Danio rerio

42 known processes

hspg2

heparan sulfate proteoglycan 2

hspg2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal muscle organ developmentGO:0060538780.949
cell projection organizationGO:00300302840.746
vasculature developmentGO:00019442780.732
cellular component morphogenesisGO:00329893360.690
heart developmentGO:00075073130.484
cellular component assemblyGO:00226071700.448
cell substrate adhesionGO:003158940.433
striated muscle tissue developmentGO:00147061100.411
organelle assemblyGO:00709251100.401
myofibril assemblyGO:0030239480.374
blood vessel morphogenesisGO:00485142160.368
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.350
skeletal muscle tissue developmentGO:0007519670.331
cell migrationGO:00164772370.316
lymph vessel developmentGO:0001945270.312
embryonic organ morphogenesisGO:00485622740.309
regulation of synapse assemblyGO:005196330.309
cellular component biogenesisGO:00440851780.306
muscle structure developmentGO:00610611960.305
sensory organ developmentGO:00074233930.295
actomyosin structure organizationGO:0031032530.280
cell morphogenesisGO:00009022890.275
lymphangiogenesisGO:0001946250.268
blood circulationGO:0008015870.266
cell matrix adhesionGO:000716040.253
heart loopingGO:0001947940.247
glial cell migrationGO:000834730.234
circulatory system processGO:0003013870.230
cell projection morphogenesisGO:00488582440.229
organelle organizationGO:00069962270.225
sarcomere organizationGO:0045214260.213
axonogenesisGO:00074091520.210
single organism organelle organizationGO:19025891990.208
lymph vessel morphogenesisGO:0036303250.206
cytoskeleton organizationGO:0007010960.203
regulation of cellular component organizationGO:0051128860.202
cell morphogenesis involved in differentiationGO:00009041950.197
embryonic heart tube morphogenesisGO:00031431080.197
tube morphogenesisGO:00352393490.193
cell motilityGO:00488702440.193
localization of cellGO:00516742440.190
regulation of synapse organizationGO:005080730.178
nitrogen compound metabolic processGO:00068073190.164
striated muscle cell developmentGO:00550021080.162
actin filament based processGO:0030029640.158
regulation of biological qualityGO:00650082630.158
larval developmentGO:000216420.157
embryonic organ developmentGO:00485683810.155
cell adhesionGO:0007155400.154
regulation of synaptic growth at neuromuscular junctionGO:000858210.147
taxisGO:00423301090.147
adult behaviorGO:003053420.145
embryonic skeletal system developmentGO:0048706970.142
muscle cell differentiationGO:00426921390.142
heart processGO:0003015710.141
muscle tissue developmentGO:00605371100.138
heart contractionGO:0060047710.137
synaptic growth at neuromuscular junctionGO:005112420.136
negative regulation of sequestering of calcium ionGO:005128340.136
embryo development ending in birth or egg hatchingGO:00097922710.136
morphogenesis of an epitheliumGO:00020093330.135
actin cytoskeleton organizationGO:0030036630.133
calcium ion transmembrane transportGO:0070588130.133
neuron differentiationGO:00301823530.131
axon developmentGO:00615641660.130
muscle organ developmentGO:00075171010.129
macromolecular complex subunit organizationGO:0043933740.124
protein metabolic processGO:00195381830.124
eye developmentGO:00016542770.122
cellular component movementGO:00069283350.118
brain developmentGO:00074202930.116
regulation of protein catabolic processGO:004217610.112
cell part morphogenesisGO:00329902460.108
blood vessel developmentGO:00015682460.106
digestive system developmentGO:00551232890.104
regulation of cell matrix adhesionGO:000195210.101
regulation of developmental processGO:00507932470.096
ameboidal type cell migrationGO:00016671430.095
regulation of macromolecule metabolic processGO:00602553170.095
epithelial tube morphogenesisGO:00605621480.094
regulation of cell shapeGO:000836010.091
neuron developmentGO:00486662620.091
regulation of cellular metabolic processGO:00313233200.090
cell morphogenesis involved in neuron differentiationGO:00486671630.086
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.086
stem cell proliferationGO:007208940.086
behaviorGO:0007610740.086
chordate embryonic developmentGO:00430092710.085
central nervous system developmentGO:00074173870.085
cellular aromatic compound metabolic processGO:00067252950.083
system processGO:00030081850.081
generation of neuronsGO:00486993850.081
nuclear divisionGO:0000280230.081
specification of symmetryGO:00097992040.079
nucleoside monophosphate catabolic processGO:000912540.078
macrophage chemotaxisGO:004824630.078
mitotic cell cycleGO:0000278640.077
peptidyl serine phosphorylationGO:001810510.077
cellular component assembly involved in morphogenesisGO:00109271070.076
