Danio rerio

0 known processes

lhx3

LIM homeobox 3

(Aliases: lim3)

lhx3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
diencephalon developmentGO:0021536580.749
regulation of rna metabolic processGO:00512522240.701
regulation of multicellular organismal processGO:00512392770.665
generation of neuronsGO:00486993850.659
brain developmentGO:00074202930.651
ventral spinal cord developmentGO:0021517350.648
gabaergic neuron differentiationGO:009715420.636
regionalizationGO:00030022740.606
regulation of developmental processGO:00507932470.587
aromatic compound biosynthetic processGO:00194382170.578
central nervous system developmentGO:00074173870.551
cell projection morphogenesisGO:00488582440.547
regulation of multicellular organismal developmentGO:20000262230.522
facial nerve developmentGO:002156130.522
regulation of embryonic developmentGO:0045995470.516
sensory organ developmentGO:00074233930.514
specification of symmetryGO:00097992040.503
dorsal ventral pattern formationGO:00099531250.500
neuroblast differentiationGO:001401610.494
neuron differentiationGO:00301823530.470
embryonic organ developmentGO:00485683810.458
neuron fate specificationGO:0048665200.441
eye morphogenesisGO:00485921440.404
spinal cord motor neuron cell fate specificationGO:002152080.397
neuron projection guidanceGO:0097485860.392
cell part morphogenesisGO:00329902460.360
neuron projection extension involved in neuron projection guidanceGO:1902284100.356
forebrain cell migrationGO:002188510.353
cell differentiation in spinal cordGO:0021515400.337
central nervous system neuron differentiationGO:0021953740.333
signal transductionGO:00071654550.333
embryonic organ morphogenesisGO:00485622740.332
cellular nitrogen compound biosynthetic processGO:00442712180.326
regulation of nucleic acid templated transcriptionGO:19035062130.325
nerve developmentGO:0021675450.307
chordate embryonic developmentGO:00430092710.299
leukocyte activationGO:0045321120.291
axonogenesisGO:00074091520.277
regulation of cell differentiationGO:00455951420.275
regulation of cell developmentGO:00602841000.269
regulation of organ growthGO:004662030.258
regulation of anatomical structure morphogenesisGO:00226031300.254
positive regulation of epithelial cell differentiationGO:003085820.247
regulation of cellular biosynthetic processGO:00313262450.247
cellular macromolecule metabolic processGO:00442603910.243
regulation of cellular macromolecule biosynthetic processGO:20001122220.243
rna metabolic processGO:00160702190.242
transcription from rna polymerase ii promoterGO:0006366800.242
cell morphogenesis involved in differentiationGO:00009041950.240
cellular component morphogenesisGO:00329893360.239
cell morphogenesis involved in neuron differentiationGO:00486671630.233
neuron fate commitmentGO:0048663260.231
nucleobase containing compound biosynthetic processGO:00346542050.226
regulation of axonogenesisGO:0050770320.226
response to chemicalGO:00422213200.223
heterocycle biosynthetic processGO:00181302150.217
neuron projection extensionGO:1990138450.215
skeletal system developmentGO:00015011810.210
axon developmentGO:00615641660.209
eye photoreceptor cell differentiationGO:0001754450.207
biosynthetic processGO:00090582940.204
cell projection organizationGO:00300302840.203
inner ear developmentGO:00488391260.201
regulation of transcription dna templatedGO:00063552130.201
cell fate specificationGO:0001708680.197
positive regulation of developmental processGO:0051094500.195
macromolecule biosynthetic processGO:00090592270.193
regulation of biosynthetic processGO:00098892500.192
embryonic skeletal system morphogenesisGO:0048704930.190
fin developmentGO:0033333770.185
skeletal system morphogenesisGO:00487051020.183
neuron projection morphogenesisGO:00488121610.182
spinal cord developmentGO:0021510460.178
agingGO:000756820.178
gene expressionGO:00104672520.177
cell surface receptor signaling pathwayGO:00071663250.177
positive regulation of transcription dna templatedGO:0045893570.176
monoamine transportGO:001584410.173
appendage developmentGO:0048736800.166
nitrogen compound metabolic processGO:00068073190.164
