Danio rerio

0 known processes

lrwd1

leucine-rich repeats and WD repeat domain containing 1

(Aliases: wu:ft31b04,wu:fb78b03,si:dkey-261j4.9)

lrwd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule metabolic processGO:00442603910.485
organic cyclic compound metabolic processGO:19013603010.476
negative regulation of cellular processGO:00485232830.401
nucleic acid metabolic processGO:00903042440.382
regulation of nucleobase containing compound metabolic processGO:00192192500.365
cellular aromatic compound metabolic processGO:00067252950.307
cellular nitrogen compound metabolic processGO:00346412900.291
nitrogen compound metabolic processGO:00068073190.281
cellular macromolecule biosynthetic processGO:00346452240.281
regulation of nitrogen compound metabolic processGO:00511712510.272
nucleobase containing compound metabolic processGO:00061392740.265
cellular biosynthetic processGO:00442492860.264
regulation of primary metabolic processGO:00800903110.254
heterocycle biosynthetic processGO:00181302150.230
negative regulation of biological processGO:00485193040.227
macromolecule biosynthetic processGO:00090592270.195
organic substance biosynthetic processGO:19015762890.194
meiotic cell cycle processGO:190304630.185
regulation of cellular metabolic processGO:00313233200.175
larval developmentGO:000216420.167
regulation of gene expressionGO:00104682650.167
positive regulation of biological processGO:00485182530.165
nucleic acid templated transcriptionGO:00976591810.163
regulation of metabolic processGO:00192223590.161
gene expressionGO:00104672520.155
single organism organelle organizationGO:19025891990.145
maintenance of locationGO:005123540.143
regulation of cellular biosynthetic processGO:00313262450.143
heterocycle metabolic processGO:00464832900.139
organelle organizationGO:00069962270.129
Human
meiotic nuclear divisionGO:000712640.120
single organism metabolic processGO:00447102170.120
cellular nitrogen compound biosynthetic processGO:00442712180.113
nucleobase containing compound biosynthetic processGO:00346542050.112
transcription dna templatedGO:00063511810.107
response to stressGO:00069502630.105
nucleoside monophosphate catabolic processGO:000912540.105
cell cycleGO:0007049930.104
chromosome organizationGO:0051276310.095
Human
mitotic dna damage checkpointGO:004477340.092
regulation of biosynthetic processGO:00098892500.092
regulation of biological qualityGO:00650082630.089
purine nucleoside monophosphate catabolic processGO:000912840.089
regulation of macromolecule metabolic processGO:00602553170.084
regulation of rna metabolic processGO:00512522240.081
meiosis iGO:000712710.080
regulation of macromolecule biosynthetic processGO:00105562250.080
regulation of nucleic acid templated transcriptionGO:19035062130.078
regulation of transcription dna templatedGO:00063552130.074
regulation of rna biosynthetic processGO:20011412130.073
biosynthetic processGO:00090582940.072
g2 dna damage checkpointGO:003157230.068
aromatic compound biosynthetic processGO:00194382170.068
organic cyclic compound biosynthetic processGO:19013622230.067
rna localizationGO:000640340.066
cytoskeleton organizationGO:0007010960.064
double strand break repair via homologous recombinationGO:000072410.063
organonitrogen compound metabolic processGO:1901564740.062
signal transductionGO:00071654550.060
ribonucleoside monophosphate catabolic processGO:000915840.060
regulation of cellular macromolecule biosynthetic processGO:20001122220.059
multi organism processGO:00517041340.056
negative regulation of metabolic processGO:0009892860.055
negative regulation of nitrogen compound metabolic processGO:0051172590.055
mitotic dna integrity checkpointGO:004477440.054
lipid storageGO:001991510.054
negative regulation of cellular metabolic processGO:0031324770.053
positive regulation of cellular metabolic processGO:0031325940.051
negative regulation of nucleobase containing compound metabolic processGO:0045934590.051
cellular response to stressGO:0033554620.050
regulation of signalingGO:00230512350.047
cellular component biogenesisGO:00440851780.045
protein metabolic processGO:00195381830.045
atp catabolic processGO:000620040.045
single organism reproductive processGO:0044702400.044
negative regulation of gene expressionGO:0010629650.041
negative regulation of transcription dna templatedGO:0045892450.041
rna metabolic processGO:00160702190.040
g1 s transition of mitotic cell cycleGO:000008210.040
negative regulation of mitosisGO:004583930.040
actin filament based processGO:0030029640.039
cellular protein metabolic processGO:00442671290.039
negative regulation of macromolecule metabolic processGO:0010605760.039
carbohydrate derivative metabolic processGO:1901135610.038
agingGO:000756820.038
positive regulation of cell cycleGO:004578730.038
cell cycle g1 s phase transitionGO:004484310.037
cell part morphogenesisGO:00329902460.036
embryo development ending in birth or egg hatchingGO:00097922710.036
