Danio rerio

43 known processes

notch2

notch homolog 2

(Aliases: sb:cb884,notch6)

notch2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.988
Zebrafish Mouse Fly
digestive tract morphogenesisGO:00485462310.936
Zebrafish Fly
skeletal system developmentGO:00015011810.927
neuron differentiationGO:00301823530.923
Zebrafish Fly
cellular component morphogenesisGO:00329893360.917
Zebrafish Fly
response to external stimulusGO:00096052640.908
Mouse Fly
heart developmentGO:00075073130.873
Human Mouse Fly
neuron projection developmentGO:00311751800.864
Zebrafish Fly
regulation of epithelial cell proliferationGO:005067830.864
eye developmentGO:00016542770.861
Mouse Fly
sensory organ morphogenesisGO:00905962000.853
Mouse Fly
mesenchyme developmentGO:00604851270.851
negative regulation of cellular processGO:00485232830.850
Human Zebrafish Mouse Fly
gastrulationGO:00073692080.844
Zebrafish
positive regulation of biological processGO:00485182530.830
Human Zebrafish Mouse Fly
embryonic organ morphogenesisGO:00485622740.811
Mouse
cellular macromolecule metabolic processGO:00442603910.810
Mouse Fly
blood vessel morphogenesisGO:00485142160.807
Zebrafish Mouse
brain developmentGO:00074202930.792
Zebrafish
axon guidanceGO:0007411860.779
Fly
negative regulation of gastrulationGO:2000542110.774
regulation of stem cell differentiationGO:200073640.754
Fly
cell projection organizationGO:00300302840.742
Zebrafish Fly
regulation of rna metabolic processGO:00512522240.735
Mouse Fly
cellular component movementGO:00069283350.730
Fly
heart morphogenesisGO:00030071560.725
Human Mouse
tube morphogenesisGO:00352393490.721
Zebrafish Mouse Fly
mesoderm developmentGO:0007498880.720
Zebrafish Fly
regulation of response to stimulusGO:00485832690.718
Human Mouse Fly
nucleobase containing compound biosynthetic processGO:00346542050.708
Mouse Fly
neuron projection guidanceGO:0097485860.701
Fly
morphogenesis of an epitheliumGO:00020093330.696
Mouse Fly
central nervous system developmentGO:00074173870.685
Zebrafish
chordate embryonic developmentGO:00430092710.642
Zebrafish Mouse
axon developmentGO:00615641660.642
Zebrafish Fly
negative regulation of embryonic developmentGO:0045992110.632
regulation of embryonic developmentGO:0045995470.623
Zebrafish
somitogenesisGO:0001756870.621
Zebrafish
notochord developmentGO:0030903540.614
organic cyclic compound biosynthetic processGO:19013622230.610
Mouse Fly
kidney developmentGO:0001822920.595
Zebrafish Mouse
head developmentGO:00603223030.594
camera type eye morphogenesisGO:00485931080.589
Mouse
regulation of primary metabolic processGO:00800903110.577
Mouse Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.574
Zebrafish Fly
neuron projection morphogenesisGO:00488121610.567
Zebrafish Fly
signal transductionGO:00071654550.565
Human Zebrafish Mouse Fly
retina development in camera type eyeGO:00600411460.561
cell projection morphogenesisGO:00488582440.560
Zebrafish Fly
response to inorganic substanceGO:0010035380.559
blood vessel developmentGO:00015682460.556
Zebrafish Mouse
cell morphogenesis involved in differentiationGO:00009041950.544
Zebrafish Fly
positive regulation of cellular metabolic processGO:0031325940.541
Fly
positive regulation of cellular processGO:00485222010.538
Human Zebrafish Mouse Fly
cell fate commitment involved in formation of primary germ layerGO:0060795260.538
Zebrafish
regulation of developmental processGO:00507932470.530
Zebrafish Mouse Fly
formation of primary germ layerGO:0001704620.524
Zebrafish
pancreas developmentGO:0031016840.520
Zebrafish
developmental growth involved in morphogenesisGO:0060560860.519
connective tissue developmentGO:0061448990.513
epithelial cell differentiationGO:00308551160.513
Mouse Fly
cell fate commitmentGO:0045165990.508
Zebrafish Rat Worm Fly
taxisGO:00423301090.501
Fly
segmentationGO:0035282970.497
Zebrafish Fly
negative regulation of cell fate specificationGO:0009996110.495
