Danio rerio

14 known processes

p2rx1

purinergic receptor P2X, ligand-gated ion channel, 1

(Aliases: p2xr1)

p2rx1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.065
positive regulation of cellular component biogenesisGO:004408930.054
stem cell maintenanceGO:001982740.038
agingGO:000756820.038
cellular component movementGO:00069283350.034
signal transductionGO:00071654550.034
Human
regulation of synapse assemblyGO:005196330.033
maintenance of locationGO:005123540.033
positive regulation of cellular catabolic processGO:003133130.032
positive regulation of transportGO:005105020.031
stem cell proliferationGO:007208940.031
regulation of protein complex assemblyGO:004325430.031
regulation of biological qualityGO:00650082630.030
Rat
nucleocytoplasmic transportGO:000691340.029
positive regulation of catabolic processGO:000989640.029
regulation of mrna processingGO:005068430.028
phagocytosisGO:000690930.027
nuclear transportGO:005116940.027
guanosine containing compound metabolic processGO:190106840.026
synaptic growth at neuromuscular junctionGO:005112420.026
regulation of multicellular organism growthGO:004001440.026
cognitionGO:005089010.025
regulation of cytokine productionGO:000181730.025
regulation of cell activationGO:005086510.025
central nervous system developmentGO:00074173870.025
b cell activationGO:004211320.024
actin polymerization or depolymerizationGO:000815420.024
amine metabolic processGO:000930820.024
cellular component biogenesisGO:00440851780.024
Rat
cell surface receptor signaling pathwayGO:00071663250.024
Human
leukocyte proliferationGO:007066110.024
cellular component morphogenesisGO:00329893360.024
cell projection organizationGO:00300302840.023
cell matrix adhesionGO:000716040.023
protein polymerizationGO:005125840.023
response to chemicalGO:00422213200.023
cell morphogenesisGO:00009022890.023
gtp metabolic processGO:004603940.023
regulation of synapse organizationGO:005080730.023
phagocytosis engulfmentGO:000691110.023
response to drugGO:004249330.023
regulation of protein catabolic processGO:004217610.023
gtp catabolic processGO:000618420.022
lipid storageGO:001991510.022
cell projection morphogenesisGO:00488582440.022
multicellular organism growthGO:003526440.022
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
morphogenesis of an epitheliumGO:00020093330.022
positive regulation of cell cycleGO:004578730.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.022
regulation of blood pressureGO:000821710.022
Rat
establishment of localizationGO:00512342440.022
mononuclear cell proliferationGO:003294310.022
cell part morphogenesisGO:00329902460.021
internal protein amino acid acetylationGO:000647520.021
regulation of cellular amino acid metabolic processGO:000652100.021
regulation of multicellular organismal processGO:00512392770.021
regulation of establishment of protein localizationGO:007020140.021
autophagyGO:000691440.021
single organism organelle organizationGO:19025891990.021
regulation of protein localization to nucleusGO:190018020.021
regulation of cellular amine metabolic processGO:003323800.021
peptidyl lysine acetylationGO:001839420.021
positive regulation of gtp catabolic processGO:003312610.021
positive regulation of immune effector processGO:000269930.021
organic cyclic compound metabolic processGO:19013603010.021
female sex differentiationGO:004666040.021
localization of cellGO:00516742440.021
protein import into nucleusGO:000660630.021
adult behaviorGO:003053420.021
generation of neuronsGO:00486993850.021
multi organism cellular processGO:004476420.020
cell substrate adhesionGO:003158940.020
response to external stimulusGO:00096052640.020
regulation of cytoplasmic transportGO:190364940.020
blood vessel developmentGO:00015682460.020
internal peptidyl lysine acetylationGO:001839320.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of nucleocytoplasmic transportGO:004682220.020
establishment of protein localization to organelleGO:007259440.020
nitrogen compound metabolic processGO:00068073190.020
carboxylic acid metabolic processGO:0019752220.020
positive regulation of cytokine productionGO:000181920.020
cellular ketone metabolic processGO:0042180110.019
cellular response to extracellular stimulusGO:003166820.019