regulation of system processGO:0044057400.076
regulation of mrna splicing via spliceosomeGO:004802430.075
cytosolic calcium ion transportGO:006040130.074
neuron projection morphogenesisGO:00488121610.074
nucleoside phosphate metabolic processGO:0006753280.074
positive regulation of cellular component biogenesisGO:004408930.074
determination of heart left right asymmetryGO:00613711170.073
establishment of localizationGO:00512342440.072
neurological system processGO:0050877620.071
response to chemicalGO:00422213200.070
signal transductionGO:00071654550.069
regulation of nucleotide catabolic processGO:003081120.069
phosphorus metabolic processGO:00067931090.068
cell projection assemblyGO:0030031640.067
positive regulation of lymphangiogenesisGO:190149230.066
positive regulation of endothelial cell proliferationGO:000193810.066
regulation of dendrite developmentGO:005077330.064
cellular macromolecule metabolic processGO:00442603910.062
cell fate commitmentGO:0045165990.061
digestive tract morphogenesisGO:00485462310.061
regulation of dendrite morphogenesisGO:004881430.061
guanosine containing compound metabolic processGO:190106840.060
regulation of rna metabolic processGO:00512522240.059
heterocycle metabolic processGO:00464832900.059
regulation of metabolic processGO:00192223590.059
biological adhesionGO:0022610400.059
rna biosynthetic processGO:00327741810.059
heart morphogenesisGO:00030071560.058
regulation of cell substrate adhesionGO:001081010.058
guanosine containing compound catabolic processGO:190106920.057
gland developmentGO:00487321430.057
actin filament organizationGO:0007015150.056
positive regulation of biological processGO:00485182530.056
meiotic nuclear divisionGO:000712640.056
positive regulation of multicellular organismal processGO:0051240520.055
cell cycle processGO:0022402530.054
spermatid differentiationGO:004851520.054
modification dependent macromolecule catabolic processGO:004363230.053
modification dependent protein catabolic processGO:001994130.053
carboxylic acid metabolic processGO:0019752220.052
cognitionGO:005089010.052
mitotic cell cycle processGO:1903047480.052
neuroblast proliferationGO:000740520.051
regulation of actin cytoskeleton organizationGO:003295680.051
positive regulation of transportGO:005105020.050
embryonic heart tube developmentGO:00350501330.050
organic acid metabolic processGO:0006082310.049
positive regulation of cellular processGO:00485222010.049
negative regulation of biological processGO:00485193040.048
positive regulation of cytosolic calcium ion concentrationGO:000720440.048
regulation of cell communicationGO:00106462320.048
regulation of signal transductionGO:00099662250.048
regulation of organelle organizationGO:0033043290.047
regulation of tube sizeGO:003515020.047
cellular biosynthetic processGO:00442492860.046
neuron projection developmentGO:00311751800.046
chemotaxisGO:00069351040.046
programmed cell deathGO:00125011190.045
cell substrate junction assemblyGO:000704420.045
gastrulationGO:00073692080.045
cellular protein metabolic processGO:00442671290.045
response to topologically incorrect proteinGO:003596620.044
purine ribonucleoside monophosphate catabolic processGO:000916940.044
regulation of primary metabolic processGO:00800903110.044
ubiquitin dependent protein catabolic processGO:000651130.044
digestive tract developmentGO:00485652650.044
gene expressionGO:00104672520.043
nucleobase containing compound metabolic processGO:00061392740.043
locomotory behaviorGO:0007626340.043
mesodermal cell migrationGO:0008078120.042
locomotionGO:00400113130.041
striated muscle cell differentiationGO:00511461290.041
atp catabolic processGO:000620040.040
regulation of synaptic plasticityGO:004816710.040
regulation of anatomical structure morphogenesisGO:00226031300.040
positive regulation of epithelial cell migrationGO:001063420.040
single organism metabolic processGO:00447102170.039
organic cyclic compound metabolic processGO:19013603010.039
action potentialGO:0001508190.039
g2 m transition of mitotic cell cycleGO:000008640.039
small molecule metabolic processGO:0044281770.039
cellular amine metabolic processGO:004410620.039
regulation of gene expressionGO:00104682650.039
cell surface receptor signaling pathwayGO:00071663250.038
sprouting angiogenesisGO:0002040530.038
cytokinesisGO:000091030.038
protein homooligomerizationGO:005126030.038
multi organism processGO:00517041340.038
regulation of neurological system processGO:003164420.038
proteasomal protein catabolic processGO:001049820.037
regulation of blood circulationGO:1903522320.037
negative regulation of synapse assemblyGO:005196420.037
calcium ion transport into cytosolGO:006040230.037
