Danio rerio

0 known processes

tbck

TBC1 domain containing kinase

(Aliases: wu:fc74a10,im:7138354,zgc:158710)

tbck biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.115
agingGO:000756820.061
meiotic nuclear divisionGO:000712640.047
maintenance of locationGO:005123540.039
proteolysis involved in cellular protein catabolic processGO:005160330.037
cellular protein catabolic processGO:004425740.037
positive regulation of transportGO:005105020.037
protein acetylationGO:000647320.036
phagocytosisGO:000690930.036
proteasomal protein catabolic processGO:001049820.036
regulation of meiotic cell cycleGO:005144510.035
establishment of protein localization to organelleGO:007259440.034
multicellular organism growthGO:003526440.032
signal transductionGO:00071654550.032
amine metabolic processGO:000930820.032
cellular amine metabolic processGO:004410620.031
positive regulation of cellular catabolic processGO:003133130.030
nucleocytoplasmic transportGO:000691340.030
negative regulation of protein phosphorylationGO:000193340.030
positive regulation of catabolic processGO:000989640.030
nuclear transportGO:005116940.029
modification dependent macromolecule catabolic processGO:004363230.029
modification dependent protein catabolic processGO:001994130.029
lipid storageGO:001991510.029
ubiquitin dependent protein catabolic processGO:000651130.029
regulation of establishment of protein localizationGO:007020140.029
autophagyGO:000691440.028
regulation of mrna splicing via spliceosomeGO:004802430.028
cellular macromolecule metabolic processGO:00442603910.028
regulation of protein transportGO:005122330.028
regulation of cytokine productionGO:000181730.027
mitochondrion organizationGO:000700540.027
protein acylationGO:004354330.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
cellular response to external stimulusGO:007149620.027
nitrogen compound metabolic processGO:00068073190.027
regulation of mrna processingGO:005068430.026
regulation of multicellular organism growthGO:004001440.026
cell surface receptor signaling pathwayGO:00071663250.026
regulation of cellular amine metabolic processGO:003323800.026
protein importGO:001703830.026
regulation of protein catabolic processGO:004217610.026
positive regulation of cellular component biogenesisGO:004408930.026
cellular nitrogen compound metabolic processGO:00346412900.025
gtp metabolic processGO:004603940.025
peptidyl lysine acetylationGO:001839420.025
gene expressionGO:00104672520.025
meiotic cell cycle processGO:190304630.025
guanosine containing compound metabolic processGO:190106840.025
biosynthetic processGO:00090582940.025
positive regulation of cell cycleGO:004578730.024
regulation of protein complex assemblyGO:004325430.024
gtp catabolic processGO:000618420.024
negative regulation of biological processGO:00485193040.024
internal protein amino acid acetylationGO:000647520.024
regulation of cellular amino acid metabolic processGO:000652100.024
organic cyclic compound metabolic processGO:19013603010.024
regulation of metabolic processGO:00192223590.024
single organism nuclear importGO:190259330.023
cellular aromatic compound metabolic processGO:00067252950.023
stem cell maintenanceGO:001982740.023
guanosine containing compound catabolic processGO:190106920.023
protein import into nucleusGO:000660630.023
internal peptidyl lysine acetylationGO:001839320.023
nuclear importGO:005117030.023
immune system processGO:00023762410.023
organic substance biosynthetic processGO:19015762890.023
centrosome organizationGO:005129710.023
cellular biosynthetic processGO:00442492860.023
regulation of bindingGO:005109830.023
protein localization to nucleusGO:003450430.022
cellular response to extracellular stimulusGO:003166820.022
rna metabolic processGO:00160702190.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
heterocycle metabolic processGO:00464832900.022
endosomal transportGO:001619720.022
response to drugGO:004249330.022
organonitrogen compound metabolic processGO:1901564740.022
cytokinesisGO:000091030.022
central nervous system developmentGO:00074173870.022
cellular ketone metabolic processGO:0042180110.022
cellular response to nutrient levelsGO:003166920.022
cellular amino acid metabolic processGO:000652070.021
regulation of cell shapeGO:000836010.021
nucleobase containing compound metabolic processGO:00061392740.021
organelle organizationGO:00069962270.021
single organism metabolic processGO:00447102170.021
