Danio rerio

51 known processes

mfn2

mitofusin 2

(Aliases: si:dkeyp-104h9.2)

mfn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell part morphogenesisGO:00329902460.880
cell projection organizationGO:00300302840.750
neuron projection developmentGO:00311751800.729
nitrogen compound metabolic processGO:00068073190.688
negative regulation of biological processGO:00485193040.662
generation of neuronsGO:00486993850.629
neuron projection morphogenesisGO:00488121610.516
regulation of multicellular organismal developmentGO:20000262230.512
regulation of synapse assemblyGO:005196330.504
regulation of cell projection organizationGO:0031344440.483
regulation of biological qualityGO:00650082630.472
cell morphogenesisGO:00009022890.462
signal transductionGO:00071654550.454
cytoskeleton organizationGO:0007010960.448
cell projection morphogenesisGO:00488582440.441
cellular component movementGO:00069283350.439
cell morphogenesis involved in neuron differentiationGO:00486671630.399
axon developmentGO:00615641660.388
regulation of response to stimulusGO:00485832690.379
muscle cell differentiationGO:00426921390.368
axonogenesisGO:00074091520.361
cellular component morphogenesisGO:00329893360.339
negative regulation of cellular processGO:00485232830.328
agingGO:000756820.318
cellular component assemblyGO:00226071700.315
cellular response to external stimulusGO:007149620.307
regulation of developmental processGO:00507932470.306
regulation of synapse organizationGO:005080730.304
locomotionGO:00400113130.300
regulation of nervous system developmentGO:0051960900.293
axon guidanceGO:0007411860.282
larval developmentGO:000216420.269
regulation of cell shapeGO:000836010.266
response to external stimulusGO:00096052640.256
regulation of axonogenesisGO:0050770320.256
regulation of cellular amino acid metabolic processGO:000652100.249
single organism organelle organizationGO:19025891990.245
negative regulation of cell projection organizationGO:003134590.228
neuron developmentGO:00486662620.218
regulation of neurogenesisGO:0050767870.218
negative regulation of response to stimulusGO:00485851040.211
cell morphogenesis involved in differentiationGO:00009041950.207
regulation of cellular amine metabolic processGO:003323800.202
establishment of localization in cellGO:0051649770.201
cellular carbohydrate metabolic processGO:004426240.201
brain developmentGO:00074202930.195
regulation of cell developmentGO:00602841000.195
cell surface receptor signaling pathwayGO:00071663250.193
regulation of cytoskeleton organizationGO:0051493110.191
regulation of neuron differentiationGO:0045664560.189
regulation of neuron projection developmentGO:0010975400.186
regulation of cell communicationGO:00106462320.186
single organism transportGO:00447652060.181
lateral inhibitionGO:004633110.180
negative regulation of small gtpase mediated signal transductionGO:005105810.179
developmental growth involved in morphogenesisGO:0060560860.177
response to abiotic stimulusGO:00096281220.177
gastrulationGO:00073692080.175
establishment of localizationGO:00512342440.173
single organism intracellular transportGO:1902582250.167
digestive tract developmentGO:00485652650.165
embryonic organ developmentGO:00485683810.162
regulation of autophagyGO:001050630.159
cell motilityGO:00488702440.155
muscle structure developmentGO:00610611960.153
regulation of cell morphogenesis involved in differentiationGO:0010769380.150
cellular component disassemblyGO:002241110.144
axonal defasciculationGO:000741420.142
regulation of cell differentiationGO:00455951420.142
carbohydrate biosynthetic processGO:001605110.141
carbohydrate derivative biosynthetic processGO:1901137430.141
organelle localizationGO:0051640490.140
myofibril assemblyGO:0030239480.139
cellular localizationGO:0051641970.134
muscle cell developmentGO:00550011150.134
cell migration involved in gastrulationGO:0042074790.133
protein metabolic processGO:00195381830.130
embryonic organ morphogenesisGO:00485622740.129
behaviorGO:0007610740.125
regulation of peptidyl tyrosine phosphorylationGO:005073010.123
cellular response to organic substanceGO:00713101050.122
