Danio rerio

37 known processes

her4.3

hairy-related 4.3

(Aliases: si:ch73-21g5.4,her4.1,MGC173865,MGC174755)

her4.3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.083
heterocycle metabolic processGO:00464832900.054
Rat Fly
autophagyGO:000691440.051
agingGO:000756820.051
cellular aromatic compound metabolic processGO:00067252950.047
Rat Fly
cellular macromolecule metabolic processGO:00442603910.042
Rat Fly
proteolysis involved in cellular protein catabolic processGO:005160330.042
positive regulation of transportGO:005105020.042
regulation of multicellular organism growthGO:004001440.041
cellular protein catabolic processGO:004425740.040
modification dependent protein catabolic processGO:001994130.039
cellular nitrogen compound metabolic processGO:00346412900.038
Rat Fly
signal transductionGO:00071654550.038
Human
nucleobase containing compound metabolic processGO:00061392740.038
Rat Fly
regulation of multicellular organismal processGO:00512392770.037
Rat Fly
multicellular organism growthGO:003526440.037
regulation of cytokine productionGO:000181730.036
positive regulation of cell cycleGO:004578730.036
establishment of protein localization to organelleGO:007259440.036
cell surface receptor signaling pathwayGO:00071663250.036
Human
ubiquitin dependent protein catabolic processGO:000651130.035
regulation of gene expressionGO:00104682650.035
Rat Fly
regulation of macromolecule metabolic processGO:00602553170.035
Rat Fly
response to drugGO:004249330.034
negative regulation of biological processGO:00485193040.034
Human Rat Fly
stem cell maintenanceGO:001982740.034
Human Rat
modification dependent macromolecule catabolic processGO:004363230.033
regulation of protein transportGO:005122330.033
regulation of cellular metabolic processGO:00313233200.033
Rat Fly
regulation of biosynthetic processGO:00098892500.032
Rat Fly
guanosine containing compound catabolic processGO:190106920.032
regulation of bindingGO:005109830.032
response to chemicalGO:00422213200.032
regulation of cellular biosynthetic processGO:00313262450.032
Rat Fly
organic cyclic compound metabolic processGO:19013603010.032
Rat Fly
nitrogen compound metabolic processGO:00068073190.032
Rat Fly
embryonic organ developmentGO:00485683810.032
maintenance of locationGO:005123540.032
vasculature developmentGO:00019442780.032
regulation of metabolic processGO:00192223590.031
Rat Fly
phagocytosisGO:000690930.031
regulation of establishment of protein localizationGO:007020140.031
biosynthetic processGO:00090582940.031
Rat Fly
regulation of autophagyGO:001050630.031
single organism metabolic processGO:00447102170.030
single organism membrane fusionGO:004480120.030
cellular response to external stimulusGO:007149620.030
regulation of developmental processGO:00507932470.030
Human Rat Fly
nucleocytoplasmic transportGO:000691340.030
blood vessel developmentGO:00015682460.030
positive regulation of catabolic processGO:000989640.030
proteasomal protein catabolic processGO:001049820.029
chordate embryonic developmentGO:00430092710.029
positive regulation of cellular component biogenesisGO:004408930.029
negative regulation of protein phosphorylationGO:000193340.029
immune system processGO:00023762410.029
Rat
gtp metabolic processGO:004603940.029
cellular biosynthetic processGO:00442492860.029
Rat Fly
regulation of intracellular protein transportGO:003315730.029
regulation of rna metabolic processGO:00512522240.028
Rat Fly
cognitionGO:005089010.028
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
positive regulation of cellular catabolic processGO:003133130.028
lipid storageGO:001991510.028
negative regulation of protein kinase activityGO:000646940.028
membrane fusionGO:006102520.028
organic cyclic compound biosynthetic processGO:19013622230.027
Rat Fly
organic substance biosynthetic processGO:19015762890.027
Rat Fly
regulation of primary metabolic processGO:00800903110.027
Rat Fly
positive regulation of cytokine productionGO:000181920.027
leukocyte proliferationGO:007066110.027
regulation of protein ubiquitinationGO:003139630.027
cell morphogenesisGO:00009022890.027
protein targeting to nucleusGO:004474430.027
regulation of protein modification by small protein conjugation or removalGO:190332030.027
nuclear transportGO:005116940.026
negative regulation of cellular processGO:00485232830.026
Human Rat Fly
regulation of extrinsic apoptotic signaling pathwayGO:200123630.026
cellular component movementGO:00069283350.026
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.026
positive regulation of map kinase activityGO:004340630.026
