Danio rerio

0 known processes

actn3a

actinin alpha 3a

(Aliases: actn3,ACTN2,zgc:63559,actnl,MGC63559)

actn3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal muscle tissue developmentGO:0007519670.997
Zebrafish
skeletal muscle fiber developmentGO:0048741350.995
Zebrafish
skeletal muscle organ developmentGO:0060538780.994
Zebrafish
myotube cell developmentGO:0014904350.984
Zebrafish
muscle cell developmentGO:00550011150.966
Zebrafish Fly
voluntary skeletal muscle contractionGO:000301040.942
nucleobase containing compound metabolic processGO:00061392740.921
myofibril assemblyGO:0030239480.920
Zebrafish Fly
muscle fiber developmentGO:0048747520.917
Zebrafish
purine ribonucleoside monophosphate catabolic processGO:000916940.890
muscle organ developmentGO:00075171010.868
Zebrafish
chordate embryonic developmentGO:00430092710.859
striated muscle cell developmentGO:00550021080.840
Zebrafish Fly
skeletal myofibril assemblyGO:001486670.834
striated muscle tissue developmentGO:00147061100.833
Zebrafish
embryo development ending in birth or egg hatchingGO:00097922710.753
Worm
muscle structure developmentGO:00610611960.698
Zebrafish Fly
locomotionGO:00400113130.638
skeletal muscle thin filament assemblyGO:003024040.620
muscle tissue developmentGO:00605371100.598
Zebrafish
larval developmentGO:000216420.594
skeletal muscle myosin thick filament assemblyGO:003024150.575
striated muscle cell differentiationGO:00511461290.563
Zebrafish Fly
heterocycle biosynthetic processGO:00181302150.555
cellular aromatic compound metabolic processGO:00067252950.530
nucleic acid templated transcriptionGO:00976591810.529
cell migrationGO:00164772370.525
regulation of sarcomere organizationGO:006029720.522
regulation of biological qualityGO:00650082630.486
twitch skeletal muscle contractionGO:001472140.470
adult behaviorGO:003053420.460
Fly
organic cyclic compound metabolic processGO:19013603010.446
myotube differentiationGO:0014902450.438
Zebrafish
nucleoside monophosphate catabolic processGO:000912540.425
aromatic compound biosynthetic processGO:00194382170.417
nitrogen compound metabolic processGO:00068073190.406
heart developmentGO:00075073130.373
Zebrafish
ion transmembrane transportGO:0034220910.336
heterocycle metabolic processGO:00464832900.333
anterior posterior pattern specificationGO:00099521520.326
cellular component movementGO:00069283350.326
actin filament based movementGO:003004810.324
blood circulationGO:0008015870.318
muscle cell differentiationGO:00426921390.318
Zebrafish Fly
skeletal muscle contractionGO:000300950.316
regulation of nucleobase containing compound metabolic processGO:00192192500.309
somitogenesisGO:0001756870.299
cell motilityGO:00488702440.298
maintenance of locationGO:005123540.297
cellular biosynthetic processGO:00442492860.297
biosynthetic processGO:00090582940.292
purine nucleoside monophosphate catabolic processGO:000912840.284
regulation of multicellular organismal developmentGO:20000262230.280
signal transductionGO:00071654550.273
embryonic organ morphogenesisGO:00485622740.266
organic cyclic compound biosynthetic processGO:19013622230.254
muscle system processGO:0003012200.243
Mouse
somite developmentGO:0061053960.242
heart contractionGO:0060047710.228
cognitionGO:005089010.227
transcription from rna polymerase ii promoterGO:0006366800.227
actin filament based processGO:0030029640.216
Zebrafish Fly
transmembrane transportGO:00550851200.215
regulation of cellular metabolic processGO:00313233200.202
embryonic organ developmentGO:00485683810.201
behaviorGO:0007610740.199
Fly
regulation of rna metabolic processGO:00512522240.183
regulation of developmental processGO:00507932470.180
slow twitch skeletal muscle fiber contractionGO:003144430.174
localization of cellGO:00516742440.174
cellular nitrogen compound metabolic processGO:00346412900.169
synaptic transmission cholinergicGO:000727140.162
regulation of cellular macromolecule biosynthetic processGO:20001122220.160
organic substance biosynthetic processGO:19015762890.154
regulation of cellular biosynthetic processGO:00313262450.151
regulation of multicellular organismal processGO:00512392770.150
