Danio rerio

0 known processes

LOC557072

caspase recruitment domain-containing protein 11-like

LOC557072 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.733
antimicrobial humoral responseGO:001973020.688
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.526
defense response to other organismGO:0098542330.523
regulation of innate immune responseGO:0045088110.522
positive regulation of erk1 and erk2 cascadeGO:007037420.510
regulation of erk1 and erk2 cascadeGO:007037240.496
positive regulation of innate immune responseGO:004508980.484
regulation of epithelial cell proliferationGO:005067830.449
activation of immune responseGO:000225390.426
defense response to bacteriumGO:0042742220.413
humoral immune response mediated by circulating immunoglobulinGO:000245530.405
defense responseGO:0006952470.403
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.383
cellular macromolecule biosynthetic processGO:00346452240.383
regulation of cytokine productionGO:000181730.382
rna biosynthetic processGO:00327741810.375
response to bacteriumGO:0009617580.351
phagocytosisGO:000690930.328
cell migrationGO:00164772370.310
cellular response to molecule of bacterial originGO:007121930.310
cellular nitrogen compound biosynthetic processGO:00442712180.307
response to stressGO:00069502630.290
positive regulation of lymphocyte mediated immunityGO:000270810.283
positive regulation of i kappab kinase nf kappab signalingGO:004312330.277
peptide metabolic processGO:000651810.265
response to other organismGO:0051707970.263
innate immune response activating signal transductionGO:000275850.258
regulation of protein transportGO:005122330.253
production of molecular mediator of immune responseGO:000244020.249
positive regulation of defense response to virus by hostGO:000223000.237
antibacterial humoral responseGO:001973120.221
positive regulation of cytokine productionGO:000181920.221
positive regulation of stress activated mapk cascadeGO:003287430.217
response to external biotic stimulusGO:0043207970.213
symbiosis encompassing mutualism through parasitismGO:004440340.212
response to dsrnaGO:004333170.212
positive regulation of protein kinase b signalingGO:005189710.210
regulation of protein modification by small protein conjugation or removalGO:190332030.204
negative regulation of cytokine productionGO:000181810.190
cellular response to chemical stimulusGO:00708871570.188
regulation of sequence specific dna binding transcription factor activityGO:005109090.188
immunoglobulin productionGO:000237710.180
protein secretionGO:000930610.177
positive regulation of jnk cascadeGO:004633030.175
positive regulation of defense responseGO:003134990.170
regulation of inflammatory responseGO:005072720.169
regulation of biological qualityGO:00650082630.169
positive regulation of secretion by cellGO:190353210.166
regulation of i kappab kinase nf kappab signalingGO:004312240.157
response to woundingGO:00096111160.157
positive regulation of lipid metabolic processGO:004583410.155
interferon beta productionGO:003260810.154
cellular amine metabolic processGO:004410620.153
positive regulation of leukocyte mediated immunityGO:000270510.152
humoral immune responseGO:000695950.147
regulation of protein ubiquitinationGO:003139630.146
regulation of interferon beta productionGO:003264810.144
positive regulation of transportGO:005105020.144
regulation of gene expressionGO:00104682650.138
response to external stimulusGO:00096052640.137
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.135
amide biosynthetic processGO:004360410.134
positive regulation of inflammatory responseGO:005072910.133
regulation of cellular amine metabolic processGO:003323800.130
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.130
nucleic acid metabolic processGO:00903042440.124
regulation of biosynthetic processGO:00098892500.116
amine metabolic processGO:000930820.115
regulation of cellular ketone metabolic processGO:001056570.112
signal transductionGO:00071654550.108
organic cyclic compound biosynthetic processGO:19013622230.106
response to lipopolysaccharideGO:0032496130.104
positive regulation of cellular amine metabolic processGO:003324000.101