determination of heart left right asymmetryGO:00613711170.164
pancreatic a cell developmentGO:000332220.163
regulation of mechanoreceptor differentiationGO:004563110.162
regulation of axon guidanceGO:190266780.162
response to organic substanceGO:00100331530.159
digestive tract morphogenesisGO:00485462310.157
cellular biosynthetic processGO:00442492860.149
growthGO:00400071740.147
organic cyclic compound metabolic processGO:19013603010.147
digestive system developmentGO:00551232890.146
determination of left right symmetryGO:00073681790.139
cellular macromolecule biosynthetic processGO:00346452240.137
negative regulation of biological processGO:00485193040.134
transcription dna templatedGO:00063511810.134
regulation of biological qualityGO:00650082630.132
neuron projection developmentGO:00311751800.132
embryonic limb morphogenesisGO:003032620.131
regulation of primary metabolic processGO:00800903110.128
embryonic skeletal system developmentGO:0048706970.127
rna biosynthetic processGO:00327741810.127
developmental growthGO:00485891660.127
specification of organ identityGO:001009220.126
positive regulation of neural precursor cell proliferationGO:200017910.126
regulation of axon extensionGO:0030516240.125
axon extensionGO:0048675450.122
regulation of extent of cell growthGO:0061387290.122
chemotaxisGO:00069351040.120
gastrulationGO:00073692080.119
positive regulation of cellular biosynthetic processGO:0031328680.119
developmental growth involved in morphogenesisGO:0060560860.119
positive regulation of embryonic developmentGO:004001930.119
mechanoreceptor differentiationGO:0042490370.118
response to external stimulusGO:00096052640.117
spinal cord motor neuron differentiationGO:0021522260.117
nucleic acid templated transcriptionGO:00976591810.113
response to nicotineGO:003509420.113
regulation of cellular metabolic processGO:00313233200.113
regulation of transcription from rna polymerase ii promoterGO:00063571140.111
regulation of nucleobase containing compound metabolic processGO:00192192500.111
positive regulation of nitrogen compound metabolic processGO:0051173690.110
embryonic skeletal joint morphogenesisGO:006027230.110
bmp signaling pathwayGO:0030509520.110
optic cup morphogenesis involved in camera type eye developmentGO:000207270.109
anatomical structure arrangementGO:004853220.108
pancreas developmentGO:0031016840.108
neuron developmentGO:00486662620.107
nuclear transportGO:005116940.102
regulation of macromolecule biosynthetic processGO:00105562250.102
digestive tract developmentGO:00485652650.102
facial nerve morphogenesisGO:002161010.102
cardiac chamber formationGO:000320740.101
hindbrain developmentGO:0030902910.100
striated muscle tissue developmentGO:00147061100.099
positive regulation of biological processGO:00485182530.097
forebrain neuron developmentGO:002188470.094
regulation of signalingGO:00230512350.092
determination of bilateral symmetryGO:00098552040.090
organic substance biosynthetic processGO:19015762890.089
sensory organ morphogenesisGO:00905962000.088
nephron epithelium morphogenesisGO:007208810.088
heterocycle metabolic processGO:00464832900.088
regulation of multicellular organism growthGO:004001440.088
segmentationGO:0035282970.087
response to endogenous stimulusGO:0009719830.087
response to alkaloidGO:004327920.086
thalamus developmentGO:002179460.085
cellular nitrogen compound metabolic processGO:00346412900.085
ventral spinal cord interneuron fate commitmentGO:006057930.085
regulation of macromolecule metabolic processGO:00602553170.084
forebrain developmentGO:0030900960.082
steroid hormone mediated signaling pathwayGO:004340190.082
negative regulation of sequestering of calcium ionGO:005128340.080
positive regulation of cellular metabolic processGO:0031325940.080
preganglionic parasympathetic nervous system developmentGO:002178360.080
neuron fate determinationGO:004866420.080
heart developmentGO:00075073130.079
urogenital system developmentGO:0001655970.079
axon guidanceGO:0007411860.077
retina development in camera type eyeGO:00600411460.076
behaviorGO:0007610740.076
cellular component movementGO:00069283350.076
