Danio rerio

0 known processes

dock2

dedicator of cyto-kinesis 2 and dedicator of cytokinesis 2

(Aliases: cb1005)

dock2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular extravasationGO:000269310.290
adherens junction organizationGO:003433240.074
larval developmentGO:000216420.067
regulation of cell activationGO:005086510.059
agingGO:000756820.047
superoxide metabolic processGO:000680120.042
regulation of multicellular organism growthGO:004001440.041
phagocytosisGO:000690930.040
positive regulation of catabolic processGO:000989640.039
multicellular organism growthGO:003526440.039
positive regulation of cytokine productionGO:000181920.039
response to chemicalGO:00422213200.036
positive regulation of cell adhesionGO:004578510.032
locomotionGO:00400113130.032
regulation of inflammatory responseGO:005072720.032
synaptic transmission cholinergicGO:000727140.031
proteolysis involved in cellular protein catabolic processGO:005160330.031
cell matrix adhesionGO:000716040.031
regulation of establishment of protein localizationGO:007020140.031
cellular nitrogen compound metabolic processGO:00346412900.030
tube morphogenesisGO:00352393490.030
regulation of primary metabolic processGO:00800903110.030
positive regulation of transportGO:005105020.030
positive regulation of cellular catabolic processGO:003133130.028
response to stressGO:00069502630.028
cellular nitrogen compound biosynthetic processGO:00442712180.027
negative regulation of protein phosphorylationGO:000193340.027
dicarboxylic acid transportGO:000683510.027
lamellipodium organizationGO:009758110.027
regulation of protein catabolic processGO:004217610.027
cellular component movementGO:00069283350.026
cellular protein catabolic processGO:004425740.026
localization of cellGO:00516742440.025
response to amino acidGO:004320020.025
positive regulation of cell activationGO:005086710.025
cellular amino acid metabolic processGO:000652070.025
regulation of cytokine productionGO:000181730.025
regulation of cellular biosynthetic processGO:00313262450.025
positive regulation of cellular component biogenesisGO:004408930.024
neuron neuron synaptic transmissionGO:000727010.024
lipid storageGO:001991510.024
positive regulation of inflammatory responseGO:005072910.024
cell motilityGO:00488702440.024
response to alkaloidGO:004327920.024
organic acid metabolic processGO:0006082310.023
regulation of circadian rhythmGO:004275240.023
biosynthetic processGO:00090582940.023
cell migrationGO:00164772370.023
tissue remodelingGO:004877140.023
regulation of synaptic plasticityGO:004816710.023
smooth muscle contractionGO:000693920.022
nucleobase containing compound biosynthetic processGO:00346542050.022
regulation of circadian sleep wake cycle sleepGO:004518710.022
nitrogen compound metabolic processGO:00068073190.022
embryonic organ developmentGO:00485683810.022
regulation of nitrogen compound metabolic processGO:00511712510.022
regulation of multicellular organismal processGO:00512392770.022
regulation of macromolecule metabolic processGO:00602553170.022
cellular component morphogenesisGO:00329893360.021
autophagyGO:000691440.021
vasculature developmentGO:00019442780.021
regulation of protein complex assemblyGO:004325430.021
macromolecule biosynthetic processGO:00090592270.021
oxoacid metabolic processGO:0043436310.021
maintenance of locationGO:005123540.021
protein acetylationGO:000647320.021
carboxylic acid metabolic processGO:0019752220.021
cellular macromolecule metabolic processGO:00442603910.021
cell substrate adhesionGO:003158940.020
heterocycle biosynthetic processGO:00181302150.020
regulation of metal ion transportGO:001095940.020
positive regulation of secretion by cellGO:190353210.020
single organism metabolic processGO:00447102170.020
regulation of cell substrate adhesionGO:001081010.020
regulation of cell shapeGO:000836010.020
establishment of protein localization to organelleGO:007259440.020
astrocyte differentiationGO:004870810.020
organic substance biosynthetic processGO:19015762890.020
signal transductionGO:00071654550.020
regulation of reproductive processGO:200024140.020
protein localization to plasma membraneGO:007265910.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
cellular biosynthetic processGO:00442492860.020
gene expressionGO:00104672520.019
amine metabolic processGO:000930820.019
positive regulation of biological processGO:00485182530.019
blood vessel morphogenesisGO:00485142160.019
positive regulation of secretionGO:005104710.019
