Danio rerio

131 known processes

hdac1

histone deacetylase 1

(Aliases: zgc:101582,wu:fb19h11,wu:fi06f03,mp:zf637-2-001987,zgc:65818,chunp6919,hdac-1,MGC101582)

hdac1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.971
embryonic organ developmentGO:00485683810.900
Worm
larval developmentGO:000216420.862
Worm
camera type eye developmentGO:00430102220.796
sensory organ developmentGO:00074233930.738
embryonic organ morphogenesisGO:00485622740.735
Worm
nucleic acid metabolic processGO:00903042440.672
Human Mouse Worm Fly
regulation of developmental processGO:00507932470.624
eye developmentGO:00016542770.624
cellular component morphogenesisGO:00329893360.558
Fly
vasculature developmentGO:00019442780.520
organic cyclic compound metabolic processGO:19013603010.510
Human Mouse Worm Fly
epithelial cell differentiationGO:00308551160.490
retina development in camera type eyeGO:00600411460.490
gene expressionGO:00104672520.456
Human Mouse Worm Fly
organelle organizationGO:00069962270.441
Human Mouse Worm Fly
regulation of multicellular organism growthGO:004001440.428
chromatin modificationGO:0016568210.421
Human Mouse Worm Fly
growthGO:00400071740.408
heterocycle metabolic processGO:00464832900.370
Human Mouse Worm Fly
neural retina developmentGO:0003407490.368
negative regulation of cellular processGO:00485232830.360
cell morphogenesisGO:00009022890.338
Fly
generation of neuronsGO:00486993850.338
chordate embryonic developmentGO:00430092710.321
glial cell differentiationGO:0010001420.318
blood vessel morphogenesisGO:00485142160.311
mitotic g2 dna damage checkpointGO:000709530.294
cell projection organizationGO:00300302840.294
Fly
regulation of growthGO:0040008420.294
positive regulation of rna metabolic processGO:0051254590.284
Human Worm
rna biosynthetic processGO:00327741810.279
Human Mouse Worm Fly
cellular biosynthetic processGO:00442492860.274
Human Mouse Worm Fly
cellular nitrogen compound metabolic processGO:00346412900.272
Human Mouse Worm Fly
cellular component assemblyGO:00226071700.271
central nervous system neuron differentiationGO:0021953740.266
rna metabolic processGO:00160702190.266
Human Mouse Worm Fly
determination of bilateral symmetryGO:00098552040.265
biosynthetic processGO:00090582940.263
Human Mouse Worm Fly
regulation of apoptotic processGO:0042981980.247
Mouse
regulation of macromolecule metabolic processGO:00602553170.246
Human Mouse Worm Fly
morphogenesis of an epitheliumGO:00020093330.243
nucleobase containing compound metabolic processGO:00061392740.238
Human Mouse Worm Fly
striated muscle tissue developmentGO:00147061100.237
developmental growthGO:00485891660.234
hematopoietic or lymphoid organ developmentGO:00485341910.221
regulation of gene expressionGO:00104682650.214
Human Mouse Worm Fly
nitrogen compound metabolic processGO:00068073190.213
Human Mouse Worm Fly
determination of heart left right asymmetryGO:00613711170.209
regionalizationGO:00030022740.204
camera type eye morphogenesisGO:00485931080.200
cellular nitrogen compound biosynthetic processGO:00442712180.200
Human Mouse Worm Fly
dorsal ventral pattern formationGO:00099531250.196
epithelial tube morphogenesisGO:00605621480.188
regulation of multicellular organismal developmentGO:20000262230.182
organic cyclic compound biosynthetic processGO:19013622230.176
Human Mouse Worm Fly
inner ear developmentGO:00488391260.174
regulation of cell differentiationGO:00455951420.170
tissue regenerationGO:0042246740.167
positive regulation of biological processGO:00485182530.167
cellular component biogenesisGO:00440851780.164
regenerationGO:0031099910.161
nucleic acid templated transcriptionGO:00976591810.152
Human Mouse Worm Fly
heart morphogenesisGO:00030071560.152
head developmentGO:00603223030.151
single organism organelle organizationGO:19025891990.149
Human Mouse Worm Fly
regulation of mrna processingGO:005068430.148
meiotic nuclear divisionGO:000712640.146
regulation of rna metabolic processGO:00512522240.145
Human Mouse Worm Fly
regulation of cellular biosynthetic processGO:00313262450.145
Human Mouse Worm Fly
cell part morphogenesisGO:00329902460.142
Fly
regulation of primary metabolic processGO:00800903110.140
Human Mouse Worm Fly
protein acetylationGO:000647320.139
regulation of cell deathGO:00109411030.136
Mouse
heart developmentGO:00075073130.133
positive regulation of metabolic processGO:00098931080.133
Human Worm
nuclear transportGO:005116940.131
tube morphogenesisGO:00352393490.130
