Danio rerio

0 known processes

she

Src homology 2 domain containing E

she biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
stem cell proliferationGO:007208940.301
cellular component movementGO:00069283350.271
tube morphogenesisGO:00352393490.254
extrinsic apoptotic signaling pathwayGO:009719130.167
organelle organizationGO:00069962270.152
ameboidal type cell migrationGO:00016671430.132
sprouting angiogenesisGO:0002040530.130
blood vessel developmentGO:00015682460.130
nephron epithelium morphogenesisGO:007208810.127
lymph vessel developmentGO:0001945270.126
agingGO:000756820.118
regulation of cell substrate adhesionGO:001081010.112
embryonic organ morphogenesisGO:00485622740.102
blood vessel morphogenesisGO:00485142160.101
regulation of biological qualityGO:00650082630.100
cell migrationGO:00164772370.097
protein localization to nucleusGO:003450430.096
pigmentationGO:0043473850.095
lymph vessel morphogenesisGO:0036303250.090
cell motilityGO:00488702440.088
signal transductionGO:00071654550.083
nephron tubule morphogenesisGO:007207810.081
localization of cellGO:00516742440.080
regulation of multicellular organism growthGO:004001440.079
locomotionGO:00400113130.078
response to copper ionGO:0046688130.078
sensory organ developmentGO:00074233930.076
gastrulationGO:00073692080.076
lymphangiogenesisGO:0001946250.075
regulation of multicellular organismal processGO:00512392770.069
regulation of developmental processGO:00507932470.066
regulation of signalingGO:00230512350.066
regulation of cell matrix adhesionGO:000195210.064
embryonic organ developmentGO:00485683810.064
brain developmentGO:00074202930.063
regulation of neurogenesisGO:0050767870.062
vasculature developmentGO:00019442780.061
positive regulation of catabolic processGO:000989640.060
multi organism cellular processGO:004476420.060
morphogenesis of an epitheliumGO:00020093330.059
microtubule based movementGO:0007018330.058
cell matrix adhesionGO:000716040.058
guanosine containing compound catabolic processGO:190106920.054
symbiosis encompassing mutualism through parasitismGO:004440340.054
cell part morphogenesisGO:00329902460.054
morphogenesis of a branching epitheliumGO:0061138160.053
digestive tract developmentGO:00485652650.051
regulation of synaptic plasticityGO:004816710.051
cellular amine metabolic processGO:004410620.050
autophagyGO:000691440.049
epithelial tube morphogenesisGO:00605621480.048
guanosine containing compound metabolic processGO:190106840.047
regulation of multicellular organismal developmentGO:20000262230.047
canonical wnt signaling pathwayGO:0060070480.047
cellular response to starvationGO:000926710.046
regulation of cell shapeGO:000836010.046
synaptic vesicle localizationGO:009747910.045
positive regulation of cellular catabolic processGO:003133130.044
response to chemicalGO:00422213200.044
cell substrate junction assemblyGO:000704420.044
regulation of cellular amino acid metabolic processGO:000652100.043
regulation of extrinsic apoptotic signaling pathwayGO:200123630.042
skeletal muscle tissue developmentGO:0007519670.042
exocytosisGO:000688710.042
skeletal muscle organ developmentGO:0060538780.042
negative regulation of cellular processGO:00485232830.040
myotube differentiationGO:0014902450.040
organic acid metabolic processGO:0006082310.040
amino acid transportGO:000686520.039
nephron morphogenesisGO:007202820.039
defense responseGO:0006952470.038
dicarboxylic acid transportGO:000683510.038
single organism organelle organizationGO:19025891990.038
negative regulation of chemotaxisGO:005092240.038
melanocyte differentiationGO:0030318260.037
ear morphogenesisGO:0042471640.037
connective tissue developmentGO:0061448990.037
skeletal system developmentGO:00015011810.037
cell surface receptor signaling pathwayGO:00071663250.036
cell projection morphogenesisGO:00488582440.036
regulation of stem cell proliferationGO:007209120.036
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.036
neuroblast proliferationGO:000740520.036
cell substrate adherens junction assemblyGO:000704510.036
gtp catabolic processGO:000618420.036
sensory organ morphogenesisGO:00905962000.035
positive regulation of mesenchymal cell proliferationGO:000205310.035
branching morphogenesis of an epithelial tubeGO:0048754150.035
response to alkaloidGO:004327920.035
positive regulation of nucleoside metabolic processGO:004597910.034
regulation of cell differentiationGO:00455951420.034
regulation of ion transmembrane transporter activityGO:003241220.033
establishment of protein localization to organelleGO:007259440.033
digestive tract morphogenesisGO:00485462310.033
regulation of anatomical structure morphogenesisGO:00226031300.033
regulation of signal transductionGO:00099662250.033
actin filament based processGO:0030029640.032