positive regulation of cytoskeleton organizationGO:005149530.019
cell migrationGO:00164772370.019
single organism metabolic processGO:00447102170.019
regulation of cell shapeGO:000836010.019
locomotionGO:00400113130.019
meiotic cell cycle processGO:190304630.019
neuron differentiationGO:00301823530.019
protein acetylationGO:000647320.019
cellular response to starvationGO:000926710.019
digestive system developmentGO:00551232890.019
protein acylationGO:004354330.019
guanosine containing compound catabolic processGO:190106920.019
immune system processGO:00023762410.019
protein importGO:001703830.019
cellular macromolecule metabolic processGO:00442603910.019
female gonad developmentGO:000858540.019
regulation of stem cell differentiationGO:200073640.019
cellular component disassemblyGO:002241110.019
positive regulation of protein complex assemblyGO:003133420.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of multicellular organismal developmentGO:20000262230.018
lymphocyte proliferationGO:004665110.018
regulation of protein targetingGO:190353320.018
regulation of intracellular protein transportGO:003315730.018
cell motilityGO:00488702440.018
lipid catabolic processGO:001604240.018
regulation of protein import into nucleusGO:004230620.018
mitochondrion organizationGO:000700540.018
membrane invaginationGO:001032410.018
adherens junction organizationGO:003433240.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
system processGO:00030081850.018
Rat
protein targeting to nucleusGO:004474430.018
vasculature developmentGO:00019442780.018
cellular response to nutrient levelsGO:003166920.018
small molecule metabolic processGO:0044281770.018
organelle organizationGO:00069962270.018
transportGO:00068102200.018
positive regulation of biological processGO:00485182530.018
nucleobase containing compound metabolic processGO:00061392740.018
ubiquitin dependent protein catabolic processGO:000651130.018
regulation of protein transportGO:005122330.018
secondary metabolic processGO:001974830.017
post embryonic organ developmentGO:004856940.017
regulation of dna templated transcription elongationGO:003278430.017
i kappab kinase nf kappab signalingGO:000724940.017
meiotic nuclear divisionGO:000712640.017
regulation of bindingGO:005109830.017
organonitrogen compound metabolic processGO:1901564740.017
cellular amine metabolic processGO:004410620.017
tissue remodelingGO:004877140.017
membrane fusionGO:006102520.017
eye developmentGO:00016542770.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
negative regulation of protein phosphorylationGO:000193340.017
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.017
regulation of metal ion transportGO:001095940.017
positive regulation of protein polymerizationGO:003227320.017
regulation of purine nucleotide catabolic processGO:003312120.017
gene expressionGO:00104672520.017
development of primary female sexual characteristicsGO:004654540.017
regulation of production of molecular mediator of immune responseGO:000270010.017
developmental growthGO:00485891660.017
organic acid metabolic processGO:0006082310.017
negative regulation of catabolic processGO:000989530.017
blood vessel morphogenesisGO:00485142160.017
protein localization to nucleusGO:003450430.017
tube morphogenesisGO:00352393490.017
regulation of cellular ketone metabolic processGO:001056570.017
proteasomal protein catabolic processGO:001049820.017
single organism nuclear importGO:190259330.017
regulation of gtp catabolic processGO:003312420.016
inositol lipid mediated signalingGO:004801720.016
regulation of reproductive processGO:200024140.016
rna localizationGO:000640340.016
nucleoside monophosphate catabolic processGO:000912540.016
nuclear importGO:005117030.016
immune system developmentGO:00025201910.016
proteolysis involved in cellular protein catabolic processGO:005160330.016
growthGO:00400071740.016
response to carbohydrateGO:000974330.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
cellular nitrogen compound metabolic processGO:00346412900.016
modification dependent macromolecule catabolic processGO:004363230.016
protein secretionGO:000930610.016
regulation of neural precursor cell proliferationGO:200017730.016
positive regulation of nucleoside metabolic processGO:004597910.016
cytokinesisGO:000091030.016