Worm
embryo development ending in birth or egg hatchingGO:00097922710.130
cell projection morphogenesisGO:00488582440.126
Fly
cell motilityGO:00488702440.122
regulation of nitrogen compound metabolic processGO:00511712510.121
Human Mouse Worm Fly
stem cell differentiationGO:00488631170.118
cellular aromatic compound metabolic processGO:00067252950.116
Human Mouse Worm Fly
neuron developmentGO:00486662620.108
Fly
positive regulation of histone modificationGO:003105810.102
digestive system developmentGO:00551232890.102
locomotionGO:00400113130.102
eye morphogenesisGO:00485921440.100
cellular protein catabolic processGO:004425740.100
organic substance biosynthetic processGO:19015762890.099
Human Mouse Worm Fly
positive regulation of chromatin modificationGO:190331010.099
regulation of biological qualityGO:00650082630.098
Human
pigmentationGO:0043473850.098
cell migration involved in heart developmentGO:0060973220.098
transcription from rna polymerase ii promoterGO:0006366800.096
Human Mouse Worm Fly
establishment of protein localization to organelleGO:007259440.095
specification of symmetryGO:00097992040.095
muscle structure developmentGO:00610611960.095
Fly
cellular macromolecule biosynthetic processGO:00346452240.094
Human Mouse Worm Fly
brain developmentGO:00074202930.093
liver developmentGO:0001889960.093
regulation of nucleobase containing compound metabolic processGO:00192192500.092
Human Mouse Worm Fly
angiogenesisGO:00015251580.091
regulation of response to stimulusGO:00485832690.090
Human Mouse Worm Fly
rna transportGO:005065820.090
histone modificationGO:0016570200.088
Human Mouse Worm Fly
negative regulation of rna metabolic processGO:0051253480.086
Human Mouse Worm Fly
single organism localizationGO:19025782250.085
cell cycleGO:0007049930.082
apoptotic processGO:00069151160.082
Mouse Worm
chromatin organizationGO:0006325220.082
Human Mouse Worm Fly
developmental pigmentationGO:0048066480.081
negative regulation of cellular biosynthetic processGO:0031327550.079
Human Mouse Worm Fly
chromosome organizationGO:0051276310.079
Human Mouse Worm Fly
deathGO:00162651210.077
Mouse Worm
single organism metabolic processGO:00447102170.077
Human Mouse Worm Fly
axon developmentGO:00615641660.077
Fly
macromolecule modificationGO:00434121110.076
Human Mouse Worm Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.075
Human Mouse Worm Fly
positive regulation of rna biosynthetic processGO:1902680570.075
Human Worm
cellular macromolecule metabolic processGO:00442603910.075
Human Mouse Worm Fly
proteolysis involved in cellular protein catabolic processGO:005160330.074
aromatic compound biosynthetic processGO:00194382170.074
Human Mouse Worm Fly
positive regulation of cell cycleGO:004578730.073
neuron differentiationGO:00301823530.073
Mouse Fly
agingGO:000756820.073
Fly
regulation of cellular component organizationGO:0051128860.071
Fly
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.071
multicellular organism growthGO:003526440.070
protein localization to nucleusGO:003450430.069
dna metabolic processGO:0006259270.068
Worm
hepaticobiliary system developmentGO:0061008980.068
ribosomal small subunit biogenesisGO:004227420.067
regulation of glial cell differentiationGO:004568540.066
Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.065
Human Mouse Worm Fly
regulation of meiotic cell cycleGO:005144510.064
rna localizationGO:000640340.064
protein import into nucleusGO:000660630.062
blood vessel developmentGO:00015682460.062
segmentationGO:0035282970.062
Fly
regulation of cell shapeGO:000836010.061
positive regulation of dna metabolic processGO:005105410.061
organelle assemblyGO:00709251100.061
programmed cell deathGO:00125011190.061
Mouse Worm
gland developmentGO:00487321430.060
peptidyl lysine acetylationGO:001839420.060
negative regulation of biological processGO:00485193040.059
cellular macromolecular complex assemblyGO:0034622240.059
regulation of rna biosynthetic processGO:20011412130.059
Human Mouse Worm Fly
ear developmentGO:00435831270.058
organic substance transportGO:0071702580.057
nucleocytoplasmic transportGO:000691340.055
establishment of localizationGO:00512342440.055
Worm
developmental growth involved in morphogenesisGO:0060560860.054
nucleobase containing compound biosynthetic processGO:00346542050.054
Human Mouse Worm Fly
anatomical structure homeostasisGO:0060249360.053
embryonic pattern specificationGO:0009880440.053
Fly
