Danio rerio

0 known processes

pin4

protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)

(Aliases: MGC110008,zgc:110008)

pin4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.097
agingGO:000756820.069
multicellular organism growthGO:003526440.046
cellular nitrogen compound metabolic processGO:00346412900.045
organic substance biosynthetic processGO:19015762890.038
nucleocytoplasmic transportGO:000691340.038
biosynthetic processGO:00090582940.038
regulation of multicellular organism growthGO:004001440.037
establishment of protein localization to organelleGO:007259440.037
nitrogen compound metabolic processGO:00068073190.036
proteolysis involved in cellular protein catabolic processGO:005160330.035
cellular macromolecule metabolic processGO:00442603910.034
modification dependent protein catabolic processGO:001994130.033
protein acetylationGO:000647320.032
positive regulation of transportGO:005105020.032
meiotic nuclear divisionGO:000712640.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
cellular protein catabolic processGO:004425740.031
autophagyGO:000691440.031
cellular biosynthetic processGO:00442492860.031
maintenance of locationGO:005123540.030
nuclear transportGO:005116940.030
regulation of meiotic cell cycleGO:005144510.030
lipid storageGO:001991510.029
protein localization to nucleusGO:003450430.029
heterocycle metabolic processGO:00464832900.029
nucleobase containing compound metabolic processGO:00061392740.029
ubiquitin dependent protein catabolic processGO:000651130.029
protein importGO:001703830.029
nucleic acid metabolic processGO:00903042440.029
single organism nuclear importGO:190259330.028
amine metabolic processGO:000930820.028
protein targeting to nucleusGO:004474430.028
regulation of nitrogen compound metabolic processGO:00511712510.028
regulation of establishment of protein localizationGO:007020140.027
cellular response to extracellular stimulusGO:003166820.027
regulation of protein transportGO:005122330.027
positive regulation of cellular component biogenesisGO:004408930.027
protein import into nucleusGO:000660630.027
proteasomal protein catabolic processGO:001049820.027
cellular aromatic compound metabolic processGO:00067252950.027
cellular response to external stimulusGO:007149620.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
cellular response to nutrient levelsGO:003166920.026
nuclear importGO:005117030.026
regulation of protein localization to nucleusGO:190018020.026
single organism metabolic processGO:00447102170.026
aromatic compound biosynthetic processGO:00194382170.025
guanosine containing compound metabolic processGO:190106840.025
organic cyclic compound metabolic processGO:19013603010.025
negative regulation of protein phosphorylationGO:000193340.025
cellular amine metabolic processGO:004410620.025
regulation of nucleocytoplasmic transportGO:004682220.025
mitochondrion organizationGO:000700540.025
regulation of cellular metabolic processGO:00313233200.025
regulation of cytokine productionGO:000181730.025
regulation of neural precursor cell proliferationGO:200017730.025
positive regulation of catabolic processGO:000989640.024
heterocycle biosynthetic processGO:00181302150.024
regulation of protein targetingGO:190353320.024
gene expressionGO:00104672520.024
regulation of cellular amine metabolic processGO:003323800.024
regulation of intracellular protein transportGO:003315730.024
stem cell proliferationGO:007208940.024
generation of neuronsGO:00486993850.024
regulation of metabolic processGO:00192223590.023
organelle fusionGO:004828430.023
nucleobase containing compound biosynthetic processGO:00346542050.023
positive regulation of cell cycleGO:004578730.023
protein acylationGO:004354330.023
macromolecule biosynthetic processGO:00090592270.023
guanosine containing compound catabolic processGO:190106920.023
regulation of autophagyGO:001050630.023
regulation of macromolecule biosynthetic processGO:00105562250.022
cellular response to starvationGO:000926710.022
organic cyclic compound biosynthetic processGO:19013622230.022
gtp catabolic processGO:000618420.022
gtp metabolic processGO:004603940.022
regulation of biosynthetic processGO:00098892500.022
stem cell maintenanceGO:001982740.022
positive regulation of cellular catabolic processGO:003133130.022
regulation of protein complex assemblyGO:004325430.022
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of bindingGO:005109830.022
signal transductionGO:00071654550.021
regulation of protein import into nucleusGO:004230620.021
positive regulation of biological processGO:00485182530.021
establishment of localizationGO:00512342440.021
regulation of cytoplasmic transportGO:190364940.021
meiotic cell cycle processGO:190304630.021
internal peptidyl lysine acetylationGO:001839320.021
cellular macromolecule biosynthetic processGO:00346452240.021
regulation of mrna splicing via spliceosomeGO:004802430.021
regulation of cellular ketone metabolic processGO:001056570.021
extrinsic apoptotic signaling pathwayGO:009719130.021
regulation of macromolecule metabolic processGO:00602553170.021
response to drugGO:004249330.021
cellular amino acid metabolic processGO:000652070.020
peptidyl lysine acetylationGO:001839420.020
