Danio rerio

0 known processes

timp2b

tissue inhibitor of metalloproteinase 2b

(Aliases: timp2l,zgc:65967,zgc:85799)

timp2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tube morphogenesisGO:00352393490.269
response to bacteriumGO:0009617580.258
locomotionGO:00400113130.248
blood vessel developmentGO:00015682460.201
neuron projection morphogenesisGO:00488121610.194
signal transductionGO:00071654550.185
immune system processGO:00023762410.184
lymph vessel developmentGO:0001945270.178
cellular component movementGO:00069283350.169
organic cyclic compound biosynthetic processGO:19013622230.165
cell migrationGO:00164772370.163
regulation of signal transductionGO:00099662250.148
regulation of immune system processGO:0002682340.144
morphogenesis of an epitheliumGO:00020093330.136
vasculature developmentGO:00019442780.132
regulation of response to stimulusGO:00485832690.124
extrinsic apoptotic signaling pathwayGO:009719130.122
taxisGO:00423301090.118
regulation of cell shapeGO:000836010.116
regulation of rna biosynthetic processGO:20011412130.115
regulation of macromolecule metabolic processGO:00602553170.112
response to stressGO:00069502630.101
regulation of bindingGO:005109830.096
positive regulation of cytokine productionGO:000181920.094
response to biotic stimulusGO:0009607970.091
neuron projection developmentGO:00311751800.089
negative regulation of signal transductionGO:0009968940.086
multicellular organismal metabolic processGO:004423620.085
cell substrate adhesionGO:003158940.084
positive regulation of cellular component biogenesisGO:004408930.083
defense responseGO:0006952470.080
regulation of chronic inflammatory responseGO:000267610.080
gastrulationGO:00073692080.077
modification dependent protein catabolic processGO:001994130.077
response to chemicalGO:00422213200.076
positive regulation of immune system processGO:0002684170.074
positive regulation of apoptotic signaling pathwayGO:200123510.073
defense response to other organismGO:0098542330.072
release of sequestered calcium ion into cytosolGO:005120930.069
digestive system developmentGO:00551232890.069
positive regulation of transportGO:005105020.069
cellular nitrogen compound metabolic processGO:00346412900.069
zymogen activationGO:003163830.068
digestive tract morphogenesisGO:00485462310.068
cell projection morphogenesisGO:00488582440.066
collagen metabolic processGO:003296320.066
ameboidal type cell migrationGO:00016671430.065
sensory organ developmentGO:00074233930.063
positive regulation of epithelial cell proliferationGO:005067910.063
regulation of metal ion transportGO:001095940.062
regulation of cell motilityGO:2000145460.062
cellular protein catabolic processGO:004425740.062
cell morphogenesisGO:00009022890.061
generation of neuronsGO:00486993850.061
nitrogen compound metabolic processGO:00068073190.059
embryonic organ morphogenesisGO:00485622740.058
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.058
regulation of signalingGO:00230512350.058
blood vessel morphogenesisGO:00485142160.057
regulation of cell proliferationGO:0042127370.057
symbiosis encompassing mutualism through parasitismGO:004440340.057
immune system developmentGO:00025201910.057
positive regulation of chronic inflammatory responseGO:000267810.056
regulation of nitrogen compound metabolic processGO:00511712510.056
embryonic heart tube morphogenesisGO:00031431080.055
ubiquitin dependent protein catabolic processGO:000651130.055
cellular biosynthetic processGO:00442492860.055
regulation of cellular component movementGO:0051270550.054
positive regulation of biological processGO:00485182530.054
response to drugGO:004249330.054
neuron differentiationGO:00301823530.053
positive regulation of response to stimulusGO:0048584800.053
axonogenesisGO:00074091520.053
regulation of cellular amino acid metabolic processGO:000652100.053
response to external biotic stimulusGO:0043207970.051
maintenance of locationGO:005123540.051
cell part morphogenesisGO:00329902460.051
nucleobase containing compound metabolic processGO:00061392740.050
regulation of epithelial cell proliferationGO:005067830.050
regulation of inflammatory responseGO:005072720.050
