Danio rerio

0 known processes

pdzk1

PDZ domain containing 1

(Aliases: wu:fb65e01,wu:fa55e12,pdzk1l,cb1074)

pdzk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inorganic cation transmembrane transportGO:0098662500.777
monovalent inorganic cation transportGO:0015672420.685
ion transmembrane transportGO:0034220910.633
sulfate transmembrane transportGO:190235820.592
ion transportGO:00068111140.573
Mouse
cation transmembrane transportGO:0098655650.567
transmembrane transportGO:00550851200.533
anion transportGO:0006820380.499
Mouse
chloride transportGO:000682180.489
metal ion transportGO:0030001580.484
sodium ion transportGO:0006814240.453
inorganic anion transportGO:0015698250.423
organic anion transportGO:0015711150.416
sodium ion transmembrane transportGO:0035725210.414
cation transportGO:0006812810.378
single organism localizationGO:19025782250.336
Zebrafish Mouse
inorganic ion transmembrane transportGO:0098660570.324
anion transmembrane transportGO:0098656120.292
sulfur compound transportGO:007234830.251
single organism transportGO:00447652060.224
Zebrafish Mouse
response to carbohydrateGO:000974330.223
chloride transmembrane transportGO:190247640.214
transportGO:00068102200.213
Zebrafish Mouse
dicarboxylic acid transportGO:000683510.183
response to drugGO:004249330.171
sulfate transportGO:000827220.151
nitrogen compound metabolic processGO:00068073190.150
bicarbonate transportGO:001570140.149
synaptic transmission cholinergicGO:000727140.146
peptide transportGO:001583310.140
establishment of localizationGO:00512342440.139
Zebrafish Mouse
kidney developmentGO:0001822920.133
regulation of biological qualityGO:00650082630.123
Zebrafish
gastrulationGO:00073692080.108
larval developmentGO:000216420.108
agingGO:000756820.104
Worm
oxalate transportGO:001953210.101
immune system processGO:00023762410.098
developmental growthGO:00485891660.096
nucleobase containing compound biosynthetic processGO:00346542050.090
renal system developmentGO:0072001940.089
homeostatic processGO:00425921420.088
Zebrafish
amide transportGO:0042886120.082
intestinal absorptionGO:005089220.082
hemopoiesisGO:00300971830.081
hormone secretionGO:004687920.081
response to salt stressGO:0009651100.080
digestive system developmentGO:00551232890.078
lipid storageGO:001991510.077
embryonic organ morphogenesisGO:00485622740.076
signal transductionGO:00071654550.076
neuron neuron synaptic transmissionGO:000727010.075
growthGO:00400071740.074
regulation of stem cell differentiationGO:200073640.072
digestive system processGO:002260090.072
maintenance of locationGO:005123540.071
generation of neuronsGO:00486993850.067
i kappab kinase nf kappab signalingGO:000724940.063
xenobiotic metabolic processGO:000680540.062
regulation of multicellular organismal developmentGO:20000262230.061
heterocycle biosynthetic processGO:00181302150.061
response to arsenic containing substanceGO:004668550.060
epibolyGO:0090504410.059
positive regulation of biological processGO:00485182530.059
Mouse
inorganic anion transmembrane transportGO:0098661100.058
regulation of protein complex assemblyGO:004325430.057
organic cyclic compound metabolic processGO:19013603010.055
cell substrate adhesionGO:003158940.055
response to abiotic stimulusGO:00096281220.054
organic substance transportGO:0071702580.054
Zebrafish Mouse
cellular nitrogen compound metabolic processGO:00346412900.050
semicircular canal developmentGO:0060872240.050
developmental growth involved in morphogenesisGO:0060560860.049
nucleobase containing compound metabolic processGO:00061392740.049
neuron developmentGO:00486662620.048
photoreceptor cell differentiationGO:0046530550.048
appendage developmentGO:0048736800.047
immune system developmentGO:00025201910.046
regulation of cell communicationGO:00106462320.046
hepaticobiliary system developmentGO:0061008980.046
protein importGO:001703830.046
establishment of protein localization to organelleGO:007259440.045
negative regulation of protein phosphorylationGO:000193340.043
regulation of multicellular organism growthGO:004001440.042
