Danio rerio

79 known processes

casp8

caspase 8, apoptosis-related cysteine peptidase

(Aliases: caspase-8,MGC92075,zgc:92075)

casp8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.216
Human Mouse
regulation of cell communicationGO:00106462320.203
Human Mouse
positive regulation of cellular processGO:00485222010.171
regulation of signal transductionGO:00099662250.169
Human Mouse
cellular nitrogen compound metabolic processGO:00346412900.166
programmed cell deathGO:00125011190.160
cell migrationGO:00164772370.136
regulation of metabolic processGO:00192223590.131
transcription dna templatedGO:00063511810.128
cellular macromolecule metabolic processGO:00442603910.124
regulation of apoptotic processGO:0042981980.123
cell deathGO:00082191210.120
rna biosynthetic processGO:00327741810.118
regulation of cellular metabolic processGO:00313233200.118
heterocycle metabolic processGO:00464832900.116
apoptotic processGO:00069151160.116
deathGO:00162651210.112
chordate embryonic developmentGO:00430092710.108
single organism metabolic processGO:00447102170.106
immune system processGO:00023762410.103
protein metabolic processGO:00195381830.103
response to other organismGO:0051707970.102
regulation of nucleic acid templated transcriptionGO:19035062130.101
response to organic substanceGO:00100331530.100
regulation of macromolecule metabolic processGO:00602553170.100
heterocycle biosynthetic processGO:00181302150.096
regulation of programmed cell deathGO:00430671010.095
regulation of signalingGO:00230512350.094
Human Mouse
regulation of cell deathGO:00109411030.093
positive regulation of cell deathGO:0010942290.093
regulation of cellular biosynthetic processGO:00313262450.089
response to chemicalGO:00422213200.089
cellular macromolecule biosynthetic processGO:00346452240.088
nitrogen compound metabolic processGO:00068073190.088
hematopoietic or lymphoid organ developmentGO:00485341910.087
regulation of cellular macromolecule biosynthetic processGO:20001122220.086
negative regulation of cellular processGO:00485232830.085
Human Mouse
stem cell proliferationGO:007208940.084
positive regulation of biological processGO:00485182530.084
regulation of transcription dna templatedGO:00063552130.083
regulation of biosynthetic processGO:00098892500.083
response to external stimulusGO:00096052640.081
cellular aromatic compound metabolic processGO:00067252950.080
mitochondrion organizationGO:000700540.080
cellular protein catabolic processGO:004425740.079
regulation of response to stimulusGO:00485832690.079
Human Mouse
modification dependent macromolecule catabolic processGO:004363230.079
proteasomal protein catabolic processGO:001049820.079
hemopoiesisGO:00300971830.079
gene expressionGO:00104672520.075
positive regulation of transportGO:005105020.075
regulation of nitrogen compound metabolic processGO:00511712510.074
organic cyclic compound metabolic processGO:19013603010.074
morphogenesis of an epitheliumGO:00020093330.074
nucleobase containing compound metabolic processGO:00061392740.074
nuclear transportGO:005116940.074
cellular response to chemical stimulusGO:00708871570.072
response to virusGO:0009615210.072
extrinsic apoptotic signaling pathwayGO:009719130.071
Human Mouse
ubiquitin dependent protein catabolic processGO:000651130.071
regulation of macromolecule biosynthetic processGO:00105562250.071
cellular protein metabolic processGO:00442671290.070
regulation of stem cell differentiationGO:200073640.066
heart morphogenesisGO:00030071560.065
regulation of multicellular organismal processGO:00512392770.065
neuron differentiationGO:00301823530.064
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.063
tube morphogenesisGO:00352393490.061
positive regulation of cytokine productionGO:000181920.060
segmentationGO:0035282970.060
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.059
positive regulation of neuron deathGO:190121610.059
single organism membrane fusionGO:004480120.059
cell surface receptor signaling pathwayGO:00071663250.059
Human Mouse
response to biotic stimulusGO:0009607970.058
leukocyte proliferationGO:007066110.058
regulation of mitochondrion organizationGO:001082110.057
brain developmentGO:00074202930.057