regulation of cellular biosynthetic processGO:00313262450.101
regulation of cysteine type endopeptidase activityGO:2000116210.101
response to molecule of bacterial originGO:0002237140.100
regulation of defense responseGO:0031347140.100
regulation of establishment of protein localizationGO:007020140.096
larval developmentGO:000216420.095
nucleic acid templated transcriptionGO:00976591810.095
regulation of immune responseGO:0050776140.094
activation of innate immune responseGO:000221860.094
regulation of immune effector processGO:000269750.094
regulation of peptidyl tyrosine phosphorylationGO:005073010.094
defense response to gram positive bacteriumGO:005083060.094
response to biotic stimulusGO:0009607970.092
macromolecule glycosylationGO:004341390.091
myeloid cell differentiationGO:0030099860.087
cellular amino acid metabolic processGO:000652070.086
regulation of cell communicationGO:00106462320.086
adaptive immune responseGO:000225050.085
response to exogenous dsrnaGO:004333060.085
positive regulation of immune responseGO:0050778110.084
cellular response to lipopolysaccharideGO:007122230.082
immune response regulating signaling pathwayGO:000276450.082
regulation of response to biotic stimulusGO:000283120.081
biosynthetic processGO:00090582940.081
membrane lipid biosynthetic processGO:004646720.078
nitrogen compound metabolic processGO:00068073190.076
response to chemicalGO:00422213200.074
positive regulation of notch signaling pathwayGO:004574730.074
positive regulation of epithelial cell proliferationGO:005067910.073
regulation of transcription dna templatedGO:00063552130.072
erk1 and erk2 cascadeGO:007037140.072
reactive oxygen species biosynthetic processGO:190340910.071
regulation of programmed cell deathGO:00430671010.070
immune response activating signal transductionGO:000275750.069
multi organism processGO:00517041340.069
single organism metabolic processGO:00447102170.068
i kappab kinase nf kappab signalingGO:000724940.068
macromolecule biosynthetic processGO:00090592270.067
positive regulation of secretionGO:005104710.065
regulation of rna biosynthetic processGO:20011412130.065
glycoprotein metabolic processGO:0009100230.064
hemopoiesisGO:00300971830.064
defense response to gram negative bacteriumGO:005082980.064
locomotionGO:00400113130.063
glycolipid biosynthetic processGO:000924710.062
cellular response to biotic stimulusGO:007121630.062
cellular amide metabolic processGO:004360340.062
cellular ketone metabolic processGO:0042180110.061
cellular nitrogen compound metabolic processGO:00346412900.061
negative regulation of cell communicationGO:0010648960.060
response to lipidGO:0033993600.060
innate immune responseGO:0045087130.060
regulation of response to stressGO:0080134360.060
erythrocyte differentiationGO:0030218540.059
regulation of defense response to virus by hostGO:005069110.058
negative regulation of signalingGO:0023057960.057
morphogenesis of an epitheliumGO:00020093330.057
immunoglobulin mediated immune responseGO:001606430.057
regulation of notch signaling pathwayGO:0008593160.056
cellular protein catabolic processGO:004425740.056
b cell mediated immunityGO:001972430.055
positive regulation of cellular processGO:00485222010.055
regulation of type i interferon productionGO:003247920.055
glycosphingolipid biosynthetic processGO:000668810.054
cellular response to organonitrogen compoundGO:007141750.054
organic cyclic compound metabolic processGO:19013603010.054
positive regulation of map kinase activityGO:004340630.053
regulation of multicellular organismal processGO:00512392770.053
cellular aromatic compound metabolic processGO:00067252950.053
positive regulation of response to external stimulusGO:003210390.052
cellular response to stressGO:0033554620.052
compound eye developmentGO:004874920.052
regulation of vesicle mediated transportGO:006062790.052
transcription dna templatedGO:00063511810.052
lymphocyte mediated immunityGO:000244950.051
regulation of nucleobase containing compound metabolic processGO:00192192500.051
oxoacid metabolic processGO:0043436310.050
regulation of striated muscle contractionGO:000694220.050
carboxylic acid metabolic processGO:0019752220.050
stem cell maintenanceGO:001982740.050
