Danio rerio

32 known processes

ttnb

titin b

(Aliases: si:dZ167C3.1,ttnl,im:6911926,TTN,hm:zeh1256r,si:dz249n21.1,wu:fc09a12)

ttnb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ventricular cardiac myofibril assemblyGO:005500540.909
striated muscle cell developmentGO:00550021080.795
cellular component assemblyGO:00226071700.757
muscle cell differentiationGO:00426921390.739
striated muscle cell differentiationGO:00511461290.730
cellular component assembly involved in morphogenesisGO:00109271070.726
somitogenesisGO:0001756870.654
heart processGO:0003015710.632
muscle cell developmentGO:00550011150.589
actin cytoskeleton organizationGO:0030036630.506
muscle structure developmentGO:00610611960.496
heart developmentGO:00075073130.489
cardiac muscle cell differentiationGO:0055007300.468
sarcomere organizationGO:0045214260.465
cellular component biogenesisGO:00440851780.450
system processGO:00030081850.440
cardiac muscle tissue developmentGO:0048738480.397
neuron differentiationGO:00301823530.360
organic substance biosynthetic processGO:19015762890.342
myofibril assemblyGO:0030239480.337
neuron developmentGO:00486662620.311
circulatory system processGO:0003013870.295
cardiac muscle fiber developmentGO:004873930.280
cellular component morphogenesisGO:00329893360.273
cardiac cell developmentGO:0055006210.271
actomyosin structure organizationGO:0031032530.267
muscle system processGO:0003012200.264
blood circulationGO:0008015870.244
nitrogen compound metabolic processGO:00068073190.241
actin filament based processGO:0030029640.237
neuron projection developmentGO:00311751800.220
anterior posterior pattern specificationGO:00099521520.188
ventricular cardiac muscle cell differentiationGO:005501260.178
somite developmentGO:0061053960.174
skeletal muscle organ developmentGO:0060538780.164
segmentationGO:0035282970.162
heart morphogenesisGO:00030071560.151
alternative mrna splicing via spliceosomeGO:000038010.150
organophosphate biosynthetic processGO:0090407230.148
cellular biosynthetic processGO:00442492860.143
determination of bilateral symmetryGO:00098552040.138
specification of symmetryGO:00097992040.137
regulation of macromolecule metabolic processGO:00602553170.137
organonitrogen compound metabolic processGO:1901564740.136
embryo development ending in birth or egg hatchingGO:00097922710.136
single organism organelle organizationGO:19025891990.130
fatty acid catabolic processGO:000906210.130
regulation of ion transmembrane transporter activityGO:003241220.129
regulation of muscle contractionGO:000693730.128
cardiocyte differentiationGO:0035051440.126
anatomical structure homeostasisGO:0060249360.121
organelle organizationGO:00069962270.118
cell projection morphogenesisGO:00488582440.116
striated muscle tissue developmentGO:00147061100.115
pyruvate metabolic processGO:000609010.115
heart valve formationGO:000318840.114
negative regulation of biological processGO:00485193040.111
chordate embryonic developmentGO:00430092710.107
regulation of metabolic processGO:00192223590.103
cellular aromatic compound metabolic processGO:00067252950.101
ventricular cardiac muscle tissue morphogenesisGO:005501020.098
immune system developmentGO:00025201910.089
lipid storageGO:001991510.088
regulation of blood circulationGO:1903522320.086
regulation of gene expressionGO:00104682650.084
behaviorGO:0007610740.083
neuromuscular synaptic transmissionGO:000727420.082
regulation of heart contractionGO:0008016320.082
agingGO:000756820.081
larval developmentGO:000216420.080
biological adhesionGO:0022610400.078
cardiac muscle cell developmentGO:0055013200.075
organic acid metabolic processGO:0006082310.071
regulation of transmembrane transporter activityGO:002289820.068
organic cyclic compound biosynthetic processGO:19013622230.064
single organism biosynthetic processGO:0044711710.063
calcium ion homeostasisGO:0055074190.063
regionalizationGO:00030022740.062
forebrain midbrain boundary formationGO:002190510.062
oogenesisGO:0048477140.062
maintenance of locationGO:005123540.060
muscle organ developmentGO:00075171010.058
cell part morphogenesisGO:00329902460.058