female gonad developmentGO:000858540.032
signal transduction in absence of ligandGO:003803410.032
regulation of purine nucleotide catabolic processGO:003312120.031
single organism localizationGO:19025782250.031
negative regulation of tor signalingGO:003200720.031
gtp metabolic processGO:004603940.031
organelle transport along microtubuleGO:007238410.031
venous blood vessel developmentGO:006084190.031
establishment of localizationGO:00512342440.031
amine metabolic processGO:000930820.030
single organism transportGO:00447652060.030
neuron projection morphogenesisGO:00488121610.030
cell morphogenesisGO:00009022890.030
skeletal system morphogenesisGO:00487051020.030
response to transition metal nanoparticleGO:1990267280.030
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.030
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.030
regulation of cellular metabolic processGO:00313233200.030
negative regulation of cytoplasmic transportGO:190365020.029
regulation of skeletal muscle tissue developmentGO:004864140.029
ear developmentGO:00435831270.029
developmental pigmentationGO:0048066480.028
central nervous system developmentGO:00074173870.028
post golgi vesicle mediated transportGO:000689210.028
positive regulation of cell cycleGO:004578730.028
peptidyl serine phosphorylationGO:001810510.028
nitrogen compound metabolic processGO:00068073190.028
response to woundingGO:00096111160.028
negative regulation of angiogenesisGO:001652570.028
regulation of response to stimulusGO:00485832690.028
chordate embryonic developmentGO:00430092710.028
muscle cell migrationGO:001481240.027
nuclear importGO:005117030.027
cognitionGO:005089010.027
positive regulation of cellular component biogenesisGO:004408930.027
positive regulation of cellular amine metabolic processGO:003324000.027
positive regulation of gtp catabolic processGO:003312610.027
adherens junction organizationGO:003433240.027
cellular protein modification processGO:00064641000.027
cellular component morphogenesisGO:00329893360.027
regulation of cell communicationGO:00106462320.027
anatomical structure homeostasisGO:0060249360.027
cytoskeleton organizationGO:0007010960.026
positive regulation of gtpase activityGO:004354710.026
positive regulation of purine nucleotide catabolic processGO:003312310.026
negative regulation of intracellular transportGO:003238730.025
regulation of nucleotide catabolic processGO:003081120.025
peptidyl serine modificationGO:001820920.025
regulation of dendrite developmentGO:005077330.025
cellular response to extracellular stimulusGO:003166820.025
single organism nuclear importGO:190259330.025
mesenchymal cell differentiationGO:0048762870.025
cell morphogenesis involved in differentiationGO:00009041950.025
positive regulation of nucleotide catabolic processGO:003081310.025
protein import into nucleusGO:000660630.025
myeloid leukocyte migrationGO:0097529120.025
regulation of endothelial cell proliferationGO:000193610.025
response to glucocorticoidGO:005138410.025
neural crest cell differentiationGO:0014033720.024
epiboly involved in gastrulation with mouth forming secondGO:0055113350.024
protein importGO:001703830.024
regulation of tor signalingGO:003200670.024
regulation of vasculature developmentGO:1901342330.024
negative regulation of protein transportGO:005122430.024
retina development in camera type eyeGO:00600411460.024
positive regulation of endothelial cell proliferationGO:000193810.024
cell projection assemblyGO:0030031640.024
regulation of protein targetingGO:190353320.023
organonitrogen compound metabolic processGO:1901564740.023
ovarian follicle developmentGO:000154120.023
viral processGO:001603210.023
positive regulation of muscle tissue developmentGO:190186310.023
leukocyte chemotaxisGO:0030595120.023
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.023
regulation of neural precursor cell proliferationGO:200017730.023
cell substrate adhesionGO:003158940.022
mechanosensory behaviorGO:000763820.022
regulation of autophagyGO:001050630.022
negative regulation of biological processGO:00485193040.022
response to metal ionGO:0010038340.022
positive regulation of erk1 and erk2 cascadeGO:007037420.022
microtubule based transportGO:0010970100.022
regulation of dna replicationGO:000627530.022
positive regulation of epithelial cell migrationGO:001063420.022
positive regulation of developmental processGO:0051094500.022
microtubule based processGO:0007017600.021
heterocycle metabolic processGO:00464832900.021
regulation of neuron projection developmentGO:0010975400.021
regulation of cell developmentGO:00602841000.021
regulation of protein bindingGO:004339330.021
regulation of chemotaxisGO:0050920180.021
regulation of dendrite morphogenesisGO:004881430.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
