmentGO:00015011810.014
regulation of transportGO:0051049450.014
phagocytosis engulfmentGO:000691110.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
sensory perception of painGO:001923310.014
response to other organismGO:0051707970.014
heart morphogenesisGO:00030071560.014
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
phosphate containing compound metabolic processGO:00067961080.014
regulation of mrna splicing via spliceosomeGO:004802430.014
neuroblast proliferationGO:000740520.014
autophagyGO:000691440.014
eye morphogenesisGO:00485921440.014
positive regulation of map kinase activityGO:004340630.014
cellular component disassemblyGO:002241110.014
ion transportGO:00068111140.014
regulation of anatomical structure morphogenesisGO:00226031300.013
cation transmembrane transportGO:0098655650.013
regulation of cell migrationGO:0030334400.013
cell deathGO:00082191210.013
cell cycle arrestGO:000705010.013
cell substrate junction assemblyGO:000704420.013
regulation of blood vessel sizeGO:005088020.013
secondary metabolic processGO:001974830.013
synaptic vesicle transportGO:004848910.013
response to corticosteroidGO:003196010.013
response to abiotic stimulusGO:00096281220.013
regulation of rna biosynthetic processGO:20011412130.013
cellular response to external stimulusGO:007149620.013
regulation of apoptotic processGO:0042981980.013
protein localization to plasma membraneGO:007265910.013
response to amphetamineGO:000197510.013
regulation of membrane potentialGO:0042391230.013
membrane invaginationGO:001032410.013
endocrine processGO:005088620.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
organic substance biosynthetic processGO:19015762890.013
positive regulation of nucleotide catabolic processGO:003081310.013
regulation of cellular protein catabolic processGO:190336210.013
mesenchyme developmentGO:00604851270.013
regulation of cell deathGO:00109411030.013
neurotransmitter transportGO:000683620.013
lamellipodium organizationGO:009758110.013
carboxylic acid metabolic processGO:0019752220.013
digestive system developmentGO:00551232890.013
camera type eye morphogenesisGO:00485931080.013
lipid homeostasisGO:005508830.012
protein modification processGO:00362111000.012
Zebrafish
negative regulation of metabolic processGO:0009892860.012
tissue remodelingGO:004877140.012
regulation of neural precursor cell proliferationGO:200017730.012
germ line stem cell maintenanceGO:003071820.012
regulation of protein ubiquitinationGO:003139630.012
determination of left right symmetryGO:00073681790.012
regulation of neuron differentiationGO:0045664560.012
lipid catabolic processGO:001604240.012
cellular protein modification processGO:00064641000.012
Zebrafish
ear developmentGO:00435831270.012
regulation of organ growthGO:004662030.012
negative regulation of biological processGO:00485193040.012
response to glucoseGO:000974930.012
positive regulation of cell adhesionGO:004578510.012
negative regulation of defense responseGO:003134820.012
inner ear developmentGO:00488391260.012
multicellular organismal response to stressGO:003355520.012
embryonic skeletal joint morphogenesisGO:006027230.012
negative regulation of stem cell differentiationGO:200073720.012
apoptotic processGO:00069151160.012
somatic muscle developmentGO:000752540.012
positive regulation of secretion by cellGO:190353210.012
glial cell migrationGO:000834730.012
internal protein amino acid acetylationGO:000647520.012
gland developmentGO:00487321430.012
neuromuscular process controlling balanceGO:005088530.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
mitochondrion organizationGO:000700540.012
carbohydrate homeostasisGO:003350010.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
adherens junction assemblyGO:003433310.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
central nervous system neuron differentiationGO:0021953740.012
regulation of nervous system developmentGO:0051960900.012
interspecies interaction between organismsGO:004441940.012
positive regulation of reproductive processGO:200024320.012
alternative mrna splicing via spliceosomeGO:000038010.012
inorganic ion transmembrane transportGO:0098660570.012
retina morphogenesis in camera type eyeGO:0060042790.012
neurotransmitter secretionGO:000726920.012
response to external biotic stimulusGO:0043207970.012
digestive tract developmentGO:00485652650.012
regulation of ion transmembrane transportGO:0034765180.012