digestive tract developmentGO:00485652650.042
positive regulation of transportGO:005105020.041
Mouse
response to hexoseGO:000974630.041
rhombomere 5 developmentGO:002157140.041
aromatic compound biosynthetic processGO:00194382170.040
digestive tract morphogenesisGO:00485462310.040
urogenital system developmentGO:0001655970.040
ion homeostasisGO:0050801410.040
Zebrafish
embryonic organ developmentGO:00485683810.039
regulation of cellular macromolecule biosynthetic processGO:20001122220.039
hematopoietic or lymphoid organ developmentGO:00485341910.039
positive regulation of nitrogen compound metabolic processGO:0051173690.039
developmental programmed cell deathGO:001062340.038
erythrocyte homeostasisGO:0034101550.038
cellular nitrogen compound biosynthetic processGO:00442712180.038
endoderm developmentGO:0007492490.037
intrahepatic bile duct developmentGO:0035622110.037
convergent extensionGO:00600261180.036
transcription dna templatedGO:00063511810.036
amino acid transportGO:000686520.035
neuron differentiationGO:00301823530.035
response to monosaccharideGO:003428430.035
inner ear morphogenesisGO:0042472630.034
regionalizationGO:00030022740.034
regulation of i kappab kinase nf kappab signalingGO:004312240.034
response to chemicalGO:00422213200.033
response to glucoseGO:000974930.033
sensory organ developmentGO:00074233930.033
mitochondrion organizationGO:000700540.033
axis elongationGO:0003401310.033
regulation of membrane potentialGO:0042391230.032
stem cell maintenanceGO:001982740.032
single organism metabolic processGO:00447102170.032
carboxylic acid transportGO:004694280.032
triglyceride homeostasisGO:007032820.032
regulation of establishment of protein localizationGO:007020140.032
Mouse
nitrogen compound transportGO:0071705230.032
regulation of developmental processGO:00507932470.032
convergent extension involved in gastrulationGO:0060027710.031
somitogenesisGO:0001756870.031
regulation of cytoplasmic transportGO:190364940.031
mesenchymal cell differentiationGO:0048762870.031
epithelial cell developmentGO:0002064420.031
organic cyclic compound biosynthetic processGO:19013622230.031
hydrogen transportGO:000681870.030
regulation of transcription dna templatedGO:00063552130.030
adherens junction organizationGO:003433240.030
lipid oxidationGO:003444010.030
cellular component maintenanceGO:004395430.030
brain developmentGO:00074202930.029
positive regulation of transcription dna templatedGO:0045893570.029
adult behaviorGO:003053420.028
nucleic acid metabolic processGO:00903042440.028
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.028
regulation of neurotransmitter secretionGO:004692810.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
regulation of multicellular organismal processGO:00512392770.028
regulation of metal ion transportGO:001095940.028
oligopeptide transportGO:000685710.027
neurotransmitter secretionGO:000726920.027
glucose homeostasisGO:004259310.027
regulation of blood vessel sizeGO:005088020.027
myeloid cell differentiationGO:0030099860.027
epithelial tube morphogenesisGO:00605621480.027
cartilage developmentGO:0051216960.027
embryonic hemopoiesisGO:0035162530.026
protein localization to nucleusGO:003450430.026
apoptotic process involved in developmentGO:190274220.026
embryonic digestive tract developmentGO:004856640.026
stem cell differentiationGO:00488631170.026
regulation of rna metabolic processGO:00512522240.026
organic acid metabolic processGO:0006082310.026
cellular biosynthetic processGO:00442492860.026
protein import into nucleusGO:000660630.026
pigment cell developmentGO:007028530.025
negative regulation of stem cell differentiationGO:200073720.025
positive regulation of i kappab kinase nf kappab signalingGO:004312330.025
cellular component morphogenesisGO:00329893360.025
epidermis developmentGO:0008544480.025
positive regulation of cellular component biogenesisGO:004408930.025
regulation of metabolic processGO:00192223590.025
nuclear importGO:005117030.025
polarized epithelial cell differentiationGO:003085940.025
