Danio rerio

34 known processes

lum

lumican

(Aliases: zgc:86661)

lum biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.430
immune system processGO:00023762410.194
rna biosynthetic processGO:00327741810.181
Mouse
regulation of macromolecule metabolic processGO:00602553170.175
Mouse
larval developmentGO:000216420.171
regulation of rna biosynthetic processGO:20011412130.170
Mouse
regulation of gene expressionGO:00104682650.164
Mouse
sensory organ developmentGO:00074233930.161
neuron differentiationGO:00301823530.156
gene expressionGO:00104672520.156
Mouse
cell substrate adhesionGO:003158940.153
regulation of establishment of protein localizationGO:007020140.145
nitrogen compound metabolic processGO:00068073190.137
Zebrafish Mouse
regulation of primary metabolic processGO:00800903110.135
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.133
Mouse
signal transductionGO:00071654550.131
response to drugGO:004249330.123
generation of neuronsGO:00486993850.120
morphogenesis of an epitheliumGO:00020093330.118
Zebrafish
rna metabolic processGO:00160702190.117
Mouse
agingGO:000756820.116
myotube differentiationGO:0014902450.115
nucleobase containing compound biosynthetic processGO:00346542050.114
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.112
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063571140.111
Mouse
positive regulation of programmed cell deathGO:0043068290.105
muscle cell differentiationGO:00426921390.105
regulation of biosynthetic processGO:00098892500.102
Mouse
regulation of meiotic cell cycleGO:005144510.100
nucleic acid metabolic processGO:00903042440.100
Mouse
neuron developmentGO:00486662620.095
regulation of signalingGO:00230512350.094
vasculature developmentGO:00019442780.091
specification of symmetryGO:00097992040.088
skeletal muscle organ developmentGO:0060538780.087
programmed cell deathGO:00125011190.087
digestive tract morphogenesisGO:00485462310.086
single organism metabolic processGO:00447102170.086
Zebrafish
cellular nitrogen compound metabolic processGO:00346412900.084
Mouse
multicellular organismal signalingGO:0035637220.082
aromatic compound biosynthetic processGO:00194382170.081
Mouse
cell matrix adhesionGO:000716040.081
regulation of developmental processGO:00507932470.080
regulation of cell substrate adhesionGO:001081010.079
regulation of stem cell proliferationGO:007209120.079
regulation of cellular biosynthetic processGO:00313262450.076
Mouse
positive regulation of biological processGO:00485182530.076
Mouse
transcription from rna polymerase ii promoterGO:0006366800.076
Mouse
regulation of protein transportGO:005122330.075
digestive tract developmentGO:00485652650.074
regulation of metabolic processGO:00192223590.072
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.070
Mouse
nucleobase containing compound metabolic processGO:00061392740.069
Mouse
blood vessel developmentGO:00015682460.067
regulation of signal transductionGO:00099662250.065
embryonic organ morphogenesisGO:00485622740.065
organic acid metabolic processGO:0006082310.065
Zebrafish
carboxylic acid metabolic processGO:0019752220.064
meiotic nuclear divisionGO:000712640.063
regulation of nucleobase containing compound metabolic processGO:00192192500.062
Mouse
regulation of response to stimulusGO:00485832690.062
regulation of apoptotic processGO:0042981980.061
heterocycle metabolic processGO:00464832900.061
Mouse
negative regulation of biological processGO:00485193040.060
response to external stimulusGO:00096052640.059
stem cell proliferationGO:007208940.059
regulation of multicellular organismal processGO:00512392770.059
cellular aromatic compound metabolic processGO:00067252950.059
Mouse
cellular component morphogenesisGO:00329893360.058
cellular response to extracellular stimulusGO:003166820.057
cellular biosynthetic processGO:00442492860.057
Mouse
cellular amine metabolic processGO:004410620.057
regulation of extrinsic apoptotic signaling pathwayGO:200123630.057
nucleic acid templated transcriptionGO:00976591810.056
Mouse
deathGO:00162651210.055
cognitionGO:005089010.055
positive regulation of cell adhesionGO:004578510.054
hemopoiesisGO:00300971830.054
positive regulation of transportGO:005105020.054
muscle fiber developmentGO:0048747520.052
digestive system developmentGO:00551232890.052
immune system developmentGO:00025201910.051
