Danio rerio

14 known processes

p2rx7

purinergic receptor P2X, ligand-gated ion channel, 7

(Aliases: p2xr7)

p2rx7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.085
cellular macromolecule metabolic processGO:00442603910.062
Rat
sensory organ developmentGO:00074233930.062
cellular nitrogen compound metabolic processGO:00346412900.058
neuron differentiationGO:00301823530.054
regulation of establishment of protein localizationGO:007020140.053
Human Rat
central nervous system developmentGO:00074173870.052
signal transductionGO:00071654550.050
Human Rat
larval developmentGO:000216420.050
regulation of protein transportGO:005122330.049
Human Rat
generation of neuronsGO:00486993850.048
nitrogen compound metabolic processGO:00068073190.047
nucleocytoplasmic transportGO:000691340.047
regulation of metabolic processGO:00192223590.046
Rat
cellular aromatic compound metabolic processGO:00067252950.045
cellular protein catabolic processGO:004425740.044
regulation of macromolecule metabolic processGO:00602553170.044
Rat
regulation of gene expressionGO:00104682650.043
regulation of nitrogen compound metabolic processGO:00511712510.043
regulation of cellular metabolic processGO:00313233200.043
Rat
nuclear transportGO:005116940.043
negative regulation of biological processGO:00485193040.043
heterocycle metabolic processGO:00464832900.042
positive regulation of transportGO:005105020.042
Human Rat
amine metabolic processGO:000930820.041
cognitionGO:005089010.040
multicellular organism growthGO:003526440.039
nucleic acid metabolic processGO:00903042440.039
cellular amine metabolic processGO:004410620.038
cellular biosynthetic processGO:00442492860.038
cellular component morphogenesisGO:00329893360.038
gene expressionGO:00104672520.036
single organism metabolic processGO:00447102170.036
regulation of multicellular organismal processGO:00512392770.036
Human Rat
rna metabolic processGO:00160702190.036
nucleobase containing compound metabolic processGO:00061392740.035
digestive system developmentGO:00551232890.035
digestive tract developmentGO:00485652650.035
negative regulation of cellular processGO:00485232830.034
regulation of intracellular protein transportGO:003315730.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
establishment of localizationGO:00512342440.034
regulation of multicellular organism growthGO:004001440.034
cellular nitrogen compound biosynthetic processGO:00442712180.033
establishment of protein localization to organelleGO:007259440.033
cell morphogenesisGO:00009022890.033
protein localization to nucleusGO:003450430.033
regulation of biosynthetic processGO:00098892500.033
head developmentGO:00603223030.032
nuclear importGO:005117030.032
organic cyclic compound metabolic processGO:19013603010.032
regulation of primary metabolic processGO:00800903110.032
Rat
organelle organizationGO:00069962270.032
Rat
modification dependent protein catabolic processGO:001994130.032
positive regulation of cell cycleGO:004578730.031
cell substrate adhesionGO:003158940.031
maintenance of locationGO:005123540.031
brain developmentGO:00074202930.031
nucleobase containing compound biosynthetic processGO:00346542050.031
cellular macromolecule biosynthetic processGO:00346452240.031
single organism nuclear importGO:190259330.031
blood vessel developmentGO:00015682460.030
transportGO:00068102200.030
aromatic compound biosynthetic processGO:00194382170.030
positive regulation of cellular component biogenesisGO:004408930.030
cell part morphogenesisGO:00329902460.030
heart developmentGO:00075073130.030
regulation of cytokine productionGO:000181730.030
Human Rat
protein import into nucleusGO:000660630.030
regulation of protein targetingGO:190353320.030
immune system processGO:00023762410.030
embryonic organ developmentGO:00485683810.029
organic substance biosynthetic processGO:19015762890.029
regulation of rna metabolic processGO:00512522240.029
cell deathGO:00082191210.029
Rat
organonitrogen compound metabolic processGO:1901564740.029
regulation of cytoplasmic transportGO:190364940.028
Human
proteolysis involved in cellular protein catabolic processGO:005160330.028
lipid storageGO:001991510.028
protein importGO:001703830.028
response to carbohydrateGO:000974330.028
negative regulation of protein phosphorylationGO:000193340.028
transcription dna templatedGO:00063511810.028
regulation of multicellular organismal developmentGO:20000262230.028
positive regulation of biological processGO:00485182530.028
Human Rat
nucleic acid templated transcriptionGO:00976591810.028
mitochondrion organizationGO:000700540.027
macromolecule biosynthetic processGO:00090592270.027
regulation of metal ion transportGO:001095940.027
Human Rat
cell surface receptor signaling pathwayGO:00071663250.027
Human Rat
tube morphogenesisGO:00352393490.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
