Danio rerio

0 known processes

ehd2

EH-domain containing 2

(Aliases: zgc:77671,fj66d02,wu:fj66d02)

ehd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal processGO:00512392770.473
response to amino acidGO:004320020.363
single organism localizationGO:19025782250.291
Human Worm
cellular component morphogenesisGO:00329893360.276
positive regulation of biological processGO:00485182530.269
Worm
regulation of developmental processGO:00507932470.239
signal transductionGO:00071654550.232
regulation of metabolic processGO:00192223590.231
system processGO:00030081850.200
regulation of signalingGO:00230512350.195
larval developmentGO:000216420.194
embryonic organ developmentGO:00485683810.183
regulation of cellular metabolic processGO:00313233200.181
regulation of response to stimulusGO:00485832690.181
cell substrate adhesionGO:003158940.179
regulation of cell communicationGO:00106462320.154
cell morphogenesisGO:00009022890.143
regulation of biological qualityGO:00650082630.141
positive regulation of catabolic processGO:000989640.140
nucleobase containing compound metabolic processGO:00061392740.136
Worm
notochord developmentGO:0030903540.130
response to drugGO:004249330.121
biosynthetic processGO:00090582940.121
regulation of signal transductionGO:00099662250.113
gene expressionGO:00104672520.110
regulation of multicellular organismal developmentGO:20000262230.108
positive regulation of cellular catabolic processGO:003133130.108
heterocycle metabolic processGO:00464832900.108
Worm
cell migrationGO:00164772370.103
agingGO:000756820.102
muscle fiber developmentGO:0048747520.101
cellular response to external stimulusGO:007149620.101
cellular component assemblyGO:00226071700.097
multicellular organism growthGO:003526440.097
fin morphogenesisGO:0033334530.097
transcription dna templatedGO:00063511810.096
cellular component biogenesisGO:00440851780.094
cellular component assembly involved in morphogenesisGO:00109271070.094
muscle structure developmentGO:00610611960.093
regulation of primary metabolic processGO:00800903110.093
cell adhesionGO:0007155400.092
neurological system processGO:0050877620.092
positive regulation of developmental processGO:0051094500.091
macromolecule biosynthetic processGO:00090592270.090
regulation of wound healingGO:006104120.088
locomotionGO:00400113130.088
nitrogen compound metabolic processGO:00068073190.088
Worm
response to chemicalGO:00422213200.085
protein heterooligomerizationGO:005129110.085
regulation of nucleobase containing compound metabolic processGO:00192192500.083
single organism metabolic processGO:00447102170.082
Worm
response to glucoseGO:000974930.081
positive regulation of cellular component biogenesisGO:004408930.081
sensory organ developmentGO:00074233930.080
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.080
establishment of localizationGO:00512342440.080
Human Worm Fly
digestive tract developmentGO:00485652650.080
cellular component movementGO:00069283350.079
biological adhesionGO:0022610400.079
cell surface receptor signaling pathwayGO:00071663250.079
cellular response to nutrient levelsGO:003166920.078
organic cyclic compound biosynthetic processGO:19013622230.077
positive regulation of response to stimulusGO:0048584800.077
chordate embryonic developmentGO:00430092710.077
regulation of gene expressionGO:00104682650.077
collagen metabolic processGO:003296320.077
cellular macromolecule biosynthetic processGO:00346452240.076
embryo development ending in birth or egg hatchingGO:00097922710.075
Worm
stem cell maintenanceGO:001982740.074
muscle cell differentiationGO:00426921390.074
regulation of nucleic acid templated transcriptionGO:19035062130.074
meiotic nuclear divisionGO:000712640.073
Worm
skeletal muscle organ developmentGO:0060538780.072
regulation of cell differentiationGO:00455951420.071
single organismal cell cell adhesionGO:0016337290.071
response to carbohydrateGO:000974330.069
protein trimerizationGO:007020640.068
oocyte anterior posterior axis specificationGO:000731440.068
multicellular organismal macromolecule metabolic processGO:004425920.068