rna localizationGO:000640340.021
tissue remodelingGO:004877140.021
protein metabolic processGO:00195381830.021
regulation of cytoplasmic transportGO:190364940.021
nucleic acid metabolic processGO:00903042440.021
cellular component disassemblyGO:002241110.021
membrane fusionGO:006102520.021
regulation of cellular ketone metabolic processGO:001056570.021
protein targeting to nucleusGO:004474430.020
regulation of protein localization to nucleusGO:190018020.020
regulation of biosynthetic processGO:00098892500.020
locomotor rhythmGO:004547530.020
regulation of nitrogen compound metabolic processGO:00511712510.020
regulation of intracellular protein transportGO:003315730.020
phagocytosis engulfmentGO:000691110.020
positive regulation of cellular amine metabolic processGO:003324000.020
regulation of reproductive processGO:200024140.020
organic cyclic compound biosynthetic processGO:19013622230.020
regulation of cellular metabolic processGO:00313233200.020
regulation of primary metabolic processGO:00800903110.020
regulation of nucleocytoplasmic transportGO:004682220.020
regulation of gene expressionGO:00104682650.020
regulation of protein ubiquitinationGO:003139630.020
regulation of cell communicationGO:00106462320.020
locomotionGO:00400113130.020
stem cell proliferationGO:007208940.020
regulation of macromolecule metabolic processGO:00602553170.019
cellular response to starvationGO:000926710.019
regulation of protein import into nucleusGO:004230620.019
regulation of protein targetingGO:190353320.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
negative regulation of cellular processGO:00485232830.019
protein localization to plasma membraneGO:007265910.019
nucleic acid templated transcriptionGO:00976591810.019
positive regulation of translationGO:004572710.019
regulation of neural precursor cell proliferationGO:200017730.019
cellular macromolecule biosynthetic processGO:00346452240.019
response to uvGO:000941130.019
establishment of localizationGO:00512342440.019
positive regulation of cytokine productionGO:000181920.019
immune system developmentGO:00025201910.019
positive regulation of secretionGO:005104710.018
single organism membrane fusionGO:004480120.018
oxoacid metabolic processGO:0043436310.018
membrane invaginationGO:001032410.018
sensory organ developmentGO:00074233930.018
organic acid metabolic processGO:0006082310.018
neuroblast proliferationGO:000740520.018
response to external stimulusGO:00096052640.018
spermatid developmentGO:000728620.018
negative regulation of kinase activityGO:003367340.018
regulation of nucleoside metabolic processGO:000911820.018
cytoskeleton dependent cytokinesisGO:006164030.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of gtp catabolic processGO:003312420.018
cellular respirationGO:004533330.018
small molecule metabolic processGO:0044281770.018
response to stressGO:00069502630.018
regulation of nucleotide catabolic processGO:003081120.018
cellular component biogenesisGO:00440851780.018
negative regulation of protein kinase activityGO:000646940.018
carboxylic acid metabolic processGO:0019752220.018
regulation of biological qualityGO:00650082630.018
tube morphogenesisGO:00352393490.018
cellular protein metabolic processGO:00442671290.018
positive regulation of stress activated mapk cascadeGO:003287430.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of signalingGO:00230512350.017
response to monosaccharideGO:003428430.017
positive regulation of secretion by cellGO:190353210.017
cell projection organizationGO:00300302840.017
response to chemicalGO:00422213200.017
regulation of multicellular organismal processGO:00512392770.017
regulation of cell activationGO:005086510.017
microtubule organizing center organizationGO:003102310.017
protein secretionGO:000930610.017
regulation of jak stat cascadeGO:004642530.017
cellular carbohydrate metabolic processGO:004426240.017
regionalizationGO:00030022740.017
single organism localizationGO:19025782250.017
cellular component assemblyGO:00226071700.017
response to topologically incorrect proteinGO:003596620.017
extrinsic apoptotic signaling pathwayGO:009719130.017
protein polymerizationGO:005125840.017
g1 s transition of mitotic cell cycleGO:000008210.017
nuclear exportGO:005116810.017
regulation of synapse organizationGO:005080730.017
cellular component morphogenesisGO:00329893360.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