development of primary female sexual characteristicsGO:004654540.058
positive regulation of biological processGO:00485182530.057
purine ribonucleoside monophosphate catabolic processGO:000916940.055
generation of neuronsGO:00486993850.055
organic cyclic compound metabolic processGO:19013603010.054
small molecule catabolic processGO:004428230.054
oxoacid metabolic processGO:0043436310.053
cell projection organizationGO:00300302840.052
digestive system developmentGO:00551232890.052
regulation of system processGO:0044057400.052
determination of left right symmetryGO:00073681790.051
positive regulation of blood circulationGO:190352420.051
muscle contractionGO:0006936180.050
cardiac ventricle formationGO:000321110.050
cellular response to hormone stimulusGO:0032870390.049
regulation of transporter activityGO:003240920.048
heart loopingGO:0001947940.048
regulation of cellular macromolecule biosynthetic processGO:20001122220.047
carboxylic acid metabolic processGO:0019752220.046
positive regulation of heart contractionGO:004582320.046
heart contractionGO:0060047710.045
stem cell differentiationGO:00488631170.044
positive regulation of transportGO:005105020.043
regulation of cellular component organizationGO:0051128860.043
ventricular cardiac muscle tissue developmentGO:000322930.041
cellular nitrogen compound metabolic processGO:00346412900.040
heterocycle metabolic processGO:00464832900.040
regulation of nucleobase containing compound metabolic processGO:00192192500.040
regulation of response to stimulusGO:00485832690.040
regulation of cell communicationGO:00106462320.039
cell morphogenesis involved in neuron differentiationGO:00486671630.039
cellular nitrogen compound biosynthetic processGO:00442712180.039
regulation of primary metabolic processGO:00800903110.038
cytoskeleton organizationGO:0007010960.038
muscle organ morphogenesisGO:004864480.038
female gamete generationGO:0007292140.038
cell morphogenesisGO:00009022890.037
limb bud formationGO:006017420.036
immune system processGO:00023762410.036
embryonic organ developmentGO:00485683810.036
adult behaviorGO:003053420.036
positive regulation of cellular amino acid metabolic processGO:004576400.035
locomotionGO:00400113130.034
cell morphogenesis involved in differentiationGO:00009041950.034
somatic muscle developmentGO:000752540.033
axonogenesisGO:00074091520.033
biosynthetic processGO:00090582940.033
mitotic cell cycle processGO:1903047480.032
regulation of purine nucleotide catabolic processGO:003312120.032
regulation of blood pressureGO:000821710.032
cellular lipid catabolic processGO:004424230.032
positive regulation of nitrogen compound metabolic processGO:0051173690.032
regulation of multicellular organismal processGO:00512392770.031
regulation of tube sizeGO:003515020.031
lateral line system developmentGO:0048925760.031
small molecule metabolic processGO:0044281770.031
cell projection assemblyGO:0030031640.031
gene expressionGO:00104672520.030
rna metabolic processGO:00160702190.030
embryonic organ morphogenesisGO:00485622740.030
regulation of cellular biosynthetic processGO:00313262450.030
patterning of blood vesselsGO:0001569150.029
cellular macromolecule biosynthetic processGO:00346452240.029
macromolecule biosynthetic processGO:00090592270.029
multi organism processGO:00517041340.029
response to endogenous stimulusGO:0009719830.028
regulation of signal transductionGO:00099662250.028
response to organic substanceGO:00100331530.028
purine nucleoside monophosphate catabolic processGO:000912840.028
regulation of synapse organizationGO:005080730.028
er nucleus signaling pathwayGO:000698420.027
nucleobase containing compound metabolic processGO:00061392740.027
response to external stimulusGO:00096052640.027
endocardial cushion formationGO:000327220.027
regulation of cell matrix adhesionGO:000195210.026
regulation of anatomical structure morphogenesisGO:00226031300.026
cellular lipid metabolic processGO:0044255360.026
cardiac chamber formationGO:000320740.026
cellular protein metabolic processGO:00442671290.026
fatty acid beta oxidationGO:000663510.026
monocarboxylic acid catabolic processGO:007232930.026
regulation of programmed cell deathGO:00430671010.026