inorganic cation transmembrane transportGO:0098662500.012
stem cell divisionGO:001714510.012
cellular response to starvationGO:000926710.012
regulation of endocrine processGO:004406020.011
small molecule catabolic processGO:004428230.011
determination of heart left right asymmetryGO:00613711170.011
establishment of synaptic vesicle localizationGO:009748010.011
organic cyclic compound biosynthetic processGO:19013622230.011
response to light stimulusGO:0009416460.011
cell projection assemblyGO:0030031640.011
axon developmentGO:00615641660.011
positive regulation of multi organism processGO:004390230.011
regulation of protein bindingGO:004339330.011
response to amino acidGO:004320020.011
epithelial tube morphogenesisGO:00605621480.011
positive regulation of gtpase activityGO:004354710.011
regulation of gtpase activityGO:004308720.011
monoamine transportGO:001584410.011
positive regulation of gtp catabolic processGO:003312610.011
peptidyl lysine acetylationGO:001839420.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
antimicrobial humoral responseGO:001973020.011
regulation of stem cell proliferationGO:007209120.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
spinal cord developmentGO:0021510460.011
locomotory behaviorGO:0007626340.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
rna localizationGO:000640340.011
response to radiationGO:0009314510.011
phosphorus metabolic processGO:00067931090.011
cytoskeleton organizationGO:0007010960.011
multi organism processGO:00517041340.011
transcription dna templatedGO:00063511810.011
gastrulationGO:00073692080.011
cellular macromolecule biosynthetic processGO:00346452240.011
i kappab kinase nf kappab signalingGO:000724940.011
positive regulation of translationGO:004572710.011
negative regulation of mapk cascadeGO:004340940.011
regulation of cell motilityGO:2000145460.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
production of molecular mediator of immune responseGO:000244020.011
regulation of gtp catabolic processGO:003312420.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
regulation of lipid transportGO:003236840.011
response to xenobiotic stimulusGO:0009410450.011
regulation of dna replicationGO:000627530.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
negative regulation of macromolecule metabolic processGO:0010605760.011
organelle fusionGO:004828430.011
cortical cytoskeleton organizationGO:003086510.011
regulation of neurogenesisGO:0050767870.011
protein complex disassemblyGO:004324110.011
membrane fusionGO:006102520.011
response to woundingGO:00096111160.011
b cell mediated immunityGO:001972430.011
embryonic heart tube developmentGO:00350501330.011
macromolecular complex disassemblyGO:003298410.011
regulation of cellular component organizationGO:0051128860.011
sequestering of calcium ionGO:005120830.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
protein homooligomerizationGO:005126030.011
ribonucleoside monophosphate catabolic processGO:000915840.011
developmental programmed cell deathGO:001062340.011
regulation of cellular component movementGO:0051270550.011
regulation of phGO:000688530.011
negative regulation of cytoplasmic transportGO:190365020.010
embryonic skeletal system developmentGO:0048706970.010
peptide transportGO:001583310.010
nuclear migrationGO:000709730.010
glucose homeostasisGO:004259310.010
cellular response to organic substanceGO:00713101050.010
negative regulation of secretionGO:005104820.010
atp catabolic processGO:000620040.010
internal peptidyl lysine acetylationGO:001839320.010
negative regulation of dna metabolic processGO:005105340.010
stem cell differentiationGO:00488631170.010
taxisGO:00423301090.010
response to topologically incorrect proteinGO:003596620.010
protein acetylationGO:000647320.010
muscle tissue developmentGO:00605371100.010
regulation of wnt signaling pathwayGO:0030111530.010
chemotaxisGO:00069351040.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
wnt signaling pathwayGO:0016055800.010
mesenchymal cell developmentGO:0014031780.010
cellular response to molecule of bacterial originGO:007121930.010
notochord developmentGO:0030903540.010
synaptic vesicle endocytosisGO:004848810.010
sympathetic nervous system developmentGO:004848530.010
cellular response to reactive oxygen speciesGO:003461420.010

ppm1e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.014
organ system cancerDOID:005068600.013
musculoskeletal system diseaseDOID:1700.012