ribonucleoside monophosphate catabolic processGO:000915840.149
rna metabolic processGO:00160702190.147
regulation of wound healingGO:006104120.147
protein stabilizationGO:005082120.145
multicellular organismal reproductive processGO:0048609350.145
regulation of primary metabolic processGO:00800903110.139
organonitrogen compound metabolic processGO:1901564740.138
muscle contractionGO:0006936180.137
Mouse
response to activityGO:0014823140.137
regulation of macromolecule metabolic processGO:00602553170.132
rna biosynthetic processGO:00327741810.128
cell projection morphogenesisGO:00488582440.127
regulation of organelle assemblyGO:190211540.122
oocyte developmentGO:0048599140.118
regulation of nitrogen compound metabolic processGO:00511712510.108
muscle cell cellular homeostasisGO:004671650.108
system processGO:00030081850.108
Mouse
cell projection organizationGO:00300302840.106
digestive system developmentGO:00551232890.105
regulation of muscle contractionGO:000693730.105
somite specificationGO:0001757120.097
regulation of macromolecule biosynthetic processGO:00105562250.097
cellular nitrogen compound biosynthetic processGO:00442712180.094
establishment of localizationGO:00512342440.094
positive regulation of wound healingGO:009030310.093
multi organism reproductive processGO:0044703360.093
inorganic cation transmembrane transportGO:0098662500.093
segmentationGO:0035282970.093
atp catabolic processGO:000620040.092
nucleic acid metabolic processGO:00903042440.089
cellular ion homeostasisGO:0006873170.088
transcription dna templatedGO:00063511810.087
mesenchyme developmentGO:00604851270.087
regulation of metabolic processGO:00192223590.085
cardiac muscle fiber developmentGO:004873930.081
regulation of cell developmentGO:00602841000.081
cell morphogenesis involved in differentiationGO:00009041950.080
vasculature developmentGO:00019442780.079
regulation of biosynthetic processGO:00098892500.079
macromolecule biosynthetic processGO:00090592270.079
cardiac muscle myosin thick filament assemblyGO:007169010.077
regulation of gene expressionGO:00104682650.076
multicellular organism growthGO:003526440.076
nucleobase containing compound biosynthetic processGO:00346542050.075
catabolic processGO:0009056320.075
Worm
ventricular cardiac muscle tissue morphogenesisGO:005501020.074
sarcomere organizationGO:0045214260.074
Zebrafish Fly
multicellular organism reproductionGO:0032504350.072
embryonic cranial skeleton morphogenesisGO:0048701900.071
sequestering of metal ionGO:005123830.071
neuroblast differentiationGO:001401610.071
embryonic pattern specificationGO:0009880440.070
regulation of nucleic acid templated transcriptionGO:19035062130.069
cellular component morphogenesisGO:00329893360.067
Zebrafish Fly
axonogenesisGO:00074091520.064
organic cyclic compound catabolic processGO:1901361150.064
sensory organ developmentGO:00074233930.062
Zebrafish
organelle assemblyGO:00709251100.061
Zebrafish Fly
cellular macromolecule metabolic processGO:00442603910.060
gene expressionGO:00104672520.059
intracellular signal transductionGO:0035556850.058
single organism reproductive processGO:0044702400.058
brain developmentGO:00074202930.058
ventricular cardiac muscle tissue developmentGO:000322930.057
organelle organizationGO:00069962270.056
Zebrafish Worm Fly
heart loopingGO:0001947940.055
digestive tract developmentGO:00485652650.054
neuron differentiationGO:00301823530.054
organophosphate metabolic processGO:0019637370.054
cell migration involved in gastrulationGO:0042074790.053
negative regulation of biological processGO:00485193040.052
multi organism processGO:00517041340.051
neuron developmentGO:00486662620.051
cellular homeostasisGO:0019725260.051
striated muscle myosin thick filament assemblyGO:007168860.051
generation of neuronsGO:00486993850.051
musculoskeletal movementGO:005088180.050
regulation of transcription from rna polymerase ii promoterGO:00063571140.050
cell morphogenesis involved in neuron differentiationGO:00486671630.049
small molecule metabolic processGO:0044281770.049
regulation of transcription dna templatedGO:00063552130.049
regulation of cell differentiationGO:00455951420.048
cytosolic calcium ion transportGO:006040130.047