regulation of rna metabolic processGO:00512522240.049
regulation of cell motilityGO:2000145460.048
heterocycle biosynthetic processGO:00181302150.048
regulation of cellular amino acid metabolic processGO:000652100.047
cell surface receptor signaling pathwayGO:00071663250.047
regulation of macromolecule biosynthetic processGO:00105562250.047
vasculature developmentGO:00019442780.047
localization of cellGO:00516742440.046
heterocycle metabolic processGO:00464832900.046
regulation of nitrogen compound metabolic processGO:00511712510.046
tube morphogenesisGO:00352393490.046
leukocyte differentiationGO:0002521250.046
regulation of primary metabolic processGO:00800903110.046
positive regulation of cellular amino acid metabolic processGO:004576400.046
apoptotic processGO:00069151160.046
cellular response to endogenous stimulusGO:0071495680.046
regulation of cellular component organizationGO:0051128860.046
cell motilityGO:00488702440.045
regulation of cellular metabolic processGO:00313233200.045
neutrophil chemotaxisGO:0030593100.045
somatic stem cell maintenanceGO:003501910.045
positive regulation of cell cycleGO:004578730.045
response to organic substanceGO:00100331530.045
cellular response to organic substanceGO:00713101050.044
negative regulation of biological processGO:00485193040.044
nucleobase containing compound biosynthetic processGO:00346542050.044
tissue regenerationGO:0042246740.043
erythrocyte homeostasisGO:0034101550.043
camera type eye morphogenesisGO:00485931080.043
cellular biosynthetic processGO:00442492860.042
homeostatic processGO:00425921420.042
intracellular signal transductionGO:0035556850.041
organonitrogen compound metabolic processGO:1901564740.041
positive regulation of macromolecule biosynthetic processGO:0010557590.041
ganglioside metabolic processGO:000157330.040
posterior lateral line system developmentGO:0048915460.040
immune effector processGO:0002252230.040
endocardium morphogenesisGO:000316040.039
maintenance of locationGO:005123540.038
immune system processGO:00023762410.038
lipid metabolic processGO:0006629520.038
regulation of cellular component movementGO:0051270550.037
neutrophil migrationGO:1990266100.037
cognitionGO:005089010.037
apoptotic process involved in developmentGO:190274220.037
positive regulation of multicellular organismal processGO:0051240520.037
positive regulation of biological processGO:00485182530.036
skeletal muscle organ developmentGO:0060538780.036
interspecies interaction between organismsGO:004441940.036
eye developmentGO:00016542770.036
autophagyGO:000691440.036
heart morphogenesisGO:00030071560.036
cellular lipid metabolic processGO:0044255360.035
positive regulation of immune effector processGO:000269930.035
regulation of rho protein signal transductionGO:003502320.035
cellular response to oxygen levelsGO:007145310.035
regulation of metabolic processGO:00192223590.035
g1 s transition of mitotic cell cycleGO:000008210.035
hormone metabolic processGO:0042445190.034
response to corticosteroidGO:003196010.034
regulation of granulocyte chemotaxisGO:007162260.033
gtp catabolic processGO:000618420.033
regulation of locomotionGO:0040012550.033
dna biosynthetic processGO:007189730.033
posterior lateral line neuromast developmentGO:0048919200.033
regulation of actin filament based processGO:003297090.032
negative regulation of defense responseGO:003134820.032
digestive tract morphogenesisGO:00485462310.032
activation of mapk activityGO:000018730.032
convergent extensionGO:00600261180.032
regulation of leukocyte mediated immunityGO:000270310.031
mononuclear cell proliferationGO:003294310.031
regulation of response to cytokine stimulusGO:006075930.031
leukocyte migrationGO:0050900150.031
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.030
chordate embryonic developmentGO:00430092710.030
astrocyte differentiationGO:004870810.030
cellular component movementGO:00069283350.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
regulation of signal transductionGO:00099662250.030
cellular macromolecule metabolic processGO:00442603910.030
aromatic compound biosynthetic processGO:00194382170.030
cell cycle g1 s phase transitionGO:004484310.029