rna metabolic processGO:00160702190.019
cellular component disassemblyGO:002241110.019
regulation of cellular amine metabolic processGO:003323800.019
regulation of muscle contractionGO:000693730.019
modification dependent macromolecule catabolic processGO:004363230.019
guanosine containing compound metabolic processGO:190106840.019
regulation of biosynthetic processGO:00098892500.018
nucleic acid templated transcriptionGO:00976591810.018
nuclear transportGO:005116940.018
neurotransmitter transportGO:000683620.018
response to carbohydrateGO:000974330.018
neuron developmentGO:00486662620.018
organonitrogen compound metabolic processGO:1901564740.018
oxidoreduction coenzyme metabolic processGO:000673310.018
heart developmentGO:00075073130.018
gtp catabolic processGO:000618420.018
regulation of metabolic processGO:00192223590.018
organic cyclic compound biosynthetic processGO:19013622230.018
epithelial tube morphogenesisGO:00605621480.018
sleepGO:003043110.018
muscle organ developmentGO:00075171010.018
guanosine containing compound catabolic processGO:190106920.018
regulation of neurotransmitter secretionGO:004692810.018
immune system processGO:00023762410.017
regulation of cellular amino acid metabolic processGO:000652100.017
transcription dna templatedGO:00063511810.017
mitochondrion organizationGO:000700540.017
blood circulationGO:0008015870.017
ubiquitin dependent protein catabolic processGO:000651130.017
regulation of rna biosynthetic processGO:20011412130.017
response to external stimulusGO:00096052640.017
circadian sleep wake cycleGO:004274520.017
digestive tract morphogenesisGO:00485462310.017
embryonic heart tube developmentGO:00350501330.017
central nervous system developmentGO:00074173870.017
multicellular organismal metabolic processGO:004423620.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
rna biosynthetic processGO:00327741810.017
regulation of rna metabolic processGO:00512522240.017
camera type eye developmentGO:00430102220.017
response to organic substanceGO:00100331530.017
protein metabolic processGO:00195381830.017
regulation of response to stimulusGO:00485832690.017
response to drugGO:004249330.016
cellular aromatic compound metabolic processGO:00067252950.016
positive regulation of cell cycleGO:004578730.016
regulation of gene expressionGO:00104682650.016
stem cell proliferationGO:007208940.016
establishment of protein localization to plasma membraneGO:009000210.016
modification dependent protein catabolic processGO:001994130.016
small molecule metabolic processGO:0044281770.016
amino acid transportGO:000686520.016
cellular response to nutrient levelsGO:003166920.016
cellular protein metabolic processGO:00442671290.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of nucleotide catabolic processGO:003081120.016
protein import into nucleusGO:000660630.016
internal protein amino acid acetylationGO:000647520.016
protein secretionGO:000930610.016
regulation of cellular ketone metabolic processGO:001056570.016
angiogenesisGO:00015251580.016
regulation of multicellular organismal developmentGO:20000262230.016
regulation of apoptotic processGO:0042981980.016
monoamine transportGO:001584410.016
heterocycle metabolic processGO:00464832900.016
protein importGO:001703830.016
nucleobase containing compound metabolic processGO:00061392740.016
positive regulation of gtp catabolic processGO:003312610.016
multicellular organismal macromolecule metabolic processGO:004425920.016
neurotransmitter secretionGO:000726920.016
regulation of circadian sleep wake cycleGO:004274910.016
cell part morphogenesisGO:00329902460.015
regulation of blood vessel sizeGO:005088020.015
rna localizationGO:000640340.015
muscle tissue developmentGO:00605371100.015
organic cyclic compound metabolic processGO:19013603010.015
positive regulation of protein kinase b signalingGO:005189710.015
proteasomal protein catabolic processGO:001049820.015
regulation of erk1 and erk2 cascadeGO:007037240.015
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.015
cellular ketone metabolic processGO:0042180110.015
single organism nuclear importGO:190259330.015
regulation of macromolecule biosynthetic processGO:00105562250.015
cell morphogenesisGO:00009022890.015
blood vessel developmentGO:00015682460.015
organelle fusionGO:004828430.015
intracellular mrna localizationGO:000829810.015
protein acylationGO:004354330.015
regulation of neurotransmitter transportGO:005158810.015
