Danio rerio

0 known processes

pi4k2a

phosphatidylinositol 4-kinase type 2 alpha

(Aliases: pi4kII alpha,zgc:63646,wu:fc84f05,pi4kii)

pi4k2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.166
signal transductionGO:00071654550.105
maintenance of locationGO:005123540.074
embryonic organ developmentGO:00485683810.064
lipid storageGO:001991510.062
developmental programmed cell deathGO:001062340.062
transportGO:00068102200.061
organelle fusionGO:004828430.060
modification dependent protein catabolic processGO:001994130.059
proteasomal protein catabolic processGO:001049820.058
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.058
agingGO:000756820.057
negative regulation of cellular processGO:00485232830.056
multicellular organism growthGO:003526440.053
regulation of bindingGO:005109830.051
establishment of localizationGO:00512342440.050
ubiquitin dependent protein catabolic processGO:000651130.050
autophagyGO:000691440.048
apoptotic process involved in developmentGO:190274220.047
proteolysis involved in cellular protein catabolic processGO:005160330.047
regulation of signal transductionGO:00099662250.047
modification dependent macromolecule catabolic processGO:004363230.046
single organism membrane fusionGO:004480120.045
intracellular signal transductionGO:0035556850.044
response to unfolded proteinGO:000698620.044
morphogenesis of an epitheliumGO:00020093330.044
positive regulation of catabolic processGO:000989640.043
sensory organ developmentGO:00074233930.042
cellular protein catabolic processGO:004425740.042
extrinsic apoptotic signaling pathwayGO:009719130.041
female sex differentiationGO:004666040.041
positive regulation of cell cycleGO:004578730.041
regulation of signalingGO:00230512350.040
cellular response to starvationGO:000926710.040
cell projection organizationGO:00300302840.040
tissue remodelingGO:004877140.040
positive regulation of cellular catabolic processGO:003133130.039
heart morphogenesisGO:00030071560.038
regulation of multicellular organism growthGO:004001440.038
immune system processGO:00023762410.038
regulation of protein catabolic processGO:004217610.038
developmental growthGO:00485891660.038
meiotic nuclear divisionGO:000712640.037
glial cell migrationGO:000834730.037
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.037
response to chemicalGO:00422213200.037
regulation of synapse organizationGO:005080730.037
regulation of biological qualityGO:00650082630.036
regulation of reproductive processGO:200024140.036
single organism transportGO:00447652060.036
generation of neuronsGO:00486993850.035
locomotionGO:00400113130.035
embryonic limb morphogenesisGO:003032620.035
positive regulation of transportGO:005105020.034
synaptic vesicle localizationGO:009747910.034
cell projection morphogenesisGO:00488582440.033
positive regulation of cellular component biogenesisGO:004408930.033
regulation of cell communicationGO:00106462320.033
regulation of protein complex assemblyGO:004325430.033
synaptic growth at neuromuscular junctionGO:005112420.033
regulation of extrinsic apoptotic signaling pathwayGO:200123630.033
cellular response to topologically incorrect proteinGO:003596720.032
regulation of synaptic growth at neuromuscular junctionGO:000858210.032
cellular response to external stimulusGO:007149620.032
multi organism processGO:00517041340.032
response to topologically incorrect proteinGO:003596620.032
cellular amine metabolic processGO:004410620.032
negative regulation of protein phosphorylationGO:000193340.032
camera type eye developmentGO:00430102220.031
macroautophagyGO:001623610.030
embryonic organ morphogenesisGO:00485622740.030
positive regulation of biological processGO:00485182530.030
axon developmentGO:00615641660.029
regulation of intracellular signal transductionGO:1902531570.029
regulation of protein modification by small protein conjugation or removalGO:190332030.029
er nucleus signaling pathwayGO:000698420.029
hemopoiesisGO:00300971830.029
neuron developmentGO:00486662620.029
development of primary female sexual characteristicsGO:004654540.029
regulation of synapse assemblyGO:005196330.028