purine nucleotide metabolic processGO:0006163270.036
cell cycle processGO:0022402530.035
cellular response to dna damage stimulusGO:0006974240.035
positive regulation of cellular component biogenesisGO:004408930.034
tube morphogenesisGO:00352393490.034
regulation of mrna splicing via spliceosomeGO:004802430.033
internal protein amino acid acetylationGO:000647520.033
regulation of response to stimulusGO:00485832690.033
cellular component assemblyGO:00226071700.033
mitotic recombinationGO:000631220.033
single organism localizationGO:19025782250.032
regulation of meiotic cell cycleGO:005144510.030
macromolecule localizationGO:0033036540.030
Human
regulation of cellular amino acid metabolic processGO:000652100.030
negative regulation of biosynthetic processGO:0009890550.030
regulation of bindingGO:005109830.029
nucleotide metabolic processGO:0009117280.029
neuron differentiationGO:00301823530.029
ribose phosphate metabolic processGO:0019693270.029
purine ribonucleoside monophosphate catabolic processGO:000916940.028
digestive tract developmentGO:00485652650.028
transcription from rna polymerase ii promoterGO:0006366800.028
amine metabolic processGO:000930820.028
multicellular organism growthGO:003526440.027
double strand break repairGO:000630230.027
sequestering of metal ionGO:005123830.027
positive regulation of cellular processGO:00485222010.027
mitotic cell cycle processGO:1903047480.027
protein acylationGO:004354330.026
regulation of dna replicationGO:000627530.026
neuron developmentGO:00486662620.026
response to uvGO:000941130.025
regulation of transcription from rna polymerase ii promoterGO:00063571140.025
regulation of cell communicationGO:00106462320.025
transportGO:00068102200.024
deathGO:00162651210.024
regulation of cellular component organizationGO:0051128860.024
regulation of cell deathGO:00109411030.023
b cell activationGO:004211320.023
cell deathGO:00082191210.023
regulation of cellular amine metabolic processGO:003323800.023
microtubule organizing center organizationGO:003102310.023
regulation of signal transductionGO:00099662250.023
negative regulation of rna metabolic processGO:0051253480.022
protein complex localizationGO:003150310.022
muscle structure developmentGO:00610611960.022
recombinational repairGO:000072510.022
regulation of multicellular organism growthGO:004001440.022
gtp catabolic processGO:000618420.022
negative regulation of nucleic acid templated transcriptionGO:1903507450.022
apoptotic processGO:00069151160.022
regulation of protein complex assemblyGO:004325430.022
cytokinesisGO:000091030.022
sister chromatid cohesionGO:000706220.022
regulation of dna recombinationGO:000001820.022
programmed cell deathGO:00125011190.021
multi organism reproductive processGO:0044703360.021
response to chemicalGO:00422213200.021
positive regulation of catabolic processGO:000989640.021
meiotic chromosome segregationGO:004513230.021
regulation of cellular protein catabolic processGO:190336210.021
telomere organizationGO:003220010.021
rna processingGO:0006396250.021
cellular amino acid metabolic processGO:000652070.021
regulation of cell cycleGO:0051726520.021
cell morphogenesisGO:00009022890.021
cellular amine metabolic processGO:004410620.020
cell surface receptor signaling pathwayGO:00071663250.020
organophosphate metabolic processGO:0019637370.020
regulation of cellular ketone metabolic processGO:001056570.020
microtubule cytoskeleton organization involved in mitosisGO:190285010.020
rna biosynthetic processGO:00327741810.020
mitotic cell cycleGO:0000278640.020
telomere maintenanceGO:000072310.020
dna catabolic processGO:000630810.019
purine containing compound metabolic processGO:0072521290.019
positive regulation of metabolic processGO:00098931080.019
negative regulation of cellular biosynthetic processGO:0031327550.019
female gamete generationGO:0007292140.019
actin cytoskeleton organizationGO:0030036630.019
nuclear divisionGO:0000280230.019
regulation of protein catabolic processGO:004217610.018
cellular protein catabolic processGO:004425740.018
chromosome segregationGO:0007059120.018
muscle organ developmentGO:00075171010.018
regulation of chromosome segregationGO:005198310.018
growthGO:00400071740.018
organelle fissionGO:0048285230.018
digestive system developmentGO:00551232890.018
phosphate containing compound metabolic processGO:00067961080.017
cellular component morphogenesisGO:00329893360.017
multicellular organismal reproductive processGO:0048609350.017
cellular response to radiationGO:007147840.017
positive regulation of cellular catabolic processGO:003133130.017
cell projection morphogenesisGO:00488582440.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
negative regulation of dna metabolic processGO:005105340.017
cell projection organizationGO:00300302840.017
cellular process involved in reproduction in multicellular organismGO:0022412280.017
small molecule metabolic processGO:0044281770.017