positive regulation of macromolecule biosynthetic processGO:0010557590.053
Human Worm
astrocyte differentiationGO:004870810.052
regulation of nervous system developmentGO:0051960900.052
retina morphogenesis in camera type eyeGO:0060042790.052
positive regulation of nitrogen compound metabolic processGO:0051173690.051
Human Worm
positive regulation of notch signaling pathwayGO:004574730.050
nucleic acid transportGO:005065720.049
pigment cell differentiationGO:0050931380.049
autophagyGO:000691440.049
mitotic dna damage checkpointGO:004477340.049
positive regulation of nucleic acid templated transcriptionGO:1903508570.048
Human Worm
regulation of signalingGO:00230512350.048
Human Mouse Worm
cellular protein metabolic processGO:00442671290.048
Human Mouse Worm Fly
double strand break repairGO:000630230.048
negative regulation of chromosome organizationGO:200125110.047
hemopoiesisGO:00300971830.047
regulation of nucleic acid templated transcriptionGO:19035062130.046
Human Mouse Worm Fly
positive regulation of nucleobase containing compound metabolic processGO:0045935690.046
Human Worm
cell migrationGO:00164772370.045
positive regulation of biosynthetic processGO:0009891680.045
Human Worm
muscle tissue developmentGO:00605371100.044
embryonic heart tube developmentGO:00350501330.044
protein desumoylationGO:001692610.043
positive regulation of cellular component biogenesisGO:004408930.043
wound healingGO:0042060900.043
negative regulation of cell differentiationGO:0045596460.042
Fly
nuclear importGO:005117030.041
xanthophore differentiationGO:005093630.041
protein importGO:001703830.041
cell morphogenesis involved in differentiationGO:00009041950.041
Fly
positive regulation of developmental processGO:0051094500.040
notochord developmentGO:0030903540.040
rna export from nucleusGO:000640510.040
regulation of growth rateGO:004000910.040
sensory organ morphogenesisGO:00905962000.040
negative regulation of biosynthetic processGO:0009890550.039
Human Mouse Worm Fly
positive regulation of transportGO:005105020.038
negative regulation of gene expressionGO:0010629650.038
Human Mouse Worm Fly
protein methylationGO:0006479130.038
anterior posterior pattern specificationGO:00099521520.037
neuron projection morphogenesisGO:00488121610.037
Fly
mitotic cell cycleGO:0000278640.037
maintenance of locationGO:005123540.036
skin developmentGO:0043588540.036
Mouse
biological adhesionGO:0022610400.036
positive regulation of chromosome organizationGO:200125210.035
protein acylationGO:004354330.035
cell deathGO:00082191210.034
Mouse Worm
oligodendrocyte differentiationGO:0048709230.034
regulation of transcription from rna polymerase ii promoterGO:00063571140.034
Human Mouse Worm Fly
mitotic g2 m transition checkpointGO:004481830.034
cellular protein modification processGO:00064641000.033
Human Mouse Worm Fly
determination of left right symmetryGO:00073681790.033
organic substance catabolic processGO:1901575280.032
meiotic cell cycle processGO:190304630.032
midbrain developmentGO:0030901280.031
embryonic heart tube morphogenesisGO:00031431080.031
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.031
Human Worm
heart loopingGO:0001947940.031
anterior posterior axis specificationGO:0009948200.031
covalent chromatin modificationGO:0016569200.031
Human Mouse Worm Fly
epithelial cell developmentGO:0002064420.030
cell divisionGO:0051301200.029
single organism reproductive processGO:0044702400.029
Worm
regulation of anatomical structure morphogenesisGO:00226031300.029
Fly
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.028
cell differentiation in spinal cordGO:0021515400.028
positive regulation of cellular processGO:00485222010.028
skeletal system developmentGO:00015011810.028
behaviorGO:0007610740.027
negative regulation of nucleic acid templated transcriptionGO:1903507450.027
Human Mouse Worm Fly
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.027
Human
regulation of mrna splicing via spliceosomeGO:004802430.026
positive regulation of cell deathGO:0010942290.026
positive regulation of transcription dna templatedGO:0045893570.026
Human Worm
embryonic digestive tract morphogenesisGO:004855730.026
Worm
mrna transportGO:005102820.026
negative regulation of nitrogen compound metabolic processGO:0051172590.026
Human Mouse Worm Fly
regulation of biosynthetic processGO:00098892500.026
Human Mouse Worm Fly
immune system processGO:00023762410.026
negative regulation of cell deathGO:0060548600.026
Mouse