regulation of production of molecular mediator of immune responseGO:000270010.029
organic acid metabolic processGO:0006082310.029
stem cell divisionGO:001714510.029
defense response to virusGO:0051607100.029
response to uvGO:000941130.029
regulation of growth rateGO:004000910.029
appendage developmentGO:0048736800.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.028
nerve developmentGO:0021675450.028
positive regulation of cellular metabolic processGO:0031325940.028
organic substance biosynthetic processGO:19015762890.028
regulation of sarcomere organizationGO:006029720.027
negative regulation of apoptotic processGO:0043066550.027
digestive system developmentGO:00551232890.027
regulation of signalingGO:00230512350.027
muscle organ developmentGO:00075171010.027
germ line stem cell maintenanceGO:003071820.027
regulation of multicellular organism growthGO:004001440.027
regenerationGO:0031099910.026
eye morphogenesisGO:00485921440.026
muscle fiber developmentGO:0048747520.026
regulation of muscle contractionGO:000693730.026
purine ribonucleoside monophosphate catabolic processGO:000916940.026
multicellular organism growthGO:003526440.026
organic anion transportGO:0015711150.026
regulation of protein localization to nucleusGO:190018020.026
specification of symmetryGO:00097992040.026
periodic partitioningGO:000736510.025
cellular response to hypoxiaGO:007145610.025
rna metabolic processGO:00160702190.025
skeletal system developmentGO:00015011810.025
regulation of dna replicationGO:000627530.025
estrogen metabolic processGO:000821020.025
enzyme linked receptor protein signaling pathwayGO:00071671060.025
muscle tissue developmentGO:00605371100.025
cellular response to oxygen containing compoundGO:1901701200.024
regulation of autophagyGO:001050630.024
circulatory system processGO:0003013870.024
protein targeting to nucleusGO:004474430.024
gastrulationGO:00073692080.024
epithelial tube morphogenesisGO:00605621480.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
system processGO:00030081850.024
regulation of heart growthGO:006042020.024
mitochondrion organizationGO:000700540.024
rho protein signal transductionGO:000726650.024
negative regulation of cell deathGO:0060548600.024
regulation of nucleocytoplasmic transportGO:004682220.024
myeloid cell homeostasisGO:0002262560.024
neuron developmentGO:00486662620.024
nucleic acid transportGO:005065720.023
segment polarity determinationGO:000736710.023
regulation of behaviorGO:0050795240.023
ameboidal type cell migrationGO:00016671430.023
response to drugGO:004249330.023
protein metabolic processGO:00195381830.023
negative regulation of cellular processGO:00485232830.023
muscle structure developmentGO:00610611960.022
heart developmentGO:00075073130.022
regulation of glial cell differentiationGO:004568540.022
inositol lipid mediated signalingGO:004801720.022
regulation of protein complex assemblyGO:004325430.022
response to organonitrogen compoundGO:0010243120.022
positive regulation of cell activationGO:005086710.022
pattern recognition receptor signaling pathwayGO:000222150.022
regulation of transmembrane transportGO:0034762180.022
embryonic hemopoiesisGO:0035162530.021
epithelial cell morphogenesisGO:000338220.021
positive regulation of production of molecular mediator of immune responseGO:000270210.021
inflammatory responseGO:000695480.021
peptide transportGO:001583310.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
negative regulation of programmed cell deathGO:0043069580.021
brain developmentGO:00074202930.021
anterior posterior pattern specificationGO:00099521520.021
organonitrogen compound biosynthetic processGO:1901566470.021
cytoskeleton organizationGO:0007010960.021
tissue remodelingGO:004877140.021
regulation of phosphorus metabolic processGO:0051174430.021
positive regulation of cellular component biogenesisGO:004408930.020
regulation of chemotaxisGO:0050920180.020
regulation of cell deathGO:00109411030.020
regulation of protein targetingGO:190353320.020
cranial nerve developmentGO:0021545420.020
regulation of response to stimulusGO:00485832690.020
actin filament polymerizationGO:003004120.020
morphogenesis of an epithelial foldGO:006057110.020