nucleocytoplasmic transportGO:000691340.025
tube morphogenesisGO:00352393490.025
hormone transportGO:000991420.025
calcium ion transport into cytosolGO:006040230.025
amine metabolic processGO:000930820.025
regulation of protein localization to nucleusGO:190018020.025
cellular component assemblyGO:00226071700.024
gastrulation with mouth forming secondGO:0001702440.024
regulation of protein catabolic processGO:004217610.024
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.024
negative regulation of protein kinase activityGO:000646940.024
carbohydrate transportGO:0008643130.024
epithelial cell differentiationGO:00308551160.024
regulation of macromolecule metabolic processGO:00602553170.024
positive regulation of cellular processGO:00485222010.024
inositol lipid mediated signalingGO:004801720.024
regulation of epithelial cell proliferationGO:005067830.024
morphogenesis of an epitheliumGO:00020093330.023
cell migrationGO:00164772370.023
phagocytosisGO:000690930.023
cellular amine metabolic processGO:004410620.023
regulation of intracellular protein transportGO:003315730.023
Mouse
embryonic digestive tract morphogenesisGO:004855730.023
inner ear receptor cell developmentGO:0060119200.023
regulation of neurotransmitter transportGO:005158810.023
acylglycerol homeostasisGO:005509020.023
protein localization to plasma membraneGO:007265910.023
Mouse
cilium morphogenesisGO:0060271850.023
cell deathGO:00082191210.023
macromolecule biosynthetic processGO:00090592270.023
pronephros developmentGO:0048793690.022
regulation of cell deathGO:00109411030.022
type b pancreatic cell developmentGO:000332340.022
cellular component biogenesisGO:00440851780.022
response to stressGO:00069502630.022
regulation of cellular ketone metabolic processGO:001056570.022
cellular component disassemblyGO:002241110.022
regulation of carbohydrate metabolic processGO:000610940.022
positive regulation of macromolecule metabolic processGO:0010604930.022
deathGO:00162651210.021
regulation of cellular amino acid metabolic processGO:000652100.021
synaptic growth at neuromuscular junctionGO:005112420.021
organic substance biosynthetic processGO:19015762890.021
rna metabolic processGO:00160702190.021
proton transportGO:001599270.021
system processGO:00030081850.021
liver developmentGO:0001889960.021
water homeostasisGO:003010440.020
somatic stem cell maintenanceGO:003501910.020
inner ear receptor cell differentiationGO:0060113290.020
locomotionGO:00400113130.020
cellular component movementGO:00069283350.020
multicellular organism growthGO:003526440.020
gland developmentGO:00487321430.020
homeostasis of number of cellsGO:0048872620.020
positive regulation of blood circulationGO:190352420.020
cellular protein catabolic processGO:004425740.020
response to woundingGO:00096111160.020
regulation of nucleocytoplasmic transportGO:004682220.020
actin polymerization or depolymerizationGO:000815420.020
regulation of protein polymerizationGO:003227120.020
negative regulation of mapk cascadeGO:004340940.020
renal tubule morphogenesisGO:006133310.020
long chain fatty acid metabolic processGO:000167610.019
secondary metabolic processGO:001974830.019
macromolecular complex assemblyGO:0065003350.019
cell matrix adhesionGO:000716040.019
protein complex disassemblyGO:004324110.019
regulation of blood pressureGO:000821710.019
heterocycle metabolic processGO:00464832900.019
keratinocyte differentiationGO:003021600.019
phosphatidylinositol mediated signalingGO:004801520.019
modification dependent macromolecule catabolic processGO:004363230.019
lipid catabolic processGO:001604240.019
organonitrogen compound metabolic processGO:1901564740.019
cell projection organizationGO:00300302840.019
adherens junction maintenanceGO:003433420.019
nucleic acid templated transcriptionGO:00976591810.019
regulation of tube sizeGO:003515020.019
neural crest cell migrationGO:0001755420.018
determination of left right symmetryGO:00073681790.018
transcription from rna polymerase ii promoterGO:0006366800.018
skeletal system developmentGO:00015011810.018
carbohydrate homeostasisGO:003350010.018
