Danio rerio

37 known processes

her4.5

hairy-related 4.5

(Aliases: wu:fb74d11,si:ch73-21g5.6,cb485,sb:cb485)

her4.5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mesenchyme developmentGO:00604851270.174
neuron differentiationGO:00301823530.164
larval developmentGO:000216420.137
enzyme linked receptor protein signaling pathwayGO:00071671060.106
response to stressGO:00069502630.089
single organism metabolic processGO:00447102170.088
astrocyte differentiationGO:004870810.082
sensory organ developmentGO:00074233930.082
regulation of multicellular organismal processGO:00512392770.082
meiotic nuclear divisionGO:000712640.070
blood vessel developmentGO:00015682460.070
cellular macromolecule metabolic processGO:00442603910.069
cell cycleGO:0007049930.068
response to organic substanceGO:00100331530.066
retina development in camera type eyeGO:00600411460.059
regulation of primary metabolic processGO:00800903110.059
stem cell proliferationGO:007208940.057
generation of neuronsGO:00486993850.054
cellular component morphogenesisGO:00329893360.053
regulation of biological qualityGO:00650082630.047
mesenchymal cell developmentGO:0014031780.046
cellular protein metabolic processGO:00442671290.044
regulation of metabolic processGO:00192223590.043
cellular response to chemical stimulusGO:00708871570.043
cellular response to oxygen levelsGO:007145310.042
positive regulation of transportGO:005105020.041
regulation of macromolecule metabolic processGO:00602553170.041
multicellular organism growthGO:003526440.041
aromatic compound biosynthetic processGO:00194382170.040
apoptotic processGO:00069151160.040
negative regulation of biological processGO:00485193040.040
negative regulation of protein kinase activityGO:000646940.040
adult behaviorGO:003053420.039
regulation of meiotic cell cycleGO:005144510.038
camera type eye developmentGO:00430102220.038
cellular aromatic compound metabolic processGO:00067252950.037
regulation of multicellular organism growthGO:004001440.037
embryonic organ developmentGO:00485683810.037
response to chemicalGO:00422213200.036
response to oxygen containing compoundGO:1901700550.036
cell projection morphogenesisGO:00488582440.035
negative regulation of cellular processGO:00485232830.034
eye developmentGO:00016542770.034
gene expressionGO:00104672520.034
embryo development ending in birth or egg hatchingGO:00097922710.033
regulation of protein transportGO:005122330.033
central nervous system developmentGO:00074173870.032
oxoacid metabolic processGO:0043436310.032
protein metabolic processGO:00195381830.032
heart developmentGO:00075073130.030
regulation of synaptic plasticityGO:004816710.030
regulation of multicellular organismal developmentGO:20000262230.030
protein modification processGO:00362111000.030
maintenance of locationGO:005123540.029
neuroblast proliferationGO:000740520.029
macromolecule modificationGO:00434121110.029
stem cell differentiationGO:00488631170.028
small molecule metabolic processGO:0044281770.028
organelle organizationGO:00069962270.028
mesenchymal cell differentiationGO:0048762870.027
muscle cell developmentGO:00550011150.027
striated muscle cell developmentGO:00550021080.026
cellular biosynthetic processGO:00442492860.026
phosphorus metabolic processGO:00067931090.026
developmental growthGO:00485891660.026
regulation of neural precursor cell proliferationGO:200017730.026
positive regulation of biological processGO:00485182530.026
positive regulation of secretion by cellGO:190353210.025
regulation of establishment of protein localizationGO:007020140.025
organonitrogen compound metabolic processGO:1901564740.025
regulation of transmembrane transporter activityGO:002289820.025
angiogenesisGO:00015251580.025
negative regulation of kinase activityGO:003367340.025
skeletal system developmentGO:00015011810.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.024
cellular nitrogen compound metabolic processGO:00346412900.024
pectoral fin developmentGO:0033339500.024
signal transductionGO:00071654550.024
nucleobase containing compound metabolic processGO:00061392740.024
vasculature developmentGO:00019442780.024
carboxylic acid metabolic processGO:0019752220.024
organic acid metabolic processGO:0006082310.024
cellular response to hypoxiaGO:007145610.024
regulation of cell communicationGO:00106462320.024
deathGO:00162651210.024
brain developmentGO:00074202930.023
single organism transportGO:00447652060.023
blood vessel morphogenesisGO:00485142160.023
epithelial tube morphogenesisGO:00605621480.023
cardiac cell developmentGO:0055006210.023
positive regulation of secretionGO:005104710.023
regulation of gene expressionGO:00104682650.023
growthGO:00400071740.023
regulation of cell developmentGO:00602841000.023
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.022
positive regulation of catabolic processGO:000989640.022
cellular response to organic substanceGO:00713101050.022
pectoral fin morphogenesisGO:0035138290.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
regenerationGO:0031099910.022
protein secretionGO:000930610.021
stem cell developmentGO:0048864820.021