cellular amine metabolic processGO:004410620.121
ameboidal type cell migrationGO:00016671430.120
localization of cellGO:00516742440.120
cellular ketone metabolic processGO:0042180110.119
positive regulation of cellular amino acid metabolic processGO:004576400.119
cellular macromolecule metabolic processGO:00442603910.114
response to hormoneGO:0009725480.114
cellular component biogenesisGO:00440851780.109
striated muscle tissue developmentGO:00147061100.109
regulation of apoptotic processGO:0042981980.108
response to glucocorticoidGO:005138410.108
cation transmembrane transportGO:0098655650.107
regulation of nucleobase containing compound metabolic processGO:00192192500.105
actin cytoskeleton organizationGO:0030036630.104
dendrite developmentGO:001635890.104
neuron projection guidanceGO:0097485860.103
intracellular signal transductionGO:0035556850.103
regulation of bindingGO:005109830.102
calcium ion transmembrane transportGO:0070588130.101
cognitionGO:005089010.100
dendrite morphogenesisGO:004881350.099
single organism localizationGO:19025782250.099
intracellular transportGO:0046907320.098
regulation of protein bindingGO:004339330.097
regulation of metabolic processGO:00192223590.096
cellular biosynthetic processGO:00442492860.095
organelle assemblyGO:00709251100.094
amine metabolic processGO:000930820.094
signal transduction in absence of ligandGO:003803410.094
regulation of signal transductionGO:00099662250.093
cell migrationGO:00164772370.092
regulation of cellular carbohydrate metabolic processGO:001067540.091
protein polymerizationGO:005125840.090
cellular protein modification processGO:00064641000.089
regulation of intracellular protein transportGO:003315730.088
membrane fusionGO:006102520.086
striated muscle cell developmentGO:00550021080.085
regulation of cell morphogenesisGO:0022604420.085
regulation of multicellular organismal processGO:00512392770.084
negative regulation of cell communicationGO:0010648960.084
regulation of cellular ketone metabolic processGO:001056570.084
organic substance transportGO:0071702580.082
regulation of establishment of protein localizationGO:007020140.082
actin filament polymerizationGO:003004120.081
macromolecule modificationGO:00434121110.081
organelle organizationGO:00069962270.080
single organism membrane fusionGO:004480120.079
organic substance biosynthetic processGO:19015762890.079
immune system processGO:00023762410.079
regulation of cell deathGO:00109411030.079
head developmentGO:00603223030.079
cellular response to oxygen containing compoundGO:1901701200.078
synaptic growth at neuromuscular junctionGO:005112420.078
response to light stimulusGO:0009416460.077
positive regulation of transportGO:005105020.077
regulation of dendrite developmentGO:005077330.076
cellular amino acid metabolic processGO:000652070.075
regulation of cell substrate adhesionGO:001081010.075
cell matrix adhesionGO:000716040.075
negative regulation of catabolic processGO:000989530.074
negative regulation of ras protein signal transductionGO:004658010.074
actin polymerization or depolymerizationGO:000815420.074
regulation of cellular metabolic processGO:00313233200.073
protein complex disassemblyGO:004324110.073
central nervous system neuron axonogenesisGO:0021955180.073
organelle fusionGO:004828430.072
small gtpase mediated signal transductionGO:000726480.072
protein localization to plasma membraneGO:007265910.071
regulation of localizationGO:00328791040.070
central nervous system developmentGO:00074173870.069
protein localizationGO:0008104400.069
microtubule depolymerizationGO:000701910.068
chordate embryonic developmentGO:00430092710.068
muscle tissue developmentGO:00605371100.068
membrane organizationGO:0061024210.067
microtubule cytoskeleton organizationGO:0000226330.067
chemosensory behaviorGO:000763510.066
macromolecular complex disassemblyGO:003298410.066
negative regulation of programmed cell deathGO:0043069580.066
negative regulation of signalingGO:0023057960.065
regulation of signalingGO:00230512350.065
mitotic cell cycle processGO:1903047480.065
proteasomal protein catabolic processGO:001049820.064
nucleobase containing compound biosynthetic processGO:00346542050.064