positive regulation of leukocyte chemotaxisGO:000269010.037
collagen metabolic processGO:003296320.037
regulation of cell migrationGO:0030334400.036
positive regulation of cellular catabolic processGO:003133130.036
g2 dna damage checkpointGO:003157230.036
release of sequestered calcium ion into cytosolGO:005120930.036
regulation of macromolecule biosynthetic processGO:00105562250.035
neuron projection guidanceGO:0097485860.035
anterior posterior pattern specificationGO:00099521520.035
phosphate containing compound metabolic processGO:00067961080.035
rna metabolic processGO:00160702190.035
regulation of rna biosynthetic processGO:20011412130.034
biosynthetic processGO:00090582940.034
multicellular organism growthGO:003526440.034
mesenchyme developmentGO:00604851270.034
ribonucleoside monophosphate catabolic processGO:000915840.033
protein localization to plasma membraneGO:007265910.033
locomotor rhythmGO:004547530.033
cellular process involved in reproduction in multicellular organismGO:0022412280.032
meiotic cell cycle processGO:190304630.031
cellular protein modification processGO:00064641000.031
smooth muscle contractionGO:000693920.031
vascular endothelial growth factor signaling pathwayGO:003808430.031
positive regulation of endothelial cell migrationGO:001059520.031
long chain fatty acid metabolic processGO:000167610.031
glycosaminoglycan metabolic processGO:003020390.031
regulation of multicellular organismal processGO:00512392770.031
aminoglycan metabolic processGO:000602290.031
multicellular organismal signalingGO:0035637220.031
g protein coupled receptor signaling pathwayGO:0007186740.030
determination of left right symmetryGO:00073681790.030
maintenance of locationGO:005123540.030
positive regulation of leukocyte migrationGO:000268720.030
cellular nitrogen compound metabolic processGO:00346412900.030
neuromuscular synaptic transmissionGO:000727420.030
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.030
regulation of response to stimulusGO:00485832690.029
oxoacid metabolic processGO:0043436310.029
cellular protein catabolic processGO:004425740.029
organonitrogen compound metabolic processGO:1901564740.029
stem cell differentiationGO:00488631170.029
regulation of alternative mrna splicing via spliceosomeGO:000038110.028
regulation of cellular amino acid metabolic processGO:000652100.028
mitotic dna integrity checkpointGO:004477440.028
developmental programmed cell deathGO:001062340.028
amine metabolic processGO:000930820.028
regulation of endothelial cell proliferationGO:000193610.028
macromolecule modificationGO:00434121110.028
cell junction organizationGO:0034330110.028
cell cycle g2 m phase transitionGO:004483940.028
adherens junction organizationGO:003433240.028
muscle contractionGO:0006936180.028
cell migration involved in gastrulationGO:0042074790.027
cell fate specificationGO:0001708680.027
body morphogenesisGO:0010171160.026
regulation of cytoskeleton organizationGO:0051493110.026
negative regulation of cellular processGO:00485232830.026
myotube differentiationGO:0014902450.026
sensory organ morphogenesisGO:00905962000.026
transportGO:00068102200.025
regulation of heart contractionGO:0008016320.025
response to stressGO:00069502630.025
ras protein signal transductionGO:000726570.024
convergent extension involved in gastrulationGO:0060027710.024
membrane fusionGO:006102520.024
regulation of nitrogen compound metabolic processGO:00511712510.024
determination of bilateral symmetryGO:00098552040.024
single organismal cell cell adhesionGO:0016337290.024
axon guidanceGO:0007411860.024
purine nucleoside monophosphate catabolic processGO:000912840.024
agingGO:000756820.024
appendage developmentGO:0048736800.024
lipid homeostasisGO:005508830.024
positive regulation of map kinase activityGO:004340630.023
epidermal cell fate specificationGO:000995740.023
catabolic processGO:0009056320.023
embryonic skeletal system morphogenesisGO:0048704930.023
regulation of multicellular organism growthGO:004001440.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of purine nucleotide catabolic processGO:003312120.023
neuronal action potentialGO:0019228180.023
head developmentGO:00603223030.023
regulation of rho protein signal transductionGO:003502320.023
response to external stimulusGO:00096052640.023
positive regulation of locomotionGO:0040017140.023
gtp catabolic processGO:000618420.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.023
multicellular organism reproductionGO:0032504350.022
muscle cell developmentGO:00550011150.022
protein complex assemblyGO:0006461300.022
multi organism reproductive processGO:0044703360.022
outflow tract morphogenesisGO:000315110.022
sensory perception of chemical stimulusGO:000760630.022
