Danio rerio

0 known processes

hpse2

heparanase 2

(Aliases: si:dkeyp-22h2.2)

hpse2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.090
cellular protein catabolic processGO:004425740.080
maintenance of locationGO:005123540.071
biosynthetic processGO:00090582940.066
cellular macromolecule biosynthetic processGO:00346452240.065
agingGO:000756820.060
organic cyclic compound biosynthetic processGO:19013622230.059
nucleic acid metabolic processGO:00903042440.058
regulation of neural precursor cell proliferationGO:200017730.053
organic substance biosynthetic processGO:19015762890.051
regulation of nitrogen compound metabolic processGO:00511712510.048
cell surface receptor signaling pathwayGO:00071663250.046
regulation of cellular metabolic processGO:00313233200.046
nitrogen compound metabolic processGO:00068073190.046
stem cell maintenanceGO:001982740.045
organic cyclic compound metabolic processGO:19013603010.045
lipid storageGO:001991510.045
ribonucleotide biosynthetic processGO:0009260200.044
regulation of multicellular organism growthGO:004001440.044
signal transductionGO:00071654550.044
positive regulation of cell cycleGO:004578730.043
positive regulation of transportGO:005105020.043
internal peptidyl lysine acetylationGO:001839320.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.043
regulation of biosynthetic processGO:00098892500.042
cellular biosynthetic processGO:00442492860.042
phagocytosisGO:000690930.041
ubiquitin dependent protein catabolic processGO:000651130.041
heterocycle metabolic processGO:00464832900.040
cell projection morphogenesisGO:00488582440.039
establishment of protein localization to organelleGO:007259440.038
multicellular organism growthGO:003526440.037
regulation of protein targetingGO:190353320.037
nucleobase containing compound metabolic processGO:00061392740.037
regulation of metabolic processGO:00192223590.037
regulation of stem cell proliferationGO:007209120.037
cellular aromatic compound metabolic processGO:00067252950.037
regulation of dna replicationGO:000627530.036
regulation of cellular amine metabolic processGO:003323800.036
cellular macromolecule metabolic processGO:00442603910.036
positive regulation of cellular component biogenesisGO:004408930.034
protein acetylationGO:000647320.033
modification dependent macromolecule catabolic processGO:004363230.033
leukocyte proliferationGO:007066110.033
autophagyGO:000691440.033
proteasomal protein catabolic processGO:001049820.033
modification dependent protein catabolic processGO:001994130.033
regulation of signal transductionGO:00099662250.033
single organism metabolic processGO:00447102170.032
cellular ketone metabolic processGO:0042180110.032
protein localization to nucleusGO:003450430.032
protein import into nucleusGO:000660630.031
cellular nitrogen compound metabolic processGO:00346412900.031
head developmentGO:00603223030.031
regulation of protein complex assemblyGO:004325430.031
cellular component morphogenesisGO:00329893360.031
regulation of stem cell differentiationGO:200073640.030
hormone secretionGO:004687920.030
single organism nuclear importGO:190259330.030
macromolecule biosynthetic processGO:00090592270.030
protein targeting to nucleusGO:004474430.030
regulation of nucleobase containing compound metabolic processGO:00192192500.030
regulation of cellular biosynthetic processGO:00313262450.029
regulation of reactive oxygen species metabolic processGO:200037720.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
positive regulation of protein complex assemblyGO:003133420.029
cell morphogenesisGO:00009022890.029
regulation of signalingGO:00230512350.029
regulation of bindingGO:005109830.028
regulation of cellular amino acid metabolic processGO:000652100.028
stem cell proliferationGO:007208940.028
amine metabolic processGO:000930820.028
peptidyl lysine acetylationGO:001839420.028
regulation of protein transportGO:005122330.027
cellular response to extracellular stimulusGO:003166820.027
heterocycle biosynthetic processGO:00181302150.027
positive regulation of secretionGO:005104710.027
regulation of establishment of protein localizationGO:007020140.027
regulation of cytokine productionGO:000181730.026
protein importGO:001703830.026
carboxylic acid metabolic processGO:0019752220.026
rna metabolic processGO:00160702190.026
response to nutrientGO:000758430.026
small molecule metabolic processGO:0044281770.026
aromatic compound biosynthetic processGO:00194382170.026