homeostatic processGO:00425921420.025
protein targeting to nucleusGO:004474430.025
regulation of signal transductionGO:00099662250.025
Human Mouse Worm
histone deacetylationGO:001657520.025
Human Mouse Worm Fly
appendage developmentGO:0048736800.025
Mouse
retina layer formationGO:0010842240.025
nucleobase containing compound transportGO:001593120.024
establishment of rna localizationGO:005123630.024
ras protein signal transductionGO:000726570.024
Worm
regulation of nucleocytoplasmic transportGO:004682220.024
regulation of protein bindingGO:004339330.024
positive regulation of macromolecule metabolic processGO:0010604930.024
Human Worm
regulation of gene expression epigeneticGO:0040029110.023
Worm Fly
mitotic dna integrity checkpointGO:004477440.023
maturation of ssu rrnaGO:003049010.023
cell proliferationGO:0008283800.023
signal transductionGO:00071654550.023
ventral spinal cord interneuron specificationGO:002152130.022
internal peptidyl lysine acetylationGO:001839320.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
non recombinational repairGO:000072620.022
protein modification processGO:00362111000.022
Human Mouse Worm Fly
neurological system processGO:0050877620.022
nuclear exportGO:005116810.022
tongue morphogenesisGO:004358730.022
Mouse
protein metabolic processGO:00195381830.022
Human Mouse Worm Fly
negative regulation of developmental processGO:0051093650.021
Worm Fly
system processGO:00030081850.021
renal system developmentGO:0072001940.021
regulation of cell communicationGO:00106462320.021
Human Mouse Worm
mesenchyme developmentGO:00604851270.021
regulation of cellular metabolic processGO:00313233200.021
Human Mouse Worm Fly
mrna stabilizationGO:004825540.020
establishment or maintenance of cell polarityGO:0007163290.020
stem cell developmentGO:0048864820.020
taste bud formationGO:006119530.020
stem cell maintenanceGO:001982740.020
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.019
circulatory system processGO:0003013870.019
methylationGO:0032259220.019
activation of mapkkk activityGO:000018510.019
regulation of cell developmentGO:00602841000.019
transcription elongation from rna polymerase ii promoterGO:000636830.019
positive regulation of response to stimulusGO:0048584800.019
single organism cellular localizationGO:1902580460.019
meiotic chromosome segregationGO:004513230.019
regulation of cytoplasmic transportGO:190364940.019
rna stabilizationGO:004348940.019
reproductionGO:0000003400.019
Worm
cell cycle processGO:0022402530.019
regulation of neuron differentiationGO:0045664560.018
Fly
response to stressGO:00069502630.018
internal protein amino acid acetylationGO:000647520.018
stem cell proliferationGO:007208940.018
regulation of transcription dna templatedGO:00063552130.018
Human Mouse Worm Fly
positive regulation of cellular metabolic processGO:0031325940.018
Human Worm
regulation of embryonic developmentGO:0045995470.018
retinal pigment epithelium developmentGO:000340680.018
immune system developmentGO:00025201910.018
fin regenerationGO:0031101510.018
transcription dna templatedGO:00063511810.018
Human Mouse Worm Fly
mitotic cell cycle processGO:1903047480.018
sympathetic nervous system developmentGO:004848530.018
muscle organ developmentGO:00075171010.017
Fly
embryonic digestive tract developmentGO:004856640.017
Worm
skeletal muscle tissue developmentGO:0007519670.017
cell surface receptor signaling pathwayGO:00071663250.017
embryonic eye morphogenesisGO:0048048300.017
gliogenesisGO:0042063450.017
single organism nuclear importGO:190259330.017
regulation of histone methylationGO:003106030.017
regulation of establishment of protein localizationGO:007020140.017
cellular component disassemblyGO:002241110.017
regulation of multicellular organismal processGO:00512392770.017
cellular macromolecule localizationGO:0070727210.017
regulation of localizationGO:00328791040.017
negative regulation of apoptotic processGO:0043066550.017
Mouse
spliceosomal complex assemblyGO:000024510.017
pore complex assemblyGO:004693120.017
regulation of stem cell proliferationGO:007209120.016
negative regulation of macromolecule metabolic processGO:0010605760.016
Human Mouse Worm Fly
neural tube patterningGO:0021532330.016
female gamete generationGO:0007292140.016
macromolecule biosynthetic processGO:00090592270.016
Human Mouse Worm Fly
embryonic axis specificationGO:0000578120.016
positive regulation of signalingGO:0023056560.016
tissue remodelingGO:004877140.016