organic cyclic compound metabolic processGO:19013603010.066
Worm
response to external stimulusGO:00096052640.066
heart developmentGO:00075073130.066
maternal determination of anterior posterior axis embryoGO:000835840.066
nucleobase containing compound biosynthetic processGO:00346542050.066
response to nutrientGO:000758430.065
cellular macromolecule metabolic processGO:00442603910.065
regulation of multicellular organism growthGO:004001440.064
fin developmentGO:0033333770.063
head developmentGO:00603223030.063
skeletal muscle tissue developmentGO:0007519670.062
heterocycle biosynthetic processGO:00181302150.062
positive regulation of macromolecule metabolic processGO:0010604930.061
negative regulation of signalingGO:0023057960.061
multicellular organismal metabolic processGO:004423620.060
cellular response to extracellular stimulusGO:003166820.060
regulation of systemic arterial blood pressureGO:000307310.059
endosomal transportGO:001619720.059
Human Worm
response to external biotic stimulusGO:0043207970.059
convergent extensionGO:00600261180.059
protein polymerizationGO:005125840.059
positive regulation of signal transductionGO:0009967560.058
regulation of macromolecule metabolic processGO:00602553170.058
renal system process involved in regulation of blood volumeGO:000197710.058
eye developmentGO:00016542770.058
positive regulation of nucleoside metabolic processGO:004597910.057
localization of cellGO:00516742440.057
regulation of transcription dna templatedGO:00063552130.055
nucleic acid metabolic processGO:00903042440.055
regulation of cellular macromolecule biosynthetic processGO:20001122220.054
cellular response to chemical stimulusGO:00708871570.053
muscle organ developmentGO:00075171010.053
pole plasm assemblyGO:000731540.053
blood vessel developmentGO:00015682460.053
maintenance of locationGO:005123540.052
stem cell differentiationGO:00488631170.052
mesenchymal cell differentiationGO:0048762870.052
transportGO:00068102200.052
Human Worm Fly
vasculature developmentGO:00019442780.051
developmental growthGO:00485891660.051
single organism cell adhesionGO:0098602290.050
negative regulation of cellular processGO:00485232830.049
appendage morphogenesisGO:0035107560.049
Fly
negative regulation of signal transductionGO:0009968940.049
cell fate commitmentGO:0045165990.048
collagen fibril organizationGO:003019910.048
digestive tract morphogenesisGO:00485462310.048
aromatic compound biosynthetic processGO:00194382170.048
skeletal system developmentGO:00015011810.047
tube morphogenesisGO:00352393490.047
regulation of embryonic developmentGO:0045995470.047
protein homooligomerizationGO:005126030.047
positive regulation of wound healingGO:009030310.047
gtp metabolic processGO:004603940.047
regulation of cell substrate adhesionGO:001081010.046
regionalizationGO:00030022740.046
Fly
regulation of cell morphogenesisGO:0022604420.046
adherens junction organizationGO:003433240.046
compound eye developmentGO:004874920.046
positive regulation of cellular metabolic processGO:0031325940.046
regulation of cellular biosynthetic processGO:00313262450.046
cell morphogenesis involved in differentiationGO:00009041950.046
regulation of cellular component organizationGO:0051128860.046
macromolecular complex subunit organizationGO:0043933740.045
regulation of nitrogen compound metabolic processGO:00511712510.045
response to organic substanceGO:00100331530.044
cell matrix adhesionGO:000716040.044
macromolecule localizationGO:0033036540.044
regulation of protein complex assemblyGO:004325430.044
regulation of stem cell differentiationGO:200073640.044
organic substance biosynthetic processGO:19015762890.043
wound healingGO:0042060900.043
rna metabolic processGO:00160702190.043
tissue remodelingGO:004877140.043
immune system processGO:00023762410.043
gtp catabolic processGO:000618420.042
positive regulation of blood circulationGO:190352420.042
circulatory system processGO:0003013870.042
regulation of blood pressureGO:000821710.042
response to hexoseGO:000974630.042
positive regulation of signalingGO:0023056560.041
positive regulation of i kappab kinase nf kappab signalingGO:004312330.041