regulation of protein complex assemblyGO:004325430.050
determination of bilateral symmetryGO:00098552040.049
developmental programmed cell deathGO:001062340.049
embryonic organ developmentGO:00485683810.049
single organism localizationGO:19025782250.049
synaptic growth at neuromuscular junctionGO:005112420.049
multicellular organismal macromolecule metabolic processGO:004425920.048
ras protein signal transductionGO:000726570.048
regulation of cell communicationGO:00106462320.048
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.047
positive regulation of endothelial cell proliferationGO:000193810.047
regulation of localizationGO:00328791040.046
regulation of developmental processGO:00507932470.045
signal transduction in absence of ligandGO:003803410.044
regulation of nucleoside metabolic processGO:000911820.044
biosynthetic processGO:00090582940.044
embryonic limb morphogenesisGO:003032620.044
positive regulation of inflammatory responseGO:005072910.044
digestive tract developmentGO:00485652650.044
regulation of synapse organizationGO:005080730.043
positive regulation of cellular processGO:00485222010.043
axon developmentGO:00615641660.042
wound healingGO:0042060900.042
regulation of multicellular organismal developmentGO:20000262230.042
cellular amine metabolic processGO:004410620.040
negative regulation of biological processGO:00485193040.040
modification dependent macromolecule catabolic processGO:004363230.040
stem cell proliferationGO:007208940.040
peptidyl serine phosphorylationGO:001810510.040
establishment of protein localization to organelleGO:007259440.039
proteolysis involved in cellular protein catabolic processGO:005160330.039
cellular response to molecule of bacterial originGO:007121930.039
regulation of protein catabolic processGO:004217610.038
cellular component morphogenesisGO:00329893360.038
localization of cellGO:00516742440.038
positive regulation of catabolic processGO:000989640.038
regulation of endothelial cell proliferationGO:000193610.038
response to external stimulusGO:00096052640.038
single organism membrane fusionGO:004480120.038
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
hemopoiesisGO:00300971830.037
chronic inflammatory responseGO:000254410.037
positive regulation of epithelial cell migrationGO:001063420.037
cell deathGO:00082191210.037
regulation of anatomical structure morphogenesisGO:00226031300.037
organophosphate metabolic processGO:0019637370.037
apoptotic processGO:00069151160.037
nucleic acid metabolic processGO:00903042440.036
single organism metabolic processGO:00447102170.036
protein localization to nucleusGO:003450430.036
skeletal system developmentGO:00015011810.036
response to nutrientGO:000758430.036
organic acid metabolic processGO:0006082310.036
sequestering of calcium ionGO:005120830.036
cell surface receptor signaling pathwayGO:00071663250.036
regulation of cell migrationGO:0030334400.036
regulation of synapse assemblyGO:005196330.036
camera type eye developmentGO:00430102220.036
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.035
oxoacid metabolic processGO:0043436310.035
response to woundingGO:00096111160.035
regulation of apoptotic processGO:0042981980.035
determination of heart left right asymmetryGO:00613711170.034
regulation of protein bindingGO:004339330.034
positive regulation of secretion by cellGO:190353210.034
regulation of extrinsic apoptotic signaling pathwayGO:200123630.034
regulation of cytokine productionGO:000181730.033
response to oxygen levelsGO:0070482250.033
regulation of cytoplasmic transportGO:190364940.033
sprouting angiogenesisGO:0002040530.033
positive regulation of wound healingGO:009030310.033
response to alkaloidGO:004327920.032
tissue remodelingGO:004877140.032
cell motilityGO:00488702440.032
rna biosynthetic processGO:00327741810.032
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.031
positive regulation of immune effector processGO:000269930.031
protein polymerizationGO:005125840.031
carboxylic acid metabolic processGO:0019752220.030
cell morphogenesis involved in neuron differentiationGO:00486671630.030
axon guidanceGO:0007411860.030
actin filament based movementGO:003004810.030