regulation of cellular component organizationGO:0051128860.064
negative regulation of protein transportGO:005122430.064
protein dephosphorylationGO:000647030.063
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.063
organic cyclic compound metabolic processGO:19013603010.063
negative regulation of axon extension involved in axon guidanceGO:004884310.063
positive regulation of cell projection organizationGO:003134690.062
positive regulation of neuron deathGO:190121610.062
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.062
cellular response to extracellular stimulusGO:003166820.062
single organism nuclear importGO:190259330.062
post embryonic organ developmentGO:004856940.062
single organism cellular localizationGO:1902580460.061
protein modification processGO:00362111000.061
heterocycle biosynthetic processGO:00181302150.061
cellular response to chemical stimulusGO:00708871570.060
phosphorylationGO:0016310690.059
developmental growthGO:00485891660.059
peptidyl serine phosphorylationGO:001810510.059
digestive tract morphogenesisGO:00485462310.058
oocyte maturationGO:000155640.058
positive regulation of nervous system developmentGO:0051962250.058
regulation of protein complex assemblyGO:004325430.058
regulation of protein transportGO:005122330.057
epibolyGO:0090504410.057
neurological system processGO:0050877620.057
establishment of organelle localizationGO:0051656450.057
response to endogenous stimulusGO:0009719830.056
heart developmentGO:00075073130.056
actin filament based processGO:0030029640.055
cellular macromolecule biosynthetic processGO:00346452240.055
locomotory behaviorGO:0007626340.055
protein depolymerizationGO:005126110.054
small molecule metabolic processGO:0044281770.054
regulation of macromolecule metabolic processGO:00602553170.053
macromolecule biosynthetic processGO:00090592270.053
response to drugGO:004249330.053
energy reserve metabolic processGO:000611220.053
protein complex biogenesisGO:0070271300.053
compound eye developmentGO:004874920.053
negative regulation of nucleocytoplasmic transportGO:004682320.053
negative regulation of cellular catabolic processGO:003133030.053
maintenance of locationGO:005123540.052
establishment of protein localization to organelleGO:007259440.052
response to chemicalGO:00422213200.052
cell growthGO:0016049570.052
ubiquitin dependent protein catabolic processGO:000651130.052
positive regulation of small gtpase mediated signal transductionGO:005105710.052
neuron differentiationGO:00301823530.051
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.050
system processGO:00030081850.050
regulation of nucleic acid templated transcriptionGO:19035062130.049
synapse assemblyGO:000741690.049
negative regulation of nervous system developmentGO:0051961220.049
regulation of cell migrationGO:0030334400.049
developmental maturationGO:0021700340.049
cell fate specificationGO:0001708680.049
chemotaxisGO:00069351040.048
positive regulation of ras protein signal transductionGO:004657910.048
transportGO:00068102200.047
neuroblast proliferationGO:000740520.047
taxisGO:00423301090.046
cellular response to nutrient levelsGO:003166920.046
regulation of cellular macromolecule biosynthetic processGO:20001122220.046
adult behaviorGO:003053420.046
cellular extravasationGO:004512310.046
regulation of actin filament based processGO:003297090.046
outflow tract morphogenesisGO:000315110.046
exocytosisGO:000688710.045
carbohydrate metabolic processGO:0005975120.045
positive regulation of secretion by cellGO:190353210.045
negative regulation of intracellular transportGO:003238730.045
ras protein signal transductionGO:000726570.045
regulation of multicellular organism growthGO:004001440.045
regulation of transportGO:0051049450.045
single organism behaviorGO:0044708240.044
organic cyclic compound biosynthetic processGO:19013622230.043
rna biosynthetic processGO:00327741810.043
axon extensionGO:0048675450.043
regulation of cellular biosynthetic processGO:00313262450.042
skeletal system developmentGO:00015011810.042
microtubule polymerization or depolymerizationGO:003110930.042