regulation of neural precursor cell proliferationGO:200017730.026
Fly
heterocycle biosynthetic processGO:00181302150.026
Rat Fly
regulation of protein catabolic processGO:004217610.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
Rat Fly
gene expressionGO:00104672520.025
Rat Fly
regulation of cell shapeGO:000836010.025
regulation of macromolecule biosynthetic processGO:00105562250.025
Rat Fly
regulation of nucleocytoplasmic transportGO:004682220.025
amine metabolic processGO:000930820.025
i kappab kinase nf kappab signalingGO:000724940.025
regulation of reactive oxygen species metabolic processGO:200037720.025
regionalizationGO:00030022740.025
Fly
regulation of synaptic plasticityGO:004816710.025
regulation of protein complex assemblyGO:004325430.025
regulation of nucleic acid templated transcriptionGO:19035062130.025
Rat Fly
single organism nuclear importGO:190259330.024
macromolecule biosynthetic processGO:00090592270.024
Rat Fly
response to stressGO:00069502630.024
Fly
regulation of metal ion transportGO:001095940.024
regulation of protein localization to nucleusGO:190018020.024
regulation of protein targetingGO:190353320.024
tissue remodelingGO:004877140.024
nucleic acid metabolic processGO:00903042440.024
Rat Fly
positive regulation of stress activated mapk cascadeGO:003287430.023
cellular response to molecule of bacterial originGO:007121930.023
mitochondrion organizationGO:000700540.023
nuclear importGO:005117030.023
protein import into nucleusGO:000660630.023
cellular amine metabolic processGO:004410620.023
positive regulation of jnk cascadeGO:004633030.023
regulation of nitrogen compound metabolic processGO:00511712510.023
Rat Fly
gtp catabolic processGO:000618420.023
system processGO:00030081850.023
Fly
brain developmentGO:00074202930.023
Rat Fly
aromatic compound biosynthetic processGO:00194382170.023
Rat Fly
positive regulation of i kappab kinase nf kappab signalingGO:004312330.022
rna biosynthetic processGO:00327741810.022
Rat Fly
positive regulation of secretionGO:005104710.022
regulation of cytoplasmic transportGO:190364940.022
regulation of muscle contractionGO:000693730.022
rna metabolic processGO:00160702190.022
Rat Fly
regulation of response to stimulusGO:00485832690.022
Fly
positive regulation of biological processGO:00485182530.022
Human Fly
regulation of protein bindingGO:004339330.022
response to external stimulusGO:00096052640.022
Fly
blood vessel morphogenesisGO:00485142160.022
regulation of protein import into nucleusGO:004230620.022
protein metabolic processGO:00195381830.022
organic acid metabolic processGO:0006082310.021
negative regulation of kinase activityGO:003367340.021
somitogenesisGO:0001756870.021
cytokinesisGO:000091030.021
extrinsic apoptotic signaling pathwayGO:009719130.021
organelle fusionGO:004828430.021
cellular response to starvationGO:000926710.021
cellular component biogenesisGO:00440851780.021
protein localization to nucleusGO:003450430.021
single organism organelle organizationGO:19025891990.021
cellular response to lipopolysaccharideGO:007122230.021
cellular ketone metabolic processGO:0042180110.021
response to abiotic stimulusGO:00096281220.021
internal protein amino acid acetylationGO:000647520.021
sensory organ developmentGO:00074233930.021
Fly
peptidyl serine modificationGO:001820920.021
adult behaviorGO:003053420.021
central nervous system developmentGO:00074173870.021
Rat Fly
positive regulation of cellular processGO:00485222010.021
Human Fly
regulation of cellular amino acid metabolic processGO:000652100.020
positive regulation of translationGO:004572710.020
regulation of biological qualityGO:00650082630.020
regulation of reproductive processGO:200024140.020
mononuclear cell proliferationGO:003294310.020
response to organic substanceGO:00100331530.020
heart developmentGO:00075073130.020
positive regulation of secretion by cellGO:190353210.020
oxoacid metabolic processGO:0043436310.020
b cell activationGO:004211320.020
carbohydrate homeostasisGO:003350010.020
cellular response to extracellular stimulusGO:003166820.020
response to carbohydrateGO:000974330.020
embryo development ending in birth or egg hatchingGO:00097922710.020
nucleobase containing compound biosynthetic processGO:00346542050.020
Rat Fly
regulation of signalingGO:00230512350.019
cellular response to nutrient levelsGO:003166920.019
synaptic growth at neuromuscular junctionGO:005112420.019
regulation of cell activationGO:005086510.019
programmed cell deathGO:00125011190.019
cell projection organizationGO:00300302840.019
generation of neuronsGO:00486993850.019