sensory perception of painGO:001923310.030
cellular component assemblyGO:00226071700.030
positive regulation of dna metabolic processGO:005105410.030
specification of symmetryGO:00097992040.030
positive regulation of response to woundingGO:190303650.030
establishment of localizationGO:00512342440.029
agingGO:000756820.029
larval developmentGO:000216420.029
regulation of transportGO:0051049450.029
positive regulation of macromolecule biosynthetic processGO:0010557590.029
response to lipopolysaccharideGO:0032496130.029
phagocytosisGO:000690930.029
positive regulation of epithelial cell differentiationGO:003085820.029
regulation of cellular ketone metabolic processGO:001056570.029
cellular macromolecule metabolic processGO:00442603910.028
lymphangiogenesisGO:0001946250.028
phagocytosis engulfmentGO:000691110.028
regulation of establishment of protein localizationGO:007020140.028
chemotaxisGO:00069351040.028
gene expressionGO:00104672520.028
regulation of metabolic processGO:00192223590.028
positive regulation of developmental processGO:0051094500.028
lipid storageGO:001991510.028
positive regulation of cell cycleGO:004578730.028
cell morphogenesis involved in differentiationGO:00009041950.028
retina development in camera type eyeGO:00600411460.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
positive regulation of signal transductionGO:0009967560.028
neuron projection guidanceGO:0097485860.027
cellular response to external stimulusGO:007149620.027
positive regulation of nitrogen compound metabolic processGO:0051173690.027
positive regulation of cell adhesionGO:004578510.027
gtp metabolic processGO:004603940.027
positive regulation of protein complex assemblyGO:003133420.027
positive regulation of macromolecule metabolic processGO:0010604930.027
leukocyte homeostasisGO:000177620.027
regulation of cell substrate adhesionGO:001081010.026
macrophage chemotaxisGO:004824630.026
heterocycle biosynthetic processGO:00181302150.026
proteasomal protein catabolic processGO:001049820.026
intestinal cholesterol absorptionGO:003029920.026
regulation of erk1 and erk2 cascadeGO:007037240.026
epiboly involved in gastrulation with mouth forming secondGO:0055113350.026
positive regulation of secretionGO:005104710.026
central nervous system developmentGO:00074173870.025
organonitrogen compound metabolic processGO:1901564740.025
cortical cytoskeleton organizationGO:003086510.025
protein metabolic processGO:00195381830.025
negative regulation of signalingGO:0023057960.025
regulation of transcription dna templatedGO:00063552130.025
apoptotic signaling pathwayGO:0097190230.025
epithelial cell differentiationGO:00308551160.025
cytokinesisGO:000091030.025
cytosolic calcium ion transportGO:006040130.025
cellular macromolecule biosynthetic processGO:00346452240.025
nucleic acid templated transcriptionGO:00976591810.024
regulation of erythrocyte differentiationGO:004564620.024
positive regulation of gtp catabolic processGO:003312610.024
phosphorus metabolic processGO:00067931090.024
response to other organismGO:0051707970.024
regulation of cell deathGO:00109411030.024
cell migration involved in gastrulationGO:0042074790.024
cellular carbohydrate metabolic processGO:004426240.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
eye morphogenesisGO:00485921440.023
endoderm developmentGO:0007492490.023
neuron developmentGO:00486662620.023
single organism organelle organizationGO:19025891990.023
regulation of calcium ion transportGO:005192420.023
regulation of gene expressionGO:00104682650.023
cellular protein metabolic processGO:00442671290.023
regulation of dendrite morphogenesisGO:004881430.022
erk1 and erk2 cascadeGO:007037140.022
positive regulation of myeloid cell differentiationGO:004563920.022
positive regulation of cellular component movementGO:0051272110.022
embryonic hemopoiesisGO:0035162530.022
response to organic substanceGO:00100331530.022
multi organism processGO:00517041340.022
tissue migrationGO:0090130370.022
cortical actin cytoskeleton organizationGO:003086610.022
cellular response to radiationGO:007147840.022
organelle fusionGO:004828430.022
negative regulation of nitrogen compound metabolic processGO:0051172590.022