negative regulation of chemotaxisGO:005092240.041
positive regulation of neuron projection developmentGO:001097690.041
glycoprotein biosynthetic processGO:0009101210.041
response to mechanical stimulusGO:0009612240.041
establishment of protein localization to plasma membraneGO:009000210.041
lipid storageGO:001991510.041
protein importGO:001703830.040
regulation of protein localization to nucleusGO:190018020.040
regulation of intracellular signal transductionGO:1902531570.040
leukocyte homeostasisGO:000177620.040
peptidyl threonine phosphorylationGO:001810710.039
response to oxygen radicalGO:000030520.039
heterocycle metabolic processGO:00464832900.039
peptidyl threonine modificationGO:001821010.038
negative regulation of cell deathGO:0060548600.038
cell substrate adhesionGO:003158940.037
protein complex assemblyGO:0006461300.037
cell fate commitmentGO:0045165990.037
positive regulation of cellular metabolic processGO:0031325940.037
organism emergence from protective structureGO:007168440.036
nitric oxide biosynthetic processGO:000680920.036
catabolic processGO:0009056320.036
regulation of metal ion transportGO:001095940.036
regulation of transcription dna templatedGO:00063552130.036
single organismal cell cell adhesionGO:0016337290.036
oxoacid metabolic processGO:0043436310.036
response to corticosteroidGO:003196010.036
regulation of synaptic growth at neuromuscular junctionGO:000858210.035
cellular component assembly involved in morphogenesisGO:00109271070.035
nucleobase containing compound metabolic processGO:00061392740.035
regulation of primary metabolic processGO:00800903110.035
regulation of mitochondrion organizationGO:001082110.035
regulation of cellular component sizeGO:0032535300.035
regulation of establishment of protein localization to plasma membraneGO:009000310.035
negative regulation of signal transductionGO:0009968940.035
regulation of cellular component biogenesisGO:0044087120.034
digestive tract mesoderm developmentGO:000750210.034
detection of external stimulusGO:0009581240.034
regulation of protein import into nucleusGO:004230620.034
anion transportGO:0006820380.034
response to superoxideGO:000030320.034
actin filament organizationGO:0007015150.033
glial cell migrationGO:000834730.033
modification dependent macromolecule catabolic processGO:004363230.033
microtubule organizing center organizationGO:003102310.033
cation homeostasisGO:0055080330.033
regulation of cytoplasmic transportGO:190364940.033
regulation of macromolecule biosynthetic processGO:00105562250.033
g1 s transition of mitotic cell cycleGO:000008210.033
atp catabolic processGO:000620040.032
cellular response to endogenous stimulusGO:0071495680.032
positive regulation of cellular amine metabolic processGO:003324000.032
aromatic compound biosynthetic processGO:00194382170.032
positive regulation of cellular catabolic processGO:003133130.032
regulation of protein targetingGO:190353320.032
negative regulation of intracellular protein transportGO:009031730.032
endomembrane system organizationGO:0010256130.032
morphogenesis of an epitheliumGO:00020093330.031
gtp catabolic processGO:000618420.031
negative regulation of cytoplasmic transportGO:190365020.031
organic acid metabolic processGO:0006082310.031
tube morphogenesisGO:00352393490.031
negative regulation of multicellular organismal processGO:0051241690.031
positive regulation of neuron differentiationGO:0045666120.031
immune system developmentGO:00025201910.031
guanosine containing compound metabolic processGO:190106840.031
regulation of anatomical structure morphogenesisGO:00226031300.031
protein targeting to nucleusGO:004474430.031
metal ion transportGO:0030001580.031
purine nucleoside monophosphate catabolic processGO:000912840.031
sensory perception of smellGO:000760820.031
regulation of gene expressionGO:00104682650.031
response to external biotic stimulusGO:0043207970.030
organonitrogen compound metabolic processGO:1901564740.030
glycoprotein metabolic processGO:0009100230.030
response to decreased oxygen levelsGO:0036293250.030
forebrain cell migrationGO:002188510.030
cellular response to starvationGO:000926710.030
