Danio rerio

33 known processes

casp9

caspase 9, apoptosis-related cysteine protease

(Aliases: zgc:101776,im:7136887)

casp9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.095
signal transductionGO:00071654550.073
Human
protein metabolic processGO:00195381830.073
Human
embryonic organ developmentGO:00485683810.070
larval developmentGO:000216420.060
cell projection morphogenesisGO:00488582440.059
cellular ketone metabolic processGO:0042180110.056
extrinsic apoptotic signaling pathwayGO:009719130.053
mitochondrion organizationGO:000700540.052
cellular macromolecule metabolic processGO:00442603910.051
positive regulation of protein complex assemblyGO:003133420.050
central nervous system developmentGO:00074173870.050
positive regulation of biological processGO:00485182530.050
maintenance of locationGO:005123540.049
cellular protein metabolic processGO:00442671290.049
ubiquitin dependent protein catabolic processGO:000651130.047
regulation of cell communicationGO:00106462320.046
intracellular signal transductionGO:0035556850.046
Human
regulation of protein complex assemblyGO:004325430.046
response to topologically incorrect proteinGO:003596620.044
guanosine containing compound metabolic processGO:190106840.043
multicellular organism growthGO:003526440.043
negative regulation of cellular processGO:00485232830.042
organelle organizationGO:00069962270.041
proteolysis involved in cellular protein catabolic processGO:005160330.041
developmental programmed cell deathGO:001062340.041
cellular protein catabolic processGO:004425740.040
regulation of metabolic processGO:00192223590.040
cell projection organizationGO:00300302840.039
positive regulation of apoptotic signaling pathwayGO:200123510.039
response to chemicalGO:00422213200.039
establishment of protein localization to organelleGO:007259440.039
determination of left right symmetryGO:00073681790.038
determination of bilateral symmetryGO:00098552040.038
regulation of primary metabolic processGO:00800903110.038
cellular component movementGO:00069283350.038
specification of symmetryGO:00097992040.038
embryonic limb morphogenesisGO:003032620.037
positive regulation of cellular processGO:00485222010.037
positive regulation of cell cycleGO:004578730.037
positive regulation of cellular component biogenesisGO:004408930.036
apoptotic process involved in developmentGO:190274220.036
regulation of multicellular organismal processGO:00512392770.036
positive regulation of cell killingGO:003134320.035
cellular response to external stimulusGO:007149620.035
regulation of extrinsic apoptotic signaling pathwayGO:200123630.035
g1 s transition of mitotic cell cycleGO:000008210.035
cell cycle g1 s phase transitionGO:004484310.035
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.034
cell morphogenesisGO:00009022890.034
brain developmentGO:00074202930.034
tube morphogenesisGO:00352393490.034
regulation of signalingGO:00230512350.033
lipid catabolic processGO:001604240.032
heart morphogenesisGO:00030071560.032
regulation of signal transductionGO:00099662250.032
post embryonic organ developmentGO:004856940.032
transportGO:00068102200.031
positive regulation of catabolic processGO:000989640.031
cellular response to topologically incorrect proteinGO:003596720.031
synaptic vesicle localizationGO:009747910.031
negative regulation of protein kinase activityGO:000646940.030
embryonic organ morphogenesisGO:00485622740.030
autophagyGO:000691440.030
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.029
cell surface receptor signaling pathwayGO:00071663250.029
growthGO:00400071740.029
stem cell proliferationGO:007208940.029
regulation of organ growthGO:004662030.029
modification dependent macromolecule catabolic processGO:004363230.029
cellular response to chemical stimulusGO:00708871570.029
neuron projection morphogenesisGO:00488121610.029
positive regulation of cellular catabolic processGO:003133130.029
modification dependent protein catabolic processGO:001994130.028
regulation of biological qualityGO:00650082630.028
membrane fusionGO:006102520.028
axonogenesisGO:00074091520.028
regulation of jak stat cascadeGO:004642530.028
neuron developmentGO:00486662620.028
morphogenesis of an epitheliumGO:00020093330.028
cellular component morphogenesisGO:00329893360.028
regulation of macromolecule metabolic processGO:00602553170.028
negative regulation of protein phosphorylationGO:000193340.027