positive regulation of cellular component biogenesisGO:004408930.051
protein metabolic processGO:00195381830.050
Zebrafish
taxisGO:00423301090.050
peptidyl serine phosphorylationGO:001810510.050
cellular component assemblyGO:00226071700.049
growthGO:00400071740.049
Zebrafish
oxoacid metabolic processGO:0043436310.049
Zebrafish
organic cyclic compound metabolic processGO:19013603010.049
Mouse
cellular macromolecule biosynthetic processGO:00346452240.049
Mouse
cell projection morphogenesisGO:00488582440.048
cellular amino acid metabolic processGO:000652070.048
cell proliferationGO:0008283800.048
negative regulation of macromolecule metabolic processGO:0010605760.048
cellular ketone metabolic processGO:0042180110.048
cell deathGO:00082191210.047
regulation of multicellular organismal developmentGO:20000262230.047
striated muscle cell differentiationGO:00511461290.047
cell migrationGO:00164772370.047
heart developmentGO:00075073130.047
cell motilityGO:00488702440.047
negative regulation of metabolic processGO:0009892860.045
cell fate commitmentGO:0045165990.045
negative regulation of protein phosphorylationGO:000193340.045
apoptotic processGO:00069151160.044
determination of heart left right asymmetryGO:00613711170.044
amine metabolic processGO:000930820.043
positive regulation of gene expressionGO:0010628710.043
Mouse
neuron projection morphogenesisGO:00488121610.043
regulation of transcription dna templatedGO:00063552130.043
Mouse
transcription dna templatedGO:00063511810.042
Mouse
nuclear transportGO:005116940.042
regulation of cellular metabolic processGO:00313233200.042
Mouse
response to stressGO:00069502630.041
tube morphogenesisGO:00352393490.040
regulation of cellular amine metabolic processGO:003323800.040
response to ketoneGO:190165410.039
regulation of cell communicationGO:00106462320.039
regulation of cytoplasmic transportGO:190364940.039
hematopoietic or lymphoid organ developmentGO:00485341910.038
skeletal muscle tissue developmentGO:0007519670.038
embryonic heart tube morphogenesisGO:00031431080.038
determination of bilateral symmetryGO:00098552040.038
organonitrogen compound metabolic processGO:1901564740.038
Zebrafish
regulation of macromolecule biosynthetic processGO:00105562250.038
Mouse
peptidyl serine modificationGO:001820920.038
muscle cell developmentGO:00550011150.038
cellular component biogenesisGO:00440851780.037
homeostatic processGO:00425921420.037
phagocytosisGO:000690930.036
gastrulationGO:00073692080.036
autophagyGO:000691440.036
response to light stimulusGO:0009416460.036
small gtpase mediated signal transductionGO:000726480.036
positive regulation of cell substrate adhesionGO:001081110.035
positive regulation of cellular processGO:00485222010.035
Mouse
muscle structure developmentGO:00610611960.035
cellular response to external stimulusGO:007149620.035
regulation of cellular ketone metabolic processGO:001056570.035
muscle organ developmentGO:00075171010.035
urogenital system developmentGO:0001655970.034
gland developmentGO:00487321430.034
regulation of programmed cell deathGO:00430671010.034
regulation of cell differentiationGO:00455951420.033
glial cell migrationGO:000834730.033
muscle tissue developmentGO:00605371100.033
heart morphogenesisGO:00030071560.033
transmission of nerve impulseGO:0019226190.033
organic substance biosynthetic processGO:19015762890.033
Mouse
cellular component movementGO:00069283350.033
positive regulation of cell deathGO:0010942290.032
regulation of protein targetingGO:190353320.032
brain developmentGO:00074202930.032
multicellular organism growthGO:003526440.032
cell projection organizationGO:00300302840.031
blood vessel morphogenesisGO:00485142160.031
positive regulation of leukocyte migrationGO:000268720.031
synaptic growth at neuromuscular junctionGO:005112420.031
regulation of epithelial cell proliferationGO:005067830.031
regulation of intracellular protein transportGO:003315730.031
neuronal action potentialGO:0019228180.031
macromolecule biosynthetic processGO:00090592270.030
Mouse
regulation of cellular amino acid metabolic processGO:000652100.030
stem cell maintenanceGO:001982740.030
negative regulation of cell communicationGO:0010648960.030
system processGO:00030081850.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.030
