Danio rerio

33 known processes

metap2

methionyl aminopeptidase 2

(Aliases: wu:fb98h06,zgc:66250)

metap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myeloid cell differentiationGO:0030099860.441
convergent extension involved in gastrulationGO:0060027710.231
gene expressionGO:00104672520.225
immune system processGO:00023762410.183
hematopoietic stem cell differentiationGO:0060218200.182
i kappab kinase nf kappab signalingGO:000724940.158
muscle organ developmentGO:00075171010.158
heterocycle biosynthetic processGO:00181302150.156
response to external stimulusGO:00096052640.155
skeletal muscle organ developmentGO:0060538780.145
cellular macromolecule biosynthetic processGO:00346452240.141
cell cycleGO:0007049930.135
regulation of macromolecule metabolic processGO:00602553170.129
cellular response to external stimulusGO:007149620.129
morphogenesis of an epitheliumGO:00020093330.125
regulation of protein complex assemblyGO:004325430.123
larval developmentGO:000216420.118
striated muscle cell differentiationGO:00511461290.118
regulation of gene expressionGO:00104682650.116
response to other organismGO:0051707970.110
microtubule based processGO:0007017600.108
muscle structure developmentGO:00610611960.106
organelle organizationGO:00069962270.101
digestive tract developmentGO:00485652650.101
cellular macromolecule metabolic processGO:00442603910.100
definitive hemopoiesisGO:0060216180.093
hematopoietic or lymphoid organ developmentGO:00485341910.084
actin filament polymerizationGO:003004120.083
protein polymerizationGO:005125840.082
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.080
neutrophil migrationGO:1990266100.079
convergent extensionGO:00600261180.079
immune system developmentGO:00025201910.078
digestive system developmentGO:00551232890.075
regionalizationGO:00030022740.075
regulation of rna metabolic processGO:00512522240.072
homeostasis of number of cellsGO:0048872620.070
organic substance biosynthetic processGO:19015762890.070
positive regulation of protein complex assemblyGO:003133420.069
striated muscle tissue developmentGO:00147061100.069
neuron differentiationGO:00301823530.069
negative regulation of cellular processGO:00485232830.068
nucleic acid metabolic processGO:00903042440.067
muscle cell differentiationGO:00426921390.066
erythrocyte differentiationGO:0030218540.066
hematopoietic progenitor cell differentiationGO:0002244230.066
hemopoiesisGO:00300971830.065
cellular biosynthetic processGO:00442492860.065
regulation of response to stimulusGO:00485832690.064
macrophage differentiationGO:003022570.064
regulation of primary metabolic processGO:00800903110.063
single organism organelle organizationGO:19025891990.062
heterocycle metabolic processGO:00464832900.061
organic cyclic compound metabolic processGO:19013603010.061
deathGO:00162651210.060
homeostatic processGO:00425921420.060
positive regulation of cellular component biogenesisGO:004408930.060
erythrocyte homeostasisGO:0034101550.059
regulation of synaptic growth at neuromuscular junctionGO:000858210.059
organic cyclic compound biosynthetic processGO:19013622230.058
cellular response to chemical stimulusGO:00708871570.058
embryonic organ developmentGO:00485683810.057
biosynthetic processGO:00090582940.056
regulation of biological qualityGO:00650082630.055
embryo development ending in birth or egg hatchingGO:00097922710.055
Worm
regulation of signal transductionGO:00099662250.054
negative regulation of biological processGO:00485193040.054
regulation of multicellular organismal processGO:00512392770.054
regulation of cellular metabolic processGO:00313233200.054
regulation of protein polymerizationGO:003227120.053
leukocyte migrationGO:0050900150.052
cellular nitrogen compound metabolic processGO:00346412900.051
digestive tract morphogenesisGO:00485462310.051
cell surface receptor signaling pathwayGO:00071663250.049
aromatic compound biosynthetic processGO:00194382170.049
spermatid differentiationGO:004851520.049
mitotic cell cycleGO:0000278640.048
myeloid cell homeostasisGO:0002262560.048
cellular response to molecule of bacterial originGO:007121930.048
localization of cellGO:00516742440.047
response to biotic stimulusGO:0009607970.047
response to stressGO:00069502630.047
macromolecule biosynthetic processGO:00090592270.046
somite developmentGO:0061053960.046
vasculature developmentGO:00019442780.046