regulation of cytokine productionGO:000181730.057
regulation of cell shapeGO:000836010.057
lipid storageGO:001991510.056
response to antibioticGO:004667710.056
regulation of nucleobase containing compound metabolic processGO:00192192500.055
embryonic organ developmentGO:00485683810.055
cell projection morphogenesisGO:00488582440.055
heart developmentGO:00075073130.055
positive regulation of neuron apoptotic processGO:004352510.054
cellular biosynthetic processGO:00442492860.054
response to external biotic stimulusGO:0043207970.054
regulation of rna metabolic processGO:00512522240.053
signal transduction in absence of ligandGO:003803410.052
cellular nitrogen compound biosynthetic processGO:00442712180.052
agingGO:000756820.052
regulation of rna biosynthetic processGO:20011412130.052
negative regulation of cell deathGO:0060548600.052
Human Mouse
regulation of cell killingGO:003134120.052
intracellular signal transductionGO:0035556850.052
positive regulation of programmed cell deathGO:0043068290.051
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.051
Human Mouse
symbiosis encompassing mutualism through parasitismGO:004440340.051
secondary metabolic processGO:001974830.050
organic cyclic compound biosynthetic processGO:19013622230.050
determination of left right symmetryGO:00073681790.049
establishment of protein localization to organelleGO:007259440.049
regulation of gene expressionGO:00104682650.049
proteolysis involved in cellular protein catabolic processGO:005160330.049
embryo development ending in birth or egg hatchingGO:00097922710.049
mitotic dna damage checkpointGO:004477340.049
fertilizationGO:000956630.049
modification dependent protein catabolic processGO:001994130.049
regulation of localizationGO:00328791040.048
Human
cell part morphogenesisGO:00329902460.048
organic substance biosynthetic processGO:19015762890.048
cell substrate adhesionGO:003158940.047
regulation of cysteine type endopeptidase activityGO:2000116210.046
negative regulation of programmed cell deathGO:0043069580.046
Human Mouse
negative regulation of protein phosphorylationGO:000193340.046
generation of neuronsGO:00486993850.046
multi organism cellular processGO:004476420.046
localization of cellGO:00516742440.045
phosphorus metabolic processGO:00067931090.045
nuclear importGO:005117030.045
organelle fusionGO:004828430.045
single organism transportGO:00447652060.044
Human
response to abiotic stimulusGO:00096281220.044
cellular protein modification processGO:00064641000.044
nucleocytoplasmic transportGO:000691340.044
gland developmentGO:00487321430.044
membrane fusionGO:006102520.044
immune system developmentGO:00025201910.044
somitogenesisGO:0001756870.043
guanosine containing compound metabolic processGO:190106840.043
protein localization to nucleusGO:003450430.043
regulation of multicellular organismal developmentGO:20000262230.043
nucleobase containing compound biosynthetic processGO:00346542050.043
protein import into nucleusGO:000660630.043
cell projection organizationGO:00300302840.042
gtp catabolic processGO:000618420.042
protein polyubiquitinationGO:000020940.042
response to lipidGO:0033993600.042
regulation of hematopoietic progenitor cell differentiationGO:190153210.042
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.042
cellular component morphogenesisGO:00329893360.042
organonitrogen compound metabolic processGO:1901564740.042
axon developmentGO:00615641660.041
nucleic acid metabolic processGO:00903042440.041
positive regulation of response to stimulusGO:0048584800.040
Mouse
neuron projection morphogenesisGO:00488121610.040
immune responseGO:0006955280.040
regionalizationGO:00030022740.040
determination of bilateral symmetryGO:00098552040.040
phosphate containing compound metabolic processGO:00067961080.040
cytokinesisGO:000091030.039
homeostatic processGO:00425921420.039
positive regulation of stress activated mapk cascadeGO:003287430.039
regulation of extrinsic apoptotic signaling pathwayGO:200123630.039
Human Mouse
viral processGO:001603210.039
rna metabolic processGO:00160702190.038
negative regulation of biological processGO:00485193040.038
Human Mouse
