Danio rerio

40 known processes

ttna

titin a

(Aliases: wu:fi04b11,fi20g08,ttn,si:busm1-258d18.1,wu:fi20g08,si:dz258d18.1)

ttna biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
striated muscle cell differentiationGO:00511461291.000
muscle structure developmentGO:00610611961.000
striated muscle cell developmentGO:00550021081.000
muscle cell developmentGO:00550011151.000
actomyosin structure organizationGO:0031032530.999
actin filament based processGO:0030029640.999
muscle cell differentiationGO:00426921390.999
myofibril assemblyGO:0030239480.999
heart processGO:0003015710.999
heart developmentGO:00075073130.997
organelle assemblyGO:00709251100.997
cardiac muscle cell differentiationGO:0055007300.993
heart morphogenesisGO:00030071560.989
single organism organelle organizationGO:19025891990.988
epithelial tube morphogenesisGO:00605621480.986
blood circulationGO:0008015870.986
muscle system processGO:0003012200.983
cardiac muscle tissue developmentGO:0048738480.982
regulation of blood circulationGO:1903522320.980
neuron projection developmentGO:00311751800.972
cell projection organizationGO:00300302840.967
muscle contractionGO:0006936180.964
neuron differentiationGO:00301823530.961
cellular component assembly involved in morphogenesisGO:00109271070.958
tube morphogenesisGO:00352393490.951
morphogenesis of an epitheliumGO:00020093330.949
ventricular cardiac muscle cell differentiationGO:005501260.946
circulatory system processGO:0003013870.940
ventricular cardiac muscle tissue morphogenesisGO:005501020.937
actin cytoskeleton organizationGO:0030036630.933
cellular component morphogenesisGO:00329893360.930
heart contractionGO:0060047710.923
regulation of system processGO:0044057400.908
sarcomere organizationGO:0045214260.903
regulation of muscle contractionGO:000693730.902
cellular component assemblyGO:00226071700.898
embryonic organ developmentGO:00485683810.896
locomotionGO:00400113130.874
cytoskeleton organizationGO:0007010960.868
embryonic heart tube developmentGO:00350501330.862
cardiocyte differentiationGO:0035051440.854
organelle organizationGO:00069962270.845
muscle organ developmentGO:00075171010.828
embryo development ending in birth or egg hatchingGO:00097922710.800
regulation of heart contractionGO:0008016320.799
ventricular cardiac muscle tissue developmentGO:000322930.761
ventricular cardiac myofibril assemblyGO:005500540.758
heart loopingGO:0001947940.746
cardiac cell developmentGO:0055006210.713
cardiac muscle tissue morphogenesisGO:005500870.709
nitrogen compound metabolic processGO:00068073190.692
skeletal myofibril assemblyGO:001486670.652
somitogenesisGO:0001756870.649
single organism localizationGO:19025782250.641
skeletal muscle organ developmentGO:0060538780.627
axon developmentGO:00615641660.622
neuron developmentGO:00486662620.618
phosphorus metabolic processGO:00067931090.614
regulation of biological qualityGO:00650082630.595
positive regulation of transportGO:005105020.592
embryonic heart tube morphogenesisGO:00031431080.555
homeostasis of number of cellsGO:0048872620.551
cellular component biogenesisGO:00440851780.550
central nervous system developmentGO:00074173870.540
generation of neuronsGO:00486993850.535
cardiac muscle cell developmentGO:0055013200.532
regulation of cell matrix adhesionGO:000195210.516
cellular biosynthetic processGO:00442492860.512
determination of heart left right asymmetryGO:00613711170.504
system processGO:00030081850.497
cell morphogenesis involved in neuron differentiationGO:00486671630.489
convergent extensionGO:00600261180.473
striated muscle myosin thick filament assemblyGO:007168860.462
heart field specificationGO:000312810.460
muscle fiber developmentGO:0048747520.454
regulation of biosynthetic processGO:00098892500.424
cell part morphogenesisGO:00329902460.398
angiogenesisGO:00015251580.397
homeostatic processGO:00425921420.396
organic acid catabolic processGO:001605430.395
cell motilityGO:00488702440.387
cell morphogenesis involved in differentiationGO:00009041950.387
specification of symmetryGO:00097992040.386
