Danio rerio

47 known processes

caspa

caspase a

(Aliases: zgc:109869,wu:fa93b02,fa93b02,caspy)

caspa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of defense response to virus by hostGO:000223000.875
regulation of defense response to virus by hostGO:005069110.807
zymogen activationGO:003163830.393
i kappab kinase nf kappab signalingGO:000724940.375
response to virusGO:0009615210.352
response to chemicalGO:00422213200.274
positive regulation of i kappab kinase nf kappab signalingGO:004312330.269
regulation of i kappab kinase nf kappab signalingGO:004312240.261
positive regulation of protein polymerizationGO:003227320.231
regulation of cytokine productionGO:000181730.221
cellular amide metabolic processGO:004360340.221
peptide metabolic processGO:000651810.219
sleepGO:003043110.218
protein polymerizationGO:005125840.177
regulation of protein transportGO:005122330.176
regulation of protein complex assemblyGO:004325430.170
nitrogen compound metabolic processGO:00068073190.167
positive regulation of secretion by cellGO:190353210.163
antimicrobial humoral responseGO:001973020.154
positive regulation of transportGO:005105020.150
defense responseGO:0006952470.148
regulation of establishment of protein localizationGO:007020140.146
signal transductionGO:00071654550.146
regulation of production of molecular mediator of immune responseGO:000270010.141
response to other organismGO:0051707970.139
cellular response to chemical stimulusGO:00708871570.137
regulation of protein polymerizationGO:003227120.132
regulation of cell differentiationGO:00455951420.130
positive regulation of cytokine productionGO:000181920.128
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.127
multi organism processGO:00517041340.126
ameboidal type cell migrationGO:00016671430.124
response to external stimulusGO:00096052640.123
actin filament polymerizationGO:003004120.122
macromolecular complex assemblyGO:0065003350.116
response to stressGO:00069502630.115
actin polymerization or depolymerizationGO:000815420.113
positive regulation of cellular component biogenesisGO:004408930.113
positive regulation of secretionGO:005104710.112
response to biotic stimulusGO:0009607970.112
cellular component movementGO:00069283350.111
digestive system developmentGO:00551232890.109
response to bacteriumGO:0009617580.106
positive regulation of innate immune responseGO:004508980.106
spermatid differentiationGO:004851520.106
negative regulation of biological processGO:00485193040.102
positive regulation of cellular processGO:00485222010.102
positive regulation of nitrogen compound metabolic processGO:0051173690.102
cognitionGO:005089010.102
immune responseGO:0006955280.101
superoxide metabolic processGO:000680120.101
defense response to other organismGO:0098542330.101
regulation of signal transductionGO:00099662250.100
spermatid developmentGO:000728620.100
cell migrationGO:00164772370.098
negative regulation of i kappab kinase nf kappab signalingGO:004312410.097
regulation of biological qualityGO:00650082630.097
protein secretionGO:000930610.096
defense response to virusGO:0051607100.095
regulation of multicellular organismal processGO:00512392770.095
regulation of metabolic processGO:00192223590.091
positive regulation of cytoskeleton organizationGO:005149530.090
regulation of response to biotic stimulusGO:000283120.090
innate immune responseGO:0045087130.090
tube morphogenesisGO:00352393490.090
cellular biosynthetic processGO:00442492860.089
cellular nitrogen compound biosynthetic processGO:00442712180.087
regulation of programmed cell deathGO:00430671010.086
regulation of nucleobase containing compound metabolic processGO:00192192500.086
nucleic acid metabolic processGO:00903042440.086
positive regulation of immune effector processGO:000269930.083
regulation of innate immune responseGO:0045088110.080
production of molecular mediator of immune responseGO:000244020.079
response to drugGO:004249330.079
digestive tract developmentGO:00485652650.079
regulation of macromolecule metabolic processGO:00602553170.079
embryonic organ developmentGO:00485683810.077
cellular nitrogen compound metabolic processGO:00346412900.076
cellular macromolecule metabolic processGO:00442603910.075
cell surface receptor signaling pathwayGO:00071663250.075