regulation of signal transductionGO:00099662250.016
regulation of sodium ion transportGO:000202820.016
histone h3 k4 methylationGO:005156820.016
head developmentGO:00603223030.016
embryonic organ developmentGO:00485683810.016
cellular amino acid metabolic processGO:000652070.016
regulation of signalingGO:00230512350.016
regulation of protein polymerizationGO:003227120.016
interspecies interaction between organismsGO:004441940.016
regulation of gtpase activityGO:004308720.016
protein dephosphorylationGO:000647030.016
immunoglobulin mediated immune responseGO:001606430.015
positive regulation of cell adhesionGO:004578510.015
compound eye developmentGO:004874920.015
meiotic chromosome segregationGO:004513230.015
modification dependent protein catabolic processGO:001994130.015
somatic stem cell maintenanceGO:003501910.015
actin filament polymerizationGO:003004120.015
protein complex disassemblyGO:004324110.015
cellular amide metabolic processGO:004360340.015
angiogenesisGO:00015251580.015
regulation of cell projection assemblyGO:006049140.015
cellular protein catabolic processGO:004425740.015
chemosensory behaviorGO:000763510.015
regulation of response to stimulusGO:00485832690.015
positive regulation of cellular amine metabolic processGO:003324000.015
negative regulation of biological processGO:00485193040.015
response to uvGO:000941130.015
regulation of filopodium assemblyGO:005148920.015
cellular response to oxygen levelsGO:007145310.015
cell morphogenesis involved in differentiationGO:00009041950.015
viral processGO:001603210.015
regulation of reactive oxygen species metabolic processGO:200037720.015
regulation of cell substrate adhesionGO:001081010.015
gland developmentGO:00487321430.015
embryo development ending in birth or egg hatchingGO:00097922710.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
production of molecular mediator of immune responseGO:000244020.015
oxoacid metabolic processGO:0043436310.015
peptide transportGO:001583310.015
heterocycle metabolic processGO:00464832900.015
regulation of developmental processGO:00507932470.014
b cell mediated immunityGO:001972430.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
protein metabolic processGO:00195381830.014
neuron developmentGO:00486662620.014
biosynthetic processGO:00090582940.014
axonogenesisGO:00074091520.014
positive regulation of map kinase activityGO:004340630.014
regulation of cell matrix adhesionGO:000195210.014
atp catabolic processGO:000620040.014
cellular response to external stimulusGO:007149620.014
cellular aromatic compound metabolic processGO:00067252950.014
protein localization to plasma membraneGO:007265910.014
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of transporter activityGO:003240920.014
response to monosaccharideGO:003428430.014
positive regulation of cell activationGO:005086710.014
sleepGO:003043110.014
glial cell migrationGO:000834730.014
sensory organ developmentGO:00074233930.014
regulation of inflammatory responseGO:005072720.014
hemopoiesisGO:00300971830.014
regulation of stem cell proliferationGO:007209120.014
extrinsic apoptotic signaling pathwayGO:009719130.014
somatic muscle developmentGO:000752540.014
regulation of transmembrane transporter activityGO:002289820.014
dna templated transcription elongationGO:000635430.014
germ line stem cell maintenanceGO:003071820.014
cellular component assemblyGO:00226071700.014
Rat
protein heterooligomerizationGO:005129110.014
Rat
embryonic organ morphogenesisGO:00485622740.014
macromolecular complex disassemblyGO:003298410.014
negative regulation of mapk cascadeGO:004340940.014
determination of left right symmetryGO:00073681790.014
smooth muscle contractionGO:000693920.014
regulation of organ growthGO:004662030.014
lateral inhibitionGO:004633110.014
brain developmentGO:00074202930.014
response to hexoseGO:000974630.014
negative regulation of cellular catabolic processGO:003133030.014
rna metabolic processGO:00160702190.014
regulation of meiotic cell cycleGO:005144510.014
ribonucleoside monophosphate catabolic processGO:000915840.013
ventricular cardiac muscle tissue developmentGO:000322930.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
regulation of metabolic processGO:00192223590.013
regulation of erk1 and erk2 cascadeGO:007037240.013