response to carbohydrateGO:000974330.017
cellular response to radiationGO:007147840.017
cellular component movementGO:00069283350.017
single organism transportGO:00447652060.017
organelle fusionGO:004828430.017
cell morphogenesisGO:00009022890.016
glucose homeostasisGO:004259310.016
regulation of gtpase activityGO:004308720.016
development of primary female sexual characteristicsGO:004654540.016
regulation of response to stimulusGO:00485832690.016
female sex differentiationGO:004666040.016
sensory organ morphogenesisGO:00905962000.016
regulation of macromolecule biosynthetic processGO:00105562250.016
single organism organelle organizationGO:19025891990.016
alternative mrna splicing via spliceosomeGO:000038010.016
spermatid differentiationGO:004851520.016
mitotic dna integrity checkpointGO:004477440.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of synapse assemblyGO:005196420.016
neuron differentiationGO:00301823530.016
regulation of cellular biosynthetic processGO:00313262450.016
production of molecular mediator of immune responseGO:000244020.016
golgi vesicle transportGO:004819330.016
ribonucleoside monophosphate catabolic processGO:000915840.016
macromolecular complex disassemblyGO:003298410.016
negative regulation of catabolic processGO:000989530.016
regulation of synapse assemblyGO:005196330.016
cell matrix adhesionGO:000716040.015
regulation of inflammatory responseGO:005072720.015
rna biosynthetic processGO:00327741810.015
regulation of rna metabolic processGO:00512522240.015
positive regulation of gtp catabolic processGO:003312610.015
cell part morphogenesisGO:00329902460.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
leukocyte proliferationGO:007066110.015
transcription dna templatedGO:00063511810.015
protein polyubiquitinationGO:000020940.015
multi organism cellular processGO:004476420.015
nucleoside monophosphate catabolic processGO:000912540.015
regulation of erk1 and erk2 cascadeGO:007037240.015
regulation of transcription dna templatedGO:00063552130.015
peptidyl serine modificationGO:001820920.015
female gonad developmentGO:000858540.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
regulation of signal transductionGO:00099662250.015
digestive system developmentGO:00551232890.015
b cell activationGO:004211320.015
regulation of cellular protein catabolic processGO:190336210.015
compound eye developmentGO:004874920.015
protein complex disassemblyGO:004324110.015
macromolecule biosynthetic processGO:00090592270.015
cellular response to lipopolysaccharideGO:007122230.015
aromatic compound biosynthetic processGO:00194382170.015
morphogenesis of an epitheliumGO:00020093330.015
erk1 and erk2 cascadeGO:007037140.015
nucleobase containing compound biosynthetic processGO:00346542050.015
brain developmentGO:00074202930.015
cell substrate adhesionGO:003158940.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
positive regulation of protein complex assemblyGO:003133420.015
secondary metabolic processGO:001974830.015
dna templated transcription elongationGO:000635430.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
protein stabilizationGO:005082120.015
cellular amide metabolic processGO:004360340.015
positive regulation of cell activationGO:005086710.015
cellular response to biotic stimulusGO:007121630.015
negative regulation of protein complex assemblyGO:003133310.015
regulation of organelle assemblyGO:190211540.015
cellular response to light stimulusGO:007148240.015
embryo development ending in birth or egg hatchingGO:00097922710.015
regulation of developmental processGO:00507932470.014
eye developmentGO:00016542770.014
peptide transportGO:001583310.014
mitotic dna damage checkpointGO:004477340.014
meiotic chromosome segregationGO:004513230.014
carbohydrate homeostasisGO:003350010.014
i kappab kinase nf kappab signalingGO:000724940.014
adult behaviorGO:003053420.014
heterocycle biosynthetic processGO:00181302150.014
positive regulation of nucleoside metabolic processGO:004597910.014
negative regulation of nuclear divisionGO:005178430.014
somatic stem cell maintenanceGO:003501910.014
meiosis iGO:000712710.014
hemopoiesisGO:00300971830.014
positive regulation of map kinase activityGO:004340630.014
regulation of blood pressureGO:000821710.014
gastrulationGO:00073692080.014
macromolecule modificationGO:00434121110.014
atp catabolic processGO:000620040.014
actin polymerization or depolymerizationGO:000815420.014