cardiac muscle fiber developmentGO:004873930.386
striated muscle tissue developmentGO:00147061100.382
determination of left right symmetryGO:00073681790.379
cardiac chamber formationGO:000320740.376
small molecule metabolic processGO:0044281770.370
cardiac atrium morphogenesisGO:000320920.368
regulation of skeletal muscle fiber developmentGO:004874220.364
nucleic acid metabolic processGO:00903042440.340
determination of bilateral symmetryGO:00098552040.338
cellular nitrogen compound biosynthetic processGO:00442712180.337
axonogenesisGO:00074091520.336
cardiac ventricle formationGO:000321110.336
blood vessel developmentGO:00015682460.333
cation homeostasisGO:0055080330.332
heart valve formationGO:000318840.325
atrial cardiac myofibril assemblyGO:005500420.320
ion transmembrane transportGO:0034220910.318
regulation of multicellular organismal processGO:00512392770.307
post embryonic morphogenesisGO:000988640.307
positive regulation of blood circulationGO:190352420.306
cell matrix adhesionGO:000716040.302
cell substrate adhesionGO:003158940.294
outflow tract morphogenesisGO:000315110.291
regulation of heart rateGO:000202750.285
vasculature developmentGO:00019442780.282
regulation of macromolecule metabolic processGO:00602553170.280
signal transductionGO:00071654550.265
regulation of sarcomere organizationGO:006029720.263
regulation of multicellular organismal developmentGO:20000262230.257
lipid storageGO:001991510.257
head developmentGO:00603223030.256
regulation of organ growthGO:004662030.250
somatic muscle developmentGO:000752540.245
response to chemicalGO:00422213200.242
establishment of localizationGO:00512342440.240
myosin filament organizationGO:003103360.239
venous blood vessel morphogenesisGO:004884530.238
neuron projection morphogenesisGO:00488121610.235
taxisGO:00423301090.233
cellular component movementGO:00069283350.229
cell morphogenesisGO:00009022890.228
organonitrogen compound metabolic processGO:1901564740.225
cardiac chamber morphogenesisGO:0003206120.223
cell migrationGO:00164772370.216
cellular response to topologically incorrect proteinGO:003596720.212
transportGO:00068102200.212
stem cell differentiationGO:00488631170.202
positive regulation of skeletal muscle tissue developmentGO:004864310.202
patterning of blood vesselsGO:0001569150.200
muscle cell fate determinationGO:000752110.198
cardiac ventricle morphogenesisGO:000320870.195
regulation of locomotionGO:0040012550.192
transmembrane transportGO:00550851200.190
skeletal muscle thin filament assemblyGO:003024040.188
ventricular cardiac muscle cell developmentGO:005501550.185
heterocycle biosynthetic processGO:00181302150.185
regulation of cellular component organizationGO:0051128860.183
cell adhesionGO:0007155400.183
agingGO:000756820.182
negative regulation of axon guidanceGO:190266810.182
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.178
gene expressionGO:00104672520.178
regulation of cell communicationGO:00106462320.177
regulation of cell projection organizationGO:0031344440.165
regulation of cell developmentGO:00602841000.164
positive regulation of heart contractionGO:004582320.164
blood vessel morphogenesisGO:00485142160.159
muscle tissue morphogenesisGO:006041570.159
calcium ion homeostasisGO:0055074190.158
regulation of metabolic processGO:00192223590.157
chordate embryonic developmentGO:00430092710.156
polarized epithelial cell differentiationGO:003085940.155
myosin filament assemblyGO:003103460.155
regulation of anatomical structure morphogenesisGO:00226031300.154
calcium ion importGO:007050940.151
response to external stimulusGO:00096052640.151
negative regulation of multicellular organismal processGO:0051241690.149
regulation of glutamate receptor signaling pathwayGO:190044910.142
regulation of transmembrane transporter activityGO:002289820.140
regulation of response to stimulusGO:00485832690.140
circadian sleep wake cycle processGO:002241020.139
anatomical structure homeostasisGO:0060249360.135
macromolecule biosynthetic processGO:00090592270.135
ion transportGO:00068111140.132