positive regulation of metabolic processGO:00098931080.038
phosphorylationGO:0016310690.038
response to stressGO:00069502630.038
specification of symmetryGO:00097992040.038
cellular amine metabolic processGO:004410620.038
nucleic acid templated transcriptionGO:00976591810.037
regulation of primary metabolic processGO:00800903110.036
positive regulation of macromolecule metabolic processGO:0010604930.036
reactive oxygen species metabolic processGO:007259360.036
gtp metabolic processGO:004603940.036
axonogenesisGO:00074091520.036
neuron developmentGO:00486662620.036
positive regulation of cell cycleGO:004578730.035
regulation of biological qualityGO:00650082630.035
protein targeting to nucleusGO:004474430.035
response to amino acidGO:004320020.035
guanosine containing compound catabolic processGO:190106920.035
regulation of reactive oxygen species metabolic processGO:200037720.035
regulation of transcription from rna polymerase ii promoterGO:00063571140.035
cellular response to stressGO:0033554620.035
larval developmentGO:000216420.034
positive regulation of cell killingGO:003134320.034
leukocyte differentiationGO:0002521250.034
phagocytosisGO:000690930.034
cell motilityGO:00488702440.034
regulation of peptidase activityGO:0052547230.034
interspecies interaction between organismsGO:004441940.034
cellular amino acid metabolic processGO:000652070.034
actin filament based movementGO:003004810.033
protein modification processGO:00362111000.033
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.033
vasculature developmentGO:00019442780.033
developmental pigmentationGO:0048066480.033
positive regulation of cellular metabolic processGO:0031325940.033
macromolecule biosynthetic processGO:00090592270.033
regulation of jak stat cascadeGO:004642530.033
nik nf kappab signalingGO:003806110.033
regulation of intracellular signal transductionGO:1902531570.033
somite developmentGO:0061053960.033
neuron projection developmentGO:00311751800.032
response to alkaloidGO:004327920.032
interaction with hostGO:005170140.032
regulation of establishment of protein localizationGO:007020140.032
regulation of peptidyl tyrosine phosphorylationGO:005073010.032
single organism organelle organizationGO:19025891990.032
biosynthetic processGO:00090582940.032
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.031
Human Mouse
regulation of gtp catabolic processGO:003312420.031
cellular component movementGO:00069283350.031
aromatic compound biosynthetic processGO:00194382170.031
positive regulation of i kappab kinase nf kappab signalingGO:004312330.031
killing of cells in other organism involved in symbiotic interactionGO:005188310.031
system processGO:00030081850.031
single organism nuclear importGO:190259330.030
maintenance of locationGO:005123540.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.030
erk1 and erk2 cascadeGO:007037140.030
taxisGO:00423301090.030
transcription from rna polymerase ii promoterGO:0006366800.030
response to xenobiotic stimulusGO:0009410450.030
amine metabolic processGO:000930820.030
cellular ketone metabolic processGO:0042180110.030
regulation of protein catabolic processGO:004217610.030
regulation of production of molecular mediator of immune responseGO:000270010.030
regulation of cell developmentGO:00602841000.030
peptidyl serine phosphorylationGO:001810510.030
cellular response to organic substanceGO:00713101050.029
centrosome organizationGO:005129710.029
centrosome cycleGO:000709810.029
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.029
multicellular organism growthGO:003526440.029
positive regulation of catabolic processGO:000989640.029
regulation of protein transportGO:005122330.029
cellular component biogenesisGO:00440851780.029
adult behaviorGO:003053420.028
regulation of phosphorus metabolic processGO:0051174430.028
hormone transportGO:000991420.028
negative regulation of apoptotic processGO:0043066550.028
Human Mouse
cell morphogenesisGO:00009022890.028
membrane invaginationGO:001032410.028
positive regulation of secretionGO:005104710.028
enzyme linked receptor protein signaling pathwayGO:00071671060.028
carboxylic acid metabolic processGO:0019752220.028
regulation of multicellular organism growthGO:004001440.028