neuron developmentGO:00486662620.021
regulation of oligodendrocyte differentiationGO:004871310.021
negative regulation of macromolecule metabolic processGO:0010605760.021
regulation of anatomical structure morphogenesisGO:00226031300.021
agingGO:000756820.021
cell morphogenesisGO:00009022890.021
stem cell maintenanceGO:001982740.021
muscle cell differentiationGO:00426921390.021
negative regulation of mitosisGO:004583930.020
digestive system developmentGO:00551232890.020
organic cyclic compound metabolic processGO:19013603010.020
morphogenesis of an epitheliumGO:00020093330.019
regulation of circadian rhythmGO:004275240.019
positive regulation of cellular catabolic processGO:003133130.019
negative regulation of nuclear divisionGO:005178430.019
response to external stimulusGO:00096052640.019
cellular protein modification processGO:00064641000.019
mitochondrion organizationGO:000700540.019
proteasomal protein catabolic processGO:001049820.019
cellular component biogenesisGO:00440851780.018
neural crest cell differentiationGO:0014033720.018
neuron projection morphogenesisGO:00488121610.018
heart morphogenesisGO:00030071560.018
biosynthetic processGO:00090582940.018
regulation of cellular amine metabolic processGO:003323800.018
modification dependent protein catabolic processGO:001994130.018
regulation of nitrogen compound metabolic processGO:00511712510.018
response to woundingGO:00096111160.018
cellular amine metabolic processGO:004410620.018
regulation of cell deathGO:00109411030.017
phosphate containing compound metabolic processGO:00067961080.017
vasculogenesisGO:0001570410.017
response to endogenous stimulusGO:0009719830.017
camera type eye morphogenesisGO:00485931080.017
ectodermal placode morphogenesisGO:0071697320.017
organic substance biosynthetic processGO:19015762890.017
negative regulation of protein phosphorylationGO:000193340.017
regulation of protein import into nucleusGO:004230620.017
mesoderm developmentGO:0007498880.017
regulation of phosphate metabolic processGO:0019220430.017
regulation of wnt signaling pathwayGO:0030111530.017
gtp metabolic processGO:004603940.017
cell surface receptor signaling pathwayGO:00071663250.017
positive regulation of signal transductionGO:0009967560.017
heterocycle metabolic processGO:00464832900.016
regulation of axon extensionGO:0030516240.016
response to bacteriumGO:0009617580.016
regulation of cell cycleGO:0051726520.016
cytokinesisGO:000091030.016
liver developmentGO:0001889960.016
establishment of localizationGO:00512342440.016
dorsal ventral pattern formationGO:00099531250.016
regulation of cellular amino acid metabolic processGO:000652100.016
peptidyl serine phosphorylationGO:001810510.016
amine metabolic processGO:000930820.016
cognitionGO:005089010.016
cellular response to growth factor stimulusGO:0071363390.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
modification dependent macromolecule catabolic processGO:004363230.016
cellular ketone metabolic processGO:0042180110.015
negative regulation of gliogenesisGO:001401410.015
guanosine containing compound catabolic processGO:190106920.015
cellular component movementGO:00069283350.015
protein polymerizationGO:005125840.015
cellular macromolecule biosynthetic processGO:00346452240.015
regulation of cellular ketone metabolic processGO:001056570.015
transmembrane transportGO:00550851200.015
nitrogen compound metabolic processGO:00068073190.015
regulation of response to stimulusGO:00485832690.015
regulation of purine nucleotide catabolic processGO:003312120.015
positive regulation of cell divisionGO:005178120.015
tube morphogenesisGO:00352393490.015
system processGO:00030081850.015
regulation of ion transmembrane transporter activityGO:003241220.015
retina morphogenesis in camera type eyeGO:0060042790.015
regulation of vasculature developmentGO:1901342330.015
positive regulation of cytokine productionGO:000181920.015
response to carbohydrateGO:000974330.015
regulation of embryonic developmentGO:0045995470.015
immune system developmentGO:00025201910.015
regulation of protein catabolic processGO:004217610.015
determination of bilateral symmetryGO:00098552040.015
sensory organ morphogenesisGO:00905962000.015
eye morphogenesisGO:00485921440.014
single organism organelle organizationGO:19025891990.014
cellular response to decreased oxygen levelsGO:003629410.014
regulation of transporter activityGO:003240920.014
intracellular signal transductionGO:0035556850.014
cell proliferationGO:0008283800.014
gtp catabolic processGO:000618420.014
positive regulation of cell cycleGO:004578730.014
circulatory system processGO:0003013870.014
regulation of dendrite morphogenesisGO:004881430.014
positive regulation of neural precursor cell proliferationGO:200017910.014
sensory perception of painGO:001923310.014
negative regulation of collateral sproutingGO:004867120.014
glial cell proliferationGO:001400940.014
positive regulation of cellular processGO:00485222010.014
protein dephosphorylationGO:000647030.014
rna metabolic processGO:00160702190.014
single organism nuclear importGO:190259330.014