negative regulation of cellular metabolic processGO:0031324770.021
positive regulation of synapse assemblyGO:005196510.021
g1 s transition of mitotic cell cycleGO:000008210.021
regulation of reproductive processGO:200024140.021
regulation of protein localization to nucleusGO:190018020.021
muscle structure developmentGO:00610611960.021
protein localization to plasma membraneGO:007265910.021
innate immune responseGO:0045087130.021
eye developmentGO:00016542770.021
sensory organ morphogenesisGO:00905962000.021
purine nucleotide metabolic processGO:0006163270.021
regulation of cellular amine metabolic processGO:003323800.021
positive regulation of nucleoside metabolic processGO:004597910.021
cell substrate junction assemblyGO:000704420.021
glucose importGO:004632320.020
regulation of locomotionGO:0040012550.020
amine metabolic processGO:000930820.020
nucleocytoplasmic transportGO:000691340.020
epithelial tube morphogenesisGO:00605621480.020
retinal ganglion cell axon guidanceGO:0031290350.020
cellular component disassemblyGO:002241110.020
cellular ketone metabolic processGO:0042180110.020
regulation of protein polymerizationGO:003227120.020
negative regulation of immune responseGO:005077720.020
protein processingGO:0016485120.020
negative regulation of cell communicationGO:0010648960.019
positive regulation of erk1 and erk2 cascadeGO:007037420.019
organelle organizationGO:00069962270.019
angiogenesisGO:00015251580.019
regulation of programmed cell deathGO:00430671010.019
cellular aromatic compound metabolic processGO:00067252950.019
endocrine processGO:005088620.019
response to abiotic stimulusGO:00096281220.019
negative regulation of protein phosphorylationGO:000193340.019
regulation of hormone secretionGO:004688320.019
mesenchyme developmentGO:00604851270.019
transportGO:00068102200.019
response to ketoneGO:190165410.019
cellular amino acid metabolic processGO:000652070.019
small gtpase mediated signal transductionGO:000726480.019
epibolyGO:0090504410.019
negative regulation of immune system processGO:000268370.019
response to carbohydrateGO:000974330.018
cellular response to chemical stimulusGO:00708871570.018
protein polyubiquitinationGO:000020940.018
sensory perception of chemical stimulusGO:000760630.018
regulation of cellular biosynthetic processGO:00313262450.018
aromatic compound biosynthetic processGO:00194382170.018
embryonic skeletal system developmentGO:0048706970.018
regulation of vasculature developmentGO:1901342330.018
neuromast developmentGO:0048884460.018
interspecies interaction between organismsGO:004441940.018
nephron epithelium morphogenesisGO:007208810.018
immune responseGO:0006955280.018
determination of left right symmetryGO:00073681790.018
transcription dna templatedGO:00063511810.018
signal transduction by phosphorylationGO:0023014180.018
response to glucocorticoidGO:005138410.018
regulation of dendrite developmentGO:005077330.018
cellular protein modification processGO:00064641000.018
regulation of protein transportGO:005122330.018
embryonic heart tube developmentGO:00350501330.017
brain developmentGO:00074202930.017
regulation of stem cell differentiationGO:200073640.017
glucose homeostasisGO:004259310.017
positive regulation of cellular catabolic processGO:003133130.017
negative regulation of intracellular protein transportGO:009031730.017
defense response to bacteriumGO:0042742220.017
gtp catabolic processGO:000618420.017
response to glucoseGO:000974930.017
negative regulation of axon regenerationGO:004868140.017
liver developmentGO:0001889960.017
deathGO:00162651210.017
regulation of cell projection assemblyGO:006049140.017
positive regulation of cellular protein metabolic processGO:0032270220.017
regulation of cell activationGO:005086510.017
head developmentGO:00603223030.017
positive regulation of exocytosisGO:004592110.017
regulation of rho protein signal transductionGO:003502320.017
positive regulation of locomotionGO:0040017140.017
positive regulation of molecular functionGO:0044093330.017
regulation of multicellular organismal processGO:00512392770.017
regulation of biosynthetic processGO:00098892500.017
organic cyclic compound metabolic processGO:19013603010.017