purine ribonucleoside monophosphate catabolic processGO:000916940.030
response to bacteriumGO:0009617580.030
reactive nitrogen species metabolic processGO:200105700.030
hemopoiesisGO:00300971830.030
embryonic hemopoiesisGO:0035162530.030
embryonic heart tube morphogenesisGO:00031431080.029
positive regulation of cellular processGO:00485222010.029
cytokinesisGO:000091030.029
melanocyte differentiationGO:0030318260.029
nuclear migrationGO:000709730.029
synaptic vesicle localizationGO:009747910.029
negative regulation of macromolecule metabolic processGO:0010605760.029
negative regulation of protein localization to nucleusGO:190018120.029
programmed cell deathGO:00125011190.029
single organism metabolic processGO:00447102170.028
growthGO:00400071740.028
vasculature developmentGO:00019442780.028
protein localization to membraneGO:007265790.028
establishment of synaptic vesicle localizationGO:009748010.028
cellular aromatic compound metabolic processGO:00067252950.028
carbohydrate derivative metabolic processGO:1901135610.028
carboxylic acid metabolic processGO:0019752220.028
cellular protein complex assemblyGO:0043623190.028
positive regulation of neurogenesisGO:0050769240.028
negative regulation of cell differentiationGO:0045596460.027
response to transition metal nanoparticleGO:1990267280.027
phosphate containing compound metabolic processGO:00067961080.027
monovalent inorganic cation homeostasisGO:005506790.027
deathGO:00162651210.027
wnt signaling pathwayGO:0016055800.027
canonical wnt signaling pathwayGO:0060070480.027
cellular protein catabolic processGO:004425740.027
regulation of reactive oxygen species metabolic processGO:200037720.027
biosynthetic processGO:00090582940.027
regulation of carbohydrate metabolic processGO:000610940.027
negative regulation of protein kinase activityGO:000646940.026
blood vessel developmentGO:00015682460.026
positive regulation of biological processGO:00485182530.026
epithelium migrationGO:0090132250.026
macromolecule localizationGO:0033036540.026
cellular macromolecular complex assemblyGO:0034622240.026
epithelial cell migrationGO:0010631250.026
apoptotic processGO:00069151160.025
mitochondrion morphogenesisGO:007058420.025
regulation of protein polymerizationGO:003227120.025
gene expressionGO:00104672520.025
protein glycosylationGO:000648690.025
striated muscle cell differentiationGO:00511461290.025
actin filament bundle organizationGO:006157260.025
protein localization to nucleusGO:003450430.025
regulation of meiotic cell cycleGO:005144510.025
negative regulation of synapse assemblyGO:005196420.025
response to uvGO:000941130.024
phosphorus metabolic processGO:00067931090.024
striated muscle contractionGO:0006941120.024
regulation of nucleocytoplasmic transportGO:004682220.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
regulation of synaptic plasticityGO:004816710.024
negative regulation of kinase activityGO:003367340.024
sensory perceptionGO:0007600390.024
positive regulation of cell adhesionGO:004578510.024
central nervous system neuron developmentGO:0021954290.024
neuron projection extensionGO:1990138450.023
positive regulation of neuron apoptotic processGO:004352510.023
modification dependent protein catabolic processGO:001994130.023
embryonic heart tube developmentGO:00350501330.023
regulation of endocytosisGO:003010070.023
cation transportGO:0006812810.023
negative regulation of protein import into nucleusGO:004230820.023
response to organic substanceGO:00100331530.023
spindle localizationGO:0051653120.022
cellular protein complex disassemblyGO:004362410.022
epithelial tube morphogenesisGO:00605621480.022
transcription from rna polymerase ii promoterGO:0006366800.022
muscle fiber developmentGO:0048747520.022
positive regulation of secretionGO:005104710.022
negative regulation of protein phosphorylationGO:000193340.022
cellular response to hypoxiaGO:007145610.022
pronuclear migrationGO:003504610.022
mitotic cell cycleGO:0000278640.022
regulation of organelle organizationGO:0033043290.022
regulation of cellular protein metabolic processGO:0032268520.022
negative regulation of developmental processGO:0051093650.022