signal transductionGO:00071654550.045
epithelial cell morphogenesisGO:000338220.045
regulation of metabolic processGO:00192223590.044
actin polymerization or depolymerizationGO:000815420.043
spermatid developmentGO:000728620.043
negative regulation of multicellular organismal processGO:0051241690.042
angiogenesisGO:00015251580.042
nucleobase containing compound biosynthetic processGO:00346542050.042
cellular component movementGO:00069283350.041
regulation of nitrogen compound metabolic processGO:00511712510.041
positive regulation of cellular processGO:00485222010.041
gastrulationGO:00073692080.041
locomotionGO:00400113130.040
system processGO:00030081850.040
establishment of protein localization to organelleGO:007259440.039
cellular component biogenesisGO:00440851780.038
regulation of rna biosynthetic processGO:20011412130.038
antimicrobial humoral responseGO:001973020.038
nucleic acid templated transcriptionGO:00976591810.038
regulation of nucleic acid templated transcriptionGO:19035062130.037
response to chemicalGO:00422213200.037
cellular response to lipopolysaccharideGO:007122230.037
cell cycle processGO:0022402530.036
myotube differentiationGO:0014902450.036
myeloid leukocyte migrationGO:0097529120.036
rna metabolic processGO:00160702190.036
cytoskeleton organizationGO:0007010960.036
anterior posterior pattern specificationGO:00099521520.035
meiotic nuclear divisionGO:000712640.035
specification of symmetryGO:00097992040.035
proteasomal protein catabolic processGO:001049820.034
regulation of synapse assemblyGO:005196330.034
protein complex assemblyGO:0006461300.034
nitrogen compound metabolic processGO:00068073190.033
cell motilityGO:00488702440.033
actin filament based movementGO:003004810.033
agingGO:000756820.033
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.033
macrophage chemotaxisGO:004824630.032
mitochondrion organizationGO:000700540.032
regulation of transcription dna templatedGO:00063552130.031
wnt signaling pathwayGO:0016055800.031
positive regulation of biological processGO:00485182530.031
regulation of reproductive processGO:200024140.031
protein metabolic processGO:00195381830.030
Worm
cellular component assemblyGO:00226071700.030
cellular aromatic compound metabolic processGO:00067252950.030
cellular amide metabolic processGO:004360340.029
aorta developmentGO:003590440.029
pronephros morphogenesisGO:0072114140.029
establishment of localizationGO:00512342440.029
Worm
gland developmentGO:00487321430.029
muscle tissue developmentGO:00605371100.028
regulation of signalingGO:00230512350.028
positive regulation of protein polymerizationGO:003227320.027
neuron projection developmentGO:00311751800.027
protein complex biogenesisGO:0070271300.027
embryonic heart tube morphogenesisGO:00031431080.027
determination of heart left right asymmetryGO:00613711170.027
epithelial tube morphogenesisGO:00605621480.027
regulation of cellular biosynthetic processGO:00313262450.027
transcription dna templatedGO:00063511810.026
protein localization to nucleusGO:003450430.026
stem cell differentiationGO:00488631170.026
cellular component morphogenesisGO:00329893360.026
generation of neuronsGO:00486993850.026
response to lipidGO:0033993600.026
cellular response to nutrient levelsGO:003166920.026
peptide metabolic processGO:000651810.025
regulation of cell proliferationGO:0042127370.025
blood circulationGO:0008015870.025
leukocyte differentiationGO:0002521250.025
intracellular signal transductionGO:0035556850.025
regulation of response to biotic stimulusGO:000283120.025
amine metabolic processGO:000930820.025
organelle assemblyGO:00709251100.025
b cell differentiationGO:003018310.025
positive regulation of map kinase activityGO:004340630.024
blood vessel morphogenesisGO:00485142160.024
atrioventricular valve formationGO:000319030.024
somitogenesisGO:0001756870.024
rna biosynthetic processGO:00327741810.024
heart processGO:0003015710.024
response to abiotic stimulusGO:00096281220.024
protein importGO:001703830.024
regulation of molecular functionGO:0065009700.024
maintenance of locationGO:005123540.023
positive regulation of cytokine productionGO:000181920.023
cellular protein catabolic processGO:004425740.023
phosphorus metabolic processGO:00067931090.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
regulation of cell activationGO:005086510.023