organic cyclic compound biosynthetic processGO:19013622230.075
regulation of primary metabolic processGO:00800903110.075
regulation of cell communicationGO:00106462320.073
regulation of defense response to virusGO:005068820.073
positive regulation of immune responseGO:0050778110.073
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.072
sensory perception of chemical stimulusGO:000760630.072
cellular response to lipopolysaccharideGO:007122230.072
leukocyte proliferationGO:007066110.072
central nervous system developmentGO:00074173870.072
regulation of cell deathGO:00109411030.071
positive regulation of protein complex assemblyGO:003133420.071
defense response to bacteriumGO:0042742220.071
regulation of cellular biosynthetic processGO:00313262450.069
biosynthetic processGO:00090582940.069
brain developmentGO:00074202930.069
reactive oxygen species metabolic processGO:007259360.069
programmed cell deathGO:00125011190.068
regulation of cell projection assemblyGO:006049140.068
response to alkaloidGO:004327920.067
positive regulation of biological processGO:00485182530.067
organonitrogen compound metabolic processGO:1901564740.067
organic substance biosynthetic processGO:19015762890.066
deathGO:00162651210.066
positive regulation of apoptotic processGO:0043065290.066
negative regulation of cellular processGO:00485232830.065
regulation of cysteine type endopeptidase activityGO:2000116210.065
heterocycle metabolic processGO:00464832900.062
regulation of extrinsic apoptotic signaling pathwayGO:200123630.062
nucleobase containing compound metabolic processGO:00061392740.061
positive regulation of macromolecule metabolic processGO:0010604930.061
positive regulation of metabolic processGO:00098931080.061
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.059
cell morphogenesisGO:00009022890.059
larval developmentGO:000216420.058
positive regulation of cellular metabolic processGO:0031325940.058
regulation of reactive oxygen species metabolic processGO:200037720.058
regulation of cell activationGO:005086510.058
regulation of signalingGO:00230512350.057
guanosine containing compound catabolic processGO:190106920.057
regulation of cellular metabolic processGO:00313233200.057
regulation of filopodium assemblyGO:005148920.056
regulation of circadian rhythmGO:004275240.055
gene expressionGO:00104672520.055
agingGO:000756820.054
embryo development ending in birth or egg hatchingGO:00097922710.053
regulation of macromolecule biosynthetic processGO:00105562250.053
organic cyclic compound metabolic processGO:19013603010.053
rna biosynthetic processGO:00327741810.052
myoblast fusionGO:0007520100.052
cell deathGO:00082191210.052
regulation of nitrogen compound metabolic processGO:00511712510.052
regulation of response to cytokine stimulusGO:006075930.051
rna metabolic processGO:00160702190.051
cell motilityGO:00488702440.051
regulation of biosynthetic processGO:00098892500.051
positive regulation of immune system processGO:0002684170.050
phagocytosisGO:000690930.049
negative regulation of protein phosphorylationGO:000193340.048
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.048
regulation of wound healingGO:006104120.048
response to organic substanceGO:00100331530.047
cellular response to organic substanceGO:00713101050.047
cellular aromatic compound metabolic processGO:00067252950.046
intracellular signal transductionGO:0035556850.046
organelle organizationGO:00069962270.045
interferon beta productionGO:003260810.045
negative regulation of protein serine threonine kinase activityGO:007190120.045
myotube differentiationGO:0014902450.045
regulation of peptidyl tyrosine phosphorylationGO:005073010.044
regulation of immune responseGO:0050776140.044
protein metabolic processGO:00195381830.044
cellular protein metabolic processGO:00442671290.044
aromatic compound biosynthetic processGO:00194382170.044
proteolysisGO:0006508380.043
maintenance of locationGO:005123540.043
response to lipopolysaccharideGO:0032496130.043
defense response to gram negative bacteriumGO:005082980.043
negative regulation of kinase activityGO:003367340.043
positive regulation of apoptotic signaling pathwayGO:200123510.042
regulation of nucleic acid templated transcriptionGO:19035062130.042