connective tissue developmentGO:0061448990.016
cell adhesionGO:0007155400.016
regulation of bindingGO:005109830.015
interspecies interaction between organismsGO:004441940.015
Human
negative regulation of epithelial cell differentiationGO:003085720.015
somitogenesisGO:0001756870.015
neuroblast proliferationGO:000740520.015
positive regulation of multicellular organismal processGO:0051240520.015
regulation of cell proliferationGO:0042127370.015
regulation of cell cycleGO:0051726520.014
positive regulation of gene expressionGO:0010628710.014
Human Worm
macromolecule methylationGO:0043414190.014
post embryonic developmentGO:000979170.014
Worm
regulation of protein transportGO:005122330.014
convergent extensionGO:00600261180.014
cell substrate junction assemblyGO:000704420.014
single organism transportGO:00447652060.014
regulation of organelle organizationGO:0033043290.014
response to light stimulusGO:0009416460.014
negative regulation of small gtpase mediated signal transductionGO:005105810.014
Worm
regulation of developmental growthGO:0048638380.014
peripheral nervous system developmentGO:0007422550.014
positive regulation of cellular protein metabolic processGO:0032270220.014
regulation of intracellular protein transportGO:003315730.014
negative regulation of ras protein signal transductionGO:004658010.014
Worm
response to woundingGO:00096111160.013
regulation of cellular protein metabolic processGO:0032268520.013
positive regulation of neural precursor cell proliferationGO:200017910.013
regulation of tube sizeGO:003515020.013
establishment of monopolar cell polarityGO:006116220.013
regulation of programmed cell deathGO:00430671010.013
Mouse
phosphate containing compound metabolic processGO:00067961080.013
endodermal cell fate determinationGO:000749320.013
intracellular transportGO:0046907320.013
axonogenesisGO:00074091520.013
Fly
cellular protein localizationGO:0034613200.013
heterocycle biosynthetic processGO:00181302150.013
Human Mouse Worm Fly
cell cell signalingGO:0007267520.013
notch signaling pathwayGO:0007219350.013
Worm
regulation of chromatin modificationGO:190330850.013
3 utr mediated mrna stabilizationGO:007093530.013
nephron epithelium morphogenesisGO:007208810.013
endodermal digestive tract morphogenesisGO:006103120.012
negative regulation of cell developmentGO:0010721260.012
Fly
macromolecule localizationGO:0033036540.012
hindbrain developmentGO:0030902910.012
nuclear pore complex assemblyGO:005129220.012
cellular localizationGO:0051641970.012
medulla oblongata developmentGO:002155040.012
negative regulation of meiotic cell cycleGO:005144710.012
multi organism cellular processGO:004476420.012
Human
cell morphogenesis involved in neuron differentiationGO:00486671630.012
Fly
protein polyubiquitinationGO:000020940.012
epithelial cell morphogenesisGO:000338220.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
Human
regulation of metabolic processGO:00192223590.011
Human Mouse Worm Fly
positive regulation of cell developmentGO:0010720250.011
intracellular signal transductionGO:0035556850.011
Mouse Worm
macromolecular complex subunit organizationGO:0043933740.011
Human Mouse Worm Fly
digestive tract developmentGO:00485652650.011
regulation of macromolecule biosynthetic processGO:00105562250.011
Human Mouse Worm Fly
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of phosphate metabolic processGO:0019220430.011
telomere organizationGO:003220010.011
response to organic substanceGO:00100331530.011
compound eye developmentGO:004874920.011
epidermis developmentGO:0008544480.011
Mouse
central nervous system neuron developmentGO:0021954290.011
cartilage developmentGO:0051216960.011
positive regulation of cellular amine metabolic processGO:003324000.011
photoreceptor cell differentiationGO:0046530550.011
positive regulation of proteolysisGO:0045862100.010
cilium morphogenesisGO:0060271850.010
positive regulation of embryonic developmentGO:004001930.010
taxisGO:00423301090.010
Fly
regulation of notch signaling pathwayGO:0008593160.010
Worm
enzyme linked receptor protein signaling pathwayGO:00071671060.010

hdac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.080
nervous system diseaseDOID:86300.024
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
musculoskeletal system cancerDOID:006010000.014
physical disorderDOID:008001500.013
developmental disorder of mental healthDOID:006003700.011
disease of mental healthDOID:15000.011
benign neoplasmDOID:006007200.011