regulation of melanocyte differentiationGO:004563420.021
regulation of rna metabolic processGO:00512522240.021
head developmentGO:00603223030.020
regulation of carbohydrate metabolic processGO:000610940.020
mitochondrial transportGO:000683920.020
ras protein signal transductionGO:000726570.020
urogenital system developmentGO:0001655970.020
positive regulation of positive chemotaxisGO:005092740.020
epithelial cell differentiationGO:00308551160.020
regulation of cell morphogenesisGO:0022604420.020
internal protein amino acid acetylationGO:000647520.020
negative regulation of response to stimulusGO:00485851040.020
g2 m transition of mitotic cell cycleGO:000008640.020
neural crest cell migrationGO:0001755420.020
phagocytosisGO:000690930.020
regulation of cytoplasmic transportGO:190364940.020
regulation of gtpase activityGO:004308720.020
positive regulation of secretion by cellGO:190353210.020
multicellular organism growthGO:003526440.020
response to amino acidGO:004320020.020
pigment cell differentiationGO:0050931380.020
regulation of protein transportGO:005122330.020
regulation of bindingGO:005109830.019
protein targeting to nucleusGO:004474430.019
regulation of cell projection organizationGO:0031344440.019
smooth muscle contractionGO:000693920.019
phosphatidylinositol mediated signalingGO:004801520.019
regulation of gtp catabolic processGO:003312420.019
endodermal cell fate determinationGO:000749320.019
cellular macromolecule biosynthetic processGO:00346452240.019
regulation of protein ubiquitinationGO:003139630.019
protein polyubiquitinationGO:000020940.019
positive regulation of cell matrix adhesionGO:000195410.019
lateral line system developmentGO:0048925760.019
cellular response to light stimulusGO:007148240.018
cellular localizationGO:0051641970.018
negative regulation of signal transductionGO:0009968940.018
transportGO:00068102200.018
cell projection organizationGO:00300302840.018
regulation of epithelial cell proliferationGO:005067830.018
granulocyte chemotaxisGO:0071621110.018
actin filament organizationGO:0007015150.018
patterning of blood vesselsGO:0001569150.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
regulation of cell morphogenesis involved in differentiationGO:0010769380.018
heterocycle biosynthetic processGO:00181302150.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
chemotaxisGO:00069351040.018
phagocytosis engulfmentGO:000691110.018
response to corticosteroidGO:003196010.018
heart loopingGO:0001947940.018
regulation of cellular component organizationGO:0051128860.018
negative regulation of cell communicationGO:0010648960.018
regulation of nucleoside metabolic processGO:000911820.018
golgi vesicle transportGO:004819330.018
regulation of axonogenesisGO:0050770320.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
embryo development ending in birth or egg hatchingGO:00097922710.017
phosphate containing compound metabolic processGO:00067961080.017
nucleocytoplasmic transportGO:000691340.017
positive regulation of biological processGO:00485182530.017
mesenchyme developmentGO:00604851270.017
regulation of protein import into nucleusGO:004230620.017
endothelial cell proliferationGO:0001935110.017
synaptic growth at neuromuscular junctionGO:005112420.017
macrophage chemotaxisGO:004824630.017
negative regulation of protein localization to nucleusGO:190018120.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
protein metabolic processGO:00195381830.017
lipid catabolic processGO:001604240.017
response to drugGO:004249330.017
negative regulation of blood circulationGO:190352320.017
secondary metabolic processGO:001974830.016
regulation of blood vessel sizeGO:005088020.016
synaptic vesicle endocytosisGO:004848810.016
positive regulation of secretionGO:005104710.016
angiogenesisGO:00015251580.016
regulation of rho protein signal transductionGO:003502320.016
intracellular signal transductionGO:0035556850.016
organelle localizationGO:0051640490.016
cortical cytoskeleton organizationGO:003086510.016
convergent extensionGO:00600261180.016
cytokinesisGO:000091030.016
positive regulation of camp metabolic processGO:003081620.016
negative regulation of epithelial cell proliferationGO:005068010.016
embryonic skeletal system developmentGO:0048706970.016
cilium organizationGO:0044782710.016
regulation of positive chemotaxisGO:005092640.016
regulation of neuron differentiationGO:0045664560.016
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.016
wound healingGO:0042060900.016
cellular protein metabolic processGO:00442671290.016
negative regulation of protein import into nucleusGO:004230820.016
cellular response to nutrient levelsGO:003166920.016
sleepGO:003043110.015
negative regulation of protein complex assemblyGO:003133310.015
organic cyclic compound metabolic processGO:19013603010.015