regulation of cell activationGO:005086510.018
regulation of signalingGO:00230512350.018
regulation of protein transportGO:005122330.018
Mouse
fin morphogenesisGO:0033334530.018
nuclear transportGO:005116940.018
erythrocyte differentiationGO:0030218540.018
single organism nuclear importGO:190259330.018
positive regulation of immune effector processGO:000269930.018
proteasomal protein catabolic processGO:001049820.018
establishment of epithelial cell apical basal polarityGO:004519820.018
modification dependent protein catabolic processGO:001994130.018
positive regulation of secretionGO:005104710.017
regulation of cellular amine metabolic processGO:003323800.017
lipid homeostasisGO:005508830.017
regulation of rna biosynthetic processGO:20011412130.017
ubiquitin dependent protein catabolic processGO:000651130.017
production of molecular mediator of immune responseGO:000244020.017
neural crest cell differentiationGO:0014033720.017
nephron epithelium morphogenesisGO:007208810.017
membrane fusionGO:006102520.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
antimicrobial humoral responseGO:001973020.017
epiboly involved in gastrulation with mouth forming secondGO:0055113350.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
neurotransmitter transportGO:000683620.017
apoptotic process involved in morphogenesisGO:006056120.017
regulation of circadian rhythmGO:004275240.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
biosynthetic processGO:00090582940.017
regulation of nitrogen compound metabolic processGO:00511712510.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
chordate embryonic developmentGO:00430092710.017
regulation of cell differentiationGO:00455951420.017
regulation of protein import into nucleusGO:004230620.017
regulation of macromolecule biosynthetic processGO:00105562250.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
regulation of bindingGO:005109830.017
tyrosine phosphorylation of stat proteinGO:000726010.016
protein targeting to nucleusGO:004474430.016
intracellular signal transductionGO:0035556850.016
cellular amino acid metabolic processGO:000652070.016
positive regulation of metabolic processGO:00098931080.016
regulation of cytokine productionGO:000181730.016
positive regulation of catabolic processGO:000989640.016
fluid transportGO:0042044170.016
positive regulation of cellular catabolic processGO:003133130.016
organic acid transportGO:001584990.016
regulation of reproductive processGO:200024140.016
axis elongation involved in somitogenesisGO:009024520.016
hair cell differentiationGO:0035315320.016
pancreas developmentGO:0031016840.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
positive regulation of macromolecule biosynthetic processGO:0010557590.016
negative regulation of kinase activityGO:003367340.016
negative regulation of macromolecule metabolic processGO:0010605760.016
inner ear developmentGO:00488391260.016
b cell activationGO:004211320.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
macromolecular complex disassemblyGO:003298410.015
extracellular structure organizationGO:0043062270.015
guanosine containing compound metabolic processGO:190106840.015
regulation of calcium ion transportGO:005192420.015
toxin transportGO:190199820.015
carboxylic acid metabolic processGO:0019752220.015
retina morphogenesis in camera type eyeGO:0060042790.015
protein polymerizationGO:005125840.015
stem cell proliferationGO:007208940.015
small molecule metabolic processGO:0044281770.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
programmed cell deathGO:00125011190.015
protein depolymerizationGO:005126110.015
positive regulation of gene expressionGO:0010628710.015
regulation of protein complex disassemblyGO:004324410.015
pigment cell differentiationGO:0050931380.015
response to metal ionGO:0010038340.015
eye photoreceptor cell differentiationGO:0001754450.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
nephric duct morphogenesisGO:007217870.015
regulation of gene expressionGO:00104682650.014