immunoglobulin mediated immune responseGO:001606430.017
small gtpase mediated signal transductionGO:000726480.016
establishment of localizationGO:00512342440.016
Human
hatchingGO:003518840.016
guanosine containing compound catabolic processGO:190106920.016
ubiquitin dependent protein catabolic processGO:000651130.016
protein acetylationGO:000647320.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
alternative mrna splicing via spliceosomeGO:000038010.016
reciprocal dna recombinationGO:003582510.016
fertilizationGO:000956630.016
ribonucleotide metabolic processGO:0009259270.016
guanosine containing compound metabolic processGO:190106840.015
negative regulation of kinase activityGO:003367340.015
organism emergence from protective structureGO:007168440.015
production of molecular mediator of immune responseGO:000244020.015
negative regulation of signal transductionGO:0009968940.015
neurological system processGO:0050877620.015
gtp metabolic processGO:004603940.015
phosphorylationGO:0016310690.015
negative regulation of protein phosphorylationGO:000193340.015
protein modification processGO:00362111000.015
negative regulation of response to stimulusGO:00485851040.015
nucleoside phosphate metabolic processGO:0006753280.015
cellular macromolecular complex assemblyGO:0034622240.015
positive regulation of transportGO:005105020.015
cognitionGO:005089010.014
purine ribonucleotide metabolic processGO:0009150270.014
oxoacid metabolic processGO:0043436310.014
generation of neuronsGO:00486993850.014
cellular protein modification processGO:00064641000.014
positive regulation of dna metabolic processGO:005105410.014
regulation of mitotic cell cycleGO:0007346250.014
reproductive processGO:0022414400.014
locomotionGO:00400113130.014
carboxylic acid metabolic processGO:0019752220.014
negative regulation of rna biosynthetic processGO:1902679450.014
modification dependent macromolecule catabolic processGO:004363230.014
regulation of mitotic cell cycle phase transitionGO:190199080.014
cytosolic calcium ion transportGO:006040130.014
sequestering of calcium ionGO:005120830.014
modification dependent protein catabolic processGO:001994130.014
intracellular signal transductionGO:0035556850.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
behaviorGO:0007610740.013
actin polymerization or depolymerizationGO:000815420.013
nuclear exportGO:005116810.013
organelle assemblyGO:00709251100.013
regulation of catalytic activityGO:0050790550.013
g2 m transition of mitotic cell cycleGO:000008640.013
macromolecular complex assemblyGO:0065003350.013
mitotic cell cycle checkpointGO:000709350.013
negative regulation of sequestering of calcium ionGO:005128340.013
macromolecular complex subunit organizationGO:0043933740.012
Human
homeostatic processGO:00425921420.012
regulation of cell cycle phase transitionGO:190198780.012
regulation of sequestering of calcium ionGO:005128240.012
positive regulation of nucleotide catabolic processGO:003081310.012
actomyosin structure organizationGO:0031032530.012
embryonic organ developmentGO:00485683810.012
macromolecule modificationGO:00434121110.012
nucleobase containing compound transportGO:001593120.012
positive regulation of cell communicationGO:0010647560.012
intrinsic apoptotic signaling pathwayGO:0097193200.012
negative regulation of nuclear divisionGO:005178430.012
developmental growthGO:00485891660.012
cell cycle checkpointGO:000007570.011
negative regulation of dna replicationGO:000815620.011
calcium ion transport into cytosolGO:006040230.011
positive regulation of macromolecule metabolic processGO:0010604930.011
meiotic cell cycleGO:005132150.011
mrna export from nucleusGO:000640610.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of nucleoside metabolic processGO:000911820.011
dna integrity checkpointGO:003157060.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
dna metabolic processGO:0006259270.011
protein complex subunit organizationGO:0071822460.011
negative regulation of cell cycle processGO:001094890.011
cellular localizationGO:0051641970.011
Human
regulation of cell cycle processGO:0010564200.011
regulation of programmed cell deathGO:00430671010.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
regulation of purine nucleotide catabolic processGO:003312120.011
establishment of rna localizationGO:005123630.011
negative regulation of mitotic cell cycleGO:0045930110.011
rna export from nucleusGO:000640510.011
regulation of gene silencingGO:006096810.011
cell cycle g2 m phase transitionGO:004483940.010
fatty acid biosynthetic processGO:000663340.010
rna transportGO:005065820.010
cell proliferationGO:0008283800.010
spermatid developmentGO:000728620.010
organic acid metabolic processGO:0006082310.010
sexual reproductionGO:0019953360.010

lrwd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.013
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
inherited metabolic disorderDOID:65500.011