guanosine containing compound catabolic processGO:190106920.027
neuron differentiationGO:00301823530.027
axon developmentGO:00615641660.027
cellular response to nutrient levelsGO:003166920.027
lipid storageGO:001991510.027
positive regulation of transportGO:005105020.026
cilium morphogenesisGO:0060271850.026
regulation of multicellular organism growthGO:004001440.026
phagocytosisGO:000690930.026
signal transduction in absence of ligandGO:003803410.026
cellular response to starvationGO:000926710.025
cilium assemblyGO:0042384580.025
cell substrate adhesionGO:003158940.025
centrosome organizationGO:005129710.025
positive regulation of neuron apoptotic processGO:004352510.024
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.024
regulation of response to stimulusGO:00485832690.024
Human
cellular response to extracellular stimulusGO:003166820.024
response to stressGO:00069502630.024
Human
regulation of metal ion transportGO:001095940.024
regulation of nucleotide catabolic processGO:003081120.024
heart developmentGO:00075073130.024
system processGO:00030081850.024
negative regulation of biological processGO:00485193040.024
protein acylationGO:004354330.023
regulation of stem cell proliferationGO:007209120.023
cognitionGO:005089010.023
regulation of cytokine productionGO:000181730.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
gene expressionGO:00104672520.023
amine metabolic processGO:000930820.022
response to glucoseGO:000974930.022
cell part morphogenesisGO:00329902460.022
single organism organelle organizationGO:19025891990.022
apoptotic process involved in morphogenesisGO:006056120.022
mitochondrial transportGO:000683920.022
odontogenesis of dentin containing toothGO:004247510.022
regulation of apoptotic processGO:0042981980.022
er nucleus signaling pathwayGO:000698420.022
immune system processGO:00023762410.021
cilium organizationGO:0044782710.021
cellular amine metabolic processGO:004410620.021
meiotic cell cycle processGO:190304630.021
locomotor rhythmGO:004547530.021
heart loopingGO:0001947940.021
regulation of protein catabolic processGO:004217610.021
regulation of cell deathGO:00109411030.020
regulation of cell killingGO:003134120.020
regulation of nucleoside metabolic processGO:000911820.020
negative regulation of protein serine threonine kinase activityGO:007190120.020
microtubule organizing center organizationGO:003102310.020
developmental growthGO:00485891660.020
endosome organizationGO:000703220.020
protein homooligomerizationGO:005126030.020
gtp catabolic processGO:000618420.020
regulation of bindingGO:005109830.020
regulation of purine nucleotide catabolic processGO:003312120.020
regulation of dendrite morphogenesisGO:004881430.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
gtp metabolic processGO:004603940.020
internal protein amino acid acetylationGO:000647520.020
proteasomal protein catabolic processGO:001049820.020
cellular response to unfolded proteinGO:003462020.020
response to ketoneGO:190165410.019
regulation of multicellular organismal developmentGO:20000262230.019
cell killingGO:000190620.019
regulation of mitochondrion organizationGO:001082110.019
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.019
establishment of synaptic vesicle localizationGO:009748010.019
hormone transportGO:000991420.019
sequestering of metal ionGO:005123830.019
synaptic vesicle transportGO:004848910.019
response to unfolded proteinGO:000698620.019
response to hydrogen peroxideGO:004254230.019
positive regulation of apoptotic processGO:0043065290.019
mitotic dna damage checkpointGO:004477340.019
synaptic growth at neuromuscular junctionGO:005112420.019
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.018
regulation of synaptic vesicle transportGO:190280310.018
regulation of dendrite developmentGO:005077330.018
single organism localizationGO:19025782250.018
epithelial tube morphogenesisGO:00605621480.018
deathGO:00162651210.018
gland developmentGO:00487321430.018
macromolecule modificationGO:00434121110.018
regulation of cellular amino acid metabolic processGO:000652100.018
immune system developmentGO:00025201910.018
nik nf kappab signalingGO:003806110.018
regulation of cellular ketone metabolic processGO:001056570.018
regulation of programmed cell deathGO:00430671010.018
meiosis iGO:000712710.018
response to corticosteroidGO:003196010.018