circulatory system processGO:0003013870.014
heart loopingGO:0001947940.014
cellular amide metabolic processGO:004360340.014
regulation of production of molecular mediator of immune responseGO:000270010.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
regulation of cellular biosynthetic processGO:00313262450.014
cellular response to external stimulusGO:007149620.014
chemosensory behaviorGO:000763510.014
somite developmentGO:0061053960.014
spermatid differentiationGO:004851520.014
cell morphogenesis involved in differentiationGO:00009041950.014
cytokinesisGO:000091030.014
endocrine processGO:005088620.014
regulation of cell substrate adhesionGO:001081010.014
neuron migrationGO:0001764220.014
negative regulation of protein transportGO:005122430.014
mesendoderm developmentGO:0048382100.014
exocytosisGO:000688710.014
cellular response to chemical stimulusGO:00708871570.014
superoxide metabolic processGO:000680120.014
cellular protein complex disassemblyGO:004362410.014
protein metabolic processGO:00195381830.014
cellular process involved in reproduction in multicellular organismGO:0022412280.014
otic vesicle developmentGO:0071599420.014
protein complex biogenesisGO:0070271300.014
regulation of muscle contractionGO:000693730.014
cell part morphogenesisGO:00329902460.014
regulation of carbohydrate biosynthetic processGO:004325510.014
epidermal cell differentiationGO:0009913360.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
negative regulation of metabolic processGO:0009892860.014
cell motilityGO:00488702440.014
regulation of primary metabolic processGO:00800903110.014
calcium ion importGO:007050940.013
regulation of protein depolymerizationGO:190187910.013
cell junction maintenanceGO:003433120.013
oxoacid metabolic processGO:0043436310.013
nephron morphogenesisGO:007202820.013
protein complex assemblyGO:0006461300.013
mesenchymal cell developmentGO:0014031780.013
negative regulation of cytoplasmic transportGO:190365020.013
cellular ketone metabolic processGO:0042180110.013
actin filament polymerizationGO:003004120.013
cellular response to nutrient levelsGO:003166920.013
guanosine containing compound catabolic processGO:190106920.013
positive regulation of jak stat cascadeGO:004642720.013
regulation of biosynthetic processGO:00098892500.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
semicircular canal morphogenesisGO:0048752180.013
specification of symmetryGO:00097992040.013
skin developmentGO:0043588540.013
cytosolic calcium ion transportGO:006040130.013
negative regulation of response to stimulusGO:00485851040.013
connective tissue developmentGO:0061448990.013
skeletal system morphogenesisGO:00487051020.013
cellular response to starvationGO:000926710.013
regulation of reactive oxygen species metabolic processGO:200037720.013
response to organic substanceGO:00100331530.013
sequestering of metal ionGO:005123830.013
hindbrain developmentGO:0030902910.013
positive regulation of cell cycleGO:004578730.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
common bile duct developmentGO:0061009130.013
endocrine hormone secretionGO:006098620.013
negative regulation of cellular metabolic processGO:0031324770.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
photoreceptor cell developmentGO:0042461400.012
gtp catabolic processGO:000618420.012
meiotic cell cycle processGO:190304630.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
alpha amino acid metabolic processGO:190160530.012
axon developmentGO:00615641660.012
blood circulationGO:0008015870.012
cellular macromolecule biosynthetic processGO:00346452240.012
single organism membrane fusionGO:004480120.012
cellular response to xenobiotic stimulusGO:0071466350.012
release of sequestered calcium ion into cytosolGO:005120930.012
regulation of nucleoside metabolic processGO:000911820.012
organelle organizationGO:00069962270.012
positive regulation of carbohydrate metabolic processGO:004591310.012
auditory receptor cell morphogenesisGO:000209340.012
heart joggingGO:0003146400.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