positive regulation of macromolecule metabolic processGO:0010604930.030
Mouse
epithelial tube morphogenesisGO:00605621480.029
myelinationGO:0042552180.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
Mouse
negative regulation of protein kinase activityGO:000646940.029
myotube cell developmentGO:0014904350.029
neurological system processGO:0050877620.029
negative regulation of protein transportGO:005122430.029
regulation of neurogenesisGO:0050767870.028
biosynthetic processGO:00090582940.028
Mouse
cell surface receptor signaling pathwayGO:00071663250.028
nucleocytoplasmic transportGO:000691340.027
eye developmentGO:00016542770.027
developmental growthGO:00485891660.027
Zebrafish
positive regulation of cell cycleGO:004578730.027
response to carbohydrateGO:000974330.026
regulation of cell cycleGO:0051726520.026
lipid storageGO:001991510.026
positive regulation of apoptotic signaling pathwayGO:200123510.025
phosphate containing compound metabolic processGO:00067961080.025
positive regulation of wound healingGO:009030310.025
regulation of nucleocytoplasmic transportGO:004682220.025
cellular protein metabolic processGO:00442671290.025
skeletal system morphogenesisGO:00487051020.025
regulation of nervous system developmentGO:0051960900.025
regulation of dendrite developmentGO:005077330.024
cellular protein modification processGO:00064641000.024
response to abiotic stimulusGO:00096281220.024
germ line stem cell maintenanceGO:003071820.024
establishment of protein localization to plasma membraneGO:009000210.024
negative regulation of signalingGO:0023057960.024
small molecule metabolic processGO:0044281770.024
Zebrafish
cellular macromolecule metabolic processGO:00442603910.024
Zebrafish Mouse
developmental growth involved in morphogenesisGO:0060560860.023
Zebrafish
heterocycle biosynthetic processGO:00181302150.023
Mouse
transportGO:00068102200.023
phosphorylationGO:0016310690.023
lateral inhibitionGO:004633110.023
cellular response to nutrient levelsGO:003166920.023
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.023
adult behaviorGO:003053420.023
response to chemicalGO:00422213200.023
Rat
regulation of reproductive processGO:200024140.022
cellular response to reactive oxygen speciesGO:003461420.022
regulation of dna replicationGO:000627530.022
organelle organizationGO:00069962270.022
negative regulation of apoptotic processGO:0043066550.021
regulation of cell matrix adhesionGO:000195210.021
regulation of calcium ion transportGO:005192420.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.021
positive regulation of cytokine productionGO:000181920.021
regulation of cell activationGO:005086510.021
maintenance of locationGO:005123540.021
extrinsic apoptotic signaling pathwayGO:009719130.021
negative regulation of cell deathGO:0060548600.021
positive regulation of metabolic processGO:00098931080.021
Mouse
mesenchymal cell proliferationGO:001046310.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.020
locomotionGO:00400113130.020
negative regulation of kinase activityGO:003367340.020
localization of cellGO:00516742440.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
Mouse
response to hexoseGO:000974630.020
cell morphogenesis involved in differentiationGO:00009041950.020
cellular response to topologically incorrect proteinGO:003596720.020
response to uvGO:000941130.020
negative regulation of cytoplasmic transportGO:190365020.020
negative regulation of gene expressionGO:0010629650.020
regulation of protein import into nucleusGO:004230620.020
regulation of cell deathGO:00109411030.019
negative regulation of cytokine productionGO:000181810.019
positive regulation of stem cell proliferationGO:200064810.019
regulation of rna metabolic processGO:00512522240.019
Mouse
protein dephosphorylationGO:000647030.019
action potentialGO:0001508190.019
myeloid cell differentiationGO:0030099860.019
negative regulation of cellular biosynthetic processGO:0031327550.019
protein localization to nucleusGO:003450430.019
axon developmentGO:00615641660.018
response to nutrientGO:000758430.018
heart processGO:0003015710.018
protein homooligomerizationGO:005126030.018
ameboidal type cell migrationGO:00016671430.018
granulocyte migrationGO:0097530110.018
negative regulation of cellular metabolic processGO:0031324770.018
regulation of cell proliferationGO:0042127370.018