positive regulation of jnk cascadeGO:004633030.028
response to oxygen containing compoundGO:1901700550.028
regulation of cytoplasmic transportGO:190364940.027
negative chemotaxisGO:005091910.027
regulation of blood vessel sizeGO:005088020.027
innate immune responseGO:0045087130.027
single organism localizationGO:19025782250.027
Human
myeloid cell differentiationGO:0030099860.027
head developmentGO:00603223030.027
embryonic heart tube morphogenesisGO:00031431080.027
cellular response to endogenous stimulusGO:0071495680.027
meiotic nuclear divisionGO:000712640.027
regulation of protein import into nucleusGO:004230620.027
positive regulation of map kinase activityGO:004340630.026
zymogen activationGO:003163830.026
regulation of protein metabolic processGO:0051246560.026
cell migration involved in gastrulationGO:0042074790.026
regulation of cellular amino acid metabolic processGO:000652100.026
cellular response to decreased oxygen levelsGO:003629410.026
p38mapk cascadeGO:003806610.026
phagocytosis engulfmentGO:000691110.026
b cell activationGO:004211320.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
regulation of cellular protein catabolic processGO:190336210.026
anterior posterior pattern specificationGO:00099521520.025
locomotionGO:00400113130.025
positive regulation of signal transductionGO:0009967560.025
Mouse
regulation of cellular amine metabolic processGO:003323800.025
cellular response to growth factor stimulusGO:0071363390.025
positive regulation of secretion by cellGO:190353210.025
mitotic dna integrity checkpointGO:004477440.024
regulation of cell differentiationGO:00455951420.024
regulation of tube sizeGO:003515020.024
reactive nitrogen species metabolic processGO:200105700.024
antimicrobial humoral responseGO:001973020.024
hormone secretionGO:004687920.024
cellular response to dna damage stimulusGO:0006974240.024
regulation of protein localization to nucleusGO:190018020.024
motor neuron axon guidanceGO:0008045230.024
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.024
negative regulation of mitosisGO:004583930.024
production of molecular mediator of immune responseGO:000244020.024
stem cell maintenanceGO:001982740.024
positive regulation of cellular catabolic processGO:003133130.024
actin cytoskeleton organizationGO:0030036630.024
stem cell divisionGO:001714510.023
cortical actin cytoskeleton organizationGO:003086610.023
regulation of nucleotide catabolic processGO:003081120.023
regulation of cell projection assemblyGO:006049140.023
protein localization to plasma membraneGO:007265910.023
small molecule metabolic processGO:0044281770.023
embryonic organ morphogenesisGO:00485622740.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
Mouse
regulation of phosphorylationGO:0042325260.023
regulation of developmental processGO:00507932470.023
regulation of stem cell proliferationGO:007209120.022
cellular carbohydrate metabolic processGO:004426240.022
glucose homeostasisGO:004259310.022
regulation of protein targetingGO:190353320.022
regulation of heart growthGO:006042020.022
cell matrix adhesionGO:000716040.022
response to glucocorticoidGO:005138410.022
ear developmentGO:00435831270.022
pigment cell differentiationGO:0050931380.022
oxoacid metabolic processGO:0043436310.022
pigmentationGO:0043473850.021
cell proliferationGO:0008283800.021
central nervous system developmentGO:00074173870.021
response to bacteriumGO:0009617580.021
positive regulation of protein complex assemblyGO:003133420.021
cellular lipid metabolic processGO:0044255360.021
proteolysisGO:0006508380.021
regulation of system processGO:0044057400.021
response to hormoneGO:0009725480.021
protein importGO:001703830.021
positive regulation of cell adhesionGO:004578510.021
cellular response to radiationGO:007147840.021
defense response to other organismGO:0098542330.021
actomyosin structure organizationGO:0031032530.021
regulation of anatomical structure morphogenesisGO:00226031300.020
microtubule organizing center organizationGO:003102310.020
regulation of cellular protein metabolic processGO:0032268520.020
negative regulation of protein kinase activityGO:000646940.020