regulation of cellular biosynthetic processGO:00313262450.027
regulation of macromolecule biosynthetic processGO:00105562250.026
regulation of signal transductionGO:00099662250.026
regulation of cellular amino acid metabolic processGO:000652100.026
single organism organelle organizationGO:19025891990.026
blood vessel morphogenesisGO:00485142160.026
protein targeting to nucleusGO:004474430.026
regulation of cell communicationGO:00106462320.026
positive regulation of catabolic processGO:000989640.026
cellular response to external stimulusGO:007149620.026
deathGO:00162651210.026
Rat
morphogenesis of an epitheliumGO:00020093330.026
organic cyclic compound biosynthetic processGO:19013622230.026
oxoacid metabolic processGO:0043436310.026
guanosine containing compound metabolic processGO:190106840.026
meiotic nuclear divisionGO:000712640.025
sensory organ morphogenesisGO:00905962000.025
regulation of cellular amine metabolic processGO:003323800.025
phagocytosisGO:000690930.025
stem cell maintenanceGO:001982740.025
regulation of nucleocytoplasmic transportGO:004682220.025
gtp metabolic processGO:004603940.025
negative regulation of protein transportGO:005122430.025
guanosine containing compound catabolic processGO:190106920.025
regulation of cell activationGO:005086510.025
regulation of protein catabolic processGO:004217610.025
gtp catabolic processGO:000618420.025
small molecule metabolic processGO:0044281770.025
camera type eye developmentGO:00430102220.025
adherens junction organizationGO:003433240.025
regulation of protein localization to nucleusGO:190018020.025
vasculature developmentGO:00019442780.025
regulation of nucleic acid templated transcriptionGO:19035062130.025
proteasomal protein catabolic processGO:001049820.024
eye developmentGO:00016542770.024
cell projection organizationGO:00300302840.024
Human Rat
digestive tract morphogenesisGO:00485462310.024
response to chemicalGO:00422213200.024
Human Rat
positive regulation of cellular catabolic processGO:003133130.024
modification dependent macromolecule catabolic processGO:004363230.024
regulation of nucleoside metabolic processGO:000911820.024
ubiquitin dependent protein catabolic processGO:000651130.024
autophagyGO:000691440.024
regulation of protein import into nucleusGO:004230620.024
stem cell proliferationGO:007208940.024
regulation of cellular ketone metabolic processGO:001056570.024
positive regulation of secretion by cellGO:190353210.024
Human Rat
response to glucoseGO:000974930.023
regulation of signalingGO:00230512350.023
response to hexoseGO:000974630.023
regulation of neural precursor cell proliferationGO:200017730.023
regulation of purine nucleotide catabolic processGO:003312120.023
regulation of bindingGO:005109830.023
angiogenesisGO:00015251580.023
response to drugGO:004249330.023
cellular amino acid metabolic processGO:000652070.023
single organism transportGO:00447652060.023
response to stressGO:00069502630.023
regulation of mrna processingGO:005068430.023
system processGO:00030081850.023
Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
response to monosaccharideGO:003428430.022
extrinsic apoptotic signaling pathwayGO:009719130.022
intracellular signal transductionGO:0035556850.022
single organism membrane fusionGO:004480120.022
organic acid metabolic processGO:0006082310.022
carboxylic acid metabolic processGO:0019752220.022
muscle structure developmentGO:00610611960.022
heterocycle biosynthetic processGO:00181302150.022
neuron developmentGO:00486662620.022
chordate embryonic developmentGO:00430092710.022
lymphocyte proliferationGO:004665110.022
synaptic growth at neuromuscular junctionGO:005112420.022
eye morphogenesisGO:00485921440.022
regulation of biological qualityGO:00650082630.021
Human Rat
programmed cell deathGO:00125011190.021
Rat
protein metabolic processGO:00195381830.021
Rat
regulation of developmental processGO:00507932470.021
protein acetylationGO:000647320.021
cellular component movementGO:00069283350.021
cell matrix adhesionGO:000716040.021
mononuclear cell proliferationGO:003294310.021
regulation of transcription dna templatedGO:00063552130.020
meiotic cell cycle processGO:190304630.020
negative regulation of catabolic processGO:000989530.020
response to abiotic stimulusGO:00096281220.020
female sex differentiationGO:004666040.020
immune system developmentGO:00025201910.020
regulation of erk1 and erk2 cascadeGO:007037240.020
regulation of stem cell proliferationGO:007209120.020
cell projection morphogenesisGO:00488582440.019
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.019
regulation of programmed cell deathGO:00430671010.019
regulation of gtp catabolic processGO:003312420.019
regulation of nucleotide catabolic processGO:003081120.019