establishment of localizationGO:00512342440.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
purine nucleoside monophosphate catabolic processGO:000912840.019
phagocytosis engulfmentGO:000691110.019
anterior posterior pattern specificationGO:00099521520.019
cellular carbohydrate metabolic processGO:004426240.019
regulation of cellular ketone metabolic processGO:001056570.019
regulation of cellular amine metabolic processGO:003323800.019
guanosine containing compound metabolic processGO:190106840.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
Rat Fly
organelle organizationGO:00069962270.019
head developmentGO:00603223030.019
Rat Fly
meiotic cell cycle processGO:190304630.018
peptidyl lysine acetylationGO:001839420.018
intracellular signal transductionGO:0035556850.018
microtubule organizing center organizationGO:003102310.018
atp catabolic processGO:000620040.018
angiogenesisGO:00015251580.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
meiotic nuclear divisionGO:000712640.018
protein acetylationGO:000647320.018
regulation of meiotic cell cycleGO:005144510.018
protein importGO:001703830.018
nucleoside monophosphate catabolic processGO:000912540.018
cellular component morphogenesisGO:00329893360.018
cellular protein metabolic processGO:00442671290.018
internal peptidyl lysine acetylationGO:001839320.018
transcription dna templatedGO:00063511810.018
Rat Fly
small molecule metabolic processGO:0044281770.017
positive regulation of protein complex assemblyGO:003133420.017
cellular response to biotic stimulusGO:007121630.017
carboxylic acid metabolic processGO:0019752220.017
negative regulation of multicellular organismal processGO:0051241690.017
Rat
regulation of cell communicationGO:00106462320.017
cell projection morphogenesisGO:00488582440.017
cell motilityGO:00488702440.017
transportGO:00068102200.017
membrane invaginationGO:001032410.017
cell cycle g1 s phase transitionGO:004484310.017
centrosome organizationGO:005129710.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
cellular response to radiationGO:007147840.017
growthGO:00400071740.017
cellular macromolecule biosynthetic processGO:00346452240.017
Rat Fly
negative regulation of catabolic processGO:000989530.017
production of molecular mediator of immune responseGO:000244020.017
regulation of organelle assemblyGO:190211540.017
regulation of multicellular organismal developmentGO:20000262230.017
Rat Fly
stem cell divisionGO:001714510.017
response to lipidGO:0033993600.016
locomotor rhythmGO:004547530.016
ribonucleoside monophosphate catabolic processGO:000915840.016
determination of bilateral symmetryGO:00098552040.016
regulation of cell differentiationGO:00455951420.016
Human Rat Fly
protein secretionGO:000930610.016
response to corticosteroidGO:003196010.016
regulation of signal transductionGO:00099662250.016
locomotionGO:00400113130.016
Fly
cell migrationGO:00164772370.016
regulation of nucleoside metabolic processGO:000911820.016
hormone secretionGO:004687920.016
response to glucocorticoidGO:005138410.016
peptide transportGO:001583310.016
secondary metabolic processGO:001974830.016
cell part morphogenesisGO:00329902460.016
regulation of cellular protein catabolic processGO:190336210.016
exocytosisGO:000688710.016
protein acylationGO:004354330.016
cellular component assemblyGO:00226071700.016
cytoskeleton dependent cytokinesisGO:006164030.016
stem cell proliferationGO:007208940.016
Fly
neuron differentiationGO:00301823530.016
blood circulationGO:0008015870.016
lymphocyte proliferationGO:004665110.016
regulation of mrna processingGO:005068430.016
response to uvGO:000941130.015
antimicrobial humoral responseGO:001973020.015
carbohydrate biosynthetic processGO:001605110.015
cellular protein modification processGO:00064641000.015
regulation of purine nucleotide catabolic processGO:003312120.015
regulation of production of molecular mediator of immune responseGO:000270010.015
specification of symmetryGO:00097992040.015
regulation of blood pressureGO:000821710.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
positive regulation of cell activationGO:005086710.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
hormone transportGO:000991420.015
protein stabilizationGO:005082120.015
rna localizationGO:000640340.015
protein localization to plasma membraneGO:007265910.015
multi organism processGO:00517041340.015
negative regulation of macromolecule metabolic processGO:0010605760.015
Rat Fly
glucose homeostasisGO:004259310.015
positive regulation of cytoskeleton organizationGO:005149530.015