embryonic skeletal system morphogenesisGO:0048704930.020
regulation of hormone secretionGO:004688320.020
cellular response to hormone stimulusGO:0032870390.020
regulation of blood pressureGO:000821710.020
ovulation cycleGO:004269820.020
blood circulationGO:0008015870.020
neurological system processGO:0050877620.020
convergent extensionGO:00600261180.020
macromolecule modificationGO:00434121110.020
carbohydrate homeostasisGO:003350010.020
regulation of molecular functionGO:0065009700.020
positive regulation of signalingGO:0023056560.020
Mouse
peptidyl serine modificationGO:001820920.020
cognitionGO:005089010.020
macromolecule localizationGO:0033036540.020
regulation of response to stressGO:0080134360.020
regulation of cellular ketone metabolic processGO:001056570.020
embryonic skeletal system developmentGO:0048706970.020
regulation of i kappab kinase nf kappab signalingGO:004312240.019
positive regulation of apoptotic processGO:0043065290.019
response to drugGO:004249330.019
single fertilizationGO:000733830.019
regulation of protein complex assemblyGO:004325430.019
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.019
regulation of cell morphogenesis involved in differentiationGO:0010769380.019
regulation of response to cytokine stimulusGO:006075930.019
establishment of protein localization to plasma membraneGO:009000210.019
establishment of localizationGO:00512342440.019
Human
protein secretionGO:000930610.019
embryonic limb morphogenesisGO:003032620.019
cell death in response to oxidative stressGO:003647320.019
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.019
Mouse
cellular component disassemblyGO:002241110.019
regulation of intracellular protein transportGO:003315730.019
i kappab kinase nf kappab signalingGO:000724940.019
response to organic cyclic compoundGO:0014070510.019
inner ear developmentGO:00488391260.019
melanin metabolic processGO:000658220.019
g1 s transition of mitotic cell cycleGO:000008210.018
negative regulation of hormone secretionGO:004688820.018
cellular response to external stimulusGO:007149620.018
neurotransmitter transportGO:000683620.018
regulation of cellular component organizationGO:0051128860.018
regulation of organ growthGO:004662030.018
regulation of filopodium assemblyGO:005148920.018
response to endogenous stimulusGO:0009719830.018
negative regulation of epithelial cell proliferationGO:005068010.018
post embryonic organ developmentGO:004856940.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of gtpase activityGO:004308720.018
regulation of locomotionGO:0040012550.018
regulation of axonogenesisGO:0050770320.017
positive regulation of immune effector processGO:000269930.017
cell substrate junction assemblyGO:000704420.017
convergent extension involved in gastrulationGO:0060027710.017
regulation of reproductive processGO:200024140.017
positive regulation of small gtpase mediated signal transductionGO:005105710.017
positive regulation of epithelial cell migrationGO:001063420.017
positive regulation of cell activationGO:005086710.017
positive regulation of cell communicationGO:0010647560.017
Mouse
defense responseGO:0006952470.017
development of primary female sexual characteristicsGO:004654540.017
digestive system developmentGO:00551232890.017
striated muscle cell differentiationGO:00511461290.017
protein complex subunit organizationGO:0071822460.017
organic acid metabolic processGO:0006082310.017
hepaticobiliary system developmentGO:0061008980.017
circulatory system processGO:0003013870.017
female sex differentiationGO:004666040.017
positive regulation of molecular functionGO:0044093330.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
negative regulation of kinase activityGO:003367340.016
lipid metabolic processGO:0006629520.016
neuroblast proliferationGO:000740520.016
cellular response to hypoxiaGO:007145610.016
homeostasis of number of cellsGO:0048872620.016
cellular component assemblyGO:00226071700.016
positive regulation of cellular protein metabolic processGO:0032270220.016
regulation of epithelial cell proliferationGO:005067830.016
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of immune system processGO:0002682340.016
negative regulation of cell communicationGO:0010648960.016