negative regulation of cellular catabolic processGO:003133030.018
positive regulation of secretionGO:005104710.017
camera type eye developmentGO:00430102220.017
inositol lipid mediated signalingGO:004801720.017
protein acetylationGO:000647320.017
regulation of synapse organizationGO:005080730.017
negative regulation of kinase activityGO:003367340.017
rna biosynthetic processGO:00327741810.017
killing of cells in other organism involved in symbiotic interactionGO:005188310.017
protein secretionGO:000930610.017
cell matrix adhesionGO:000716040.017
multi organism cellular processGO:004476420.017
eye developmentGO:00016542770.017
regulation of gtpase activityGO:004308720.017
response to external stimulusGO:00096052640.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
oxoacid metabolic processGO:0043436310.017
taxisGO:00423301090.016
endoplasmic reticulum unfolded protein responseGO:003096820.016
protein modification processGO:00362111000.016
homeostatic processGO:00425921420.016
cell morphogenesis involved in differentiationGO:00009041950.016
phosphate containing compound metabolic processGO:00067961080.016
determination of heart left right asymmetryGO:00613711170.016
cell cycleGO:0007049930.016
locomotionGO:00400113130.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
post embryonic morphogenesisGO:000988640.016
positive regulation of immune effector processGO:000269930.016
regulation of protein metabolic processGO:0051246560.016
hormone secretionGO:004687920.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
adult behaviorGO:003053420.016
cellular component biogenesisGO:00440851780.016
regulation of autophagyGO:001050630.016
peptidyl lysine acetylationGO:001839420.016
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.016
positive regulation of gtp catabolic processGO:003312610.016
embryonic heart tube developmentGO:00350501330.016
cellular localizationGO:0051641970.016
nucleobase containing compound metabolic processGO:00061392740.016
response to antibioticGO:004667710.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
cellular component assemblyGO:00226071700.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
organelle fusionGO:004828430.015
positive regulation of muscle organ developmentGO:004863610.015
regulation of cell differentiationGO:00455951420.015
cell deathGO:00082191210.015
regulation of phGO:000688530.015
cellular amino acid metabolic processGO:000652070.015
regulation of neurogenesisGO:0050767870.015
regulation of gtp catabolic processGO:003312420.015
spermatid differentiationGO:004851520.015
regulation of circadian rhythmGO:004275240.015
apoptotic processGO:00069151160.015
cell migrationGO:00164772370.015
tissue remodelingGO:004877140.015
viral processGO:001603210.015
interaction with hostGO:005170140.015
positive regulation of cell communicationGO:0010647560.015
peptidyl serine modificationGO:001820920.015
single organism membrane fusionGO:004480120.015
regulation of synaptic plasticityGO:004816710.015
response to glucocorticoidGO:005138410.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
nucleocytoplasmic transportGO:000691340.015
regulation of reproductive processGO:200024140.015
cellular component assembly involved in morphogenesisGO:00109271070.014
single organism nuclear importGO:190259330.014
secondary metabolic processGO:001974830.014
spermatid developmentGO:000728620.014
peptide transportGO:001583310.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
meiotic nuclear divisionGO:000712640.014
cellular biosynthetic processGO:00442492860.014
positive regulation of gtpase activityGO:004354710.014
regulation of hormone secretionGO:004688320.014
positive regulation of neuron deathGO:190121610.014
single organism transportGO:00447652060.014
regulation of sequestering of calcium ionGO:005128240.014
embryo development ending in birth or egg hatchingGO:00097922710.014
protein polyubiquitinationGO:000020940.014
regulation of skeletal muscle tissue developmentGO:004864140.014
leukocyte homeostasisGO:000177620.014
zymogen activationGO:003163830.014
mitotic dna integrity checkpointGO:004477440.014
positive regulation of cytokine productionGO:000181920.014
organic cyclic compound biosynthetic processGO:19013622230.014
sensory perception of chemical stimulusGO:000760630.014
regulation of establishment of protein localizationGO:007020140.014
response to nutrientGO:000758430.014