cellular response to hypoxiaGO:007145610.015
cellular response to oxygen levelsGO:007145310.015
system processGO:00030081850.015
developmental growthGO:00485891660.015
organic substance biosynthetic processGO:19015762890.015
regulation of exocytosisGO:001715710.015
mesenchymal cell developmentGO:0014031780.015
female sex differentiationGO:004666040.015
regulation of mesenchymal cell proliferationGO:001046410.015
positive regulation of immune effector processGO:000269930.015
nuclear transportGO:005116940.015
positive regulation of cytoskeleton organizationGO:005149530.015
positive regulation of muscle cell differentiationGO:005114910.015
hair cell differentiationGO:0035315320.015
response to carbohydrateGO:000974330.015
response to external stimulusGO:00096052640.015
regulation of transmembrane transporter activityGO:002289820.015
anterior posterior pattern specificationGO:00099521520.015
endomembrane system organizationGO:0010256130.015
tor signalingGO:003192970.014
neural crest cell developmentGO:0014032620.014
response to abiotic stimulusGO:00096281220.014
heart developmentGO:00075073130.014
positive regulation of cell adhesionGO:004578510.014
positive regulation of molecular functionGO:0044093330.014
carbohydrate derivative biosynthetic processGO:1901137430.014
regulation of synapse organizationGO:005080730.014
cartilage developmentGO:0051216960.014
wnt signaling pathwayGO:0016055800.014
axonogenesisGO:00074091520.014
establishment of synaptic vesicle localizationGO:009748010.014
regulation of protein depolymerizationGO:190187910.014
regulation of cell activationGO:005086510.014
small gtpase mediated signal transductionGO:000726480.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
rna metabolic processGO:00160702190.014
regulation of tube sizeGO:003515020.014
regulation of protein complex assemblyGO:004325430.014
stem cell maintenanceGO:001982740.014
renal tubule morphogenesisGO:006133310.014
regulation of canonical wnt signaling pathwayGO:0060828340.014
interspecies interaction between organismsGO:004441940.014
negative regulation of axon extension involved in axon guidanceGO:004884310.014
generation of neuronsGO:00486993850.014
liver developmentGO:0001889960.014
regulation of biomineral tissue developmentGO:007016720.014
larval developmentGO:000216420.014
skin developmentGO:0043588540.014
centrosome organizationGO:005129710.014
regulation of nitrogen compound metabolic processGO:00511712510.014
regulation of transporter activityGO:003240920.014
regulation of vasculogenesisGO:200121210.014
ribose phosphate metabolic processGO:0019693270.014
nucleobase containing compound metabolic processGO:00061392740.014
negative regulation of synapse assemblyGO:005196420.014
cellular ketone metabolic processGO:0042180110.013
proteasomal protein catabolic processGO:001049820.013
cellular nitrogen compound metabolic processGO:00346412900.013
ribonucleotide metabolic processGO:0009259270.013
cell migration involved in gastrulationGO:0042074790.013
positive regulation of transportGO:005105020.013
striated muscle tissue developmentGO:00147061100.013
stem cell divisionGO:001714510.013
regulation of cell projection assemblyGO:006049140.013
tissue homeostasisGO:0001894250.013
regulation of cell deathGO:00109411030.013
adherens junction assemblyGO:003433310.013
protein dephosphorylationGO:000647030.013
regulation of cellular amine metabolic processGO:003323800.013
negative regulation of intracellular protein transportGO:009031730.013
cellular component biogenesisGO:00440851780.013
neuron developmentGO:00486662620.013
establishment of organelle localizationGO:0051656450.013
epithelium migrationGO:0090132250.013
transmission of nerve impulseGO:0019226190.013
eye developmentGO:00016542770.013
regionalizationGO:00030022740.013
protein acetylationGO:000647320.013
ovulation cycle processGO:002260220.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.013
trabecula morphogenesisGO:006138320.013
regulation of nucleotide metabolic processGO:0006140170.013
gland developmentGO:00487321430.013
regulation of cell motilityGO:2000145460.013
regulation of cellular component movementGO:0051270550.013
cellular macromolecule metabolic processGO:00442603910.013
negative regulation of signalingGO:0023057960.013
regulation of intracellular protein transportGO:003315730.013
regulation of apoptotic processGO:0042981980.013
negative regulation of nucleocytoplasmic transportGO:004682320.012
sensory perception of smellGO:000760820.012
regulation of cellular component sizeGO:0032535300.012
regulation of protein catabolic processGO:004217610.012
primary neural tube formationGO:001402010.012
neutrophil migrationGO:1990266100.012
regulation of oligodendrocyte differentiationGO:004871310.012
synaptic vesicle transportGO:004848910.012