Human Mouse
mononuclear cell proliferationGO:003294310.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
response to mechanical stimulusGO:0009612240.016
positive regulation of hydrolase activityGO:0051345130.015
regulation of receptor activityGO:001046920.015
mitochondrial transportGO:000683920.015
regulation of cellular component movementGO:0051270550.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
positive regulation of gtpase activityGO:004354710.015
multi organism processGO:00517041340.015
digestive tract morphogenesisGO:00485462310.015
cellular response to biotic stimulusGO:007121630.015
cytokine mediated signaling pathwayGO:001922170.015
dorsal ventral pattern formationGO:00099531250.015
negative regulation of neuron projection regenerationGO:007057140.015
notochord developmentGO:0030903540.015
compound eye developmentGO:004874920.015
apoptotic process involved in developmentGO:190274220.015
leukocyte homeostasisGO:000177620.015
negative regulation of response to dna damage stimulusGO:200102130.015
negative regulation of protein serine threonine kinase activityGO:007190120.015
synaptic vesicle localizationGO:009747910.015
negative regulation of signal transduction by p53 class mediatorGO:190179780.015
macromolecular complex subunit organizationGO:0043933740.015
lymphocyte proliferationGO:004665110.015
kidney developmentGO:0001822920.015
transportGO:00068102200.015
Human
chemotaxisGO:00069351040.014
epithelial cell morphogenesisGO:000338220.014
cell cycle g1 s phase transitionGO:004484310.014
response to corticosteroidGO:003196010.014
regulation of establishment of protein localization to plasma membraneGO:009000310.014
embryonic heart tube developmentGO:00350501330.014
protein localizationGO:0008104400.014
lamellipodium assemblyGO:003003210.014
protein homooligomerizationGO:005126030.014
cellular response to extracellular stimulusGO:003166820.014
keratinocyte differentiationGO:003021600.014
axon guidanceGO:0007411860.014
endocrine processGO:005088620.014
regulation of cell morphogenesisGO:0022604420.014
b cell differentiationGO:003018310.014
response to fluid shear stressGO:003440520.014
regulation of cell activationGO:005086510.014
skeletal system developmentGO:00015011810.014
positive regulation of leukocyte differentiationGO:190210710.014
regulation of cell substrate adhesionGO:001081010.013
regulation of proteolysisGO:0030162240.013
er nucleus signaling pathwayGO:000698420.013
regulation of glucose importGO:004632410.013
Human
regulation of metal ion transportGO:001095940.013
epithelial tube morphogenesisGO:00605621480.013
osteoclast developmentGO:003603510.013
regulation of protein bindingGO:004339330.013
osteoclast differentiationGO:003031610.013
cellular response to oxygen levelsGO:007145310.013
exocytosisGO:000688710.013
response to decreased oxygen levelsGO:0036293250.013
endocrine system developmentGO:0035270650.013
lipid homeostasisGO:005508830.013
cellular localizationGO:0051641970.013
regulation of cytokine mediated signaling pathwayGO:000195930.013
positive regulation of wound healingGO:009030310.013
positive regulation of endothelial cell migrationGO:001059520.013
steroid hormone secretionGO:003592910.013
appendage developmentGO:0048736800.013
negative regulation of signalingGO:0023057960.013
Human Mouse
regulation of protein localization to plasma membraneGO:190307610.013
lymphocyte homeostasisGO:000226010.013
leukocyte chemotaxisGO:0030595120.013
cellular response to lipidGO:0071396390.013
extracellular structure organizationGO:0043062270.013
response to nutrientGO:000758430.013
positive regulation of lipid metabolic processGO:004583410.013
response to uvGO:000941130.013
regulation of defense response to virus by hostGO:005069110.013
cell morphogenesis involved in differentiationGO:00009041950.013
positive regulation of inflammatory responseGO:005072910.013

casp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
immune system diseaseDOID:291400.022
nervous system diseaseDOID:86300.020
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
hematopoietic system diseaseDOID:7400.018
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014