positive regulation of stem cell proliferationGO:200064810.491
single organism metabolic processGO:00447102170.490
regulation of endodermal cell differentiationGO:1903224150.488
Zebrafish
hepaticobiliary system developmentGO:0061008980.483
regulation of multicellular organismal developmentGO:20000262230.457
Zebrafish Mouse Fly
cell morphogenesisGO:00009022890.455
Zebrafish Fly
gland developmentGO:00487321430.455
regulation of macromolecule metabolic processGO:00602553170.441
Mouse Fly
nucleic acid templated transcriptionGO:00976591810.432
Mouse Fly
organic cyclic compound metabolic processGO:19013603010.426
Mouse Fly
cell proliferationGO:0008283800.423
Human Zebrafish Mouse Worm Fly
cell surface receptor signaling pathwayGO:00071663250.416
Zebrafish Mouse Fly
lateral inhibitionGO:004633110.413
Fly
regulation of cell developmentGO:00602841000.412
Zebrafish Fly
sensory organ developmentGO:00074233930.409
Mouse Fly
establishment of localizationGO:00512342440.405
Zebrafish Mouse Worm
forebrain generation of neuronsGO:0021872140.402
chondrocyte developmentGO:000206340.400
embryonic camera type eye developmentGO:0031076290.400
regulation of cellular metabolic processGO:00313233200.388
Mouse Fly
epidermal cell differentiationGO:0009913360.387
angiogenesisGO:00015251580.386
Mouse
cartilage developmentGO:0051216960.386
apoptotic processGO:00069151160.382
Mouse
heterocycle biosynthetic processGO:00181302150.377
Mouse Fly
somite developmentGO:0061053960.376
Zebrafish
embryonic skeletal system morphogenesisGO:0048704930.371
eye morphogenesisGO:00485921440.369
Mouse Fly
locomotionGO:00400113130.367
Worm Fly
ear developmentGO:00435831270.358
neuron developmentGO:00486662620.349
Zebrafish Fly
anterior posterior pattern specificationGO:00099521520.344
Zebrafish Fly
nitrogen compound metabolic processGO:00068073190.342
Mouse Fly
regulation of stem cell proliferationGO:007209120.336
embryonic heart tube developmentGO:00350501330.333
Mouse
cellular response to external stimulusGO:007149620.331
gene expressionGO:00104672520.329
Mouse Fly
ear morphogenesisGO:0042471640.327
positive regulation of jnk cascadeGO:004633030.321
positive regulation of signal transductionGO:0009967560.319
Human Mouse Fly
cellular aromatic compound metabolic processGO:00067252950.306
Mouse Fly
regulation of nitrogen compound metabolic processGO:00511712510.305
Mouse Fly
endocrine system developmentGO:0035270650.305
urogenital system developmentGO:0001655970.303
Zebrafish Mouse Fly
biosynthetic processGO:00090582940.301
Mouse Fly
rna biosynthetic processGO:00327741810.298
Mouse Fly
stem cell proliferationGO:007208940.297
extrinsic apoptotic signaling pathwayGO:009719130.290
positive regulation of nitrogen compound metabolic processGO:0051173690.289
Fly
morphogenesis of an epithelial sheetGO:0002011490.288
Mouse
inner ear developmentGO:00488391260.287
negative regulation of cell communicationGO:0010648960.284
regulation of cellular component organizationGO:0051128860.284
Zebrafish Worm Fly
cell projection assemblyGO:0030031640.282
Fly
inner ear receptor cell differentiationGO:0060113290.280
nucleocytoplasmic transportGO:000691340.277
positive regulation of transcription dna templatedGO:0045893570.276
Fly
skeletal system morphogenesisGO:00487051020.274
cell cell signaling involved in cell fate commitmentGO:0045168120.273
Worm Fly
deathGO:00162651210.269
Mouse
establishment of protein localization to organelleGO:007259440.268
developmental growthGO:00485891660.264
localization of cellGO:00516742440.263
Fly
chemotaxisGO:00069351040.263
Fly
retinal ganglion cell axon guidanceGO:0031290350.261
negative regulation of cell fate commitmentGO:0010454130.261
forebrain neuron differentiationGO:0021879140.258
sprouting angiogenesisGO:0002040530.254
cellular nitrogen compound metabolic processGO:00346412900.253
Mouse Fly
generation of neuronsGO:00486993850.246
Zebrafish Fly
regulation of chondrocyte differentiationGO:003233010.246