regulation of nucleoside metabolic processGO:000911820.042
regulation of interferon beta productionGO:003264810.042
cellular component biogenesisGO:00440851780.042
regulation of transcription dna templatedGO:00063552130.041
positive regulation of gtp catabolic processGO:003312610.041
regulation of type i interferon productionGO:003247920.041
negative regulation of protein kinase activityGO:000646940.041
protein complex biogenesisGO:0070271300.041
gtp metabolic processGO:004603940.041
regulation of peptidase activityGO:0052547230.040
immune system processGO:00023762410.040
regulation of endopeptidase activityGO:0052548230.040
cellular component morphogenesisGO:00329893360.040
regulation of purine nucleotide catabolic processGO:003312120.039
peripheral nervous system neuron differentiationGO:0048934280.039
morphogenesis of an epitheliumGO:00020093330.039
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.039
transcription dna templatedGO:00063511810.038
gland developmentGO:00487321430.038
negative regulation of metabolic processGO:0009892860.038
cellular response to external stimulusGO:007149620.038
guanosine containing compound metabolic processGO:190106840.038
embryonic cranial skeleton morphogenesisGO:0048701900.038
response to ethanolGO:004547160.037
macromolecule biosynthetic processGO:00090592270.036
positive regulation of response to stimulusGO:0048584800.035
regulation of developmental processGO:00507932470.035
locomotionGO:00400113130.035
stem cell proliferationGO:007208940.035
regulation of circadian sleep wake cycleGO:004274910.035
transportGO:00068102200.034
skeletal system developmentGO:00015011810.034
mononuclear cell proliferationGO:003294310.033
regulation of rho protein signal transductionGO:003502320.033
negative regulation of macromolecule metabolic processGO:0010605760.033
immune effector processGO:0002252230.033
cellular protein complex assemblyGO:0043623190.033
stem cell differentiationGO:00488631170.032
circadian sleep wake cycle sleepGO:005080210.032
multicellular organism growthGO:003526440.032
regulation of immune system processGO:0002682340.032
positive regulation of programmed cell deathGO:0043068290.032
positive regulation of cysteine type endopeptidase activityGO:2001056100.032
single organism metabolic processGO:00447102170.031
amine metabolic processGO:000930820.031
establishment of localizationGO:00512342440.031
cellular macromolecular complex assemblyGO:0034622240.031
response to mechanical stimulusGO:0009612240.031
regulation of defense responseGO:0031347140.030
positive regulation of cell activationGO:005086710.030
positive regulation of defense responseGO:003134990.030
response to lipidGO:0033993600.030
regulation of muscle contractionGO:000693730.030
muscle structure developmentGO:00610611960.030
mesenchyme developmentGO:00604851270.029
leukocyte activationGO:0045321120.029
positive regulation of multi organism processGO:004390230.029
regulation of hydrolase activityGO:0051336280.029
regulation of response to stressGO:0080134360.029
positive regulation of biosynthetic processGO:0009891680.029
regulation of circadian sleep wake cycle sleepGO:004518710.029
lipid storageGO:001991510.028
gtp catabolic processGO:000618420.028
regulation of response to stimulusGO:00485832690.028
inositol lipid mediated signalingGO:004801720.028
negative regulation of cytokine productionGO:000181810.028
positive regulation of myeloid cell differentiationGO:004563920.028
positive regulation of rna biosynthetic processGO:1902680570.028
determination of bilateral symmetryGO:00098552040.028
regulation of gene expressionGO:00104682650.028
protein targeting to nucleusGO:004474430.028
response to coldGO:000940940.027
leukocyte homeostasisGO:000177620.027
positive regulation of cellular biosynthetic processGO:0031328680.027
autophagyGO:000691440.027
positive regulation of cell deathGO:0010942290.027
cell morphogenesis involved in differentiationGO:00009041950.027
protein import into nucleusGO:000660630.027
regulation of cellular protein metabolic processGO:0032268520.027
negative regulation of gene expressionGO:0010629650.027
response to temperature stimulusGO:0009266150.027
response to xenobiotic stimulusGO:0009410450.026
regulation of gtp catabolic processGO:003312420.026