positive regulation of metabolic processGO:00098931080.026
regulation of nucleotide catabolic processGO:003081120.025
muscle fiber developmentGO:0048747520.025
hemopoiesisGO:00300971830.025
atp catabolic processGO:000620040.025
cellular response to unfolded proteinGO:003462020.025
post embryonic organ developmentGO:004856940.025
response to unfolded proteinGO:000698620.025
regulation of cardiac muscle contractionGO:005511720.025
cardiac muscle tissue morphogenesisGO:005500870.024
wound healingGO:0042060900.024
establishment of localizationGO:00512342440.024
purine containing compound metabolic processGO:0072521290.024
brain developmentGO:00074202930.024
nephron tubule epithelial cell differentiationGO:007216010.024
hematopoietic or lymphoid organ developmentGO:00485341910.023
germ cell developmentGO:0007281220.023
mesoderm developmentGO:0007498880.023
organophosphate metabolic processGO:0019637370.023
cell substrate adhesionGO:003158940.023
sensory organ developmentGO:00074233930.023
positive regulation of skeletal muscle tissue developmentGO:004864310.023
cellular response to chemical stimulusGO:00708871570.023
endocardial cushion morphogenesisGO:000320330.023
heterocycle biosynthetic processGO:00181302150.022
muscle tissue developmentGO:00605371100.022
endoplasmic reticulum unfolded protein responseGO:003096820.022
positive regulation of muscle cell differentiationGO:005114910.022
regulation of cytoplasmic transportGO:190364940.022
fertilizationGO:000956630.022
negative regulation of cellular processGO:00485232830.022
sequestering of metal ionGO:005123830.022
venous blood vessel morphogenesisGO:004884530.022
regulation of biosynthetic processGO:00098892500.021
response to stressGO:00069502630.021
organelle assemblyGO:00709251100.021
lipid oxidationGO:003444010.021
regulation of metal ion transportGO:001095940.020
developmental growthGO:00485891660.020
cognitionGO:005089010.020
eye developmentGO:00016542770.020
connective tissue developmentGO:0061448990.019
protein metabolic processGO:00195381830.019
regulation of blood vessel sizeGO:005088020.018
lymphoid lineage cell migrationGO:009753440.018
cell adhesionGO:0007155400.018
sex determinationGO:000753010.018
cellular amino acid metabolic processGO:000652070.018
regulation of sequestering of calcium ionGO:005128240.018
rna biosynthetic processGO:00327741810.018
cellular calcium ion homeostasisGO:0006874130.018
determination of heart left right asymmetryGO:00613711170.018
regulation of nucleoside metabolic processGO:000911820.018
neuron projection morphogenesisGO:00488121610.018
regulation of protein bindingGO:004339330.018
nucleocytoplasmic transportGO:000691340.018
synaptic growth at neuromuscular junctionGO:005112420.017
regulation of biological qualityGO:00650082630.017
organic acid catabolic processGO:001605430.017
nucleic acid metabolic processGO:00903042440.017
nucleoside monophosphate catabolic processGO:000912540.017
regulation of alternative mrna splicing via spliceosomeGO:000038110.017
pigmentationGO:0043473850.017
purine ribonucleotide metabolic processGO:0009150270.017
phosphorus metabolic processGO:00067931090.017
lipid metabolic processGO:0006629520.016
axonal fasciculationGO:0007413110.016
single organism reproductive processGO:0044702400.016
establishment of protein localization to plasma membraneGO:009000210.016
signal transductionGO:00071654550.016
regulation of calcium ion transportGO:005192420.016
single organism transportGO:00447652060.016
multi organism reproductive processGO:0044703360.016
ear developmentGO:00435831270.015
ventricular cardiac muscle cell developmentGO:005501550.015
nucleobase containing compound biosynthetic processGO:00346542050.015
negative regulation of translationGO:001714810.015
developmental maturationGO:0021700340.015
regulation of signalingGO:00230512350.015
nucleobase containing compound transportGO:001593120.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
single organism metabolic processGO:00447102170.015
intracellular signal transductionGO:0035556850.015
response to woundingGO:00096111160.015
circadian sleep wake cycleGO:004274520.014