single organism nuclear importGO:190259330.023
nuclear transportGO:005116940.023
regulation of organelle assemblyGO:190211540.023
regulation of biosynthetic processGO:00098892500.023
canonical wnt signaling pathwayGO:0060070480.023
nuclear importGO:005117030.022
regulation of macromolecule biosynthetic processGO:00105562250.022
regulation of neutrophil migrationGO:190262260.022
synaptic growth at neuromuscular junctionGO:005112420.022
nucleobase containing compound metabolic processGO:00061392740.022
regulation of multicellular organismal developmentGO:20000262230.022
single organism transportGO:00447652060.022
negative regulation of signal transductionGO:0009968940.022
regulation of developmental processGO:00507932470.022
phosphorylationGO:0016310690.022
cellular protein metabolic processGO:00442671290.021
regulation of cytokine productionGO:000181730.021
myeloid cell developmentGO:0061515320.021
granulocyte migrationGO:0097530110.021
programmed cell deathGO:00125011190.021
regulation of cell communicationGO:00106462320.021
granulocyte chemotaxisGO:0071621110.021
regulation of synapse organizationGO:005080730.020
cellular response to organic substanceGO:00713101050.020
positive regulation of multi organism processGO:004390230.020
regulation of cellular macromolecule biosynthetic processGO:20001122220.020
regulation of cellular component organizationGO:0051128860.020
regulation of canonical wnt signaling pathwayGO:0060828340.020
lipid homeostasisGO:005508830.020
protein targeting to nucleusGO:004474430.020
cellular response to extracellular stimulusGO:003166820.019
regulation of metal ion transportGO:001095940.019
actin mediated cell contractionGO:007025210.019
leukocyte proliferationGO:007066110.019
g1 s transition of mitotic cell cycleGO:000008210.019
negative regulation of nervous system developmentGO:0051961220.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
stem cell maintenanceGO:001982740.019
leukocyte chemotaxisGO:0030595120.019
cell projection organizationGO:00300302840.019
venous blood vessel developmentGO:006084190.019
macromolecular complex subunit organizationGO:0043933740.019
regulation of cell proliferation involved in heart morphogenesisGO:200013620.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
tube morphogenesisGO:00352393490.019
positive regulation of cell cycleGO:004578730.019
cellular amino acid metabolic processGO:000652070.019
regulation of cellular amino acid metabolic processGO:000652100.019
b cell activationGO:004211320.019
axon developmentGO:00615641660.019
regulation of protein metabolic processGO:0051246560.019
muscle cell developmentGO:00550011150.018
pericardium developmentGO:006003910.018
cell part morphogenesisGO:00329902460.018
regulation of inflammatory responseGO:005072720.018
circulatory system processGO:0003013870.018
endosomal transportGO:001619720.018
positive regulation of cytoskeleton organizationGO:005149530.018
negative regulation of synapse assemblyGO:005196420.018
muscle attachmentGO:001620390.018
multi organism processGO:00517041340.017
Worm
exocrine system developmentGO:0035272280.017
regulation of epithelial cell proliferationGO:005067830.017
protein acetylationGO:000647320.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
organic acid metabolic processGO:0006082310.017
regulation of cellular amine metabolic processGO:003323800.017
lymphocyte proliferationGO:004665110.017
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.017
growthGO:00400071740.017
heart loopingGO:0001947940.017
regulation of calcium ion transportGO:005192420.016
monocyte differentiationGO:003022420.016
response to external biotic stimulusGO:0043207970.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
protein modification processGO:00362111000.016
neutrophil chemotaxisGO:0030593100.016
phosphate containing compound metabolic processGO:00067961080.016
embryonic organ morphogenesisGO:00485622740.016
central nervous system developmentGO:00074173870.016
regulation of production of molecular mediator of immune responseGO:000270010.016
regulation of stem cell proliferationGO:007209120.016
lipid storageGO:001991510.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
negative regulation of developmental processGO:0051093650.016
cellular response to biotic stimulusGO:007121630.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