response to nicotineGO:003509420.026
localization of cellGO:00516742440.026
stem cell maintenanceGO:001982740.026
protein localization to nucleusGO:003450430.026
regulation of proteolysisGO:0030162240.026
negative regulation of cell deathGO:0060548600.026
apoptotic processGO:00069151160.026
neurological system processGO:0050877620.025
regulation of multicellular organism growthGO:004001440.025
macromolecular complex subunit organizationGO:0043933740.025
odontogenesis of dentin containing toothGO:004247510.025
cellular component assemblyGO:00226071700.025
regulation of cytokine mediated signaling pathwayGO:000195930.025
positive regulation of hydrolase activityGO:0051345130.025
positive regulation of cell communicationGO:0010647560.025
response to decreased oxygen levelsGO:0036293250.025
regulation of rna biosynthetic processGO:20011412130.025
cell projection assemblyGO:0030031640.025
phosphorus metabolic processGO:00067931090.025
regulation of protein localization to nucleusGO:190018020.025
positive regulation of endopeptidase activityGO:0010950100.025
extrinsic apoptotic signaling pathwayGO:009719130.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
blood vessel developmentGO:00015682460.024
positive regulation of catabolic processGO:000989640.024
regulation of nucleotide catabolic processGO:003081120.024
mitochondrion organizationGO:000700540.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.024
regulation of apoptotic processGO:0042981980.024
muscle cell differentiationGO:00426921390.024
cellular localizationGO:0051641970.024
response to transition metal nanoparticleGO:1990267280.023
cellular amine metabolic processGO:004410620.023
lymphocyte proliferationGO:004665110.023
tissue remodelingGO:004877140.023
generation of neuronsGO:00486993850.023
regulation of cellular ketone metabolic processGO:001056570.023
macromolecule localizationGO:0033036540.022
defense response to fungusGO:005083220.022
negative regulation of nuclear divisionGO:005178430.022
chordate embryonic developmentGO:00430092710.022
regulation of behaviorGO:0050795240.022
keratinocyte differentiationGO:003021600.022
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of multicellular organismal developmentGO:20000262230.022
signal transduction in absence of ligandGO:003803410.022
positive regulation of multicellular organismal processGO:0051240520.022
somatic muscle developmentGO:000752540.021
regulation of intracellular signal transductionGO:1902531570.021
regulation of catalytic activityGO:0050790550.021
peripheral nervous system neuron developmentGO:0048935220.021
regulation of synapse organizationGO:005080730.021
protein complex assemblyGO:0006461300.021
establishment of protein localization to organelleGO:007259440.020
specification of symmetryGO:00097992040.020
regulation of cytoplasmic transportGO:190364940.020
response to molecule of bacterial originGO:0002237140.020
positive regulation of stress activated mapk cascadeGO:003287430.020
system processGO:00030081850.020
negative regulation of rna metabolic processGO:0051253480.020
regulation of cell shapeGO:000836010.020
positive regulation of nucleotide catabolic processGO:003081310.020
cellular response to molecule of bacterial originGO:007121930.020
developmental programmed cell deathGO:001062340.020
regulation of protein catabolic processGO:004217610.020
single organism nuclear importGO:190259330.020
regulation of bindingGO:005109830.020
protein processingGO:0016485120.020
regulation of synapse assemblyGO:005196330.020
negative regulation of cell communicationGO:0010648960.020
regulation of gtpase activityGO:004308720.019
neural crest cell differentiationGO:0014033720.019
regulation of cellular amine metabolic processGO:003323800.019
striated muscle cell differentiationGO:00511461290.019
regulation of erk1 and erk2 cascadeGO:007037240.019
regulation of anatomical structure morphogenesisGO:00226031300.019
regulation of stem cell differentiationGO:200073640.019
meiotic nuclear divisionGO:000712640.019
gastrulationGO:00073692080.019
mesenchymal cell differentiationGO:0048762870.019
heart processGO:0003015710.018
positive regulation of molecular functionGO:0044093330.018
positive regulation of peptidase activityGO:0010952100.018