gene expressionGO:00104672520.012
neuron projection developmentGO:00311751800.012
protein acetylationGO:000647320.012
regulation of response to stimulusGO:00485832690.012
lymphocyte proliferationGO:004665110.012
regulation of epidermis developmentGO:004568220.012
regulation of sodium ion transmembrane transportGO:190230510.012
rhombomere 6 developmentGO:002157240.012
pronephros morphogenesisGO:0072114140.012
action potentialGO:0001508190.012
regulation of protein ubiquitinationGO:003139630.012
cell morphogenesisGO:00009022890.012
pigmentationGO:0043473850.012
regulation of apoptotic processGO:0042981980.012
stem cell developmentGO:0048864820.012
ear developmentGO:00435831270.012
b cell differentiationGO:003018310.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
peptidyl lysine acetylationGO:001839420.012
response to hydrogen peroxideGO:004254230.012
leukocyte proliferationGO:007066110.012
negative regulation of signal transductionGO:0009968940.012
negative regulation of biological processGO:00485193040.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
anterior posterior pattern specificationGO:00099521520.011
endothelial cell fate commitmentGO:006083930.011
regulation of dendrite developmentGO:005077330.011
lymphatic endothelial cell differentiationGO:006083610.011
sensory perception of chemical stimulusGO:000760630.011
chemical homeostasisGO:0048878490.011
Zebrafish
response to nutrientGO:000758430.011
peptide metabolic processGO:000651810.011
nucleoside monophosphate catabolic processGO:000912540.011
regulation of jak stat cascadeGO:004642530.011
nephric duct developmentGO:0072176130.011
regulation of cellular protein catabolic processGO:190336210.011
positive regulation of cytoskeleton organizationGO:005149530.011
spermatid developmentGO:000728620.011
regulation of cell shapeGO:000836010.011
positive regulation of cell activationGO:005086710.011
regulation of systemic arterial blood pressureGO:000307310.011
negative regulation of signalingGO:0023057960.011
positive regulation of leukocyte differentiationGO:190210710.011
cellular response to biotic stimulusGO:007121630.011
regulation of sequestering of calcium ionGO:005128240.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of signal transductionGO:00099662250.011
regulation of blood coagulationGO:003019310.011
regulation of sodium ion transmembrane transporter activityGO:200064910.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
organelle assemblyGO:00709251100.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of phGO:000688530.011
gtp metabolic processGO:004603940.011
long chain fatty acid transportGO:001590910.011
cell aggregationGO:009874330.011
regulation of gtpase activityGO:004308720.011
internal protein amino acid acetylationGO:000647520.011
formation of primary germ layerGO:0001704620.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
female sex differentiationGO:004666040.011
regulation of nervous system developmentGO:0051960900.011
embryonic heart tube morphogenesisGO:00031431080.011
lateral line system developmentGO:0048925760.011
carbohydrate biosynthetic processGO:001605110.011
fatty acid biosynthetic processGO:000663340.011
tissue regenerationGO:0042246740.011
cellular macromolecule metabolic processGO:00442603910.011
regulation of localizationGO:00328791040.010
Mouse
regulation of transporter activityGO:003240920.010
g protein coupled receptor signaling pathwayGO:0007186740.010
sequestering of calcium ionGO:005120830.010
negative regulation of programmed cell deathGO:0043069580.010
endosomal transportGO:001619720.010

pdzk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.034
cancerDOID:16200.034
disease of cellular proliferationDOID:1456600.034
disease of metabolismDOID:001466700.026
diabetes mellitusDOID:935100.023
type 2 diabetes mellitusDOID:935200.023
acquired metabolic diseaseDOID:006015800.023
glucose metabolism diseaseDOID:419400.023
carbohydrate metabolism diseaseDOID:005001300.023
disease of anatomical entityDOID:700.021
maturity onset diabetes of the youngDOID:005052400.011