ubiquitin dependent protein catabolic processGO:000651130.014
chemosensory behaviorGO:000763510.014
response to oxygen levelsGO:0070482250.014
cellular component assemblyGO:00226071700.014
positive regulation of programmed cell deathGO:0043068290.013
sleepGO:003043110.013
regulation of metal ion transportGO:001095940.013
hepaticobiliary system developmentGO:0061008980.013
cellular response to stressGO:0033554620.013
regulation of cellular protein metabolic processGO:0032268520.013
regulation of cytoplasmic transportGO:190364940.013
regulation of cellular response to growth factor stimulusGO:0090287350.013
negative regulation of gene expressionGO:0010629650.013
striated muscle cell differentiationGO:00511461290.013
anterior posterior pattern specificationGO:00099521520.013
embryonic heart tube developmentGO:00350501330.013
transportGO:00068102200.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
positive regulation of cellular amine metabolic processGO:003324000.013
response to hypoxiaGO:0001666250.013
blood circulationGO:0008015870.013
lipid catabolic processGO:001604240.013
somite developmentGO:0061053960.012
regulation of cell differentiationGO:00455951420.012
neural crest cell developmentGO:0014032620.012
positive regulation of gtpase activityGO:004354710.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of reproductive processGO:200024140.012
regionalizationGO:00030022740.012
positive regulation of stress activated mapk cascadeGO:003287430.012
sympathetic nervous system developmentGO:004848530.012
response to uvGO:000941130.012
cellular localizationGO:0051641970.012
negative regulation of secretion by cellGO:190353120.012
protein targeting to nucleusGO:004474430.012
regulation of intracellular protein transportGO:003315730.012
ameboidal type cell migrationGO:00016671430.012
regulation of protein ubiquitinationGO:003139630.012
neuronal action potentialGO:0019228180.012
regulation of dendrite developmentGO:005077330.012
digestive tract morphogenesisGO:00485462310.012
regulation of cytokine productionGO:000181730.012
head developmentGO:00603223030.012
positive regulation of map kinase activityGO:004340630.012
response to vitaminGO:003327330.012
regulation of glial cell differentiationGO:004568540.012
digestive tract developmentGO:00485652650.012
positive regulation of apoptotic processGO:0043065290.012
cellular response to endogenous stimulusGO:0071495680.012
adherens junction organizationGO:003433240.012
cellular response to light stimulusGO:007148240.011
response to external biotic stimulusGO:0043207970.011
response to growth factorGO:0070848390.011
single organism localizationGO:19025782250.011
regulation of cell growthGO:0001558290.011
otic vesicle formationGO:0030916270.011
wnt signaling pathwayGO:0016055800.011
cellular component assembly involved in morphogenesisGO:00109271070.011
response to other organismGO:0051707970.011
protein complex localizationGO:003150310.011
meiotic chromosome segregationGO:004513230.011
regulation of gtp catabolic processGO:003312420.011
regulation of phosphorus metabolic processGO:0051174430.011
response to fibroblast growth factorGO:0071774220.011
regulation of gtpase activityGO:004308720.011
neuron neuron synaptic transmissionGO:000727010.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
regulation of inflammatory responseGO:005072720.011
cell projection organizationGO:00300302840.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
meiotic cell cycle processGO:190304630.011
developmental cell growthGO:0048588520.011
cell migrationGO:00164772370.011
regulation of nucleocytoplasmic transportGO:004682220.011
positive regulation of macromolecule metabolic processGO:0010604930.011
renal system developmentGO:0072001940.011
immune system processGO:00023762410.011
regulation of protein localization to nucleusGO:190018020.011
regulation of cell morphogenesisGO:0022604420.011
neural precursor cell proliferationGO:0061351200.010
epidermal cell fate specificationGO:000995740.010
embryonic viscerocranium morphogenesisGO:0048703520.010
regulation of angiogenesisGO:0045765260.010
regulation of cellular component organizationGO:0051128860.010
cell cycle arrestGO:000705010.010
response to monosaccharideGO:003428430.010
cell cell recognitionGO:000998810.010
regulation of microtubule depolymerizationGO:003111410.010
cell fate specificationGO:0001708680.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
cellular response to fibroblast growth factor stimulusGO:0044344220.010
nucleic acid metabolic processGO:00903042440.010
negative regulation of protein transportGO:005122430.010
multicellular organismal signalingGO:0035637220.010
regulation of ras gtpase activityGO:003231820.010
phosphorylationGO:0016310690.010
positive regulation of metabolic processGO:00098931080.010
cytoskeleton organizationGO:0007010960.010
estrogen metabolic processGO:000821020.010
response to drugGO:004249330.010
embryonic organ morphogenesisGO:00485622740.010
nucleocytoplasmic transportGO:000691340.010

her4.5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.035
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011