regulation of metal ion transportGO:001095940.020
internal protein amino acid acetylationGO:000647520.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
organonitrogen compound metabolic processGO:1901564740.020
regulation of stem cell proliferationGO:007209120.020
positive regulation of stress activated mapk cascadeGO:003287430.020
transcription dna templatedGO:00063511810.020
cognitionGO:005089010.020
rna metabolic processGO:00160702190.019
membrane fusionGO:006102520.019
cellular ketone metabolic processGO:0042180110.019
cell surface receptor signaling pathwayGO:00071663250.019
protein metabolic processGO:00195381830.019
locomotionGO:00400113130.019
modification dependent macromolecule catabolic processGO:004363230.019
organic acid metabolic processGO:0006082310.019
regulation of rna metabolic processGO:00512522240.019
embryo development ending in birth or egg hatchingGO:00097922710.019
negative regulation of cytoplasmic transportGO:190365020.019
cellular protein metabolic processGO:00442671290.019
small molecule metabolic processGO:0044281770.018
regulation of cellular biosynthetic processGO:00313262450.018
carboxylic acid metabolic processGO:0019752220.018
negative regulation of kinase activityGO:003367340.018
endosomal transportGO:001619720.018
regulation of rna biosynthetic processGO:20011412130.018
rna biosynthetic processGO:00327741810.018
phagocytosisGO:000690930.018
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
oxoacid metabolic processGO:0043436310.018
i kappab kinase nf kappab signalingGO:000724940.018
regulation of gene expressionGO:00104682650.018
regulation of protein catabolic processGO:004217610.018
positive regulation of cellular amine metabolic processGO:003324000.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
regulation of primary metabolic processGO:00800903110.018
neuron differentiationGO:00301823530.018
regulation of reproductive processGO:200024140.018
single organism membrane fusionGO:004480120.018
positive regulation of dna metabolic processGO:005105410.017
organic acid catabolic processGO:001605430.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
negative regulation of protein transportGO:005122430.017
atp catabolic processGO:000620040.017
regulation of synapse organizationGO:005080730.017
ribonucleoside monophosphate catabolic processGO:000915840.017
translational initiationGO:000641330.017
response to stressGO:00069502630.017
regulation of mrna processingGO:005068430.017
positive regulation of secretionGO:005104710.017
regulation of transporter activityGO:003240920.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
negative regulation of protein kinase activityGO:000646940.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
meiotic chromosome segregationGO:004513230.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
lipid catabolic processGO:001604240.017
negative regulation of biological processGO:00485193040.017
peptide metabolic processGO:000651810.017
transportGO:00068102200.017
carboxylic acid catabolic processGO:004639530.017
regulation of nucleotide catabolic processGO:003081120.017
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of intracellular transportGO:003238730.016
cytokinesisGO:000091030.016
female sex differentiationGO:004666040.016
regulation of neurotransmitter transportGO:005158810.016
cell cycle g1 s phase transitionGO:004484310.016
cellular component movementGO:00069283350.016
synaptic growth at neuromuscular junctionGO:005112420.016
nucleic acid templated transcriptionGO:00976591810.016
sensory organ developmentGO:00074233930.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
immune system processGO:00023762410.016
response to carbohydrateGO:000974330.016
cellular amide metabolic processGO:004360340.016
regulation of developmental processGO:00507932470.016
compound eye developmentGO:004874920.016
positive regulation of cytokine productionGO:000181920.016
b cell activationGO:004211320.016
regulation of cell activationGO:005086510.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
cellular component disassemblyGO:002241110.016
secondary metabolic processGO:001974830.016
protein secretionGO:000930610.016
fertilizationGO:000956630.016
membrane invaginationGO:001032410.016
regulation of sodium ion transportGO:000202820.015
cell projection morphogenesisGO:00488582440.015
rna localizationGO:000640340.015
g1 s transition of mitotic cell cycleGO:000008210.015
response to external stimulusGO:00096052640.015
response to chemicalGO:00422213200.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
regulation of nucleoside metabolic processGO:000911820.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of signalingGO:00230512350.015
nucleoside monophosphate catabolic processGO:000912540.015
eye developmentGO:00016542770.015
negative regulation of cellular processGO:00485232830.015
production of molecular mediator of immune responseGO:000244020.015
tube morphogenesisGO:00352393490.015
lymphocyte proliferationGO:004665110.015
positive regulation of protein complex assemblyGO:003133420.015
vasculature developmentGO:00019442780.015
regulation of production of molecular mediator of immune responseGO:000270010.015
regulation of gtp catabolic processGO:003312420.015