protein acylationGO:004354330.026
cellular amine metabolic processGO:004410620.026
response to drugGO:004249330.025
cellular amino acid metabolic processGO:000652070.025
peptide transportGO:001583310.025
regulation of response to stimulusGO:00485832690.025
response to chemicalGO:00422213200.025
regulation of cellular ketone metabolic processGO:001056570.025
regulation of tube sizeGO:003515020.025
meiotic nuclear divisionGO:000712640.025
regulation of primary metabolic processGO:00800903110.025
nuclear importGO:005117030.025
negative regulation of catabolic processGO:000989530.025
locomotionGO:00400113130.024
regulation of blood vessel sizeGO:005088020.024
mononuclear cell proliferationGO:003294310.024
response to glucoseGO:000974930.024
regionalizationGO:00030022740.024
regulation of macromolecule metabolic processGO:00602553170.024
negative regulation of cellular catabolic processGO:003133030.024
positive regulation of secretion by cellGO:190353210.024
carboxylic acid catabolic processGO:004639530.024
regulation of hormone secretionGO:004688320.024
sensory organ developmentGO:00074233930.024
regulation of carbohydrate metabolic processGO:000610940.024
carbohydrate biosynthetic processGO:001605110.024
regulation of macromolecule biosynthetic processGO:00105562250.024
cellular protein metabolic processGO:00442671290.023
negative regulation of biological processGO:00485193040.023
regulation of protein import into nucleusGO:004230620.023
nuclear transportGO:005116940.023
hormone transportGO:000991420.023
response to external stimulusGO:00096052640.023
response to carbohydrateGO:000974330.023
cellular response to chemical stimulusGO:00708871570.023
response to woundingGO:00096111160.023
regulation of protein localization to nucleusGO:190018020.022
regulation of cell activationGO:005086510.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
cell part morphogenesisGO:00329902460.022
negative regulation of protein phosphorylationGO:000193340.022
rna biosynthetic processGO:00327741810.022
cell substrate adhesionGO:003158940.022
organic acid metabolic processGO:0006082310.022
eye developmentGO:00016542770.022
female sex differentiationGO:004666040.022
positive regulation of cell activationGO:005086710.022
response to stressGO:00069502630.022
cellular component movementGO:00069283350.022
determination of bilateral symmetryGO:00098552040.022
positive regulation of cytokine productionGO:000181920.022
regulation of autophagyGO:001050630.022
regulation of multicellular organismal processGO:00512392770.022
regulation of sodium ion transportGO:000202820.022
regulation of synaptic plasticityGO:004816710.022
organonitrogen compound metabolic processGO:1901564740.022
positive regulation of cytoskeleton organizationGO:005149530.021
nucleocytoplasmic transportGO:000691340.021
regulation of cell communicationGO:00106462320.021
neuroblast proliferationGO:000740520.021
tube morphogenesisGO:00352393490.021
negative regulation of neural precursor cell proliferationGO:200017810.021
negative regulation of sequestering of calcium ionGO:005128340.021
regulation of blood pressureGO:000821710.021
negative regulation of autophagyGO:001050710.021
positive regulation of immune effector processGO:000269930.021
lymphocyte proliferationGO:004665110.021
blood vessel developmentGO:00015682460.021
cellular response to lipopolysaccharideGO:007122230.021
morphogenesis of an epitheliumGO:00020093330.021
cellular response to starvationGO:000926710.020
angiogenesisGO:00015251580.020
regulation of rna metabolic processGO:00512522240.020
production of molecular mediator of immune responseGO:000244020.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
organic acid catabolic processGO:001605430.020
compound eye developmentGO:004874920.020
positive regulation of cellular amine metabolic processGO:003324000.020
cellular response to nutrient levelsGO:003166920.020
actin polymerization or depolymerizationGO:000815420.020
regulation of intracellular protein transportGO:003315730.020
regulation of nucleocytoplasmic transportGO:004682220.020
renal tubule morphogenesisGO:006133310.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.020
neuron differentiationGO:00301823530.020
regulation of production of molecular mediator of immune responseGO:000270010.019
transcription dna templatedGO:00063511810.019
regulation of cytoplasmic transportGO:190364940.019
digestive tract developmentGO:00485652650.019
digestive system developmentGO:00551232890.019