regulation of anatomical structure morphogenesisGO:00226031300.041
myelin assemblyGO:003228810.041
outflow tract morphogenesisGO:000315110.041
mesenchyme developmentGO:00604851270.041
regulation of cell developmentGO:00602841000.041
striated muscle cell differentiationGO:00511461290.040
cell deathGO:00082191210.040
Worm
rna localizationGO:000640340.040
cell motilityGO:00488702440.040
cartilage developmentGO:0051216960.040
actin polymerization or depolymerizationGO:000815420.040
stem cell proliferationGO:007208940.039
cellular nitrogen compound metabolic processGO:00346412900.039
Worm
response to monosaccharideGO:003428430.039
axon ensheathmentGO:0008366180.039
regulation of synapse assemblyGO:005196330.039
positive regulation of nucleobase containing compound metabolic processGO:0045935690.038
extracellular structure organizationGO:0043062270.038
positive regulation of nitrogen compound metabolic processGO:0051173690.037
digestive system developmentGO:00551232890.037
nucleic acid templated transcriptionGO:00976591810.037
myotube differentiationGO:0014902450.037
negative regulation of biological processGO:00485193040.036
heart morphogenesisGO:00030071560.036
positive regulation of canonical wnt signaling pathwayGO:009026340.036
fin regenerationGO:0031101510.036
regulation of bindingGO:005109830.036
intracellular mrna localizationGO:000829810.035
response to abiotic stimulusGO:00096281220.035
blood circulationGO:0008015870.035
single organism organelle organizationGO:19025891990.035
regulation of cell activationGO:005086510.035
cellular carbohydrate metabolic processGO:004426240.035
regulation of cell adhesionGO:0030155150.035
lipid storageGO:001991510.035
response to hydrogen peroxideGO:004254230.034
positive regulation of cell differentiationGO:0045597300.034
anterior posterior axis specificationGO:0009948200.034
angiogenesisGO:00015251580.034
skeletal system morphogenesisGO:00487051020.033
positive regulation of metabolic processGO:00098931080.033
segmentationGO:0035282970.033
positive regulation of cell communicationGO:0010647560.033
cell projection assemblyGO:0030031640.033
morphogenesis of an epitheliumGO:00020093330.033
positive regulation of purine nucleotide catabolic processGO:003312310.033
cell projection morphogenesisGO:00488582440.033
cytoplasm organizationGO:000702840.033
response to vitaminGO:003327330.033
cellular response to organic cyclic compoundGO:0071407380.032
regulation of protein polymerizationGO:003227120.032
positive regulation of cellular processGO:00485222010.032
Worm
negative regulation of protein complex assemblyGO:003133310.032
growthGO:00400071740.032
regulation of cellular amine metabolic processGO:003323800.032
protein localization to plasma membraneGO:007265910.032
organelle fusionGO:004828430.032
germ line stem cell maintenanceGO:003071820.031
regulation of blood vessel sizeGO:005088020.031
cell part morphogenesisGO:00329902460.031
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
positive regulation of cell activationGO:005086710.030
glucose homeostasisGO:004259310.030
tissue regenerationGO:0042246740.030
actin filament polymerizationGO:003004120.030
formation of primary germ layerGO:0001704620.030
phosphate containing compound metabolic processGO:00067961080.030
Worm
phosphorus metabolic processGO:00067931090.030
Worm
organonitrogen compound metabolic processGO:1901564740.030
Worm
positive regulation of gene expressionGO:0010628710.030
actin filament based processGO:0030029640.030
response to lipidGO:0033993600.030
guanosine containing compound metabolic processGO:190106840.030
phagocytosisGO:000690930.030
muscle cell developmentGO:00550011150.030
sphingolipid biosynthetic processGO:003014820.029
regulation of locomotionGO:0040012550.029
embryonic organ morphogenesisGO:00485622740.029
protein complex subunit organizationGO:0071822460.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
hematopoietic or lymphoid organ developmentGO:00485341910.029
muscle tissue developmentGO:00605371100.029
regulation of membrane potentialGO:0042391230.028
amine metabolic processGO:000930820.028