metal ion homeostasisGO:0055065260.017
negative regulation of response to stimulusGO:00485851040.017
convergent extension involved in gastrulationGO:0060027710.017
proteolysisGO:0006508380.017
positive regulation of biosynthetic processGO:0009891680.016
regulation of jak stat cascadeGO:004642530.016
negative regulation of angiogenesisGO:001652570.016
response to uvGO:000941130.016
response to molecule of bacterial originGO:0002237140.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
positive regulation of programmed cell deathGO:0043068290.016
programmed cell deathGO:00125011190.016
response to corticosteroidGO:003196010.016
response to vitaminGO:003327330.016
locomotor rhythmGO:004547530.016
carbohydrate homeostasisGO:003350010.016
positive regulation of gtpase activityGO:004354710.016
ion transmembrane transportGO:0034220910.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
actin filament polymerizationGO:003004120.016
lymph vessel morphogenesisGO:0036303250.016
regulation of response to cytokine stimulusGO:006075930.016
regulation of nucleocytoplasmic transportGO:004682220.016
g protein coupled receptor signaling pathwayGO:0007186740.016
embryo development ending in birth or egg hatchingGO:00097922710.016
membrane invaginationGO:001032410.016
phosphorylationGO:0016310690.016
positive regulation of rna metabolic processGO:0051254590.016
cell projection organizationGO:00300302840.016
establishment of protein localization to plasma membraneGO:009000210.016
response to lipidGO:0033993600.016
stem cell developmentGO:0048864820.016
cellular response to light stimulusGO:007148240.015
myeloid leukocyte migrationGO:0097529120.015
membrane fusionGO:006102520.015
immunoglobulin productionGO:000237710.015
stem cell maintenanceGO:001982740.015
response to hexoseGO:000974630.015
response to monosaccharideGO:003428430.015
cell cycle g1 s phase transitionGO:004484310.015
skeletal muscle organ developmentGO:0060538780.015
positive regulation of stress activated mapk cascadeGO:003287430.015
macromolecule biosynthetic processGO:00090592270.015
peptidyl serine modificationGO:001820920.015
nephron tubule morphogenesisGO:007207810.015
regulation of cellular component organizationGO:0051128860.015
ion transportGO:00068111140.015
endomembrane system organizationGO:0010256130.015
germ line stem cell maintenanceGO:003071820.015
positive regulation of cellular amine metabolic processGO:003324000.015
post embryonic organ developmentGO:004856940.014
pigmentationGO:0043473850.014
multi organism cellular processGO:004476420.014
regulation of intracellular protein transportGO:003315730.014
regulation of rna metabolic processGO:00512522240.014
organ regenerationGO:003110010.014
cell cycle arrestGO:000705010.014
nitric oxide metabolic processGO:004620920.014
negative regulation of cytoplasmic transportGO:190365020.014
protein homooligomerizationGO:005126030.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
intracellular signal transductionGO:0035556850.014
negative regulation of protein transportGO:005122430.014
negative regulation of cell deathGO:0060548600.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
regulation of multicellular organism growthGO:004001440.014
maternal determination of anterior posterior axis embryoGO:000835840.014
meiotic cell cycle processGO:190304630.014
response to oxygen containing compoundGO:1901700550.014
negative regulation of blood circulationGO:190352320.014
regulation of tube sizeGO:003515020.014
exocytosisGO:000688710.013
rna metabolic processGO:00160702190.013
positive regulation of leukocyte migrationGO:000268720.013
cognitionGO:005089010.013
leukocyte proliferationGO:007066110.013
regulation of wound healingGO:006104120.013
mitochondrion organizationGO:000700540.013
positive regulation of map kinase activityGO:004340630.013
regulation of molecular functionGO:0065009700.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
small molecule metabolic processGO:0044281770.013
macromolecule modificationGO:00434121110.013
gastrulation with mouth forming secondGO:0001702440.013
positive regulation of cellular metabolic processGO:0031325940.013