somite developmentGO:0061053960.015
heart contractionGO:0060047710.015
embryonic organ morphogenesisGO:00485622740.015
regulation of rna biosynthetic processGO:20011412130.015
Rat Fly
regulation of inflammatory responseGO:005072720.015
response to hexoseGO:000974630.015
organonitrogen compound metabolic processGO:1901564740.015
response to monosaccharideGO:003428430.015
cellular amino acid metabolic processGO:000652070.015
heart processGO:0003015710.015
negative regulation of metabolic processGO:0009892860.014
Rat Fly
regulation of nucleotide catabolic processGO:003081120.014
neuroblast proliferationGO:000740520.014
Fly
peptidyl serine phosphorylationGO:001810510.014
nucleic acid templated transcriptionGO:00976591810.014
Rat Fly
regulation of circadian rhythmGO:004275240.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regulation of dendrite developmentGO:005077330.014
protein modification processGO:00362111000.014
developmental growthGO:00485891660.014
localization of cellGO:00516742440.014
apoptotic processGO:00069151160.014
cellular response to chemical stimulusGO:00708871570.014
single organism localizationGO:19025782250.014
negative regulation of cytokine productionGO:000181810.014
positive regulation of cellular amine metabolic processGO:003324000.014
muscle structure developmentGO:00610611960.014
response to nutrientGO:000758430.014
connective tissue developmentGO:0061448990.014
Human
macromolecule modificationGO:00434121110.014
morphogenesis of an epitheliumGO:00020093330.014
cell substrate adhesionGO:003158940.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
response to endogenous stimulusGO:0009719830.014
neuron neuron synaptic transmissionGO:000727010.013
transcription from rna polymerase ii promoterGO:0006366800.013
Rat Fly
negative regulation of protein transportGO:005122430.013
regulation of gtp catabolic processGO:003312420.013
reactive oxygen species metabolic processGO:007259360.013
eye developmentGO:00016542770.013
Fly
establishment of synaptic vesicle localizationGO:009748010.013
cellular component disassemblyGO:002241110.013
signal transduction in absence of ligandGO:003803410.013
regulation of organ growthGO:004662030.013
regulation of dendrite morphogenesisGO:004881430.013
regulation of cell deathGO:00109411030.013
female gonad developmentGO:000858540.013
cellular response to organic substanceGO:00713101050.013
cell cycleGO:0007049930.013
segmentationGO:0035282970.013
regulation of wound healingGO:006104120.013
positive regulation of nucleoside metabolic processGO:004597910.013
circulatory system processGO:0003013870.013
positive regulation of cell adhesionGO:004578510.013
double strand break repairGO:000630230.013
actin filament polymerizationGO:003004120.013
synaptic vesicle transportGO:004848910.013
retina development in camera type eyeGO:00600411460.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
mesenchyme developmentGO:00604851270.013
positive regulation of nucleotide catabolic processGO:003081310.013
phosphorus metabolic processGO:00067931090.013
single organism transportGO:00447652060.013
regulation of gtpase activityGO:004308720.013
g1 s transition of mitotic cell cycleGO:000008210.013
protein polymerizationGO:005125840.013
mitochondrial transportGO:000683920.013
post embryonic organ developmentGO:004856940.013
macroautophagyGO:001623610.013
striated muscle tissue developmentGO:00147061100.012
regulation of dna replicationGO:000627530.012
embryonic skeletal system developmentGO:0048706970.012
regulation of hormone secretionGO:004688320.012
regulation of synapse organizationGO:005080730.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
Rat Fly
regulation of erk1 and erk2 cascadeGO:007037240.012
response to other organismGO:0051707970.012
muscle tissue developmentGO:00605371100.012
response to external biotic stimulusGO:0043207970.012
response to alkaloidGO:004327920.012
regulation of stem cell proliferationGO:007209120.012
Fly
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
digestive system developmentGO:00551232890.012
cellular response to stressGO:0033554620.012
Fly
positive regulation of dna metabolic processGO:005105410.012
response to glucoseGO:000974930.012
regulation of transcription dna templatedGO:00063552130.012
Rat Fly
negative regulation of protein serine threonine kinase activityGO:007190120.012
positive regulation of cellular metabolic processGO:0031325940.012
protein dephosphorylationGO:000647030.012
synaptic vesicle localizationGO:009747910.012
regulation of response to biotic stimulusGO:000283120.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