mitochondrion organizationGO:000700540.028
cellular component movementGO:00069283350.028
amine metabolic processGO:000930820.028
growthGO:00400071740.027
establishment of protein localization to organelleGO:007259440.027
embryo development ending in birth or egg hatchingGO:00097922710.027
single organism localizationGO:19025782250.027
synaptic vesicle transportGO:004848910.027
guanosine containing compound catabolic processGO:190106920.027
neuron differentiationGO:00301823530.027
i kappab kinase nf kappab signalingGO:000724940.027
tube morphogenesisGO:00352393490.027
nucleobase containing compound metabolic processGO:00061392740.026
endoplasmic reticulum unfolded protein responseGO:003096820.026
regulation of cell shapeGO:000836010.026
cellular response to extracellular stimulusGO:003166820.026
immune system developmentGO:00025201910.026
odontogenesis of dentin containing toothGO:004247510.025
oxoacid metabolic processGO:0043436310.025
cellular macromolecule metabolic processGO:00442603910.025
regulation of cytokine productionGO:000181730.025
gtp metabolic processGO:004603940.025
cell deathGO:00082191210.025
embryonic heart tube developmentGO:00350501330.025
membrane fusionGO:006102520.025
negative regulation of cell communicationGO:0010648960.025
guanosine containing compound metabolic processGO:190106840.025
regulation of metabolic processGO:00192223590.025
positive regulation of i kappab kinase nf kappab signalingGO:004312330.024
cellular response to nutrient levelsGO:003166920.024
cellular ketone metabolic processGO:0042180110.024
spermatid differentiationGO:004851520.024
regulation of nucleoside metabolic processGO:000911820.024
organelle organizationGO:00069962270.024
organic acid metabolic processGO:0006082310.023
regulation of cellular amine metabolic processGO:003323800.023
negative regulation of signalingGO:0023057960.023
phagocytosisGO:000690930.023
cell part morphogenesisGO:00329902460.023
response to organic substanceGO:00100331530.023
vacuolar transportGO:000703420.023
regulation of cellular ketone metabolic processGO:001056570.023
establishment of synaptic vesicle localizationGO:009748010.023
negative regulation of signal transductionGO:0009968940.023
central nervous system developmentGO:00074173870.023
female gonad developmentGO:000858540.023
regulation of metal ion transportGO:001095940.022
negative regulation of protein kinase activityGO:000646940.022
cell morphogenesis involved in differentiationGO:00009041950.022
cell morphogenesisGO:00009022890.022
regulation of cellular amino acid metabolic processGO:000652100.022
cellular component disassemblyGO:002241110.022
endosomal transportGO:001619720.022
epithelial tube morphogenesisGO:00605621480.022
g1 s transition of mitotic cell cycleGO:000008210.022
regulation of nucleotide catabolic processGO:003081120.021
protein polyubiquitinationGO:000020940.021
gtp catabolic processGO:000618420.021
centrosome organizationGO:005129710.021
golgi vesicle transportGO:004819330.021
fertilizationGO:000956630.021
response to stressGO:00069502630.021
positive regulation of stress activated mapk cascadeGO:003287430.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
regulation of cell projection assemblyGO:006049140.021
membrane invaginationGO:001032410.021
adult behaviorGO:003053420.021
cellular amino acid metabolic processGO:000652070.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
cellular component morphogenesisGO:00329893360.021
stem cell maintenanceGO:001982740.020
brain developmentGO:00074202930.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
regulation of autophagyGO:001050630.020
leukocyte proliferationGO:007066110.020
digestive system developmentGO:00551232890.020
compound eye developmentGO:004874920.020
regulation of response to stimulusGO:00485832690.019
regulation of response to extracellular stimulusGO:003210410.019
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.019
cellular response to unfolded proteinGO:003462020.019
negative regulation of response to stimulusGO:00485851040.019
positive regulation of nucleotide catabolic processGO:003081310.019