positive regulation of phospholipase c activityGO:001086310.022
organelle localizationGO:0051640490.022
establishment of protein localization to organelleGO:007259440.021
tor signalingGO:003192970.021
muscle attachmentGO:001620390.021
regulation of neuron differentiationGO:0045664560.021
sequestering of calcium ionGO:005120830.021
embryonic cranial skeleton morphogenesisGO:0048701900.021
single organism membrane fusionGO:004480120.021
mononuclear cell migrationGO:007167410.021
positive regulation of stem cell proliferationGO:200064810.021
regulation of mrna processingGO:005068430.021
tissue homeostasisGO:0001894250.020
skeletal system developmentGO:00015011810.020
sequestering of metal ionGO:005123830.020
forebrain developmentGO:0030900960.020
protein complex subunit organizationGO:0071822460.020
alternative mrna splicing via spliceosomeGO:000038010.020
cellular macromolecule biosynthetic processGO:00346452240.020
axon ensheathmentGO:0008366180.020
regulation of membrane potentialGO:0042391230.020
skeletal muscle thin filament assemblyGO:003024040.019
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.019
positive regulation of catabolic processGO:000989640.019
regulation of endocrine processGO:004406020.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
hormone secretionGO:004687920.019
ribose phosphate metabolic processGO:0019693270.019
macromolecular complex disassemblyGO:003298410.019
developmental process involved in reproductionGO:0003006270.019
regulation of transcription dna templatedGO:00063552130.018
wound healingGO:0042060900.018
regulation of sequestering of calcium ionGO:005128240.018
spermatid developmentGO:000728620.018
positive regulation of cellular amine metabolic processGO:003324000.018
embryonic limb morphogenesisGO:003032620.018
regulation of blood vessel sizeGO:005088020.018
single organism cell adhesionGO:0098602290.018
multicellular organismal metabolic processGO:004423620.018
microtubule organizing center organizationGO:003102310.018
positive regulation of macrophage chemotaxisGO:001075910.018
endosomal transportGO:001619720.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
regulation of stem cell proliferationGO:007209120.017
notch signaling pathwayGO:0007219350.017
odontogenesis of dentin containing toothGO:004247510.017
actin mediated cell contractionGO:007025210.017
nuclear importGO:005117030.017
organic substance biosynthetic processGO:19015762890.017
fatty acid biosynthetic processGO:000663340.017
small gtpase mediated signal transductionGO:000726480.017
histone modificationGO:0016570200.017
regulation of locomotionGO:0040012550.017
cell proliferationGO:0008283800.017
intracellular signal transductionGO:0035556850.017
multicellular organismal reproductive processGO:0048609350.016
divalent inorganic cation homeostasisGO:0072507220.016
oocyte developmentGO:0048599140.016
microtubule cytoskeleton organization involved in mitosisGO:190285010.016
regulation of leukocyte migrationGO:000268580.016
actin polymerization or depolymerizationGO:000815420.016
organelle fissionGO:0048285230.016
nuclear migrationGO:000709730.016
positive regulation of epithelial cell proliferationGO:005067910.016
camera type eye developmentGO:00430102220.016
sexual reproductionGO:0019953360.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of circadian rhythmGO:004275240.016
cytoskeleton dependent cytokinesisGO:006164030.016
regulation of cell motilityGO:2000145460.016
regulation of apoptotic processGO:0042981980.016
cell deathGO:00082191210.016
gtp metabolic processGO:004603940.016
regulation of nucleoside metabolic processGO:000911820.016
single organism membrane organizationGO:0044802200.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
growthGO:00400071740.015
peptidyl serine modificationGO:001820920.015
regulation of organelle assemblyGO:190211540.015
negative regulation of protein kinase activityGO:000646940.015
establishment of localization in cellGO:0051649770.015
regulation of behaviorGO:0050795240.014
microtubule cytoskeleton organizationGO:0000226330.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
neural retina developmentGO:0003407490.014
heterocycle catabolic processGO:0046700150.014
cytokinetic processGO:003250620.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
regulation of synapse structure and activityGO:005080350.014
notochord developmentGO:0030903540.014
protein phosphorylationGO:0006468470.014
water homeostasisGO:003010440.014
immune system developmentGO:00025201910.014
homeostatic processGO:00425921420.014
heterocycle biosynthetic processGO:00181302150.014
positive regulation of gtp catabolic processGO:003312610.013