connective tissue developmentGO:0061448990.028
regulation of epithelial to mesenchymal transitionGO:001071730.028
cellular response to endogenous stimulusGO:0071495680.028
dorsal ventral pattern formationGO:00099531250.028
cellular response to retinoic acidGO:007130010.028
regulation of biosynthetic processGO:00098892500.028
intracellular signal transductionGO:0035556850.028
small molecule metabolic processGO:0044281770.028
Worm
rna biosynthetic processGO:00327741810.028
regulation of localizationGO:00328791040.028
response to growth factorGO:0070848390.027
positive regulation of proteolysisGO:0045862100.027
renal filtrationGO:0097205100.027
regulation of synapse organizationGO:005080730.027
positive regulation of cell cycleGO:004578730.027
protein complex assemblyGO:0006461300.027
protein metabolic processGO:00195381830.027
transmission of nerve impulseGO:0019226190.027
guanosine containing compound catabolic processGO:190106920.027
chondrocyte developmentGO:000206340.027
regulation of erk1 and erk2 cascadeGO:007037240.027
protein localization to nucleusGO:003450430.027
carbohydrate homeostasisGO:003350010.027
zymogen activationGO:003163830.026
single organism transportGO:00447652060.026
Human Worm
positive regulation of multicellular organismal processGO:0051240520.026
regulation of peptidase activityGO:0052547230.026
organelle organizationGO:00069962270.026
Worm
nuclear migrationGO:000709730.026
multi organism processGO:00517041340.026
Fly
regulation of wnt signaling pathwayGO:0030111530.025
positive regulation of notch signaling pathwayGO:004574730.025
negative regulation of response to stimulusGO:00485851040.025
response to stressGO:00069502630.025
cognitionGO:005089010.025
positive regulation of gtp catabolic processGO:003312610.025
cartilage morphogenesisGO:0060536130.025
purine ribonucleoside monophosphate catabolic processGO:000916940.025
Worm
endochondral bone morphogenesisGO:006035080.024
cellular component disassemblyGO:002241110.024
carbohydrate derivative metabolic processGO:1901135610.024
Worm
regulation of dna replicationGO:000627530.024
regulation of gtp catabolic processGO:003312420.024
response to woundingGO:00096111160.024
peptidyl serine modificationGO:001820920.024
regulation of organ growthGO:004662030.024
appendage developmentGO:0048736800.024
Fly
stem cell developmentGO:0048864820.024
wnt signaling pathwayGO:0016055800.024
carboxylic acid metabolic processGO:0019752220.023
cellular protein metabolic processGO:00442671290.023
meiotic cell cycle processGO:190304630.023
regulation of extrinsic apoptotic signaling pathwayGO:200123630.023
neuronal action potentialGO:0019228180.023
regulation of cell projection assemblyGO:006049140.023
gland developmentGO:00487321430.023
regulation of carbohydrate metabolic processGO:000610940.023
hemopoiesisGO:00300971830.023
response to endogenous stimulusGO:0009719830.023
generation of neuronsGO:00486993850.023
regulation of cell morphogenesis involved in differentiationGO:0010769380.023
cellular aromatic compound metabolic processGO:00067252950.023
Worm
septum transversum developmentGO:000334340.023
cellular amine metabolic processGO:004410620.023
regulation of rna biosynthetic processGO:20011412130.022
cellular response to organic substanceGO:00713101050.022
mesenchymal cell developmentGO:0014031780.022
response to other organismGO:0051707970.022
spermatid differentiationGO:004851520.022
Fly
positive regulation of cytokine productionGO:000181920.022
collagen biosynthetic processGO:003296420.022
regulation of nucleotide catabolic processGO:003081120.022
regulation of protein complex disassemblyGO:004324410.022
hepaticobiliary system developmentGO:0061008980.021
embryonic skeletal system developmentGO:0048706970.021
positive regulation of protein complex assemblyGO:003133420.021
striated muscle tissue developmentGO:00147061100.021
single organism biosynthetic processGO:0044711710.021
energy reserve metabolic processGO:000611220.021
cellular biosynthetic processGO:00442492860.021
homeostatic processGO:00425921420.021
synaptic vesicle localizationGO:009747910.021