regulation of heart growthGO:006042020.046
cell agingGO:000756920.046
lipid storageGO:001991510.046
regulation of response to stimulusGO:00485832690.046
regionalizationGO:00030022740.045
extrinsic apoptotic signaling pathwayGO:009719130.045
regulation of nucleoside metabolic processGO:000911820.045
somatic muscle developmentGO:000752540.044
homeostatic processGO:00425921420.044
morphogenesis of an epitheliumGO:00020093330.043
epithelial cell differentiationGO:00308551160.043
phosphorus metabolic processGO:00067931090.043
axon developmentGO:00615641660.043
response to chemicalGO:00422213200.043
protein metabolic processGO:00195381830.042
Worm
hemopoiesisGO:00300971830.041
regulation of metal ion transportGO:001095940.041
positive regulation of nucleic acid templated transcriptionGO:1903508570.041
chemotaxisGO:00069351040.040
striated muscle contractionGO:0006941120.040
inositol lipid mediated signalingGO:004801720.040
embryonic viscerocranium morphogenesisGO:0048703520.039
cellular calcium ion homeostasisGO:0006874130.039
locomotory behaviorGO:0007626340.039
Fly
single organism transportGO:00447652060.038
regulation of mrna splicing via spliceosomeGO:004802430.038
taxisGO:00423301090.038
regulation of rna biosynthetic processGO:20011412130.038
response to external stimulusGO:00096052640.038
cell substrate adherens junction assemblyGO:000704510.037
carbohydrate derivative metabolic processGO:1901135610.036
positive regulation of macromolecule metabolic processGO:0010604930.036
ameboidal type cell migrationGO:00016671430.035
positive regulation of gene expressionGO:0010628710.035
central nervous system developmentGO:00074173870.035
positive regulation of biological processGO:00485182530.034
blood vessel morphogenesisGO:00485142160.034
cation homeostasisGO:0055080330.034
multicellular organismal movementGO:005087980.034
metal ion transportGO:0030001580.034
regulation of ion transmembrane transporter activityGO:003241220.033
cytoskeleton dependent cytokinesisGO:006164030.033
convergent extension involved in gastrulationGO:0060027710.032
adherens junction assemblyGO:003433310.031
cation transportGO:0006812810.031
ribonucleotide metabolic processGO:0009259270.031
regulation of nucleotide catabolic processGO:003081120.031
positive regulation of multicellular organismal processGO:0051240520.031
growthGO:00400071740.030
developmental process involved in reproductionGO:0003006270.030
mitochondrion organizationGO:000700540.030
regulation of multicellular organism growthGO:004001440.030
cardiac muscle cell differentiationGO:0055007300.030
ion transportGO:00068111140.030
peptidyl lysine methylationGO:001802230.030
microtubule organizing center organizationGO:003102310.030
single organism biosynthetic processGO:0044711710.029
organelle fissionGO:0048285230.029
Worm
regulation of phosphorus metabolic processGO:0051174430.029
cellular component assembly involved in morphogenesisGO:00109271070.029
Zebrafish Fly
cell part morphogenesisGO:00329902460.028
histone h3 k4 methylationGO:005156820.028
cellular metal ion homeostasisGO:0006875160.028
regulation of extrinsic apoptotic signaling pathwayGO:200123630.028
ras protein signal transductionGO:000726570.027
rna modificationGO:000945120.027
positive regulation of nucleobase containing compound metabolic processGO:0045935690.026
organic substance catabolic processGO:1901575280.026
Worm
growth plate cartilage developmentGO:000341720.026
anatomical structure homeostasisGO:0060249360.025
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.025
regulation of calcium ion transportGO:005192420.025
metal ion homeostasisGO:0055065260.025
cell fate commitmentGO:0045165990.025
reproductionGO:0000003400.025
growth plate cartilage morphogenesisGO:000342210.025
carboxylic acid metabolic processGO:0019752220.025
single organism behaviorGO:0044708240.024
Fly
cardiac muscle cell developmentGO:0055013200.024
purine ribonucleotide metabolic processGO:0009150270.024
nucleoside phosphate metabolic processGO:0006753280.024
cytokinetic processGO:003250620.024
cardiac muscle tissue developmentGO:0048738480.024
cell substrate junction assemblyGO:000704420.023