cell substrate adherens junction assemblyGO:000704510.013
nucleotide metabolic processGO:0009117280.013
regulation of signalingGO:00230512350.013
protein dephosphorylationGO:000647030.013
regulation of skeletal muscle tissue developmentGO:004864140.013
positive regulation of developmental processGO:0051094500.013
skeletal system morphogenesisGO:00487051020.013
chromosome organizationGO:0051276310.013
cellular localizationGO:0051641970.013
negative regulation of calcium dependent cell cell adhesionGO:004658810.013
pathway restricted smad protein phosphorylationGO:006038910.013
lipid metabolic processGO:0006629520.013
anatomical structure homeostasisGO:0060249360.013
single organism reproductive processGO:0044702400.013
negative regulation of kinase activityGO:003367340.013
basement membrane assemblyGO:007083130.013
hepaticobiliary system developmentGO:0061008980.013
venous blood vessel developmentGO:006084190.013
cell chemotaxisGO:0060326170.013
mrna processingGO:0006397140.013
single organism transportGO:00447652060.013
vasculogenesisGO:0001570410.013
myeloid leukocyte migrationGO:0097529120.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
adherens junction assemblyGO:003433310.012
cellular component disassemblyGO:002241110.012
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.012
regulation of vasculature developmentGO:1901342330.012
response to oxygen containing compoundGO:1901700550.012
internal protein amino acid acetylationGO:000647520.012
deathGO:00162651210.012
multicellular organismal macromolecule metabolic processGO:004425920.012
somite developmentGO:0061053960.012
artery developmentGO:0060840220.012
granulocyte chemotaxisGO:0071621110.012
regulation of protein metabolic processGO:0051246560.012
oocyte differentiationGO:0009994140.012
cell cell signalingGO:0007267520.012
cellular response to external stimulusGO:007149620.012
reproductive processGO:0022414400.012
regulation of actin filament based processGO:003297090.012
inorganic cation transmembrane transportGO:0098662500.012
regulation of cellular protein catabolic processGO:190336210.012
macromolecular complex assemblyGO:0065003350.012
inner ear developmentGO:00488391260.012
nucleic acid templated transcriptionGO:00976591810.012
tissue remodelingGO:004877140.012
purine ribonucleoside triphosphate metabolic processGO:000920590.012
myelinationGO:0042552180.012
oogenesisGO:0048477140.012
positive regulation of synapse assemblyGO:005196510.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
non canonical wnt signaling pathwayGO:0035567130.012
negative regulation of protein phosphorylationGO:000193340.012
regulation of gtp catabolic processGO:003312420.011
apoptotic process involved in developmentGO:190274220.011
endocrine processGO:005088620.011
protein localization to membraneGO:007265790.011
stem cell divisionGO:001714510.011
gamete generationGO:0007276330.011
xanthophore differentiationGO:005093630.011
cellular calcium ion homeostasisGO:0006874130.011
regulation of lymphangiogenesisGO:190149040.011
regulation of syncytium formation by plasma membrane fusionGO:006014220.011
aromatic compound biosynthetic processGO:00194382170.011
central nervous system formationGO:002155610.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
cellular metal ion homeostasisGO:0006875160.011
axonal defasciculationGO:000741420.011
regenerationGO:0031099910.011
cell fate determinationGO:000170970.011
cellular response to starvationGO:000926710.011
osteoclast developmentGO:003603510.011
protein modification processGO:00362111000.011
macromolecule biosynthetic processGO:00090592270.011
larval behaviorGO:003053750.011
eye morphogenesisGO:00485921440.011
vesicle mediated transportGO:0016192220.011
cellular protein complex assemblyGO:0043623190.010
er nucleus signaling pathwayGO:000698420.010
regulation of phosphorus metabolic processGO:0051174430.010
synapse organizationGO:0050808210.010
protein acetylationGO:000647320.010
cell death in response to oxidative stressGO:003647320.010
fin developmentGO:0033333770.010
regulation of chronic inflammatory responseGO:000267610.010
periodic partitioningGO:000736510.010
centrosome organizationGO:005129710.010
mitotic g2 dna damage checkpointGO:000709530.010
autophagyGO:000691440.010

hspg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.127
muscular diseaseDOID:008000000.056
muscle tissue diseaseDOID:6600.056
musculoskeletal system diseaseDOID:1700.056
nervous system diseaseDOID:86300.031
cardiovascular system diseaseDOID:128700.027
heart diseaseDOID:11400.017
myopathyDOID:42300.017
intrinsic cardiomyopathyDOID:006003600.017
cardiomyopathyDOID:005070000.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
cancerDOID:16200.017