specification of symmetryGO:00097992040.014
regulation of stem cell differentiationGO:200073640.014
positive regulation of cytoskeleton organizationGO:005149530.014
regulation of cell substrate adhesionGO:001081010.014
response to glucoseGO:000974930.014
peptidyl serine phosphorylationGO:001810510.014
cell migrationGO:00164772370.014
generation of neuronsGO:00486993850.014
regulation of stem cell proliferationGO:007209120.014
cognitionGO:005089010.014
nucleic acid transportGO:005065720.014
actin filament polymerizationGO:003004120.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
cellular response to molecule of bacterial originGO:007121930.014
cell projection morphogenesisGO:00488582440.014
rna transportGO:005065820.014
growthGO:00400071740.014
digestive tract developmentGO:00485652650.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
embryonic organ developmentGO:00485683810.013
protein dephosphorylationGO:000647030.013
positive regulation of gtpase activityGO:004354710.013
negative regulation of mapk cascadeGO:004340940.013
stem cell divisionGO:001714510.013
protein modification processGO:00362111000.013
heart developmentGO:00075073130.013
positive regulation of dna metabolic processGO:005105410.013
hormone transportGO:000991420.013
regulation of rho protein signal transductionGO:003502320.013
regulation of dna templated transcription elongationGO:003278430.013
cellular protein modification processGO:00064641000.013
vasculature developmentGO:00019442780.013
head developmentGO:00603223030.013
positive regulation of biological processGO:00485182530.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
adherens junction organizationGO:003433240.013
transportGO:00068102200.013
regulation of rna biosynthetic processGO:20011412130.013
sequestering of metal ionGO:005123830.013
exocytosisGO:000688710.013
system processGO:00030081850.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
antimicrobial humoral responseGO:001973020.013
regulation of reactive oxygen species metabolic processGO:200037720.013
localization of cellGO:00516742440.013
transcription from rna polymerase ii promoterGO:0006366800.013
interspecies interaction between organismsGO:004441940.013
cilium morphogenesisGO:0060271850.013
positive regulation of ras protein signal transductionGO:004657910.013
positive regulation of cell adhesionGO:004578510.013
mononuclear cell proliferationGO:003294310.013
negative regulation of cytokine productionGO:000181810.013
dorsal ventral pattern formationGO:00099531250.013
blood vessel developmentGO:00015682460.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
macroautophagyGO:001623610.012
post embryonic organ developmentGO:004856940.012
regulation of carbohydrate metabolic processGO:000610940.012
regulation of autophagyGO:001050630.012
digestive tract morphogenesisGO:00485462310.012
establishment of protein localization to plasma membraneGO:009000210.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
regulation of protein bindingGO:004339330.012
purine nucleoside monophosphate catabolic processGO:000912840.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of cellular processGO:00485222010.012
cell motilityGO:00488702440.012
response to nutrientGO:000758430.012
negative regulation of defense responseGO:003134820.012
establishment of rna localizationGO:005123630.012
double strand break repairGO:000630230.012
intracellular signal transductionGO:0035556850.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
embryonic organ morphogenesisGO:00485622740.012
regulation of muscle contractionGO:000693730.012
determination of bilateral symmetryGO:00098552040.012
response to hydrogen peroxideGO:004254230.012
mitotic cytokinesisGO:000028130.012
positive regulation of chromosome organizationGO:200125210.012
anterior posterior pattern specificationGO:00099521520.012
lamellipodium organizationGO:009758110.012
regulation of response to biotic stimulusGO:000283120.012
lymphocyte proliferationGO:004665110.012
synaptic growth at neuromuscular junctionGO:005112420.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
negative regulation of protein serine threonine kinase activityGO:007190120.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
lamellipodium assemblyGO:003003210.011
regulation of jun kinase activityGO:004350630.011
hormone secretionGO:004687920.011
positive regulation of immune effector processGO:000269930.011