ribonucleotide metabolic processGO:0009259270.132
regionalizationGO:00030022740.130
cell projection morphogenesisGO:00488582440.127
ribonucleoside monophosphate catabolic processGO:000915840.126
behaviorGO:0007610740.124
cellular aromatic compound metabolic processGO:00067252950.122
endoplasmic reticulum unfolded protein responseGO:003096820.122
skeletal muscle fiber developmentGO:0048741350.121
regulation of synapse organizationGO:005080730.121
response to stressGO:00069502630.121
regulation of cell proliferation involved in heart morphogenesisGO:200013620.120
regulation of cardiac muscle cell differentiationGO:200072510.120
mesoderm developmentGO:0007498880.119
regulation of cellular biosynthetic processGO:00313262450.118
chemotaxisGO:00069351040.116
regulation of tube sizeGO:003515020.115
erythrocyte homeostasisGO:0034101550.115
pharyngeal muscle developmentGO:004328240.114
atp catabolic processGO:000620040.114
immune system developmentGO:00025201910.114
metal ion homeostasisGO:0055065260.113
er nucleus signaling pathwayGO:000698420.111
protein complex subunit organizationGO:0071822460.109
negative regulation of cell communicationGO:0010648960.108
segmentationGO:0035282970.107
rna biosynthetic processGO:00327741810.107
cellular response to chemical stimulusGO:00708871570.107
heart formationGO:0060914130.107
brain developmentGO:00074202930.106
growthGO:00400071740.106
cellular nitrogen compound metabolic processGO:00346412900.104
somite developmentGO:0061053960.103
immune system processGO:00023762410.102
regulation of blood pressureGO:000821710.100
deathGO:00162651210.100
positive regulation of cellular processGO:00485222010.100
larval developmentGO:000216420.099
macromolecular complex assemblyGO:0065003350.099
circadian sleep wake cycle sleepGO:005080210.099
skeletal muscle tissue developmentGO:0007519670.097
purine nucleoside monophosphate catabolic processGO:000912840.095
regulation of skeletal muscle cell differentiationGO:200101410.095
sensory organ developmentGO:00074233930.095
anterior posterior pattern specificationGO:00099521520.094
regulation of cell substrate adhesionGO:001081010.093
muscle cell cellular homeostasisGO:004671650.093
divalent metal ion transportGO:0070838200.093
kidney developmentGO:0001822920.092
regulation of cardiac muscle tissue developmentGO:005502410.092
nerve developmentGO:0021675450.091
myotube differentiationGO:0014902450.091
regulation of metal ion transportGO:001095940.090
rna metabolic processGO:00160702190.088
localization of cellGO:00516742440.088
biological adhesionGO:0022610400.087
muscle organ morphogenesisGO:004864480.086
heterocycle metabolic processGO:00464832900.086
ribose phosphate metabolic processGO:0019693270.085
inorganic cation transmembrane transportGO:0098662500.085
muscle tissue developmentGO:00605371100.083
cellular localizationGO:0051641970.082
regulation of transporter activityGO:003240920.082
organic cyclic compound metabolic processGO:19013603010.081
regulation of nucleobase containing compound metabolic processGO:00192192500.080
negative regulation of signal transductionGO:0009968940.079
regulation of localizationGO:00328791040.079
organic substance biosynthetic processGO:19015762890.079
nucleobase containing compound metabolic processGO:00061392740.079
regulation of myotube differentiationGO:001083020.078
developmental growthGO:00485891660.078
forebrain midbrain boundary formationGO:002190510.077
nucleoside monophosphate catabolic processGO:000912540.077
biosynthetic processGO:00090582940.077
positive regulation of dna templated transcription elongationGO:003278610.076
regulation of anatomical structure sizeGO:0090066330.076
regulation of neurogenesisGO:0050767870.075
positive regulation of muscle organ developmentGO:004863610.074
multi organism processGO:00517041340.074
regulation of heart growthGO:006042020.072
neurological system processGO:0050877620.072
positive regulation of cytosolic calcium ion concentrationGO:000720440.072
carbohydrate derivative metabolic processGO:1901135610.071
cellular response to unfolded proteinGO:003462020.070