phosphatidylinositol 3 kinase signalingGO:001406520.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
immunoglobulin mediated immune responseGO:001606430.019
nucleobase containing compound biosynthetic processGO:00346542050.019
vasculature developmentGO:00019442780.019
blood vessel morphogenesisGO:00485142160.019
g protein coupled receptor signaling pathwayGO:0007186740.019
nucleic acid templated transcriptionGO:00976591810.019
regulation of epithelial cell proliferationGO:005067830.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
response to hexoseGO:000974630.019
cell cycle g1 s phase transitionGO:004484310.018
positive regulation of cellular catabolic processGO:003133130.018
reactive oxygen species metabolic processGO:007259360.018
sequestering of metal ionGO:005123830.018
single organism organelle organizationGO:19025891990.018
macroautophagyGO:001623610.018
cell projection organizationGO:00300302840.018
positive regulation of catabolic processGO:000989640.018
negative regulation of dna metabolic processGO:005105340.018
cell cycle arrestGO:000705010.018
regulation of meiotic cell cycleGO:005144510.017
regulation of biological qualityGO:00650082630.017
positive regulation of camp biosynthetic processGO:003081920.017
organism emergence from protective structureGO:007168440.017
peptidyl threonine phosphorylationGO:001810710.017
positive regulation of metabolic processGO:00098931080.017
response to topologically incorrect proteinGO:003596620.017
axonogenesisGO:00074091520.017
central nervous system developmentGO:00074173870.017
response to vitaminGO:003327330.017
regulation of multicellular organismal metabolic processGO:004424620.017
lateral inhibitionGO:004633110.017
extrinsic apoptotic signaling pathwayGO:009719130.017
cognitionGO:005089010.017
inositol lipid mediated signalingGO:004801720.017
positive regulation of lymphocyte mediated immunityGO:000270810.017
regulation of mrna processingGO:005068430.017
immune system developmentGO:00025201910.017
wound healingGO:0042060900.017
guanosine containing compound metabolic processGO:190106840.017
small molecule catabolic processGO:004428230.017
cellular lipid catabolic processGO:004424230.017
regulation of cell substrate adhesionGO:001081010.017
cellular component disassemblyGO:002241110.017
reactive nitrogen species metabolic processGO:200105700.016
negative chemotaxisGO:005091910.016
positive regulation of dna metabolic processGO:005105410.016
germ line stem cell maintenanceGO:003071820.016
tissue remodelingGO:004877140.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
protein secretionGO:000930610.016
cellular response to external stimulusGO:007149620.016
female gonad developmentGO:000858540.016
chemosensory behaviorGO:000763510.016
growthGO:00400071740.016
mitochondrion organizationGO:000700540.016
phosphatidylinositol mediated signalingGO:004801520.016
regulation of gene expressionGO:00104682650.016
locomotor rhythmGO:004547530.016
positive regulation of biological processGO:00485182530.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
development of primary female sexual characteristicsGO:004654540.016
adult behaviorGO:003053420.016
regulation of multicellular organismal developmentGO:20000262230.016
nitric oxide biosynthetic processGO:000680920.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
gene expressionGO:00104672520.016
positive regulation of protein kinase b signalingGO:005189710.016
nephron morphogenesisGO:007202820.016
regulation of metal ion transportGO:001095940.016
regulation of bone mineralizationGO:003050020.016
peptidyl threonine modificationGO:001821010.016
somatic stem cell maintenanceGO:003501910.016
gtp catabolic processGO:000618420.016
multicellular organismal metabolic processGO:004423620.016
b cell activationGO:004211320.016
secondary metabolic processGO:001974830.016
negative regulation of signal transductionGO:0009968940.016
kidney developmentGO:0001822920.015
negative regulation of cytokine productionGO:000181810.015
anterior posterior pattern specificationGO:00099521520.015
negative regulation of cytoplasmic transportGO:190365020.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
cellular carbohydrate metabolic processGO:004426240.015
organonitrogen compound biosynthetic processGO:1901566470.015
axon developmentGO:00615641660.015
regulation of dna recombinationGO:000001820.015
b cell mediated immunityGO:001972430.015
positive regulation of blood circulationGO:190352420.015