ribonucleoside monophosphate metabolic processGO:000916150.023
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.023
digestive tract morphogenesisGO:00485462310.023
purine ribonucleoside monophosphate metabolic processGO:000916750.023
blood vessel developmentGO:00015682460.022
single organism organelle organizationGO:19025891990.022
Zebrafish Worm Fly
regulation of transmembrane transporter activityGO:002289820.022
gastrulationGO:00073692080.022
single organism localizationGO:19025782250.022
renal tubule morphogenesisGO:006133310.022
positive regulation of nitrogen compound metabolic processGO:0051173690.022
regulation of reproductive processGO:200024140.021
germ cell developmentGO:0007281220.021
cellular cation homeostasisGO:0030003170.021
oocyte differentiationGO:0009994140.021
negative regulation of cell deathGO:0060548600.021
iron ion homeostasisGO:005507240.021
regulation of signal transductionGO:00099662250.020
cellular component biogenesisGO:00440851780.020
Zebrafish Fly
regulation of neurogenesisGO:0050767870.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.020
cytokinesisGO:000091030.020
regulation of mrna processingGO:005068430.020
regulation of endothelial cell proliferationGO:000193610.020
cell death in response to oxidative stressGO:003647320.020
nucleobase containing small molecule metabolic processGO:0055086320.020
tube morphogenesisGO:00352393490.020
sarcomerogenesisGO:004876940.020
skeletal system developmentGO:00015011810.020
macromolecule catabolic processGO:0009057150.019
Worm
neuroblast fate commitmentGO:001401710.019
cellular respirationGO:004533330.019
regulation of behaviorGO:0050795240.019
calcium ion transport into cytosolGO:006040230.019
epithelial tube morphogenesisGO:00605621480.019
response to stressGO:00069502630.019
transportGO:00068102200.019
immune system developmentGO:00025201910.018
angiogenesisGO:00015251580.018
skeletal system morphogenesisGO:00487051020.018
regulation of circadian rhythmGO:004275240.018
purine containing compound metabolic processGO:0072521290.018
regulation of molecular functionGO:0065009700.018
macromolecular complex subunit organizationGO:0043933740.018
immune system processGO:00023762410.018
actin cytoskeleton organizationGO:0030036630.018
Zebrafish Fly
regulation of membrane potentialGO:0042391230.017
developmental growthGO:00485891660.017
endothelial cell proliferationGO:0001935110.017
regulation of cellular response to oxidative stressGO:190040720.017
regulation of establishment of planar polarityGO:009017540.016
regulation of organ growthGO:004662030.016
negative regulation of apoptotic processGO:0043066550.016
regulation of skeletal muscle fiber developmentGO:004874220.016
mitotic cell cycleGO:0000278640.016
Worm
agingGO:000756820.016
response to oxidative stressGO:0006979110.016
positive regulation of transportGO:005105020.016
regulation of transporter activityGO:003240920.016
regulation of transmembrane transportGO:0034762180.016
regulation of purine nucleotide catabolic processGO:003312120.016
negative regulation of programmed cell deathGO:0043069580.016
positive regulation of rna biosynthetic processGO:1902680570.016
potassium ion transmembrane transportGO:0071805100.016
mitotic g2 m transition checkpointGO:004481830.016
regulation of filopodium assemblyGO:005148920.016
determination of left right symmetryGO:00073681790.016
stem cell differentiationGO:00488631170.016
regulation of photoreceptor cell differentiationGO:004653220.016
cardiac atrium morphogenesisGO:000320920.015
positive regulation of metabolic processGO:00098931080.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.015
embryonic skeletal system developmentGO:0048706970.015
appendage developmentGO:0048736800.015
regulation of cell communicationGO:00106462320.015
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.015
lipid homeostasisGO:005508830.015
ear developmentGO:00435831270.015
cell surface receptor signaling pathwayGO:00071663250.014
dna catabolic processGO:000630810.014
regulation of skeletal muscle tissue developmentGO:004864140.014
regulation of tube sizeGO:003515020.014
positive regulation of biosynthetic processGO:0009891680.014