post embryonic morphogenesisGO:000988640.019
positive regulation of map kinase activityGO:004340630.019
meiotic cell cycle processGO:190304630.019
eye developmentGO:00016542770.019
chordate embryonic developmentGO:00430092710.019
synaptic vesicle recyclingGO:003646510.018
cellular protein metabolic processGO:00442671290.018
post embryonic organ developmentGO:004856940.018
regulation of programmed cell deathGO:00430671010.018
small gtpase mediated signal transductionGO:000726480.018
apoptotic process involved in morphogenesisGO:006056120.018
signal transduction in absence of ligandGO:003803410.018
stem cell proliferationGO:007208940.018
digestive tract developmentGO:00485652650.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
heart developmentGO:00075073130.017
embryonic heart tube morphogenesisGO:00031431080.017
regulation of cellular component organizationGO:0051128860.017
cellular response to radiationGO:007147840.017
protein metabolic processGO:00195381830.017
nitrogen compound metabolic processGO:00068073190.017
negative regulation of sequestering of calcium ionGO:005128340.017
neuron projection morphogenesisGO:00488121610.017
b cell activationGO:004211320.017
skeletal system developmentGO:00015011810.017
positive regulation of protein complex assemblyGO:003133420.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of meiotic cell cycleGO:005144510.017
small molecule metabolic processGO:0044281770.017
regulation of filopodium assemblyGO:005148920.017
cellular response to stressGO:0033554620.017
regulation of circadian rhythmGO:004275240.017
apoptotic processGO:00069151160.017
mononuclear cell proliferationGO:003294310.017
regulation of cytoplasmic transportGO:190364940.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
positive regulation of cytokine productionGO:000181920.016
regulation of tube sizeGO:003515020.016
regulation of gtp catabolic processGO:003312420.016
sequestering of metal ionGO:005123830.016
regulation of protein bindingGO:004339330.016
cellular response to chemical stimulusGO:00708871570.016
regulation of establishment of protein localizationGO:007020140.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
positive regulation of gtp catabolic processGO:003312610.016
regulation of apoptotic processGO:0042981980.016
response to uvGO:000941130.016
ovulation cycleGO:004269820.016
head developmentGO:00603223030.016
carboxylic acid metabolic processGO:0019752220.016
cell growthGO:0016049570.016
deathGO:00162651210.016
regulation of purine nucleotide catabolic processGO:003312120.016
macromolecule modificationGO:00434121110.016
regulation of protein ubiquitinationGO:003139630.016
microtubule organizing center organizationGO:003102310.016
sequestering of calcium ionGO:005120830.016
regulation of organ growthGO:004662030.016
regulation of blood vessel sizeGO:005088020.016
negative regulation of kinase activityGO:003367340.016
positive regulation of secretion by cellGO:190353210.016
positive regulation of purine nucleotide catabolic processGO:003312310.015
cellular component assemblyGO:00226071700.015
synaptic vesicle endocytosisGO:004848810.015
organic substance biosynthetic processGO:19015762890.015
axonogenesisGO:00074091520.015
neuron projection developmentGO:00311751800.015
regulation of gtpase activityGO:004308720.015
cell motilityGO:00488702440.015
response to nutrientGO:000758430.015
regulation of primary metabolic processGO:00800903110.015
regulation of nitrogen compound metabolic processGO:00511712510.015
centrosome cycleGO:000709810.015
regulation of response to cytokine stimulusGO:006075930.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
cytokinesisGO:000091030.015
regulation of synaptic plasticityGO:004816710.015
homeostasis of number of cellsGO:0048872620.015
actin polymerization or depolymerizationGO:000815420.015
single organism metabolic processGO:00447102170.015
single organism intracellular transportGO:1902582250.015
establishment of localization in cellGO:0051649770.015
localization of cellGO:00516742440.015
positive regulation of gtpase activityGO:004354710.015
mitochondrial transportGO:000683920.015