energy reserve metabolic processGO:000611220.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
brain developmentGO:00074202930.015
monocarboxylic acid catabolic processGO:007232930.015
negative regulation of intracellular transportGO:003238730.014
positive regulation of cell adhesionGO:004578510.014
histone deacetylationGO:001657520.014
peptidyl serine modificationGO:001820920.014
sensory perception of chemical stimulusGO:000760630.014
transcription from rna polymerase ii promoterGO:0006366800.014
cell morphogenesis involved in differentiationGO:00009041950.014
positive regulation of biosynthetic processGO:0009891680.014
regulation of synapse assemblyGO:005196330.014
membrane invaginationGO:001032410.014
reactive oxygen species biosynthetic processGO:190340910.014
ribonucleoside monophosphate catabolic processGO:000915840.014
positive regulation of stress activated mapk cascadeGO:003287430.014
protein localization to plasma membraneGO:007265910.014
synaptic growth at neuromuscular junctionGO:005112420.014
negative regulation of epithelial cell proliferationGO:005068010.014
cell matrix adhesionGO:000716040.014
adherens junction organizationGO:003433240.014
protein stabilizationGO:005082120.014
regulation of nucleoside metabolic processGO:000911820.014
oxoacid metabolic processGO:0043436310.014
determination of left right symmetryGO:00073681790.014
single organism biosynthetic processGO:0044711710.014
regulation of rna biosynthetic processGO:20011412130.014
organelle organizationGO:00069962270.014
cellular response to molecule of bacterial originGO:007121930.014
protein homooligomerizationGO:005126030.014
positive regulation of chromatin modificationGO:190331010.014
regulation of reproductive processGO:200024140.014
regulation of protein catabolic processGO:004217610.014
protein metabolic processGO:00195381830.014
gastrulationGO:00073692080.013
regulation of inflammatory responseGO:005072720.013
tube closureGO:006060610.013
embryonic organ developmentGO:00485683810.013
g1 s transition of mitotic cell cycleGO:000008210.013
phosphate containing compound metabolic processGO:00067961080.013
digestive tract morphogenesisGO:00485462310.013
regulation of cell shapeGO:000836010.013
regulation of response to nutrient levelsGO:003210710.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
phagocytosis engulfmentGO:000691110.013
generation of neuronsGO:00486993850.013
internal protein amino acid acetylationGO:000647520.013
positive regulation of cellular biosynthetic processGO:0031328680.013
positive regulation of cellular metabolic processGO:0031325940.013
positive regulation of leukocyte mediated immunityGO:000270510.013
cellular response to biotic stimulusGO:007121630.013
positive regulation of epithelial cell proliferationGO:005067910.013
tissue regenerationGO:0042246740.013
positive regulation of cell divisionGO:005178120.013
release of sequestered calcium ion into cytosolGO:005120930.013
immune system processGO:00023762410.013
regulation of sequestering of calcium ionGO:005128240.013
positive regulation of chromosome organizationGO:200125210.013
transportGO:00068102200.013
sleepGO:003043110.013
organophosphate biosynthetic processGO:0090407230.013
interspecies interaction between organismsGO:004441940.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
negative regulation of mapk cascadeGO:004340940.013
wnt signaling pathwayGO:0016055800.013
regulation of developmental processGO:00507932470.013
neuron projection developmentGO:00311751800.013
protein complex disassemblyGO:004324110.013
regulation of response to extracellular stimulusGO:003210410.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
taxisGO:00423301090.012
regulation of transcription dna templatedGO:00063552130.012
gtp metabolic processGO:004603940.012
urogenital system developmentGO:0001655970.012
negative regulation of synapse assemblyGO:005196420.012
spermatid developmentGO:000728620.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
meiotic cell cycle processGO:190304630.012
intracellular signal transductionGO:0035556850.012
positive regulation of epithelial cell migrationGO:001063420.012
macromolecular complex disassemblyGO:003298410.012
positive regulation of nucleoside metabolic processGO:004597910.012
negative regulation of signalingGO:0023057960.012
nitric oxide metabolic processGO:004620920.012
guanosine containing compound catabolic processGO:190106920.012