Rat Fly
adherens junction organizationGO:003433240.012
nuclear exportGO:005116810.012
single fertilizationGO:000733830.012
deathGO:00162651210.012
response to biotic stimulusGO:0009607970.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
regulation of synapse assemblyGO:005196330.012
cilium morphogenesisGO:0060271850.012
negative regulation of cytoplasmic transportGO:190365020.012
regulation of cell substrate adhesionGO:001081010.012
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
histone h3 k4 methylationGO:005156820.011
phosphate containing compound metabolic processGO:00067961080.011
axon developmentGO:00615641660.011
response to organic cyclic compoundGO:0014070510.011
erk1 and erk2 cascadeGO:007037140.011
immune system developmentGO:00025201910.011
Rat
lamellipodium organizationGO:009758110.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
regulation of cell developmentGO:00602841000.011
Rat Fly
intracellular mrna localizationGO:000829810.011
regulation of neuronal synaptic plasticityGO:004816810.011
positive regulation of neuron apoptotic processGO:004352510.011
development of primary female sexual characteristicsGO:004654540.011
negative regulation of map kinase activityGO:004340720.011
cell morphogenesis involved in differentiationGO:00009041950.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
somatic muscle developmentGO:000752540.011
negative regulation of defense responseGO:003134820.011
sleepGO:003043110.011
response to woundingGO:00096111160.011
negative regulation of intracellular transportGO:003238730.011
gland developmentGO:00487321430.011
cell matrix adhesionGO:000716040.011
regulation of programmed cell deathGO:00430671010.011
spermatid developmentGO:000728620.011
female sex differentiationGO:004666040.011
regulation of carbohydrate metabolic processGO:000610940.011
tube morphogenesisGO:00352393490.011
camera type eye developmentGO:00430102220.011
somatic stem cell maintenanceGO:003501910.011
protein heterooligomerizationGO:005129110.011
regulation of cellular component organizationGO:0051128860.011
translational initiationGO:000641330.011
response to hydrogen peroxideGO:004254230.011
dorsal ventral pattern formationGO:00099531250.011
Fly
chemosensory behaviorGO:000763510.011
determination of left right symmetryGO:00073681790.011
germ line stem cell maintenanceGO:003071820.011
long chain fatty acid metabolic processGO:000167610.011
digestive tract developmentGO:00485652650.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
Rat
cilium organizationGO:0044782710.011
cellular response to oxygen levelsGO:007145310.011
positive regulation of cell divisionGO:005178120.011
protein homooligomerizationGO:005126030.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
negative regulation of protein localization to nucleusGO:190018120.011
sensory organ morphogenesisGO:00905962000.011
Fly
heart morphogenesisGO:00030071560.011
liver developmentGO:0001889960.011
toll like receptor signaling pathwayGO:000222440.011
neurotransmitter transportGO:000683620.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
ventricular cardiac muscle tissue morphogenesisGO:005501020.010
skeletal system developmentGO:00015011810.010
Human
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
positive regulation of stem cell proliferationGO:200064810.010
Fly
action potentialGO:0001508190.010
cellular response to light stimulusGO:007148240.010
regulation of mrna splicing via spliceosomeGO:004802430.010
cellular response to hypoxiaGO:007145610.010
activation of mapk activityGO:000018730.010
mitotic cytokinesisGO:000028130.010
inner ear developmentGO:00488391260.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
negative regulation of mapk cascadeGO:004340940.010
negative regulation of cellular catabolic processGO:003133030.010
regulation of neurogenesisGO:0050767870.010
Rat Fly
cell deathGO:00082191210.010
spermatid differentiationGO:004851520.010
cellular respirationGO:004533330.010
phosphorylationGO:0016310690.010
homeostatic processGO:00425921420.010
wnt signaling pathwayGO:0016055800.010
positive regulation of metabolic processGO:00098931080.010

her4.3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
nervous system diseaseDOID:86300.032
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
sensory system diseaseDOID:005015500.016
musculoskeletal system diseaseDOID:1700.014
retinal diseaseDOID:567900.013
cardiovascular system diseaseDOID:128700.013
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
immune system diseaseDOID:291400.010