hematopoietic or lymphoid organ developmentGO:00485341910.070
myeloid cell homeostasisGO:0002262560.069
regulation of nervous system developmentGO:0051960900.069
regulation of nucleoside metabolic processGO:000911820.069
response to drugGO:004249330.069
phosphate containing compound metabolic processGO:00067961080.069
regulation of ion transmembrane transportGO:0034765180.069
syncytium formationGO:0006949120.068
cytokinesisGO:000091030.067
neuromuscular synaptic transmissionGO:000727420.066
cell projection assemblyGO:0030031640.063
negative regulation of cell projection organizationGO:003134590.063
nitric oxide metabolic processGO:004620920.062
small molecule catabolic processGO:004428230.061
positive regulation of biosynthetic processGO:0009891680.061
calcium ion transmembrane transportGO:0070588130.061
intracellular signal transductionGO:0035556850.061
inorganic ion transmembrane transportGO:0098660570.061
cellular homeostasisGO:0019725260.061
regulation of intracellular signal transductionGO:1902531570.060
establishment of localization in cellGO:0051649770.059
membrane repolarizationGO:008600920.058
cellular macromolecular complex assemblyGO:0034622240.058
regulation of synapse assemblyGO:005196330.058
eye developmentGO:00016542770.057
regulation of primary metabolic processGO:00800903110.057
regulation of developmental processGO:00507932470.057
atrioventricular valve formationGO:000319030.056
purine ribonucleoside monophosphate catabolic processGO:000916940.056
ovulation cycleGO:004269820.056
atrial cardiac muscle cell developmentGO:005501440.056
regulation of gene expressionGO:00104682650.056
regulation of cell shapeGO:000836010.055
hematopoietic progenitor cell differentiationGO:0002244230.055
positive regulation of molecular functionGO:0044093330.055
regulation of phosphorus metabolic processGO:0051174430.055
hemopoiesisGO:00300971830.055
negative regulation of biological processGO:00485193040.054
positive regulation of cellular catabolic processGO:003133130.054
regulation of cytoskeleton organizationGO:0051493110.054
regulation of axonogenesisGO:0050770320.054
chemical homeostasisGO:0048878490.054
regulation of neuron differentiationGO:0045664560.053
ion homeostasisGO:0050801410.053
growth plate cartilage developmentGO:000341720.053
cardiac atrium developmentGO:000323040.052
establishment of apical basal cell polarityGO:003508920.052
regulation of rna metabolic processGO:00512522240.051
cellular protein complex assemblyGO:0043623190.051
regulation of signal transductionGO:00099662250.051
cell deathGO:00082191210.050
reproductionGO:0000003400.050
cartilage morphogenesisGO:0060536130.050
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.050
regulation of cellular component sizeGO:0032535300.050
regulation of protein complex assemblyGO:004325430.050
divalent inorganic cation homeostasisGO:0072507220.049
dendrite guidanceGO:007098300.049
negative regulation of response to stimulusGO:00485851040.048
cation transportGO:0006812810.048
regulation of catalytic activityGO:0050790550.048
regulation of transportGO:0051049450.048
single organism transportGO:00447652060.047
single organism nuclear importGO:190259330.047
appendage developmentGO:0048736800.047
atrial ventricular junction remodelingGO:000329420.047
nucleic acid templated transcriptionGO:00976591810.047
negative regulation of cellular processGO:00485232830.046
nucleotide metabolic processGO:0009117280.046
regulation of protein bindingGO:004339330.046
enzyme linked receptor protein signaling pathwayGO:00071671060.046
maintenance of locationGO:005123540.046
cellular response to hormone stimulusGO:0032870390.045
carboxylic acid catabolic processGO:004639530.044
striated muscle contractionGO:0006941120.044
regulation of purine nucleotide catabolic processGO:003312120.044
rna localizationGO:000640340.044
regulation of cell deathGO:00109411030.044
fatty acid beta oxidationGO:000663510.044
organic cyclic compound biosynthetic processGO:19013622230.043
diencephalon developmentGO:0021536580.043