cellular chemical homeostasisGO:0055082170.015
production of molecular mediator of immune responseGO:000244020.015
epidermis developmentGO:0008544480.015
brain developmentGO:00074202930.015
tissue remodelingGO:004877140.015
female gonad developmentGO:000858540.015
sensory organ developmentGO:00074233930.015
neuroblast proliferationGO:000740520.015
actin cytoskeleton organizationGO:0030036630.015
positive regulation of molecular functionGO:0044093330.015
nucleocytoplasmic transportGO:000691340.015
meiotic chromosome segregationGO:004513230.015
interspecies interaction between organismsGO:004441940.015
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of cell shapeGO:000836010.014
carboxylic acid metabolic processGO:0019752220.014
erythrocyte maturationGO:004324980.014
protein import into nucleusGO:000660630.014
muscle fiber developmentGO:0048747520.014
connective tissue developmentGO:0061448990.014
regulation of phosphate metabolic processGO:0019220430.014
regulation of sequence specific dna binding transcription factor activityGO:005109090.014
eye photoreceptor cell developmentGO:0042462300.014
guanosine containing compound metabolic processGO:190106840.014
somatic stem cell maintenanceGO:003501910.014
determination of left right symmetryGO:00073681790.014
cellular ketone metabolic processGO:0042180110.014
embryonic heart tube developmentGO:00350501330.014
single organism metabolic processGO:00447102170.014
positive regulation of translationGO:004572710.014
small molecule metabolic processGO:0044281770.014
striated muscle cell developmentGO:00550021080.014
regulation of cellular ketone metabolic processGO:001056570.014
ubiquitin dependent protein catabolic processGO:000651130.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
segmentationGO:0035282970.014
heart morphogenesisGO:00030071560.014
protein acylationGO:004354330.014
sleepGO:003043110.014
cell migration involved in gastrulationGO:0042074790.014
cell proliferationGO:0008283800.013
protein complex subunit organizationGO:0071822460.013
regulation of circadian sleep wake cycleGO:004274910.013
development of primary female sexual characteristicsGO:004654540.013
establishment of endothelial barrierGO:006102830.013
head developmentGO:00603223030.013
regulation of growthGO:0040008420.013
cell deathGO:00082191210.013
positive regulation of cytokine biosynthetic processGO:004210810.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
mononuclear cell proliferationGO:003294310.013
negative regulation of wnt signaling pathwayGO:0030178300.013
regulation of response to external stimulusGO:0032101310.013
positive regulation of stress activated mapk cascadeGO:003287430.013
regulation of cell migrationGO:0030334400.013
circadian sleep wake cycle sleepGO:005080210.013
negative regulation of gene expressionGO:0010629650.013
epithelial cell developmentGO:0002064420.013
limb bud formationGO:006017420.013
skeletal muscle tissue developmentGO:0007519670.013
extrinsic apoptotic signaling pathwayGO:009719130.013
cell migrationGO:00164772370.013
negative regulation of cell communicationGO:0010648960.013
retinal rod cell developmentGO:004654840.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
cellular response to starvationGO:000926710.013
ribosomal small subunit biogenesisGO:004227420.012
regulation of organ growthGO:004662030.012
chemical homeostasisGO:0048878490.012
regulation of multicellular organism growthGO:004001440.012
meiotic cell cycle processGO:190304630.012
phagocytosisGO:000690930.012
neuron developmentGO:00486662620.012
small molecule catabolic processGO:004428230.012
ventricular cardiac muscle tissue developmentGO:000322930.012
positive regulation of metabolic processGO:00098931080.012
positive regulation of striated muscle cell differentiationGO:005115510.012
regulation of cell motilityGO:2000145460.012
cell cycle g1 s phase transitionGO:004484310.012
posttranscriptional regulation of gene expressionGO:0010608140.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
regulation of cytokine biosynthetic processGO:004203510.012
eye developmentGO:00016542770.012
negative regulation of protein localization to nucleusGO:190018120.012
regulation of neurological system processGO:003164420.012
gastrulation with mouth forming secondGO:0001702440.012
response to oxygen containing compoundGO:1901700550.012
embryonic hemopoiesisGO:0035162530.012