transcription from rna polymerase ii promoterGO:0006366800.019
cellular component assemblyGO:00226071700.019
Human Rat
hemopoiesisGO:00300971830.019
rna biosynthetic processGO:00327741810.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
regulation of cell deathGO:00109411030.019
Rat
erk1 and erk2 cascadeGO:007037140.019
glucose homeostasisGO:004259310.019
cellular component biogenesisGO:00440851780.019
Human Rat
cytokinesisGO:000091030.019
regulation of synapse assemblyGO:005196330.018
regulation of synapse organizationGO:005080730.018
positive regulation of cellular amine metabolic processGO:003324000.018
regulation of epithelial cell proliferationGO:005067830.018
exocytosisGO:000688710.018
cilium morphogenesisGO:0060271850.018
regulation of rna biosynthetic processGO:20011412130.018
cellular response to extracellular stimulusGO:003166820.018
atp catabolic processGO:000620040.018
cellular ketone metabolic processGO:0042180110.018
positive regulation of cellular processGO:00485222010.018
Human Rat
membrane fusionGO:006102520.018
regulation of response to stimulusGO:00485832690.018
positive regulation of cytokine productionGO:000181920.018
Human Rat
leukocyte proliferationGO:007066110.018
positive regulation of i kappab kinase nf kappab signalingGO:004312330.018
rna localizationGO:000640340.018
negative regulation of cytoplasmic transportGO:190365020.018
negative regulation of metabolic processGO:0009892860.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
embryo development ending in birth or egg hatchingGO:00097922710.018
positive regulation of nucleoside metabolic processGO:004597910.018
negative regulation of cytokine productionGO:000181810.018
cellular carbohydrate metabolic processGO:004426240.018
regulation of apoptotic processGO:0042981980.018
locomotor rhythmGO:004547530.018
regulation of gtpase activityGO:004308720.018
cellular protein metabolic processGO:00442671290.017
Rat
cellular response to nutrient levelsGO:003166920.017
apoptotic processGO:00069151160.017
Rat
negative regulation of gene expressionGO:0010629650.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
regulation of reproductive processGO:200024140.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
cellular protein modification processGO:00064641000.017
Rat
nucleoside monophosphate catabolic processGO:000912540.017
ribonucleoside monophosphate catabolic processGO:000915840.017
cilium organizationGO:0044782710.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
peptidyl serine phosphorylationGO:001810510.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
biosynthetic processGO:00090582940.017
purine nucleoside monophosphate catabolic processGO:000912840.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
carbohydrate homeostasisGO:003350010.017
cell morphogenesis involved in differentiationGO:00009041950.017
nuclear exportGO:005116810.017
regulation of protein ubiquitinationGO:003139630.016
i kappab kinase nf kappab signalingGO:000724940.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
regulation of protein complex assemblyGO:004325430.016
positive regulation of cell activationGO:005086710.016
development of primary female sexual characteristicsGO:004654540.016
cellular response to chemical stimulusGO:00708871570.016
negative regulation of macromolecule metabolic processGO:0010605760.016
positive regulation of nucleotide catabolic processGO:003081310.016
negative regulation of cellular metabolic processGO:0031324770.016
female gonad developmentGO:000858540.016
g1 s transition of mitotic cell cycleGO:000008210.016
negative regulation of mapk cascadeGO:004340940.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
embryonic organ morphogenesisGO:00485622740.016
negative regulation of kinase activityGO:003367340.016
compound eye developmentGO:004874920.016
protein localization to plasma membraneGO:007265910.016
peptidyl lysine acetylationGO:001839420.016
regulation of cell differentiationGO:00455951420.016
protein secretionGO:000930610.016
Human Rat
regionalizationGO:00030022740.015
response to nutrientGO:000758430.015
camera type eye morphogenesisGO:00485931080.015
positive regulation of neuron apoptotic processGO:004352510.015
cell cycle g1 s phase transitionGO:004484310.015
internal peptidyl lysine acetylationGO:001839320.015
germ line stem cell maintenanceGO:003071820.015
post embryonic organ developmentGO:004856940.015
negative regulation of cellular catabolic processGO:003133030.015
negative regulation of protein kinase activityGO:000646940.015
retina morphogenesis in camera type eyeGO:0060042790.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
regulation of dna replicationGO:000627530.015
positive regulation of protein complex assemblyGO:003133420.015
peptide transportGO:001583310.015
response to uvGO:000941130.015