cellular modified amino acid metabolic processGO:000657530.015
neuron differentiationGO:00301823530.015
cell surface receptor signaling pathwayGO:00071663250.015
positive regulation of nucleotide catabolic processGO:003081310.015
stem cell maintenanceGO:001982740.015
regulation of cellular metabolic processGO:00313233200.015
cognitionGO:005089010.015
regulation of rho protein signal transductionGO:003502320.015
cell projection organizationGO:00300302840.015
single organism membrane fusionGO:004480120.015
positive regulation of protein complex assemblyGO:003133420.015
aromatic compound biosynthetic processGO:00194382170.014
meiotic cell cycle processGO:190304630.014
retina development in camera type eyeGO:00600411460.014
response to nutrientGO:000758430.014
sensory organ morphogenesisGO:00905962000.014
cellular amine metabolic processGO:004410620.014
regulation of cellular extravasationGO:000269110.014
exocytosisGO:000688710.014
multicellular organismal response to stressGO:003355520.014
system processGO:00030081850.014
regulation of programmed cell deathGO:00430671010.014
generation of neuronsGO:00486993850.014
regulation of protein transportGO:005122330.014
gtp metabolic processGO:004603940.014
positive regulation of map kinase activityGO:004340630.014
regulation of mrna processingGO:005068430.014
regulation of wound healingGO:006104120.014
regulation of response to external stimulusGO:0032101310.014
synaptic vesicle transportGO:004848910.014
regulation of purine nucleotide catabolic processGO:003312120.014
response to amineGO:001407510.014
actin filament polymerizationGO:003004120.014
cellular response to extracellular stimulusGO:003166820.014
negative regulation of cellular processGO:00485232830.014
collagen metabolic processGO:003296320.014
cellular response to chemical stimulusGO:00708871570.014
cellular response to external stimulusGO:007149620.014
somatic muscle developmentGO:000752540.014
cellular macromolecule biosynthetic processGO:00346452240.014
cellular carbohydrate metabolic processGO:004426240.014
response to amphetamineGO:000197510.014
peptidyl lysine acetylationGO:001839420.014
regulation of mrna splicing via spliceosomeGO:004802430.014
regulation of cytoplasmic transportGO:190364940.014
leukocyte mediated cytotoxicityGO:000190910.014
chemotaxisGO:00069351040.014
muscle structure developmentGO:00610611960.013
regulation of blood pressureGO:000821710.013
lamellipodium assemblyGO:003003210.013
positive regulation of cellular amine metabolic processGO:003324000.013
positive regulation of camp biosynthetic processGO:003081920.013
interspecies interaction between organismsGO:004441940.013
cellular amide metabolic processGO:004360340.013
actin polymerization or depolymerizationGO:000815420.013
regulation of gtpase activityGO:004308720.013
cellular extravasationGO:004512310.013
i kappab kinase nf kappab signalingGO:000724940.013
response to woundingGO:00096111160.013
meiotic nuclear divisionGO:000712640.013
chemosensory behaviorGO:000763510.013
cell projection morphogenesisGO:00488582440.013
cellular protein modification processGO:00064641000.013
negative regulation of catabolic processGO:000989530.013
regulation of nucleoside metabolic processGO:000911820.013
ameboidal type cell migrationGO:00016671430.013
taxisGO:00423301090.013
regulation of tube sizeGO:003515020.013
regulation of bindingGO:005109830.013
regulation of stem cell differentiationGO:200073640.013
synaptic vesicle localizationGO:009747910.013
b cell activationGO:004211320.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
morphogenesis of an epitheliumGO:00020093330.013
membrane fusionGO:006102520.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
mononuclear cell proliferationGO:003294310.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of signalingGO:00230512350.013
protein complex disassemblyGO:004324110.013
neutrophil mediated immunityGO:000244610.013
macromolecular complex disassemblyGO:003298410.013
positive regulation of nucleoside metabolic processGO:004597910.012
nucleocytoplasmic transportGO:000691340.012
response to monosaccharideGO:003428430.012
membrane hyperpolarizationGO:006008110.012
regulation of biological qualityGO:00650082630.012
regulation of transcription dna templatedGO:00063552130.012
cytokinesisGO:000091030.012
negative regulation of defense responseGO:003134820.012
circadian sleep wake cycle sleepGO:005080210.012
regulation of stem cell proliferationGO:007209120.012