somatic stem cell maintenanceGO:003501910.244
Zebrafish
single organism transportGO:00447652060.243
Mouse
camera type eye developmentGO:00430102220.238
Mouse
muscle cell differentiationGO:00426921390.235
Fly
digestive system developmentGO:00551232890.234
Zebrafish Worm Fly
regulation of cellular biosynthetic processGO:00313262450.233
Mouse Fly
negative regulation of endodermal cell differentiationGO:190322580.232
cellular nitrogen compound biosynthetic processGO:00442712180.231
Mouse Fly
regulation of signalingGO:00230512350.229
Human Mouse Fly
photoreceptor cell differentiationGO:0046530550.225
Fly
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.225
vasculature developmentGO:00019442780.224
cilium assemblyGO:0042384580.222
regulation of nucleocytoplasmic transportGO:004682220.221
regulation of cell fate specificationGO:0042659200.219
Zebrafish Fly
hematopoietic or lymphoid organ developmentGO:00485341910.219
Mouse Fly
regulation of extrinsic apoptotic signaling pathwayGO:200123630.218
regulation of cell deathGO:00109411030.217
Mouse
negative regulation of response to stimulusGO:00485851040.215
heart joggingGO:0003146400.213
cell deathGO:00082191210.208
Mouse
cell part morphogenesisGO:00329902460.207
Zebrafish Fly
cellular protein metabolic processGO:00442671290.203
Fly
embryonic skeletal system developmentGO:0048706970.202
positive regulation of stress activated mapk cascadeGO:003287430.201
regulation of gene expressionGO:00104682650.201
Mouse Fly
response to chemicalGO:00422213200.201
Fly
regulation of biological qualityGO:00650082630.201
Zebrafish Fly
glial cell migrationGO:000834730.200
Fly
liver developmentGO:0001889960.198
regulation of cell substrate adhesionGO:001081010.197
cellular protein modification processGO:00064641000.193
Fly
bmp signaling pathwayGO:0030509520.193
Mouse
radial glial cell differentiationGO:006001920.192
Zebrafish
regulation of multicellular organismal processGO:00512392770.192
Zebrafish Mouse Fly
negative regulation of stem cell differentiationGO:200073720.192
regulation of cell communicationGO:00106462320.191
Human Mouse Fly
nucleobase containing compound metabolic processGO:00061392740.190
Mouse Fly
immune responseGO:0006955280.190
Mouse
positive regulation of cell proliferationGO:0008284150.189
Mouse Fly
central nervous system neuron differentiationGO:0021953740.188
Zebrafish
regulation of organ growthGO:004662030.187
cellular response to radiationGO:007147840.183
positive regulation of developmental processGO:0051094500.182
Zebrafish Mouse
agingGO:000756820.181
Worm Fly
regulation of macromolecule biosynthetic processGO:00105562250.179
Mouse Fly
regulation of cell differentiationGO:00455951420.179
Zebrafish Mouse Fly
transportGO:00068102200.178
Zebrafish Mouse Worm
positive regulation of cellular biosynthetic processGO:0031328680.177
Fly
heterocycle metabolic processGO:00464832900.175
Mouse Fly
regulation of rna biosynthetic processGO:20011412130.172
Mouse Fly
cellular response to organic substanceGO:00713101050.171
regulation of nucleic acid templated transcriptionGO:19035062130.170
Mouse Fly
organic substance biosynthetic processGO:19015762890.168
Mouse Fly
digestive tract developmentGO:00485652650.166
Zebrafish Worm Fly
mesenchymal cell proliferationGO:001046310.166
growthGO:00400071740.165
muscle fiber developmentGO:0048747520.165
negative regulation of signalingGO:0023057960.164
regulation of gastrulationGO:0010470240.164
Zebrafish
cellular component biogenesisGO:00440851780.163
Fly
nuclear transportGO:005116940.160
macromolecule biosynthetic processGO:00090592270.159
Mouse Fly
aromatic compound biosynthetic processGO:00194382170.157
Mouse Fly
positive regulation of response to stimulusGO:0048584800.157
Human Mouse Fly
cranial nerve developmentGO:0021545420.156
embryonic heart tube morphogenesisGO:00031431080.156
Mouse
appendage morphogenesisGO:0035107560.154
Mouse Fly
multicellular organism growthGO:003526440.153