negative regulation of cellular catabolic processGO:003133030.011
germ line stem cell maintenanceGO:003071820.011
regulation of protein polymerizationGO:003227120.011
translational initiationGO:000641330.011
mitochondrial transportGO:000683920.011
regulation of circadian rhythmGO:004275240.011
vacuolar transportGO:000703420.011
primary neural tube formationGO:001402010.011
g2 dna damage checkpointGO:003157230.011
convergent extensionGO:00600261180.011
cellular response to chemical stimulusGO:00708871570.011
cell substrate junction assemblyGO:000704420.011
multi organism processGO:00517041340.011
regulation of organ growthGO:004662030.011
cell agingGO:000756920.011
mitotic g2 m transition checkpointGO:004481830.011
positive regulation of notch signaling pathwayGO:004574730.011
regulation of synaptic plasticityGO:004816710.011
negative regulation of signal transductionGO:0009968940.011
regulation of multicellular organismal developmentGO:20000262230.011
spindle assemblyGO:005122520.011
mitotic cell cycle embryonicGO:004544820.011
positive regulation of jnk cascadeGO:004633030.011
negative regulation of sequestering of calcium ionGO:005128340.011
fertilizationGO:000956630.011
female meiotic divisionGO:000714320.011
cell deathGO:00082191210.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.011
negative regulation of protein transportGO:005122430.011
er to golgi vesicle mediated transportGO:000688810.011
response to hexoseGO:000974630.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
neuron developmentGO:00486662620.011
cytoplasm organizationGO:000702840.011
chordate embryonic developmentGO:00430092710.011
response to abiotic stimulusGO:00096281220.011
retina development in camera type eyeGO:00600411460.011
rna export from nucleusGO:000640510.011
regulation of protein complex disassemblyGO:004324410.011
tube closureGO:006060610.011
cellular response to topologically incorrect proteinGO:003596720.011
blood vessel morphogenesisGO:00485142160.011
developmental programmed cell deathGO:001062340.011
cytosolic calcium ion transportGO:006040130.011
atp synthesis coupled electron transportGO:004277310.011
regulation of microtubule cytoskeleton organizationGO:007050730.010
regulation of hormone secretionGO:004688320.010
regulation of production of molecular mediator of immune responseGO:000270010.010
negative regulation of translationGO:001714810.010
wnt signaling pathwayGO:0016055800.010
chemosensory behaviorGO:000763510.010
developmental growthGO:00485891660.010
g2 m transition of mitotic cell cycleGO:000008640.010
negative regulation of cell communicationGO:0010648960.010
axonogenesisGO:00074091520.010
activation of mapk activityGO:000018730.010
negative regulation of signalingGO:0023057960.010
camera type eye developmentGO:00430102220.010
negative regulation of ras protein signal transductionGO:004658010.010
sleepGO:003043110.010
lipid homeostasisGO:005508830.010
viral processGO:001603210.010
rna 3 end processingGO:003112320.010
negative regulation of multi organism processGO:004390130.010
sequestering of calcium ionGO:005120830.010
axon developmentGO:00615641660.010
carbohydrate biosynthetic processGO:001605110.010
protein targeting to membraneGO:000661210.010
determination of left right symmetryGO:00073681790.010
negative regulation of macromolecule metabolic processGO:0010605760.010
protein homooligomerizationGO:005126030.010
negative regulation of epithelial cell proliferationGO:005068010.010
mitochondrial atp synthesis coupled electron transportGO:004277510.010
intracellular mrna localizationGO:000829810.010
neuromuscular synaptic transmissionGO:000727420.010
response to organic substanceGO:00100331530.010
nucleobase containing compound transportGO:001593120.010
positive regulation of dna templated transcription elongationGO:003278610.010
phosphate containing compound metabolic processGO:00067961080.010
negative regulation of map kinase activityGO:004340720.010

tbck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.024
disease of cellular proliferationDOID:1456600.016
musculoskeletal system diseaseDOID:1700.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
sensory system diseaseDOID:005015500.014
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
disease of metabolismDOID:001466700.012
muscular diseaseDOID:008000000.010
myopathyDOID:42300.010
muscle tissue diseaseDOID:6600.010
cardiovascular system diseaseDOID:128700.010