circulatory system processGO:0003013870.075
inner ear morphogenesisGO:0042472630.074
immune system developmentGO:00025201910.074
synaptic target recognitionGO:000803910.074
adenohypophysis developmentGO:0021984150.074
regulation of behaviorGO:0050795240.072
neural retina developmentGO:0003407490.072
regulation of inner ear receptor cell differentiationGO:200098010.071
regulation of neuron differentiationGO:0045664560.070
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.070
heart loopingGO:0001947940.069
regulation of cellular component organizationGO:0051128860.069
cell cell signaling involved in cell fate commitmentGO:0045168120.069
otic vesicle developmentGO:0071599420.069
auditory receptor cell fate commitmentGO:000991240.069
positive regulation of cellular processGO:00485222010.068
ear developmentGO:00435831270.068
muscle organ developmentGO:00075171010.067
positive regulation of macromolecule metabolic processGO:0010604930.067
endocardium formationGO:006021410.066
columnar cuboidal epithelial cell differentiationGO:0002065380.066
cell proliferationGO:0008283800.066
nucleic acid metabolic processGO:00903042440.066
regulation of axon extension involved in axon guidanceGO:004884160.065
camera type eye developmentGO:00430102220.063
phasic smooth muscle contractionGO:001482110.063
negative regulation of multicellular organismal processGO:0051241690.063
muscle cell fate determinationGO:000752110.062
regulation of synaptic plasticityGO:004816710.062
cognitionGO:005089010.062
morphogenesis of an epitheliumGO:00020093330.062
regulation of endodermal cell fate specificationGO:0042663150.061
eye developmentGO:00016542770.061
axial mesodermal cell fate specificationGO:004832730.060
cellular aromatic compound metabolic processGO:00067252950.060
nephron morphogenesisGO:007202820.059
convergent extension involved in organogenesisGO:0060029100.059
cardiogenic plate morphogenesisGO:000314210.058
transportGO:00068102200.057
cell fate commitment involved in formation of primary germ layerGO:0060795260.056
positive regulation of rna metabolic processGO:0051254590.056
neuroblast fate commitmentGO:001401710.056
cell morphogenesisGO:00009022890.055
regulation of rna biosynthetic processGO:20011412130.054
ear morphogenesisGO:0042471640.052
notochord developmentGO:0030903540.051
dna methylation or demethylationGO:004472880.051
negative regulation of mesodermal cell fate specificationGO:004266230.050
midbrain hindbrain boundary developmentGO:0030917230.050
cranial nerve developmentGO:0021545420.050
embryonic camera type eye formationGO:0060900100.049
cellular response to organic substanceGO:00713101050.049
response to hormoneGO:0009725480.049
mesenchymal cell developmentGO:0014031780.049
pharyngeal muscle developmentGO:004328240.048
positive regulation of macromolecule biosynthetic processGO:0010557590.047
regulation of gastrulationGO:0010470240.047
cellular response to endogenous stimulusGO:0071495680.047
enzyme linked receptor protein signaling pathwayGO:00071671060.047
tube morphogenesisGO:00352393490.047
establishment of localizationGO:00512342440.047
regulation of response to stimulusGO:00485832690.046
regulation of nitrogen compound metabolic processGO:00511712510.046
axon extension involved in axon guidanceGO:0048846100.046
locomotionGO:00400113130.046
cellular component biogenesisGO:00440851780.046
rostrocaudal neural tube patterningGO:0021903290.045
photoreceptor cell fate commitmentGO:004655210.045
floor plate morphogenesisGO:0033505120.045
nephron tubule morphogenesisGO:007207810.045
ventral spinal cord interneuron differentiationGO:0021514120.045
liver developmentGO:0001889960.045
auditory receptor cell fate determinationGO:004266820.044
hepaticobiliary system developmentGO:0061008980.044
taxisGO:00423301090.044
determination of dorsal ventral asymmetryGO:0048262340.044
nucleobase containing compound metabolic processGO:00061392740.044
cellular response to chemical stimulusGO:00708871570.044
glial cell migrationGO:000834730.043
embryonic skeletal joint developmentGO:007249830.042
neurological system processGO:0050877620.042