regulation of synapse organizationGO:005080730.018
cell adhesionGO:0007155400.018
leukocyte migrationGO:0050900150.018
positive regulation of rna metabolic processGO:0051254590.018
Mouse
cell cycleGO:0007049930.018
positive regulation of cellular biosynthetic processGO:0031328680.018
Mouse
regulation of anatomical structure morphogenesisGO:00226031300.018
multi organism processGO:00517041340.017
chemotaxisGO:00069351040.017
negative regulation of multicellular organismal processGO:0051241690.017
regulation of protein metabolic processGO:0051246560.017
single organism localizationGO:19025782250.017
regulation of protein complex assemblyGO:004325430.017
response to monosaccharideGO:003428430.017
single organism nuclear importGO:190259330.017
regulation of cellular component organizationGO:0051128860.017
ras protein signal transductionGO:000726570.017
neuron projection developmentGO:00311751800.017
positive regulation of response to stimulusGO:0048584800.017
regulation of cytokine productionGO:000181730.017
homeostasis of number of cellsGO:0048872620.017
gtp metabolic processGO:004603940.017
biological adhesionGO:0022610400.017
regulation of metal ion transportGO:001095940.017
embryo development ending in birth or egg hatchingGO:00097922710.017
organelle assemblyGO:00709251100.017
positive regulation of mesenchymal cell proliferationGO:000205310.016
negative regulation of signal transductionGO:0009968940.016
cell cycle g1 s phase transitionGO:004484310.016
negative regulation of dna metabolic processGO:005105340.016
skeletal muscle fiber developmentGO:0048741350.016
locomotor rhythmGO:004547530.016
axon extensionGO:0048675450.016
protein targeting to nucleusGO:004474430.016
axonogenesisGO:00074091520.016
regulation of rho protein signal transductionGO:003502320.016
regulation of reactive oxygen species metabolic processGO:200037720.016
regulation of protein catabolic processGO:004217610.016
striated muscle tissue developmentGO:00147061100.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
guanosine containing compound metabolic processGO:190106840.016
negative regulation of cell differentiationGO:0045596460.016
positive regulation of cellular metabolic processGO:0031325940.015
Mouse
negative regulation of biosynthetic processGO:0009890550.015
positive regulation of catabolic processGO:000989640.015
regulation of biological qualityGO:00650082630.015
g1 s transition of mitotic cell cycleGO:000008210.015
cellular response to chemical stimulusGO:00708871570.015
adherens junction organizationGO:003433240.015
regulation of neural precursor cell proliferationGO:200017730.015
regulation of membrane potentialGO:0042391230.015
guanosine containing compound catabolic processGO:190106920.015
camera type eye developmentGO:00430102220.015
regulation of proteolysisGO:0030162240.015
peptidyl threonine modificationGO:001821010.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
Mouse
positive regulation of map kinase activityGO:004340630.015
positive regulation of cellular catabolic processGO:003133130.015
positive regulation of cellular component movementGO:0051272110.015
response to glucoseGO:000974930.015
regulation of molecular functionGO:0065009700.015
response to corticosteroidGO:003196010.015
protein secretionGO:000930610.015
regulation of cell migrationGO:0030334400.015
protein localization to plasma membraneGO:007265910.015
heart loopingGO:0001947940.015
negative regulation of ras protein signal transductionGO:004658010.015
striated muscle cell developmentGO:00550021080.015
multicellular organismal macromolecule metabolic processGO:004425920.015
behaviorGO:0007610740.015
regulation of multicellular organism growthGO:004001440.015
sensory organ morphogenesisGO:00905962000.015
tissue remodelingGO:004877140.014
regulation of response to external stimulusGO:0032101310.014
protein phosphorylationGO:0006468470.014
cell part morphogenesisGO:00329902460.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
cell morphogenesisGO:00009022890.014
establishment of localization in cellGO:0051649770.014
negative regulation of programmed cell deathGO:0043069580.014
response to glucocorticoidGO:005138410.014
neuron projection extensionGO:1990138450.014
gtp catabolic processGO:000618420.014
mitochondrion organizationGO:000700540.014
determination of left right symmetryGO:00073681790.014