stem cell fate commitmentGO:004886510.020
regulation of nucleoside metabolic processGO:000911820.020
zymogen activationGO:003163830.020
membrane invaginationGO:001032410.020
phosphorylationGO:0016310690.020
central nervous system developmentGO:00074173870.020
regulation of purine nucleotide catabolic processGO:003312120.020
response to endogenous stimulusGO:0009719830.020
actin filament based processGO:0030029640.020
positive regulation of cell communicationGO:0010647560.020
mitotic metaphase plate congressionGO:000708010.020
regulation of rac protein signal transductionGO:003502010.020
striated muscle tissue developmentGO:00147061100.020
head developmentGO:00603223030.019
response to oxygen containing compoundGO:1901700550.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
regulation of multicellular organismal developmentGO:20000262230.019
embryo development ending in birth or egg hatchingGO:00097922710.019
positive regulation of multi organism processGO:004390230.019
gtp metabolic processGO:004603940.019
pteridine containing compound metabolic processGO:004255830.019
negative regulation of protein phosphorylationGO:000193340.019
cellular response to nutrient levelsGO:003166920.019
heart contractionGO:0060047710.018
negative regulation of immune system processGO:000268370.018
granulocyte migrationGO:0097530110.018
nucleoside monophosphate catabolic processGO:000912540.018
cellular protein metabolic processGO:00442671290.018
monocyte differentiationGO:003022420.018
rna transportGO:005065820.018
purine nucleoside monophosphate catabolic processGO:000912840.018
regulation of intracellular protein transportGO:003315730.018
fin morphogenesisGO:0033334530.018
protein polymerizationGO:005125840.018
regulation of metal ion transportGO:001095940.018
positive regulation of dna metabolic processGO:005105410.018
nucleobase containing compound metabolic processGO:00061392740.018
regulation of cytokine mediated signaling pathwayGO:000195930.018
regulation of molecular functionGO:0065009700.018
immune system developmentGO:00025201910.017
regulation of reproductive processGO:200024140.017
regulation of defense response to virusGO:005068820.017
epithelial cell differentiationGO:00308551160.017
regulation of organ growthGO:004662030.017
macromolecule modificationGO:00434121110.017
regulation of cell activationGO:005086510.017
positive regulation of signalingGO:0023056560.017
negative regulation of rna biosynthetic processGO:1902679450.017
sialylationGO:009750340.017
regulation of mitochondrion organizationGO:001082110.017
blood vessel developmentGO:00015682460.017
epithelial cell proliferationGO:0050673170.017
blood circulationGO:0008015870.017
cartilage developmentGO:0051216960.017
notochord developmentGO:0030903540.017
digestive tract developmentGO:00485652650.017
negative regulation of i kappab kinase nf kappab signalingGO:004312410.017
regulation of jnk cascadeGO:004632850.017
response to peptideGO:190165260.017
mechanoreceptor differentiationGO:0042490370.016
fin developmentGO:0033333770.016
posterior lateral line nerve glial cell developmentGO:004894150.016
mapk cascadeGO:0000165180.016
guanosine containing compound catabolic processGO:190106920.016
membrane lipid metabolic processGO:0006643100.016
response to vitaminGO:003327330.016
regulation of nucleotide catabolic processGO:003081120.016
regulation of protein import into nucleusGO:004230620.016
single organism nuclear importGO:190259330.016
heart loopingGO:0001947940.016
regulation of protein metabolic processGO:0051246560.016
heart processGO:0003015710.016
regulation of macromolecule metabolic processGO:00602553170.016
cell chemotaxisGO:0060326170.016
regulation of skeletal muscle fiber developmentGO:004874220.016
regulation of actin filament based movementGO:190311510.016
regulation of endothelial cell differentiationGO:004560130.016
phagocytosis engulfmentGO:000691110.015
negative regulation of protein kinase activityGO:000646940.015
t cell mediated immunityGO:000245610.015
embryonic organ developmentGO:00485683810.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
cellular component disassemblyGO:002241110.015
sphingolipid biosynthetic processGO:003014820.015