response to unfolded proteinGO:000698620.012
specification of symmetryGO:00097992040.012
somatic cell dna recombinationGO:001644410.012
neuron projection morphogenesisGO:00488121610.012
protein polymerizationGO:005125840.012
renal system developmentGO:0072001940.012
zymogen activationGO:003163830.012
regulation of synapse organizationGO:005080730.012
determination of heart left right asymmetryGO:00613711170.012
protein dephosphorylationGO:000647030.012
astrocyte differentiationGO:004870810.012
regulation of histone deacetylationGO:003106320.012
membrane lipid biosynthetic processGO:004646720.012
purine ribonucleoside biosynthetic processGO:004612920.011
post embryonic organ developmentGO:004856940.011
system processGO:00030081850.011
protein heterooligomerizationGO:005129110.011
cytosolic calcium ion transportGO:006040130.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
negative regulation of ras protein signal transductionGO:004658010.011
cell migrationGO:00164772370.011
microtubule organizing center organizationGO:003102310.011
rna localizationGO:000640340.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
synaptic target recognitionGO:000803910.011
response to monosaccharideGO:003428430.011
multi organism cellular processGO:004476420.011
ear developmentGO:00435831270.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
negative regulation of defense responseGO:003134820.011
glucose homeostasisGO:004259310.011
regulation of wound healingGO:006104120.011
stem cell differentiationGO:00488631170.011
regulation of purine nucleotide catabolic processGO:003312120.011
carbohydrate homeostasisGO:003350010.011
positive regulation of nucleotide catabolic processGO:003081310.011
regenerationGO:0031099910.011
positive regulation of jnk cascadeGO:004633030.011
hemopoiesisGO:00300971830.011
nephron tubule morphogenesisGO:007207810.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
response to other organismGO:0051707970.011
cytokinesisGO:000091030.011
regulation of establishment of protein localization to plasma membraneGO:009000310.011
skeletal system developmentGO:00015011810.011
regulation of carbohydrate biosynthetic processGO:004325510.011
signal transduction in absence of ligandGO:003803410.011
positive regulation of map kinase activityGO:004340630.011
regulation of cell developmentGO:00602841000.011
neuron developmentGO:00486662620.011
actin filament polymerizationGO:003004120.011
olfactory bulb developmentGO:002177240.011
catechol containing compound metabolic processGO:000971220.011
lipid catabolic processGO:001604240.011
single organism transportGO:00447652060.011
regulation of growth rateGO:004000910.010
regulation of response to biotic stimulusGO:000283120.010
erk1 and erk2 cascadeGO:007037140.010
macromolecule deacylationGO:009873230.010
myeloid cell differentiationGO:0030099860.010
negative regulation of response to stimulusGO:00485851040.010
exocytosisGO:000688710.010
neuromuscular synaptic transmissionGO:000727420.010
positive regulation of muscle cell differentiationGO:005114910.010
somatic muscle developmentGO:000752540.010
positive regulation of gene expressionGO:0010628710.010
inner ear developmentGO:00488391260.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
single organism localizationGO:19025782250.010
immunoglobulin productionGO:000237710.010
phasic smooth muscle contractionGO:001482110.010
response to uvGO:000941130.010
negative regulation of cell communicationGO:0010648960.010
purine containing compound biosynthetic processGO:0072522200.010
cellular amide metabolic processGO:004360340.010
regulation of systemic arterial blood pressureGO:000307310.010
positive regulation of camp metabolic processGO:003081620.010
regulation of glial cell differentiationGO:004568540.010
purine ribonucleoside monophosphate catabolic processGO:000916940.010
muscle structure developmentGO:00610611960.010
atp catabolic processGO:000620040.010
regulation of cell matrix adhesionGO:000195210.010

hpse2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
bone diseaseDOID:008000100.022
connective tissue diseaseDOID:6500.022
musculoskeletal system diseaseDOID:1700.022
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.017
disease of metabolismDOID:001466700.015
nervous system diseaseDOID:86300.011
cardiovascular system diseaseDOID:128700.011
eye diseaseDOID:561400.010
sensory system diseaseDOID:005015500.010
retinal diseaseDOID:567900.010
eye and adnexa diseaseDOID:149200.010