endocrine system developmentGO:0035270650.042
tissue remodelingGO:004877140.042
positive regulation of nucleic acid templated transcriptionGO:1903508570.041
cell growthGO:0016049570.041
muscle tissue developmentGO:00605371100.041
cell fate commitmentGO:0045165990.041
wnt signaling pathwayGO:0016055800.041
response to oxygen containing compoundGO:1901700550.040
dna methylationGO:000630680.040
organic cyclic compound biosynthetic processGO:19013622230.040
heart processGO:0003015710.039
regulation of neural retina developmentGO:006107420.039
ventral spinal cord interneuron specificationGO:002152130.039
appendage morphogenesisGO:0035107560.038
hemopoiesisGO:00300971830.038
gland developmentGO:00487321430.038
heart formationGO:0060914130.038
gastrulation with mouth forming secondGO:0001702440.038
head developmentGO:00603223030.038
regulation of neuron migrationGO:200122220.038
fin regenerationGO:0031101510.038
anterior lateral line nerve developmentGO:004890940.037
circadian sleep wake cycleGO:004274520.037
otolith developmentGO:0048840320.037
vasculature developmentGO:00019442780.035
morphogenesis of a branching structureGO:0001763210.035
mesenchyme developmentGO:00604851270.034
positive regulation of nucleobase containing compound metabolic processGO:0045935690.034
multicellular organism growthGO:003526440.034
regulation of photoreceptor cell differentiationGO:004653220.033
neural crest cell differentiationGO:0014033720.033
neural plate pattern specificationGO:0060896120.033
regulation of bmp signaling pathwayGO:0030510390.033
positive regulation of biosynthetic processGO:0009891680.033
immune system processGO:00023762410.033
angiogenesisGO:00015251580.033
cell proliferation involved in heart morphogenesisGO:006132320.032
negative regulation of signal transductionGO:0009968940.032
spinal cord oligodendrocyte cell fate specificationGO:002153020.032
vestibular receptor cell developmentGO:006011830.032
central nervous system segmentationGO:003528360.032
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.032
regulation of nervous system developmentGO:0051960900.032
positive regulation of rna biosynthetic processGO:1902680570.032
embryonic heart tube morphogenesisGO:00031431080.031
regulation of circadian sleep wake cycleGO:004274910.031
positive regulation of cell developmentGO:0010720250.031
negative regulation of axon guidanceGO:190266810.031
regulation of metabolic processGO:00192223590.031
dopamine metabolic processGO:004241720.030
regulation of cell communicationGO:00106462320.030
ectoderm developmentGO:000739890.030
regulation of cell sizeGO:0008361290.030
positive regulation of multicellular organismal processGO:0051240520.030
tissue regenerationGO:0042246740.030
cell migration in hindbrainGO:002153570.029
single organism localizationGO:19025782250.029
embryonic retina morphogenesis in camera type eyeGO:0060059220.029
regulation of cell shapeGO:000836010.029
circadian sleep wake cycle processGO:002241020.029
bone remodelingGO:004684920.029
regulation of retina development in camera type eyeGO:190286620.029
positive regulation of transportGO:005105020.029
regulation of cell fate commitmentGO:0010453220.029
neuroblast proliferationGO:000740520.028
enteroendocrine cell differentiationGO:003588390.028
regulation of neurogenesisGO:0050767870.028
cell cell signalingGO:0007267520.028
extraocular skeletal muscle developmentGO:000207430.028
cardiac atrium morphogenesisGO:000320920.028
glial cell fate determinationGO:000740310.028
negative regulation of behaviorGO:004852160.028
epithelial tube morphogenesisGO:00605621480.028
connective tissue developmentGO:0061448990.028
mesodermal cell fate specificationGO:0007501120.027
metencephalon developmentGO:0022037270.027
hematopoietic stem cell differentiationGO:0060218200.026
lateral line developmentGO:0048882660.026
regulation of organ morphogenesisGO:2000027350.026
response to lipidGO:0033993600.026
negative regulation of stem cell differentiationGO:200073720.026
regulation of cell morphogenesis involved in differentiationGO:0010769380.026
intracellular estrogen receptor signaling pathwayGO:003052030.026