positive regulation of translationGO:004572710.013
regulation of carbohydrate metabolic processGO:000610940.013
cellular biosynthetic processGO:00442492860.013
regulation of wound healingGO:006104120.013
positive regulation of dna templated transcription elongationGO:003278610.013
organelle assemblyGO:00709251100.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
negative regulation of cytokine productionGO:000181810.013
positive regulation of gtpase activityGO:004354710.013
digestive tract developmentGO:00485652650.013
nuclear exportGO:005116810.013
positive regulation of secretionGO:005104710.013
zymogen activationGO:003163830.013
neuroblast proliferationGO:000740520.013
negative regulation of map kinase activityGO:004340720.013
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.013
intracellular mrna localizationGO:000829810.013
negative regulation of synapse assemblyGO:005196420.013
rna 3 end processingGO:003112320.013
lamellipodium organizationGO:009758110.013
positive regulation of dna metabolic processGO:005105410.013
stem cell divisionGO:001714510.013
negative regulation of kinase activityGO:003367340.013
regulation of autophagyGO:001050630.013
neuron projection morphogenesisGO:00488121610.013
locomotor rhythmGO:004547530.013
negative regulation of protein kinase activityGO:000646940.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
small molecule catabolic processGO:004428230.013
regulation of blood vessel sizeGO:005088020.013
Rat
determination of bilateral symmetryGO:00098552040.013
single organism transportGO:00447652060.013
digestive tract morphogenesisGO:00485462310.013
negative regulation of protein transportGO:005122430.013
hormone secretionGO:004687920.013
regulation of nervous system developmentGO:0051960900.013
regulation of endocrine processGO:004406020.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
regulation of nitrogen compound metabolic processGO:00511712510.012
regulation of response to biotic stimulusGO:000283120.012
sensory perception of chemical stimulusGO:000760630.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
positive regulation of striated muscle cell differentiationGO:005115510.012
multicellular organismal metabolic processGO:004423620.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
cellular response to hypoxiaGO:007145610.012
regulation of tube sizeGO:003515020.012
Rat
cellular response to chemical stimulusGO:00708871570.012
regulation of dna recombinationGO:000001820.012
regulation of muscle contractionGO:000693730.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
single organism membrane fusionGO:004480120.012
establishment of protein localization to plasma membraneGO:009000210.012
regulation of cellular metabolic processGO:00313233200.012
cell cycle g1 s phase transitionGO:004484310.012
catechol containing compound metabolic processGO:000971220.012
regulation of dna replicationGO:000627530.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
amino acid transportGO:000686520.012
neuron projection developmentGO:00311751800.012
sprouting angiogenesisGO:0002040530.012
nucleic acid metabolic processGO:00903042440.012
developmental programmed cell deathGO:001062340.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
regulation of rho protein signal transductionGO:003502320.012
heart developmentGO:00075073130.012
cellular response to molecule of bacterial originGO:007121930.012
action potentialGO:0001508190.012
Rat
camera type eye developmentGO:00430102220.012
erk1 and erk2 cascadeGO:007037140.012
muscle cell developmentGO:00550011150.012
specification of symmetryGO:00097992040.012
cellular response to radiationGO:007147840.012
regulation of gene expressionGO:00104682650.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of photoreceptor cell differentiationGO:004653220.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
exocytosisGO:000688710.012
regulation of macromolecule metabolic processGO:00602553170.012
cell cell recognitionGO:000998810.012
axon developmentGO:00615641660.012
spermatid developmentGO:000728620.012
organic substance biosynthetic processGO:19015762890.012
aromatic compound biosynthetic processGO:00194382170.012
regionalizationGO:00030022740.012
positive regulation of secretion by cellGO:190353210.012