endoderm formationGO:0001706290.021
embryonic heart tube morphogenesisGO:00031431080.020
extracellular matrix organizationGO:0030198270.020
regulation of epithelial cell proliferationGO:005067830.020
positive regulation of stem cell proliferationGO:200064810.020
multicellular organismal signalingGO:0035637220.020
positive regulation of transcription dna templatedGO:0045893570.020
cortical cytoskeleton organizationGO:003086510.020
anterior posterior pattern specificationGO:00099521520.020
cell projection organizationGO:00300302840.020
canonical wnt signaling pathwayGO:0060070480.020
establishment of protein localization to plasma membraneGO:009000210.020
positive regulation of protein polymerizationGO:003227320.020
positive regulation of rna biosynthetic processGO:1902680570.020
regulation of gtpase activityGO:004308720.020
cellular protein localizationGO:0034613200.020
cytokinesisGO:000091030.020
regulation of stem cell proliferationGO:007209120.020
peptidyl threonine phosphorylationGO:001810710.019
spermatid developmentGO:000728620.019
Fly
sensory perceptionGO:0007600390.019
response to organic cyclic compoundGO:0014070510.019
oxidation reduction processGO:0055114410.019
regulation of tube sizeGO:003515020.019
regulation of macromolecule biosynthetic processGO:00105562250.019
nucleoside monophosphate catabolic processGO:000912540.019
Worm
response to oxygen levelsGO:0070482250.019
small gtpase mediated signal transductionGO:000726480.019
protein complex biogenesisGO:0070271300.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
positive regulation of cellular biosynthetic processGO:0031328680.018
positive regulation of nucleotide catabolic processGO:003081310.018
regulation of cellular ketone metabolic processGO:001056570.018
cortical actin cytoskeleton organizationGO:003086610.018
organic acid metabolic processGO:0006082310.018
nucleoside phosphate metabolic processGO:0006753280.018
Worm
membrane invaginationGO:001032410.018
phagocytosis engulfmentGO:000691110.018
lateral inhibitionGO:004633110.018
internal peptidyl lysine acetylationGO:001839320.018
transcription from rna polymerase ii promoterGO:0006366800.018
glucose importGO:004632320.018
cellular response to starvationGO:000926710.017
deathGO:00162651210.017
Worm
regulation of cellular carbohydrate metabolic processGO:001067540.017
striated muscle cell developmentGO:00550021080.017
positive regulation of cell adhesionGO:004578510.017
neuron projection morphogenesisGO:00488121610.017
cell cycle arrestGO:000705010.017
camera type eye developmentGO:00430102220.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
regulation of nucleoside metabolic processGO:000911820.017
purine nucleotide metabolic processGO:0006163270.017
Worm
camera type eye morphogenesisGO:00485931080.017
macromolecular complex disassemblyGO:003298410.017
trabecula formationGO:006034320.017
membrane fusionGO:006102520.016
cellular response to growth factor stimulusGO:0071363390.016
cell fate specificationGO:0001708680.016
regulation of intracellular signal transductionGO:1902531570.016
phosphorylationGO:0016310690.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
organic substance transportGO:0071702580.016
positive regulation of synapse assemblyGO:005196510.016
mesoderm developmentGO:0007498880.016
regulation of cellular amino acid metabolic processGO:000652100.016
membrane lipid biosynthetic processGO:004646720.016
convergent extension involved in gastrulationGO:0060027710.016
positive regulation of macromolecule biosynthetic processGO:0010557590.016
gastrulationGO:00073692080.016
axonogenesisGO:00074091520.016
endoderm developmentGO:0007492490.016
regulation of purine nucleotide catabolic processGO:003312120.016
embryonic digestive tract developmentGO:004856640.016
mitochondrion organizationGO:000700540.015
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of cellular component movementGO:0051270550.015
somatic stem cell maintenanceGO:003501910.015
positive regulation of gtpase activityGO:004354710.015
cell adhesion mediated by integrinGO:003362710.015