single organism nuclear importGO:190259330.013
cytoskeleton dependent cytokinesisGO:006164030.013
nuclear transportGO:005116940.013
regulation of cell growthGO:0001558290.013
protein targeting to nucleusGO:004474430.013
single organism membrane organizationGO:0044802200.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
regulation of filopodium assemblyGO:005148920.013
negative regulation of protein complex assemblyGO:003133310.013
retina vasculature development in camera type eyeGO:006129820.013
mononuclear cell proliferationGO:003294310.013
single organism biosynthetic processGO:0044711710.013
hormone transportGO:000991420.013
regulation of sequestering of calcium ionGO:005128240.013
positive regulation of cytoskeleton organizationGO:005149530.013
organic substance biosynthetic processGO:19015762890.013
production of molecular mediator of immune responseGO:000244020.013
negative regulation of apoptotic processGO:0043066550.013
regulation of cellular metabolic processGO:00313233200.013
primitive hemopoiesisGO:0060215270.012
positive regulation of nucleotide catabolic processGO:003081310.012
developmental cell growthGO:0048588520.012
protein modification processGO:00362111000.012
cell chemotaxisGO:0060326170.012
apoptotic process involved in developmentGO:190274220.012
regulation of response to oxidative stressGO:190288220.012
cellular response to starvationGO:000926710.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
nucleobase containing compound biosynthetic processGO:00346542050.012
viral processGO:001603210.012
renal filtrationGO:0097205100.012
synaptic target recognitionGO:000803910.012
osteoclast differentiationGO:003031610.012
carbohydrate biosynthetic processGO:001605110.012
ovulation cycleGO:004269820.012
myeloid cell homeostasisGO:0002262560.012
regulation of nucleotide catabolic processGO:003081120.012
regulation of cell projection organizationGO:0031344440.012
protein import into nucleusGO:000660630.012
regulation of gtp catabolic processGO:003312420.012
protein dephosphorylationGO:000647030.012
membrane lipid biosynthetic processGO:004646720.012
homeostasis of number of cellsGO:0048872620.011
myeloid cell developmentGO:0061515320.011
regulation of stem cell proliferationGO:007209120.011
heterocycle metabolic processGO:00464832900.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
positive regulation of cell proliferationGO:0008284150.011
regulation of dna templated transcription in response to stressGO:004362000.011
regulation of neutrophil extravasationGO:200038910.011
b cell differentiationGO:003018310.011
regulation of gtpase activityGO:004308720.011
positive regulation of signalingGO:0023056560.011
regulation of macromolecule biosynthetic processGO:00105562250.011
neuron projection extensionGO:1990138450.011
autophagyGO:000691440.011
cellular response to stressGO:0033554620.011
mechanosensory behaviorGO:000763820.011
positive regulation of stem cell proliferationGO:200064810.011
regulation of establishment or maintenance of cell polarityGO:003287820.011
regulation of apoptotic signaling pathwayGO:2001233120.011
regulation of phosphate metabolic processGO:0019220430.011
renal system developmentGO:0072001940.011
skeletal system morphogenesisGO:00487051020.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
cell agingGO:000756920.011
regulation of primary metabolic processGO:00800903110.011
transcription from rna polymerase ii promoterGO:0006366800.011
guanosine containing compound metabolic processGO:190106840.011
spermatid differentiationGO:004851520.011
cellular response to biotic stimulusGO:007121630.011
regulation of cellular protein metabolic processGO:0032268520.011
cellular response to organic substanceGO:00713101050.011
chordate embryonic developmentGO:00430092710.011
regulation of mitochondrion organizationGO:001082110.011
negative regulation of innate immune responseGO:004582420.011

timp2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.026
organ system cancerDOID:005068600.026
cancerDOID:16200.026
disease of anatomical entityDOID:700.020
disease of metabolismDOID:001466700.015
nervous system diseaseDOID:86300.011
immune system diseaseDOID:291400.011