IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

(Aliases: si:dkeyp-86a5.1,si:dkey-97c7.1)

Ensembl: ENSDARG00000021590
Entrez: 564112
ZFIN: ZDB-GENE-050810-4
UniProtKB: Q5VSD9

Process Predictions
Disease Predictions

magi2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rna biosynthetic process	GO:0032774	181	0.140
nucleobase containing compound biosynthetic process	GO:0034654	205	0.131
organic substance biosynthetic process	GO:1901576	289	0.116
regulation of rna biosynthetic process	GO:2001141	213	0.097
eye development	GO:0001654	277	0.080
rna metabolic process	GO:0016070	219	0.077
positive regulation of cellular process	GO:0048522	201	0.076	Human Rat
organic cyclic compound biosynthetic process	GO:1901362	223	0.076
transcription dna templated	GO:0006351	181	0.069
regeneration	GO:0031099	91	0.067
cell surface receptor signaling pathway	GO:0007166	325	0.066	Rat
organic cyclic compound metabolic process	GO:1901360	301	0.066
nucleic acid metabolic process	GO:0090304	244	0.062
regulation of nucleic acid templated transcription	GO:1903506	213	0.062
generation of neurons	GO:0048699	385	0.055	Rat
macromolecule biosynthetic process	GO:0009059	227	0.055
nucleobase containing compound metabolic process	GO:0006139	274	0.053
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.048
regulation of nitrogen compound metabolic process	GO:0051171	251	0.042
sensory organ development	GO:0007423	393	0.042
heterocycle metabolic process	GO:0046483	290	0.042
regulation of rna metabolic process	GO:0051252	224	0.041
regulation of signal transduction	GO:0009966	225	0.041	Human
positive regulation of catabolic process	GO:0009896	4	0.040
negative regulation of neuron projection regeneration	GO:0070571	4	0.040
cellular macromolecule metabolic process	GO:0044260	391	0.039	Human
cellular macromolecule biosynthetic process	GO:0034645	224	0.038
heterocycle biosynthetic process	GO:0018130	215	0.038
response to wounding	GO:0009611	116	0.036
cellular biosynthetic process	GO:0044249	286	0.035
aromatic compound biosynthetic process	GO:0019438	217	0.034
larval development	GO:0002164	2	0.033
camera type eye development	GO:0043010	222	0.033
cell migration	GO:0016477	237	0.033	Rat
gene expression	GO:0010467	252	0.032
optic placode formation involved in camera type eye formation	GO:0046619	3	0.031
regulation of cellular biosynthetic process	GO:0031326	245	0.031
regulation of macromolecule metabolic process	GO:0060255	317	0.030	Human
hepatocyte proliferation	GO:0072574	2	0.029
cellular nitrogen compound metabolic process	GO:0034641	290	0.027
skeletal system development	GO:0001501	181	0.027
cellular component movement	GO:0006928	335	0.027	Rat
nucleic acid templated transcription	GO:0097659	181	0.026
cellular aromatic compound metabolic process	GO:0006725	295	0.026
regulation of primary metabolic process	GO:0080090	311	0.025
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.025
transcription from rna polymerase ii promoter	GO:0006366	80	0.025
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.024
central nervous system development	GO:0007417	387	0.024
regulation of metabolic process	GO:0019222	359	0.024	Human
regulation of gene expression	GO:0010468	265	0.024
brain development	GO:0007420	293	0.023
response to stress	GO:0006950	263	0.022
biosynthetic process	GO:0009058	294	0.022
embryonic organ development	GO:0048568	381	0.022
wound healing	GO:0042060	90	0.021
positive regulation of biological process	GO:0048518	253	0.021	Human Rat
regulation of macromolecule biosynthetic process	GO:0010556	225	0.021
negative regulation of response to stimulus	GO:0048585	104	0.021	Human
embryonic skeletal system development	GO:0048706	97	0.020
neuron projection regeneration	GO:0031102	16	0.020
retina development in camera type eye	GO:0060041	146	0.020
primary neural tube formation	GO:0014020	1	0.020
regulation of gtpase activity	GO:0043087	2	0.020
positive regulation of cellular metabolic process	GO:0031325	94	0.019	Human
embryonic organ morphogenesis	GO:0048562	274	0.018
head development	GO:0060322	303	0.018
positive regulation of notch signaling pathway	GO:0045747	3	0.018
regulation of intracellular signal transduction	GO:1902531	57	0.017	Human
aging	GO:0007568	2	0.017
cellular response to organic substance	GO:0071310	105	0.017	Rat
neuron differentiation	GO:0030182	353	0.017	Rat
aorta development	GO:0035904	4	0.016
tissue regeneration	GO:0042246	74	0.016
sensory organ morphogenesis	GO:0090596	200	0.016
apoptotic process	GO:0006915	116	0.016
regulation of signaling	GO:0023051	235	0.016	Human
multicellular organism growth	GO:0035264	4	0.015
negative regulation of signal transduction	GO:0009968	94	0.015	Human
protein localization to nucleus	GO:0034504	3	0.015
embryonic skeletal system morphogenesis	GO:0048704	93	0.015
positive regulation of cellular catabolic process	GO:0031331	3	0.015
regulation of biosynthetic process	GO:0009889	250	0.015
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.015
heart development	GO:0007507	313	0.015
negative regulation of cellular process	GO:0048523	283	0.014	Human Rat
glial cell migration	GO:0008347	3	0.014
signal transduction	GO:0007165	455	0.014	Human Rat
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.014
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.014
lipid storage	GO:0019915	1	0.014
growth	GO:0040007	174	0.013
response to organic substance	GO:0010033	153	0.013	Rat
skeletal system morphogenesis	GO:0048705	102	0.013
cell projection morphogenesis	GO:0048858	244	0.012
programmed cell death	GO:0012501	119	0.012
cell morphogenesis	GO:0000902	289	0.012
regulation of gtp catabolic process	GO:0033124	2	0.012
angiogenesis	GO:0001525	158	0.012
embryonic limb morphogenesis	GO:0030326	2	0.012
neuron projection morphogenesis	GO:0048812	161	0.012
cell projection organization	GO:0030030	284	0.012	Rat
gtp metabolic process	GO:0046039	4	0.012
guanosine containing compound catabolic process	GO:1901069	2	0.012
positive regulation of purine nucleotide catabolic process	GO:0033123	1	0.012
cell part morphogenesis	GO:0032990	246	0.011
neuron projection development	GO:0031175	180	0.011	Rat
eye morphogenesis	GO:0048592	144	0.011
maintenance of location	GO:0051235	4	0.011
gtp catabolic process	GO:0006184	2	0.011
stem cell proliferation	GO:0072089	4	0.011
cellular response to organic cyclic compound	GO:0071407	38	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.011
negative regulation of biological process	GO:0048519	304	0.011	Human Rat
cell death	GO:0008219	121	0.011
muscle structure development	GO:0061061	196	0.010
regulation of ras gtpase activity	GO:0032318	2	0.010
regulation of phosphorus metabolic process	GO:0051174	43	0.010	Human
regulation of cellular ketone metabolic process	GO:0010565	7	0.010
epithelium regeneration	GO:1990399	14	0.010
negative regulation of signaling	GO:0023057	96	0.010	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.010
regulation of purine nucleotide catabolic process	GO:0033121	2	0.010

magi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.016
heart disease	DOID:114	0.011
cardiovascular system disease	DOID:1287	0.011

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