cellular response to light stimulusGO:007148240.014
organic cyclic compound biosynthetic processGO:19013622230.014
positive regulation of chromatin modificationGO:190331010.014
regulation of cellular protein catabolic processGO:190336210.014
cellular localizationGO:0051641970.014
peptidyl serine modificationGO:001820920.014
periodic partitioningGO:000736510.014
lymphocyte proliferationGO:004665110.014
positive regulation of cellular processGO:00485222010.014
embryonic skeletal system morphogenesisGO:0048704930.014
protein localization to nucleusGO:003450430.014
positive regulation of jnk cascadeGO:004633030.014
positive regulation of canonical wnt signaling pathwayGO:009026340.014
protein stabilizationGO:005082120.014
mitotic dna damage checkpointGO:004477340.014
lamellipodium organizationGO:009758110.014
protein modification processGO:00362111000.014
post golgi vesicle mediated transportGO:000689210.014
response to corticosteroidGO:003196010.014
regulation of cell deathGO:00109411030.014
organic cyclic compound metabolic processGO:19013603010.014
inorganic cation transmembrane transportGO:0098662500.014
positive regulation of dna metabolic processGO:005105410.014
leukocyte homeostasisGO:000177620.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
post embryonic organ morphogenesisGO:004856310.013
cytoskeleton dependent cytokinesisGO:006164030.013
nucleocytoplasmic transportGO:000691340.013
digestive tract morphogenesisGO:00485462310.013
sensory organ morphogenesisGO:00905962000.013
rna metabolic processGO:00160702190.013
gene expressionGO:00104672520.013
response to vitaminGO:003327330.013
nucleic acid metabolic processGO:00903042440.013
release of sequestered calcium ion into cytosolGO:005120930.013
regulation of calcium ion transportGO:005192420.013
response to hydrogen peroxideGO:004254230.013
long chain fatty acid metabolic processGO:000167610.013
exocytosisGO:000688710.013
ovulation cycle processGO:002260220.013
regulation of multicellular organismal processGO:00512392770.013
regulation of blood pressureGO:000821710.013
regulation of cell activationGO:005086510.013
lateral inhibitionGO:004633110.013
cell migrationGO:00164772370.013
myeloid cell homeostasisGO:0002262560.013
regulation of catalytic activityGO:0050790550.013
inositol lipid mediated signalingGO:004801720.013
negative regulation of synapse assemblyGO:005196420.013
peptidyl serine phosphorylationGO:001810510.013
programmed cell deathGO:00125011190.013
negative regulation of biological processGO:00485193040.013
cellular response to organic substanceGO:00713101050.013
ear developmentGO:00435831270.013
positive regulation of secretionGO:005104710.013
cortical actin cytoskeleton organizationGO:003086610.013
endocrine processGO:005088620.013
protein k48 linked ubiquitinationGO:007093610.012
stem cell fate commitmentGO:004886510.012
positive regulation of metabolic processGO:00098931080.012
regulation of mitochondrion organizationGO:001082110.012
regulation of neurotransmitter secretionGO:004692810.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
cell agingGO:000756920.012
retina development in camera type eyeGO:00600411460.012
phosphorylationGO:0016310690.012
gastrulationGO:00073692080.012
hormone biosynthetic processGO:004244630.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
wnt signaling pathwayGO:0016055800.012
regulation of jak stat cascadeGO:004642530.012
calcium ion transport into cytosolGO:006040230.012
b cell differentiationGO:003018310.012
positive regulation of protein polymerizationGO:003227320.012
cellular biosynthetic processGO:00442492860.012
phosphorus metabolic processGO:00067931090.012
negative regulation of defense responseGO:003134820.012
appendage developmentGO:0048736800.012
cartilage developmentGO:0051216960.012
negative regulation of response to cytokine stimulusGO:006076120.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of developmental processGO:00507932470.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
small molecule catabolic processGO:004428230.012
lipid metabolic processGO:0006629520.012
response to external stimulusGO:00096052640.012