centrosome organizationGO:005129710.014
nucleoside monophosphate metabolic processGO:000912360.014
phosphate containing compound metabolic processGO:00067961080.014
negative regulation of sequestering of calcium ionGO:005128340.014
regulation of cell activationGO:005086510.014
superoxide metabolic processGO:000680120.014
larval behaviorGO:003053750.014
meiotic cell cycle processGO:190304630.014
regulation of striated muscle contractionGO:000694220.014
cardiac atrium developmentGO:000323040.014
myosin filament assemblyGO:003103460.014
regulation of blood vessel sizeGO:005088020.013
cellular amine metabolic processGO:004410620.013
regulation of catalytic activityGO:0050790550.013
convergent extensionGO:00600261180.013
ribosomal small subunit biogenesisGO:004227420.013
cell cycle g2 m phase transitionGO:004483940.013
cellular component assemblyGO:00226071700.013
Zebrafish Fly
posttranscriptional regulation of gene expressionGO:0010608140.013
myosin filament organizationGO:003103360.013
cell morphogenesisGO:00009022890.013
nephron epithelium morphogenesisGO:007208810.013
response to nutrientGO:000758430.013
cellular amino acid biosynthetic processGO:000865220.013
cellular divalent inorganic cation homeostasisGO:0072503130.013
organ formationGO:0048645170.013
sleepGO:003043110.013
response to extracellular stimulusGO:0009991100.013
purine nucleoside monophosphate metabolic processGO:000912650.013
negative regulation of protein phosphorylationGO:000193340.013
g2 m transition of mitotic cell cycleGO:000008640.012
reactive oxygen species biosynthetic processGO:190340910.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
embryonic skeletal system morphogenesisGO:0048704930.012
positive regulation of cellular biosynthetic processGO:0031328680.012
regulation of nervous system developmentGO:0051960900.012
connective tissue developmentGO:0061448990.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
gamete generationGO:0007276330.012
cellular macromolecule biosynthetic processGO:00346452240.012
developmental programmed cell deathGO:001062340.012
cell maturationGO:0048469230.012
regulation of purine nucleotide metabolic processGO:1900542170.012
potassium ion transportGO:0006813100.012
cell cycleGO:0007049930.012
Worm
positive regulation of rna metabolic processGO:0051254590.012
removal of superoxide radicalsGO:001943020.011
positive regulation of developmental processGO:0051094500.011
regulation of alcohol biosynthetic processGO:190293010.011
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.011
regulation of response to oxidative stressGO:190288220.011
heart morphogenesisGO:00030071560.011
membrane repolarizationGO:008600920.011
head developmentGO:00603223030.011
autophagyGO:000691440.011
regulation of bindingGO:005109830.011
developmental maturationGO:0021700340.011
oogenesisGO:0048477140.011
positive regulation of cellular metabolic processGO:0031325940.011
notochord developmentGO:0030903540.011
mitotic cell cycle processGO:1903047480.011
Worm
anterior commissure morphogenesisGO:002196030.011
regulation of protein bindingGO:004339330.011
organic acid metabolic processGO:0006082310.011
negative regulation of developmental processGO:0051093650.011
deathGO:00162651210.011
positive regulation of cellular amine metabolic processGO:003324000.011
skin developmentGO:0043588540.010
stem cell fate commitmentGO:004886510.010
negative regulation of gene expressionGO:0010629650.010
regulation of blood circulationGO:1903522320.010
reproductive processGO:0022414400.010
amine metabolic processGO:000930820.010

actn3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.182
inherited metabolic disorderDOID:65500.182
mitochondrial metabolism diseaseDOID:70000.182
cardiovascular system diseaseDOID:128700.075
disease of anatomical entityDOID:700.075
intrinsic cardiomyopathyDOID:006003600.075
muscle tissue diseaseDOID:6600.075
musculoskeletal system diseaseDOID:1700.075
heart diseaseDOID:11400.075
muscular diseaseDOID:008000000.075
cardiomyopathyDOID:005070000.075
myopathyDOID:42300.075
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
organ system cancerDOID:005068600.012
endocrine gland cancerDOID:17000.012