regulation of nervous system developmentGO:0051960900.152
Zebrafish Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.151
Mouse Fly
single organism nuclear importGO:190259330.150
cell fate specificationGO:0001708680.150
Zebrafish Worm Fly
inner ear morphogenesisGO:0042472630.149
regulation of cell morphogenesis involved in differentiationGO:0010769380.149
phosphorus metabolic processGO:00067931090.149
Fly
immune system developmentGO:00025201910.148
Mouse Fly
diencephalon developmentGO:0021536580.148
Zebrafish
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.147
negative regulation of metabolic processGO:0009892860.146
Mouse Fly
mesenchymal cell differentiationGO:0048762870.145
embryo development ending in birth or egg hatchingGO:00097922710.145
Zebrafish Mouse Worm
embryonic eye morphogenesisGO:0048048300.144
endodermal cell fate specificationGO:0001714170.143
Zebrafish
regulation of multicellular organism growthGO:004001440.143
spinal cord radial glial cell differentiationGO:002153120.142
Zebrafish
bone developmentGO:0060348140.141
cell migrationGO:00164772370.140
Fly
response to molecule of bacterial originGO:0002237140.140
epithelial tube morphogenesisGO:00605621480.139
Mouse Fly
forebrain developmentGO:0030900960.137
Zebrafish
positive regulation of cell communicationGO:0010647560.136
Human Mouse Fly
positive regulation of biosynthetic processGO:0009891680.136
Fly
response to organic substanceGO:00100331530.134
regulation of canonical wnt signaling pathwayGO:0060828340.134
positive regulation of epithelial cell proliferationGO:005067910.133
regulation of developmental growthGO:0048638380.131
renal system developmentGO:0072001940.131
Zebrafish Mouse Fly
regulation of signal transductionGO:00099662250.128
Human Mouse Fly
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.126
Fly
axonogenesisGO:00074091520.126
Zebrafish Fly
mesenchymal cell developmentGO:0014031780.124
positive regulation of metabolic processGO:00098931080.124
Fly
negative regulation of multicellular organismal processGO:0051241690.119
Zebrafish Fly
regulation of notch signaling pathwayGO:0008593160.119
Fly
muscle organ developmentGO:00075171010.119
Worm Fly
extracellular structure organizationGO:0043062270.119
positive regulation of macromolecule metabolic processGO:0010604930.118
Fly
tissue remodelingGO:004877140.118
Human
cell motilityGO:00488702440.117
Fly
neural crest cell developmentGO:0014032620.117
regulation of programmed cell deathGO:00430671010.117
Mouse
regulation of cytoplasmic transportGO:190364940.116
tissue homeostasisGO:0001894250.114
single organism localizationGO:19025782250.113
Mouse
regulation of neuron differentiationGO:0045664560.113
Fly
regulation of metabolic processGO:00192223590.113
Mouse Fly
positive regulation of mesenchymal cell proliferationGO:000205310.113
macromolecule modificationGO:00434121110.112
Fly
embryonic cranial skeleton morphogenesisGO:0048701900.111
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.109
response to woundingGO:00096111160.109
protein targeting to nucleusGO:004474430.108
endocardial cushion formationGO:000327220.108
positive regulation of erk1 and erk2 cascadeGO:007037420.107
specification of organ identityGO:001009220.105
positive regulation of rna biosynthetic processGO:1902680570.104
Fly
outflow tract morphogenesisGO:000315110.104
regulation of biosynthetic processGO:00098892500.104
Mouse Fly
protein import into nucleusGO:000660630.104
small molecule metabolic processGO:0044281770.104
endodermal cell fate commitmentGO:0001711180.103
Zebrafish
cell growthGO:0016049570.101
Human
cellular response to extracellular stimulusGO:003166820.101
erk1 and erk2 cascadeGO:007037140.101
nephron developmentGO:0072006310.099
Mouse
heart loopingGO:0001947940.098
Mouse
regulation of mesenchymal cell proliferationGO:001046410.098
embryonic limb morphogenesisGO:003032620.098
Mouse
response to nutrientGO:000758430.098
mesodermal cell fate specificationGO:0007501120.098