regulation of protein bindingGO:004339330.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
apoptotic processGO:00069151160.015
neurotransmitter transportGO:000683620.015
positive regulation of immune effector processGO:000269930.014
regulation of protein ubiquitinationGO:003139630.014
cellular component assemblyGO:00226071700.014
primary neural tube formationGO:001402010.014
protein complex disassemblyGO:004324110.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
transcription from rna polymerase ii promoterGO:0006366800.014
leukocyte proliferationGO:007066110.014
positive regulation of translationGO:004572710.014
negative regulation of catabolic processGO:000989530.014
regulation of gtpase activityGO:004308720.014
chordate embryonic developmentGO:00430092710.014
macromolecular complex disassemblyGO:003298410.014
interspecies interaction between organismsGO:004441940.014
regulation of synaptic plasticityGO:004816710.014
chemosensory behaviorGO:000763510.014
single organism localizationGO:19025782250.014
response to monosaccharideGO:003428430.014
centrosome organizationGO:005129710.014
cell projection organizationGO:00300302840.014
rna transportGO:005065820.014
cellular response to oxygen levelsGO:007145310.014
regulation of transcription dna templatedGO:00063552130.014
nuclear exportGO:005116810.014
response to nutrientGO:000758430.014
neuroblast proliferationGO:000740520.014
organelle organizationGO:00069962270.014
positive regulation of gtp catabolic processGO:003312610.014
regulation of response to biotic stimulusGO:000283120.014
protein localization to plasma membraneGO:007265910.014
positive regulation of nucleotide catabolic processGO:003081310.014
mitotic dna damage checkpointGO:004477340.014
mitotic dna integrity checkpointGO:004477440.013
phagocytosis engulfmentGO:000691110.013
regionalizationGO:00030022740.013
macroautophagyGO:001623610.013
cell morphogenesisGO:00009022890.013
cellular component morphogenesisGO:00329893360.013
small molecule catabolic processGO:004428230.013
cell part morphogenesisGO:00329902460.013
embryonic organ developmentGO:00485683810.013
head developmentGO:00603223030.013
cell substrate adhesionGO:003158940.013
erk1 and erk2 cascadeGO:007037140.013
regulation of reactive oxygen species metabolic processGO:200037720.013
regulation of response to stimulusGO:00485832690.013
positive regulation of cell activationGO:005086710.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
peptidyl serine modificationGO:001820920.013
blood vessel developmentGO:00015682460.013
negative regulation of mapk cascadeGO:004340940.013
growthGO:00400071740.013
negative regulation of cytokine productionGO:000181810.013
response to glucoseGO:000974930.013
regulation of erk1 and erk2 cascadeGO:007037240.013
positive regulation of cytoskeleton organizationGO:005149530.013
positive regulation of gtpase activityGO:004354710.013
golgi vesicle transportGO:004819330.013
cellular response to decreased oxygen levelsGO:003629410.013
response to uvGO:000941130.013
nucleic acid transportGO:005065720.013
female gonad developmentGO:000858540.013
negative regulation of intracellular protein transportGO:009031730.013
regulation of alternative mrna splicing via spliceosomeGO:000038110.013
multicellular organismal metabolic processGO:004423620.013
regulation of cell communicationGO:00106462320.013
locomotor rhythmGO:004547530.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
adult behaviorGO:003053420.013
purine nucleoside monophosphate catabolic processGO:000912840.013
double strand break repairGO:000630230.013
blood vessel morphogenesisGO:00485142160.013
regulation of signal transductionGO:00099662250.013
regulation of protein complex disassemblyGO:004324410.013
regulation of cell shapeGO:000836010.013
programmed cell deathGO:00125011190.013
protein polyubiquitinationGO:000020940.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
glucose homeostasisGO:004259310.012
microtubule organizing center organizationGO:003102310.012
exocytosisGO:000688710.012
camera type eye developmentGO:00430102220.012
viral processGO:001603210.012
response to hexoseGO:000974630.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
neurotransmitter secretionGO:000726920.012
positive regulation of chromosome organizationGO:200125210.012
regulation of cellular protein catabolic processGO:190336210.012
positive regulation of jnk cascadeGO:004633030.012
positive regulation of cellular processGO:00485222010.012
adherens junction organizationGO:003433240.012
peptidyl serine phosphorylationGO:001810510.012
regulation of dna replicationGO:000627530.012
regulation of multicellular organismal processGO:00512392770.012
spermatid developmentGO:000728620.012
nucleobase containing compound transportGO:001593120.012
dna templated transcription elongationGO:000635430.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
positive regulation of chromatin modificationGO:190331010.012
protein homooligomerizationGO:005126030.012
mononuclear cell proliferationGO:003294310.012
single organism organelle organizationGO:19025891990.012
central nervous system developmentGO:00074173870.012
cytoplasm organizationGO:000702840.012
positive regulation of secretion by cellGO:190353210.012