ensheathment of neuronsGO:0007272180.013
regulation of growthGO:0040008420.013
negative regulation of response to stimulusGO:00485851040.013
head developmentGO:00603223030.013
cell substrate junction assemblyGO:000704420.013
positive regulation of apoptotic processGO:0043065290.013
regulation of collagen metabolic processGO:001071220.013
regulation of organelle organizationGO:0033043290.013
spermatid differentiationGO:004851520.013
phosphorus metabolic processGO:00067931090.013
negative regulation of transcription dna templatedGO:0045892450.013
embryonic heart tube developmentGO:00350501330.013
regulation of cellular protein catabolic processGO:190336210.013
circulatory system processGO:0003013870.013
glucose homeostasisGO:004259310.013
rho protein signal transductionGO:000726650.013
single organism biosynthetic processGO:0044711710.013
nuclear importGO:005117030.013
regulation of bmp signaling pathwayGO:0030510390.013
positive regulation of leukocyte chemotaxisGO:000269010.013
liver developmentGO:0001889960.013
membrane invaginationGO:001032410.013
regulation of phosphorus metabolic processGO:0051174430.013
axon ensheathmentGO:0008366180.012
regulation of catalytic activityGO:0050790550.012
skeletal system developmentGO:00015011810.012
Zebrafish Rat
positive regulation of epithelial cell proliferationGO:005067910.012
response to alcoholGO:0097305140.012
establishment of localizationGO:00512342440.012
photoreceptor cell differentiationGO:0046530550.012
regulation of transportGO:0051049450.012
meiotic cell cycle processGO:190304630.012
negative regulation of mapk cascadeGO:004340940.012
negative regulation of small gtpase mediated signal transductionGO:005105810.012
regulation of synapse assemblyGO:005196330.012
spermatid developmentGO:000728620.012
cellular respirationGO:004533330.012
myeloid leukocyte migrationGO:0097529120.012
regulation of carbohydrate metabolic processGO:000610940.012
single organism transportGO:00447652060.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
positive regulation of cellular amine metabolic processGO:003324000.012
cell projection assemblyGO:0030031640.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
Mouse
response to oxygen levelsGO:0070482250.011
response to alkaloidGO:004327920.011
positive regulation of cell activationGO:005086710.011
response to oxygen containing compoundGO:1901700550.011
positive regulation of epithelial cell migrationGO:001063420.011
bmp signaling pathwayGO:0030509520.011
angiogenesisGO:00015251580.011
apoptotic signaling pathwayGO:0097190230.011
negative regulation of dna replicationGO:000815620.011
positive regulation of neutrophil migrationGO:190262400.011
macromolecule modificationGO:00434121110.011
positive regulation of cytoskeleton organizationGO:005149530.011
positive regulation of lipid metabolic processGO:004583410.011
protein importGO:001703830.011
regulation of protein polymerizationGO:003227120.011
gliogenesisGO:0042063450.011
renal system developmentGO:0072001940.011
response to vitaminGO:003327330.011
negative regulation of cellular processGO:00485232830.011
protein acylationGO:004354330.011
negative regulation of developmental processGO:0051093650.011
cellular response to starvationGO:000926710.011
carbohydrate homeostasisGO:003350010.011
heart contractionGO:0060047710.011
regulation of cell developmentGO:00602841000.011
stem cell differentiationGO:00488631170.011
central nervous system developmentGO:00074173870.011
lipid biosynthetic processGO:0008610220.011
response to inorganic substanceGO:0010035380.011
positive regulation of cell migrationGO:0030335110.011
response to hydrogen peroxideGO:004254230.010
eye morphogenesisGO:00485921440.010
establishment of protein localization to organelleGO:007259440.010
peptidyl threonine phosphorylationGO:001810710.010
regulation of gtpase activityGO:004308720.010
stem cell divisionGO:001714510.010
cell growthGO:0016049570.010
positive regulation of multicellular organismal processGO:0051240520.010
regulation of myotube differentiationGO:001083020.010
camera type eye morphogenesisGO:00485931080.010
metal ion transportGO:0030001580.010
myeloid cell homeostasisGO:0002262560.010

lum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.020
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010