lipid homeostasisGO:005508830.015
positive regulation of cytoskeleton organizationGO:005149530.015
Rat
response to alkaloidGO:004327920.015
positive regulation of secretionGO:005104710.015
Human Rat
internal protein amino acid acetylationGO:000647520.015
antimicrobial humoral responseGO:001973020.015
peptidyl serine modificationGO:001820920.015
regulation of cellular protein catabolic processGO:190336210.015
adult behaviorGO:003053420.015
response to external stimulusGO:00096052640.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
neurological system processGO:0050877620.015
Rat
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
positive regulation of neuron deathGO:190121610.015
cellular response to hypoxiaGO:007145610.014
regulation of reactive oxygen species metabolic processGO:200037720.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
cellular response to starvationGO:000926710.014
cellular component disassemblyGO:002241110.014
fertilizationGO:000956630.014
regulation of production of molecular mediator of immune responseGO:000270010.014
specification of symmetryGO:00097992040.014
cell migrationGO:00164772370.014
protein modification processGO:00362111000.014
Rat
positive regulation of apoptotic signaling pathwayGO:200123510.014
single organism localizationGO:19025782250.014
cytoskeleton dependent cytokinesisGO:006164030.014
protein dephosphorylationGO:000647030.014
phosphate containing compound metabolic processGO:00067961080.014
Rat
somatic muscle developmentGO:000752540.014
negative regulation of intracellular protein transportGO:009031730.014
meiotic chromosome segregationGO:004513230.014
positive regulation of gtpase activityGO:004354710.014
positive regulation of gtp catabolic processGO:003312610.013
positive regulation of translationGO:004572710.013
positive regulation of immune effector processGO:000269930.013
gastrulationGO:00073692080.013
dorsal ventral pattern formationGO:00099531250.013
negative regulation of secretionGO:005104820.013
secondary metabolic processGO:001974830.013
spermatid developmentGO:000728620.013
primary neural tube formationGO:001402010.013
response to organic substanceGO:00100331530.013
Human Rat
skeletal system developmentGO:00015011810.013
production of molecular mediator of immune responseGO:000244020.013
negative regulation of secretion by cellGO:190353120.013
protein targeting to membraneGO:000661210.013
monocyte differentiationGO:003022420.013
regulation of blood pressureGO:000821710.013
microtubule organizing center organizationGO:003102310.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
cellular amide metabolic processGO:004360340.013
cell proliferationGO:0008283800.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
cellular response to oxygen levelsGO:007145310.013
regulation of autophagyGO:001050630.013
protein acylationGO:004354330.013
retina development in camera type eyeGO:00600411460.013
b cell activationGO:004211320.013
regulation of transporter activityGO:003240920.013
negative regulation of intracellular transportGO:003238730.013
inner ear developmentGO:00488391260.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
regulation of cell substrate adhesionGO:001081010.013
regulation of jak stat cascadeGO:004642530.013
determination of left right symmetryGO:00073681790.013
phosphorus metabolic processGO:00067931090.013
Rat
localization of cellGO:00516742440.013
developmental programmed cell deathGO:001062340.013
positive regulation of cell adhesionGO:004578510.013
neuron projection developmentGO:00311751800.013
cellular response to radiationGO:007147840.013
spermatid differentiationGO:004851520.013
determination of bilateral symmetryGO:00098552040.012
macromolecule modificationGO:00434121110.012
Rat
regulation of calcium ion transportGO:005192420.012
Human
phosphorylationGO:0016310690.012
Rat
myeloid cell differentiationGO:0030099860.012
organelle fusionGO:004828430.012
b cell differentiationGO:003018310.012
regulation of meiotic cell cycleGO:005144510.012
neuroblast proliferationGO:000740520.012
epithelial tube morphogenesisGO:00605621480.012
tissue remodelingGO:004877140.012
protein homooligomerizationGO:005126030.012
rna 3 end processingGO:003112320.012
toll like receptor signaling pathwayGO:000222440.012
regulation of dendrite developmentGO:005077330.012
ear developmentGO:00435831270.012
positive regulation of stress activated mapk cascadeGO:003287430.012
positive regulation of map kinase activityGO:004340630.012
cell substrate junction assemblyGO:000704420.012
positive regulation of dna metabolic processGO:005105410.012
sensory perception of painGO:001923310.012
regulation of cell shapeGO:000836010.012
negative regulation of response to stimulusGO:00485851040.012
neuron projection morphogenesisGO:00488121610.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