Zebrafish
regionalizationGO:00030022740.098
Zebrafish Mouse Fly
regulation of erk1 and erk2 cascadeGO:007037240.098
cell substrate adhesionGO:003158940.096
transcription from rna polymerase ii promoterGO:0006366800.096
Mouse Fly
regulation of endothelial cell proliferationGO:000193610.096
stem cell maintenanceGO:001982740.096
Zebrafish Fly
negative regulation of blood vessel endothelial cell migrationGO:004353710.095
cellular response to chemical stimulusGO:00708871570.094
blood circulationGO:0008015870.094
Zebrafish
regulation of cell fate commitmentGO:0010453220.094
Zebrafish Fly
embryonic viscerocranium morphogenesisGO:0048703520.093
positive regulation of nucleic acid templated transcriptionGO:1903508570.092
Fly
negative regulation of epithelial cell proliferationGO:005068010.092
negative regulation of endodermal cell fate specificationGO:004266480.092
regulation of transcription dna templatedGO:00063552130.091
Mouse Fly
protein modification processGO:00362111000.091
Fly
organelle organizationGO:00069962270.091
Worm Fly
regulation of reproductive processGO:200024140.090
phosphate containing compound metabolic processGO:00067961080.089
Fly
neural crest cell migrationGO:0001755420.088
glial cell proliferationGO:001400940.088
regulation of cell morphogenesisGO:0022604420.088
osteoblast differentiationGO:000164950.087
negative regulation of macromolecule metabolic processGO:0010605760.087
Mouse Fly
regulation of protein transportGO:005122330.086
cellular ketone metabolic processGO:0042180110.086
regulation of anatomical structure morphogenesisGO:00226031300.085
Zebrafish Fly
cell adhesionGO:0007155400.085
Fly
negative regulation of signal transductionGO:0009968940.084
endodermal cell differentiationGO:0035987190.082
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:0045935690.081
Fly
endocardial cushion developmentGO:000319760.081
glucose homeostasisGO:004259310.081
stem cell developmentGO:0048864820.081
Zebrafish Fly
endodermal cell fate determinationGO:000749320.081
eye field cell fate commitment involved in camera type eye formationGO:006089830.081
olfactory placode developmentGO:0071698120.079
oocyte maturationGO:000155640.078
epidermis developmentGO:0008544480.077
endoderm developmentGO:0007492490.077
Zebrafish
response to stressGO:00069502630.076
macromolecule localizationGO:0033036540.076
Mouse
protein importGO:001703830.076
endothelial cell proliferationGO:0001935110.075
negative regulation of developmental growthGO:004864090.075
negative regulation of sequestering of calcium ionGO:005128340.074
transcription dna templatedGO:00063511810.074
Mouse Fly
embryonic camera type eye morphogenesisGO:0048596190.073
cilium morphogenesisGO:0060271850.072
regulation of protein targetingGO:190353320.072
protein phosphorylationGO:0006468470.072
Fly
mesodermal cell differentiationGO:0048333210.072
Zebrafish
specification of symmetryGO:00097992040.071
Zebrafish Mouse
regulation of cellular component movementGO:0051270550.071
positive regulation of canonical wnt signaling pathwayGO:009026340.071
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.070
cellular response to molecule of bacterial originGO:007121930.070
regulation of cell proliferationGO:0042127370.069
Human Mouse Worm Fly
homeostatic processGO:00425921420.069
Fly
vesicle mediated transportGO:0016192220.069
Zebrafish Worm
regulation of protein import into nucleusGO:004230620.069
response to lipidGO:0033993600.069
protein localization to nucleusGO:003450430.068
retina morphogenesis in camera type eyeGO:0060042790.068
epithelial cell proliferationGO:0050673170.067
Fly
growth plate cartilage developmentGO:000341720.067
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.066
morphogenesis of embryonic epitheliumGO:0016331300.066
compound eye developmentGO:004874920.066
Fly
single organism organelle organizationGO:19025891990.065
Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.065
Mouse Fly