myeloid cell differentiationGO:0030099860.026
sensory perception of chemical stimulusGO:000760630.025
establishment of localization in cellGO:0051649770.025
blood vessel morphogenesisGO:00485142160.025
negative regulation of cell deathGO:0060548600.025
neural tube developmentGO:0021915620.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
response to alcoholGO:0097305140.024
negative regulation of neurogenesisGO:0050768200.024
negative regulation of nervous system developmentGO:0051961220.024
cellular response to hormone stimulusGO:0032870390.024
positive regulation of metabolic processGO:00098931080.024
positive regulation of cell fate commitmentGO:001045510.024
muscle structure developmentGO:00610611960.023
parasympathetic nervous system developmentGO:004848660.023
ectodermal placode formationGO:0060788260.023
regulation of gene expressionGO:00104682650.023
developmental programmed cell deathGO:001062340.023
hormone transportGO:000991420.023
endocardium morphogenesisGO:000316040.023
single organism behaviorGO:0044708240.022
muscle cell developmentGO:00550011150.022
cellular component assemblyGO:00226071700.022
morphogenesis of embryonic epitheliumGO:0016331300.022
cartilage developmentGO:0051216960.022
mechanosensory behaviorGO:000763820.022
fin morphogenesisGO:0033334530.022
brain segmentationGO:003528460.022
hormone secretionGO:004687920.022
synapse organizationGO:0050808210.021
regulation of blood pressureGO:000821710.021
renal tubule morphogenesisGO:006133310.021
retinal cone cell differentiationGO:0042670120.021
reproductive processGO:0022414400.021
cell motilityGO:00488702440.021
cardiocyte differentiationGO:0035051440.021
post embryonic morphogenesisGO:000988640.021
circadian sleep wake cycle sleepGO:005080210.021
striated muscle cell proliferationGO:001485570.021
epithelial cell differentiationGO:00308551160.020
hormone mediated signaling pathwayGO:000975590.020
midbrain developmentGO:0030901280.020
protein importGO:001703830.020
localization of cellGO:00516742440.020
convergent extensionGO:00600261180.020
single organism metabolic processGO:00447102170.020
negative regulation of cell developmentGO:0010721260.019
oligodendrocyte cell fate specificationGO:002177840.019
positive regulation of neurogenesisGO:0050769240.019
erythrocyte developmentGO:0048821240.019
negative regulation of developmental processGO:0051093650.019
pigmentationGO:0043473850.019
hypochord developmentGO:005501630.019
regulation of blood circulationGO:1903522320.018
trigeminal nerve developmentGO:002155930.018
retina morphogenesis in camera type eyeGO:0060042790.018
camera type eye morphogenesisGO:00485931080.018
stem cell developmentGO:0048864820.018
regulation of dna methylationGO:004403050.018
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.018
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225450.018
embryonic camera type eye morphogenesisGO:0048596190.018
peripheral nervous system neuron differentiationGO:0048934280.018
neurotransmitter transportGO:000683620.018
b cell activationGO:004211320.018
organ formationGO:0048645170.018
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.018
positive regulation of cell cycleGO:004578730.018
neural crest cell developmentGO:0014032620.018
kidney developmentGO:0001822920.018
autonomic nervous system developmentGO:0048483190.017
regulation of chemotaxisGO:0050920180.017
regulation of neuron projection developmentGO:0010975400.017
response to ethanolGO:004547160.017
ectodermal placode morphogenesisGO:0071697320.017
regenerationGO:0031099910.017
developmental cell growthGO:0048588520.017
peripheral nervous system developmentGO:0007422550.017
lateral inhibitionGO:004633110.017
negative regulation of neuron differentiationGO:0045665100.017
regulation of canonical wnt signaling pathwayGO:0060828340.017
post embryonic organ morphogenesisGO:004856310.017
closure of optic fissureGO:006138660.017
cellular response to organic cyclic compoundGO:0071407380.016
aorta morphogenesisGO:003590930.016
embryonic pattern specificationGO:0009880440.016
cardiac atrium developmentGO:000323040.016
organelle localizationGO:0051640490.016