secondary metabolic processGO:001974830.012
ion transportGO:00068111140.012
phosphate containing compound metabolic processGO:00067961080.012
actin filament polymerizationGO:003004120.012
regulation of stem cell differentiationGO:200073640.012
double strand break repairGO:000630230.012
convergent extensionGO:00600261180.012
germ line stem cell maintenanceGO:003071820.011
single organism nuclear importGO:190259330.011
protein secretionGO:000930610.011
entrainment of circadian clockGO:000964920.011
response to xenobiotic stimulusGO:0009410450.011
spermatid developmentGO:000728620.011
activation of mapk activityGO:000018730.011
skeletal system morphogenesisGO:00487051020.011
mitotic dna integrity checkpointGO:004477440.011
protein phosphorylationGO:0006468470.011
cell cycle g1 s phase transitionGO:004484310.011
spindle assemblyGO:005122520.011
heterocycle biosynthetic processGO:00181302150.011
positive regulation of cytoskeleton organizationGO:005149530.011
response to drugGO:004249330.011
negative regulation of reproductive processGO:200024230.011
cellular protein modification processGO:00064641000.011
positive regulation of response to stimulusGO:0048584800.011
negative regulation of multi organism processGO:004390130.011
vesicle localizationGO:0051648270.011
positive regulation of protein kinase b signalingGO:005189710.011
nuclear importGO:005117030.011
intracellular transportGO:0046907320.011
negative regulation of nuclear divisionGO:005178430.011
single organism organelle organizationGO:19025891990.011
negative regulation of map kinase activityGO:004340720.011
cellular nitrogen compound metabolic processGO:00346412900.011
cellular lipid metabolic processGO:0044255360.011
regulation of protein localization to nucleusGO:190018020.011
regulation of organelle assemblyGO:190211540.011
protein homooligomerizationGO:005126030.011
embryonic viscerocranium morphogenesisGO:0048703520.011
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.011
protein localization to plasma membraneGO:007265910.011
homeostasis of number of cells within a tissueGO:004887340.011
ras protein signal transductionGO:000726570.011
cellular lipid catabolic processGO:004424230.011
osteoclast differentiationGO:003031610.011
nuclear transportGO:005116940.011
translational initiationGO:000641330.011
cell surface receptor signaling pathwayGO:00071663250.011
fatty acid transportGO:001590810.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
nucleic acid templated transcriptionGO:00976591810.010
regulation of nervous system developmentGO:0051960900.010
endosome organizationGO:000703220.010
ovarian follicle developmentGO:000154120.010
regulation of neurogenesisGO:0050767870.010
organic acid catabolic processGO:001605430.010
blood vessel developmentGO:00015682460.010
blood vessel morphogenesisGO:00485142160.010
cell substrate adhesionGO:003158940.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
neurotransmitter secretionGO:000726920.010
regulation of transporter activityGO:003240920.010
ion transmembrane transportGO:0034220910.010
regulation of protein transportGO:005122330.010
regulation of multicellular organismal developmentGO:20000262230.010
neurotransmitter transportGO:000683620.010
meiosis iGO:000712710.010
actin filament based movementGO:003004810.010
regulation of response to nutrient levelsGO:003210710.010
positive regulation of immune effector processGO:000269930.010
positive regulation of myeloid cell differentiationGO:004563920.010
nuclear exportGO:005116810.010
negative regulation of stem cell differentiationGO:200073720.010
dicarboxylic acid transportGO:000683510.010
cortical cytoskeleton organizationGO:003086510.010
protein polymerizationGO:005125840.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
connective tissue developmentGO:0061448990.010
protein importGO:001703830.010
regulation of cellular biosynthetic processGO:00313262450.010

pi4k2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.019
disease of metabolismDOID:001466700.015
musculoskeletal system diseaseDOID:1700.014
cardiovascular system diseaseDOID:128700.012