transportGO:00068102200.012
Worm
urogenital system developmentGO:0001655970.012
regulation of transmembrane transporter activityGO:002289820.012
circadian sleep wake cycleGO:004274520.012
regulation of cell matrix adhesionGO:000195210.012
entrainment of circadian clock by photoperiodGO:004315310.012
metal ion transportGO:0030001580.012
cell proliferation involved in heart morphogenesisGO:006132320.012
locomotor rhythmGO:004547530.012
erk1 and erk2 cascadeGO:007037140.012
regulation of protein transportGO:005122330.012
response to organic substanceGO:00100331530.011
negative regulation of cellular metabolic processGO:0031324770.011
nephron tubule morphogenesisGO:007207810.011
cell projection morphogenesisGO:00488582440.011
heart contractionGO:0060047710.011
chordate embryonic developmentGO:00430092710.011
cellular process involved in reproduction in multicellular organismGO:0022412280.011
autophagyGO:000691440.011
multicellular organism growthGO:003526440.011
positive regulation of chromosome organizationGO:200125210.011
regulation of carbohydrate metabolic processGO:000610940.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
germ cell developmentGO:0007281220.011
positive regulation of catabolic processGO:000989640.011
heart valve formationGO:000318840.011
positive regulation of cellular catabolic processGO:003133130.011
regulation of circadian sleep wake cycle sleepGO:004518710.011
microtubule cytoskeleton organizationGO:0000226330.011
cellular modified amino acid metabolic processGO:000657530.011
modification dependent macromolecule catabolic processGO:004363230.011
regulation of organelle organizationGO:0033043290.011
cellular protein modification processGO:00064641000.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
cellular amine metabolic processGO:004410620.011
tissue migrationGO:0090130370.011
somatic muscle developmentGO:000752540.011
negative regulation of response to stimulusGO:00485851040.011
negative regulation of multi organism processGO:004390130.011
lymphocyte activationGO:0046649100.011
cell chemotaxisGO:0060326170.011
macromolecule modificationGO:00434121110.011
actin filament based processGO:0030029640.011
negative regulation of protein transportGO:005122430.011
mesenchyme developmentGO:00604851270.011
regulation of cellular component movementGO:0051270550.011
fat soluble vitamin metabolic processGO:000677540.011
internal peptidyl lysine acetylationGO:001839320.011
cognitionGO:005089010.011
protein complex localizationGO:003150310.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
regulation of anatomical structure morphogenesisGO:00226031300.011
peptidyl amino acid modificationGO:0018193160.011
dorsal ventral pattern formationGO:00099531250.010
peptidyl threonine phosphorylationGO:001810710.010
spindle assembly involved in mitosisGO:009030710.010
ribonucleoside monophosphate catabolic processGO:000915840.010
organic acid catabolic processGO:001605430.010
myotube cell developmentGO:0014904350.010
regulation of programmed cell deathGO:00430671010.010
regulation of nervous system developmentGO:0051960900.010
cell morphogenesisGO:00009022890.010
regulation of blood vessel sizeGO:005088020.010
embryonic cranial skeleton morphogenesisGO:0048701900.010
negative regulation of dna metabolic processGO:005105340.010
divalent inorganic cation homeostasisGO:0072507220.010
regulation of bindingGO:005109830.010
cytokine metabolic processGO:004210710.010
female sex differentiationGO:004666040.010
regulation of meiotic cell cycleGO:005144510.010
modification dependent protein catabolic processGO:001994130.010
mitotic cell cycle processGO:1903047480.010
spliceosomal complex assemblyGO:000024510.010
regulation of skeletal muscle tissue developmentGO:004864140.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
stem cell proliferationGO:007208940.010
toll like receptor signaling pathwayGO:000222440.010
cytokinesisGO:000091030.010
negative regulation of chromosome organizationGO:200125110.010
cell matrix adhesionGO:000716040.010

metap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.028
disease of cellular proliferationDOID:1456600.028
disease of anatomical entityDOID:700.020
organ system cancerDOID:005068600.019
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.014
immune system diseaseDOID:291400.013
hematopoietic system diseaseDOID:7400.013