anterior head developmentGO:009706520.016
positive regulation of striated muscle tissue developmentGO:004584410.016
eye photoreceptor cell developmentGO:0042462300.016
positive regulation of notch signaling pathwayGO:004574730.015
regulation of growthGO:0040008420.015
mesodermal cell fate commitmentGO:0001710140.015
canonical wnt signaling pathwayGO:0060070480.015
cellular response to fibroblast growth factor stimulusGO:0044344220.015
renal system developmentGO:0072001940.015
cell migrationGO:00164772370.015
dendrite guidanceGO:007098300.015
anterior posterior pattern specificationGO:00099521520.015
cardiac cell fate commitmentGO:006091110.015
negative regulation of cellular processGO:00485232830.015
cartilage morphogenesisGO:0060536130.015
regulation of cell proliferation involved in heart morphogenesisGO:200013620.014
regulation of synapse organizationGO:005080730.014
mesoderm developmentGO:0007498880.014
striated muscle cell differentiationGO:00511461290.014
neural plate developmentGO:0001840100.014
heart morphogenesisGO:00030071560.014
pectoral fin developmentGO:0033339500.014
regulation of anterior head developmentGO:200074220.014
lymphocyte activationGO:0046649100.014
developmental inductionGO:0031128100.014
endocrine pancreas developmentGO:0031018270.014
glial cell fate specificationGO:002178040.014
regulation of lipid catabolic processGO:005099420.014
proximal distal pattern formationGO:000995410.013
cell migration involved in gastrulationGO:0042074790.013
muscle cell differentiationGO:00426921390.013
negative regulation of gene expressionGO:0010629650.013
response to mechanical stimulusGO:0009612240.013
regulation of cell fate specificationGO:0042659200.013
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.013
protein secretionGO:000930610.013
regulation of cell activationGO:005086510.013
leukocyte differentiationGO:0002521250.013
positive regulation of nervous system developmentGO:0051962250.013
glandular epithelial cell differentiationGO:000206790.013
cell activationGO:0001775160.013
endocrine processGO:005088620.012
dorsal ventral axis specificationGO:0009950140.012
retinal ganglion cell axon guidanceGO:0031290350.012
regulation of establishment of protein localizationGO:007020140.012
response to organic cyclic compoundGO:0014070510.012
hard palate developmentGO:006002240.012
type b pancreatic cell developmentGO:000332340.012
regulation of neural precursor cell proliferationGO:200017730.012
regulation of protein transportGO:005122330.012
inner ear receptor cell developmentGO:0060119200.012
optic nerve developmentGO:0021554150.012
pancreatic a cell differentiationGO:000331060.012
response to oxygen levelsGO:0070482250.012
wound healingGO:0042060900.012
ectodermal placode developmentGO:0071696370.012
septum transversum developmentGO:000334340.012
determination of dorsal identityGO:0048263130.012
negative regulation of apoptotic processGO:0043066550.012
regulation of epithelial cell proliferationGO:005067830.012
adult behaviorGO:003053420.012
small molecule metabolic processGO:0044281770.012
embryonic heart tube developmentGO:00350501330.012
mesenchymal cell differentiationGO:0048762870.012
regulation of mesodermal cell fate specificationGO:004266190.012
negative regulation of macromolecule metabolic processGO:0010605760.012
neuron deathGO:0070997210.012
morphogenesis of an epithelial sheetGO:0002011490.012
neuroepithelial cell differentiationGO:0060563260.012
regulation of cellular component sizeGO:0032535300.012
kupffer s vesicle developmentGO:0070121500.012
inner ear receptor cell differentiationGO:0060113290.012
invagination involved in gastrulation with mouth forming secondGO:005510910.011
negative regulation of response to stimulusGO:00485851040.011
positive regulation of cell proliferationGO:0008284150.011

lhx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.043
bone diseaseDOID:008000100.043
bone development diseaseDOID:008000600.043
disease of anatomical entityDOID:700.043
musculoskeletal system diseaseDOID:1700.043
nervous system diseaseDOID:86300.020
sensory system diseaseDOID:005015500.020
osteochondrodysplasiaDOID:225600.015