positive regulation of cellular amine metabolic processGO:003324000.014
purine nucleotide metabolic processGO:0006163270.014
growthGO:00400071740.014
sensory system developmentGO:0048880760.014
carboxylic acid catabolic processGO:004639530.014
organonitrogen compound biosynthetic processGO:1901566470.014
epithelial tube morphogenesisGO:00605621480.014
morphogenesis of an epitheliumGO:00020093330.014
calcium mediated signalingGO:001972220.014
mesenchyme developmentGO:00604851270.014
programmed cell deathGO:00125011190.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
regulation of apoptotic processGO:0042981980.013
fatty acid oxidationGO:001939510.013
regulation of cellular metabolic processGO:00313233200.013
morphogenesis of an epithelial sheetGO:0002011490.013
establishment of epithelial cell polarityGO:009016220.013
cellular protein modification processGO:00064641000.013
skeletal muscle tissue developmentGO:0007519670.013
cellular response to extracellular stimulusGO:003166820.013
water homeostasisGO:003010440.013
regulation of catalytic activityGO:0050790550.013
cellular modified amino acid metabolic processGO:000657530.013
central nervous system developmentGO:00074173870.013
axon developmentGO:00615641660.013
regulation of reproductive processGO:200024140.013
cell matrix adhesionGO:000716040.013
response to amino acidGO:004320020.013
cell motilityGO:00488702440.013
regulation of cell projection assemblyGO:006049140.012
taxisGO:00423301090.012
cellular component movementGO:00069283350.012
camera type eye morphogenesisGO:00485931080.012
regulation of cell shapeGO:000836010.012
sequestering of calcium ionGO:005120830.012
lymphoid lineage cell migration into thymusGO:009753540.012
sexual reproductionGO:0019953360.012
fibril organizationGO:009743510.012
regulation of circadian rhythmGO:004275240.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
regulation of cell activationGO:005086510.012
response to glucocorticoidGO:005138410.012
vasculature developmentGO:00019442780.012
positive regulation of cellular catabolic processGO:003133130.012
single organism nuclear importGO:190259330.012
regulation of bindingGO:005109830.012
regulation of macromolecule biosynthetic processGO:00105562250.011
cardiac muscle cell contractionGO:008600310.011
phosphate containing compound metabolic processGO:00067961080.011
protein localization to nucleusGO:003450430.011
regulation of nitrogen compound metabolic processGO:00511712510.011
protein complex subunit organizationGO:0071822460.011
digestive tract developmentGO:00485652650.011
response to corticosteroidGO:003196010.011
ribonucleoside monophosphate catabolic processGO:000915840.011
skeletal muscle fiber developmentGO:0048741350.011
single organism carbohydrate metabolic processGO:0044723120.011
establishment of protein localization to organelleGO:007259440.011
homeostasis of number of cellsGO:0048872620.011
embryonic heart tube morphogenesisGO:00031431080.011
macromolecule modificationGO:00434121110.011
cellular amine metabolic processGO:004410620.011
regulation of molecular functionGO:0065009700.011
phagocytosis engulfmentGO:000691110.011
nuclear importGO:005117030.011
positive regulation of cellular metabolic processGO:0031325940.010
regulation of multicellular organism growthGO:004001440.010
cell cycleGO:0007049930.010
skeletal muscle thin filament assemblyGO:003024040.010
cellular response to topologically incorrect proteinGO:003596720.010
oocyte developmentGO:0048599140.010
homeostatic processGO:00425921420.010

ttnb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.187
musculoskeletal system diseaseDOID:1700.145
muscle tissue diseaseDOID:6600.145
cardiomyopathyDOID:005070000.145
heart diseaseDOID:11400.145
cardiovascular system diseaseDOID:128700.145
muscular diseaseDOID:008000000.145
myopathyDOID:42300.145
nervous system diseaseDOID:86300.011
colon cancerDOID:21900.010
large intestine cancerDOID:567200.010
gastrointestinal system cancerDOID:311900.010
organ system cancerDOID:005068600.010
cancerDOID:16200.010
colorectal cancerDOID:925600.010
disease of cellular proliferationDOID:1456600.010
intestinal cancerDOID:1015500.010