regulation of protein metabolic processGO:0051246560.018
nucleic acid templated transcriptionGO:00976591810.018
response to inorganic substanceGO:0010035380.018
cell projection morphogenesisGO:00488582440.018
positive regulation of cellular catabolic processGO:003133130.018
heart morphogenesisGO:00030071560.018
regulation of mitochondrion organizationGO:001082110.018
circadian sleep wake cycle processGO:002241020.017
cell activationGO:0001775160.017
actin filament based movementGO:003004810.017
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
response to endoplasmic reticulum stressGO:003497660.017
cellular protein modification processGO:00064641000.017
cellular ketone metabolic processGO:0042180110.017
positive regulation of dna metabolic processGO:005105410.017
eye developmentGO:00016542770.017
regulation of protein import into nucleusGO:004230620.017
cellular response to biotic stimulusGO:007121630.017
positive regulation of signalingGO:0023056560.017
positive regulation of gtpase activityGO:004354710.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
negative regulation of signal transductionGO:0009968940.017
regulation of response to external stimulusGO:0032101310.017
toxin metabolic processGO:000940410.017
hormone secretionGO:004687920.017
midbrain developmentGO:0030901280.017
regulation of nucleocytoplasmic transportGO:004682220.017
cellular response to stressGO:0033554620.017
negative regulation of response to stimulusGO:00485851040.017
positive regulation of cell adhesionGO:004578510.016
cellular component disassemblyGO:002241110.016
regulation of protein targetingGO:190353320.016
hemopoiesisGO:00300971830.016
small gtpase mediated signal transductionGO:000726480.016
detection of chemical stimulus involved in sensory perceptionGO:005090730.016
humoral immune responseGO:000695950.016
syncytium formationGO:0006949120.016
head developmentGO:00603223030.016
purine containing compound metabolic processGO:0072521290.016
protein heterooligomerizationGO:005129110.016
regulation of blood coagulationGO:003019310.016
nuclear transportGO:005116940.016
protein importGO:001703830.016
establishment of protein localization to plasma membraneGO:009000210.016
embryonic heart tube morphogenesisGO:00031431080.016
regulation of autophagyGO:001050630.016
regulation of intracellular protein transportGO:003315730.016
regulation of localizationGO:00328791040.016
lymph vessel developmentGO:0001945270.016
membrane raft organizationGO:003157910.016
cell cycle processGO:0022402530.015
nephron morphogenesisGO:007202820.015
response to uvGO:000941130.015
embryonic skeletal system developmentGO:0048706970.015
camera type eye developmentGO:00430102220.015
central nervous system myelin formationGO:003228910.015
antibacterial humoral responseGO:001973120.015
regulation of cellular component organizationGO:0051128860.015
ras protein signal transductionGO:000726570.015
muscle cell migrationGO:001481240.015
regulation of molecular functionGO:0065009700.015
negative regulation of programmed cell deathGO:0043069580.015
positive regulation of nucleoside metabolic processGO:004597910.015
protein localization to plasma membraneGO:007265910.015
nucleocytoplasmic transportGO:000691340.015
protein complex disassemblyGO:004324110.015
peripheral nervous system developmentGO:0007422550.015
regulation of immune effector processGO:000269750.015
positive regulation of cell matrix adhesionGO:000195410.015
regulation of anatomical structure sizeGO:0090066330.015
myeloid cell differentiationGO:0030099860.015
syncytium formation by plasma membrane fusionGO:0000768120.015
positive regulation of jnk cascadeGO:004633030.014
regulation of reproductive processGO:200024140.014
regulation of transportGO:0051049450.014
regulation of rna metabolic processGO:00512522240.014
response to oxygen levelsGO:0070482250.014
synaptic growth at neuromuscular junctionGO:005112420.014
phosphate containing compound metabolic processGO:00067961080.014
amide biosynthetic processGO:004360410.014
regulation of dna replicationGO:000627530.014
positive regulation of cellular protein metabolic processGO:0032270220.014
endocrine processGO:005088620.014
protein phosphorylationGO:0006468470.014
protein complex localizationGO:003150310.014