negative regulation of mapk cascadeGO:004340940.012
neuroblast proliferationGO:000740520.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
cell substrate junction assemblyGO:000704420.012
gastrulationGO:00073692080.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
regulation of developmental processGO:00507932470.012
reactive oxygen species biosynthetic processGO:190340910.012
lymph vessel morphogenesisGO:0036303250.012
positive regulation of camp metabolic processGO:003081620.012
regulation of protein polymerizationGO:003227120.012
protein polymerizationGO:005125840.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
regulation of cell motilityGO:2000145460.012
leukocyte proliferationGO:007066110.012
response to hydrogen peroxideGO:004254230.012
lymphocyte proliferationGO:004665110.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of cell projection assemblyGO:006049140.012
digestive system developmentGO:00551232890.012
circulatory system processGO:0003013870.012
striated muscle tissue developmentGO:00147061100.012
regulation of locomotionGO:0040012550.012
regulation of protein localization to plasma membraneGO:190307610.012
eye developmentGO:00016542770.012
eye morphogenesisGO:00485921440.011
internal peptidyl lysine acetylationGO:001839320.011
chordate embryonic developmentGO:00430092710.011
regulation of localizationGO:00328791040.011
response to hexoseGO:000974630.011
hormone secretionGO:004687920.011
nuclear importGO:005117030.011
phagocytosis engulfmentGO:000691110.011
regulation of signal transductionGO:00099662250.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
purine nucleoside monophosphate catabolic processGO:000912840.011
cellular component biogenesisGO:00440851780.011
negative regulation of kinase activityGO:003367340.011
response to vitaminGO:003327330.011
cellular aldehyde metabolic processGO:000608140.011
carbohydrate derivative biosynthetic processGO:1901137430.011
transportGO:00068102200.011
single organism organelle organizationGO:19025891990.011
negative regulation of protein kinase b signalingGO:005189820.011
adherens junction assemblyGO:003433310.011
startle responseGO:000196440.011
regulation of nucleobase containing compound metabolic processGO:00192192500.011
immune system developmentGO:00025201910.011
ion transportGO:00068111140.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
negative regulation of synapse assemblyGO:005196420.011
regulation of transporter activityGO:003240920.011
fatty acid transportGO:001590810.011
ribonucleoside monophosphate catabolic processGO:000915840.011
regulation of intracellular protein transportGO:003315730.011
inositol lipid mediated signalingGO:004801720.011
medulla oblongata developmentGO:002155040.011
endosomal transportGO:001619720.011
cellular response to starvationGO:000926710.011
response to endogenous stimulusGO:0009719830.011
positive regulation of protein polymerizationGO:003227320.011
regulation of alternative mrna splicing via spliceosomeGO:000038110.011
homeostatic processGO:00425921420.011
activation of mapk activityGO:000018730.011
regulation of calcium ion transportGO:005192420.011
positive regulation of dna metabolic processGO:005105410.011
regulation of dendrite developmentGO:005077330.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.010
heart processGO:0003015710.010
sequestering of calcium ionGO:005120830.010
cell cycle g1 s phase transitionGO:004484310.010
organelle assemblyGO:00709251100.010
reactive oxygen species metabolic processGO:007259360.010
erk1 and erk2 cascadeGO:007037140.010
lymphangiogenesisGO:0001946250.010
regulation of reactive oxygen species metabolic processGO:200037720.010
regulation of cell developmentGO:00602841000.010
synaptic growth at neuromuscular junctionGO:005112420.010
striated muscle cell developmentGO:00550021080.010
epidermal cell fate specificationGO:000995740.010
bone remodelingGO:004684920.010
calcium ion transport into cytosolGO:006040230.010
macroautophagyGO:001623610.010
muscle cell developmentGO:00550011150.010
embryo development ending in birth or egg hatchingGO:00097922710.010
homeostasis of number of cells within a tissueGO:004887340.010
nucleic acid transportGO:005065720.010

dock2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
disease of metabolismDOID:001466700.022
immune system diseaseDOID:291400.015
inherited metabolic disorderDOID:65500.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
nervous system diseaseDOID:86300.011