negative regulation of sequestering of calcium ionGO:005128340.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
positive regulation of leukocyte differentiationGO:190210710.015
response to bacteriumGO:0009617580.015
mesoderm morphogenesisGO:0048332510.015
negative regulation of multicellular organismal processGO:0051241690.015
defense response to fungusGO:005083220.015
embryonic pattern specificationGO:0009880440.015
ameboidal type cell migrationGO:00016671430.015
positive regulation of cell developmentGO:0010720250.015
response to biotic stimulusGO:0009607970.015
mesoderm formationGO:0001707430.015
signal transduction by phosphorylationGO:0023014180.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
positive regulation of immune effector processGO:000269930.015
lamellipodium organizationGO:009758110.015
cellular amide metabolic processGO:004360340.015
blood vessel morphogenesisGO:00485142160.015
stem cell divisionGO:001714510.015
regulation of cell migrationGO:0030334400.015
extrinsic apoptotic signaling pathwayGO:009719130.015
central nervous system developmentGO:00074173870.015
cellular response to fibroblast growth factor stimulusGO:0044344220.014
body morphogenesisGO:0010171160.014
positive regulation of cytoskeleton organizationGO:005149530.014
immune effector processGO:0002252230.014
interspecies interaction between organismsGO:004441940.014
nucleocytoplasmic transportGO:000691340.014
renal system processGO:0003014140.014
protein importGO:001703830.014
ear developmentGO:00435831270.014
cardiac atrium developmentGO:000323040.014
growth plate cartilage developmentGO:000341720.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.014
response to corticosteroidGO:003196010.014
regulation of protein transportGO:005122330.014
membrane raft organizationGO:003157910.014
purine nucleoside monophosphate catabolic processGO:000912840.014
Worm
immune system developmentGO:00025201910.014
liver developmentGO:0001889960.014
protein acylationGO:004354330.014
macromolecular complex assemblyGO:0065003350.014
negative regulation of defense responseGO:003134820.014
ion transportGO:00068111140.013
response to alkaloidGO:004327920.013
cellular protein catabolic processGO:004425740.013
regulation of cytokine productionGO:000181730.013
positive regulation of biosynthetic processGO:0009891680.013
negative regulation of cell differentiationGO:0045596460.013
regulation of protein catabolic processGO:004217610.013
action potentialGO:0001508190.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
regulation of cell cell adhesionGO:0022407130.013
nucleotide metabolic processGO:0009117280.013
Worm
regulation of transmembrane transporter activityGO:002289820.013
regulation of cell matrix adhesionGO:000195210.013
negative regulation of nuclear divisionGO:005178430.013
regulation of rna metabolic processGO:00512522240.013
inner ear morphogenesisGO:0042472630.013
cellular amino acid metabolic processGO:000652070.013
oxoacid metabolic processGO:0043436310.013
regulation of cell deathGO:00109411030.013
Worm
organophosphate metabolic processGO:0019637370.013
Worm
determination of bilateral symmetryGO:00098552040.013
ras protein signal transductionGO:000726570.013
synaptic growth at neuromuscular junctionGO:005112420.013
erk1 and erk2 cascadeGO:007037140.013
response to xenobiotic stimulusGO:0009410450.013
axon ensheathment in central nervous systemGO:003229120.013
neural crest cell differentiationGO:0014033720.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
regulation of ras gtpase activityGO:003231820.013

ehd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.181
musculoskeletal system diseaseDOID:1700.050
bone diseaseDOID:008000100.050
connective tissue diseaseDOID:6500.050
nervous system diseaseDOID:86300.049
charcot marie tooth disease type 4DOID:005054100.043
neuromuscular diseaseDOID:44000.043
neuropathyDOID:87000.043
charcot marie tooth diseaseDOID:1059500.043
immune system diseaseDOID:291400.037
bone development diseaseDOID:008000600.025
disease of cellular proliferationDOID:1456600.017
disease of metabolismDOID:001466700.016
cancerDOID:16200.015
organ system cancerDOID:005068600.014