regulation of circadian rhythmGO:004275240.011
regulation of cell differentiationGO:00455951420.011
epidermal cell fate specificationGO:000995740.011
rna transportGO:005065820.011
cell deathGO:00082191210.011
multi organism processGO:00517041340.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
purine nucleoside monophosphate catabolic processGO:000912840.011
positive regulation of striated muscle tissue developmentGO:004584410.011
antimicrobial humoral responseGO:001973020.011
hormone transportGO:000991420.011
cellular protein metabolic processGO:00442671290.011
response to corticosteroidGO:003196010.011
positive regulation of epithelial cell migrationGO:001063420.011
regulation of synaptic plasticityGO:004816710.011
positive regulation of chromatin modificationGO:190331010.011
carbohydrate homeostasisGO:003350010.011
fertilizationGO:000956630.011
phosphatidylinositol mediated signalingGO:004801520.011
organic cyclic compound biosynthetic processGO:19013622230.011
regulation of neuronal synaptic plasticityGO:004816810.011
muscle cell differentiationGO:00426921390.011
neurotransmitter transportGO:000683620.011
intracellular signal transductionGO:0035556850.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
alternative mrna splicing via spliceosomeGO:000038010.011
positive regulation of cellular processGO:00485222010.011
lamellipodium assemblyGO:003003210.011
positive regulation of muscle cell differentiationGO:005114910.011
regulation of cellular protein catabolic processGO:190336210.011
positive regulation of chromosome organizationGO:200125210.011
regulation of cellular biosynthetic processGO:00313262450.011
epithelial tube morphogenesisGO:00605621480.011
double strand break repair via homologous recombinationGO:000072410.011
mitotic recombinationGO:000631220.011
negative regulation of dna metabolic processGO:005105340.011
spermatid differentiationGO:004851520.011
positive regulation of jnk cascadeGO:004633030.011
single fertilizationGO:000733830.011
regulation of primary metabolic processGO:00800903110.011
cellular response to biotic stimulusGO:007121630.011
regulation of cell communicationGO:00106462320.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
meiosis iGO:000712710.011
cell substrate junction assemblyGO:000704420.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of protein ubiquitinationGO:003139630.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regulation of circadian sleep wake cycle sleepGO:004518710.011
sensory organ morphogenesisGO:00905962000.011
renal tubule morphogenesisGO:006133310.011
response to organic substanceGO:00100331530.011
regulation of myotube differentiationGO:001083020.010
macroautophagyGO:001623610.010
regulation of organelle assemblyGO:190211540.010
intra s dna damage checkpointGO:003157310.010
regulation of protein complex disassemblyGO:004324410.010
cell projection assemblyGO:0030031640.010
cellular response to decreased oxygen levelsGO:003629410.010
lipid homeostasisGO:005508830.010
negative chemotaxisGO:005091910.010
negative regulation of cytoplasmic transportGO:190365020.010
nuclear migrationGO:000709730.010
response to alkaloidGO:004327920.010
cellular carbohydrate metabolic processGO:004426240.010
peptidyl threonine phosphorylationGO:001810710.010
peptidyl threonine modificationGO:001821010.010
oocyte maturationGO:000155640.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
peptide metabolic processGO:000651810.010
regulation of neurotransmitter transportGO:005158810.010
positive regulation of histone modificationGO:003105810.010
response to vitaminGO:003327330.010
regulation of mesenchymal cell proliferationGO:001046410.010
negative regulation of multi organism processGO:004390130.010
response to external biotic stimulusGO:0043207970.010
negative regulation of chemotaxisGO:005092240.010
phasic smooth muscle contractionGO:001482110.010
regulation of cellular component organizationGO:0051128860.010

p2rx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
musculoskeletal system diseaseDOID:1700.017
nervous system diseaseDOID:86300.016
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
immune system diseaseDOID:291400.012
disease of metabolismDOID:001466700.011
cardiovascular system diseaseDOID:128700.010