system processGO:00030081850.065
Zebrafish Fly
negative regulation of axon extensionGO:003051770.065
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.065
Mouse
regulation of localizationGO:00328791040.064
Zebrafish
endocytosisGO:0006897160.064
Zebrafish Worm
positive regulation of cell deathGO:0010942290.064
Mouse
regulation of endodermal cell fate specificationGO:0042663150.063
Zebrafish
endocrine pancreas developmentGO:0031018270.063
response to metal ionGO:0010038340.063
positive regulation of transportGO:005105020.063
developmental cell growthGO:0048588520.063
neuron projection regenerationGO:0031102160.063
regenerationGO:0031099910.063
anatomical structure homeostasisGO:0060249360.062
regulation of intracellular protein transportGO:003315730.061
positive regulation of neuron apoptotic processGO:004352510.060
positive regulation of rna metabolic processGO:0051254590.060
Fly
regulation of establishment of protein localizationGO:007020140.060
phosphorylationGO:0016310690.059
Fly
septum transversum developmentGO:000334340.059
eye photoreceptor cell differentiationGO:0001754450.059
Fly
positive regulation of response to external stimulusGO:003210390.059
positive regulation of gene expressionGO:0010628710.059
Fly
determination of left right symmetryGO:00073681790.057
Zebrafish Mouse
nerve developmentGO:0021675450.057
positive regulation of wound healingGO:009030310.057
atrioventricular valve formationGO:000319030.056
embryonic camera type eye formationGO:0060900100.056
notch signaling pathwayGO:0007219350.056
Zebrafish Fly
regulation of wnt signaling pathwayGO:0030111530.056
negative regulation of biological processGO:00485193040.056
Human Zebrafish Mouse Fly
programmed cell deathGO:00125011190.056
Mouse
ossificationGO:0001503230.055
regulation of synapse assemblyGO:005196330.055
olfactory lobe developmentGO:002198840.054
regulation of response to stressGO:0080134360.054
neural retina developmentGO:0003407490.053
determination of heart left right asymmetryGO:00613711170.053
Mouse
behaviorGO:0007610740.053
Worm Fly
cellular response to nutrient levelsGO:003166920.053
positive regulation of cellular amino acid metabolic processGO:004576400.052
cell differentiation in spinal cordGO:0021515400.052
Zebrafish
regulation of dna replicationGO:000627530.052
neural crest cell differentiationGO:0014033720.052
positive regulation of protein kinase b signalingGO:005189710.052
response to external biotic stimulusGO:0043207970.051
Mouse Fly
mechanoreceptor differentiationGO:0042490370.050
regulation of cellular ketone metabolic processGO:001056570.050
phagocytosisGO:000690930.050
branching morphogenesis of a nerveGO:004875540.050
motor neuron axon guidanceGO:0008045230.049
Fly
cellular amino acid metabolic processGO:000652070.049
regulation of neurogenesisGO:0050767870.049
Zebrafish Fly
cellular macromolecule biosynthetic processGO:00346452240.049
Mouse Fly
pronephros developmentGO:0048793690.049
Zebrafish
establishment of localization in cellGO:0051649770.048
Mouse
cellular component assemblyGO:00226071700.048
Fly
muscle structure developmentGO:00610611960.048
Worm Fly
immune system processGO:00023762410.048
Mouse Fly
inner ear receptor cell developmentGO:0060119200.048
positive regulation of macromolecule biosynthetic processGO:0010557590.048
Fly
negative regulation of reproductive processGO:200024230.047
multicellular organismal metabolic processGO:004423620.047
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.046
nucleic acid metabolic processGO:00903042440.045
Mouse Fly
skin morphogenesisGO:004358970.045
response to vitaminGO:003327330.045
optic placode formation involved in camera type eye formationGO:004661930.045
skeletal muscle organ developmentGO:0060538780.045
Fly
hindbrain developmentGO:0030902910.044
Zebrafish
protein metabolic processGO:00195381830.044
Fly
regulation of intracellular signal transductionGO:1902531570.044
Human
wnt signaling pathwayGO:0016055800.044