phosphorylationGO:0016310690.012
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.012
cellular response to chemical stimulusGO:00708871570.012
response to biotic stimulusGO:0009607970.012
protein modification processGO:00362111000.012
b cell activationGO:004211320.012
axon developmentGO:00615641660.012
positive regulation of epithelial cell differentiationGO:003085820.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
negative regulation of protein phosphorylationGO:000193340.012
actin cytoskeleton organizationGO:0030036630.012
regulation of programmed cell deathGO:00430671010.012
collateral sprouting in absence of injuryGO:004866940.012
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.012
pyruvate metabolic processGO:000609010.012
negative chemotaxisGO:005091910.012
convergent extension involved in gastrulationGO:0060027710.012
regulation of endothelial cell differentiationGO:004560130.012
regulation of actin filament based processGO:003297090.012
central nervous system myelinationGO:002201020.012
odontogenesis of dentin containing toothGO:004247510.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.012
embryonic skeletal system morphogenesisGO:0048704930.012
negative regulation of secretionGO:005104820.012
macromolecule biosynthetic processGO:00090592270.011
positive regulation of blood circulationGO:190352420.011
notch signaling pathwayGO:0007219350.011
morphogenesis of a branching structureGO:0001763210.011
regulation of myotube differentiationGO:001083020.011
ribonucleoside triphosphate biosynthetic processGO:000920120.011
regulation of bone mineralizationGO:003050020.011
b cell differentiationGO:003018310.011
regulation of cellular response to growth factor stimulusGO:0090287350.011
dna templated transcription elongationGO:000635430.011
regulation of localizationGO:00328791040.011
response to ketoneGO:190165410.011
carboxylic acid metabolic processGO:0019752220.011
regulation of blood pressureGO:000821710.011
ubiquitin dependent protein catabolic processGO:000651130.011
neurological system processGO:0050877620.011
neuron projection extensionGO:1990138450.011
regulation of nervous system developmentGO:0051960900.011
positive regulation of cell substrate adhesionGO:001081110.011
regulation of phosphate metabolic processGO:0019220430.011
apoptotic processGO:00069151160.011
response to organic substanceGO:00100331530.011
regulation of cell migration involved in sprouting angiogenesisGO:009004930.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
regulation of cellular ketone metabolic processGO:001056570.011
carbohydrate derivative metabolic processGO:1901135610.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
myoblast fusionGO:0007520100.011
ovulation cycleGO:004269820.011
chemosensory behaviorGO:000763510.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of actin cytoskeleton organizationGO:003295680.011
regulation of ras gtpase activityGO:003231820.011
negative regulation of multicellular organismal processGO:0051241690.011
positive regulation of leukocyte differentiationGO:190210710.011
development of primary female sexual characteristicsGO:004654540.011
cytoskeleton dependent intracellular transportGO:0030705100.011
cell cycle g2 m phase transitionGO:004483940.011
biosynthetic processGO:00090582940.011
adult behaviorGO:003053420.011
regulation of anatomical structure sizeGO:0090066330.011
peptidyl lysine acetylationGO:001839420.011
behaviorGO:0007610740.010
regulation of extent of cell growthGO:0061387290.010
mononuclear cell proliferationGO:003294310.010
antimicrobial humoral responseGO:001973020.010
cellular response to external stimulusGO:007149620.010
meiotic nuclear divisionGO:000712640.010
sensory system developmentGO:0048880760.010
regulation of lymphangiogenesisGO:190149040.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
startle responseGO:000196440.010
positive regulation of epithelial cell proliferationGO:005067910.010
protein complex subunit organizationGO:0071822460.010
epithelial cell proliferationGO:0050673170.010
muscle tissue developmentGO:00605371100.010
cellular carbohydrate metabolic processGO:004426240.010
regulation of behaviorGO:0050795240.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
positive regulation of striated muscle tissue developmentGO:004584410.010
lymphocyte proliferationGO:004665110.010
positive regulation of exocytosisGO:004592110.010
positive regulation of cellular metabolic processGO:0031325940.010
maintenance of locationGO:005123540.010
cellular transition metal ion homeostasisGO:004691630.010
protein phosphorylationGO:0006468470.010
inner ear developmentGO:00488391260.010

she disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.014
organ system cancerDOID:005068600.013
sensory system diseaseDOID:005015500.013