regulation of epithelial cell proliferationGO:005067830.014
localization of cellGO:00516742440.014
regulation of inflammatory responseGO:005072720.014
protein localization to nucleusGO:003450430.014
response to organic substanceGO:00100331530.014
regulation of cellular metabolic processGO:00313233200.014
head developmentGO:00603223030.014
response to alkaloidGO:004327920.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regionalizationGO:00030022740.014
interspecies interaction between organismsGO:004441940.014
nuclear importGO:005117030.014
convergent extensionGO:00600261180.013
regulation of protein bindingGO:004339330.013
modulation by virus of host morphology or physiologyGO:001904810.013
regulation of transcription dna templatedGO:00063552130.013
mitochondrion morphogenesisGO:007058420.013
b cell activationGO:004211320.013
gastrulationGO:00073692080.013
generation of neuronsGO:00486993850.013
retina development in camera type eyeGO:00600411460.013
type b pancreatic cell developmentGO:000332340.013
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.013
cell motilityGO:00488702440.013
i kappab kinase nf kappab signalingGO:000724940.013
regulation of meiotic cell cycleGO:005144510.013
renal system developmentGO:0072001940.013
neuron projection developmentGO:00311751800.013
regulation of cellular amine metabolic processGO:003323800.013
programmed cell deathGO:00125011190.013
protein targeting to nucleusGO:004474430.013
sensory organ developmentGO:00074233930.013
cell agingGO:000756920.013
production of molecular mediator of immune responseGO:000244020.013
embryonic heart tube morphogenesisGO:00031431080.013
regulation of response to oxidative stressGO:190288220.013
sleepGO:003043110.013
positive regulation of stress activated mapk cascadeGO:003287430.013
regulation of nitrogen compound metabolic processGO:00511712510.013
response to vitaminGO:003327330.013
positive regulation of nucleoside metabolic processGO:004597910.013
phosphorylationGO:0016310690.013
synaptic vesicle recyclingGO:003646510.013
cellular response to molecule of bacterial originGO:007121930.012
regulation of cellular component organizationGO:0051128860.012
toxin metabolic processGO:000940410.012
positive regulation of map kinase activityGO:004340630.012
positive regulation of nucleotide catabolic processGO:003081310.012
lateral inhibitionGO:004633110.012
cell death in response to oxidative stressGO:003647320.012
regulation of stem cell differentiationGO:200073640.012
cellular response to stressGO:0033554620.012
Human
neuron remodelingGO:001632210.012
reactive oxygen species biosynthetic processGO:190340910.012
regulation of intracellular phGO:005145310.012
fertilizationGO:000956630.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
epithelial cell differentiationGO:00308551160.012
calcium ion importGO:007050940.012
regulation of calcium ion transportGO:005192420.012
positive regulation of striated muscle tissue developmentGO:004584410.012
protein polymerizationGO:005125840.012
organelle assemblyGO:00709251100.012
centrosome cycleGO:000709810.012
negative regulation of tor signalingGO:003200720.012
regulation of blood pressureGO:000821710.012
negative regulation of sequestering of calcium ionGO:005128340.012
sequestering of calcium ionGO:005120830.012
nitrogen compound metabolic processGO:00068073190.012
cellular response to biotic stimulusGO:007121630.012
cytokinesisGO:000091030.012
translational initiationGO:000641330.012
regulation of synapse assemblyGO:005196330.012
vasculature developmentGO:00019442780.012
positive regulation of muscle tissue developmentGO:190186310.012
protein importGO:001703830.012
establishment of localizationGO:00512342440.012
cellular component disassemblyGO:002241110.012
small molecule metabolic processGO:0044281770.012
endocrine processGO:005088620.012
hormone biosynthetic processGO:004244630.012
somite developmentGO:0061053960.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of protein transportGO:005122330.012
female sex differentiationGO:004666040.012
negative regulation of catabolic processGO:000989530.011
organic acid metabolic processGO:0006082310.011
regulation of cell activationGO:005086510.011
atp catabolic processGO:000620040.011
nuclear transportGO:005116940.011
regulation of intracellular signal transductionGO:1902531570.011
regulation of response to cytokine stimulusGO:006075930.011