heart developmentGO:00075073130.012
cell migrationGO:00164772370.012
cell deathGO:00082191210.012
regulation of calcium ion transportGO:005192420.012
peptide transportGO:001583310.012
regulation of ion transmembrane transporter activityGO:003241220.012
regulation of multicellular organismal developmentGO:20000262230.012
negative regulation of map kinase activityGO:004340720.012
spermatid differentiationGO:004851520.012
regulation of chromosome segregationGO:005198310.012
organism emergence from protective structureGO:007168440.012
antimicrobial humoral responseGO:001973020.012
regulation of synapse assemblyGO:005196330.012
regulation of cell developmentGO:00602841000.012
establishment of rna localizationGO:005123630.012
tube closureGO:006060610.012
single fertilizationGO:000733830.012
macromolecule modificationGO:00434121110.012
negative regulation of protein import into nucleusGO:004230820.011
positive regulation of nucleoside metabolic processGO:004597910.011
mitochondrial transportGO:000683920.011
somatic stem cell maintenanceGO:003501910.011
developmental programmed cell deathGO:001062340.011
cellular component biogenesisGO:00440851780.011
development of primary female sexual characteristicsGO:004654540.011
alcohol biosynthetic processGO:004616520.011
cytoskeleton dependent cytokinesisGO:006164030.011
angiogenesisGO:00015251580.011
tissue remodelingGO:004877140.011
regulation of stem cell differentiationGO:200073640.011
cell matrix adhesionGO:000716040.011
carbohydrate homeostasisGO:003350010.011
regulation of cell differentiationGO:00455951420.011
negative regulation of cellular catabolic processGO:003133030.011
neuron developmentGO:00486662620.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
negative regulation of nuclear divisionGO:005178430.011
homeostatic processGO:00425921420.011
g2 dna damage checkpointGO:003157230.011
positive regulation of cell adhesionGO:004578510.011
lateral inhibitionGO:004633110.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
cellular response to radiationGO:007147840.011
single organism transportGO:00447652060.011
startle responseGO:000196440.011
retina development in camera type eyeGO:00600411460.011
negative regulation of stem cell differentiationGO:200073720.011
negative regulation of protein localization to nucleusGO:190018120.011
regulation of inflammatory responseGO:005072720.011
response to abiotic stimulusGO:00096281220.011
cell agingGO:000756920.011
phosphate containing compound metabolic processGO:00067961080.011
protein heterooligomerizationGO:005129110.011
hemopoiesisGO:00300971830.011
response to corticosteroidGO:003196010.011
anterior posterior pattern specificationGO:00099521520.011
b cell mediated immunityGO:001972430.011
cellular protein modification processGO:00064641000.011
regulation of dna templated transcription elongationGO:003278430.011
regulation of epithelial cell proliferationGO:005067830.011
cellular lipid catabolic processGO:004424230.011
regulation of jak stat cascadeGO:004642530.010
positive regulation of myeloid cell differentiationGO:004563920.010
protein stabilizationGO:005082120.010
brain developmentGO:00074202930.010
somite developmentGO:0061053960.010
xenobiotic metabolic processGO:000680540.010
neuromuscular synaptic transmissionGO:000727420.010
regulation of biological qualityGO:00650082630.010
establishment of synaptic vesicle localizationGO:009748010.010
regulation of dendrite developmentGO:005077330.010
somatic muscle developmentGO:000752540.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
intracellular mrna localizationGO:000829810.010
regulation of transmembrane transporter activityGO:002289820.010
monocarboxylic acid catabolic processGO:007232930.010
fatty acid biosynthetic processGO:000663340.010
lipid oxidationGO:003444010.010
regulation of cellular component organizationGO:0051128860.010
localization of cellGO:00516742440.010
rna modificationGO:000945120.010
positive regulation of erk1 and erk2 cascadeGO:007037420.010
regulation of neurotransmitter secretionGO:004692810.010
meiosis iGO:000712710.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
negative regulation of multi organism processGO:004390130.010
protein dephosphorylationGO:000647030.010
sequestering of calcium ionGO:005120830.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
positive regulation of multi organism processGO:004390230.010
vacuolar transportGO:000703420.010
dorsal ventral pattern formationGO:00099531250.010
digestive system developmentGO:00551232890.010
sequestering of metal ionGO:005123830.010
centrosome cycleGO:000709810.010
positive regulation of ras protein signal transductionGO:004657910.010
cellular respirationGO:004533330.010
regulation of carbohydrate metabolic processGO:000610940.010

pin4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
musculoskeletal system diseaseDOID:1700.022
nervous system diseaseDOID:86300.019
disease of metabolismDOID:001466700.018
immune system diseaseDOID:291400.013
muscular diseaseDOID:008000000.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.011
cardiovascular system diseaseDOID:128700.010
intrinsic cardiomyopathyDOID:006003600.010
cardiomyopathyDOID:005070000.010
heart diseaseDOID:11400.010