positive regulation of catalytic activityGO:0043085250.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
myeloid cell homeostasisGO:0002262560.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
vasculature developmentGO:00019442780.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
proteasomal protein catabolic processGO:001049820.013
establishment of localization in cellGO:0051649770.013
circulatory system processGO:0003013870.013
carboxylic acid metabolic processGO:0019752220.013
nuclear importGO:005117030.013
regulation of metal ion transportGO:001095940.013
positive regulation of proteolysisGO:0045862100.013
macromolecule modificationGO:00434121110.013
single organism localizationGO:19025782250.013
positive regulation of cell cycleGO:004578730.013
epithelial tube morphogenesisGO:00605621480.013
protein maturationGO:0051604120.013
rho protein signal transductionGO:000726650.013
negative regulation of apoptotic processGO:0043066550.013
apoptotic process involved in developmentGO:190274220.013
regulation of rac protein signal transductionGO:003502010.013
heterocycle biosynthetic processGO:00181302150.013
adult behaviorGO:003053420.013
neurotransmitter transportGO:000683620.013
negative regulation of signalingGO:0023057960.013
neural crest cell migrationGO:0001755420.013
germ line stem cell maintenanceGO:003071820.013
cellular response to radiationGO:007147840.013
hatching gland developmentGO:004878530.012
positive regulation of muscle organ developmentGO:004863610.012
protein dephosphorylationGO:000647030.012
neuroblast proliferationGO:000740520.012
regulation of endocrine processGO:004406020.012
modification dependent macromolecule catabolic processGO:004363230.012
negative regulation of cellular biosynthetic processGO:0031327550.012
ribonucleoside monophosphate catabolic processGO:000915840.012
neutrophil mediated immunityGO:000244610.012
regulation of inflammatory responseGO:005072720.012
positive regulation of protein metabolic processGO:0051247230.012
protein depolymerizationGO:005126110.012
negative regulation of mapk cascadeGO:004340940.012
glial cell migrationGO:000834730.012
organonitrogen compound biosynthetic processGO:1901566470.012
cellular amino acid metabolic processGO:000652070.012
determination of left right symmetryGO:00073681790.012
cranial ganglion developmentGO:006155030.012
erk1 and erk2 cascadeGO:007037140.012
convergent extension involved in gastrulationGO:0060027710.012
negative regulation of multicellular organismal processGO:0051241690.012
kidney developmentGO:0001822920.012
regulation of tube sizeGO:003515020.012
b cell activationGO:004211320.012
sensory perceptionGO:0007600390.012
interspecies interaction between organismsGO:004441940.012
gas transportGO:001566930.012
neuron neuron synaptic transmissionGO:000727010.012
viral processGO:001603210.011
protein complex subunit organizationGO:0071822460.011
heart contractionGO:0060047710.011
positive regulation of cellular amine metabolic processGO:003324000.011
secondary metabolic processGO:001974830.011
meiotic chromosome segregationGO:004513230.011
protein localizationGO:0008104400.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
regulation of striated muscle contractionGO:000694220.011
digestive tract morphogenesisGO:00485462310.011
regulation of phosphorus metabolic processGO:0051174430.011
response to endogenous stimulusGO:0009719830.011
spindle assemblyGO:005122520.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
peptide transportGO:001583310.011
regulation of blood vessel sizeGO:005088020.011
apoptotic process involved in morphogenesisGO:006056120.011
regulation of cell matrix adhesionGO:000195210.011
reproductionGO:0000003400.011
sympathetic nervous system developmentGO:004848530.011
cell part morphogenesisGO:00329902460.011
negative chemotaxisGO:005091910.011
nucleobase containing compound biosynthetic processGO:00346542050.011
response to topologically incorrect proteinGO:003596620.011
single organism organelle organizationGO:19025891990.011

caspa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
immune system diseaseDOID:291400.020
nervous system diseaseDOID:86300.017
cardiovascular system diseaseDOID:128700.013
disease of metabolismDOID:001466700.011