positive regulation of cell activationGO:005086710.011
regulation of organelle assemblyGO:190211540.011
macroautophagyGO:001623610.011
compound eye developmentGO:004874920.011
proteolysisGO:0006508380.011
Human
regulation of molecular functionGO:0065009700.011
development of primary female sexual characteristicsGO:004654540.011
cytokinetic processGO:003250620.011
regulation of cytoplasmic transportGO:190364940.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
alcohol biosynthetic processGO:004616520.011
negative regulation of cell communicationGO:0010648960.011
positive regulation of metabolic processGO:00098931080.011
regulation of receptor mediated endocytosisGO:004825940.011
cytoskeleton dependent cytokinesisGO:006164030.011
pancreas developmentGO:0031016840.011
negative regulation of mapk cascadeGO:004340940.011
sensory organ morphogenesisGO:00905962000.011
fatty acid oxidationGO:001939510.011
sensory perception of smellGO:000760820.011
mesenchyme developmentGO:00604851270.011
cytoplasm organizationGO:000702840.011
establishment of protein localization to plasma membraneGO:009000210.011
neuron projection guidanceGO:0097485860.011
positive regulation of cell deathGO:0010942290.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
regulation of protein localization to nucleusGO:190018020.011
lymphocyte proliferationGO:004665110.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
establishment of localization in cellGO:0051649770.011
regulation of protein ubiquitinationGO:003139630.011
regulation of anatomical structure morphogenesisGO:00226031300.011
membrane invaginationGO:001032410.011
negative regulation of cytoplasmic transportGO:190365020.011
entrainment of circadian clockGO:000964920.011
sex determinationGO:000753010.011
protein import into nucleusGO:000660630.011
golgi vesicle transportGO:004819330.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
regulation of neuron differentiationGO:0045664560.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of cellular biosynthetic processGO:00313262450.011
regulation of production of molecular mediator of immune responseGO:000270010.011
eye morphogenesisGO:00485921440.011
phosphatidylinositol mediated signalingGO:004801520.011
actin filament based movementGO:003004810.011
macromolecular complex disassemblyGO:003298410.011
hemopoiesisGO:00300971830.011
cellular protein modification processGO:00064641000.010
cellular carbohydrate metabolic processGO:004426240.010
positive regulation of secretion by cellGO:190353210.010
response to other organismGO:0051707970.010
cellular response to reactive oxygen speciesGO:003461420.010
stem cell maintenanceGO:001982740.010
single organism metabolic processGO:00447102170.010
circadian sleep wake cycle processGO:002241020.010
meiotic chromosome segregationGO:004513230.010
cellular monovalent inorganic cation homeostasisGO:003000420.010
neurotransmitter transportGO:000683620.010
neuroblast proliferationGO:000740520.010
regulation of cellular protein catabolic processGO:190336210.010
regulation of protein import into nucleusGO:004230620.010
neurotransmitter secretionGO:000726920.010
cytosolic calcium ion transportGO:006040130.010
regulation of catalytic activityGO:0050790550.010
alpha amino acid metabolic processGO:190160530.010
regulation of rna metabolic processGO:00512522240.010
female gonad developmentGO:000858540.010
regulation of cell shapeGO:000836010.010
calcium ion transport into cytosolGO:006040230.010
behaviorGO:0007610740.010
regulation of nervous system developmentGO:0051960900.010
positive regulation of lipid metabolic processGO:004583410.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
regulation of canonical wnt signaling pathwayGO:0060828340.010
digestive system developmentGO:00551232890.010
response to hexoseGO:000974630.010
modification of morphology or physiology of other organismGO:003582140.010
negative regulation of apoptotic processGO:0043066550.010

casp9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.076
disease of metabolismDOID:001466700.028
musculoskeletal system diseaseDOID:1700.023
lysosomal storage diseaseDOID:321100.023
inherited metabolic disorderDOID:65500.023
organ system cancerDOID:005068600.021
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
cardiovascular system diseaseDOID:128700.021
nervous system diseaseDOID:86300.017
lipid storage diseaseDOID:945500.011