regulation of skeletal muscle tissue developmentGO:004864140.043
cell proliferation involved in heart morphogenesisGO:006132320.043
negative regulation of cellular component organizationGO:0051129160.043
multicellular organism reproductionGO:0032504350.043
positive regulation of cell differentiationGO:0045597300.042
axonal fasciculationGO:0007413110.042
regulation of neuron projection developmentGO:0010975400.041
female gonad developmentGO:000858540.041
sensory system developmentGO:0048880760.041
programmed cell deathGO:00125011190.040
establishment of protein localization to organelleGO:007259440.039
neuron recognitionGO:0008038180.038
protein metabolic processGO:00195381830.038
neuron projection guidanceGO:0097485860.038
purine ribonucleotide metabolic processGO:0009150270.038
cardiac muscle contractionGO:006004860.038
negative regulation of signalingGO:0023057960.038
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.038
regulation of transcription dna templatedGO:00063552130.038
cellular divalent inorganic cation homeostasisGO:0072503130.038
macromolecule modificationGO:00434121110.037
regulation of epithelial cell proliferationGO:005067830.037
connective tissue developmentGO:0061448990.037
septum transversum developmentGO:000334340.037
positive regulation of striated muscle tissue developmentGO:004584410.037
cardiac myofibril assemblyGO:005500390.037
regulation of behaviorGO:0050795240.037
developmental growth involved in morphogenesisGO:0060560860.037
cognitionGO:005089010.037
embryonic hemopoiesisGO:0035162530.036
regulation of apoptotic processGO:0042981980.035
organ growthGO:0035265120.035
fatty acid catabolic processGO:000906210.035
positive regulation of neurogenesisGO:0050769240.035
macromolecule localizationGO:0033036540.035
muscle cell fate commitmentGO:004269390.035
cellular calcium ion homeostasisGO:0006874130.035
female gamete generationGO:0007292140.035
axon guidanceGO:0007411860.035
embryonic organ morphogenesisGO:00485622740.035
single organism metabolic processGO:00447102170.034
myotube cell developmentGO:0014904350.034
response to external biotic stimulusGO:0043207970.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
negative regulation of apoptotic processGO:0043066550.032
axon extensionGO:0048675450.032
regulation of ion transmembrane transporter activityGO:003241220.032
negative regulation of cell deathGO:0060548600.032
protein complex assemblyGO:0006461300.032
regulation of molecular functionGO:0065009700.032
response to endogenous stimulusGO:0009719830.032
central nervous system neuron differentiationGO:0021953740.032
regulation of blood vessel sizeGO:005088020.032
skeletal muscle myosin thick filament assemblyGO:003024150.032
cell migration involved in heart developmentGO:0060973220.031
protein complex biogenesisGO:0070271300.031
nucleobase containing small molecule metabolic processGO:0055086320.031
calcium ion transportGO:0006816180.031
hematopoietic stem cell differentiationGO:0060218200.031
digestive tract developmentGO:00485652650.031
calcium ion transport into cytosolGO:006040230.031
neural crest cell differentiationGO:0014033720.030
aromatic compound biosynthetic processGO:00194382170.030
cellular catabolic processGO:0044248270.030
cardiac ventricle developmentGO:000323190.030
nucleocytoplasmic transportGO:000691340.029
cellular metal ion homeostasisGO:0006875160.029
regulation of cellular metabolic processGO:00313233200.029
regulation of membrane potentialGO:0042391230.029
phosphorylationGO:0016310690.028
multi organism reproductive processGO:0044703360.028
mesenchyme developmentGO:00604851270.028
regulation of phosphate metabolic processGO:0019220430.028
nuclear importGO:005117030.028
digestive tract morphogenesisGO:00485462310.028
positive regulation of cell activationGO:005086710.027
regulation of calcium ion transportGO:005192420.027
protein importGO:001703830.027
regulation of hematopoietic progenitor cell differentiationGO:190153210.027
negative regulation of stem cell differentiationGO:200073720.027
organic acid metabolic processGO:0006082310.026