endosomal transportGO:001619720.012
growthGO:00400071740.012
interspecies interaction between organismsGO:004441940.012
positive regulation of cellular metabolic processGO:0031325940.012
Rat
response to oxygen containing compoundGO:1901700550.012
Human Rat
erythrocyte homeostasisGO:0034101550.012
centrosome organizationGO:005129710.012
negative regulation of cell deathGO:0060548600.012
locomotionGO:00400113130.012
stem cell differentiationGO:00488631170.012
cell motilityGO:00488702440.012
negative regulation of dna metabolic processGO:005105340.012
positive regulation of epithelial cell proliferationGO:005067910.012
developmental growthGO:00485891660.011
negative regulation of defense responseGO:003134820.011
cilium assemblyGO:0042384580.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
ras protein signal transductionGO:000726570.011
regulation of cell developmentGO:00602841000.011
negative regulation of protein import into nucleusGO:004230820.011
gland developmentGO:00487321430.011
stem cell divisionGO:001714510.011
mitotic dna integrity checkpointGO:004477440.011
regulation of localizationGO:00328791040.011
Human Rat
convergent extensionGO:00600261180.011
protein stabilizationGO:005082120.011
viral processGO:001603210.011
negative regulation of protein localization to nucleusGO:190018120.011
multi organism cellular processGO:004476420.011
cellular response to organic substanceGO:00713101050.011
neuron neuron synaptic transmissionGO:000727010.011
regulation of mrna splicing via spliceosomeGO:004802430.011
membrane invaginationGO:001032410.011
regulation of circadian rhythmGO:004275240.011
cellular response to lipopolysaccharideGO:007122230.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
centrosome cycleGO:000709810.011
phagocytosis engulfmentGO:000691110.011
cellular response to biotic stimulusGO:007121630.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
cation transportGO:0006812810.011
embryonic hemopoiesisGO:0035162530.011
positive regulation of stem cell proliferationGO:200064810.011
negative regulation of cell communicationGO:0010648960.011
regulation of stem cell differentiationGO:200073640.011
tube closureGO:006060610.011
amino acid transportGO:000686520.011
positive regulation of jnk cascadeGO:004633030.011
mitotic dna damage checkpointGO:004477340.011
regulation of inflammatory responseGO:005072720.011
regulation of ion transmembrane transporter activityGO:003241220.011
regulation of anatomical structure morphogenesisGO:00226031300.011
regulation of cell matrix adhesionGO:000195210.011
ovulation cycleGO:004269820.011
signal transduction in absence of ligandGO:003803410.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
erythrocyte differentiationGO:0030218540.011
positive regulation of myeloid cell differentiationGO:004563920.011
hormone transportGO:000991420.011
small gtpase mediated signal transductionGO:000726480.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
regulation of response to biotic stimulusGO:000283120.010
response to corticosteroidGO:003196010.010
response to endogenous stimulusGO:0009719830.010
Human Rat
startle responseGO:000196440.010
regulation of postsynaptic membrane potentialGO:006007810.010
cellular respirationGO:004533330.010
peptidyl threonine phosphorylationGO:001810710.010
regulation of sodium ion transportGO:000202820.010
Rat
hindbrain developmentGO:0030902910.010
b cell mediated immunityGO:001972430.010
regulation of transmembrane transporter activityGO:002289820.010
cellular response to molecule of bacterial originGO:007121930.010
monoamine transportGO:001584410.010
negative regulation of map kinase activityGO:004340720.010
protein complex disassemblyGO:004324110.010
somite developmentGO:0061053960.010
macromolecular complex disassemblyGO:003298410.010
cellular response to decreased oxygen levelsGO:003629410.010
phosphatidylinositol mediated signalingGO:004801520.010
regulation of cellular component organizationGO:0051128860.010
Rat
somatic stem cell maintenanceGO:003501910.010
regulation of dna templated transcription in response to stressGO:004362000.010
chemosensory behaviorGO:000763510.010
cell cycle arrestGO:000705010.010
striated muscle tissue developmentGO:00147061100.010
muscle cell differentiationGO:00426921390.010
immunoglobulin mediated immune responseGO:001606430.010
cellular component assembly involved in morphogenesisGO:00109271070.010
negative regulation of myeloid cell differentiationGO:004563810.010

p2rx7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.017
nervous system diseaseDOID:86300.017
organ system cancerDOID:005068600.016
musculoskeletal system diseaseDOID:1700.016
disease of metabolismDOID:001466700.014
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
immune system diseaseDOID:291400.011