stem cell maintenanceGO:001982740.022
muscle system processGO:0003012200.021
regulation of protein ubiquitinationGO:003139630.021
homeostasis of number of cellsGO:0048872620.021
regulation of biosynthetic processGO:00098892500.021
regulation of immune system processGO:0002682340.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
extracellular matrix assemblyGO:008502910.021
regulation of transcription from rna polymerase ii promoterGO:00063571140.021
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.021
purine containing compound biosynthetic processGO:0072522200.021
protein complex subunit organizationGO:0071822460.021
endothelial cell migrationGO:0043542190.021
stress fiber assemblyGO:004314950.021
protein phosphorylationGO:0006468470.021
motor neuron axon guidanceGO:0008045230.021
positive regulation of protein complex assemblyGO:003133420.021
positive regulation of glucose importGO:004632610.021
transmembrane transportGO:00550851200.020
skeletal muscle organ developmentGO:0060538780.020
inorganic ion transmembrane transportGO:0098660570.020
response to radiationGO:0009314510.020
regulation of cell migration involved in sprouting angiogenesisGO:009004930.020
negative regulation of axon guidanceGO:190266810.020
regulation of phosphorylationGO:0042325260.020
golgi vesicle transportGO:004819330.019
cellular protein localizationGO:0034613200.019
fat soluble vitamin metabolic processGO:000677540.019
mitochondrial transportGO:000683920.019
cell cycle g2 m phase transitionGO:004483940.019
positive regulation of cell cycleGO:004578730.019
notch signaling pathwayGO:0007219350.019
pigment cell differentiationGO:0050931380.019
macroautophagyGO:001623610.019
cellular macromolecule localizationGO:0070727210.019
regulation of cell growthGO:0001558290.019
nucleic acid templated transcriptionGO:00976591810.019
blood vessel morphogenesisGO:00485142160.019
response to other organismGO:0051707970.019
nitric oxide metabolic processGO:004620920.019
thermosensory behaviorGO:004004010.019
negative regulation of apoptotic processGO:0043066550.019
locomotor rhythmGO:004547530.019
i kappab kinase nf kappab signalingGO:000724940.019
homeostatic processGO:00425921420.019
response to stressGO:00069502630.019
negative regulation of cellular component organizationGO:0051129160.018
negative regulation of neurogenesisGO:0050768200.018
amino acid transportGO:000686520.018
regulation of protein depolymerizationGO:190187910.018
primary neural tube formationGO:001402010.018
circulatory system processGO:0003013870.018
intrinsic apoptotic signaling pathwayGO:0097193200.018
regulation of dna replicationGO:000627530.018
regulation of growthGO:0040008420.018
multicellular organism growthGO:003526440.018
positive regulation of myeloid cell differentiationGO:004563920.018
regulation of cellular component movementGO:0051270550.018
negative regulation of phosphate metabolic processGO:0045936130.018
startle responseGO:000196440.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
chromosome organizationGO:0051276310.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
carbohydrate homeostasisGO:003350010.017
nucleocytoplasmic transportGO:000691340.017
nuclear transportGO:005116940.017
collagen metabolic processGO:003296320.017
negative regulation of secretion by cellGO:190353120.017
regulation of filopodium assemblyGO:005148920.017
cellular response to hormone stimulusGO:0032870390.017
anterior posterior pattern specificationGO:00099521520.017
cell deathGO:00082191210.017
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.017
cortical actin cytoskeleton organizationGO:003086610.017
ion transmembrane transportGO:0034220910.017

mfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.264
musculoskeletal system diseaseDOID:1700.102
cardiovascular system diseaseDOID:128700.053
muscle tissue diseaseDOID:6600.053
muscular diseaseDOID:008000000.053
cardiomyopathyDOID:005070000.053
heart diseaseDOID:11400.053
myopathyDOID:42300.053
intrinsic cardiomyopathyDOID:006003600.053
nervous system diseaseDOID:86300.034
organ system cancerDOID:005068600.018
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018