negative regulation of axon extension involved in axon guidanceGO:004884310.026
oxoacid metabolic processGO:0043436310.026
positive regulation of biological processGO:00485182530.026
intracellular transportGO:0046907320.026
positive regulation of cellular biosynthetic processGO:0031328680.026
lipid catabolic processGO:001604240.026
positive regulation of phosphorus metabolic processGO:0010562210.026
regulation of cell differentiationGO:00455951420.026
lamellipodium assemblyGO:003003210.026
response to abiotic stimulusGO:00096281220.026
positive regulation of muscle tissue developmentGO:190186310.026
organophosphate metabolic processGO:0019637370.025
nucleobase containing compound biosynthetic processGO:00346542050.025
metal ion transportGO:0030001580.025
catabolic processGO:0009056320.025
transcription elongation from rna polymerase ii promoterGO:000636830.025
mesenchymal cell developmentGO:0014031780.025
nuclear transportGO:005116940.025
regulation of cardiac muscle contractionGO:005511720.025
apoptotic processGO:00069151160.025
positive regulation of metabolic processGO:00098931080.025
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.025
cartilage developmentGO:0051216960.024
digestive system developmentGO:00551232890.024
regulation of cell projection assemblyGO:006049140.024
pectoral fin developmentGO:0033339500.024
heart valve morphogenesisGO:000317980.024
lamellipodium organizationGO:009758110.024
branching morphogenesis of an epithelial tubeGO:0048754150.024
response to woundingGO:00096111160.024
atp metabolic processGO:004603450.023
regulation of nucleotide catabolic processGO:003081120.023
single organism cellular localizationGO:1902580460.023
cellular cation homeostasisGO:0030003170.023
cellular response to organic substanceGO:00713101050.023
embryonic neurocranium morphogenesisGO:0048702150.023
endocardial cushion morphogenesisGO:000320330.023
platelet formationGO:003022010.023
nephron tubule epithelial cell differentiationGO:007216010.022
mitotic cell cycleGO:0000278640.022
locomotory behaviorGO:0007626340.022
regulation of mechanoreceptor differentiationGO:004563110.022
erythrocyte developmentGO:0048821240.022
protein targeting to nucleusGO:004474430.022
regulation of dendrite developmentGO:005077330.022
positive regulation of rna metabolic processGO:0051254590.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
regulation of nitric oxide mediated signal transductionGO:001074910.021
nucleoside phosphate metabolic processGO:0006753280.021
mitochondrion organizationGO:000700540.021
establishment of monopolar cell polarityGO:006116220.021
embryonic skeletal system morphogenesisGO:0048704930.021
cellular macromolecule metabolic processGO:00442603910.020
vesicle mediated transportGO:0016192220.020
embryonic heart tube left right pattern formationGO:006097150.020
cellular response to fluid shear stressGO:007149810.020
divalent inorganic cation transportGO:0072511210.020
heart valve developmentGO:0003170140.020
regulation of cellular component movementGO:0051270550.020
negative regulation of heart contractionGO:004582220.020
olfactory bulb developmentGO:002177240.020
spinal cord developmentGO:0021510460.019
endocytosisGO:0006897160.019
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.019
multicellular organismal reproductive processGO:0048609350.019
regulation of bone mineralizationGO:003050020.019
purine containing compound metabolic processGO:0072521290.019
positive regulation of cell projection organizationGO:003134690.019
regulation of growthGO:0040008420.019
purine nucleotide metabolic processGO:0006163270.018
positive regulation of response to stimulusGO:0048584800.018
cell cycleGO:0007049930.018

ttna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.333
cardiomyopathyDOID:005070000.325
heart diseaseDOID:11400.325
muscular diseaseDOID:008000000.325
cardiovascular system diseaseDOID:128700.325
musculoskeletal system diseaseDOID:1700.325
muscle tissue diseaseDOID:6600.325
myopathyDOID:42300.325
intrinsic cardiomyopathyDOID:006003600.072
dilated cardiomyopathyDOID:1293000.029