muscle cell differentiationGO:00426921390.015
leukocyte chemotaxisGO:0030595120.015
regulation of oligodendrocyte differentiationGO:004871310.015
protein localization to nucleusGO:003450430.015
camera type eye developmentGO:00430102220.015
erythrocyte maturationGO:004324980.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of localizationGO:00328791040.015
cardiac muscle cell contractionGO:008600310.015
immune responseGO:0006955280.015
cytokine metabolic processGO:004210710.015
nephron tubule morphogenesisGO:007207810.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
response to organic cyclic compoundGO:0014070510.015
oocyte maturationGO:000155640.015
peptidyl tyrosine phosphorylationGO:001810850.015
response to antibioticGO:004667710.015
liver developmentGO:0001889960.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
sensory organ developmentGO:00074233930.014
macromolecule localizationGO:0033036540.014
single organism localizationGO:19025782250.014
glial cell fate determinationGO:000740310.014
ribonucleoside monophosphate catabolic processGO:000915840.014
myeloid cell developmentGO:0061515320.014
cellular protein modification processGO:00064641000.014
mechanosensory lateral line system developmentGO:0048881490.014
pectoral fin developmentGO:0033339500.014
regulation of mapk cascadeGO:0043408140.014
germ line stem cell divisionGO:004207810.014
protein modification processGO:00362111000.014
exocytosisGO:000688710.014
positive regulation of chromatin modificationGO:190331010.014
cellular response to external stimulusGO:007149620.014
positive regulation of chromosome organizationGO:200125210.014
chemotaxisGO:00069351040.014
cell cycle g2 m phase transitionGO:004483940.013
inner ear developmentGO:00488391260.013
establishment of rna localizationGO:005123630.013
negative regulation of nf kappab transcription factor activityGO:003208810.013
response to alkaloidGO:004327920.013
regulation of bindingGO:005109830.013
cell recognitionGO:0008037190.013
gene expressionGO:00104672520.013
positive regulation of muscle tissue developmentGO:190186310.013
neuroblast fate commitmentGO:001401710.013
regulation of cellular response to stressGO:0080135200.013
negative regulation of growth rateGO:004596710.013
protein ubiquitinationGO:0016567110.013
negative regulation of molecular functionGO:0044092230.013
protein acylationGO:004354330.013
establishment of protein localization to organelleGO:007259440.013
lateral line system developmentGO:0048925760.013
cellular response to growth factor stimulusGO:0071363390.013
myotube cell developmentGO:0014904350.013
negative regulation of multicellular organismal processGO:0051241690.013
neuromast developmentGO:0048884460.013
protein phosphorylationGO:0006468470.013
negative regulation of leukocyte differentiationGO:190210610.013
regulation of gtpase activityGO:004308720.013
connective tissue developmentGO:0061448990.013
cellular response to fatty acidGO:007139830.013
hard palate developmentGO:006002240.013
growth plate cartilage morphogenesisGO:000342210.013
peptidyl serine phosphorylationGO:001810510.012
determination of bilateral symmetryGO:00098552040.012
positive regulation of gliogenesisGO:001401520.012
glucose importGO:004632320.012
determination of heart left right asymmetryGO:00613711170.012
retina development in camera type eyeGO:00600411460.012
regulation of cytokine biosynthetic processGO:004203510.012
protein importGO:001703830.012
ear developmentGO:00435831270.012
detection of chemical stimulusGO:000959340.012
cellular response to xenobiotic stimulusGO:0071466350.012
organelle fusionGO:004828430.012
granulocyte chemotaxisGO:0071621110.012
embryonic organ morphogenesisGO:00485622740.012
cellular modified amino acid metabolic processGO:000657530.012
phosphate containing compound metabolic processGO:00067961080.012

LOC557072 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
musculoskeletal system diseaseDOID:1700.022
cardiovascular system diseaseDOID:128700.016
myopathyDOID:42300.016
cardiomyopathyDOID:005070000.016
muscle tissue diseaseDOID:6600.016
heart diseaseDOID:11400.016
muscular diseaseDOID:008000000.016
disease of cellular proliferationDOID:1456600.012