olfactory bulb developmentGO:002177240.044
regulation of cellular protein metabolic processGO:0032268520.044
negative regulation of protein phosphorylationGO:000193340.044
regulation of synapse organizationGO:005080730.044
regulation of transcription from rna polymerase ii promoterGO:00063571140.043
Mouse Fly
alcohol biosynthetic processGO:004616520.043
cartilage condensationGO:000150230.043
negative regulation of cell developmentGO:0010721260.043
Zebrafish Fly
regulation of protein modification by small protein conjugation or removalGO:190332030.043
neural tube developmentGO:0021915620.043
collagen metabolic processGO:003296320.042
paraxial mesoderm developmentGO:004833980.042
multicellular organismal macromolecule metabolic processGO:004425920.042
activation of mapk activityGO:000018730.042
regulation of organ morphogenesisGO:2000027350.042
Zebrafish Fly
cellular response to stressGO:0033554620.042
positive regulation of epithelial cell differentiationGO:003085820.042
epithelial to mesenchymal transitionGO:0001837210.041
wound healingGO:0042060900.041
negative regulation of wnt signaling pathwayGO:0030178300.041
regulation of response to external stimulusGO:0032101310.040
cytosolic calcium ion transportGO:006040130.040
positive regulation of endothelial cell proliferationGO:000193810.040
muscle cell developmentGO:00550011150.040
canonical wnt signaling pathwayGO:0060070480.040
endoderm formationGO:0001706290.039
Zebrafish
developmental maturationGO:0021700340.039
cellular biosynthetic processGO:00442492860.039
Mouse Fly
extracellular matrix organizationGO:0030198270.039
epithelial cell morphogenesisGO:000338220.039
regulation of catenin import into nucleusGO:003541220.039
regulation of apoptotic processGO:0042981980.039
Mouse
release of sequestered calcium ion into cytosolGO:005120930.039
cilium organizationGO:0044782710.038
optic nerve morphogenesisGO:002163160.037
regulation of chemotaxisGO:0050920180.037
regulation of protein metabolic processGO:0051246560.037
positive regulation of cell differentiationGO:0045597300.037
Zebrafish Mouse
nuclear importGO:005117030.037
negative regulation of cell cycleGO:0045786140.037
Human
response to acid chemicalGO:0001101170.036
axon regenerationGO:0031103140.036
negative regulation of protein kinase activityGO:000646940.036
regulation of axonogenesisGO:0050770320.036
ameboidal type cell migrationGO:00016671430.036
Fly
proepicardium developmentGO:000334240.036
positive regulation of apoptotic signaling pathwayGO:200123510.036
rhombomere formationGO:0021594120.036
Zebrafish
regulation of cardiac muscle tissue developmentGO:005502410.036
negative regulation of cell differentiationGO:0045596460.036
Zebrafish Fly
regulation of protein localization to nucleusGO:190018020.035
negative regulation of axonogenesisGO:005077170.035
response to abiotic stimulusGO:00096281220.035
negative regulation of neurogenesisGO:0050768200.035
Zebrafish Fly
regulation of protein ubiquitinationGO:003139630.035
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.035
regulation of cell matrix adhesionGO:000195210.035
regulation of protein kinase b signalingGO:005189680.035
vasculogenesisGO:0001570410.034
negative regulation of gene expressionGO:0010629650.034
Mouse Fly
determination of bilateral symmetryGO:00098552040.034
Zebrafish Mouse
mesoderm formationGO:0001707430.034
Zebrafish
cellular response to lipidGO:0071396390.034
negative regulation of developmental processGO:0051093650.034
Zebrafish Fly
response to mechanical stimulusGO:0009612240.034
regulation of phosphorus metabolic processGO:0051174430.034
odontogenesis of dentin containing toothGO:004247510.034

notch2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.405
Human
musculoskeletal system diseaseDOID:1700.131
connective tissue diseaseDOID:6500.131
bone diseaseDOID:008000100.079
bone development diseaseDOID:008000600.079
nervous system diseaseDOID:86300.037
dysostosisDOID:193400.034